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1

Bloedel, Smith Janis, and Moloney-Harmon Pat, eds. Critical care nursing of infants and children. Philadelphia: W.B. Saunders, 1996.

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2

Pat, Moloney-Harmon, ed. Critical care nursing of infants and children. 2nd ed. Philadelphia: W.B. Saunders, 2001.

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3

Vergara, Elsie. Foundations for practice in the neonatal intensive care unit and early interventions: A self-guided practice manual. Rockville, MD: AOTA, 1993.

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4

Whitaker, Kent B. Comprehensive perinatal & pediatric respiratory care. 2nd ed. Albany: Delmar Publishers, 1997.

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5

Comprehensive perinatal and pediatric respiratory care. 3rd ed. Albany: Delmar Publishers, 2001.

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6

Comprehensive perinatal and pediatric respiratory care. Albany, N.Y: Delmar Publishers, 1992.

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7

Daniel, Teres, ed. Gatekeeping in the intensive care unit. Chicago, Ill: Health Administration Press, 1997.

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8

Esquinas, Antonio Matías, ed. Humidification in the Intensive Care Unit. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-02974-5.

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9

Juffermans, Nicole P., and Timothy S. Walsh, eds. Transfusion in the Intensive Care Unit. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-08735-1.

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10

Netzer, Giora, ed. Families in the Intensive Care Unit. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94337-4.

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11

Jankowich, Matthew, and Eric Gartman, eds. Ultrasound in the Intensive Care Unit. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-1723-5.

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12

H. K. F. Van Saene. Infection control in the intensive care unit. 3rd ed. Milan: Springer, 2012.

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13

Soneja, Manish, and Puneet Khanna, eds. Infectious Diseases in the Intensive Care Unit. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-4039-4.

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14

Humphreys, Hilary, Bob Winter, and Mical Paul. Infections in the Adult Intensive Care Unit. London: Springer London, 2013. http://dx.doi.org/10.1007/978-1-4471-4318-5.

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15

van Saene, H. K. F., M. A. De La Cal, and L. Silvestri, eds. Infection Control in the Intensive Care Unit. Milano: Springer Milan, 2005. http://dx.doi.org/10.1007/b139061.

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16

Meiser, Andreas. Inhaled sedation in the intensive care unit. Wiesbaden: Springer Fachmedien Wiesbaden, 2019. http://dx.doi.org/10.1007/978-3-658-27352-1.

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17

Barnes, R. A., and D. W. Warnock, eds. Fungal Infection in the Intensive Care Unit. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0977-6.

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18

van Saene, Hendrick K. F., Luciano Silvestri, Miguel A. de la Cal, and Antonino Gullo, eds. Infection Control in the Intensive Care Unit. Milano: Springer Milan, 2012. http://dx.doi.org/10.1007/978-88-470-1601-9.

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19

Tsubokawa, Takashi, Anthony Marmarou, Claudia Robertson, and Graham Teasdale, eds. Neurochemical Monitoring in the Intensive Care Unit. Tokyo: Springer Japan, 1995. http://dx.doi.org/10.1007/978-4-431-68522-7.

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20

Nadel, Simon, ed. Infectious Diseases in the Pediatric Intensive Care Unit. London: Springer London, 2008. http://dx.doi.org/10.1007/978-1-84628-917-0.

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21

Wang, Douyou. Indices of sedation in the intensive care unit. Manchester: University of Manchester, 1993.

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22

Jouvet, Philippe, and Fernando Alvarez, eds. Liver Diseases in the Pediatric Intensive Care Unit. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-79132-2.

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23

Evidence-based competency management for the intensive care unit. 2nd ed. Marblehead, MA: HCPro, 2008.

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24

Feldman, Charles, and George A. Sarosi, eds. Tropical and Parasitic Infections in the Intensive Care Unit. Boston, MA: Springer US, 2005. http://dx.doi.org/10.1007/b101401.

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25

Park, G. R. Fighting for life: An introduction to the intensive care unit. Oxford: Oxford University Press, 1996.

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26

Sladen, Arnold. Invasive monitoring and its complications in the intensive care unit. St. Louis: Mosby, 1990.

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27

Afreen, Samina, Hector R. Wong, and Marian G. Michaels. Infections in the Intensive Care Unit. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199918027.003.0015.

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Infections are a frequent problem for children cared for in the intensive care setting. The child can have a primary infectious condition that is severe enough to require hospitalization in the intensive care unit (ICU). Alternatively once in the ICU setting children are at risk for nosocomial infections due to a need for catheters that breech the cutaneous barriers, mechanical ventilation and exposures to blood products. Finally, many children sick enough to be in an intensive care setting have underlying immune deficiencies which put that at increased risk. This chapter reviews some of the major underlying infections that lead to intensive care stays as well as the major nosocomial infections which can plague our patients.
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28

Infectious Diseases In The Pediatric Intensive Care Unit. Springer, 2008.

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29

Nadel, Simon. Infectious Diseases in the Pediatric Intensive Care Unit. Springer, 2016.

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30

Younger, Mary Elizabeth Mechling. COPING STRATEGIES OF PRESCHOOL-AGED CHILDREN HOSPITALIZED IN A PEDIATRIC INTENSIVE CARE UNIT. 1992.

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31

Moloney-Harmon, Patricia A., and Martha A. Q. Curley. Critical Care Nursing of Infants and Children. 2nd ed. Saunders, 2001.

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32

Critical care nursing of infants and children. 2nd ed. Philadelphia: W.B. Saunders, 2001.

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33

Colville, Gillian. Supporting Pediatric Patients and Their Families during and after Intensive Care Treatment. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199398690.003.0007.

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This chapter shows how the observations and recommendations in the adult intensive care unit (ICU) literature are relevant to the provision of services for pediatric intensive care patients and their families. Two relevant models of service currently in use in pediatric settings are presented, illustrated with clinical examples. Models of care in pediatrics have traditionally been more family-focused than those in adult settings. In the acute stage of medical treatment in the pediatric ICU, the emphasis, from a psychological perspective, is primarily preventative and initially focused on parental reactions at a time when the child is usually too unwell or sedated to communicate with directly. As the child’s condition stabilizes, delirium and associated frightening experiences should be addressed. Children may cope better if provided an age-appropriate storybook explaining what has happened. In the longer term, it is important to speak to children directly about their critical illness experiences, and to monitor children’s and parents’ emotional reactions over time. Trauma-focused cognitive-behavioral and narrative therapies may be helpful.
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34

Shein, Steven L., and Robert S. B. Clark. Neurocritical Care. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199918027.003.0009.

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Brain injury is the most common proximate cause of death in pediatric intensive care units. For children who survive critical illness, long-standing brain damage and residual brain dysfunction can affect quality of life significantly. Therefore, minimizing neurological injury to improve patient outcomes is a priority of neurocritical care. This may be accomplished by implementing specific targeted therapies, avoiding pathophysiological conditions that exacerbate neurological injury, and using a multidisciplinary team that focuses on contemporary care of children with neurological injury and disease. This chapter reviews pertinent anatomy and physiology; general principles of pediatric neurocritical care; and specifics for caring for children with traumatic brain injury, hypoxic–ischemic encephalopathy, status epilepticus, meningitis/encephalitis, stroke, and acute hydrocephalus.
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35

Zuppa, Athena. Pediatric Critical Care Pharmacology. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199918027.003.0018.

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This chapter includes essential information about the basic principles of pharmacology and relates them to unique characteristics of critically ill children. The author provides a succinct summary of fundamentals of pharmacokinetics and pharmacodynamics, including absorption, distribution, metabolism, and elimination. First- and zero-order kinetics are reviewed, along with examples of drugs commonly used in the intensive care unit that follow those patterns of metabolism. The chapter also includes crucial information about how development from birth affects the various aspects of pharmacology. The effects on drug metabolism of shock, and renal and hepatic dysfunction are provided, along with drug–drug interactions, including commonly used drugs in critical care that induce or inhibit enzyme activity.
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36

C, Arroliga Alejandro, ed. Intensive care unit complications. Philadelphia: Saunders, 1999.

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37

Jenkins, Ian A., and David A. Rowney. Resuscitation, stabilization, and transfer of sick and injured children. Edited by Jonathan G. Hardman and Neil S. Morton. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0074.

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Even though anaesthetists may not regard themselves as specialists in the care of critically ill children, they are still at the forefront of the immediate care of critically ill children. Whether they have developed an interest in paediatric anaesthesia or because they have subspecialized in general intensive care, anaesthetists will find themselves called upon by colleagues in the emergency department or in paediatrics to exercise the knowledge and skills that no other group in the hospital possess. Additionally, when these children need to be moved either to a scanner or hyper-acutely to a tertiary unit (e.g. for neurosurgical intervention), then the skills and specific knowledge of the anaesthetist will be called upon again. These elements are recognized in the syllabi of both the Fellowship of the Royal College of Anaesthetists and the Fellowship of the Faculty of Intensive Care Medicine. This chapter gives the background to the characteristics of critically ill children, sets out the important elements of the conditions that will be commonly encountered, and provides a full résumé of the preparations that transferring teams will need in terms of personnel, their knowledge, skills, and equipment, and also a full exploration of the various methods of transport, road ambulance, rotary- and fixed-wing aircraft, and what all these entail for the clinical team.
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38

Andropoulos, Dean B. Management of Children with Congenital Heart Disease for Noncardiac Surgery. Edited by Erin S. Williams, Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi A. O. Aina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.003.0025.

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Congenital heart disease (CHD) patients are increasingly presenting for noncardiac surgery, and the anesthesiologist must possess an understanding of the major classes of CHD and their pathophysiology, as well as surgical approaches for correction or palliation. A thorough preoperative evaluation and anesthetic plan, including invasive monitoring, inotropic support, blood transfusion, endocarditis prophylaxis, pacemaker/defibrillator functioning, and intensive care unit admission must be developed, and include a multidisciplinary team. Each patient has a unique pathophysiology and a systematic approach to understanding hemodynamic consequences, and developing hemodynamic goals for the anesthetic will improve the potential to minimize anesthetic complications and ensure the best possible outcomes.
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39

Sagert, Kristin Marie. SURGICAL INTENSIVE CARE UNIT SURROGATE SATISFACTION STUDY (INTENSIVE CARE). 1991.

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40

(Editor), D. Langrehr, and D. Reis Miranda (Editor), eds. Intensive Care Unit (International Congress). Elsevier, 1986.

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41

Garner, Justin, and David Treacher. Intensive care unit and ventilation. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199657742.003.0009.

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Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are characterized by rapidly developing hypoxaemic respiratory failure and bilateral pulmonary infiltrates on chest X-ray. ALI/ARDS are a relatively frequent diagnosis in protracted-stay patients in the intensive care unit. The pathology is a non-specific response to a wide variety of insults. Impaired gas exchange, ventilation-perfusion mismatch, and reduced compliance ensue. Mechanical ventilation is the mainstay of management, along with treatment of the underlying cause. Mortality remains very high at around 40%. The condition is challenging to treat. Injury to the lungs, indistinguishable from that of ARDS, has been attributed to the use of excessive tidal volumes, pressures, and repeated opening and collapsing of alveoli. Lung-protective strategies aim to minimize the effects of ventilator-induced lung injury. Use of low tidal volume ventilation has been shown to improve mortality. Emerging ventilatory therapies include high-frequency oscillatory ventilation and extracorporeal membrane oxygenation.
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42

(Editor), Paul N. Lanken, C. William Hanson (Editor), and Scott Manaker (Editor), eds. The Intensive Care Unit Manual. Saunders, 2000.

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43

Wise, Matt, and Paul Frost. Terminal care in the intensive care unit. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0153.

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In the UK, around 10%–20% of all patients admitted to the intensive care unit (ICU) do not survive while, in the United States, it has been estimated that 22% of all deaths occur in an ICU. Therefore, terminal or palliative care is as important as any of the life-saving interventions that occur in the ICU. The goal of palliative care is to achieve a good death. In the ICU, the switch from care with curative intent to palliation occurs when it becomes obvious that the patient is not responding to treatment. Typically, this is manifest by deteriorating physiology and escalating organ support in the setting of overwhelming disease or injury. It is predominantly expert opinion (consensus amongst treating medical and nursing teams) that determines the point at which the patient is recognized as not responding to treatment and, in fact, dying. This chapter covers the ethical considerations, communication, family disagreement, organ donation, withdrawal of therapies, care after death, and diagnosing death.
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44

Pneumonia in the intensive care unit. Philadelphia: Saunders, 1995.

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45

Patti, Eisenberg, and Quinn Andrea D'Amato, eds. Nutrition in the intensive care unit. Philadelphia: Saunders, 1993.

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46

Juffermans, Nicole P., and Timothy S. Walsh. Transfusion in the Intensive Care Unit. Springer, 2014.

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47

Manaker, Scott, Paul N. Lanken, C. William Hanson, Benjamin A. Kohl, and Hanson C. William III. Intensive Care Unit Manual E-Book. Elsevier - Health Sciences Division, 2013.

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48

Wise, Matt, and Paul Frost. Role of the intensive care unit. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0148.

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The intensive care unit (ICU) can be defined as an area reserved for patients with potential or established organ failure and has the facilities for the diagnosis, prevention, and treatment of multi-organ failure. Usually, the ICU is located in close proximity to A & E, the radiology department, and the operating theatres, as it is between these areas that patient flows are greatest. In large urban hospitals, there may be more than one ICU, some of which serve specific patient populations, such as paediatrics, neurosurgery, cardiothoracic surgery, liver failure, and burns. Many hospitals also have high-dependency units (HDUs) that offer higher nurse-to-patient ratios and more advanced monitoring than a general wards does, as well as limited organ support. In the UK, the distinctions between ICU, HDU, and general ward have been abandoned in favour of a classification based on the patient’s needs rather than their location.
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49

Quinn, Tom, and Eva Swahn. The intensive cardiac care unit team. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0011.

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Effective, safe health care is a multidisciplinary undertaking. From its inception, half a century ago, the concept of intensive coronary (now cardiac) care has drawn on the expertise of a range of professionals, particularly physicians working closely with nurses. As the evidence base for some aspects of the intensive cardiac care unit care has developed, the intensive cardiac care unit, in some instances, has striking similarities to the general intensive care unit, while paradoxically traditional intensive cardiac care unit functions have been devolved to other parts of the health care system such as the emergency department or pre-hospital care, and the concept of critical care ‘outreach’ has been further developed to take the expertise to patients on the general ward or even in the pre-hospital phase. With more intensive treatment policies for older people becoming the norm, the range of multi-comorbidities to be addressed by the clinical team requires input from a range of other specialties. Moreover, the increasing complexity of diagnostic and interventional techniques requires close collaboration with laboratory and imaging personnel. Thus, the intensive cardiac care unit team arguably extends beyond staff working solely within the physical structure of the intensive cardiac care unit to encompass a range of other professional and support staff, both within and outside the hospital setting.
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50

Quinn, Tom, and Eva Swahn. The intensive cardiac care unit team. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0011_update_001.

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Effective, safe health care is a multidisciplinary undertaking. From its inception, half a century ago, the concept of intensive coronary (now cardiac) care has drawn on the expertise of a range of professionals, particularly physicians working closely with nurses. As the evidence base for some aspects of the intensive cardiac care unit care has developed, the intensive cardiac care unit, in some instances, has striking similarities to the general intensive care unit, while paradoxically traditional intensive cardiac care unit functions have been devolved to other parts of the health care system such as the emergency department or pre-hospital care, and the concept of critical care ‘outreach’ has been further developed to take the expertise to patients on the general ward or even in the pre-hospital phase. With more intensive treatment policies for older people becoming the norm, the range of multi-comorbidities to be addressed by the clinical team requires input from a range of other specialties. Moreover, the increasing complexity of diagnostic and interventional techniques requires close collaboration with laboratory and imaging personnel. Thus, the intensive cardiac care unit team arguably extends beyond staff working solely within the physical structure of the intensive cardiac care unit to encompass a range of other professional and support staff, both within and outside the hospital setting.
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