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1

Yang, Bo, Yun Xie, Maojuan Guo, Mitchell H. Rosner, Hongtao Yang, and Claudio Ronco. "Nephrotoxicity and Chinese Herbal Medicine." Clinical Journal of the American Society of Nephrology 13, no. 10 (April 3, 2018): 1605–11. http://dx.doi.org/10.2215/cjn.11571017.

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Chinese herbal medicine has been practiced for the prevention, treatment, and cure of diseases for thousands of years. Herbal medicine involves the use of natural compounds, which have relatively complex active ingredients with varying degrees of side effects. Some of these herbal medicines are known to cause nephrotoxicity, which can be overlooked by physicians and patients due to the belief that herbal medications are innocuous. Some of the nephrotoxic components from herbs are aristolochic acids and other plant alkaloids. In addition, anthraquinones, flavonoids, and glycosides from herbs also are known to cause kidney toxicity. The kidney manifestations of nephrotoxicity associated with herbal medicine include acute kidney injury, CKD, nephrolithiasis, rhabdomyolysis, Fanconi syndrome, and urothelial carcinoma. Several factors contribute to the nephrotoxicity of herbal medicines, including the intrinsic toxicity of herbs, incorrect processing or storage, adulteration, contamination by heavy metals, incorrect dosing, and interactions between herbal medicines and medications. The exact incidence of kidney injury due to nephrotoxic herbal medicine is not known. However, clinicians should consider herbal medicine use in patients with unexplained AKI or progressive CKD. In addition, exposure to herbal medicine containing aristolochic acid may increase risk for future uroepithelial cancers, and patients require appropriate postexposure screening.
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2

Drew, Anna, Ian M. Whyte, Andrew H. Dawson, Alan Benoussan, and Stephen P. Myers. "Chinese Herbal Medicine." Australian Journal of Hospital Pharmacy 30, no. 2 (April 2000): 71–72. http://dx.doi.org/10.1002/jppr200030271a.

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3

Han, Ke, Lei Zhang, Miao Wang, Rui Zhang, Chunyu Wang, and Chengzhi Zhang. "Prediction Methods of Herbal Compounds in Chinese Medicinal Herbs." Molecules 23, no. 9 (September 10, 2018): 2303. http://dx.doi.org/10.3390/molecules23092303.

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Chinese herbal medicine has recently gained worldwide attention. The curative mechanism of Chinese herbal medicine is compared with that of western medicine at the molecular level. The treatment mechanism of most Chinese herbal medicines is still not clear. How do we integrate Chinese herbal medicine compounds with modern medicine? Chinese herbal medicine drug-like prediction method is particularly important. A growing number of Chinese herbal source compounds are now widely used as drug-like compound candidates. An important way for pharmaceutical companies to develop drugs is to discover potentially active compounds from related herbs in Chinese herbs. The methods for predicting the drug-like properties of Chinese herbal compounds include the virtual screening method, pharmacophore model method and machine learning method. In this paper, we focus on the prediction methods for the medicinal properties of Chinese herbal medicines. We analyze the advantages and disadvantages of the above three methods, and then introduce the specific steps of the virtual screening method. Finally, we present the prospect of the joint application of various methods.
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Tang, Shiyi, Jiahao Jue, and Yifan Lin. "Study on Identification Method of Chinese Herbal Medicine based on Infrared Spectroscopy Characteristics." Highlights in Science, Engineering and Technology 24 (December 27, 2022): 143–61. http://dx.doi.org/10.54097/hset.v24i.3906.

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The identification of Chinese herbal medicines is a key issue in the field of traditional Chinese medicine. Based on the characteristics of Chinese herbal medicines, the classification of types, producing areas, and quality can be realized. However, traditional identification methods of Chinese herbal medicines mainly rely on manual identification methods, which requires a lot for identification personnel with low efficiency. To solve this problem, we study the intelligent method of identification of Chinese herbal medicines by using data of infrared spectroscopy characteristic. To solve this problem, this paper studies the classification of spectral characteristic data of Chinese herbal medicines from unsupervised and supervised learning. Firstly, an improved K-means clustering algorithm based on Gaussian distribution model is established for unsupervised spectral classification of Chinese herbal medicines. This method “over-classifies” the sample data by K-means clustering algorithm, and further classifies the data by Gaussian mixture model, thus realizing unsupervised classification of Chinese herbal medicines. Secondly, aiming at the supervised classification and recognition of Chinese herbal medicines, an improved discriminant analysis classification method based on Gaussian distribution is established to identify different kinds and producing areas of Chinese herbal medicines. Finally, we test our method on two sets of data with and without tagged information, with Chinese herbal medicines in two data sets identified respectively. The experimental results fully verify the effectiveness of the method, especially in the supervised identification of Chinese herbal medicines. We have proved the effectiveness of our designed model through the comparison of various methods and extensive tests.
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5

Zhu, You-Ping, and Herman J. Woerdenbag. "Traditional Chinese herbal medicine." Pharmacy World & Science 17, no. 4 (July 1995): 103–12. http://dx.doi.org/10.1007/bf01872386.

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6

Ernst, E. "Chinese Herbal Medicines." Focus on Alternative and Complementary Therapies 7, no. 2 (June 14, 2010): 207–8. http://dx.doi.org/10.1111/j.2042-7166.2002.tb05483.x.

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7

Adams, A. K. "Chinese herbal medicines." Anaesthesia 58, no. 4 (March 18, 2003): 385. http://dx.doi.org/10.1046/j.1365-2044.2003.03095_2.x.

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8

Adams, Aileen K. "Chinese Herbal Medicines." Journal of Medical Biography 11, no. 2 (May 2003): 124. http://dx.doi.org/10.1177/096777200301100219.

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9

Liu, Shihui, Toshihiko Matsuo, Chie Matsuo, and Takumi Abe. "Traditional Chinese Medicines and Prescriptions Brought from China to Japan by a Monk (Jianzhen, Japanese: Ganjin): A Historical Review." Compounds 2, no. 4 (October 18, 2022): 267–84. http://dx.doi.org/10.3390/compounds2040022.

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(1) Background: Japanese Kampo medicine has its origin in ancient Chinese medicine. In 742, a Tang Dynasty monk named Jianzhen (Ganjin) was invited by Japanese clerics to visit Japan and teach commandments in Buddhism. Because of the dangers of the voyage and also other obstacles, he took 11 years to reach Japan on the sixth voyage and he was blind when he arrived in Japan. He was the first person in China to go to Japan to establish the Buddhism commandments, and he was also the first person in Japan to directly teach traditional Chinese medicine. Until now, there have been few reports in English about the details of the Chinese herbal medicines he brought to Japan, including the types of herbal medicines, pharmacological activities, and formulations. In the review, we systematically and comprehensively summarized Jianzhen’s life from the standpoint of his medical and pharmaceutical knowledge and the types and pharmacological activities of Chinese herbal medicines and prescriptions that were brought to Japan by Jianzhen; (2) Methods: A review was made on the relevant literature written by Chinese, Japanese, and English languages regarding the medical and pharmacological knowledge of Jianzhen, the 36 Chinese herbal medicines brought to Japan by Jianzhen, and the pharmacological and therapeutic effects of these 36 herbal medicines, as well as their formulations; (3) Results: The review of the literature proved that Jianzhen’s prescriptions served as a basis for current herbal medicines (Kampo) in Japan. In the process of the literature search, we found a book entitled Jianshangren (Holy Priest Jianzhen)’s Secret Prescription, which recorded the complete prescription of the 36 traditional Chinese medicines Jianzhen brought to Japan; (4) Conclusions: Jianzhen is one of the ancestors of traditional Chinese medicine/Kampo medicine, and he brought traditional Chinese medicine and medical books to Japan for patients. He made important contributions to the development of traditional Chinese medicine in Japan.
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10

Yu, Ao, David Adelson, and David Mills. "Chinese Herbal Medicine Versus Other Interventions in the Treatment of Type 2 Diabetes." Journal of Evidence-Based Integrative Medicine 23 (January 1, 2018): 2515690X1878151. http://dx.doi.org/10.1177/2515690x18781519.

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Diabetes affects 422 million people and directly caused 4.9 million deaths according to the global report on diabetes in 2014. Type 2 diabetes accounts for 90% of people with diabetes around the world. Chinese herbal medicine treatment for diabetes has more than 2000-year history in China. An increasing number of people around the world are trying to manage type 2 diabetes with Chinese herbal medicine. However, there is a lack of evidence to decide if Chinese herbal medicine is effective and safe when compared with other interventions for the treatment of type 2 diabetes We identified 58 randomized controlled trials involving 6637 participants with type 2 diabetes with trial periods lasting from 8 weeks to 1 year (average 12 weeks). We extracted data following a predefined hierarchy. A total of 132 different Chinese herbal medicines were examined. We included studies comparing Chinese herbal medicine with other interventions and excluded trials that did not satisfy the inclusion criteria. We evaluated primary outcomes of trials in accordance with the Cochrane Handbook for Systematic Reviews of Intervention. Fifty-six out of 58 studies reported evidence that Chinese herbal medicines were effective at controlling blood sugar, insulin resistance, and traditional Chinese medicine clinical symptoms for patients with type 2 diabetes. And outcome variables are summarized. However, the evidence is limited because of the quality of the studies. Well-designed long-term studies with large samples and multiple centers as well as standardization and quality control will be required to determine if Chinese herbal medicine treatment is effective and safe for type 2 diabetes.
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11

Han, Ke, Miao Wang, Lei Zhang, and Chunyu Wang. "Application of Molecular Methods in the Identification of Ingredients in Chinese Herbal Medicines." Molecules 23, no. 10 (October 22, 2018): 2728. http://dx.doi.org/10.3390/molecules23102728.

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There are several kinds of Chinese herbal medicines originating from diverse sources. However, the rapid taxonomic identification of large quantities of Chinese herbal medicines is difficult using traditional methods, and the process of identification itself is prone to error. Therefore, the traditional methods of Chinese herbal medicine identification must meet higher standards of accuracy. With the rapid development of bioinformatics, methods relying on bioinformatics strategies offer advantages with respect to the speed and accuracy of the identification of Chinese herbal medicine ingredients. This article reviews the applicability and limitations of biochip and DNA barcoding technology in the identification of Chinese herbal medicines. Furthermore, the future development of the two technologies of interest is discussed.
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12

Zhu, Ying Li, and Ling Qin Xie. "Application of Wireless Sensor Network in the Monitoring System for Valuable Chinese Herbal Medicine Growth." Applied Mechanics and Materials 475-476 (December 2013): 442–45. http://dx.doi.org/10.4028/www.scientific.net/amm.475-476.442.

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Chinese herbal medicine with no side effects can help people resist disease and keep healthy, due to predatory excavation, and heavy deforestation, the destruction ecological environment, lots of the precious Chinese herbal medicines are on the edge of exhaustion. In order to protect Chinese herbal medicines and do artificial cultivation, the paper presents a real-time monitoring system based wireless sensor network. The system gives the hardware design of wireless sensor node and software implementations. The nodes are mainly responsible for collecting and transporting the environment parameters of the Chinese herbal medicine including temperature, humidity and light intensity and so on, and send the data through the GPRS module to the remote monitoring center. The system can make the artificial cultivation of the medicines more modern, scientific and objective.
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13

Zhao, Xiaoqi, Jie Wang, Lei Wang, Shiming Ren, Zheng Hu, and Yamei Wang. "Preparation and properties of nano-TiO2-Chinese herbal medicine composite wood." BioResources 16, no. 2 (May 2, 2021): 4252–74. http://dx.doi.org/10.15376/biores.16.2.4252-4274.

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The sol-gel method was used to make nano-TiO2 and five Chinese herbal medicines of Sophora flavescens Alt., Hypericum perforatum L., Cnidium monnieri (L.) Cuss., Kochia scoparia (L.), and Zanthoxylum bungeanum Maxim. to prepare five kinds of nano-TiO2-Chinese herbal medicine composite anti-degradative wood. Populus tomentosa Carr was chosen as the wood sample. Indoor decay resistance test results showed that the resistance to weight gain and decay of nano-TiO2-Chinese herbal medicine composite anti-degradative wood noticeably increased compared with either Chinese herbal medicine modified wood or nano-TiO2 modified wood, reaching a strong decay resistance level. The results of the anti-loss test showed that the magnitude of loss of wood samples treated with nano-TiO2 and Chinese herbal medicine was noticeably reduced compared with that with just Chinese herbal medicine. It was found by scanning electron microscopy that the nano-TiO2 particles and the Chinese herbal medicine enter the wood cell cavity, and the wood vessels and pits were the main permeation channels. Fourier transform infrared analysis results showed that nano-TiO2 could not only enter the wood interior, and associate with wood components through physical adsorption to form hydrogen bonds, but also through the carboxyl groups in cellulose and hemicellulose, or the phenolic hydroxyl group in lignin, forming a coordinated chemical bond to fix it in the wood component.
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14

Rathbone, John, Lan Zhang, Mingming Zhang, Jun Xia, Xiehe Liu, Yanchun Yang, and Clive Elliott Adams. "Chinese herbal medicine for schizophrenia." British Journal of Psychiatry 190, no. 5 (May 2007): 379–84. http://dx.doi.org/10.1192/bjp.bp.106.026880.

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BackgroundChinese herbal medicine has been used to treat millions of people with schizophrenia for thousands of years.AimsTo evaluate Chinese herbal medicine as a treatment for schizophrenia.MethodA systematic review of randomised controlled trials (RCTs).ResultsSeven trials were included. Most studies evaluated Chinese herbal medicine in combination with Western antipsychotic drugs; in these trials results tended to favour combination treatment compared with antipsychotic alone (Clinical Global Impression ‘not improved/worse’ n= 123, RR=0.19, 95% CI 0.1-0.6, NNT=6,95% CI 5–11; n=109, Brief Psychiatric Rating Scale ‘not improved/worse’ RR=0.78,95% CI 0.5-1.2; n=109, Scale for the Assessment of Negative Symptoms ‘not improved/worse’ RR=0.87,95% CI 0.7-1.2; n= 109, Scale for the Assessment of Positive Symptoms ‘not improved/worse’ RR=0.69,95% CI 0.5-1.0, NNT=6 95% CI 4-162). Medium-term study attrition was significantly less for people allocated the herbal/antipsychotic mix (n=897, four RCTs, RR=0.34,95% CI 0.2–0.7, NNT=23,95% CI 18-43).ConclusionsResults suggest that combining Chinese herbal medicine with antipsychotics is beneficial.
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15

He, Caihong, Peng Fu, Kexin Zhang, Qing Xia, Yunmei Yang, and Liangzhen Xie. "Chinese herbal medicine for dyslipidemia." Medicine 97, no. 44 (November 2018): e13048. http://dx.doi.org/10.1097/md.0000000000013048.

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Wong, H. "Chinese Herbal Medicine and Allergy." Allergy & Clinical Immunology International - Journal of the World Allergy Organization 13, no. 5 (2001): 0192–96. http://dx.doi.org/10.1027/0838-1925.13.5.192.

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17

Hon, Kam Lun, Chung Mo Chow, and Ting Fan Leung. "Long live Chinese herbal medicine." International Journal of Dermatology 49, no. 11 (October 22, 2010): 1303–5. http://dx.doi.org/10.1111/j.1365-4632.2009.04385.x.

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18

Zhang, Jie, Qianying Yu, Li Peng, Wenxia Lin, Yuesi Qin, Ying He, Jing Guo, Min Xiao, and Mingling Chen. "Chinese herbal medicine for psoriasis." Medicine 99, no. 39 (September 25, 2020): e22400. http://dx.doi.org/10.1097/md.0000000000022400.

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19

Chen, Shun-Sheng, Dean-Chuan Wang, Tsan-Ju Chen, and Shu-Ling Yang. "Administration of Chinese Herbal Medicines Facilitates the Locomotor Activity in Dystrophin-Deficient Mice." American Journal of Chinese Medicine 29, no. 02 (January 2001): 281–92. http://dx.doi.org/10.1142/s0192415x01000307.

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The purpose of this study was to access the effects of chinese herbal medicines on Duchenne muscular dystrophy (DMD). We use dystrophin-deficient mice (mdx), an animal model of DMD, to evaluate the effect of chinese herbal medicines on locomotor activity. The consumption of water for each mouse was controlled during the three-month experimental session. Each mouse was allowed to drink 3 ml water with or without herbal medicines daily for three months. The estimated intake of chinese herbal medicine in adult mdx mouse with 30 g weight is 100 mg/kg per day, close to a dose used in human. The locomotor activity of the mdx mice was measured every month. Monitoring the locomotor activity of mdx mice after three-month administration of chinese herbal medicines, the results showed that Liu-Wei-Di-Huang-Wan (LDW) and San-Lin-Pai-Tsu-San (SPS) can facilitate locomotor activity with the parameters of horizontal activity, total distance, number of movements, movement time, vertical activity, number of vertical movements, vertical movement time, stereotypy, number of stereotyped movements, and stereotyped movement time. These results suggest that either LDW or SPS can act as a potent herbal medicine for the pharmacological treatment of DMD patients.
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Chou, Shu-Huey, Chun-Che Huang, Ching-Heng Lin, Kun-Chang Wu, and Pei-Jung Chiang. "General Use of Chinese Herbal Products among Female Patients with Mastitis in Taiwan." Evidence-Based Complementary and Alternative Medicine 2022 (March 25, 2022): 1–9. http://dx.doi.org/10.1155/2022/3876240.

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Objectives. Little information is available regarding the use of Chinese herbal medicine to treat mastitis. This study evaluated the prescription patterns of Chinese herbal medicine products in women with mastitis in Taiwan. Design. This is a population-based cross-sectional study. Setting. 8,531 women aged 20–49 years, who received a diagnosis of mastitis between 2004 and 2013, were identified from the Longitudinal Health Insurance Database in Taiwan. We collected data on demographic characteristics, including age, monthly insurance premium, and urbanization level. The ten most Chinese herbal medicines prescribed for mastitis were assessed, including frequency, percentage, average daily dose, and average duration of prescription. Main outcome measures. We analysed the ten most single Chinese herbs and Chinese herbal formulae prescribed for mastitis. Results. Overall, 437 (5.1%) women received Chinese herbal medicine to treat mastitis. Mai Men Dong (Ophiopogon japonicus (Thunb.) Ker Gawl.; 22.3%), Pu Gong Yin (Taraxacum mongolicum Hand.-Mazz.; 7.8%), and Wang Bu Liu Xing (Vaccaria hispanica (Mill.) Rauschert; 3.5%) were three of the most commonly prescribed single Chinese herbs for mastitis. Xian-Fang-Huo-Ming-Yin (18.2%), Jia-Wei-Xiao-Yao-San (9.1%), and Chai-Hu-Shu-Gan-San (8.4%) were three of the most commonly prescribed Chinese herbal formulae. Conclusion. Xian-Fang-Huo-Ming-Yin can clear heat, detoxify body, alleviate swelling, activate blood, and relieve pain. It was the most frequently prescribed Chinese herbal formula in patients with mastitis.
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Chen, Hongdong, Jing Guo, Bing Pang, Linhua Zhao, and Xiaolin Tong. "Application of Herbal Medicines with Bitter Flavor and Cold Property on Treating Diabetes Mellitus." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/529491.

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Diabetes mellitus has been a global pandemic. Traditional Chinese Medicine has been used on diabetes mellitus for thousands of years and the modern Chinese medicine studies have found a curative effect of herbal medicine with bitter flavor and cold property on diabetes. This review will introduce the theory summary of flavor and property in TCM, argument basis, the evidences from clinical trails and animal experiments, the possible antidiabetic mechanisms, and advantages on lowering glucose of herbal medicines with bitter flavor and cold property and take rhizome, Chinese rhubarb, andMomordica charantia, the three herbal medicines with bitter flavor and cold property, as examples to illustrate the exact antidiabetic effect. It is hoped that this review can provide some ideas and inspiration for the treatment of diabetes with herbal medicine.
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Huang, Chia-Yu, Mei-Yao Wu, Yu-Hung Kuo, Sio-Ian Tou, and Hung-Rong Yen. "Chinese Herbal Medicine Is Helpful for Survival Improvement in Patients With Multiple Myeloma in Taiwan: A Nationwide Retrospective Matched-Cohort Study." Integrative Cancer Therapies 19 (January 2020): 153473542094328. http://dx.doi.org/10.1177/1534735420943280.

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Aim of the Study: The purpose of this study is to demonstrate that Chinese herbal medicine is beneficial for survival improvement in patients with multiple myeloma. Materials and Methods: We performed a 1:1 propensity score–matched cohort study to analyze patients with multiple myeloma diagnosed between January 1, 2002, and December 31, 2012, through the Taiwanese National Health Insurance Research Database. Patients who received Chinese herbal medicine therapy from the initial date of diagnosis of multiple myeloma to December 31, 2012, were included in the Chinese herbal medicine group. Patients who were not treated with Chinese herbal medicine during the same interval were categorized in the non-Chinese herbal medicine group. A Cox regression model was used to adjust for sex, age, comorbidities, and drug use. Hazard ratios were also compared between the 2 groups. Results: A total of 312 patients were identified after 1:1 propensity score matching. The patients had similar basic characteristics. A better survival status was found in the Chinese herbal medicine cohort (log-rank test, P < .0001). Finally, 49 patients in the Chinese herbal medicine cohort and 96 patients in the non-Chinese herbal medicine cohort died (adjusted hazard ratio = 0.35, 95% confidence interval = 0.24-0.51). The effect of survival improvement from Chinese herbal medicine in patients with multiple myeloma could be observed when prescriptions had the duration of ≥30 days. Conclusions: Our results showed that patients with multiple myeloma could benefit from Chinese herbal medicine treatment, which could improve the survival rate in Taiwan. The findings offer important ideas for further study.
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Zheng, Yanyan, and Ying Chen. "The Identification of Chinese Herbal Medicine Combination Association Rule Analysis Based on an Improved Apriori Algorithm in Treating Patients with COVID-19 Disease." Journal of Healthcare Engineering 2022 (August 31, 2022): 1–11. http://dx.doi.org/10.1155/2022/6337082.

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In this work, an improved Apriori algorithm is proposed. The main goal is to improve the processing efficiency of the algorithm, and the idea and process of the Apriori algorithm are optimized. The proposed method is compared with the classical association rule algorithm to verify its effectiveness. Traditional Chinese medicine plays a certain role in the prevention and treatment of COVID-19. In order to deeply mine the association rules between Chinese herbal medicines for the prevention and treatment of COVID-19, this improved Apriori algorithm is applied from the retrieved published scientific literature and the guidelines for the prevention and treatment of COVID-19 published all over China. Based on the representation of traditional Chinese medicine data in binary form, the potential core traditional Chinese medicine combinations in the treatment of COVID-19 are identified. The results of association rules of Chinese herbal medicine data obtained from the real database provide an important reference for the analysis of COVID-19 combined treatment of Chinese herbal medicine.
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Su, Xuefeng, Zhuoting Yao, Shengting Li, and He Sun. "Synergism of Chinese Herbal Medicine: Illustrated by Danshen Compound." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–10. http://dx.doi.org/10.1155/2016/7279361.

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The primary therapeutic effects of Chinese herbal medicine (CHM) are based on the properties of each herb and the strategic combination of herbs in formulae. The herbal formulae are constructed according to Chinese medicine theory: the “Traditional Principles for Constructing Chinese Herbal Medicinal Formulae” and the “Principles of Combining Medicinal Substances.” These principles of formulation detail how and why multiple medicinal herbs with different properties are combined together into a single formula. However, the concept of herbal synergism in CHM still remains a mystery due to lack of scientific data and modern assessment methods. The Compound Danshen Formula (CDF) is a validated formula that has been used to treat a variety of diseases for hundreds of years in China and other countries. The CDF will be employed to illustrate the theory and principle of Chinese herbal medicine formulation. The aim of this review is to describe how Chinese herbal medicinal formulae are constructed according to Chinese medicine theory and to illustrate with scientific evidence how Chinese herbs work synergistically within a formula, thereby supporting Chinese medicine theory and practice.
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Zhu, Anming, Shiming Ren, Xueqi Li, Xiaoqi Zhao, Lei Wang, Minzhen Bao, and Yamei Wang. "Study of Antifungal Activity Using Three Chinese Medicine Herbs." Forest Products Journal 71, no. 4 (October 1, 2021): 322–29. http://dx.doi.org/10.13073/fpj-d-21-00027.

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Abstract Chinese medicine herbal extracts are ideal candidates to replace toxic industrial wood preservatives thanks to their antifungal and nontoxic properties. To investigate the antifungal activity of Chinese herbal medicines, in this study, Trametes versicolor fungi were selected as test strains to evaluate the antifungal properties of Fructus Cnidii, Fructus Forsythiae, and Radix Stemonae. The results show that Fructus Cnidii has a strong inhibitory effect against T. versicolor, whereas Fructus Forsythiae and Radix Stemonae have a weak inhibitory effect. The hyphae growth cycle shows that the three studied Chinese herbs disrupt the growth of T. versicolor. Moreover, instead of direct killing, the Chinese herbal medicine demonstrated inhibition ability. Furthermore, the morphological and toxicological evidence shows that Fructus Cnidii affected the expression of proteins or enzymes to achieve the inhibition goal. In sum, this study could provide both primary data and a theoretical foundation for further developing and applying for traditional Chinese medicine as a green type of wood preservative.
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Zhao, Na, Xiaoming Su, Yueyang Wang, Jianguang Chen, and Wenyue Zhuang. "Traditional Chinese Herbal Medicine for Whitening." Natural Product Communications 15, no. 2 (February 2020): 1934578X2090514. http://dx.doi.org/10.1177/1934578x20905148.

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Melanin is the chief pigment responsible for the pigmentation of human skin. Increasing evidence indicates that traditional Chinese drugs with skin-whitening effects are attracting the attention of consumers and researchers because they are perceived to be milder, safer, and healthier than synthetic alternatives. This commentary summarizes the current research on Chinese herbal medicines that inhibit melanin and their biological activities. The findings presented in this study suggest that these traditional Chinese herbal medicines might be potential candidates for novel skin-whitening agents.
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Lu, Ping-Hsun, Chien-Cheng Lai, I.-Hsin Lin, Fu-Ming Tsai, and Po-Hsuan Lu. "Clinical Efficacy and Safety of Chinese Herbal Medicine in the Treatment of Uremic Pruritus: A Meta-Analysis of Randomized Controlled Trials." Pharmaceuticals 15, no. 10 (October 9, 2022): 1239. http://dx.doi.org/10.3390/ph15101239.

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Uremic pruritus is a disturbing and refractory symptom in patients with advanced chronic kidney disease. Chinese herbal medicine has been reported to alleviate uremic pruritus. To investigate the effects of Chinese herbal medicine, we conducted a systematic review and meta-analysis on patients with uremic pruritus. We searched databases (prior to 3 May 2022) for randomized controlled trials on the effects of Chinese herbal medicine in treating uremic pruritus. Our meta-analysis included 3311 patients from 50 randomized controlled trials. In patients with uremic pruritus, adjunctive Chinese herbal medicine significantly improved overall effectiveness (risk ratio 1.29, 95% CI 1.23 to 1.35), quality of life, renal function, reduced pruritus score, and inflammatory biomarkers compared to control groups with hemodialysis alone or with anti-pruritic treatments. Chinese herbal medicine treatment showed a time-dependent tendency in improving the visual analog scale of dialysis patients. Compared to control groups, no significantly higher risk of adverse events in patients taking Chinese herbal medicine (risk ratio 0.60, 95% CI 0.22 to 1.63). Chinese herbal medicine appears to be effective and safe in complementing the treatment of patients with uremic pruritus.
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Santos, Gustavo Carrião, Eduardo Eler, Maria Eduarda Honorato, Nathalia Rocha, Paula Lobo Guimarães, Rafaela Curiele, and Carlos Rocha Olliveira. "Traditional Chinese Herbal Medicine and Corticosteroids in Asthma: A short review." Brazilian Journal of Natural Sciences 4, no. 3 (March 17, 2022): E1522022. http://dx.doi.org/10.31415/bjns.v4i2.152.

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Asthma is a prevalent chronic inflammatory disease that has gold standard treatment with corticosteroids, but these are associated with important long-term side effects. On this basis, Traditional Chinese Medicine contributes with therapeutic techniques such as the herbal Anti-Asthma Herbal Medicine Intervention (ASHMI). In this context, this study aims to evaluate the effectiveness of treatment with ASHMI compared to conventional therapy, considering the need for new therapeutic approaches. An integrative review was performed, according to the PRISMA methodology. Articles published between 2011 and 2021 that related Herbal Medicines of Traditional Chinese Medicine, asthma and corticosteroids were examined. The searches took place in October and November 2021 in the Scopus, PubMed, Web of Science, Google Scholar, and Scielo databases. The selection comprised steps such as: search, pre-selection and inclusion of articles. The results of the herbal medicine and its isolated components were demonstrated, with three studies being clinical trials with humans and four pre-clinical studies. From the results, the efficacy of the herbal medicine and its components compared to corticosteroids were evaluated. It was reported that ASHMI, unlike corticosteroids, does not suppress the hypothalamic-pituitary-adrenal axis and the immune system, having mild adverse effects
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Xu, Lian-Wei, Man Jia, Xue-Jun Cui, Hong-Yong Deng, Sven Schroeder, and Roland Salchow. "Chinese Herbal Medicine for Menopausal Symptoms." Forum on Immunopathological Diseases and Therapeutics 3, no. 1 (2012): 71–89. http://dx.doi.org/10.1615/forumimmundisther.v3.i1.70.

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Jiang, Cui, Zhaodi Wang, Shiqing Yuan, Yong Jiang, and Ying Ye. "Chinese herbal medicine for immune infertility." Medicine 100, no. 5 (February 5, 2021): e24248. http://dx.doi.org/10.1097/md.0000000000024248.

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31

Xiao, B. "Functional targets of Chinese herbal medicine." Journal of Chinese Integrative Medicine 8, no. 12 (December 15, 2010): 1190–94. http://dx.doi.org/10.3736/jcim20101212.

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32

Mukwaya, Emmanuel, Fei Xu, Man-Sau Wong, and Yan Zhang. "Chinese herbal medicine for bone health." Pharmaceutical Biology 52, no. 9 (June 25, 2014): 1223–28. http://dx.doi.org/10.3109/13880209.2014.884606.

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Yanai, Akira. "CHINESE HERBAL MEDICINE AND FLAP SURVIVAL." Plastic and Reconstructive Surgery 111, no. 5 (April 2003): 1780. http://dx.doi.org/10.1097/01.prs.0000060520.86939.68.

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Ling Xu, Li Xing Lao, Adeline Ge, Shan Yu, Jie Li, and Patrick J. Mansky. "Chinese Herbal Medicine for Cancer Pain." Integrative Cancer Therapies 6, no. 3 (September 2007): 208–34. http://dx.doi.org/10.1177/1534735407305705.

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Kam, P. C. A., and S. Liew. "Traditional Chinese herbal medicine and anaesthesia." Anaesthesia 57, no. 11 (October 22, 2002): 1083–89. http://dx.doi.org/10.1046/j.1365-2044.2002.02823.x.

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36

Daniel, Peter T. "A TRAIL to Chinese herbal medicine." Blood 108, no. 12 (December 1, 2006): 3634. http://dx.doi.org/10.1182/blood-2006-09-046458.

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Morabia, Alfredo, and Michael C. Costanza. "Could Chinese herbal medicine be nephrotoxic?" Preventive Medicine 55, no. 2 (August 2012): 85–86. http://dx.doi.org/10.1016/j.ypmed.2012.06.024.

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Wiebrecht, Axel. "Chinese Herbal Medicine. Formulas & Strategies." Deutsche Zeitschrift für Akupunktur 53, no. 1 (2010): 75–76. http://dx.doi.org/10.1016/j.dza.2010.01.016.

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Omer Mohamed, HaiderAli, OsamaMirghani Osman, HusaamHaider Ali, MohammedNasser Asiri, AbdulrhmanAli Hassan, IbrahimMohammed Almangah, AbbasOmer Elkarib, and Ali AbBshabshe. "A complicated chinese herbal medicine nephrotoxicity." Saudi Journal of Kidney Diseases and Transplantation 31, no. 2 (2020): 533. http://dx.doi.org/10.4103/1319-2442.284032.

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Chen, Xiaofei, Yunfen Zhu, Yongkang Yang, Jiqian Xiang, Hongqing Yin, Jin Ma, Dejun Tan, and Rong Li. "PSVI-28 Effects of Chinese herbal medicine and probiotics on the physicochemical properties of chicken." Journal of Animal Science 97, Supplement_3 (December 2019): 209. http://dx.doi.org/10.1093/jas/skz258.429.

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Abstract Objective: In this study, we estimate the effects of probiotics, Chinese herbal medicine and antibiotics on chicken protein, fat, ash, some kind of amino acids and fatty acids, tenderness and other physical and chemical properties. Method: 240 hens were divided into six groups, including blank control group, probiotic group, antibiotic group, Chinese herbal medicine group (Three parallel groups were set in the Chinese herbal medicine group: 0.3%, 0.6% and 1%). Hens were fed on restricted diets for more than 120 days. Collecting six breast samples from each group randomly and assaying those items described in the objective. In this study, we performed some determination methods, such as HPLC, GC, Kjeldahl and Soxhelt Method. Data were collected by Excel and analyzed by SPSS18.0 software. The results were expressed as the mean ± SD. One-way ANOVA followed by Duncan’s test was performed to determine statistical significance. ResultThe results showed that the contents of protein, fat, amino acid and fatty acid in chicken were not different significantly among these groups (P &gt; 0.05). So did the value of shear (P &gt; 0.05). Inosine acid content in 0.6% & 1% Chinese herbal medicine group was increased significantly (P &lt; 0.05). The ash value was decreased significantly in 1% Chinese herbal medicine group (P &lt; 0.05). Significance and Innovation: There are many alternatives of antibiotics in livestock and poultry breeding based on Chinese herbal medicine in China. Our study helps to illustrate the positive effect of Chinese herbal medicine on animal feeding and lay a foundation for the future rational application of Chinese herbal medicine in non-antibiotic feeding. Meanwhile, similar reports have not been found internationally. Conclusion Adding proper amount of Chinese herbal medicine in diet can promote the production of inosine acid and enhance the taste of meat, reduce the ash content similarly.
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Wang, Lixin, Xu Zuo, Zhuoer Ouyang, Ping Qiao, and Fang Wang. "A Systematic Review of Antiaging Effects of 23 Traditional Chinese Medicines." Evidence-Based Complementary and Alternative Medicine 2021 (May 15, 2021): 1–13. http://dx.doi.org/10.1155/2021/5591573.

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Background. Aging is an inevitable stage of body development. At the same time, aging is a major cause of cancer, cardiovascular disease, and neurodegenerative diseases. Chinese herbal medicine is a natural substance that can effectively delay aging and is expected to be developed as antiaging drugs in the future. Aim of the review. This paper reviews the antiaging effects of 23 traditional Chinese herbal medicines or their active components. Materials and methods. We reviewed the literature published in the last five years on Chinese herbal medicines or their active ingredients and their antiaging role obtained through the following databases: PubMed, EMBASE, Scopus, and Web of Science. Results. A total of 2485 papers were found, and 212 papers were screened after removing the duplicates and reading the titles. Twenty-three studies met the requirements of this review and were included. Among these studies, 13 articles used Caenorhabditis elegans as the animal model, and 10 articles used other animal models or cell lines. Conclusion. Chinese herbal medicines or their active components play an antiaging role by regulating genes related to aging through a variety of signaling pathways. Chinese herbal medicines are expected to be developed as antiaging drugs or used in the medical cosmetology industry.
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Guo, Jing, Yabin Gao, Yaoxian Wang, Wei Jing Liu, Jingwei Zhou, and Zhen Wang. "Application of Herbal Medicines with Heat-Clearing Property to Anti-Microinflammation in the Treatment of Diabetic Kidney Disease." Evidence-Based Complementary and Alternative Medicine 2019 (June 2, 2019): 1–6. http://dx.doi.org/10.1155/2019/6174350.

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Diabetic kidney disease (DKD) is a global pandemic, and microinflammation has been reported as an important pathogenic factor of DKD. Traditional Chinese Medicine (TCM) has been used in the treatment of DKD for thousands of years, and modern Chinese medicine studies have found that herbal medicines with heat-clearing property have a curative anti-inflammation effect in DKD. This article reviews the new clinical and experimental progress made in herbal medicines with heat-clearing property, in the treatment of DKD, as well as their safety aspects.
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Cai, Bin, Ai-guo Zhang, Xian Zhang, Wen-jie Ge, Guo-da Dai, Xiang-ling Tan, Gopaul Roodrajeetsing, and Jian-ping Cai. "Promoting Effects on Proliferation and Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells by Four “Kidney-Tonifying” Traditional Chinese Herbs." BioMed Research International 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/792161.

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Traditional Chinese medicine can promote the proliferation of bone marrow-derived mesenchymal stem cells (BMSCs). We chose four “Kidney-tonifying” Chinese herbal medicines, Radix Astragali, Salvia, Herba Epimedii, and Saussurea Involucrata, to evaluate whether they had positive effects on the proliferation of BMSCs and TGF-β1-induced chondrogenic differentiation of BMSCs. The four Chinese herbal medicines were intragastrically administered to Sprague-Dawley rats, respectively, to prepare drug-containing serums of corresponding Chinese herbs. BMSCs were isolated, cultured, and exposed to culture solution containing 1%, 5%, 10%, and 15% (v/v) Radix Astragali-, Salvia-, Herba Epimedii-, and Saussurea Involucrata-containing serum, respectively. TGF-β1-induced BMSCs were addressed in the same manner. Collagen type II protein was assessed by immunofluorescence methods. To assess whether the drug-containing serums had positive effects on the proliferation of BMSCs and TGF-β1-induced BMSCs, MTT method was assessed. The proliferation of BMSCs was significantly enhanced when exposed to culture solutions containing 1% and 5% Radix Astragali-, 1% and 5% Salvia-, 5% Herba Epimedii-, and 1%, 5%, and 10% Saussurea Involucrata-containing serum. The proliferation of TGF-β1-induced BMSCs was significantly enhanced when exposed to 1%, 5%, and 15% Radix Astragali-, 10% and 15% Salvia-, 5%, and 15% Herba Epimedii-, and 1%, 5%, and 10% Saussurea Involucrata-containing serum.
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Guo, De-an, Wenlong Wei, Changliang Yao, Jianqing Zhang, and Qirui Bi. "Chinese herbal medicines with beneficial effects." Frigid Zone Medicine 1, no. 2 (December 1, 2021): 79–83. http://dx.doi.org/10.2478/fzm-2021-0010.

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Abstract Among the vast resources of traditional Chinese medicine (TCM) herbal species, only a handful of Chinese herbs are growing in frigid regions or extreme environment but they have a unique property. The most recognizable TCM herb falling in this category is Panax ginseng, which is widely considered the representative tonic herb with oceans of beneficial effects on human health. In this article, we will introduce several typical Chinese herbal medicines with beneficial effects aiming to arouse broader attention from the scientific community to expand the exploration and exploitation on this for their potential applications to meet the increasingly demanding medical needs.
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Luo, Yun, Chong-Zhi Wang, Richard Sawadogo, Ting Tan, and Chun-Su Yuan. "Effects of Herbal Medicines on Pain Management." American Journal of Chinese Medicine 48, no. 01 (January 2020): 1–16. http://dx.doi.org/10.1142/s0192415x20500019.

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Pain is an unpleasant sensory and emotional experience in many diseases and is often caused by intense or damaging stimuli. Pain negatively affects the quality of life and increases high health expenditures. Drugs with analgesic properties are commonly used to relieve pain, but these Western medications could be overwhelmed by side effects including tolerance and addiction. Herbal medicines may provide alternative measures for pain management. In this review paper, after introduction of Chinese medicine theory and treatment modality, emphasis is placed on the application of Chinese herbs and herbal formulations in pain management. Three of the most commonly used herbs, i.e., Corydalis yanhusuo, Ligusticum chuanxiong, and Aconitum carmichaeli, are reviewed. Subsequently, using this ancient medical remedy, Chinese herbal formulation in treating common medical conditions associated with pain, such as headache/migraine, chest pain, abdominal pain, low back pain, neuropathic pain, osteoarthritis, and cancer pain, is presented. Chinese herbal medicines could be considered as a complementary and integrative approach in the modern armamentarium in combating pain.
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Shahrajabian, Mohamad Hesam, Wenli Sun, and Qi Cheng. "The influence of traditional Iranian and Chinese medicine on western and islamic countries." Asian Journal of Medical and Biological Research 5, no. 2 (August 4, 2019): 94–99. http://dx.doi.org/10.3329/ajmbr.v5i2.42490.

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Traditional Chinese and Iranian medicine are ancient medical and health care systems that still forms an important part of diagnosis and treatment systems in Iran, China and other parts of the world. The integration of these two systems and modern biomedicine is also an important issue. Iranian and Chinese traditional medicines recommended for health promotion and well-being. Chinese herbal drugs have been described by medieval Muslim medical scholars such as Tabari, Rhazes, Haly Abbas, Avicenna and Jurjani (1137 CE). Traditional Chinese and Iranian medicine play an important role in sustainable agriculture and food systems, it also offers a holistic approach to prevent diseases while making appropriate use of organic and herbal products especially growth by small-scale family farmers. Both Iranian and Chinese traditional medicines may help to balance temperature, and both can be health prevention and preservation. Traditional healing practices consist of Islamic religious text based practices, Islamic worship practices and folk healing practices, Islamic religious text based practices are included spiritual healing, medicinal herbs, applied therapy and dietary prescriptions. At present, herbal medications or related products in the global market are derived from Chinese herbs, Indian herbs, Iranian herbs, Arabic herbs, and Western herbs. Herbal remedies may also be classified into three categories, namely, modern herbs, theoretical herbs, and empirical herbs, in accordance with their nature/characteristics and the nature of current usage. Traditional Chinese Asian J. Med. Biol. Res. June 2019, 5(2): 94-99
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Liu, Qing, Jiqiang Li, Jing Wang, Jianping Li, Joseph S. Janicki, and Daping Fan. "Effects and Mechanisms of Chinese Herbal Medicine in Ameliorating Myocardial Ischemia-Reperfusion Injury." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–14. http://dx.doi.org/10.1155/2013/925625.

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Myocardial ischemia-reperfusion (MIR) injury is a major contributor to the morbidity and mortality associated with coronary artery disease, which accounts for approximately 450,000 deaths a year in the United States alone. Chinese herbal medicine, especially combined herbal formulations, has been widely used in traditional Chinese medicine for the treatment of myocardial infarction for hundreds of years. While the efficacy of Chinese herbal medicine is well documented, the underlying molecular mechanisms remain elusive. In this review, we highlight recent studies which are focused on elucidating the cellular and molecular mechanisms using extracted compounds, single herbs, or herbal formulations in experimental settings. These studies represent recent efforts to bridge the gap between the enigma of ancient Chinese herbal medicine and the concepts of modern cell and molecular biology in the treatment of myocardial infarction.
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Tong, Xiao-Lin, Liu Dong, Liang Chen, and Zhong Zhen. "Treatment of Diabetes Using Traditional Chinese Medicine: Past, Present and Future." American Journal of Chinese Medicine 40, no. 05 (January 2012): 877–86. http://dx.doi.org/10.1142/s0192415x12500656.

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Diabetes is a major medical problem that imperils public health. Over two thousand years ago, Traditional Chinese Medicine (TCM) called diabetes-related symptoms "Xiaoke" disease. In ancient China, TCM and Chinese herbal medicines were used widely in treating Xiaoke and abundant experience has been accumulated. This article discusses the TCM theory on diabetes and its achievements in the prevention and treatment of diabetes in the past. Using Chinese herbal medicine, recent progress in diabetes therapeutics, including data from clinical trials, are presented. Mechanistic studies from basic research are discussed. Yin-yang balance and a holistic approach of TCM may complement diabetes treatment in Western medicine. With continuous efforts, TCM could play a more important role in fighting this disease.
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Yamakage, Michiaki, Jun-Ichi Hattori, Jun-Ichi Satoh, and Akiyoshi Namiki. "Effects of the Chinese Herbal Medicines Bupleuri radix, Ginseng radix, and Zingiberis rhizoma on Lymphatic Vessel Activity in Rats." American Journal of Chinese Medicine 34, no. 06 (January 2006): 1063–68. http://dx.doi.org/10.1142/s0192415x06004521.

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The aim of the present study was to determine the effects of the Chinese herbal medicines Bupleuri radix, Ginseng radix and Zingiberis rhizoma on spontaneous lymphatic vessel activity. The effect of each herbal medicine on in vivo lymphatic flow was examined by injection of dye into the femoral regions of rats after feeding with the herbal medicines. In an in vitro study, spontaneous changes in diameter of the rat thoracic duct were monitored, and each segment was exposed to each herbal medicine. In the in vivo study, 100% of the right iliac lymphatic node were positively stained in the herbal medicine group, whereas only 40% of the node were positively stained in the control group. In the in vitro study, Bupleuri radix and Ginseng radix increased the amplitude of spontaneous activity of lymphatic vessels in a concentration-dependent manner with or without L-NAME, an NO synthase inhibitor. The results indicated that the herbal medicines Bupleuri radix and Ginseng radix activated spontaneous lymphatic vasomotion and lymph flow, and the mechanisms of this effect seem to be independent of endothelial cells.
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Wang, Ya Mei, Xi Ming Wang, and Xue Qi Li. "Maybe Absolutely Green - with Chinese Traditional Medicine as Wood Preservative." Advanced Materials Research 239-242 (May 2011): 650–53. http://dx.doi.org/10.4028/www.scientific.net/amr.239-242.650.

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An important way of conservation and protection of forest resources is wood preservative treatment. Currently, chemical preservatives are always used in the wood preservative treatment. Therefore, preservatives security has become an important environmental issue. This study focuses on national wood preservation, which workers are committed on. Many studies have been directed to look for new preservatives that are harmless to humans, animals and environment. Chinese herbal medicine as a wood preservative is selected for the environmental pollution problems of inorganic preservatives. In this paper, according to the application of traditional Chinese medicine, the nature of wood preservative and a preliminary study by the relevant trial, the theory of Chinese herbal medicine wood preservative is proposed. The results showed that Chinese herbal medicine can be used as wood preservatives. Finally, the paper puts forward the potential abilities of Chinese herbal medicine as wood preservatives.
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