Academic literature on the topic 'Chitooligosaccharides (COS)'

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Journal articles on the topic "Chitooligosaccharides (COS)"

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Le, Xuan Minh, Khanh Duy Nguyen, Khoa Dang Tran, Tuan Quoc Tran, and Nghiep Dai Ngo. "Inhitive ability collagenase of N-(cinnamyl) chitooligosaccharide derivative." Science and Technology Development Journal 20, K3 (2017): 83–91. http://dx.doi.org/10.32508/stdj.v20ik3.1096.

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Chitooligosaccharides (COS) with molecular weight 4633 Da and 84.67% of deacetylation were synthesized by hydrolysis of chitosan by cellulase at room temperature (33 ± 1 ° C). This COS, then, were chemically modified by grafting cinnamaldehyde at amino groups on the COS. Derivatives of N- (cinnamyl) chitooligosaccharides (CCOS) synthesized with 50.64% of yield and 72.22% of extent of substitution had inhibitory activity enzyme collagenase (a group of matrix metalloproteinases, enzyme family related to metastatic ability of cancer). Compared with the positive control, 58.23% of the effective to
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Marmouzi, Ilias, Shahira M. Ezzat, Maha M. Salama, et al. "Recent Updates in Pharmacological Properties of Chitooligosaccharides." BioMed Research International 2019 (October 31, 2019): 1–16. http://dx.doi.org/10.1155/2019/4568039.

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Chemical structures derived from marine foods are highly diverse and pharmacologically promising. In particular, chitooligosaccharides (COS) present a safe pharmacokinetic profile and a great source of new bioactive polymers. This review describes the antioxidant, anti-inflammatory, and antidiabetic properties of COS from recent publications. Thus, COS constitute an effective agent against oxidative stress, cellular damage, and inflammatory pathogenesis. The mechanisms of action and targeted therapeutic pathways of COS are summarized and discussed. COS may act as antioxidants via their radical
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Ling, Meixi, Jianghua Li, Guocheng Du, and Long Liu. "Metabolic engineering for the production of chitooligosaccharides: advances and perspectives." Emerging Topics in Life Sciences 2, no. 3 (2018): 377–88. http://dx.doi.org/10.1042/etls20180009.

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Chitin oligosaccharides (CTOs) and its related compounds chitosan oligosaccharides (CSOs), collectively known as chitooligosaccharides (COs), exhibit numerous biological activities in applications in the nutraceutical, cosmetics, agriculture, and pharmaceutical industries. COs are currently produced by acid hydrolysis of chitin or chitosan, or enzymatic techniques with uncontrollable polymerization. Microbial fermentation by recombinant Escherichia coli, as an alternative method for the production of COs, shows new potential because it can produce a well-defined COs mixture and is an environme
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Deng, Jun-Jin, Zong-Qiu Li, Ze-Quan Mo, et al. "Immunomodulatory Effects of N-Acetyl Chitooligosaccharides on RAW264.7 Macrophages." Marine Drugs 18, no. 8 (2020): 421. http://dx.doi.org/10.3390/md18080421.

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The ongoing development of new production methods may lead to the commercialization of N-acetyl chitooligosaccharides (NACOS), such as chitosan oligosaccharides (COS). The bioactivity of NACOS, although not well detailed, differs from that of COS, as they have more acetyl groups than COS. We used two enzymatically produced NACOS with different molecular compositions and six NACOS (NACOS1–6) with a single degree of polymerization to verify their immunomodulatory effects on the RAW264.7 macrophage cell line. We aimed to identify any differences between COS and various NACOS with a single degree
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Jing, Bolin, Gong Cheng, Jianjun Li, Zhuo A. Wang, and Yuguang Du. "Inhibition of Liver Tumor Cell Metastasis by Partially Acetylated Chitosan Oligosaccharide on A Tumor-Vessel Microsystem." Marine Drugs 17, no. 7 (2019): 415. http://dx.doi.org/10.3390/md17070415.

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Chitooligosaccharides (COS), the only cationic oligosaccharide in nature, have been demonstrated to have anti-tumor activity. However, the inhibitory effects of COS on different stages of tumor metastasis are still unknown, and it is not clear what stage(s) of tumor metastasis COS targeted. To study the inhibitory effects of a new partially acetylated chitooligosaccharide (paCOS) with fraction of acetylation (FA) 0.46 on each phase of liver cancer cell metastasis, a dynamic tumor-vessel microsystem undergoing physiological flow was leveraged. paCOS (FA = 0.46) significantly inhibited prolifera
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Zhou, Jiachun, Qiao Chen, Yang Zhang, et al. "Chitooligosaccharides enhance cold tolerance by repairing photodamaged PS II in rice." Journal of Agricultural Science 156, no. 7 (2018): 888–99. http://dx.doi.org/10.1017/s0021859618000862.

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AbstractChitooligosaccharides (COS) are multi-functional foods and nutrients and environmentally friendly biological abiotic-resistance inducing agents for plants. In the current study, the effects and possible mechanisms of COS on improving the cold resistance of rice (II YOU 1259) seedlings were investigated. Compared with the control, a COS pre-soaking treatment enhanced photosynthesis, reduced oxidation damage and led to accumulation of more osmotic regulation substances under chilling treatment. In addition, a novel Deg/HtrA family serine endopeptidase (DegQ) gene, related to COS enhanced
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Hoai, Bui Van, Ngo Dai Nghiep, Dao An Quang, and Nguyen Thi Nam Phuong. "Research antioxidant activity of chitooligosacchride by UV-VIS absorption spectrocopy." ENGINEERING AND TECHNOLOGY 8, no. 1 (2020): 75–81. http://dx.doi.org/10.46223/hcmcoujs.tech.en.8.1.339.2018.

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Chitosan with 80% degree of deacetylation was hydrolyzed by cellulase of Trichoderma viride to prepare chitooligosaccharides (COSs) by the fractionation of the COSs with ultrafiltration membrane. The antioxidant
 activities of the COSs were clarified in this study by reducing power and free radical scavenging ability assay by UV-VIS absorption spectrum. The results show that the COS 1 (10,000-5,000 Da), COS 2 (5,000-3,000 Da), COS 3 (3,000-1,000 Da) and COS 4 (less than1,000 Da) segments have antioxidant properties.The antioxidant activitives of the COSs increased with the increment of co
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Malkov, Nikita, Judith Fliegmann, Charles Rosenberg, et al. "Molecular basis of lipo-chitooligosaccharide recognition by the lysin motif receptor-like kinase LYR3 in legumes." Biochemical Journal 473, no. 10 (2016): 1369–78. http://dx.doi.org/10.1042/bcj20160073.

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LYR3 [LysM (lysin motif) receptor-like kinase 3] of Medicago truncatula is a high-affinity binding protein for symbiotic LCO (lipo-chitooligosaccharide) signals, produced by rhizobia bacteria and arbuscular mycorrhizal fungi. The present study shows that LYR3 from several other legumes, but not from two Lupinus species which are incapable of forming the mycorrhizal symbiosis, bind LCOs with high affinity and discriminate them from COs (chitooligosaccharides). The biodiversity of these proteins and the lack of binding to the Lupinus proteins were used to identify features required for high-affi
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Wang, Qiutong, Yajie Jiang, Xuegang Luo, et al. "Chitooligosaccharides Modulate Glucose-Lipid Metabolism by Suppressing SMYD3 Pathways and Regulating Gut Microflora." Marine Drugs 18, no. 1 (2020): 69. http://dx.doi.org/10.3390/md18010069.

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Chitooligosaccharides (COS) have a variety of biological activities due to their positively charged amino groups. Studies have shown that COS have antidiabetic effects, but their molecular mechanism has not been fully elucidated. The present study confirmed that COS can reduce hyperglycemia and hyperlipidemia, prevent obesity, and enhance histological changes in the livers of mice with type 2 diabetes mellitus (T2DM). Additionally, treatment with COS can modulate the composition of the gut microbiota in the colon by altering the abundance of Firmicutes, Bacteroidetes, and Proteobacteria. Furth
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Thomas, Noel Vinay, Jayachandran Venkatesan, Panchanathan Manivasagan, and Se-Kwon Kim. "Production and Biological Activities of Chitooligosaccharides (COS)—An Overview." Journal of Chitin and Chitosan Science 3, no. 1 (2015): 1–10. http://dx.doi.org/10.1166/jcc.2015.1084.

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Dissertations / Theses on the topic "Chitooligosaccharides (COS)"

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Moussa, Amani. "Synthèse et caractérisation d'oligomères de chitosane pour applications biomédicales." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE1120.

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Les chitooligosaccharides (COS) présentent des propriétés biologiques intéressantes telles que l'activité antimicrobienne, antifongique et antitumorale. Dans ce travail, nous avons utilisé les COS pour des applications très diverses, telles que l'ingénierie des cellules neuronales (blocage de la formation du réseau périneuronal), la complexation des cations Fe2+ et Fe3+ pour la synthèse de particules supermagnatiques et enfin pour le développement de conjugués fonctionnels à base de COS. Dans le cadre de ces études en partenariat, nous avons travaillé sur l'élaboration de chitooligosaccharides
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