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1

Li, Bao Qiang, Yan Ming Huang, Yong Liang Wang, and Yu Zhou. "Mineralization of Bone-Like Apatite in Chitosan Hydrogel." Key Engineering Materials 434-435 (March 2010): 605–8. http://dx.doi.org/10.4028/www.scientific.net/kem.434-435.605.

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Polymers with negative charge groups, such as carboxylic or phosphatic groups, were frequently used to induce or promote the apatite deposition. However, chitosan with potentially chelated calcium ions, were ignored. Inspired by layer by layer technology, chitosan hydrogel without any surface modification process was used as framework to mineralize bone-like apatite. XRD and IR results shown that in situ synthesis bone-like apatite, similar to apatite in rib of rabbit, was carbonate ions partially substituted apatite and preferred growth orientation in direction of their c-axis. Bone-like apat
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2

Dewi, Anne Handrini, and Andi Triawan. "The Newly Bone Formation with Carbonate Apatite-Chitosan Bone Substitute in the Rat Tibia." Indonesian Journal of Dental Research 1, no. 3 (2015): 154. http://dx.doi.org/10.22146/theindjdentres.10065.

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Large bone defect still represent a major problem in orthopedics. A tissue engineering approach has been proposed where osteogenic cells, bioceramic scaffolds and growth factors can play in a role to the bone repair. Bone consist a mineral phase such as carbonate apatite and an organic phase such as collagen. Synthetic carbonate apatite ceramics are considered as promising alloplastic materials for bone substitute. Chitin is the organic matrix of the hard parts of exoskeleton of insect, crustacean and present in a small amounts in mushrooms. It is an insoluble, similar to cellulose and compose
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3

Rattanachan, Sirirat, Piyanan Boonphayak, and Charussri Lorprayoon. "Original article. Development of chitosan/nanosized apatite composites for bone cements." Asian Biomedicine 5, no. 4 (2011): 499–506. http://dx.doi.org/10.5372/1905-7415.0504.065.

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Abstract Background: Calcium phosphate cements (CPC) is a promising materials for bone defect repair. Nanosized apatite or calcium orthophosphate has a better bioactivity than coarser crystals. Chitosan is produced commercially from chitin that is the structural element in the exoskeleton of crustaceans such as crabs and shrimp. The mixing of nanosized apatite and chitosan may provide the consistency cement, improving mechanical properties of the set bone cement. Objective: Develop nanosized apatite powder with chitosan for bone composite cement. Materials and method: Nanosized apatite was syn
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Shirosaki, Yuki, Kohei Okamoto, Satoshi Hayakawa, Akiyoshi Osaka, and Takuji Asano. "Preparation of Porous Chitosan-Siloxane Hybrids Coated with Hydroxyapatite Particles." BioMed Research International 2015 (2015): 1–6. http://dx.doi.org/10.1155/2015/392940.

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This paper describes the apatite deposition of chitosan-silicate porous hybrids derived from chitosan andγ-glycidoxypropyltrimethoxysilane (GPTMS) in alkaline phosphate solution. The preparation of porous hybrids with needle-like apatite on their surfaces is described. Following apatite deposition the porous hybrids maintained high porosity. The enzymatic degradation rate was low even after 6 months and the porous hybrids were very flexible and cut easily using surgical scissors.
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Indrani, Decky Jusiana, Bambang Sunendar Purwasasmita, Wisnu Ari Adi, and Jojor Simanjuntak. "Preparation and Characterization of Magnetic Carbonate Apatite/Chitosan/Alginate Composite Scaffold." Materials Science Forum 827 (August 2015): 75–80. http://dx.doi.org/10.4028/www.scientific.net/msf.827.75.

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Treatment for bone cancer has begun to be experimented with ferrimagnetic for magnetic induction hyperthermia. On the other hand, composites of bioceramics and biopolymer have been studied for scaffold as these materials resemble the structure of bone. The current study investigated the magnetization of calcium aluminum ferrite magnetic (CaAl4Fe8O19) incorporated in carbonate apatite, alginate and chitosan, that serves as a scaffold. CaAl4Fe8O19 powder were synthesized using calcium nitrate, aluminium nitrate and ferrous chloride using the sol-gel method. Combining the carbonate apatite/chitos
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6

Moncif, N., E. L. H. Gourri, A. B. A. Elouahli, et al. "Characterization of Bio-composite Apatite/Chitosan Cement and its Antibacterial Activity." Oriental Journal of Chemistry 34, no. 4 (2018): 1765–73. http://dx.doi.org/10.13005/ojc/340408.

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In this work, we report the physico-chemical properties and antibacterial activity of apatite/chitosan composite cements. The biocomposite was prepared by reaction between dihydrated dicalcium phosphate and calcium hydroxide in the presence of chitosan. The characterization of cement was carried out by Infrared Spectroscopy, X-ray diffraction, Transmission Electron Microscopy and X-ray Scanner with computational image processing. The results show that the setting of the paste is due to the formation of a hydrated tri-calcium phosphate that evolves into a hard calcium-apatite. In the presence o
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7

Bao, Lei, Jing Xiao Liu, Fei Shi, et al. "Rapid Biomimetic Deposition of Drug-Loaded Apatite Coatings." Advanced Materials Research 712-715 (June 2013): 439–42. http://dx.doi.org/10.4028/www.scientific.net/amr.712-715.439.

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In order to reduce the postoperative inflammation by the slow release of drugs at the beginning of implanting, drug-loaded apatite coatings and chitosan-apatite composite coatings on the NiTi alloy surface were prepared in the Simulated Body Fluid concentrated by five (5×SBF) under constant bubbling of carbon dioxide gas by biomimetic synthesis method. The composition and surface morphology of the coatings were studied using scanning electron microscopy (SEM) and X-ray diffraction (XRD). Additionally, a bacterial inhibition test was conducted for evaluating the drug slow release effects from t
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8

Rhee, Sang Hoon, Yong Keun Lee, and Bum Soon Lim. "Evaluation of a Chitosan Nano-Hybrid Material Containing Silanol Group and Calcium Salt as a Bioactive Bone Graft." Key Engineering Materials 284-286 (April 2005): 765–68. http://dx.doi.org/10.4028/www.scientific.net/kem.284-286.765.

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A bioactive chitosan-siloxane nano-hybrid material was newly developed and evaluated for the potential application as a bone graft material. The chitosan which can be dissolved in organic solvent was synthesized by the reaction with phtalic anhydride (Ph-Chitosan) and it was then reacted with 3-isocyanatopropyl triethoxysilane (Si-Chitosan) in dimethylformamide. Following this, the Si-Chitosan was hydrolyzed and condensed to yield a hybrid sol-gel material (Si-O-Chitosan). The gelation was carried out for 1 week at ambient condition in a covered Teflon mold with a few pinholes and then dried u
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9

Rattanachan, Sirirat T., Charussri Lorpayoon, and Piyanan Bunpayun. "Chitosan-Crystallized Apatite Composites for Bone Cements: Mechanical Strength and Setting Behavior." Key Engineering Materials 330-332 (February 2007): 839–42. http://dx.doi.org/10.4028/www.scientific.net/kem.330-332.839.

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Crystallized apatite behaved to plaster of Paris was prepared by the chemical method. Apatite powder was mixed with chitosan. In this study, it was also studied the effect of HA seed and sodium hydrogen phosphate as an additive on their mechanical strength, compared with the normal calcium phosphate cements. Setting time of paste cements was determined using Gillmore method. Phases of cement obtained from a crushed cylinder were analyzed using XRD analysis. From the results, chitosan was effective both in increasing mechanical properties and accelerating hardening of the normal bone cements. N
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10

Paluszkiewicz, Czeslawa, Ewa Stodolak-Zych, Wojciech Kwiatek, and Piotr Jelen. "Bioactivity of a Chitosan Based Nanocomposite." Journal of Biomimetics, Biomaterials and Tissue Engineering 10 (May 2011): 95–106. http://dx.doi.org/10.4028/www.scientific.net/jbbte.10.95.

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In this work, experiments to produce a series of nanocomposites based on natural chitosan and nano-clay (MMT) were conducted. Commercially available montmorillonite (MMT) was used as a nanofiller. CS-MMT nanocomposites were prepared using the casting method. Thin nanocomposite foils were neutralized in NaOH solution, then the nanocomposite foils were soaked in simulated body fluid (SBF). Kinetics of crystallization of the apatite structure was observed using PIXE, FTIR-ATR and SEM/EDS techniques. It was shown that high concentrations of calcium and phosphate ions were located inside the nanoco
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11

Galotta, Anna, Öznur Demir, Olivier Marsan, et al. "Apatite/Chitosan Composites Formed by Cold Sintering for Drug Delivery and Bone Tissue Engineering Applications." Nanomaterials 14, no. 5 (2024): 441. http://dx.doi.org/10.3390/nano14050441.

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In the biomedical field, nanocrystalline hydroxyapatite is still one of the most attractive candidates as a bone substitute material due to its analogies with native bone mineral features regarding chemical composition, bioactivity and osteoconductivity. Ion substitution and low crystallinity are also fundamental characteristics of bone apatite, making it metastable, bioresorbable and reactive. In the present work, biomimetic apatite and apatite/chitosan composites were produced by dissolution–precipitation synthesis, using mussel shells as a calcium biogenic source. With an eye on possible bo
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12

Sukhodub, L. F., L. B. Sukhodub, and I. V. Chorna. "Chitosan-apatite composites: synthesis and properties." Biopolymers and Cell 32, no. 2 (2016): 83–97. http://dx.doi.org/10.7124/bc.000910.

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13

Solís, Yaimara, Natalia Davidenko, Raúl G. Carrodeguas, et al. "Preparation, characterization, and in vitro evaluation of nanostructured chitosan/apatite and chitosan/Si-doped apatite composites." Journal of Materials Science 48, no. 2 (2012): 841–49. http://dx.doi.org/10.1007/s10853-012-6804-5.

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14

Corchado-Albelo, Jose L., and Lana Alagha. "Studies on the Enrichment Feasibility of Rare Earth-Bearing Minerals in Mine Tailings." Minerals 13, no. 3 (2023): 301. http://dx.doi.org/10.3390/min13030301.

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This study aimed to investigate the potential of enrichment of rare-earth-bearing minerals in historic mine tailing using the froth flotation process. Characterization studies indicated that tailings contained 11,000 ppm of rare earth elements (REEs). The major mineral in the tailings was apatite at ~84%, which was associated with iron oxides (~16%). TESCAN’s integrated mineral analysis (TIMA) showed that monazite was the main REE mineral, and 69% of monazite was locked in apatite grains. Characterization studies suggested that the separation of REEs-bearing apatite from iron oxides is possibl
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15

Davidenko, Natalia, Raúl G. Carrodeguas, Carlos Peniche, Yaimara Solís, and Ruth E. Cameron. "Chitosan/apatite composite beads prepared by in situ generation of apatite or Si-apatite nanocrystals." Acta Biomaterialia 6, no. 2 (2010): 466–76. http://dx.doi.org/10.1016/j.actbio.2009.07.029.

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16

Adachi, Yu, Takeshi Yabutsuka, and Shigeomi Takai. "Impartation of apatite-forming ability to chitosan nanofibres by using apatite nuclei." IET Nanobiotechnology 14, no. 8 (2020): 668–72. http://dx.doi.org/10.1049/iet-nbt.2020.0052.

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17

Caridade, Sofia G., Esther G. Merino, Gisela M. Luz, N. M. Alves, and João F. Mano. "Bioactivity and Viscoelastic Characterization in Physiological Simulated Conditions of Chitosan/Bioglass® Composite Membranes." Materials Science Forum 636-637 (January 2010): 26–30. http://dx.doi.org/10.4028/www.scientific.net/msf.636-637.26.

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A number of combinations of biodegradable polymers and bioactive ceramics have been used for orthopaedic applications including in hard tissue regeneration. Ideally, composites aimed to be used in orthopaedic applications should combine adequate mechanical properties and bioactivity. Chitosan (CTS) has been widely used for biomedical applications, namely in tissue regeneration or drug delivery. In this sense, membranes of chitosan and chitosan with Bioglass® (BG) were prepared by solvent casting and characterised using Scanning Electron Microscopy. In vitro bioactivity tests were performed in
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18

Charlena, Alif Aryan Khofiyatuzziyadah, Akhiruddin, and Purwantiningsih. "Synthesis and Antibacterial Properties of Fluorapatite and FAp-ZnO-Chitosan Composite as Dental Implant Materials." Science and Technology Indonesia 10, no. 2 (2025): 562–73. https://doi.org/10.26554/sti.2025.10.2.562-573.

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Regenerative biomaterials research has continued to grow in recent decades, one of which is dental implants. The material that can be used is fluorapatite (FAp), as it is a significant element of human bones and teeth. FAp has better chemical and thermal stability than other apatite materials. However, FAp has low antibacterial properties, so it needs to be composited with other antibacterial materials, such as zinc oxide (ZnO) and chitosan. In addition, chitosan was also added to stabilize FAp and ZnO an effort to increase antibacterial and in vitro bioactivity in apatite formation. Therefore
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19

LI, BAOQIANG, YANQUAN HUANG, YONGLIANG WANG, and DECHANG JIA. "CARBONATED APATITE COATING ON CHITOSAN WITH GRADIENT DISTRIBUTION VIA IONS ASSEMBLY." International Journal of Modern Physics B 24, no. 30 (2010): 5987–94. http://dx.doi.org/10.1142/s0217979210054063.

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Carbonated apatite (CHA) coating on chitosan with gradient distribution was achieved by ions assembly at ambient condition in a short period time. Chitosan hydrogel can directly chelate with calcium via amino groups without inducing carboxyl or hydroxyl group previously. The complexation of chitosan with calcium ions subsequently absorbed phosphate ions via electrostatic interaction. Calcium phosphate ( CaP ) minerals dispersed in chitosan with the thickness of 0.5 mm is exactly CHA with Ca/P molar ratio of 2.01. The transformation route of CaP salts in chitosan hydrogel started from amorphous
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20

EzEldeen, M., J. Loos, Z. Mousavi Nejad, et al. "3D-printing-assisted fabrication of chitosan scaffolds from different sources and cross-linkers for dental tissue engineering." European Cells and Materials 41 (May 5, 2021): 485–501. http://dx.doi.org/10.22203/ecm.v041a31.

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The aim of the present study was to fabricate and characterise chitosan scaffolds from animal and fungal sources, with or without gelatine as a co-polymer, and cross-linked to 3-glycidyloxyproply trimethoxysilane (GPTMS) or genipin for application in dental root tissue engineering. Chitosan-based scaffolds were prepared by the emulsion freeze-drying technique. Scanning electron microscopy (SEM) and nano-focus computed tomography (nano-CT) were used to characterise scaffold microstructure. Chemical composition and cross-linking were evaluated by Fourier transform infrared-attenuated total refle
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21

Chiono, Valeria, Piergiorgio Gentile, Francesca Boccafoschi, et al. "Photoactive Chitosan Switching on Bone-Like Apatite Deposition." Biomacromolecules 11, no. 2 (2010): 309–15. http://dx.doi.org/10.1021/bm901169v.

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22

Yuliati, Anita, Yuliana Merlindika, Elly Munadziroh, et al. "Mechanical Strength and Porosity of Carbonate Apatite-Chitosan-Gelatine Scaffold in Various Ratio as a Biomaterial Candidate in Tissue Engineering." Key Engineering Materials 829 (December 2019): 173–81. http://dx.doi.org/10.4028/www.scientific.net/kem.829.173.

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Bone defect is a common problem in the field of dentistry. The defect can be solved bytissue engineering. One component of tissue engineering is scaffold. Carbonate apatite is the main material used because it has an organic components similar to human bones. The carbonate apatite combined with gelatin and chitosan can be used as a scaffold for tissue engineering. The aim of thisstudy is to know the exact ratio of the carbonate apatite, chitosan-gelatine (CA:Ch-GEL) scaffold on the compressive strength and porosity size as biomaterial candidates in tissue engineering. Scaffold was synthesized
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23

Park, In Young, Tae Hee Kim, You Kyoung Kim, Yun Jaie Choi, Jae Woon Nah, and Chong Su Cho. "Galactosylated Chitosan/Carbonate Apatite Nanohybridization for Cell Specificity and High Transfection Efficiency as a DNA Carrier." Key Engineering Materials 342-343 (July 2007): 437–40. http://dx.doi.org/10.4028/www.scientific.net/kem.342-343.437.

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The strategies developed for gene delivery are generally classified into two categories of viral and non-viral vectors. The limitation of viral vectors, which have problems including toxicity, immunogenicity and inflammatory response has led to the development of a novel, synthetic vectors based on non-viral vectors. Chitosan, one of non-viral vectors, has been a good candidate in gene delivery field. Moreover, galactosylated chitosan (GC) had the specific recognition of hepatocytes by galactose in the GC. Also, carbonate apatite increased the rate of DNA endocytosis and the efficiency of gene
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24

Xu, Fei, Miao Yin, Huifen Ding, et al. "Evaluation of apatite-coated chitosan microspheres for bone regeneration." Journal of Wuhan University of Technology-Mater. Sci. Ed. 29, no. 2 (2014): 391–97. http://dx.doi.org/10.1007/s11595-014-0927-2.

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25

Peña, J., I. Izquierdo-Barba, M. A. García, and M. Vallet-Regí. "Room temperature synthesis of chitosan/apatite powders and coatings." Journal of the European Ceramic Society 26, no. 16 (2006): 3631–38. http://dx.doi.org/10.1016/j.jeurceramsoc.2005.12.028.

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26

Geçer, Aylin, Nuray Yıldız, Didem Kavak, and Ayla Çalımlı. "Comparison of chitosan apatite composites synthesized by different methods." Polymer Composites 30, no. 3 (2009): 288–95. http://dx.doi.org/10.1002/pc.20635.

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27

Wang, J., J. de Boer, and K. de Groot. "Preparation and Characterization of Electrodeposited Calcium Phosphate/Chitosan Coating on Ti6Al4V Plates." Journal of Dental Research 83, no. 4 (2004): 296–301. http://dx.doi.org/10.1177/154405910408300405.

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Electrolytically deposited carbonate apatite coating demonstrates higher strength but weaker support for bone marrow stromal cell attachment than do biomimetically deposited coatings. It is hypothesized that the incorporation of chitosan will increase the biocompatibility of electrolytic coating while maintaining its original strength. To verify this hypothesis, we formed a hybrid calcium phosphate/chitosan coating through electrodeposition. We found that the incorporation of chitosan influenced calcium phosphate formation and crystallization. Moreover, coating thickness and surface roughness
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28

Gómez-Morales, González-Ramírez, Verdugo-Escamilla, et al. "Induced Nucleation of Biomimetic Nanoapatites on Exfoliated Graphene Biomolecule Flakes by Vapor Diffusion in Microdroplets." Crystals 9, no. 7 (2019): 341. http://dx.doi.org/10.3390/cryst9070341.

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The nucleation of apatite nanoparticles on exfoliated graphene nanoflakes has been successfully carried out by the sitting drop vapor diffusion method, with the aim of producing cytocompatible hybrid nanocomposites of both components. The graphene flakes were prepared by the sonication-assisted, liquid-phase exfoliation technique, using the following biomolecules as dispersing surfactants: lysozyme, L-tryptophan, N-acetyl-D-glucosamine, and chitosan. Results from mineralogical, spectroscopic, and microscopic characterization (X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT
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29

Liu, Yang, Zhongxun Zhang, Huilin Lv, Yong Qin, and Linhong Deng. "Surface modification of chitosan film via polydopamine coating to promote biomineralization in bone tissue engineering." Journal of Bioactive and Compatible Polymers 33, no. 2 (2017): 134–45. http://dx.doi.org/10.1177/0883911517713228.

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Chitosan-based material has been widely used as bone substitute due to its good biocompatibility and biodegradability. However, the hydrophobic surface of chitosan film constrains the osteogenesis mineralization in the process of bone regeneration. For this reason, we develop a novel polydopamine-modified chitosan film suitable for bone tissue engineering applications by a simple and feasible route in this study. Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy confirm the process of surface modification. For comparison, surface wettability, the capacity of minerali
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30

Li, Quan Li, Zhi Qing Chen, Guo Min Ou, et al. "Biomimetic Synthesis of Apatite - Polyelectrolyte Complex (Chitosan - Phosphorylated Chitosan) Hydrogel as an Osteoblast Carrier." Key Engineering Materials 288-289 (June 2005): 75–78. http://dx.doi.org/10.4028/www.scientific.net/kem.288-289.75.

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A novel three-dimensional scaffold of hydroxyapatite(HA)-polyelectrolyte complex (PEC) composite hydrogel was synthesized by a biomimetic method. PEC hydrogel was formed from equal volumes of 1% phosphorylated chitosan in water and 1% chitosan in 1% acetic acid solution. This PEC hydrogel was soaked in saturated Ca(OH)2 solution for 4 d and then in accelerated calcification solution (ACS) for 7 d, both at 37 oC. The PEC hydrogel was a nano-composite material with multiple levels of hierarchical porosity; hydroxyapatite (HA) crystals nucleated and grew on the fiber surfaces of the hydrogel; Rat
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31

Soleymani, Farzad, Rahmatollah Emadi, Sorour Sadeghzade, and Fariborz Tavangarian. "Bioactivity Behavior Evaluation of PCL-Chitosan-Nanobaghdadite Coating on AZ91 Magnesium Alloy in Simulated Body Fluid." Coatings 10, no. 3 (2020): 231. http://dx.doi.org/10.3390/coatings10030231.

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Polymer–ceramic composite coatings on magnesium-based alloys have attracted lots of attention in recent years, to control the speed of degradability and to enhance bioactivity and biocompatibility. In this study, to decrease the corrosion rate in a simulated body fluid (SBF) solution for long periods, to control degradability, and to enhance bioactivity, polycaprolactone–chitosan composite coatings with different percentages of baghdadite (0 wt.%, 3 wt.%, and 5 wt.%) were applied to an anodized AZ91 alloy. According to the results of the immersion test of the composite coating containing 3 wt.
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32

Múzquiz-Ramos, E. M., Dora A. Cortés-Hernández, C. G. Sánchez-Torres, José C. Escobedo-Bocardo, A. Zugasti, and X. S. Ramírez-Gómez. "Biomimetic Magnetic Nanoparticles for Hyperthermia Treatment." Key Engineering Materials 493-494 (October 2011): 16–19. http://dx.doi.org/10.4028/www.scientific.net/kem.493-494.16.

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The aim of this work was the synthesis of bioactive magnetic particles (BMP) which are expected to form a thin apatite layer on its surface that may bond to bone with the osseous carcinogen tissue. Magnetite and Mg0.6Ca0.4Fe2O4 nanoparticles were obtained by a reverse co-precipitation and sol-gel methods, respectively. Magnetite particles were coated with chitosan in order to obtain a stable ferrofluid. Then both ferrites were biomimetically treated using two different simulated body fluids (SBF and 1.5 SBF). An apatite layer was formed on both types of BMP after the biomimetic treatment. Both
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33

Peña, Juan, Isabel Izquierdo-Barba, Alvaro Martínez, and María Vallet-Regí. "New method to obtain chitosan/apatite materials at room temperature." Solid State Sciences 8, no. 5 (2006): 513–19. http://dx.doi.org/10.1016/j.solidstatesciences.2005.11.003.

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34

Yang, Jun, Zhiwen Yao, Changyu Tang, et al. "Growth of apatite on chitosan-multiwall carbon nanotube composite membranes." Applied Surface Science 255, no. 20 (2009): 8551–55. http://dx.doi.org/10.1016/j.apsusc.2009.06.013.

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35

Lee, Min, Weiming Li, Ronald K. Siu, et al. "Biomimetic apatite-coated alginate/chitosan microparticles as osteogenic protein carriers." Biomaterials 30, no. 30 (2009): 6094–101. http://dx.doi.org/10.1016/j.biomaterials.2009.07.046.

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36

Lipton, Anuj Nishanth, Aifa Fathima, and S. G. P. Vincent. "https://microbiologyjournal.org/in-vitro-evaluation-of-chitosan-hydroxyapatite-nanocomposite-scaffolds-as-bone-substitutes-with-antibiofilm-properties/." Journal of Pure and Applied Microbiology 15, no. 3 (2021): 1455–71. http://dx.doi.org/10.22207/jpam.15.3.39.

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An opaque, white chitosan/ Hydroxyapatite nanocomposite was prepared by a simple blend method. Morphology, pore size and dispersion of nano-hydroxyapatite in chitosan matrix were visualized using SEM images. The FTIR and SEM with EDX analysis confirmed the bony apatite layer was formed on the outside of the composite. Porosity measurements and water uptake studies of the nanocomposite were evaluated which revealed the maximum porosity of 80% to 92% in the chitosan: hydroxyapatite nanocomposite at the ratio of 20:80. The results also showed that water absorption ability was inversely proportion
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37

Sharma, Smriti, Vivek P. Soni, and Jayesh R. Bellare. "Chitosan reinforced apatite–wollastonite coating by electrophoretic deposition on titanium implants." Journal of Materials Science: Materials in Medicine 20, no. 7 (2009): 1427–36. http://dx.doi.org/10.1007/s10856-009-3712-6.

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38

Manjubala, I., Igor Ponomarev, Ingo Wilke, and Klaus D. Jandt. "Growth of osteoblast-like cells on biomimetic apatite-coated chitosan scaffolds." Journal of Biomedical Materials Research Part B: Applied Biomaterials 84B, no. 1 (2007): 7–16. http://dx.doi.org/10.1002/jbm.b.30838.

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39

Kumar, R., K. H. Prakash, P. Cheang, L. Gower, and K. A. Khor. "Chitosan-mediated crystallization and assembly of hydroxyapatite nanoparticles into hybrid nanostructured films." Journal of The Royal Society Interface 5, no. 21 (2007): 427–39. http://dx.doi.org/10.1098/rsif.2007.1141.

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The synthesis and subsequent assembly of nearly spherical nano-hydroxyapatite (nHA) particles in the presence of trace amounts of the polysaccharide chitosan was carried out employing a wet chemical approach. Chitosan addition during synthesis not only modulated HA crystallization but also aided in the assembly of nHA particles onto itself. Solvent extraction from these suspensions formed iridescent films, of which the bottom few layers were rich in self-assembled nHA particle arrays. The cross-section of these hybrid films revealed compositional and hence structural grading of the two phases
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40

Ciraldo, Francesca, Kristin Schnepf, Wolfgang Goldmann, and Aldo Boccaccini. "Development and Characterization of Bioactive Glass Containing Composite Coatings with Ion Releasing Function for Antibiotic-Free Antibacterial Surgical Sutures." Materials 12, no. 3 (2019): 423. http://dx.doi.org/10.3390/ma12030423.

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Resorbable (Vicryl® Plus) sutures were coated with zinc-doped glass (Zn-BG) and silver-doped ordered mesoporous bioactive glass (Ag-MBG) particles by a dip coating technique. A multilayer approach was used to achieve robust coatings. The first coating was a polymeric layer (e.g., PCL or chitosan) and the second one was a composite made of BG particles in a polymer matrix. The coatings were characterized in terms of morphology by scanning electron microscopy (SEM), in vitro bioactivity, and antibacterial properties. Chitosan/Ag-MBG coatings showed the ability to form hydroxyl-carbonate-apatite
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GOVINDASAMY, K., C. FERNANDOPULLE, POORIA PASBAKHSH, and K. L. GOH. "SYNTHESIS AND CHARACTERISATION OF ELECTROSPUN CHITOSAN MEMBRANES REINFORCED BY HALLOYSITE NANOTUBES." Journal of Mechanics in Medicine and Biology 14, no. 04 (2014): 1450058. http://dx.doi.org/10.1142/s0219519414500584.

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We report on the electrospinning method to synthesize and characterise chitosan membranes reinforced by halloysite nanotubes (HNTs). The synthesis process addressed two levels of HNTs concentration, i.e., 2 and 5 wt.%. Tensile testing was carried out to determine the strength (σ), strain (ε) at σ and elastic modulus (E) of the membranes. Tensile test data revealed that the membranes reinforced with 5 wt.% HNTs yielded the highest E (0.153 ± 0.02 GPa) and strength (22.53 ± 8.57 MPa). Electron micrographs of the fractured surfaces showed uniform dispersions of HNTs in the chitosan matrix. Infrar
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Yamaguchi, Isamu, Soichiro Itoh, Masumi Suzuki, Akiyoshi Osaka, and Junzo Tanaka. "The chitosan prepared from crab tendons: II. The chitosan/apatite composites and their application to nerve regeneration." Biomaterials 24, no. 19 (2003): 3285–92. http://dx.doi.org/10.1016/s0142-9612(03)00163-7.

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Lewandowska, Katarzyna, and Gabriel Furtos. "Study of apatite layer formation on SBF-treated chitosan composite thin films." Polymer Testing 71 (October 2018): 173–81. http://dx.doi.org/10.1016/j.polymertesting.2018.09.007.

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Manjubala, I., S. Scheler, Jörg Bössert, and Klaus D. Jandt. "Mineralisation of chitosan scaffolds with nano-apatite formation by double diffusion technique." Acta Biomaterialia 2, no. 1 (2006): 75–84. http://dx.doi.org/10.1016/j.actbio.2005.09.007.

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Li, Baoqiang, Yongliang Wang, Dechang Jia, and Yu Zhou. "Gradient Structural Bone-Like Apatite Induced by Chitosan Hydrogel via Ion Assembly." Journal of Biomaterials Science, Polymer Edition 22, no. 4-6 (2011): 505–17. http://dx.doi.org/10.1163/092050610x487800.

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Virk, Ranjot Singh, Muhammad Atiq Ur Rehman, Muhammad Azeem Munawar, et al. "Curcumin-Containing Orthopedic Implant Coatings Deposited on Poly-Ether-Ether-Ketone/Bioactive Glass/Hexagonal Boron Nitride Layers by Electrophoretic Deposition." Coatings 9, no. 9 (2019): 572. http://dx.doi.org/10.3390/coatings9090572.

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Electrophoretic deposition (EPD) was used to produce a multilayer coatings system based on chitosan/curcumin coatings on poly-ether-ether-ketone (PEEK)/bioactive glass (BG)/hexagonal boron nitride (h-BN) layers (previously deposited by EPD on 316L stainless steel) to yield bioactive and antibacterial coatings intended for orthopedic implants. Initially, PEEK/BG/h-BN coatings developed on 316L stainless steel (SS) substrates were analyzed for wear studies. Then, the EPD of chitosan/curcumin was optimized on 316L SS for suspension stability, thickness, and homogeneity of the coatings. Subsequent
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Monárrez-Cordero, Blanca Elizabeth, Claudia Alejandra Rodríguez-González, Laura Elizabeth Valencia-Gómez, et al. "The effect of Allium cepa extract on the chitosan/PLGA scaffolds bioactivity." Journal of Applied Biomaterials & Functional Materials 19 (January 2021): 228080002198970. http://dx.doi.org/10.1177/2280800021989701.

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Allium cepa extracts (AC) allow the fabrication of a biomaterial that, together with chitosan and PLGA, could be osteoconductive and promote a better and faster regeneration of bone tissue, with biocompatibility and biomineralization properties. In this work, scaffolds were developed by the thermally induced phase separation (TIPS) technique. An in vitro bioactivity analysis was performed using simulated body fluid (SBF). Scanning electron microscopy (SEM), energy dispersion spectroscopy, and infrared spectroscopy were used for the scaffolds characterization. The results showed a structure wit
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Maretaningtias Dwi Ariani, Anita Yuliati, and Utari Kresnoadi. "UJI IN VITRO CARBONATE APATITE-CHITOSAN SCAFFOLDS SEBAGAI MATERIAL CANGKOK TULANG PADA TEKNIK REKAYASA JARINGAN." Dentika: Dental Journal 18, no. 1 (2014): 10. http://dx.doi.org/10.32734/dentika.v18i1.1921.

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Untuk meningkatkan adhesi sel dan kemampuan pembentukan tulang dari kitosan, dicoba untuk membuat suatuscaffolds yang menggabungkan kitosan dengan carbonate apatite (CA). Tujuan penelitian ini adalah untukmembuat carbonate apatite-chitosan scaffolds (CA-ChSs) serta mengevaluasi CA-ChSs dari sudut pandangproliferasi sel menggunakan MC3T3-E1. Chitosan scaffolds (ChSs) yang berisi 25, 50, 75, 100, 125, 150, 200dan 400 mg bubuk kitosan (100D, YSK, Japan) dibuat dengan prosedur dilarutkan dalam 5 ml asam asetat 2%,dikocok selama 15 menit, kemudian dinetralkan dengan 15 ml 0,1 M larutan NaOH. Setela
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ul Haq, Tauheed, Sami Ullah, and Rehman Ullah. "Beneficial Effects of Several Nanoparticles on the Growth of Different Plants Species." Current Nanoscience >15, no. 5 (2019): 460–70. http://dx.doi.org/10.2174/1573413715666190104143705.

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The excessive use of nitrogen and phosphorous fertilizers led to environmental pollution and serious health issues. Nanotechnology may solve such a type of problems by providing nanomaterials of high performance. Here, we reviewed the beneficial effects of some different nanoparticles on the growth of different parts of different plants belonging to 14 different families. Nanoparticles such as CNT, Ag-NPs, TiO2-NPs, Au-NPs, S-NPs, Ag-NPs+ Magnetic field-NPs, ZnO-NPs, Fe-NPs, SiO2-NPs, RA-NPs, Zinc-NPs, Silica-NPs, Apatite-NPs, CeO2-NPs, Cu-NPs, CaCO3-NPs, Chitosan- NKP-NPs and Carbon nono-tube
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Jalali Dehkordi, Mahshid, Abbas Bahrami, Mohammad Saeid Abbasi та ін. "Surface Modification of Anodized Titanium Surfaces with Chitosan/ε-Polylysine Coating, Aiming for an Improved Bioactivity, Biocompatibility, and Anti-Bacterial Properties for Orthopedic Applications". Coatings 14, № 12 (2024): 1522. https://doi.org/10.3390/coatings14121522.

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The increasidng demand for implants due to the aging populations highlights the necessity for applying highly functional coatings on the surface of implants. This study investigates the implications of applying a chitosan/polylysine composite coating on anodized titanium surfaces, aiming for improved biocompatibility, bioactivity, and anti-bacterial properties. Titanium substrates were anodized at 40 volts for a duration of two hours, followed by dip coating with the chitosan/polylysine composite. Fourier-transform infrared (FTIR) analysis was employed to characterize the polymer structure, wh
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