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Relevant bibliographies by topics / Chitosan nerve guide

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Academic literature on the topic 'Chitosan nerve guide'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Chitosan nerve guide"

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Stenberg, Lena, Maria Stößel, Giulia Ronchi, et al. "Regeneration of long-distance peripheral nerve defects after delayed reconstruction in healthy and diabetic rats is supported by immunomodulatory chitosan nerve guides." BMC Neuroscience 18, no. 1 (2017): 53. https://doi.org/10.1186/s12868-017-0374-z.

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<strong>Background: </strong>Delayed reconstruction of transection or laceration injuries of peripheral nerves is inflicted by a reduced regeneration capacity. Diabetic conditions, more frequently encountered in clinical practice, are known to further impair regeneration in peripheral nerves. Chitosan nerve guides (CNGs) have recently been introduced as a new generation of medical devices for immediate peripheral nerve reconstruction. Here, CNGs were used for 45 days delayed reconstruction of critical length 15 mm rat sciatic nerve defects in either healthy Wistar rats or diabetic Goto-Kakizak

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Lin, Chuang Yu, Li Tzu Li, and Wen Ta Su. "Cell Cycle Analysis of Rat Schwann Cells on Chitosan Scaffolds by Flow Cytometry." Applied Mechanics and Materials 284-287 (January 2013): 46–50. http://dx.doi.org/10.4028/www.scientific.net/amm.284-287.46.

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The fine combination of biomaterial and essential cells determines a successful artificial graft. With high biocompatibility, chitosan is a choice of materials for regeneration medicine. In the peripheral nervous system, Schwann cells are critical for nerve regeneration. Schwann cells not only help to conduct the nerve pulse but also guide the nerve extension, especially the injured nerve for recovery. Studies showed that chitosan can be a bridge material for damaged nerve regeneration. The interactions between chitosan and Schwann cells may provide important information for designing the chit

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Stößel, Maria, Jennifer Metzen, Vivien M. Wildhagen, et al. "Long-Term In Vivo Evaluation of Chitosan Nerve Guide Properties with respect to Two Different Sterilization Methods." BioMed Research International 2018 (June 4, 2018): 1–11. http://dx.doi.org/10.1155/2018/6982738.

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Severe peripheral nerve injuries are reconstructed either with autologous nerve grafts (gold standard) or alternatively with clinically approved artificial nerve guides. The most common method used to sterilize these medical products is ethylene oxide gassing (EO). However, this method has several disadvantages. An alternative, which has been barely studied so far, represents beta irradiation (β). In previous studies, we developed an artificial nerve guide made of chitosan (chitosan nerve guide, CNG), a biomaterial that is known to potentially retain toxic residues upon EO sterilization. There

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Huang, Zhong, Svenja Kankowski, Ella Ertekin, et al. "Modified Hyaluronic Acid-Laminin-Hydrogel as Luminal Filler for Clinically Approved Hollow Nerve Guides in a Rat Critical Defect Size Model." International Journal of Molecular Sciences 22, no. 12 (2021): 6554. http://dx.doi.org/10.3390/ijms22126554.

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Hollow nerve guidance conduits are approved for clinical use for defect lengths of up to 3 cm. This is because also in pre-clinical evaluation they are less effective in the support of nerve regeneration over critical defect lengths. Hydrogel luminal fillers are thought to improve the regeneration outcome by providing an optimized matrix inside bioartificial nerve grafts. We evaluated here a modified hyaluronic acid-laminin-hydrogel (M-HAL) as luminal filler for two clinically approved hollow nerve guides. Collagen-based and chitosan-based nerve guides were filled with M-HAL in two different c

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Gomes, J., Jorge R.M. Natal, and J. Belinha. "An elastoplastic constitutive model to simulate the non-linear behaviour of chitosan material for nerve regeneration guide tubes applications." Journal of Computation and Artificial Intelligence in Mechanics and Biomechanics 2, no. 2 (2022): 97–110. https://doi.org/10.5281/zenodo.7492983.

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Neurotmesis is the most severe injury a peripheral nerve can endure. One of the strategies to treat this type of nerve injury is the tubulization technique, consisting of bridging the two nerve tips enclosed by a tube made of a compatible biomaterial. Chitosan scaffolds is one of the most popular (and successful) solutions used for the tubulization technique. After implanting the chitosan tube, it will experience mechanical stimuli due to natural movements, inducing strain-stress states in the biomaterial. It is relevant to characterize the mechanical behaviour of chitosan scaffolds in order t

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Sierakowska-Byczek, Aleksandra, Julia Radwan-Pragłowska, Łukasz Janus, et al. "Environment-Friendly Preparation and Characterization of Multilayered Conductive PVP/Col/CS Composite Doped with Nanoparticles as Potential Nerve Guide Conduits." Polymers 16, no. 7 (2024): 875. http://dx.doi.org/10.3390/polym16070875.

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Tissue engineering constitutes the most promising method of severe peripheral nerve injuries treatment and is considered as an alternative to autografts. To provide appropriate conditions during recovery special biomaterials called nerve guide conduits are required. An ideal candidate for this purpose should not only be biocompatible and protect newly forming tissue but also promote the recovery process. In this article a novel, multilayered biomaterial based on polyvinylpyrrolidone, collagen and chitosan of gradient structure modified with conductive nanoparticles is presented. Products were

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Li, Xiaoxia, Wei Wang, Guoqiang Wei, Guanxiong Wang, Weiguo Zhang, and Xiaojun Ma. "Immunophilin FK506 loaded in chitosan guide promotes peripheral nerve regeneration." Biotechnology Letters 32, no. 9 (2010): 1333–37. http://dx.doi.org/10.1007/s10529-010-0287-8.

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Alvites, Rui D., Mariana V. Branquinho, Ana C. Sousa, et al. "Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo." Stem Cells International 2021 (January 2, 2021): 1–32. http://dx.doi.org/10.1155/2021/6613029.

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Peripheral nerve injury remains a clinical challenge with severe physiological and functional consequences. Despite the existence of multiple possible therapeutic approaches, until now, there is no consensus regarding the advantages of each option or the best methodology in promoting nerve regeneration. Regenerative medicine is a promise to overcome this medical limitation, and in this work, chitosan nerve guide conduits and olfactory mucosa mesenchymal stem/stromal cells were applied in different therapeutic combinations to promote regeneration in sciatic nerves after neurotmesis injury. Over

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Cárdenas-Triviño, Galo, and Rodrigo Soto-Seguel. "CHITOSAN COMPOSITES PREPARATION AND CHARACTERIZATION OF GUIDE TUBES FOR NERVE REPAIR." Journal of the Chilean Chemical Society 65, no. 3 (2020): 4870–78. http://dx.doi.org/10.4067/s0717-97072020000204870.

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Russo, Teresa, Stefania Scialla, Marietta D’Albore, Iriczalli Cruz-Maya, Roberto De Santis, and Vincenzo Guarino. "An Easy-to-Handle Route for Bicomponent Porous Tubes Fabrication as Nerve Guide Conduits." Polymers 16, no. 20 (2024): 2893. http://dx.doi.org/10.3390/polym16202893.

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Over the past two decades, the development of nerve guide conduits (NGCs) has gained much attention due to the impellent need to find innovative strategies to take care of damaged or degenerated peripheral nerves in clinical surgery. In this view, significant effort has been spent on the development of high-performance NGCs by different materials and manufacturing approaches. Herein, a highly versatile and easy-to-handle route to process 3D porous tubes made of chitosan and gelatin to be used as a nerve guide conduit were investigated. This allowed us to fabricate highly porous substrates with

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Dissertations / Theses on the topic "Chitosan nerve guide"

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Stößel, Maria [Verfasser]. "Evaluation of enhanced chitosan nerve guides in hindlimb and forelimb rat models of peripheral nerve regeneration / Maria Stößel." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2017. http://d-nb.info/1160495262/34.

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Dietzmeyer, Nina [Verfasser], Kirsten [Akademischer Betreuer] Haastert-Talini, Marion Akademischer Betreuer] Bankstahl, and Florian [Akademischer Betreuer] [Beißner. "Modifications of tubular chitosan nerve guides and their potential to increase peripheral nerve regeneration in rat models : implications from novel material properties and hydrogel fillers for Schwann cell delivery / Nina Dietzmeyer ; Kirsten Haastert-Talini, Marion Bankstahl, Florian Beißner." Hannover : Stiftung Tierärztliche Hochschule Hannover, 2020. http://nbn-resolving.de/urn:nbn:de:gbv:95-114183.

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Dietzmeyer, Nina [Verfasser], Kirsten [Akademischer Betreuer] Haastert-Talini, Marion [Akademischer Betreuer] Bankstahl, and Florian [Akademischer Betreuer] Beißner. "Modifications of tubular chitosan nerve guides and their potential to increase peripheral nerve regeneration in rat models : implications from novel material properties and hydrogel fillers for Schwann cell delivery / Nina Dietzmeyer ; Kirsten Haastert-Talini, Marion Bankstahl, Florian Beißner." Hannover : Stiftung Tierärztliche Hochschule Hannover, 2020. http://d-nb.info/1217249486/34.

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Carvalho, Cristiana Rodrigues. "Combinatorial approaches for the development of conduits for guided peripheral nerve regeneration." Doctoral thesis, 2019. http://hdl.handle.net/1822/66127.

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Tese de doutoramento em Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais<br>Regeneration, reconstruction and repair of peripheral nerve injuries (PNIs) are among the most complex and demanding challenges in the field of regenerative medicine. As a promising alternative to the “gold standard” autologous nerve grafts, tissue-engineered nerve guidance conduits (NGCs) have been extensively studied. However, in order to be able to produce an adequate NGC, the basic principles of neuro-biology must be known and followed. Also, great efforts have been made in terms of pre-clinic

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Book chapters on the topic "Chitosan nerve guide"

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Fregnan, Federica, Michela Morano, Ofra Ziv-Polat, et al. "Effect of Local Delivery of GDNF Conjugated Iron Oxide Nanoparticles on Nerve Regeneration along Long Chitosan Nerve Guide." In Peripheral Nerve Regeneration - From Surgery to New Therapeutic Approaches Including Biomaterials and Cell-Based Therapies Development. InTech, 2017. http://dx.doi.org/10.5772/intechopen.68526.

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Conference papers on the topic "Chitosan nerve guide"

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Li, Ching-Wen, and Gou-Jen Wang. "Double-Layer Nerve Guide Conduit With Palisade Poly(Lactic-Co-Glycolic Acid) Tube Wrapped by Microporous Chitosan-Collagen Composite." In ASME 2017 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/detc2017-67109.

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In this study, a double-layer nerve guide conduit (DLNGC) that comprises an inner poly(lactic-co-glycolic acid) (PLGA) scaffold with palisade structure and an outer micro-porous chitosan-collagen composite (CSC) membrane was developed. The PLGA scaffold was fabricated using the commonly used soft-lithography process and then rolled into a tube. The micro-porous CSC membrane was fabricated by lyophilization (freeze-drying), with its pore size being controlled by the chitosan:collagen weight ratio. The CSC properties such as water absorption rate, permeation rate, and biocompatibility were then

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