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1

Xie, Kailiu, Yonghui Pan, Xusheng Meng, Min Wang, and Shiwei Guo. "Critical Leaf Magnesium Thresholds for Growth, Chlorophyll, Leaf Area, and Photosynthesis in Rice (Oryza sativa L.) and Cucumber (Cucumis sativus L.)." Agronomy 14, no. 7 (2024): 1508. http://dx.doi.org/10.3390/agronomy14071508.

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Accurately understanding the critical threshold of leaf magnesium (Mg) concentration is crucial for rapid diagnosis of crop Mg status; however, little information is available on critical Mg concentration for different physiological processes in dicots and monocots. Here, we investigated the sensitivity of biomass, chlorophyll (Chl) at different leaf positions/ages, leaf area (LA), and photosynthesis (Pn) to Mg deficiency between rice (Oryza sativa L.) and cucumber (Cucumis sativus L.). Plants were grown hydroponically under twelve Mg concentration gradients. Results showed reducing the extern
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2

Alibrahim, Mohamed Nazem, Annunziata Gloghini, and Antonino Carbone. "Immune Deficiency/Dysregulation-Associated EBV-Positive Classic Hodgkin Lymphoma." Cancers 17, no. 9 (2025): 1433. https://doi.org/10.3390/cancers17091433.

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Classic Hodgkin lymphoma (cHL) in patients with immune deficiency/dysregulation represents a critical unmet need in hematology, demanding the appropriate revision of classification and therapeutic paradigms. Epstein–Barr virus (EBV) is a pivotal driver of lymphomagenesis in this high-risk subset, where viral oncoproteins (e.g., LMP1/2A) exploit immune vulnerabilities to activate NF-κB, rewire tumor microenvironments (TME), and evade immune surveillance. EBV-positive cHL, prevalent in immunosuppressed populations, exhibits distinct molecular hallmarks, including reduced somatic mutations, uniqu
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3

Larbi, Ajmi, Fermín Morales, Anunciación Abadía, Yolanda Gogorcena, Juan J. Lucena, and Javier Abadía. "Effects of Cd and Pb in sugar beet plants grown in nutrient solution: induced Fe deficiency and growth inhibition." Functional Plant Biology 29, no. 12 (2002): 1453. http://dx.doi.org/10.1071/fp02090.

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Effects of Cd and Pb toxicity were investigated in sugar beet (Beta vulgaris L.) grown in hydroponics under growth-chamber-controlled conditions. Chemical speciation calculations were used to estimate the chemical species in equilibrium. Cd, used as chloride salt or chelated to EDTA, decreased fresh and dry mass of both root and shoot, and increased root / shoot ratios. Plants developed few brownish roots with short laterals. Cd decreased N, P, Mg, K, Mn, Cu and Zn uptake, and facilitated Ca uptake. Leaves of plants treated with 10 or 50 μM Cd–EDTA and 10 μM CdCl2 developed symptoms of Fe defi
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4

Smith*, Brandon, and Lailiang Cheng. "Photoprotective Mechanisms of Grape Leaves (Vitis labrusca L. cv. Concord) in Relation to Iron Supply." HortScience 39, no. 4 (2004): 854A—854. http://dx.doi.org/10.21273/hortsci.39.4.854a.

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One-year-old `Concord' grapevines (Vitis labrusca L.) were fertigated twice weekly for 11 weeks with a complete nutrient solution containing 1, 10, 20, 50 or 100 μmol iron (Fe) from ferric ethylenediamine di (o-hydroxyphenylacetic) acid (Fe-EDDHA). Leaf total Fe content did not increase in response to Fe supply, however both “active” Fe (extracted with 2, 2'-dipyridyl) and chlorophyll (Chl) content increased as applied Fe increased. At the lowest active Fe level, leaf absorptance and maximum PSII efficiency (Fv/Fm) were slightly decreased, and non-photochemical quenching was significantly grea
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5

Wang, Peng, Fu-Cheng Liang, Daniel Wittmann, Alex Siegel, Shu-ou Shan, and Bernhard Grimm. "Chloroplast SRP43 acts as a chaperone for glutamyl-tRNA reductase, the rate-limiting enzyme in tetrapyrrole biosynthesis." Proceedings of the National Academy of Sciences 115, no. 15 (2018): E3588—E3596. http://dx.doi.org/10.1073/pnas.1719645115.

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Assembly of light-harvesting complexes requires synchronization of chlorophyll (Chl) biosynthesis with biogenesis of light-harvesting Chl a/b-binding proteins (LHCPs). The chloroplast signal recognition particle (cpSRP) pathway is responsible for transport of nucleus-encoded LHCPs in the stroma of the plastid and their integration into the thylakoid membranes. Correct folding and assembly of LHCPs require the incorporation of Chls, whose biosynthesis must therefore be precisely coordinated with membrane insertion of LHCPs. How the spatiotemporal coordination between the cpSRP machinery and Chl
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6

Meng, Xin, Wei-Wei Chen, Yan-Yu Wang, et al. "Effects of phosphorus deficiency on the absorption of mineral nutrients, photosynthetic system performance and antioxidant metabolism in Citrus grandis." PLOS ONE 16, no. 2 (2021): e0246944. http://dx.doi.org/10.1371/journal.pone.0246944.

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Phosphorus (P) is an essential macronutrient for plant growth, development and production. However, little is known about the effects of P deficiency on nutrient absorption, photosynthetic apparatus performance and antioxidant metabolism in citrus. Seedlings of ‘sour pummelo’ (Citrus grandis) were irrigated with a nutrient solution containing 0.2 mM (Control) or 0 mM (P deficiency) KH2PO4 until saturated every other day for 16 weeks. P deficiency significantly decreased the dry weight (DW) of leaves and stems, and increased the root/shoot ratio in C. grandis but did not affect the DW of roots.
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7

Endo, Hikaru, Hikari Moriyama, and Yutaka Okumura. "Photoinhibition and Photoprotective Responses of a Brown Marine Macroalga Acclimated to Different Light and Nutrient Regimes." Antioxidants 12, no. 2 (2023): 357. http://dx.doi.org/10.3390/antiox12020357.

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Plants and brown algae avoid photoinhibition (decline in photosystem II efficiency, Fv/Fm) caused by excess light energy and oxidative stress through several photoprotective mechanisms, such as antioxidant xanthophyll production and heat dissipation. The heat dissipation can be measured as non-photochemical quenching (NPQ) and is strongly driven by de-epoxidation of xanthophyll cycle pigments (XCP). Although NPQ is known to increase under high light acclimation and nutrient-deficient conditions, a few studies have investigated the combined effects of the conditions on both NPQ and associated x
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8

Aytekin, Gökhan, Fatih Çölkesen, Eray Yıldız, Mitat Arıcıgil, and Şevket Arslan. "Hearing Assessment in Adult Patients with Common Variable Immunodeficiency." Asthma Allergy Immunology 19, no. 1 (2021): 38–45. http://dx.doi.org/10.21911/aai.600.

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ABSTRACT Objective: Common Variable Immunodeficiency (CVID) is a primary antibody disorder characterized by impaired B cell differentiation. Patients commonly present with acute and chronic sinusitis as well as otitis media, which may lead to hearing loss. Materials and Methods: Thirty-three CVID patients (20 male /13 female) with a mean age of 35 years (range 19-65 years) and 33 healthy individuals as a control group were included. Results: Among CVID patients, 17 (51.5%) had conductive hearing loss (CHL) , being unilateral in 4 (12.1%) and bilateral in 13 (39.4%). Unilateral and bilateral se
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9

Gao, Dapeng, Cheng Ran, Kun Dang, et al. "Effect of Phosphorus, Iron, Zinc, and Their Combined Deficiencies on Photosynthetic Characteristics of Rice (Oryza sativa L.) Seedlings." Agronomy 13, no. 6 (2023): 1657. http://dx.doi.org/10.3390/agronomy13061657.

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Combined elemental deficiencies are more complex and insidious physiological metabolic responses than single elemental stresses. To determine the effects of phosphorus (P), iron (Fe), zinc (Zn), and their deficient combinations on photosynthetic characteristics of rice seedlings, we investigated their effects on dry weight, chlorophyll (Chl) content, rapid photosynthetic carbon assimilation CO2 responses, and Chl fluorescence in four-week-old rice (CB9 and BJ1 cultivars) seedlings. The results showed that the dry matter, maximum carboxylation efficiency (Vc,max), and maximum electron transfer
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10

JUNWAL, MANJU, and BHAI ISMAIL. "A case study of Human iron deficiency Anaemia in different age groups from Ujjain (M.P.) India." Journal of Ultra Scientist of Physical Sciences Section B 33, no. 3 (2021): 12–18. http://dx.doi.org/10.22147/jusps-b/330301.

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Iron deficiency Anaemia is the most common case of nutritional Anaemia worldwide and is a public health problem in developing countries; characterized by abnormal red cell count (MCV, MCHC). Iron deficiency Anaemia associated with fatigue, skin paleness, weakness etc. The aim of the study is to determine the risk factors for iron deficiency Anaemia among population of Ujjain district (M.P.). Both male and female iron deficient patients were studied from the SS hospital and CHL applo hospitals during Jan. 2012 to Dec. 2012. A group of 6828 patients were studied for iron deficiency Anaemia in di
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11

Chen, Guangyu E., Andrew Hitchcock, Jan Mareš, et al. "Evolution of Ycf54-independent chlorophyll biosynthesis in cyanobacteria." Proceedings of the National Academy of Sciences 118, no. 10 (2021): e2024633118. http://dx.doi.org/10.1073/pnas.2024633118.

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Chlorophylls (Chls) are essential cofactors for photosynthesis. One of the least understood steps of Chl biosynthesis is formation of the fifth (E) ring, where the red substrate, magnesium protoporphyrin IX monomethyl ester, is converted to the green product, 3,8-divinyl protochlorophyllide a. In oxygenic phototrophs, this reaction is catalyzed by an oxygen-dependent cyclase, consisting of a catalytic subunit (AcsF/CycI) and an auxiliary protein, Ycf54. Deletion of Ycf54 impairs cyclase activity and results in severe Chl deficiency, but its exact role is not clear. Here, we used a Δycf54 mutan
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12

Pestana, Maribela, Pedro García-Caparrós, Teresa Saavedra, et al. "Nutritional Performance of Five Citrus Rootstocks under Different Fe Levels." Plants 12, no. 18 (2023): 3252. http://dx.doi.org/10.3390/plants12183252.

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Iron is an essential micronutrient for citrus, playing an important role in photosynthesis and yield. The aim of this paper was to evaluate the tolerance to Fe deficiency of five citrus rootstocks: sour orange (S), Carrizo citrange (C), Citrus macrophylla (M), Troyer citrange (T), and Volkamer lemon (V). Plants were grown for 5 weeks in nutrient solution that contained the following Fe concentrations (in µM): 0, 5, 10, 15, and 20. At the end of the experiment, biomass (dry weight—DW), leaf area, total leaf chlorophyll (CHL), and the activity of root chelate reductase (FCR) were recorded. Addit
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13

Samborska, Izabela A., Hazem M. Kalaji, Leszek Sieczko, Vasilij Goltsev, Wojciech Borucki, and Anjana Jajoo. "Structural and functional disorder in the photosynthetic apparatus of radish plants under magnesium deficiency." Functional Plant Biology 45, no. 6 (2018): 668. http://dx.doi.org/10.1071/fp17241.

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Magnesium (Mg) is one of the significant macronutrients which is involved in the structural stabilisation of plant tissues and many enzymes such as PSII. The latter efficiency and performance were analysed, using chlorophyll (Chl) a fluorescence induction kinetics and microscopic images, to detect the changes in structure and function of photosynthetic apparatus of radish plants grown under Mg deficiency (Mgdef). Plants grown under Mgdef showed less PSII connectivity and fewer active primary electron acceptors (QA) oxidizing reaction centres than control plants. Confocal and electron microscop
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14

Jeong, Ah-Reum, Edward D. Ball, and Aaron Michael Goodman. "Predicting Responses to Checkpoint Inhibitors in Lymphoma: Are We Up to the Standards of Solid Tumors?" Clinical Medicine Insights: Oncology 14 (January 2020): 117955492097636. http://dx.doi.org/10.1177/1179554920976366.

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Treatment of cancer has transformed with the introduction of checkpoint inhibitors. However, the majority of solid tumor patients do not respond to checkpoint blockade. In contrast, the response rate to programmed cell death 1 (PD-1) blockade in relapsed/refractory classical Hodgkin lymphoma (cHL) is 65% to 84% which is the highest among all cancers. Currently, checkpoint inhibitors are only approved for cHL and primary mediastinal B-cell lymphoma as the responses to single-agent checkpoint blockade in other hematologic malignancies is disappointingly low. Various established biomarkers such a
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15

Nair, Ranjit, Samer Al Hadidi, Raphael Eric Steiner, et al. "Association of Vitamin D Deficiency with Inferior Treatment Outcomes in Patients with Newly Diagnosed Classic Hodgkin Lymphoma: MD Anderson Cancer Center Experience." Blood 136, Supplement 1 (2020): 27–28. http://dx.doi.org/10.1182/blood-2020-142139.

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Introduction Vitamin D deficiency is a modifiable risk factor for multiple malignancies. There is growing evidence that associates vitamin D deficiency with progression-free survival (PFS) and overall survival (OS) in patients with classic Hodgkin lymphoma (cHL). Supplemental ergocalciferol/cholecalciferol may improve chemosensitivity of malignant cells to chemotherapy as evidenced by reduction in the rate of tumor growth in a cHL- xenograft animal model. The goal of our study is to explore the association of pretreatment vitamin D levels on survival outcomes of patients with cHL. Methods We r
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16

Chen, Ling-Hua, Ming Xu, Zuxin Cheng, and Lin-Tong Yang. "Effects of Nitrogen Deficiency on the Photosynthesis, Chlorophyll a Fluorescence, Antioxidant System, and Sulfur Compounds in Oryza sativa." International Journal of Molecular Sciences 25, no. 19 (2024): 10409. http://dx.doi.org/10.3390/ijms251910409.

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Decreasing nitrogen (N) supply affected the normal growth of Oryza sativa (O. sativa) seedlings, reducing CO2 assimilation, stomatal conductance (gs), the contents of chlorophylls (Chl) and the ratio of Chl a/Chl b, but increasing the intercellular CO2 concentration. Polyphasic chlorophyll a fluorescence transient and relative fluorescence parameters (JIP test) results indicated that N deficiency increased Fo, but decreased the maximum quantum yield of primary photochemistry (Fv/Fm) and the maximum of the IPphase, implying that N-limiting condition impaired the whole photo electron transport c
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17

Graves, William R., and Carrie E. Green. "INFLUENCE OF Fe CHELATES AND pH ON HEAT-INDUCED CHLOROSIS IN SEEDLINGS OF HONEY LOCUST." HortScience 28, no. 5 (1993): 499f—499. http://dx.doi.org/10.21273/hortsci.28.5.499f.

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We observed previously that a root-zone temperature (RZT) of 34C caused severe chlorosis of Gleditsia triacanthos L. var. inermis Willd. (thornless honey locust) grown in solution. To determine whether the form of Fe chelate or the solution pH influence chlorosis, we measured growth, chlorophyll (Chl) content, and essential elements in solution-cultured seedlings treated with different chelate forms (Fe-EDTA, Fe-EDDHA, or no Fe), pH (5.4 or 7.0 upon weekly replacements), and RZT (23 or 34C). Chelate form and pH did not affect the development of chlorosis. Reductions of at least 50% Chl were in
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18

Smith, Brandon R., and Lailiang Cheng. "Photoprotective Mechanisms of `Concord' Grape Leaves in Relation to Iron Supply." Journal of the American Society for Horticultural Science 130, no. 3 (2005): 331–40. http://dx.doi.org/10.21273/jashs.130.3.331.

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The objective of this study was to quantify how photoprotective mechanisms in the leaves of `Concord' grapevines (Vitis labruscana Bailey) respond to a range of iron (Fe) supply. Own-rooted, 1-year-old container-grown vines were fertigated twice weekly for 11 weeks with a complete nutrient solution containing 1, 10, 20, 50, or 100 μm Fe from ferric ethylenediamine di (o-hydroxyphenylacetic) acid (Fe-EDDHA). Leaf total Fe content did not increase in response to Fe supply; however, “active” Fe (extracted with 2,2′-dipyridyl) and chlorophyll (Chl) increased on a leaf area basis as applied Fe incr
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19

Kilic, Nihat, Ali Kiki, Hüsamettin Oktay, and Erol Selimoglu. "Effects of Rapid Maxillary Expansion on Conductive Hearing Loss." Angle Orthodontist 78, no. 3 (2008): 409–14. http://dx.doi.org/10.2319/050407-217.1.

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Abstract Objective: To test the null hypothesis that rapid maxillary expansion (RME) with a rigid bonded appliance has no effect on conductive hearing loss (CHL) in growing children. Materials and Methods: Fifteen growing subjects (mean age 13.43 ± 0.86 years) who had narrow maxillary arches and CHL participated in this study. Three pure-tone audiometric and tympanometric records were taken from each subject. The first records were taken before RME (T1), the second after maxillary expansion (T2) (mean = 0.83 months), and the third after retention (mean = 6 months) and fixed appliance treatment
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20

Nagase, Shunsuke, Yara Yukie Kikuti, Joaquim Carreras, Hiroshi Kawada, and Naoya Nakamura. "The Spectrum of Epstein-Barr Virus (EBV)-Positive Diffuse Large B-Cell Lymphoma and EBV-Positive Classic Hodgkin Lymphoma: A Proposed Classification of EBV-Positive Large B-Cell Lymphoma." Blood 144, Supplement 1 (2024): 6253. https://doi.org/10.1182/blood-2024-206156.

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Introduction: Epstein Barr virus (EBV)-positive diffuse large B-cell lymphoma (DLBCL) is a large B-cell lymphoma with EBV infection which mostly occur in elderly patients. A histological continuum from monomorphic (mDLBCL) to polymorphic (pDLBCL) has been described. Since some cases of pDLBCL mimic classic Hodgkin lymphoma (CHL), distinguishing EBV+DLBCL from EBV+CHL could be a diagnostic problem. A previous study defined cases with CD20+ neoplastic cells ≥50% as EBV+DLBCL and <50% as EBV+CHL (Asano N, et al. Blood. 2009). However, this criterion is arbitrary, and the boundary between t
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21

Nikolaev, S. V., and V. L. Yaluga. "Genetic characteristics of producing bulls of the Kholmogorsky breed, depending on their linear affiliation and the level of Holstein." Agrarian science, no. 6 (June 14, 2024): 77–81. http://dx.doi.org/10.32634/0869-8155-2024-383-6-77-81.

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Relevance. Genetic analysis using STR markers makes it possible to effectively use various techniques to control the breeding process in a population.Methods. The material for DNA research was the deep-frozen sperm of 103 bulls-producers of the Kholmogorsky breed, with different blood levels of Holstein cattle belonging to five main genealogical lines. Molecular genetic studies were conducted in the laboratory of DNA technologies at VNIIPlem.Results. The animals of the VBA (I = 1,557) and Nl (I = 1,556) lines had the maximum genetic diversity, and the Chl lines had the lowest (the indicator is
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22

Ji, Shuiling, Huijiao Yao, and Bernhard Grimm. "Coordinated cpSRP43 and cpSRP54 Abundance Is Essential for Tetrapyrrole Biosynthesis While cpSRP43 Is Independent of Retrograde Signaling." Plants 14, no. 12 (2025): 1745. https://doi.org/10.3390/plants14121745.

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The chloroplast signal recognition particle (cpSRP) components cpSRP43 and cpSRP54 not only form a complex with light-harvesting chlorophyll (Chl)-binding proteins to direct them to the thylakoid membrane, but also serve other functions. cpSRP43 independently acts as a chaperone for some tetrapyrrole biosynthesis (TBS) enzymes, while cpSRP54 participates in the co-translational targeting of plastid-encoded proteins. However, it remains unclear to what extent the two cpSRP components are coregulated—despite their distinct functions—and whether both participate in genomes-uncoupled (GUN)-mediate
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23

UNAL, EKREM. "The Effect of Nivolumab in Pediatric Malignant Tumors: A Single Center Experience with Nine Children." International Journal of Hematology and Oncology 34, no. 4 (2024): 184–94. https://doi.org/10.4999/uhod.247791.

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Nivolumab is an inhibitor of programmed cell death 1 (PD-1), which enables activated T cells to attack the tumor cells. Although the utilization of nivolumab in adulthood cancers is more common, experience in childhood has been increasing recently. Herein, pediatric cases received nivolumab for distinct cancers are presented. The data of nine patients under the age of 18 years who received nivolumab for various cancers in the Pediatric Oncology clinic between January 2019-December 2022 were obtained. Nivolumab was administered intravenously at a dose of 3 mg/kg with 30 minutes infusion every t
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Correia, Pedro José, Florinda Gama, Teresa Saavedra, et al. "Changes in the concentration of organic acids in roots and leaves of carob-tree under Fe deficiency." Functional Plant Biology 41, no. 5 (2014): 496. http://dx.doi.org/10.1071/fp13204.

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Several fruit trees are able to cope with iron (Fe) deficiency when grown in calcareous soils in the Mediterranean region, although information regarding well adapted slow-growing species is scarce, and the mechanisms activated by these species are not described in the literature. A crucial issue related to tolerance is the need to transport Fe over relatively long distances inside the plant. To evaluate the possible role of organic acids in the movement of Fe in tolerant plants, we studied the concentration of low molecular weight organic acids in several organs of 1-year old carob plants gro
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25

Shao, Ruixin, Huifang Zheng, Shuangjie Jia, Yanping Jiang, Qinghua Yang, and Guozhang Kang. "Nitric Oxide Enhancing Resistance to PEG-Induced Water Deficiency is Associated with the Primary Photosynthesis Reaction in Triticum aestivum L." International Journal of Molecular Sciences 19, no. 9 (2018): 2819. http://dx.doi.org/10.3390/ijms19092819.

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Photosynthesis is affected by water-deficiency (WD) stress, and nitric oxide (NO) is a free radical that participates in the photosynthesis process. Previous studies have suggested that NO regulates excitation-energy distribution of photosynthesis under WD stress. Here, quantitative phosphoproteomic profiling was conducted using iTRAQ. Differentially phosphorylated protein species (DEPs) were identified in leaves of NO- or polyethylene glycol (PEG)-treated wheat seedlings (D), and in control seedlings. From 1396 unique phosphoproteins, 2257 unique phosphorylated peptides and 2416 phosphorylati
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26

Tseng, Y. F., J. Lin, M. Dai, and S. J. Kao. "Joint effect of freshwater plume and coastal upwelling on phytoplankton growth off the Changjiang River." Biogeosciences 11, no. 2 (2014): 409–23. http://dx.doi.org/10.5194/bg-11-409-2014.

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Abstract. The Changjiang (Yangtze) River discharges vast amount of unbalanced nutrients (dissolved inorganic nitrogen and phosphorus with N / P ratio > 80 in general) into the East China Sea in summer. To study nutrient dynamics and P-stress potential for phytoplankton, a cruise was conducted in the Changjiang plume during summer 2011. With 3-D observations of nutrients, chlorophyll a (Chl a), and bulk alkaline phosphatase activity (APA), we concluded that the Changjiang Diluted Water and coastal upwelling significantly influenced the horizontal and vertical heterogeneities of phytoplankton
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Tseng, Y. F., J. Lin, M. Dai, and S. J. Kao. "Joint effect of freshwater plume and coastal upwelling on phytoplankton growth off the Changjiang River." Biogeosciences Discussions 10, no. 6 (2013): 10363–97. http://dx.doi.org/10.5194/bgd-10-10363-2013.

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Abstract. Changjiang River discharges vast amount of unbalanced nutrients (dissolved inorganic nitrogen (N) and phosphorus (P) with N / P > 80 in general) into the East China Sea during summertime. To explore nutrient dynamics and P stress potential for phytoplankton, a cruise was conducted in the Changjiang plume during summer 2011. With 3-D observations of nutrients, chlorophyll a (Chl a), and bulk alkaline phosphatase activity (APA), we concluded that the Changjiang Diluted Water (CDW) and coastal upwelling significantly influenced the horizontal and vertical heterogeneities of phytoplan
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Kabashnikova, L. F., I. N. Domanskaya, T. S. Pilipovich, et al. "Photosynthetic pigments content and parameters of oxidative stress in the amaranth species with increasing water deficiency." Proceedings of the National Academy of Sciences of Belarus, Biological Series 66, no. 3 (2021): 282–94. http://dx.doi.org/10.29235/1029-8940-2021-66-3-282-294.

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The dynamics of the photosynthetic pigments content and parameters of oxidative stress with an increasing water deficit in the leaves of 40-days-old plants of two amaranth species - Amaranthus paniculatus L. (cv. Rubin) and Amaranthus caudatus L. (cv. Chyrvony aksamit), grown in a pot culture, was studied. Specific features of the development of water deficiency in amaranth leaves were revealed: amaranth plants Amaranthus paniculatus L. showed a stronger development of water deficit in leaves than Amaranthus caudatus L. after 4-days soil drought, which after 8 days increased in two species to
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29

Wójtowicz, Joanna, Adam K. Jagielski, Agnieszka Mostowska, and Katarzyna B. Gieczewska. "Compensation Mechanism of the Photosynthetic Apparatus in Arabidopsis thaliana ch1 Mutants." International Journal of Molecular Sciences 22, no. 1 (2020): 221. http://dx.doi.org/10.3390/ijms22010221.

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The origin of chlorophyll b deficiency is a mutation (ch1) in chlorophyllide a oxygenase (CAO), the enzyme responsible for Chl b synthesis. Regulation of Chl b synthesis is essential for understanding the mechanism of plant acclimation to various conditions. Therefore, the main aim of this study was to find the strategy in plants for compensation of low chlorophyll content by characterizing and comparing the performance and spectral properties of the photosynthetic apparatus related to the lipid and protein composition in four selected Arabidopsis ch1 mutants and two Arabidopsis ecotypes. Muta
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30

Xu, Keren, Niquelle B. Wadé, Amie E. Hwang, et al. "Whole-Exome Sequencing in Multiplex Families to Identify Novel AYA Classical Hodgkin Lymphoma Predisposition Genes." Blood 138, Supplement 1 (2021): 3499. http://dx.doi.org/10.1182/blood-2021-153247.

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Abstract Background: Hodgkin Lymphoma (HL) is a B-cell malignancy that mainly affects young adults in economically developed countries. Classical HL (cHL) is the most common type, comprising >95% of cases. We demonstrated strong heritability of cHL in adolescents and young adults (AYA) with a high risk to the unaffected co-twins of affected monozygotic (MZ) twins. We and others identified common risk variants by GWAS, and sequencing of familial and sporadic HL patients previously identified rare pathogenic germline variants in genes with varying functions. Few have replicated in other f
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31

Zhang, Ke, Xiaojun Liu, Yong Ma, et al. "A Comparative Assessment of Measures of Leaf Nitrogen in Rice Using Two Leaf-Clip Meters." Sensors 20, no. 1 (2019): 175. http://dx.doi.org/10.3390/s20010175.

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Accurate estimation and monitoring of crop nitrogen can assist in timely diagnosis and facilitate necessary technical support for fertilizer management. Four experiments, involving three cultivars and six nitrogen (N) treatments, were conducted in southeast China to compare the two leaf-clip meters (Dualex 4 Scientific+, Force-A, Orasy, France; Soil and Plant Analyzer Development (SPAD) meter, Minolta Camera Co., Osaka, Japan) for their ability to measure nitrogen nutrient-related indicators. The results indicated that Chl had a better monitoring accuracy for chlorophyll in per unit leaf area
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Ogawa, Takako, and Kintake Sonoike. "Effects of Bleaching by Nitrogen Deficiency on the Quantum Yield of Photosystem II inSynechocystissp. PCC 6803 Revealed by Chl Fluorescence Measurements." Plant and Cell Physiology 57, no. 3 (2016): 558–67. http://dx.doi.org/10.1093/pcp/pcw010.

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33

Ramírez, Librada, Leonardo J. Pozzo-Pirotta, Aja Trebec, et al. "Ocean alkalinity enhancement (OAE) does not cause cellular stress in a phytoplankton community of the subtropical Atlantic Ocean." Biogeosciences 22, no. 7 (2025): 1865–86. https://doi.org/10.5194/bg-22-1865-2025.

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Abstract. A natural plankton community from oligotrophic subtropical waters of the Atlantic near Gran Canaria, Spain, was subjected to varying degrees of ocean alkalinity enhancement (OAE) to assess the potential physiological effects in the context of the application of ocean carbon dioxide removal (CDR) techniques. We employed nine mesocosms with sediment traps attached to the bottom, each enclosing a volume of 8.3 m3, to create a gradient in total alkalinity (TA). OAE was based on the addition of carbonates (NaHCO3 and Na2CO3). The lowest point on this gradient was 2400 µmol L−1, which corr
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34

Urosevic, Jelena, James T. Lynch, Stefanie Meyer, et al. "Epigenetic Silencing of MTAP in Hodgkin's Lymphoma Renders It Sensitive to a 2 nd Generation PRMT5 Inhibitor." Blood 142, Supplement 1 (2023): 4185. http://dx.doi.org/10.1182/blood-2023-174445.

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Background: PRMT5 is type II arginine methyltransferase that catalyses symmetric dimethylation of arginine residues (SDMA) and plays an important role in cancer biology. By methylating a number of substrates, PRMT5 can regulate important processes such as DNA repair, RNA splicing, and cellular proliferation. In addition, PRMT5 is overexpressed in various cancer types and has been identified as a candidate for therapeutic intervention through the development of small molecules that inhibit PRMT5 methyltransferase activity. However, first generation PRMT5 inhibitors have shown limited clinical b
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35

Herrmann, Brian William, Campbell R. Hathaway, and Michael Fadell. "Hearing Loss in Pediatric Septo-Optic Dysplasia." Annals of Otology, Rhinology & Laryngology 128, no. 6 (2019): 485–89. http://dx.doi.org/10.1177/0003489419832629.

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Objective: To identify and characterize hearing loss (HL) in children with septo-optic dysplasia (SOD). Methods: Otologic and audiometric data for patients less than 18 years of age identified as having SOD who were seen in the Children’s Healthcare of Atlanta-Scottish Rite Hospital clinic between 2013 and 2017 were collected and reviewed through a HIPAA-compliant medical record search. Relevant literature was also reviewed with the assistance of Medline. Results: Sixty-four patients with SOD were identified, and 7 of those patients (10.9%) were diagnosed with hearing loss. Type of hearing los
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36

Saleem, Ammara, Asma Zulfiqar, Baber Ali, Manal Ahmed Naseeb, Arwa Saad Almasaudi, and Steve Harakeh. "Iron Sulfate (FeSO4) Improved Physiological Attributes and Antioxidant Capacity by Reducing Oxidative Stress of Oryza sativa L. Cultivars in Alkaline Soil." Sustainability 14, no. 24 (2022): 16845. http://dx.doi.org/10.3390/su142416845.

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Rice ranks second among cereals in dietary uses around the world. Rice is deficient in iron (Fe), and these are important micronutrients for infants, men, and women. Fortification of rice with iron would help to minimize nutrient deficiency disorders among humans. The current study aims to introduce nutrient-rich rice. The effects of iron on germination, growth, photosynthetic pigment, antioxidant activity, and reduction of oxidative stress were investigated in four Oryza sativa L. cultivars. O. sativa of four different cultivars (Basmati-515, PK-386, KSK-133, and Basmati-198) were grown under
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37

Wienand, Kirsty, Bjoern Chapuy, Chip Stewart, et al. "Comprehensive Genomic Analysis of Flow-Sorted Hodgkin Reed Sternberg Cells Reveals Additional Genetic Bases of Immune Evasion." Blood 132, Supplement 1 (2018): 1559. http://dx.doi.org/10.1182/blood-2018-99-118453.

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Abstract Classical Hodgkin lymphoma (cHL) is composed of rare malignant Hodgkin Reed Sternberg (HRS) cells within an extensive, but ineffective, inflammatory/immune cell infiltrate. Emerging data suggests that cHLs use multiple genetic mechanisms to evade immune recognition. We previously found that HRS cells exhibit near-universal somatic copy number alterations (SCNAs) involving chromosome 9p24.1/PD-1-L1/PD-L2 and rare chromosomal rearrangements of PD-L1 or PD-L2. The 9p24.1 amplicon also includes JAK2, which increases JAK2 copy numbers, augments JAK2/STAT signaling and further induces PD-1
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38

Sayala, Hazem A., Sheila J. O’Connor, Andrew S. Jack, Chetan Patalappa, Peter Hillmen, and Roger G. Owen. "EBV Related Transformation Events in CLL." Blood 108, no. 11 (2006): 4963. http://dx.doi.org/10.1182/blood.v108.11.4963.4963.

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Abstract Less than 5% of patients with CLL undergo histological transformation to diffuse large B cell lymphoma (DLBL) while transformation to Classical Hodgkins lymphoma (CHL) is also recognised. It has been assumed that such events reflect genetic changes in the CLL clone but there is now emerging evidence to suggest that at least some transformation events may be Epstein Barr virus (EBV) related neoplasms not clonally related to CLL. In this analysis we have reviewed the clinical and laboratory features of 15 CLL patients with biopsy proven histological transformation to DLBL and 2 patients
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39

Puglisi, Fabrizio, Enrico La Spina, Alessandro Barbato, et al. "An Integrative Unbiased Global Analysis of the Metabolic Adaptive Response to Tryptophan Deprivation in Classical Hodgkin Lymphoma." Blood 136, Supplement 1 (2020): 26–27. http://dx.doi.org/10.1182/blood-2020-139748.

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Background Tryptophan (trp) is an essential aminoacid, required for de novo NAD+ synthesis. Our previous work showed that the microenvironment in classical Hodgkin Lymphoma is characterized by dysfunctional neutrophils and myeloid derived suppressor cells that produce a trp-degrading enzyme indoelamine deoxygenase (IDO-1), lowering the amount of trp. Aims To detect metabolomics changes in human cHL cell lines exposed in vitro to tryptophan deprivation, an amino acid involved in immune dysregulation and generation of anergic and tolerogenic T- cells. Methods In order to better understand the im
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40

Xie, Wei, Peng He, Hongliang Ma, Xiulan Huang, Gaoqiong Fan, and Hongkun Yang. "Straw Mulching Combined with Phosphorus Fertilizer Increases Fertile Florets of Wheat by Enhancing Leaf Photosynthesis and Assimilate Utilization." Agronomy 13, no. 9 (2023): 2342. http://dx.doi.org/10.3390/agronomy13092342.

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Lack of soil moisture and phosphorus deficiency limits wheat grain yield in dryland areas. However, the moisture-conserving effect of straw mulching combined with phosphor fertilization on fertile florets per spike (FFS) and grain yield remains unclear. During the 2020–2021 and 2021–2022 growing seasons, we investigated the combined effects of straw mulching (0 and 8000 kg ha−1) and phosphorus fertilization (0, 75, and 120 kg P2O5 ha−1) on spike development, assimilates’ availability, and the photosynthetic properties of flag leaves by conducting a field experiment. Compared with no straw mulc
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41

Edwards, GE, and CLD Jenkins. "C4 Photosynthesis: Activities of Photosynthetic Enzymes in a Virescent Mutant of Maize Having a Low-Temperature Induced Chloroplast Ribosome Deficiency." Functional Plant Biology 15, no. 3 (1988): 385. http://dx.doi.org/10.1071/pp9880385.

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A virescent mutant of maize (v16/v16), which has a low temperature induced deficiency in 70S ribosomes, was used to examine whether the enzymes of the C4 pathway and other photosynthetic enzymes are synthesised on chloroplast ribosomes. The mutant and control plants were grown at 20°C and 30°C and the rates of photosynthesis and enzyme activities were compared. There was no photosynthesis in v16/v16 grown at 20°C (pale yellow), while plants grown at 30°C (normal green) had rates equivalent to the wild type and normal enzyme activities. On a leaf area basis, with v16/v16 grown at 20°C, the acti
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42

Puglisi, Fabrizio, Antonella Padella, Nunziatina Laura Parrinello, et al. "Dissecting the Adaptive Response to Arginine Deprivation in Hodgkin Lymphoma." Blood 138, Supplement 1 (2021): 4497. http://dx.doi.org/10.1182/blood-2021-151006.

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Abstract Background In Hodgkin Lymphoma (HL), neoplastic cells orchestrate an inflammatory microenvironment leading to sterile inflammation, T-cell anergy, and immune deficiency. Our group showed that in HL patients the aminoacid degrading enzyme Arginase-1 is increased, associated with poor outcome, and leads to arginine (Arg) deprivation. However, how the reduction of Arg in the extracellular milieu of the tumor microenvironment can contribute to neoplastic cell fitness is largely unknown. Aims To detect the adaptive response (via evaluation of global transcriptome and metabolome changes) in
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43

El-Yazied, Ahmed Abou, Mohamed F. M. Ibrahim, Mervat A. R. Ibrahim, et al. "Melatonin Mitigates Drought Induced Oxidative Stress in Potato Plants through Modulation of Osmolytes, Sugar Metabolism, ABA Homeostasis and Antioxidant Enzymes." Plants 11, no. 9 (2022): 1151. http://dx.doi.org/10.3390/plants11091151.

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The effect of melatonin (MT) on potato plants under drought stress is still unclear in the available literature. Here, we studied the effect of MT as a foliar application at 0, 0.05, 0.1, and 0.2 mM on potato plants grown under well-watered and drought stressed conditions during the most critical period of early tuberization stage. The results indicated that under drought stress conditions, exogenous MT significantly (p ≤ 0.05) improved shoot fresh weight, shoot dry weight, chlorophyll (Chl; a, b and a + b), leaf relative water content (RWC), free amino acids (FAA), non-reducing sugars, total
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44

Alexanin, Anatoly, Vasilii Kachur, Anastasiya Khramtsova, and Tatiana Orlova. "Methodology and Results of Satellite Monitoring of Karenia Microalgae Blooms, That Caused the Ecological Disaster off Kamchatka Peninsula." Remote Sensing 15, no. 5 (2023): 1197. http://dx.doi.org/10.3390/rs15051197.

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The environmental disaster in Kamchatka in the autumn of 2020 was caused by an extensive bloom of harmful microalgae of the genus Karenia. A spectral shape algorithm was used to detect algae on satellite imagery. The algorithm calibration of in situ species composition data made it possible to identify areas where harmful algae dominated in biomass. The algorithm allowed evaluation of the dynamics of the distribution of the algae. The state of phytoplankton was estimated based on images of the specific capacity of photosynthesis. Specific fluorescence is the ratio of the height of the fluoresc
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45

Leblanc, K., C. E. Hare, Y. Feng, et al. "Distribution of calcifying and silicifying phytoplankton in relation to environmental and biogeochemical parameters during the late stages of the 2005 North East Atlantic Spring Bloom." Biogeosciences Discussions 6, no. 3 (2009): 5789–847. http://dx.doi.org/10.5194/bgd-6-5789-2009.

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Abstract. The late stage of the North East Atlantic (NEA) spring bloom was investigated during June 2005 along a transect section from 45 to 66° N between 15 and 20° W in order to characterize the contribution of siliceous and calcareous phytoplankton groups and describe their distribution in relation to environmental factors. We measured several biogeochemical parameters such as nutrients, surface trace metals, algal pigments, biogenic silica (BSi), particulate inorganic carbon (PIC) or calcium carbonate, particulate organic carbon, nitrogen and phosphorus (POC, PON and POP, respectively), as
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46

Naz, Arshi, Tehmina nafees sonia Khan, Noman A. Malik, Shahla Tariq, Nazish Saqlain, and Tahir Shamsi. "Characterization of Phenotypic Expression of Inherited Fibrinogen Coagulopathy in Pakistani Index Patients." Blood 126, no. 23 (2015): 4667. http://dx.doi.org/10.1182/blood.v126.23.4667.4667.

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Abstract Background: Congenital afibrinogenemia is inherited as an autosomal recessive trait and consanguinity is common among affected families. Phenotypic expression of this particular factor deficiency is still not unanimously established in research literature globally as the disease manifests with variability in symptoms which may ranges from minimal bleeding to catastrophic hemorrhage. Aim: To characterize the clinical manifestations of patients to set a standard parameter of bleeding severity in our local population. Materials and Methods: This descriptive and cross sectional study was
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47

Grovenstein, Phillip B., Darryel A. Wilson, Kathryn D. Lankford, Kelsey A. Gaston, Surangi Perera, and Mautusi Mitra. "Identification and molecular characterization of a Chlamydomonas reinhardtii mutant that shows a light intensity dependent progressive chlorophyll deficiency." F1000Research 2 (June 19, 2013): 142. http://dx.doi.org/10.12688/f1000research.2-142.v1.

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The green micro-alga Chlamydomonas reinhardtii is an elegant model organism to study all aspects of oxygenic photosynthesis. Chlorophyll (Chl) and heme are major tetrapyrroles that play an essential role in energy metabolism in photosynthetic organisms. These tetrapyrroles are synthesized via a common branched pathway that involves mainly nuclear encoded enzymes. One of the enzymes in the pathway is Mg chelatase (MgChel) which inserts Mg2+ into protoporphyrin IX (PPIX, proto) to form Magnesium-protoporphyrin IX (MgPPIX, Mgproto), the first biosynthetic intermediate in the Chl branch. The GUN4
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48

Tian, Yunlong, Jingjing Xu, Linxin Li, Taimoor Hassan Farooq, Xiangqing Ma, and Pengfei Wu. "Effect of arbuscular mycorrhizal symbiosis on growth and biochemical characteristics of Chinese fir (Cunninghamia lanceolata) seedlings under low phosphorus environment." PeerJ 12 (March 22, 2024): e17138. http://dx.doi.org/10.7717/peerj.17138.

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Background The continuous establishment of Chinese fir (Cunninghamia lanceolata) plantations across multiple generations has led to the limited impact of soil phosphorus (P) on tree growth. This challenge poses a significant obstacle in maintaining the sustainable management of Chinese fir. Methods To investigate the effects of Arbuscular mycorrhizal fungi (AMF) on the growth and physiological characteristics of Chinese fir under different P supply treatments. We conducted an indoor pot simulation experiment in the greenhouse of the Forestry College of Fujian Agriculture and Forestry Universit
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49

Cisternas-Novoa, Carolina, Frédéric A. C. Le Moigne, and Anja Engel. "Composition and vertical flux of particulate organic matter to the oxygen minimum zone of the central Baltic Sea: impact of a sporadic North Sea inflow." Biogeosciences 16, no. 4 (2019): 927–47. http://dx.doi.org/10.5194/bg-16-927-2019.

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Abstract. Particle sinking is a major form of transport for photosynthetically fixed carbon to below the euphotic zone via the biological carbon pump (BCP). Oxygen (O2) depletion may improve the efficiency of the BCP. However, the mechanisms by which O2 deficiency can enhance particulate organic matter (POM) vertical fluxes are not well understood. Here, we investigate the composition and vertical fluxes of POM in two deep basins of the Baltic Sea (GB: Gotland Basin and LD: Landsort Deep). The two basins showed different O2 regimes resulting from the intrusion of oxygen-rich water from the Nor
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50

Pánisová, Elena, Anna Lünemann, Simone Bürgler, et al. "Reduced frequency of cytotoxic CD56dim CD16+ NK cells leads to impaired antibody-dependent degranulation in EBV-positive classical Hodgkin lymphoma." Cancer Immunology, Immunotherapy, May 15, 2021. http://dx.doi.org/10.1007/s00262-021-02956-x.

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AbstractAround 30–50% of classical Hodgkin lymphoma (cHL) cases in immunocompetent individuals from industrialized countries are associated with the B-lymphotropic Epstein-Barr virus (EBV). Although natural killer (NK) cells exhibit anti-viral and anti-tumoral functions, virtually nothing is known about quantitative and qualitative differences in NK cells in patients with EBV+ cHL vs. EBV- cHL. Here, we prospectively investigated 36 cHL patients without known immune suppression or overt immunodeficiency at diagnosis. All 10 EBV+ cHL patients and 25 out 26 EBV- cHL were seropositive for EBV ant
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