Academic literature on the topic 'Chlorhexidine gluconate'

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Journal articles on the topic "Chlorhexidine gluconate"

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Rubin, Caroline, Rufina Bavin Louthan, Erica Wessels, Mary-Bridgid McGowan, Shantee Downer, and Jeanne Maiden. "Chlorhexidine Gluconate." Critical Care Nursing Quarterly 36, no. 2 (2013): 233–36. http://dx.doi.org/10.1097/cnq.0b013e31828404d1.

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Basrani, Bettina. "Chlorhexidine Gluconate." Australian Endodontic Journal 31, no. 2 (August 2005): 48–52. http://dx.doi.org/10.1111/j.1747-4477.2005.tb00221.x.

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Kumar, G. Vinay, Veerendra Uppin, and Arvind Shenoy. "Comparison of Antibacterial Effects of Various Root Canal Irrigants on Enterococcus faecalis." World Journal of Dentistry 2, no. 3 (2011): 211–15. http://dx.doi.org/10.5005/jp-journals-10015-1085.

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ABSTRACT Aims To compare the antibacterial effects of various root canal irrigants against E.faecalis. Irrigants tested were 5.25% NaOCl, 0.2% chlorhexidine gluconate, and 0.2% cetrimide individually and combined. Materials and methods Root canal preparation was performed on 120 extracted permanent maxillary central and lateral incisor teeth. Following root canal preparation, apical foramina were sealed with epoxy resin to prevent bacterial leakage. The root canals were then contaminated with Enterococcus faecalis. After incubation, the contaminated roots were divided into four groups of 30 each. 2 mm of irrigant was delivered which remained in the canal for 10 minutes. The canals were then irrigated with 1 ml saline solution and with size 45 sterile paper point bacteria were sampled. The growth of E. faecalis which occurred in the tubes was inoculated onto blood agar plates. Statistical analysis Difference between the antibacterial efficacies of irrigants was evaluated statistically using chi-square test. Results There was no significant difference between the antibacterial efficacies of 0.2% chlorhexidine gluconate alone and 0.2% chlorhexidine gluconate with 0.2% cetrimide, but both had a significantly lower antibacterial effect than 5.25% sodium hypochlorite and 5.25% sodium hypochlorite with 0.2% chlorhexidine gluconate. This difference was statistically significant. Conclusions Within limitations of this study, it was concluded that the 5.25% sodium hypochlorite and 5.25% sodium hypochlorite with 0.2% chlorhexidine gluconate had a higher antibacterial effect than 0.2% chlorhexidine gluconate alone and 0.2% chlorhexidine gluconate with cetrimide. There was no significant difference between the antibacterial efficacies of 0.2% chlorhexidine gluconate alone and 0.25% chlorhexidine with certrimide.
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PATTON, DOROTHY L., YVONNE T. COSGROVE SWEENEY, TAMYRA L. McKAY, SHAUNE M. DeMERS, AGNES M. CLARK, LORNA K. RABE, and SHARON L. HILLIER. "0.25% Chlorhexidine Gluconate Gel." Sexually Transmitted Diseases 25, no. 8 (September 1998): 421–24. http://dx.doi.org/10.1097/00007435-199809000-00007.

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Noviyanti, Amalia, I. Wayan Arya Krishnawan Firdaus, and Rahmad Arifin. "THE EFFECT OF IRONWOOD STEM BARK EXTRACT (Eusideroxylon zwageri) ON THE GROWTH OF Streptococcus mutans ON ACRYLIC RESIN DENTURE PLATE." Dentino : Jurnal Kedokteran Gigi 6, no. 1 (May 11, 2021): 13. http://dx.doi.org/10.20527/dentino.v6i1.10634.

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ABSTRACTBackground: Streptococcus mutans is plaque-forming initiator bacteria. Plaque on the surface base of denture can cause color changing, bad breath, inflammation, and infection called denture stomatitis. Denture hygiene must be maintained by denture soaking in 0.2% chlorhexidine gluconate. However, 0.2% chlorhexidine gluconatethat used incessantly can cause side effects such as the changing of denture color and the fading of denture base pigmentation. The ironwood stem bark extract can be an alternative for denture cleanser material. Objectives: To analyze the effect of ironwood stem bark extract on the growth of Streptococcus mutans on heat cured type acrylic resin denture plate. Methods: True experimental laboratories research was used with post test only control group design using 9 treatment groups which are 5%, 10%, 20%, 40%, 60%, 80%, 100% concentration of ironwood stem bark extract, 0.2% chlorhexidine gluconate and aquadest. The treatment was performed with 3 times repetition resulting in 27 total samples. Antibacterial activity was measured by calculating the bacteria colony number. Results: The 5% and 10% concentration of ironwood stem bark extract were effective in reducing Streptococcus mutans with30.3 CFU/ml and 10.3 CFU/ml average colony number. The ironwood stem bark extracts with 20%, 40%, 60%, 80%, 100% concentration are effective and equivalent to 0.2% chlorhexidine gluconate against Streptococcus mutans with 0 CFU/ml average value. Conclusion: The 20%, 40%, 60%, 80%, 100% concentration of ironwood stem bark extract is equally effective as 0.2% chlorhexidine gluconatein killing Streptococcus mutans,exhibiting potential to be an alternative for denture cleanser material.Keyword: 0.2% Chlorhexidine gluconate, ironwood stem bark extract, acrylic resin denture plate heat cured type, Streptococcus mutans.
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Ummah, Afin Aslihatul, Laksmiari Setyowati, and Ketut Suardita. "Cytotoxicity test of 0,78% xanthone from mangosteen pericarp (Garcinia mangostana L.) and 0,2% chlorhexidine gluconate toward BHK-21 fibroblast cells." Conservative Dentistry Journal 10, no. 2 (June 30, 2020): 54. http://dx.doi.org/10.20473/cdj.v10i2.2020.54-57.

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Background. Chlorhexidine gluconate is one of endodontic irrigants that has excellence capability to penetrate into dentin tubules and kill the pathogenic bacteria there. On the other hand, chlorhexidine gluconate has side effects to cause allergic reactions of the tissue and discoloration of the teeth. Xanthone from mangosteen pericarp can be considered as a natural alternative irrigant that usually has a good tolerance to the body. Purpose. The aim of this study compared the cytotoxicity between 0,78% xanthone from mangosteen pericarp and 0,2% chlorhexidine gluconate toward BHK-21 fibroblast cells. Methods. This study used experimental post-test only control group design. Xanthone from mangosteen pericarp preliminary cytotoxicity tested in various concentrations. Xanthone from mangosteen pericarp classified as a non-toxic concentration at 0,78%. Cytotoxicity of 0,78% xanthone from mangosteen pericarp compare with cytotoxicity of 0,2% chlorhexidine gluconate using MTT assay method. Cytotoxicity of material can be seen from % of cell viability. Viable cell measured by the result of optical density that read by ELISA reader 620 nm. Result. 0,78% xanthone from mangosteen pericarp showed lower cytotoxicity than 0,2% chlorhexidine gluconate toward BHK-21fibroblast cells. One-way ANOVA showed a significant difference between the study groups (P<0,05). Conclusion. 0,78% xanthone from mangosten pericarp showed lower cytotoxicity than 0,2% chlorhexidine gluconate toward BHK-21 fibroblast cells.
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Bhende, Shubhangi, and Daniel Spangler. "In Vitro Assessment of Chlorhexidine Gluconate–Impregnated Polyurethane Foam Antimicrobial Dressing Using Zone of Inhibition Assays." Infection Control & Hospital Epidemiology 25, no. 8 (August 2004): 664–67. http://dx.doi.org/10.1086/502458.

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AbstractObjective:To evaluate an antimicrobial dressing consisting of hydrophilic polyurethane foam with chlorhexidine gluconate for activity against several antibiotic-resistant clinical isolates as well as American Type Culture Collection reference strains using zone of inhibition assays.Methods:Sterile foam samples with chlorhexidine gluconate and untreated controls were transferred onto inoculated agar plates. Plates were incubated at 35°C to 37° C for 24 hours and examined for zones of inhibition around the foam samples.Results:Polyurethane foam with chlorhexidine gluconate showed antimicrobial activity in vitro against all of the challenge organisms including antibiotic-resistant clinical isolates.Conclusion:The data from this in vitro study support the hypothesis that polyurethane foam with chlorhexidine gluconate has an antimicrobial effect against antibiotic-resistant Staphylococcus and Enterococcus species, as well as Candida species.
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Khan, Mohammad, Zeehaida Mohamed, Saedah Ali, Norkhafizah Saddki, Sam’an Malik Masudi, and Ninin Sukminingrum. "Oral Care Effect on Intubated Patient with 0.2 per cent Chlorhexidine Gluconate and Tooth Brushing in Intensive Care Unit." Journal of Advanced Oral Research 8, no. 1-2 (May 2017): 26–33. http://dx.doi.org/10.1177/2229411217729099.

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Aims and Objectives: Ventilator-associated pneumonia is associated with increased morbidity and mortality. The aim of this pilot study was to determine the effectiveness of oral care with both tooth brushing and 0.2 per cent chlor-hexidine gluconate compared to 0.2 per cent chlorhexidine gluconate alone for the intubated patient in an intensive care unit (ICU). Materials and Methods: Patient screening was done over a period of two months. After taking informed consent, those ICU patients were divided into two groups. Only nine subjects were enrolled. During the study, the experimental group (N = 4) got oral care that consisted of both tooth brushing and 0.2 per cent chlorhexidine gluconate thrice a day. The control group got oral care with 0.2 per cent chlorhexidine gluconate alone thrice a day. The data were analysed by IBM statistical software SPPS, version 24. Results: Preliminary results suggest that the risk of ventilator-associated pneumonia in intubated patients can be reduced by maintaining thrice-daily oral care involving both tooth brushing and 0.2 per cent chlorhexidine gluconate. Conclusion: Thrice-daily oral care consisted of both tooth brushing and 0.2 per cent chlorhexidine gluconate might be a promise as a ventilator-associated pneumonia-reduction strategy in ICU. Furthermore, more studies are required for its application widely.
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Chapman, Leigh, Lisa Hargett, Theresa Anderson, Jacqueline Galluzzo, and Paul Zimand. "Chlorhexidine Gluconate Bathing Program to Reduce Health Care–Associated Infections in Both Critically Ill and Non–Critically Ill Patients." Critical Care Nurse 41, no. 5 (October 1, 2021): e1-e8. http://dx.doi.org/10.4037/ccn2021340.

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Background Critical care nurses take care of patients with complicated, comorbid, and compromised conditions. These patients are at risk for health care–associated infections, which affect patients’ lives and health care systems in various ways. Objective To gauge the impact of routinely bathing patients with 4% chlorhexidine gluconate solution on the incidence of health care–associated infections in a medical-surgical intensive care unit and a postoperative telemetry unit; to outline the framework for a hospital-wide presurgical chlorhexidine gluconate bathing program and share the results. Methods A standard bathing protocol using a 4% chlorhexidine gluconate solution was developed. The protocol included time studies, training, monitoring, and surveillance of health care–associated infections. Results Consistent patient bathing with 4% chlorhexidine gluconate was associated with a 52% reduction in health care–associated infections in a medical-surgical intensive care unit. The same program in a postoperative telemetry unit yielded a 45% reduction in health care–associated infections. Conclusion A comprehensive daily 4% chlorhexidine gluconate bathing program can be implemented with standardized protocols and detailed instructions and can significantly reduce the incidence of health care–associated infections in intensive care unit and non–intensive care unit hospital settings.
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Dwipriastuti, Devi, R. Rama Putranto, and Welly Anggarani. "PERBEDAAN EFEKTIVITAS CHLORHEXIDINE GLUKONAT 0,2% DENGAN TEH HIJAU (CAMELLIA SINENSIS) TERHADAP JUMLAH PORPHYROMONAS GINGIVALIS." ODONTO : Dental Journal 4, no. 1 (July 1, 2017): 50. http://dx.doi.org/10.30659/odj.4.1.50-54.

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Background: Periodontitis is a periodontal inflammation caused by plaque that contains pathogens, Porphyromonas gingivalis is one of them. Chlorhexidine therapy used to reduce the number of pathogenic bacteria causing periodontitis. Green tea contains polyphenols such as epigallocatechin-3-gallic as antibacterial agent that can kill the bacteria Porphyromonas gingivalis. This study aims to determine differences in the effectiveness of chlorhexidine gluconate 0.2% with green tea (Camellia sinensis) various concentrations to decrease the amount of bacteria Porphyromonas gingivalis.Method: This research was experimental with post test only design. Method used in antibacterial test was a drop plate misra. The experimental group consisted of six groups: chlorhexidine gluconate 0.2% and green tea group with a concentration of 100%, 75%, 50%, 25% and 12.5%. minimum bactericidal concentrations againts Porphyromonas gingivalis was evidenced by counting the number of colonies that formed on agar. Analysis data was using One Way ANOVA continued by Post hoc tests Tamhane.Result: The results showed that chlorhexidine gluconate 0.2% with green tea effective to decrease the amount of bacteria Porphyromonas gingivalis(ANOVA p <0.05). The results between the groups showed green tea 100%, 75% and 25%, have same effect compared to chlorhexidine gluconate 0.2% in reducing Porphyromonas gingivalis.Conclusion: In this experiment showed that chlorhexidine gluconate 0.2% and green tea extract 100%, 75%, 50%, 25% and 12.5% were able to decrease the amount of Porphyromonas gingivalis.
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Dissertations / Theses on the topic "Chlorhexidine gluconate"

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Atbayga, Abdalla Mohammed Ali. "In vitro anti-bacterial activity of titanium oxide nano-composites containing benzalkonium chloride and chlorhexidine gluconate." Thesis, Cape Peninsula University of Technology, 2013. http://hdl.handle.net/20.500.11838/1460.

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Thesis submitted in fulfilment of the requirements for the degree Master of Technology: Biomedical Technology In the Faculty of Health and Wellness Sciences At Cape Peninsula University of Technology 2013
Newly developed and commercial dental resins which are commonly used nowadays have to be tested for their antimicrobial susceptibility. The purpose of this in vitro study was to investigate the antimicrobial activity of a titanium oxide (TiO2) nano-composite which was prepared with different antibacterial substances and used as restoratives in dentistry to combat certain selected bacteria that are considered the principle causes of some tooth diseases, for example, tooth decay and to prevent unsuccessful dental restoration. The TiO2 nano-composite was prepared and divided into four groups: The first group was an untreated TiO2 nano-composite. The second group was silane-treated TiO2 nano-composite. The third group was treated TiO2 nano-composite which was combined with chlorhexidine gluconate (CHxG). The fourth group was treated TiO2 nano-composite which was combined with benzalkonium chloride (BzCl). Five of the selected bacteria were grown overnight in Petri dishes. Four of them, namely, Escherichia coli (E. coli) ATCC 11775, Staphylococcus aureus (S. aureus) ATCC 12600, Enterococcus faecalis (E. faecalis) ATCC 29212, and Pseudomonas aeruginosa (P. aeruginosa) ATCC 10145, were grown on Müller-Hinton Agar (MHA). Streptococcus mutans (S. mutans) ATCC 25175 was grown on Brain Heart Infusion (BHI) agar. All these bacteria were tested against the TiO2 nano-composite, and incubated for 24 hours at 37°C, except S. mutans, which was incubated separately and exposed to CO2. It was placed into a CO2 water-jacketed incubator in an atmosphere of 5% CO2 for 24 hours at 37°C. The obtained results showed that neither of the groups of TiO2 nano-composites, (untreated TiO2 nano-composite and treated TiO2 nano-composite) exhibited antimicrobial activity against the pathogens. Only preparations of TiO2 nano-composites at a concentration of 3 %m/m of both CHxG and BzCl showed antimicrobial activity against S. aureus. Antimicrobial activity against S. mutans, E. coli, P. aeruginosa, E. faecalis and S. aureus, were only realized at a concentration of 10 %m/m for both CHxG and BzCl..
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Ferguson, David B. "The Effect of Chlorhexidine Gluconate as an Endodontic Irrigant on the Apical Seal: Long-term Results." VCU Scholars Compass, 2003. http://scholarscompass.vcu.edu/etd/1408.

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The purpose of this study was to determine whether chlorhexidine gluconate (0.12%), used as an endodontic irrigating solution would affect the apical seal of three root canal cements. One hundred extracted human single-canal teeth were divided into 9 experimental groups of 10 teeth each, in addition to a positive and negative control group of 5 teeth each. The teeth were decoronated at the level of the cementoenamel junction, accessed, instrumented to a Master Apical File #50, irrigated with either sterile saline, 5.25% NaOCl or 0.12% chlorhexidine gluconate, and dried using paper points. Obturation was accomplished using lateral condensation and one of three endodontic sealers: Roth's 811, AH26, or Sealapex. Post-obturation apical leakage was measured at 270- and 360-day observation periods using the fluid filtration method. Using the mixed-model repeated-measures ANOVA test with Tukey's HSD multiple comparison procedure, the results showed the saline-Sealapex combination had significantly more leakage (p<0.05) than either the Peridex-Sealapex or saline-Roth's combinations at 270 days. No other significant differences were noted between any sealer-irrigant combination at 270 days. The saline-Sealapex combination had significantly more leakage than the saline-Roth's combination at 360 days. No other significant differences were noted at 360 days. Under the conditions of this study, chlorhexidine gluconate irrigant did not adversely affect the apical seal of three root canal cements at 270 and 360 days.
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Tatu, Rigwed R. "Effects of Aqueous Chlorhexidine Gluconate Exposure on Thermal, Mechanical and Chromatographic Properties of Polycarbonate and Polyether Urethanes." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1407408200.

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Chaiyakunapruk, Nathorn. "Meta-analysis and cost-effectiveness analyses of chlorhexidine gluconate and povidone iodine use for the prevention of catheter-related bloodstream infection /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/7946.

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Thiessen, Craig B. D. "Antibacterial efficacy of 0.12-percent and 2.0-percent chlorhexidine gluconate at 37° C and 46° C against Enterococcus faecalis." Connect to resource online, 2010. http://hdl.handle.net/1805/2226.

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Thesis (M.S.D.)--Indiana University School of Dentistry, 2010.
Title from PDF t. p. (viewed July 28, 2010) Advisor(s): Mychel Vail, Chair of the Research Committee, Richard Gregory, Joseph Legan, Kenneth Spolnik, Susan Zunt. Curriculum vitae. Includes abstract. Includes bibliographical references (leaves 108-120).
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Lai, Shuk-tin, and 黎淑鈿. "Evidence-based guidelines for chlorhexidine gluconate in preoperative skin preparation to reduce surgical site infection in patients undergoing general surgery." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193047.

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Surgical site infection not only brings morbidity and mortality to patients, but it also bring substantial financial burden to the hospital and the healthcare system. To minimize the clinical consequences of surgical site infection, it is crucial that all appropriate measures for reduction of surgical site infection should be implemented. Since patient’s skin is a potential source of pathogens, normal skin flora is a common cause of surgical site infections. Preoperative skin disinfection of the surgical site with an antiseptic agent is an effective method to remove the soil and transient organisms from the skin. Currently, there are different skin antiseptics available and the most commonly used agents are povidone iodine and chlorhexidine gluconate. Although povidone iodine has a long-standing recommendation and it is widely used in various surgical procedures, it has several limitations. On the other hand, there is an increasing interest of the use of chlorhexidine in indwelling catheter placement and care, surgical hand scrubbing, as well as wound dressing. In view of this, there is a potential of replacing povidone iodine by chlorhexidine as preoperative skin antiseptic agent. As there is no existing guideline supportingthis innovative movement, this dissertation aimed to review the currently available evidence on preoperative skin preparation and to develop an evidence-based guideline of using chlorhexidine in preoperative skin preparation for reducing surgical site infection in patients undergoing general surgery. Five randomized controlled studies were identified from MEDLINE, CINAHL and PUBMED and evaluated by a critical appraisal tool, the Scottish Intercollegiate Guidelines Network. All studies reported that preoperative skin preparation with chlorhexidine is more effective than the use of povidone iodine in reducing surgical site infection. An evidence-based guideline is developed according to the guideline development process from the Scottish Intercollegiate Guideline Network. Patient characteristics, local clinical setting, organizational infrastructure and staff competency is congruent with the proposed innovation. The new protocol not only can minimize the risk of postoperative surgical site infection but also save costs. The cost-benefit analysis showed that the new protocol can help to save $675,552 to $1,097,772 (HK dollars) in six-month period after implementation. To facilitate a more comprehensive plan in actual implementation of the proposed guideline, stakeholders at administrative, managerial, and operational levels would be invited to take part in the 12-week pilot test. Surgical site infection, staff satisfaction and compliance, as well as cost and benefit ratio of the guideline would be measured in the evaluation plan. The refined guidelines would then be implemented for one year. The effectiveness of the guideline would be determined by reduction in postoperative surgical site infection, increase in staff knowledge and satisfaction, and the overall expenditure.
published_or_final_version
Nursing Studies
Master
Master of Nursing
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Denny, Janette Echemendia. "The Effectiveness of an Intervention Designed to Improve Chlorhexidine (CHG) Bathing Technique in Adults Hospitalized in Medical Surgical Units." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6223.

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Central line associated bloodstream infections (CLABSIs) are one of the most fatal types of healthcare associated infections (HAIs) and their economic impact is significant. Although some studies have found no signification reduction in CLABSI rates with chlorhexidine gluconate (CHG) bathing; good evidence exists to support the use of CHG bathing as an intervention to reduce CLABSIs (Bleasdale et al., 2007; Climo et al., 2009; Climo et al., 2013; Montecalvo et al., 2012). CHG bathing performance may influence the effectiveness of the CHG bathing protocol. The purpose of this study was to determine the effect of a targeted educational approach involving simulation on the delivery by nursing assistants of a CHG bathing protocol. The study aims were (1) to compare the effectiveness of removal of simulated skin microbes by nursing assistants who receive training for a CHG bathing protocol with simulation training to simulated skin microbe removal by nursing assistants who receive training for a CHG bathing protocol without simulation training and (2) to examine the influence of a demographic factor, years of practice as a nursing assistant on the percentage of simulated microbes present following performance of bathing. Thirty nursing assitant volunteered for this study and were randomized to either the intervention group (training for a 2% CHG cloth bathing protocol with simulation training) or the control group (training for a 2% CHG cloth bathing protocol without simulation training). For aim (1) an independent t-test (inferential tests of group differences) was used to examine if there was any difference between the intervention group and the control group on the percentage of microbes remaining on the mannequin post bathing. For aim (2) a Pearson correlation was computed to assess the relationship between years of practice as a nursing assistant and the percentage of microbes remaining post bathing. Results showed no statistically significant differences between the two groups on demographc factors. For aim (1) the t-test revealed a statistically significant (p < .001) difference between the intervention group and the control group on the percentage of simulated microbes remaining on the mannequin post bathing. For aim (2) there was no correlation between the years of practice as a nursing assistant and the amount of microbes left on the mannequin post bathing (p=.709). This study provided an innovative method of assessing the percentage of simulation microbes remaining on the mannequin and made it possible to quantitatively measure bathing performance. Monitoring the compliance with CHG bathing is an important component when evaluating the effectiveness of a CHG bathing protocol. The findings of this study suggest that simulation training was an added benefit to the nursing assistants who received it, as they performed better than those who did not receive simulation training.
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Ito, Célia Regina Malveste. "A avaliação do efeito de antissépticos na superfície ocular e o papel da gentamicina no controle microbiano de córneas doadas." Universidade Federal de Goiás, 2017. http://repositorio.bc.ufg.br/tede/handle/tede/8115.

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Decontamination of the surface of the donor eyeballs is part of the operational norms that eye banks advocate before preservation, and antisepsis procedures are effective, ensuring greater transplantation safety. The objective of the present study was to evaluate the antiseptic effect in reducing the microbiota of the ocular globe of donors of corneas prior to enucleation, with 5% povidone-iodine (PVP-I) and 0.05% chlorhexidine gluconate (GC), In the action times of 5, 10 and 15 minutes, as well as the susceptibility profile of the microbiota isolated from gentamicin. Thirty pairs of corneas received antiseptics, with PVP-I in the right eye and GC in the left, and for each time of action 10 pairs of eyeballs were used. Swabs were collected from the ocular surface before application of the solutions, after and at the time of preservation of the corneal tissue, to evaluate the reduction of the microbiota. After identification of the microbiota, an antibiogram test was performed with gentamicin. The data were computed and evaluated by Chi-square or Fisher's exact test, T-test and McNemar test paired, and the statistical significance level was 5% (p <0.05). In the second collection, after antisepsis, there was a reduction of 39,5% in the total of gram positive bacteria (G +), and of 76,5% in the gram negative (G-) bacteria, with no statistically significant difference (p = 0.183), which demonstrated that the bacterial elimination capacity of the antiseptics was similar. It was observed that, in the second collection, both were more effective for G-, with a statistically significant difference (p <0.001), than for G +, with no statistically significant difference (p = 0.494). In the third collection, after the residual effect of the antiseptics, there was a reduction of 99.1% of all the microorganisms. In the antibiogram test, 88% of the isolated microorganisms were sensitive to gentamicin. It was concluded that the use of antiseptics is essential for the effective decontamination of donated corneas prior to preservation. The residual time of the antiseptics increased the decontamination power of PVP-I and GC, being similar in reducing the microbiota of the ocular globe of the donor of corneas. Gentamycin contained in the cornea preservation medium complements the antisepsis of the donated tissues.
A descontaminação da superfície dos globos oculares doados são normas operacionais que os bancos de olhos preconizam antes da preservação e os procedimentos de antissepsia são eficazes, garantindo uma maior segurança ao transplante. O objetivo do presente estudo foi avaliar o efeito antisséptico na redução da microbiota do globo ocular de doadores de córneas antes da enucleação, com o povidona-iodo (PVP-I) a 5% e gluconato de clorexidina (GC) a 0,05%, nos tempos de ação de 5, 10 e 15 minutos, bem como o perfil de susceptibilidade da microbiota isolada à gentamicina. Trinta pares de córneas receberam antissépticos, sendo o PVP-I no olho direito e o GC no esquerdo, e para cada tempo de ação foram utilizados 10 pares de globos oculares. Foram colhidos swabs da superfície ocular antes da aplicação das soluções, após e no momento da preservação do tecido corneano, para avaliar a redução da microbiota. Após identificação da microbiota, foi realizado teste de antibiograma com gentamicina. Os dados foram computados e avaliados pelos testes Qui-Quadrado ou Exato de Fisher, teste T e Teste McNemar pareado, e o nível de significância estatística foi (p<0,05). Com relação aos dados obtidos na segunda coleta, após o uso de antissépticos, houve uma redução de 39,5% no total de bactérias gram positivas (G+) e de 76,5% nas gram negativas (G-), não havendo diferença estatística significativa (p=0,183), sendo semelhante a capacidade de eliminação bacteriana dos antissépticos. Observa-se que, na segunda coleta, ambos foram mais eficazes para as G-, com diferença estatisticamente significativa (p<0,001), do que para as G+, sem diferença estatisticamente significativa (p=0,494). Na terceira coleta, após o efeito residual dos antissépticos, houve redução de 99,1% de todos os micro-organismos. No teste de antibiograma, 88% dos micro-organismos isolados foram sensíveis à gentamicina. Concluiu-se que o uso de antissépticos é essencial para a efetiva descontaminação das córneas doadas antes da preservação. O tempo residual dos antissépticos aumentou o poder de descontaminação do PVP-I e GC, sendo semelhantes na redução da microbiota do globo ocular do doador de córneas. A gentamicina contida no meio de preservação de córnea complementa a antissepsia dos tecidos doados.
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Stiles, Spencer R. "The effects on the antimicrobial properties of Hoshino's triple antibiotic paste when chlorhexidine gluconate (0.12%) is substituted for the propylene glycol and macrogol ointment mixture." Morgantown, W. Va. : [West Virginia University Libraries], 2010. http://hdl.handle.net/10450/11207.

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Thesis (M.S.)--West Virginia University, 2010.
Title from document title page. Document formatted into pages; contains v, 47 p. : col. ill. Includes abstract. Includes bibliographical references (p. 44-47).
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Asmyou, Sana Alhadi. "An in-vitro study of antifungal activity of gymnemic acid." University of the Western Cape, 2017. http://hdl.handle.net/11394/6239.

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Magister Chirurgiae Dentium - MChD (Oral Medicine and Periodontics)
Candida species are frequently isolated from oral mucosal surfaces of healthy individuals and is the most common genus responsible for up to 75% of all candidal infections. The most common problems associated management of oral candidiasis are antifungal drug resistance and side effects Natural medicine is an emerging field and is being explored to overcome drug resistance and to reduce side effects. Gymnemagenin (will be known as Gymnemic acid; GA) is a purified extract from Gymnema sylvestre, a slow growing, perennial, medicinal plant found in Central and Western India, Tropical Africa and Australia is regarded as one of the plants with potent antimicrobial and antifungal activity.
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Books on the topic "Chlorhexidine gluconate"

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Blokdijk, G. J. Chlorhexidine Gluconate ; Third Edition. CreateSpace Independent Publishing Platform, 2018.

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Paquette, Lisane. The effectiveness of chlorhexidine gluconate as an intracanal medication in endodontics: An in vivo microbiological study. 2004.

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Book chapters on the topic "Chlorhexidine gluconate"

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Buller, Megan, and Kyle J. Popovich. "Chlorhexidine Gluconate Bathing Outside the Intensive Care Unit." In Infection Prevention, 277–83. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60980-5_29.

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Paulson, Daryl. "Chlorhexidine Gluconate." In Handbook of Topical Antimicrobials. CRC Press, 2002. http://dx.doi.org/10.1201/9780203909256.ch6.

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Diaz-Gomez, Jose L., and Sarah W. Robison. "Nasopharyngeal and Oropharyngeal Decontamination to Prevent Nosocomial Infection in Cardiac Surgery Patients." In 50 Studies Every Intensivist Should Know, edited by Edward A. Bittner and Michael E. Hochman, 282–86. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190467654.003.0046.

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Preventing nosocomial infections is important to improve postoperative outcomes for cardiac surgery patients. The patient’s own flora is thought to be the primary source of potentially pathogenic bacteria. Therefore, decontamination is an appealing preventative strategy for reducing nosocomial infections. This study investigated the use of topical chlorhexidine gluconate for perioperative nasal and oropharyngeal decontamination in cardiac surgery patients. The intervention resulted in a significant reduction in lower respiratory tract infections, deep surgical site infections, use of nonprophylactic antibiotics, and duration of hospitalization. There was an absolute risk reduction in total nosocomial infection of 6.4%; 16 patients would have to be treated with the chlorhexidine decontamination strategy to prevent one nosocomial infection. Chlorhexidine is an advantageous antimicrobial because it has broad-spectrum coverage, is inexpensive, and is very well tolerated.
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Brooke, Emily, Simon Tappin, and Federico Corletto. "Comparison of canine intravenous catheter site preparation with standard chlorhexidine gluconate and isopropyl alcohol scrub versus a commercial single-use 2% chlorhexidine gluconate and 70% isopropyl alcohol applicator." In BSAVA Congress Proceedings 2017, 561. British Small Animal Veterinary Association, 2017. http://dx.doi.org/10.22233/9781910443439.74.22.

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Conference papers on the topic "Chlorhexidine gluconate"

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Boyan, WL, J. Ried, and T. Caton. "Skin Decontamination with Chlorhexidine Gluconate for the Control of Nosocomial Acinetobacter in a Long Term Acute Care Hospital." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1427.

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