Academic literature on the topic 'CHLORO DERIVATIVES'

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Journal articles on the topic "CHLORO DERIVATIVES"

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Drašar, Pavel, and Jiří Beránek. "2',3'-O-Carbonyl derivatives of 6-azauridine in the synthesis of its 5-substituted and 5'-deoxy derivatives." Collection of Czechoslovak Chemical Communications 52, no. 8 (1987): 2070–82. http://dx.doi.org/10.1135/cccc19872070.

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Preparation of 2',3'-O-carbonyl derivatives of 5'-deoxy-6-azauridine and 6-azauridine using 1,1'-carbonyldiimidazole has been elaborated. 5'-Chloro and 5'-bromo derivatives were prepared by treatment of the 5'-O-mesyl derivative with quaternary ammonium halides, 5'-chloro derivatives also by direct halogenation with thionyl chloride in hexamethylphosphortriamide or with tetrachloromethane, triphenyl phosphine, and dimethylformamide. Derivatives of 5'-bromo-6-azauridine were reduced with tributyltin hydride to 5'-deoxy-6-azauridine compounds. 6-Azauridine 2',3'-carbonate (IVa) and its 5'-deriva
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K. Abdullah, Ebtihal. "Synthesis of New (1-alkylamino-4-phenyldithio-2-bntanol amine) andderivatives." Tikrit Journal of Pharmaceutical Sciences 6, no. 1 (2023): 78–82. http://dx.doi.org/10.25130/tjphs.2010.6.1.12.78.82.

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Anew series of(1-alkylamino-4-phenyldithio-2-bntanol amine) and derivatives,containing two functional groups (pheny ring and NCS2) here been prepared from a reaction by 3steps :- 1-In the first step the preparation of n-phenyl dithio carbamate (A) and derivatives from a reaction between Aniline and carbon disulfide in basic medium. 2-Then , preparation N-3-chloro-2-hydroxy propyl amine tt 3 )) and derivativel from reaction between N-3-chloro-2-hydroxy propylamine and epichloro hydrine in methanolic a queous.3-In three step :-preparation 1-Alkyi amino -4-phenyl dithio-2-butanol amine ( I-IV) fr
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Knörzer, Gabriele, Hermann Seyffer, Hans Pritzkow, and Walter Siebert. "Neuartige Allylboran- und Allyldiboran(4)-Derivate / Novel Allylboran- and Allyldiboran(4) Derivatives." Zeitschrift für Naturforschung B 45, no. 7 (1990): 985–88. http://dx.doi.org/10.1515/znb-1990-0712.

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Allyldiboran(4) derivatives la—c are obtained from allylmagnesium chloride and chloro derivatives of diboran(4). la—c are air-sensitive liquids; heating of le did not yield a 2,3-dihydro-l,2-diborole derivative (B). Reaction between 1,1-bis(dichloroboryl)-3,3-dimethyl-butane (5) and H2C=C(CH2SnMe3)2 (4) leads to the heat-sensitive chloro derivative 2a, in which the chlorine is substituted by Me3SiNMe2 to give stable 1,3-bis-dimethylamino-5-methylene-2-neopentyl- 1,3-diborinane (2 b). 1,2-Bis(dichloroboryl)benzene and 4 yield the chloro derivative 3a, and its substitution with HN(i-Pr)2 leads t
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Neamah, Rawaa, та Shaimaa Adnan. "Study the Biological Activity for Shiff Base and Β – Lactam Compounds that Synthesis and Identification from Pyrimidine Derivatives". International Journal of Pharmaceutical Quality Assurance 11, № 01 (2013): 37–39. http://dx.doi.org/10.25258/ijpqa.11.1.12.

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In This study We are synthesis and characterization of some Schiff base and β- lactam derivatives) by three steps. The First react 2-amino-4-Chloro-6-methyl pyrimidine with 4-amino acetophenone in an acid medium to get shiff base derivative(E)-4-(1-((4-Chloro-6-methyl pyridine-2-yl)imino)ethyl)aniline (1), the second step (1) react with (3,4- dimethoxybenzal dehyde,4-methyl benzaldehyde,4-dimethylamino benzaldehyde,4-bromo benzaldehyde,4–hydroxy benzaldehyde, 4-Nitro benzaldehyde) to get Schiff base derivatives (2-7), the last step (2-7) derivatives react with Chloro acetyl chloride to get –β-
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Krečmerová, Marcela, Hubert Hřebabecký, and Antonín Holý. "Synthesis of 5-Phenylcytosine Nucleoside Derivatives." Collection of Czechoslovak Chemical Communications 61, no. 4 (1996): 645–55. http://dx.doi.org/10.1135/cccc19960645.

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Reaction of silylated 5-phenylcytosine with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribose, catalyzed with tin tetrachloride, and subsequent methanolysis afforded 5-phenylcytidine (2). This compound reacted with thionyl chloride in acetonitrile to give cyclic sulfite 3 which on heating in dimethylformamide was converted into 2,2'-anhydro-1-(β-D-arabinofuranosyl)-5-phenylcytosine (4). Analogous reaction of compound 2 with thionyl chloride at reflux gave 5'-chloro-5'-deoxy-2',3'-cyclic sulfite 5. Its heating in dimethylformamide afforded 5'-chloro-2,2'-anhydro derivative 6, mild alkaline hydrolysis led
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Dillip, Kumar Ojha, N. Prasad R., Rao Hitesh, Gupta Yogesh, Agrawal Umesh, and Chand Pooran. "Adenosine receptors. Part 1 : (2S,3S,4R,5R)-2-(4-(alkyl/arylamino)-5Hpyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)pyrrolidine-3,4-diol derivatives as possible adenosine receptor agonists." Journal of Indian Chemical Society Vol. 91, Aug 2014 (2014): 1451–57. https://doi.org/10.5281/zenodo.5728670.

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Department of Chemistry, University of Rajasthan, Jaipur-302 004, Rajasthan, India Therachem Research Medilab (Ind) Pvt. Ltd., E 969, Biotechnology Park, Sitapura Industrial Area, Jaipur-302 022, Rajasthan, India <em>E-mail</em> : ojha79@gmail.com, pchand@therachemlab.com, rnp_1949@yahoo.co.in <em>Manuscript received 19 January 2014, accepted 01 February 2014</em> 6-Substitued adenosine derivatives are well known adenosine receptor agonists and a few of these derivatives are being used as therapeutic agents. A series of novel N<sup>6</sup> -substituted-9-deaza adenosine or N<sup>4</sup> -subst
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Horáčková, Jaroslava, and Vojeslav Štěrba. "Coupling Kinetics of Benzenediazonium Ions with 2,6-Dioxo-3-(p-substituted phenylhydrazono)-1,2,3,6-tetrahydropyridine-4-carboxylic Acid." Collection of Czechoslovak Chemical Communications 57, no. 9 (1992): 1915–27. http://dx.doi.org/10.1135/cccc19921915.

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The kinetics have been measured of the reactions of 4-nitro-, 4-chloro-, and 4-methoxybenzenediazonium ions with substituted phenylazo derivatives of citrazinic acid in buffer solutions, and the pKa values of the corresponding monoazo and bisazo compounds have been estimated. The reactions of 4-nitrobenzenediazonium ion with 4-chloro- and 4-methoxyphenylazo derivatives and of 4-chlorobenzenediazonium ion with 4-methoxyphenylazo derivative were accompanied by a partial replacement of the substituted phenylazo group by the 4-nitro- and 4-chlorophenylazo groups, respectively. The reactions of 4-c
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More, Paresh S., and Santosh G. Singh. "Synthesis and Characterization of Ester Derivatives of Stilbene Derived from Acid Derivative (of P-Chloro Phenyl Acetic Acid, Substitute Benzaldehyde, Triethyl Amine) with Methanol and Sulphuric Acid." International Letters of Chemistry, Physics and Astronomy 47 (February 2015): 49–55. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.47.49.

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Two stilbene derivatives have been synthesized in two step process. First step involved synthesis of acid derivative from p-chloro phenyl acetic acid, substituted benzaldehyde and triethyl amine, where as the second step involved synthesis of substituted stilbene derivatives (enoate or esters) through very simple route. These derivatives were characterized by various spectral techniques and were screened for their antimicrobial activities.
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More, Paresh S., and Santosh G. Singh. "Synthesis and Characterization of Ester Derivatives of Stilbene Derived from Acid Derivative (of P-Chloro Phenyl Acetic Acid, Substitute Benzaldehyde, Triethyl Amine) with Methanol and Sulphuric Acid." International Letters of Chemistry, Physics and Astronomy 47 (February 24, 2015): 49–55. http://dx.doi.org/10.56431/p-7bsx45.

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Two stilbene derivatives have been synthesized in two step process. First step involved synthesis of acid derivative from p-chloro phenyl acetic acid, substituted benzaldehyde and triethyl amine, where as the second step involved synthesis of substituted stilbene derivatives (enoate or esters) through very simple route. These derivatives were characterized by various spectral techniques and were screened for their antimicrobial activities.
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Rádl, Stanislav, and Lenka Kovářová. "Some reactions of N-propadienyl-4-quinolones." Collection of Czechoslovak Chemical Communications 56, no. 11 (1991): 2413–19. http://dx.doi.org/10.1135/cccc19912413.

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N-Alkylation of ethyl 6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate (Vg) with 3-bromopropyne followed by acidic hydrolysis provided N-propyl derivative Ic which in alkaline media yielded N-propadienyl derivative IId. Propadienyl derivatives IIa and IIb treated with primary or secondary amines provided intermediates IIIa-IIIc which were hydrolyzed to N-acetonyl derivatives IVa and IVb, respectively. N-Benzylation of ethyl 7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate (Va) followed by hydrolysis yielded 1-benzyl-7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic ac
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Dissertations / Theses on the topic "CHLORO DERIVATIVES"

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Shtamburg, V. G., A. V. Tsyhankov, V. V. Shtamburg, et al. "1-(N-Alkoxyamino)pyridine Derivatives and others N-Alkoxyhydrazines." Thesis, Ekskluziv Publ, 2015. http://repository.kpi.kharkov.ua/handle/KhPI-Press/36899.

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Kitagawa, Kristen. "Studies in the asymmetric reduction of (3s)-3-amino-1-chloro-4-phenyl-2-butanone derivatives." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/39464.

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This thesis focuses on the asymmetric reduction of N-protected derivatives of (3S)-3-amino-1-chloro-4-phenyl-2-butanone to their corresponding diastereomeric alcohol products, which are key intermediates in the synthesis of HIV protease inhibitors. Although the stereoselective synthesis of the (S,S) alcohol product is easily achieved, preparing the (R,S) diastereomer is much more challenging. I investigated three diastereoselective reduction processes: 1) Meerwein-Ponndorf-Verley (MPV) reduction, 2) asymmetric transfer hydrogenation, and 3) boron reducing agents. The diastereoselectivity of
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Sharma, Prawin Kumar. "Greener approach to the synthesis of some novel class of isoxazolidine and isoxazoline derivatives using N-methyl and N-phenyl-a-chloro nitrones." Thesis, University of North Bengal, 2016. http://ir.nbu.ac.in/handle/123456789/1884.

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Yon-Hin, Paul. "Syntheses of chlorin, benzoporphyrin and bacteriochlorin derivatives." Thesis, University of British Columbia, 1989. http://hdl.handle.net/2429/29324.

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The syntheses of chlorin, benzoporphyrin, and bacteriochlorin derivatives are presented in this thesis. The key step in each synthesis involved a Diels-Alder reaction of a vinylporphyrin with an appropriate dienophile. The vinylporphyrins 81,101 and 106 were prepared in high yield using a variation of Johnson's regioselective synthesis employing dipyrromethenes 93,94,104, and 144 as crucial building blocks. As the first objective, the Diels-Alder reactions of 81 with 1,2-disubstituted vinyl sulfones were investigated in order to provide a route to chlorin derivatives which could act as interm
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Helaja, Juho. "Structural analysis of natural chlorin derivatives utilizing NMR spectroscopy and molecular modelling." Helsinki : University of Helsinki, 2000. http://ethesis.helsinki.fi/julkaisut/mat/kemia/vk/helajaj/.

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Assafi, Mohamed. "Etude comparée en vaporeformage des aromatiques substitués sur catalyseurs métalliques." Poitiers, 1987. http://www.theses.fr/1987POIT2298.

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Influence des groupements fonctionnels (oh, cl, no::(2)) sur les reactivites des liaisons c-c de composes aromatiques, en presence d'eau ou d'hydrogene sur les catalyseurs rh/al::(2)o::(3), ni/al::(2)o::(3) et pol/al::(2)o::(3)
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Cao, Yanyan. "Anti-diabetic and Anti-cancer Activities of Penta-O-galloyl-alpha-D-glucopyranose (alpha-PGG) and Its Derivative 6-chloro-6-deoxy-1,2,3,4-tetra-O-galloyl-alpha-D-glucopyranose (6Cl-TGQ)." Ohio University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1257458049.

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Cao, Yanyan. "Anti-diabetic and anti-cancer activities of penta-O-galloyl-alpha-D-glucopyranose (alpha-PGG) and its derivative 6-chloro-6-deoxy-1,2,3,4-tetra-O-galloyl-alpha-D-glucopyranose (6CI-TGO)." Ohio : Ohio University, 2009. http://www.ohiolink.edu/etd/view.cgi?ohiou1257458049.

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Grignon, Claire. "Toxicocinétique en santé environnementale : application à la mesure de l'exposition aux perturbateurs endocriniens." Thesis, Poitiers, 2016. http://www.theses.fr/2016POIT1405/document.

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Le bisphénol A (BPA), ubiquitaire dans l'environnement, est reconnu comme étant un perturbateur endocrinien (PE). La forte réactivité du BPA avec le chlore entraine la formation de dérivés chlorés du BPA (ClxBPA), possédant une activité perturbatrice endocrinienne supérieure au BPA. En santé environnementale, l'évaluation du risque chez l'homme implique notamment la mise en place d'études de biomonitoring et de toxicocinétique nécessitant l'analyse des micropolluants environnementaux dans les milieux biologiques.Afin d'estimer l'exposition des populations au BPA et ClxBPA, une méthode d'analys
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Bacle, Astrid. "Perturbateurs endocriniens et patients en insuffisance rénale chronique terminale : impact des techniques d'hémodialyse sur l'exposition au Bisphénol A et à ses dérivés chlorés." Thesis, Poitiers, 2017. http://www.theses.fr/2017POIT1406/document.

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Les conditions de sécurité sanitaire encadrant les pratiques d'hémodialyse (HD) et d'hémodiafiltration (HDF) n'intègrent pas les risques liés à des micropolluants comme les perturbateurs endocriniens (PE). Les patients dialysés présentent un risque de surexposition au Bisphénol A (BPA), reconnu comme PE, en raison de sa présence dans les dispositifs médicaux utilisés lors de la dialyse et du risque d'accumulation liée à leur état rénal.Nos premiers travaux ont confirmé la présence du BPA dans les dialyseurs et démontré pour la 1ère fois que l'eau utilisée en HD était également une source de co
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Book chapters on the topic "CHLORO DERIVATIVES"

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Grikina, O. E., L. S. Khaikin, and M. Alcolea Palafox. "Joint Use of AB Initio Calculations, Vibrational Spectroscopy, Electron Diffraction, and Microwave Data in the Investigation of the Structure and Intramolecular Dynamics of 1, 3, 2-Dioxaphospholene and its 2-Chloro- and 2-Chloro-4, 5-Dimethyl- Derivatives." In Spectroscopy of Biological Molecules: Modern Trends. Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-011-5622-6_244.

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Lacherai, A., R. De Jaeger, A. Mazzah, C. Fournier, and B. Hecquet. "Spectroscopic Study of N,N,-bis(chloro-2 Ethyl)Amino Derivatives of HN(P(O)Cl2)2. Application to the Synthesis of Compounds Exhibiting Antitumoral Activity." In Spectroscopy of Biological Molecules. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0371-8_242.

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Cubeddu, R., W. F. Keir, R. Ramponi, and T. G. Truscott. "Photophysical Properties of Chlorin Derivatives of Haematoporphyrin." In Photosensitisation. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73151-8_50.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) chloro complex with tripodal peralkylguanidine derivative." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 7. Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-65895-6_409.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) chloro complex with an azo derivative." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 4. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62474-6_487.

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Steen-Ecke, Stefanie, Franz-Peter Montforts, and Detlef Gabel. "Subcellular Localization of BSH-Containing and Non-Boron- Containing Chlorin Derivatives in Living Cells Using Confocal Laser Scanning Microscopy." In Frontiers in Neutron Capture Therapy. Springer US, 2001. http://dx.doi.org/10.1007/978-1-4615-1285-1_132.

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Tidwell, T. T. "Chloro- and Dichloroketenes." In Three Carbon-Heteroatom Bonds: Thio-, Seleno-, and Tellurocarboxylic Acids and Derivatives; Imidic Acids and Derivatives; Ortho Acid Derivatives. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-023-00095.

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Cordero, F. M., and S. Cicchi. "-Chloro-Substituted Nitrones." In Three Carbon-Heteroatom Bonds: Amides and Derivatives; Peptides; Lactams. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-022-00360.

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Zimmer, R. "Of Chloro-Substituted Butatrienes." In Three Carbon-Heteroatom Bonds: Ketenes and Derivatives. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-024-00085.

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Tidwell, T. T. "Chloro(cyano)ketene by Thermolysis of 4-Azido-3-chloro-5-methoxyfuran-2(5)-one." In Three Carbon-Heteroatom Bonds: Thio-, Seleno-, and Tellurocarboxylic Acids and Derivatives; Imidic Acids and Derivatives; Ortho Acid Derivatives. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-023-00104.

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Conference papers on the topic "CHLORO DERIVATIVES"

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Bernede, J. C., M. Jamali, T. B. Nasrallah, and A. Conan. "Photosensitive properties of silver chloro anturaquinone derivatives." In International Conference on Science and Technology of Synthetic Metals. IEEE, 1994. http://dx.doi.org/10.1109/stsm.1994.835476.

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Bittner, Shmuel, and Thida Win. "Direct Nitration of 3-Arylamino-2-Chloro-1,4-Naphthoquinones; Novel Quinone Derivatives." In The 9th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2005. http://dx.doi.org/10.3390/ecsoc-9-01473.

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Techasakul, Supanna, Nisachon Khunnawutmanothum, Nitirat Chimnoi, Pornpan Pungpo, Suda Louisirirotchanakul, and Supa Hannongbua. "Novel 2-Chloro-8-arylthiomethyldipyridodiazepinone Derivatives with Activity against HIV-1 Reverse Transcriptase." In The 10th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2006. http://dx.doi.org/10.3390/ecsoc-10-01422.

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Bułakowska, Anita, Jarosław Sławiński, and Rafał Hałasa. "Evaluation of the Antimicrobial Activity of N-Acylated 4-Chloro-2-mercaptobenzenesulfonamide Derivatives." In ECMC 2022. MDPI, 2022. http://dx.doi.org/10.3390/ecmc2022-13289.

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Kepeňová, Martina, Michaela Benediková, Mária Vilková, Miroslava Litecká, and Ivan Potočňák. "Ionic palladium(II) complexes with nitro and halogen derivatives of 8-hydroxyquinoline." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.443k.

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Four commercially unavailable derivatives of 8-hydroxyquinoline with different functional groups (nitro and halogen) in positions 5 and 7 were prepared: 5-nitro-7-iodo-8-hydroxyquinoline (HNIQ), 5-nitro-7-bromo-8-hydroxyquinoline (HNBrQ), 5-iodo-7-bromo-8-hydroxyquinoline (HIBrQ) and 5-chloro-7-bromo-8-hydroxyquinoline (HClBrQ). Their characterization was performed by IR and NMR spectroscopy, elemental analysis and in the case of HIBrQ and HClBrQ by single crystal X-ray structure analysis. Prepared compounds were used for the synthesis of new palladium(II) complexes NH2(CH3)2[PdCl2(XQ)], where
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Simijonović, Dušica, Marko Antonijević, Edina Avdović, Zorica Petrović, and Zoran Marković. "INHIBITORY EFFECT OF COUMARIN BENZOYLHYDRAZONES ON MCL-1 PROTEIN." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.442s.

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The protein that controls cell differentiation in acute myeloid leukemia is MCL-1. High-level of this protein causes the carcinogenesis. In this paper inhibitory effect of two coumarin benzoylhydrazones,(E)-2-hydroxy-N’-(1-(2-oxo-2H-chromen-3-yl)ethylidene)benzohydrazide (A) and (E)-4-hydroxy-N’-(1-(2-oxo-2H-chromen-3-yl)ethylidene)benzohydrazide (B) against MCL-1 protein was investigated. For this purpose, a molecular docking simulations were used. The obtained results showed that compound A showed better activity than compound B. Also, the docking simulations against MCL-1 protein were perfo
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El Rayes, Samir, Ahmed Aboelmagd, Mohamed Gomaa, Ibrahim Ali, and Walid Fathalla. "Convenient synthesis of some new 3-(4-chloro-phenyl)-3-hydroxy-2,2-dimethyl-propionic acid methyl ester derivatives of expected Anticancer Activity." In The 23rd International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2019. http://dx.doi.org/10.3390/ecsoc-23-06492.

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Zorin, Vladimir P. "Intra- and intermembrane distribution of chlorin e6 derivatives." In Photodynamic Therapy of Cancer II. SPIE, 1995. http://dx.doi.org/10.1117/12.199171.

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Colasanti, Alberto, Annamaria Kisslinger, Dirk Kusch, et al. "Comparison of the photoactivation efficacy of two chlorin derivatives." In BiOS Europe '96, edited by Stanley B. Brown, Benjamin Ehrenberg, and Johan Moan. SPIE, 1996. http://dx.doi.org/10.1117/12.260792.

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Charankevich, S. N., Vladimir P. Zorin, Tatyana E. Zorina, Ivan I. Khludeyev, and Iosif S. Mikhalovsky. "Regulation of photosensitizing activity of chlorin e6 derivatives in biosystems." In Laser Applications in Life Sciences: 5th International Conference, edited by Pavel A. Apanasevich, Nikolai I. Koroteev, Sergei G. Kruglik, and Victor N. Zadkov. SPIE, 1994. http://dx.doi.org/10.1117/12.197443.

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