Academic literature on the topic 'Chloro Position'

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Journal articles on the topic "Chloro Position"

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A., RAMESH, SYAMA SUNDAR B., and S. RADHAKRISHNA MURTI P. "Kinetics of Substitution of 2,4,6-Trichlorofyrimidine Enhanced Reactivity of 2-Chloro Position." Journal of Indian Chemical Society Vol. 72, Jun 1995 (1995): 413–15. https://doi.org/10.5281/zenodo.5905003.

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Department of Chemistry, Nagarjuna University, Nagarjunanagar-522 510 <em>Manuscript received 24 August 1993, accepted 14 December 1993</em> Kinetics of Substitution of 2,4,6-Trichlorofyrimidine Enhanced Reactivity of 2-Chloro Position
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Rajam, Ammaiyappan, Packianathan Thomas Muthiah, Raymond John Butcher, Jerry P. Jasinski, and Jan Wikaira. "Design of two series of 1:1 cocrystals involving 4-amino-5-chloro-2,6-dimethylpyrimidine and carboxylic acids." Acta Crystallographica Section C Structural Chemistry 74, no. 9 (2018): 1007–19. http://dx.doi.org/10.1107/s2053229618009154.

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Two series of a total of ten cocrystals involving 4-amino-5-chloro-2,6-dimethylpyrimidine with various carboxylic acids have been prepared and characterized by single-crystal X-ray diffraction. The pyrimidine unit used for the cocrystals offers two ring N atoms (positions N1 and N3) as proton-accepting sites. Depending upon the site of protonation, two types of cations are possible [Rajam et al. (2017). Acta Cryst. C73, 862–868]. In a parallel arrangement, two series of cocrystals are possible depending upon the hydrogen bonding of the carboxyl group with position N1 or N3. In one series of co
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Hayashi, Norihiro, Yoshihiro Nakata, and Akira Yazaki. "New Findings on the Structure-Phototoxicity Relationship and Photostability of Fluoroquinolones with Various Substituents at Position 1." Antimicrobial Agents and Chemotherapy 48, no. 3 (2004): 799–803. http://dx.doi.org/10.1128/aac.48.3.799-803.2004.

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ABSTRACT The present study examined the phototoxicities of a series of 7-(3-aminopyrrolidinyl) quinolones containing various substituents at position 1 (in which the substituent at R8 is a hydrogen or a halogen) by use of a mouse model. For the 7-(3-aminopyrrolidinyl) quinolones with a halogen atom at position 8, well-known substituent groups such as a cyclopropyl, an ethyl, or a difluorophenyl at position 1 were found to be responsible for severe phototoxicity. However, when an aminodifluorophenyl or an isoxazolyl group was placed at position 1, even 8-halogeno quinolones were found to be mil
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Cherubim, P., and LW Deady. "Nucleophilic Substitution Reactions in Benzo[C][1,8]naphthyridines. II." Australian Journal of Chemistry 43, no. 8 (1990): 1469. http://dx.doi.org/10.1071/ch9901469.

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3-Chloro-1-methyl-6-(p- methylphenoxy ) benzo [c][1,8] naphthyridine has been prepared, the reactions with various nitrogen, oxygen and sulfur nucleophiles studied, and the results compared with those for the 1- chloro-3-methyl isomer. The 6-position was more reactive for oxygen and nitrogen nucleophiles, so much so that an initially added 6-NHR group was displaced by a second R′NH2 nucleophile at least as readily as was the 3-chloro group. With p- chloro ( thiophenol ), however, the 3-chloro group was preferentially displaced.
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Deady, LW, and DM Werden. "Nucleophilic-Substitution Reactions in Benzo[C][1,8]Naphthyridines." Australian Journal of Chemistry 39, no. 4 (1986): 667. http://dx.doi.org/10.1071/ch9860667.

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The reactions of 1-chloro-3-methyl-6-(p- methylphenoxy ) benzo [c][1,8] naphthyridine with a variety of nucleophiles are reported. The relative reactivity of the 1- and 6-positions depends on the nucleophile and reaction conditions. Anilines, and alkyl and aryl thioxides react at position 1, alkylamines and alkoxide at position 6, and acidified alcohol at both 1 and 6. Some possible reasons for these positional reactivities are discussed.
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Birzan, Liviu, Mihaela Cristea, Constantin Draghici, Victorita Tecuceanu, Maria Maganu, and Alexandru C. Razus. "4-(azulen-1-yl)-2,6-diphenylchalcogenopyrylium Perchlorates; Synthesis and Characterization." Revista de Chimie 71, no. 6 (2020): 89–95. http://dx.doi.org/10.37358/rc.20.6.8174.

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2,6-Diphenyl substituted thio- and seleno-pyrylium salts with azulen-1-yl moieties in 4-position were prepared from phenylacetylene going through chalcogenopyrones and 4-chloro-chalcogenopyrylium salts as intermediates. The final step of synthesis involves the electrophile substitution in 1-position of azulenes with the obtained chloro-derivatives and the products isolation as stable perchlorates. The electronic and magnetic spectra of products are presented and compared with those of the corresponding pyrylium salts.
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Bzowska, A., Z. Kazimierczuk, and F. Seela. "7-Deazapurine 2'-deoxyribofuranosides are noncleavable competitive inhibitors of Escherichia coli purine nucleoside phosphorylase (PNP)." Acta Biochimica Polonica 45, no. 3 (1998): 755–68. http://dx.doi.org/10.18388/abp.1998_4269.

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A series of 7-deazapurine 2'-deoxyribofuranosides were synthesized according to already known procedures and their substrate and inhibitor properties with purified E. coli purine nucleoside phosphorylase were examined. In agreement with previous findings, substrate activity was not detected for any of the compounds tested. Most of the nucleosides showed weak inhibition in the preliminary screening, i.e. at a concentration of about 100 microM. However some combinations of 6-chloro, 6-amino or 6-methoxy substituents with bulky hydrophobic groups at position 7 of the base and/or chloro, amino, me
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Hfaiedh, Anoir, Hamed Ben Ammar, Jean-François Soulé, and Henri Doucet. "Palladium-catalyzed regioselective C–H bond arylations at the C3 position of ortho-substituted fluorobenzenes." Organic & Biomolecular Chemistry 15, no. 35 (2017): 7447–55. http://dx.doi.org/10.1039/c7ob01689a.

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We report herein the palladium-catalyzed C–H bond arylation of fluorobenzene derivatives at the ortho-position to the fluorine atom. Bromo, chloro or methoxy substituents at the fluorobenzenyl ortho-position can be used to increase the reactivity of the C–H bond at the C3 position.
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Matsunami, Asuka, Shigeki Kuwata, and Yoshihito Kayaki. "Regioselective Transfer Hydrogenative Defluorination of Polyfluoroarenes Catalyzed by Bifunctional Azairidacycle." Organics 3, no. 3 (2022): 150–60. http://dx.doi.org/10.3390/org3030012.

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The catalytic hydrodefluorination (HDF) with a bifunctional azairidacycle using HCOOK was examined for cyano- and chloro-substituted fluoroarenes, including penta- and tetrafluorobenzonitriles, tetrafluoroterephthalonitrile, tetrafluorophthalonitrile, 3-chloro-2,4,5,6-tetrafluoropyridine, and 4-cyano-2,3,5,6-tetrafluoropyridine. The reaction was performed in the presence of a controlled amount of HCOOK with a substrate/catalyst ratio (S/C) of 100 in a 1:1 mixture of 1,2-dimethoxyethane (DME) and H2O at an ambient temperature of 30 °C to obtain partially fluorinated compounds with satisfactory
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Pham, Em Canh, Tuong Vi Thi Le, and Tuyen Ngoc Truong. "Design, synthesis, bio-evaluation, and in silico studies of some N-substituted 6-(chloro/nitro)-1H-benzimidazole derivatives as antimicrobial and anticancer agents." RSC Advances 12, no. 33 (2022): 21621–46. http://dx.doi.org/10.1039/d2ra03491c.

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The purpose of this study is to synthesize novel N-substituted 6-(chloro/nitro)-1H-benzimidazole derivatives with various substituted aryl groups at position 2 and alkylation at position 1, and evaluate their antimicrobial and anticancer activities.
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Dissertations / Theses on the topic "Chloro Position"

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Gauduchon, Emmanuelle. "Fonctionnalisation régiosélective en position 4 ou 5 ducycle 1,2,3-thiadiazole et applications." Poitiers, 1998. http://www.theses.fr/1998POIT2333.

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Dans la premiere partie de ce travail, nous avons rationalise la preparation de matieres premieres 1,2,3-thiadiazoliques monofonctionnalisees en position 4 ou 5. Nous avons ainsi obtenu des esters, acides, derives d'acide et amines qui nous ont permis de realiser la synthese deux series d'amides n-substitues (n-arylthiadiazolylcarboxamides et n-thiadiazolylbenzamides) et une serie d'aldimines conjuguees (n-thiadiazolylbenzaldimines). Dans la seconde partie, nous avons prepare trois carbures 1,2,3-thiadiazoliques et transforme les amines primaires 1,2,3-thiadiazoliques en derives halogenes. Nou
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Books on the topic "Chloro Position"

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Armstrong, Joshua. Maps and Territories. Liverpool University Press, 2019. http://dx.doi.org/10.3828/liverpool/9781786942012.001.0001.

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The rapidity of postwar globalization and the structural changes it has brought to both social and spatial aspects of everyday life have meant, in France as elsewhere, the destabilizing of senses of place, identity, and belonging, as once familiar, local environments are increasingly de-localized and made porous to global trends and planetary preoccupations. Maps and Territories identifies such preoccupations as a fundamental underlying impetus for the contemporary French novel. Indeed, like France itself, the protagonists of its best fiction are constantly called upon to renegotiate their ide
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Book chapters on the topic "Chloro Position"

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"Rational design, synthesis and biological evaluation of dual- binding reversible inhibitors of cholinesterase’s with mild inhibitory potency toward monoamine oxidase B." In Book of Abstracts - RAD 2025 Conference. RAD Centre, Niš, Serbia, 2025. https://doi.org/10.21175/rad.abstr.book.2025.21.3.

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Alzheimer’s disease (AD) is neurodegenerative disease that is the cause of 60-70% of dementia cases. The major symptoms of AD involve progressive decline of cognitive and motor skills, caused by neuropathological changes, including elevation of oxidative stress, shrinkage of neurons, formation of Aβ plaques and neurofibrillary tangles in the central nervous system (CNS) and disruption of glutamatergic and cholinergic neurotransmission systems. In AD, the nerve terminal disruption is observed in immediate vicinity of Aβ plaques. Peripheral ionic site of AChE promotes aggregation of Aβ peptides
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Herrmann, Reinhold g. "Photosynthesis research: aspects and perspectives." In Molecular Genetics of Photosynthesis. Oxford University PressOxford, 1996. http://dx.doi.org/10.1093/oso/9780199634484.003.0001.

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Abstract Biological photosynthesis, that is, the conversion of solar energy into high-energy chemical metabolites (ATP, NADPH, and carbohydrates), is globally the most fundamental biochemical process. It provides energy, organic matter, and oxygen for nearly all biotic processes, and it is the only renewable energy source of our planet. Life in its present form depends on it. The conversion of solar to chemical energy, which in oxygenic photosynthesis is accompanied by the evolution of molecular oxygen, is catalysed by thylakoid membranes that are found in prokaryotic cells and in the photosyn
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A. Elrashedy, Ahmed. "Targeting Inhibitor of Enterococcus faecalis: Insights from Comparative Molecular Dynamics and Binding Free Energy Analyses." In Infectious Diseases. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.114329.

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For the past 50 years, antibiotics that target DNA gyrase have proven to be clinically successful. As a result, the search for novel gyrase inhibitors has intensified due to the rise in bacterial resistance. Since it is absent in eukaryotes yet essential in all bacteria, anti-bacterials target it aggressively. Although quinolones are a clinically approved medication, both Gram-positive and Gram-negative bacteria are developing resistance to them, which compromises their therapeutic efficacy. Thus, it is vital to identify novel compounds that can efficiently inhibit DNA gyrase. A recent experim
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RENAUDEAU, Claude. "Les préparatifs industriels et tactiques allemands." In Médecine et Armées Vol. 45 No.1. Editions des archives contemporaines, 2017. http://dx.doi.org/10.17184/eac.7448.

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L’Empire allemand proclamé par le chancelier Bismarck le 18 janvier 1871 et placé sous l’autorité du roi de Prusse a connu un essor démographique ainsi qu’une prospérité économique, militaire, scientifique et technique. De ce fait, il devint sous Guillaume II, dans les années 1910, la première puissance économique et militaire européenne, dotée de grandes industries comme KRUPP, SIEMENS ainsi qu’AGFA, BAYER et BASF pour la chimie. Au plan tactique, l’objectif de l’Allemagne est de disposer d’une armée suffisamment puissante capable de vaincre rapidement la France avant de s’attaquer ensuite à
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Gott, Michael. "Drawing Outside the Lines." In Quebec Cinema in the 21st Century. Liverpool University Press, 2024. http://dx.doi.org/10.3828/liverpool/9781802074765.003.0002.

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This chapter focuses on the porous and shifting borders of contemporary Quebec filmmaking through the example of six recent films, several of which are directed by women, immigrant, and Indigenous filmmakers, and many of which feature a diverse cast of characters who speak a number of languages besides French. These are Uvanga (Marie-Hélène Cousineau and Madeline Ivalu, 2014), Une colonie (A Colony, Geneviève Dulude-De Celles, 2019), Montréal la blanche (Bachir Bensaddek, 2016), Le meilleur pays du monde (The Greatest Country in the World, Ky Nam Le Duc, 2020), Pays (Boundaries, Chloé Robichau
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Barrera-Violeth, Jose Luis, Ana Melisa Jiménez-Ramirez, and Ana Milena Vásquez-Bettin. "Desert species: seed germination, ecological achievement, and land area protection." In PLANTS: Physiology, crop production, and stress responses. Editora Científica Digital, 2025. https://doi.org/10.37885/250419149.

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This study investigates the effects of seasonal variations on seed germination, dormancy, and ecological strategies in desert-adapted grasses and halophytes. Using species such as Chloria virgata, Coelachyrum brevifolium, Cenchrus ciliaris, Pennisetum divisum, Panicum turgidum, Seidlitzia rosmarinus, and Halothamnus iraqensis, the research evaluates germination parameters under varying temperature regimes, light conditions, and seed bank types. Results revealed that seeds matured in summer exhibited higher mass, synchrony, and germination rates than winter-matured seeds, which displayed greate
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Pompelli, Marcelo F., Alfredo Jarma-Orozco, Juán de Diós Jaraba-Navas, Luis Alfonso Rodríguéz-Páez, and Yirlis Yadeth Pineda-Rodríguez. "Desert species: seed germination, ecological achievement, and land area protection." In Plant Science and Biotechnology: Some insight for a better choice for improvement of crop production and conservation. Editora Científica Digital, 2025. https://doi.org/10.37885/250218811.

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This study investigates the effects of seasonal variations on seed germination, dormancy, and ecological strategies in desert-adapted grasses and halophytes. Using species such as Chloria virgata, Coelachyrum brevifolium, Cenchrus ciliaris, Pennisetum divisum, Panicum turgidum, Seidlitzia rosmarinus, and Halothamnus iraqensis, the research evaluates germination parameters under varying temperature regimes, light conditions, and seed bank types. Results revealed that seeds matured in summer exhibited higher mass, synchrony, and germination rates than winter-matured seeds, which displayed greate
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Jolowicz, Daniel. "Longus and Vergil." In Latin Poetry in the Ancient Greek Novels. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780192894823.003.0008.

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Chapter 7 claims that Longus’ Daphnis and Chloe exhibits a sustained engagement with Vergil’s Eclogues and Aeneid, and, to a lesser extent, the Georgics. The introduction (Section 7.1) gathers the evidence for the novel as the composition of a Romanized member of the Mytilenean Greek elite, descended from Pompey’s freedman, Theophanes of Mytilene, and suggests that it was written at some point during the second half of the second century; this will become particularly relevant to Section 7.8 on Longus’ subversive engagement with the Aeneid (a poem celebrating the Julian—not Pompeian!—claim to
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Conference papers on the topic "Chloro Position"

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Sucman, Natalia. "Diastereoselective synthesis of a novel cyclic derivative based on 2,3-indolinedione." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab18.

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Generally, organic synthesis is renowned for its predictability in determining results. Nevertheless, there are situations where instead of the expected products, unexpected compounds with unique structures may arise. This report is a presentation of one such remarkable cyclic compound with four chiral centres prepared by diastereoselective dimerization of Morita-Baylis-Hillman (MBH) adducts of acrylonitrile to 5-chloro-indole-2,3dione. MBH adducts are very popular in organic chemistry. They are synthesized by the addition of an activated alkene and a carbon electrophile in the presence of a n
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Ochiai, Shunsuke, Tomohiro Takayama, Yukiko Kishimura та ін. "Exposure characteristics of positive tone electron beam resist containing p-chloro-α-methylstyrene". У Photomask Japan 2017, редактор Kiwamu Takehisa. SPIE, 2017. http://dx.doi.org/10.1117/12.2279079.

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Tamaru, Kenta, Shunsuke Ochiai, Yukiko Kishimura, Hironori Asada, Ryoichi Hoshino та Minako Iwakuma. "Exposure characteristics of ternary copolymerization positive tone electron beam resist containing p-chloro-α-methylstyrene". У Photomask Japan 2018, редактор Kiwamu Takehisa. SPIE, 2018. http://dx.doi.org/10.1117/12.2324709.

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Kepeňová, Martina, Michaela Benediková, Mária Vilková, Miroslava Litecká, and Ivan Potočňák. "Ionic palladium(II) complexes with nitro and halogen derivatives of 8-hydroxyquinoline." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.443k.

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Four commercially unavailable derivatives of 8-hydroxyquinoline with different functional groups (nitro and halogen) in positions 5 and 7 were prepared: 5-nitro-7-iodo-8-hydroxyquinoline (HNIQ), 5-nitro-7-bromo-8-hydroxyquinoline (HNBrQ), 5-iodo-7-bromo-8-hydroxyquinoline (HIBrQ) and 5-chloro-7-bromo-8-hydroxyquinoline (HClBrQ). Their characterization was performed by IR and NMR spectroscopy, elemental analysis and in the case of HIBrQ and HClBrQ by single crystal X-ray structure analysis. Prepared compounds were used for the synthesis of new palladium(II) complexes NH2(CH3)2[PdCl2(XQ)], where
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Wang, Siqi, Colin P. McCoy, Gavin P. Andrews, Matthew Wylie, and Yi Ge. "Developing Functional Carbon-Dots Based Nanomaterials for Bacterial Inhibition." In 5th World Conference on Chemistry and Chemical Engineering and 5th World Conference on Advanced Materials, Nanoscience and Nanotechnology. Eurasia Conferences, 2024. https://doi.org/10.62422/978-81-970328-7-5-007.

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Carbon dots (CDs) are emerging nanomaterials, attracting increasing attention due to their exceptional properties, such as good biocompatibility, environmental friendliness, versatile functionalization capabilities, and cost-effectiveness. These attributes position CDs and CD-based nanomaterials as promising candidates for various biomedical applications. This study focuses on the development of functional CD-based nanomaterials conjugated with a photosensitizer Chlorin E6 to enhance bacterial inhibition. By employing a novel microwave-assisted approach, we successfully fabricated N-doped CDs
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