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Relevant bibliographies by topics / Chloroacetyl derivatives

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Academic literature on the topic 'Chloroacetyl derivatives'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Chloroacetyl derivatives"

1

Sokhraneva, V. A., D. A. Yusupova, V. S. Boriskin, and N. V. Groza. "Obtaining substituted phenol derivatives with potential antimicrobial activity." Fine Chemical Technologies 17, no. 3 (2022): 210–30. http://dx.doi.org/10.32362/2410-6593-2022-17-3-210-230.

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Objectives. With the growing resistance of pathogenic microorganisms to antibiotics, the development of new antimicrobial drugs offering specific mechanisms of action becomes an urgent task. Only few antimicrobials offer a broad spectrum of activity against gram-positive and gram-negative bacteria, molds, and yeasts. In this regard, the purpose of the work was to develop methods for synthesizing biologically active derivatives of alkyl-substituted phenols (reactions at the hydroxy group) to study their biological effect.Methods. The synthesis of imidazole acetates of substituted phenols was ca

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2

(Miss), A. M. DAVE, N. BHATT K., K. UNDAVIA N., and B. TRIVEDl P. "Studies on Synthesis of Haloginated Phenothiazine Derivatives." Journal of Chemical Indian Society Vol. 65, May 1988 (1988): 365–66. https://doi.org/10.5281/zenodo.6279483.

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University Department of Chemistry, Bhavnagar University Bhavnagar-.364-002 <em>Manuscript received 12 October 1987, revised 4 February 1988, accepted 21 March 1988</em> 1,3,7,9-Tetrachloro-10-(substituted-benzthiazol-2<em>'</em>-ylaminoacetyl)phenothiazines have been synthesised by condensation of the chloroacetyl derivative of phenothiazine with substituted-2-aminobenzthiazoles. The haloginated derivatives of phenothiazine were screened for their antibacterial efficacy.

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3

Tolba, Mahmoud S., Mostafa Sayed, Shaban A. A. Abdel-Raheem, Taher A. Gaber, Adel M. Kamal El-Dean, and Mostafa Ahmed. "Synthesis and spectral characterization of some new thiazolopyrimidine derivatives." Current Chemistry Letters 10, no. 4 (2021): 471–78. http://dx.doi.org/10.5267/j.ccl.2021.4.004.

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Thiazolopyrimidnes are considered one of the most interesting classes in heterocyclic chemistry due to their pharmaceutical importance. Herein, we report the synthesis of some new heterocyclic compounds containing thiazolopyrimidine starting from compound (1) which was previously prepared in literature. The starting compound was allowed to react with different alkylating agents such as chloroacetone, chloroacetyl chloride, and phenacyl bromide to afford derivatives (2-4). Compound (5), benzylidene derivative, was obtained by the reaction of compound (2) with benzaldehyde while amino-dicarbonit

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4

Flefel, Eman M., Walaa I. El-Sofany, Mahmoud El-Shahat, Arshi Naqvi, and Eman Assirey. "Synthesis, Molecular Docking and in Vitro Screening of Some Newly Synthesized Triazolopyridine, Pyridotriazine and Pyridine–Pyrazole Hybrid Derivatives." Molecules 23, no. 10 (2018): 2548. http://dx.doi.org/10.3390/molecules23102548.

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A series of novel pyridine and fused pyridine derivatives have been prepared starting from 6-(3,4-dimethylphenyl)-2-hydrazinyl-4-(thiophen-2-yl)-pyridine-3-carbonitrile 1 which on treatment with appropriate formic acid, acetic acid/ acetic anhydride, benzoyl chloride and/or carbon disulfide afforded the corresponding triazolopyridine derivatives 2–5. Also, treatment of hydrazide 1 with diethyloxalate, chloroacetyl chloride, chloroacetic acid and/or 1,2-dichloroethane yielded the corresponding pyridotriazine derivatives 7–10. Further transformation of compound 1 with a different active methylen

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5

KRISHNA, C. JOSHI, N. PATHAK VIJAI, and K. GOYAL MAHENDRA. "Synthesis, Anticonvulsant and Analgesic Activities of some New Fluorine containing 1,3,5-Trisubstituted-hydantoins." Journal of Indian Chemical Society Vol. 62, Nov 1985 (1985): 904–8. https://doi.org/10.5281/zenodo.6325270.

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Department of Chemistry, University of Rajasthan Jaipur-302 004 Fifteen new fluorine containing Mannich bases derived from 1,5-disubstituted-arylhydantoins have been synthesised by treating the appropriate 1,5-disubstituted-arylhydantoins with secondary amine and formaldehyde in ethanol. Seven 1,5-disubstituted-arylhydantoins were treated with chloroacetyl chloride and the resulting 3chloroacetyl-derivatives converted into the corresponding 3-dialkylaminoacetyl-1,5- disubstituted-arylhydantoins on treatment with secondary amines. Representative compounds have been screened

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6

Journal, Baghdad Science. "Synthesis of Some new 2-(4-Aryliminophenoxy)N-Arylacetamide Via p-hydroxy benzaldehyde." Baghdad Science Journal 11, no. 2 (2014): 486–90. http://dx.doi.org/10.21123/bsj.11.2.486-490.

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Chloroacetamide derivatives (2a-g) have been prepared through reaction of chloroacetyl chloride(1) (which prepared by the reaction of chloroacetic acid with thionyl chloride) with primary aromatic amines and sulfa compounds to afford compounds (2a-g) which then reacted with p-hydroxy benzaldehyde via Williamson reaction to obtaine the new compounds 2-(4-formyl phenoxy)-N-aryl acetamide (3a-g). Finally , compounds (3a-g) will be use as a good synthon to prepare the Schiff bases represented by compounds 2-(4-aryliminophenoxy)-N-arylacetamide (4a-g). through , reaction with some primary aromatic

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7

Kmal, Rafid Q., Shaimaa A. Behget, and Meaad N. Husean. "Synthesis and Characterization of Formazan Derivatives from Schiff’s Base and Studying their Biological Activity." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 12, no. 02 (2022): 782–88. http://dx.doi.org/10.25258/ijddt.12.2.56.

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A group of substituted formazine derivatives was prepared through several steps where the first step was the preparation of compound (1) by reacting chloroacetyl chloride with 2-aminopyrimidine, and the second step was the reaction of compound (1) with hydrazine hydrate to obtain the derivative (2) and in the third step was prepared Schiff’s base (3) by reaction of derivative (2) with para-dimethyl benzaldehyde and then a number of formazine derivatives were synthesized by reaction of derivative (3) with a number of substituted aromatic amines. The newly prepared derivatives are distinguished

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8

Zaki, Remon M., Adel M. Kamal El-Dean, Shaban M. Radwan, and Ahmed F. Saber. "Efficient synthesis, reactions and spectral characterization of pyrazolo[4’,3’:4,5]thieno[3,2-d] pyrimidines and related heterocycles." Heterocyclic Communications 25, no. 1 (2019): 39–46. http://dx.doi.org/10.1515/hc-2019-0004.

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AbstractNew pyrazolothienopyrimidines were synthesized. The key intermediate 4-aminothieno[2,3-c]pyrazole-5-carbonitrile 1 was converted to the chloroacetyl amino derivative 2 followed by nucleophilic substitution and Dimorth rearrangement upon treatment with nitrogen nucleophiles to give the pyrimidinones 3a-c. Treatment of 3a with formaldehyde and with triethyl orthoformate afforded the respective tetracyclic derivatives 4 and 5. Condensation of the amino group in the o-aminocarbonitrile 1 with triethyl orthoformate followed by cycloaddition reaction with hydrazine led to the formation of py

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9

Patel, H. S., H. D. Desai, and H. J. Mistry. "Synthesis and Antimicrobial Activity of Some New Piperazine Derivaties Containing Aryl Sulfonyloxy Group." E-Journal of Chemistry 1, no. 2 (2004): 93–98. http://dx.doi.org/10.1155/2004/732420.

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NovelN-substituted piperazine derivatives containing sulfonyloxy aniline moiety have been prepared. The various 4-sulfonyloxy aniline (SA) derivatives (2a-h) have been prepared by the condensation reaction ofN-Acetyl Sulfanilyl chloride (ASC) and sodium phenates followed by hydrolysis. The SA derivatives are then reacted with chloro acetyl chloride to give corresponding (N-Chloroacetyl) derivatives (3a-h). These derivatives are then reacted withN-phenyl piperazine to yield the corresponding piperazine derivatives (4a-h).

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10

Ammar Ferman Abbood, Ahmed M. Abdula, and Younis Baqi. "New Benzimidazoles Bearin 2-Pyrazoline Moiety: Synthesis and Antimicrobial Activity." Journal of Wasit for Science and Medicine 14, no. 3 (2023): 1–12. http://dx.doi.org/10.31185/jwsm.401.

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A new series of 5-(1H-Benzimidazol-2-yl)-4,5-dihydro-1H-pyrazol-3-yl] derivatives (1-9) were synthesized and characterized using spectral analysis. The first step includes the reaction of benzimidazole-2-carboxaldehyde with the o,p-aminoacetophenone to obtain the chalcone derivative (1, 2). The cyclization reaction of chalcone by the hydrazine hydrate afforded compound (3, 4), which represents the starting material for Schiff base derivatives. New Schiff bases (5-6) were synthesized from the reaction of benzimidazole derivative (2) with the corresponding benzaldehydes. The azetidin-2-one (7) a

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Book chapters on the topic "Chloroacetyl derivatives"

1

Tidwell, T. T. "Chloroketene by Pyrolytic Dehydrochlorination of Chloroacetyl Chloride." In Three Carbon-Heteroatom Bonds: Thio-, Seleno-, and Tellurocarboxylic Acids and Derivatives; Imidic Acids and Derivatives; Ortho Acid Derivatives. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-023-00099.

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2

Haider, N., and W. Holzer. "Cyclization of -Chloroacetyl Derivatives of 1,2-Dicarbonyl Monophenylhydrazones." In Six-Membered Hetarenes with Two Identical Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-016-00223.

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