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Journal articles on the topic 'Chloroquine'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Zdun, Sylwia, Klaudia Walczak, Weronika Gaweł, et al. "Side effects of long-term treatment with chloroquine for rheumatoid arthritis - a review of the literature." Journal of Education, Health and Sport 13, no. 2 (2022): 165–71. http://dx.doi.org/10.12775/jehs.2023.13.02.023.

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Background: Chloroquine is a 4-aminoquinoline derivative. Initially the substance was used as an antimalarial drug, but now chloroquine is also used to treat connective tissue diseases. It is a widely used drug in rheumatological diseases, especially in rheumatoid arthritis and systemic lupus erythematosus. A number of side effects have been reported in the public literature among patients using this drug. This article reviews side effects during long-term treatment of patients with rheumatoid arthritis. Materials and methods: A review of the literature available in the PubMed database was per

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2

ZDUN, Sylwia, Klaudia WALCZAK, Weronika GAWEŁ, et al. "Side effects of long-term treatment with chloroquine for rheumatoid arthritis - a review of the literature." Journal of Education, Health and Sport 13, no. 2 (2022): 165–71. https://doi.org/10.12775/JEHS.2023.13.02.023.

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<strong>ZDUN, Sylwia, WALCZAK, Klaudia, GAWEŁ, Weronika, WESOŁOWSKA, Zuzanna, JĘDRUSZCZAK, Przemysław, GRZYWNA, Natalia, NEMECZEK, Sylwia, MERKISZ, Konrad, GRZYBOWSKI, Jakub & WALCZAK, Patrycja. Side effects of long-term treatment with chloroquine for rheumatoid arthritis - a review of the literature</strong><strong>. Journal of Education, Health and Sport. 2023;13(2):1</strong><strong>65</strong><strong>-1</strong><strong>71</strong><strong>. eISSN 2391-8306. DOI </strong><strong>https://dx.doi.org/10.12775/JEHS.2023.13.02.02</strong><strong>3</strong> <strong>https://apcz.umk.pl/JEHS/art

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3

Blackard, W. G., R. M. Smith, and L. Jarett. "Insulin processing by cultured hepatocytes." American Journal of Physiology-Endocrinology and Metabolism 250, no. 2 (1986): E148—E155. http://dx.doi.org/10.1152/ajpendo.1986.250.2.e148.

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The chloroquine-sensitive and chloroquine-insensitive steps in insulin degradation by cultured hepatocytes have been explored by employing low temperature to retard processing. Under standard conditions (90 min association and 60 min dissociation) chloroquine inhibited insulin degradation at 15 degrees C but not at 37 degrees C. However, if the association and dissociation periods were short so that only early degradation was examined, marked inhibition of insulin degradation by chloroquine could also be observed at 37 degrees C. This inhibitory effect was observed only during the first 15 min

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4

Ridley, R. G., W. Hofheinz, H. Matile, et al. "4-aminoquinoline analogs of chloroquine with shortened side chains retain activity against chloroquine-resistant Plasmodium falciparum." Antimicrobial Agents and Chemotherapy 40, no. 8 (1996): 1846–54. http://dx.doi.org/10.1128/aac.40.8.1846.

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We have synthesized several 4-aminoquinolines with shortened side chains that retain activity against chloroquine-resistant isolates of Plasmodium falciparum malaria (W. Hofheinz, C. Jaquet, and S. Jolidon, European patent 94116281.0, June 1995). We report here an assessment of the activities of four selected compounds containing ethyl, propyl, and isopropyl side chains. Reasonable in vitro activity (50% inhibitory concentration, < 100 nM) against chloroquine-resistant P. falciparum strains was consistently observed, and the compounds performed well in a variety of plasmodium berghei animal

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5

FRANCO, YESENIA L., CHRISTINE KHAN, and SIHEM AIT-OUDHIA. "Pharmacodynamic Modeling Identifies Synergistic Interaction Between Chloroquine and Trastuzumab in Refractory HER2- positive Breast Cancer Cells." Cancer Diagnosis & Prognosis 3, no. 2 (2023): 175–82. http://dx.doi.org/10.21873/cdp.10198.

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Background/Aim: Despite improvements in HER2-positive breast cancer (BC) patients’ outcomes with trastuzumab, the occurrence of intrinsic or acquired resistance presents a clinical challenge. Here, we quantitatively assess the combinatorial effects of chloroquine, an autophagy inhibitor, with trastuzumab on JIMT-1 cells, a HER2-positive BC cell-line primarily resistant to trastuzumab. Materials and Methods: The temporal changes in JIMT-1 cellular viability were assessed using the CCK-8 kit, where JIMT-1 cells were exposed for 72-h to trastuzumab (0.007-17.19 μM) or chloroquine (5-50 μM) as sin

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6

&NA;. "Chloroquine see Proguanil/chloroquine." Reactions Weekly &NA;, no. 287 (1990): 6. http://dx.doi.org/10.2165/00128415-199002870-00013.

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7

Zhou, Qi, Xinzhou Yang, Mingrui Xiong, et al. "Chloroquine Increases Glucose Uptake via Enhancing GLUT4 Translocation and Fusion with the Plasma Membrane in L6 Cells." Cellular Physiology and Biochemistry 38, no. 5 (2016): 2030–40. http://dx.doi.org/10.1159/000445562.

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Background/Aims: Chloroquine can induce an increase in the cellular uptake of glucose; however, the underlying mechanism is unclear. Methods: In this study, translocation of GLUT4 and intracellular Ca2+ changes were simultaneously observed by confocal microscope in L6 cells stably over-expressing IRAP-mOrange. The GLUT4 fusion with the plasma membrane (PM) was traced using HA-GLUT4-GFP. Glucose uptake was measured using a cell-based glucose uptake assay. GLUT4 protein was detected by Western blotting and mRNA level was detected by RT-PCR. Results: We found that chloroquine induced significant

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8

&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1391 (2012): 16. http://dx.doi.org/10.2165/00128415-201213910-00057.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 696 (1998): 6. http://dx.doi.org/10.2165/00128415-199806960-00015.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 711 (1998): 7. http://dx.doi.org/10.2165/00128415-199807110-00020.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 726 (1998): 7. http://dx.doi.org/10.2165/00128415-199807260-00020.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 729 (1998): 7. http://dx.doi.org/10.2165/00128415-199807290-00020.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 741 (1999): 7. http://dx.doi.org/10.2165/00128415-199907410-00021.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 760 (1999): 6. http://dx.doi.org/10.2165/00128415-199907600-00013.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1166 (2007): 8. http://dx.doi.org/10.2165/00128415-200711660-00025.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1180 (2007): 10. http://dx.doi.org/10.2165/00128415-200711800-00027.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1189 (2008): 12. http://dx.doi.org/10.2165/00128415-200811890-00037.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1121 (2006): 9. http://dx.doi.org/10.2165/00128415-200611210-00026.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1148 (2007): 13. http://dx.doi.org/10.2165/00128415-200711480-00042.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1358 (2011): 12–13. http://dx.doi.org/10.2165/00128415-201113580-00042.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1359 (2011): 13. http://dx.doi.org/10.2165/00128415-201113590-00042.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1359 (2011): 13. http://dx.doi.org/10.2165/00128415-201113590-00043.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1364 (2011): 14. http://dx.doi.org/10.2165/00128415-201113640-00052.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1374 (2011): 13–14. http://dx.doi.org/10.2165/00128415-201113740-00038.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 546 (1995): 6. http://dx.doi.org/10.2165/00128415-199505460-00023.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 547 (1995): 4. http://dx.doi.org/10.2165/00128415-199505470-00006.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 559 (1995): 5. http://dx.doi.org/10.2165/00128415-199505590-00008.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 560 (1995): 7. http://dx.doi.org/10.2165/00128415-199505600-00014.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 564 (1995): 5. http://dx.doi.org/10.2165/00128415-199505640-00008.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 592 (1996): 5. http://dx.doi.org/10.2165/00128415-199605920-00013.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 432 (1992): 7. http://dx.doi.org/10.2165/00128415-199204320-00031.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 434 (1993): 7. http://dx.doi.org/10.2165/00128415-199304340-00025.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 445 (1993): 6. http://dx.doi.org/10.2165/00128415-199304450-00016.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 456 (1993): 6. http://dx.doi.org/10.2165/00128415-199304560-00028.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 468 (1993): 5. http://dx.doi.org/10.2165/00128415-199304680-00024.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 636 (1997): 6. http://dx.doi.org/10.2165/00128415-199706360-00017.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 650 (1997): 6. http://dx.doi.org/10.2165/00128415-199706500-00014.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 671 (1997): 8. http://dx.doi.org/10.2165/00128415-199706710-00018.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1406 (2012): 14–15. http://dx.doi.org/10.2165/00128415-201214060-00043.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1411 (2012): 15. http://dx.doi.org/10.2165/00128415-201214110-00050.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1412 (2012): 13–14. http://dx.doi.org/10.2165/00128415-201214120-00046.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1415 (2012): 15. http://dx.doi.org/10.2165/00128415-201214150-00053.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 388 (1992): 6. http://dx.doi.org/10.2165/00128415-199203880-00015.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 402 (1992): 6. http://dx.doi.org/10.2165/00128415-199204020-00019.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 405 (1992): 6. http://dx.doi.org/10.2165/00128415-199204050-00017.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 406 (1992): 6. http://dx.doi.org/10.2165/00128415-199204060-00015.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 419 (1992): 6. http://dx.doi.org/10.2165/00128415-199204190-00019.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1199 (2008): 16. http://dx.doi.org/10.2165/00128415-200811990-00046.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1203 (2008): 16. http://dx.doi.org/10.2165/00128415-200812030-00050.

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&NA;. "Chloroquine." Reactions Weekly &NA;, no. 1214 (2008): 11–12. http://dx.doi.org/10.2165/00128415-200812140-00029.

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