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Journal articles on the topic 'Cholekinetic'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Mirkin, A. "The value and use of black radish in internal medicine, mainly in diseases of the liver and biliary tract. Schräder Ztschr. f. Klin. Med. Bd. 121. H." Kazan medical journal 29, no. 3 (2021): 265. http://dx.doi.org/10.17816/kazmj86331.

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2

Gubergrits, N. B., and N. V. Byelyayeva. "Cholagogues: classic and modern." Herald of Pancreatic Club 66, no. 1 (2025): 51–61. https://doi.org/10.33149/vkp.2025.01.03.

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Cholagogues are among the most popular in clinical practice, although only hymecromone (Biloddi) has an evidence base. All cholagogues are divided into two categories: choleretics, which increase the liverʼs bile production, and cholekinetics, which increase the gallbladderʼs contractions and speed up the passage of bile from it into the duodenum. However, this division is arbitrary because cholagogues typically have both choleretic and cholekinetic effects, which are expressed to varying degrees in each drug and only prevail over each other. Hydrocholeretics are distinguished in the group of

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3

Chuchalin, V. S., and Ye M. Teplyakova. "Correction of hepatobiliary pathology by the complex herbal remedy." Bulletin of Siberian Medicine 6, no. 4 (2007): 46–52. http://dx.doi.org/10.20538/1682-0363-2007-4-46-52.

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The influence of complex herbal remedy on the secretary and metabolic functions of a liver was investigated in rates with experimental toxic hepatitis and hypercholesterolemia. The result obtained have shown that complex herbal remedy shortened the time of evolution and decreased hepatic enzymes (AST, ALT, and GGT), alkaline phosphates, total bilirubin, and cholesterol. It has also been shown that complex herbal remedy increased the protein synthesis of hepatocyte and hampered lipolysis processes. On the other hand, the active components of this remedy regulated the excessive bile production.

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4

Qayumov Feruz Sobir o'g'li and Tuxtayev Farhod Hakimovich. "Mineral analysis of dry extracts from the seeds of the plant Silybum marianum (L. Gaertner) introduced in Uzbekistan." International Journal on Integrated Education 3, no. 8 (2020): 235–37. http://dx.doi.org/10.31149/ijie.v3i8.573.

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Silybum marianum (L.) Gaerth. (Asteraceae) is a valuable medicinal plant In the domestic and foreign literature the following pharmacological properties of the medicinal forms from Silybum marianum are described: antioxidant, antitoxic, hemostatic, hepatoprotective, detoxification, choleretic, anti-inflammatory, wound healing, reparative, laxatives, tonic, improving digestion, cholekinetic, cholesecret [1,2]. In Uzbekistan, the development of products for functional and therapeutic-preventive purposes for preventing various diseases and strengthening protective functions body, reducing the ris

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5

Osyodlo, H. V., M. P. Boichak, and O. O. Fedorova. "Rational choice of hepatoprotectors for drug-induced liver injury." GASTROENTEROLOGY 56, no. 3 (2022): 179–89. http://dx.doi.org/10.22141/2308-2097.56.3.2022.507.

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The article deals with a review of the current literature on the clinical use of hepatoprotectors in drug-induced liver injury. The literature was searched in Scopus, Web of Science, PubMed and other databases. Risk factors, pathogenetic mechanisms of liver damage, international diagnostic criteria and treatment for drug-induced liver injuries are considered. Clinical and pharmacological approaches to the choice of hepatoprotectors for the management of drug-induced liver injury are substantiated. The positive effects of ademetionine, a hepatoprotector, are highlighted — choleretic, cholekine

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6

Kasztelan-Szczerbińska, Beata, Agnieszka Szczerbińska, and Halina Cichoż-Lach. "Hymecromone in the therapy of bile tract disorders and its new therapeutic perspectives – a literature review." Medycyna Faktów 15, no. 1 (2022): 85–91. http://dx.doi.org/10.24292/01.mf.0122.12.

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Hymecromone (4-methylumbelliferone; 7-hydroxy-4-methylcumarine) is a well-known drug effective in biliary tract disorders with a very favorable safety profile, which makes it readily used by doctors and patients. The medication has a unique three-phase mechanism of action which includes: choleretic – enhances the secretion of low-density bile; cholekinetic – stimulates the flow and excretion of bile to the intestines, and spasmolytic activity – reduces the tension of smooth muscles of the bile ducts as well as Oddi’s sphincter. In recent years, there have been reports on new features of hymecr

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7

Marfiyan, O. M., T. A. Korolyshyn, L. G. Barylyak, et al. "Neuroendocrine-immune and metabolic accompaniments of cholecystokinetic effects of balneotherapy on SPA Truskavets’." Journal of Education, Health and Sport 5, no. 5 (2015): 21–30. https://doi.org/10.5281/zenodo.17307.

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<strong>Marfiyan O</strong> <strong>M, Korolyshyn T</strong> <strong>A, Barylyak L</strong> <strong>G, </strong><strong>Kovbasnyuk M M, </strong><strong>Yavors’kyi O</strong> <strong>V,</strong> <strong>Zukow W,</strong> <strong>Popovych I</strong> <strong>L</strong><strong>. </strong><strong>Neuroendocrine-immune and metabolic accompaniments of cholecystokinetic effects of balneotherapy on SPA Truskavets’</strong><strong>. </strong><strong>Journal of Education, Health and Sport. </strong><strong>2015;5(5):21-30. ISSN 2391-8306. DOI: </strong><strong>10.5281/zenodo.17307</strong> <

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8

Lymanska, A. Yu. "“Reach the cells”: microcirculatory support." Infusion & Chemotherapy, no. 3.2 (December 15, 2020): 168–69. http://dx.doi.org/10.32902/2663-0338-2020-3.2-168-169.

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Background. Vessels of the microcirculatory tract provide regulatory, drainage, thermocontrol and signal functions. Disorders of these vessels are the part of the pathogenesis of coronary heart disease, endarteritis obliterans, Raynaud’s disease, etc. Common causes of microcirculation disorders include disorders of central and regional blood circulation, impaired blood volume and viscosity, impaired permeability of microvessel walls. Objective. To describe the features of microcirculatory support. Materials and methods. Analysis of literature sources on this topic. Results an

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9

Alyangin, V. G., V. U. Sataev, V. V. Viktorov, A. A. Nizhevich, and G. G. Latypova. "Features of diagnosis of cholelithiasis in children." Experimental and Clinical Gastroenterology, no. 11 (November 20, 2019): 59–63. http://dx.doi.org/10.31146/1682-8658-ecg-171-11-59-63.

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The aim was investigate some features of diagnosis of cholelithiasis in children. Materials and methods: The study was completed with 75 patients in the Clinic of pediatric surgery of the BSMU, Russia, Ufa in 1997-2017. The mean age of the patients was 11.2±3.8 (3-18) years. 44 (58.7%) patients were females. Results: The original method (X-ray Tomography with cholekinentic) was preferred and received results were decisive for surgery. Identified sclerotic changes (>40 H) and gallstone density (>100H) were indications for cholecystectomy.

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10

Popovych, Igor, Anatoliy Gozhenko, Myroslava Hrytsak, et al. "General non-specific effects of balneofactors of Truskavets’ spa on parameters of neuroendocrine regulation, metabolism, immunity and microbiota in patients with chronic pyelonephritis and cholecystitis." Journal of Education, Health and Sport 12, no. 1 (2022): 368–84. http://dx.doi.org/10.12775/jehs.2022.12.01.032.

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Background. Earlier in experiments on rats, it was shown that drinking mineral water, regardless of their mineralization and chemical composition, have similar (nonspecific) course effects on a number of parameters of metabolism and neuroendocrine-immune complex. The aim of this study is to identify such parameters in patients of Truskavets’ spa who received complex drinking balneotherapy. Materials and Methods. The object of clinical-physiological observation were 34 men aged 23-70 years, who underwent rehabilitation treatment of chronic cholecystitis and pyelonephritis in remission. The exam

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11

Hrytsak, Myroslava, Dariya Popovych, Sofiya Ruzhylo, Nataliya Zakalyak, and Walery Zukow. "Neuro-endocrine mechanism of specific balneoeffects of sulfate-chloride sodium-magnesium mineral waters." Journal of Education, Health and Sport 12, no. 3 (2022): 274–82. http://dx.doi.org/10.12775/jehs.2022.12.03.023.

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Background. Earlier we showed that the newly created sulfate-chloride sodium-magnesium drinking mineral waters “Myroslava” (5 g/L) and “Khrystyna” (10 g/L) have favorable effects on neuroendocrine-immune complex and metabolism of patients with their violations. At the same time, the influence of both waters on one constellation of parameters is similar, despite the twofold difference in mineralization, while on the other constellation it is different. The aim of this study was to elucidate the neuroendocrine mechanism of specific effects. Materials and Methods. The object of clinical-physiolog

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12

Kobeliatskyi, Yu Yu. "Infusion therapy of an oncologic patient: pros and cons." Infusion & Chemotherapy, no. 3.2 (December 15, 2020): 123–25. http://dx.doi.org/10.32902/2663-0338-2020-3.2-123-125.

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Background. The goals of infusion therapy (IT) include the restoration of adequate tissue perfusion, maintaining the quantity and quality of the body fluid sectors, correction of homeostasis parameters. In addition, IT can be used for parenteral nutrition, reducing the risk of thrombosis and urinary tract infections. Objective. To identify key IT parameters of a cancer patient. Materials and methods. Analysis of the available literature on this topic. Results and discussion. Indications for IT include hypovolemia, cellular and protein deficiency of blood, nutrition disorders,

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13

Struk, Zoryana D., Oksana I. Mel'nyk, Walery Zukow, and Igor L. Popovych. "Metabolic predictors of individual immune responses to adaptogenic balneotherapy." Journal of Education, Health and Sport 10, no. 2 (2020): 223–30. https://doi.org/10.5281/zenodo.3746282.

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<strong>Struk Zoryana</strong> <strong>D</strong><strong>.,</strong><strong> Mel</strong><strong>’</strong><strong>nyk Oksana</strong> <strong>I</strong><strong>.,</strong> <strong>Zukow Walery, Popovych Igor L. </strong><strong>Metabolic</strong> <strong>predictors</strong><strong> of individual immune responses to adaptogenic balneotherapy</strong><strong>. Journal of Education, Health and Sport. 2020;10(</strong><strong>2</strong><strong>):</strong><strong>223</strong><strong>-</strong><strong>230</strong><strong>. eISSN 2391-8306. DOI </strong><strong>ht

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14

Popovych, Igor, Anatoliy Gozhenko, Myroslava Hrytsak, Dariya Popovych, Nataliya Badiuk, and Walery Zukow. "Peculiarities of modulating effects of “Myroslava” and “Khrystyna” mineral waters on neuroendocrine-immune complex and metabolism in patients of Truskavets’ spa." Journal of Education, Health and Sport 12, no. 3 (2022): 53–66. http://dx.doi.org/10.12775/jehs.2022.12.03.005.

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Background. Earlier we found effects on the neuroendocrine-immune complex and metabolism, which are common to the mineral waters "Myroslava" and "Khrystyna", instead different from the effects of Naftussya water. The purpose of this article is to find the specific effects of these waters. Materials and Methods. The object of clinical-physiological observation were 22 men aged 23-70 years, who underwent rehabilitation treatment of chronic cholecystitis and pyelonephritis in remission in the Truskavets’ spa. The examination was performed twice, before and after a 7-10-day course of balneotherapy

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15

Bombushkar, Igor, Anatoliy Gozhenko, Ivan Savytskyi, et al. "Phytotea “ATINE” has beneficial effects on some neural, endocrine, immune, metabolic and biophysics variables in patients with maladaptation." Journal of Education, Health and Sport 82 (June 23, 2025): 62835. https://doi.org/10.12775/jehs.2025.82.62835.

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Background and aim. Earlier we shown that phytotea “ATINE” enhances the immunomodulatory effect of adaptogenic factors of the Truskavets’ Spa in patients after radical treatment of oncological pathology. It is known that the main component of the balneotherapy complex of the Truskavets’ Spa – Naftussya bioactive water (NBAW) – has its own modulating effect on the parameters of the neuro-endocrine-immune complex, metabolism, acupuncture and biophotonics. The purpose of this study is to find out how the combined use of NBAW with ATINE will affect such effects as well as to estimate the essential

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16

Popovych, Igor L., Anatoliy I. Gozhenko, Myroslava V. Hrytsak, et al. "General non-specific effects of balneofactors of Truskavets' spa on parameters of neuroendocrine regulation, metabolism, immunity and microbiota in patients with chronic pyelonephritis and cholecystitis." Journal of Education, Health and Sport 12, no. 1 (2022): 368–84. https://doi.org/10.12775/JEHS.2022.12.01.032.

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<strong>Popovych</strong> <strong>Igor L., Gozhenko Anatoliy I., Hrytsak Myroslava V., Popovych Dariya V., Korolyshyn Tetyana A.,</strong><strong> Kovbasnyuk Marta M.</strong><strong>, Zukow Walery</strong><strong>. </strong><strong>General non-specific effects of balneofactors of Truskavets’ spa on parameters of neuroendocrine regulation, metabolism, immunity and microbiota in patients with chronic pyelonephritis and cholecystitis</strong><strong>.</strong> <strong>Journal of Education, Health and Sport. 2022;12(1):</strong><strong>368</strong><strong>-</strong>

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17

Hrytsak, Myroslava V., Dariya V. Popovych, Sofiya V. Ruzhylo, Nataliya R. Zakalyak, and Walery Zukow. "Neuro-endocrine mechanism of specific balneoeffects of sulfate-chloride sodium-magnesium mineral waters." Journal of Education, Health and Sport 12, no. 3 (2022): 274–82. https://doi.org/10.12775/JEHS.2022.12.03.023.

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<strong>Hrytsak</strong> <strong>Myroslava V.,</strong><strong> Popovych</strong><strong> Dariya V.,</strong> <strong>Ruzhylo</strong><strong> Sofiya</strong> <strong>V</strong><strong>.,</strong> <strong>Zakalyak</strong> <strong>Nataliya</strong> <strong>R</strong><strong>.,</strong><strong> Zukow</strong> <strong>Walery</strong><strong>. </strong><strong>Neuro-endocrine mechanism of specific balneoeffects of sulfate</strong><strong>-chloride sodium-magnesium</strong><strong> mineral waters</strong><strong>.</strong> <strong>Jo

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18

Popovych, Igor L., Anatoliy I. Gozhenko, Myroslava V. Hrytsak, Dariya V. Popovych, Nataliya S. Badiuk, and Walery Zukow. "Peculiarities of modulating effects of "Myroslava" and "Khrystyna" mineral waters on neuroendocrine-immune complex and metabolism in patients of Truskavets' spa." Journal of Education, Health and Sport 12, no. 3 (2022): 53–66. https://doi.org/10.12775/JEHS.2022.12.03.005.

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<strong>Popovych</strong> <strong>Igor L., Gozhenko Anatoliy I., Hrytsak Myroslava V., Popovych</strong> <strong>Dariya V., Badiuk Nataliya S., Zukow Walery</strong><strong>. </strong><strong>Peculiarities of modulating effects of “Myroslava” and “Khrystyna” mineral waters on neuroendocrine-immune complex and metabolism in patients of Truskavets’ spa</strong><strong>.</strong> <strong>Journal of Education, Health and Sport. 2022;12(</strong><strong>3</strong><strong>):</strong><strong>53-66.</strong><strong> eISSN 2391-8306. DOI </strong><stron

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19

Strilchuk, L. M., L. V. Olenych, and O. M. Radchenko. "GALLBLADDER SIZES IN PATIENTS WITH ARTERIAL HYPERTENSION, OBESITY AND HYPOTHYROIDISM: CORRELATION ANALYSIS." Modern medical technologies 45, no. 2 (2020). http://dx.doi.org/10.34287/mmt.2(45).2020.7.

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Abstract Our previous studies showed that patients with arterial hypertension and excessive weight or obesity presented with the significantly enlarged gallbladder, both fasting and after taking cholekinetic. The gallbladder ejection fraction was below the normal range, and poor blood pressure control was accompanied by further gallbladder over distension, reduction of its contractility and increased risk of gallstone formation. This needs further research, especially considering hypothyreoidism. The aim is to establish correlations of the sonographically estimated gallbladder sizes in patient

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20

Ivanyts'ka, Oksana M., Tetyana G. Fedun, Vitaliy G. Velychko, et al. "Three types of gall-bladder motility at men with chronic cholecystitis and pyelonephritis and accompanying their parameters of kidney excretory function as well as metabolism." April 8, 2018. https://doi.org/10.5281/zenodo.1214876.

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<strong>Ivanyts’ka Oksana M, Fedun Tetyana G, Velychko Vitaliy G</strong><strong>,</strong> <strong>Safyanyk Tetyana V, Popel Svitlana L, Dudra Halyna Y, Zukow Walery. Three types of gall-bladder motility at</strong><strong> men with </strong><strong>chronic cholecystitis and pyelonephritis and accompanying their parameters of kidney excretory function as well as metabolism. </strong><strong>Journal of Education, Health and Sport. 2018;8(4):69-78. eISNN 2391-8306. DOI</strong><strong> http://dx.doi.org/10.5281/zenodo.1214876</strong> <strong>http://ojs.ukw.edu.pl/index.php/johs/article/v

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21

Ivanyts'ka, Oksana M., Roman I. Magdych, Tetyana V. Safyanyk, et al. "Features of neuroendocrine-immune complex by various types of gall-bladder motility at men with chronic cholecystitis and pyelonephritis." April 10, 2018. https://doi.org/10.5281/zenodo.1215859.

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<strong>Ivanyts’ka Oksana M, Magdych Roman I</strong><strong>,</strong> <strong>Safyanyk Tetyana V, Popel Svitlana L, Dudra Halyna Y, Ivashchenko Myroslava I, Zukow Walery. Features of neuroendocrine-immune complex by various types of gall-bladder motility at</strong><strong> men with </strong><strong>chronic cholecystitis and pyelonephritis</strong><strong>. Journal of Education, Health and Sport. 2018;8(4):99-106. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1215859</strong> <strong>http://ojs.ukw.edu.pl/index.php/johs/article/view/5409</strong> <strong>https://pbn.nauka.gov.p

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Marfiyan, Olena M., Walery Zukow, Milentyna V. Popovych, et al. "Relationships between parameters of gallbladder motility and brain electrical activity." August 2, 2016. https://doi.org/10.5281/zenodo.59271.

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<strong>Marfiyan Olena M</strong><strong>, </strong><strong>Zukow Walery, Popovych Milentyna V, Ganyk Lyubov M, Kit Yevgen I, Ivanyts’ka Oksana M, Kyjenko Valeriy M. Relationships between p</strong><strong>a</strong><strong>rame</strong><strong>t</strong><strong>e</strong><strong>rs</strong><strong> of gallbladder motility and brain electrical activity. </strong><strong>Journal of Education, Health and Sport. 2016;6(8):11-20. eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.5281/zenodo.59271</strong> <strong>http://ojs.ukw.edu.pl/index.php/johs/article/view/3728</strong> <stron

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