Academic literature on the topic 'Cholesterol treatment'

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Journal articles on the topic "Cholesterol treatment"

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Whyte, Martin B. "Is high-density lipoprotein a modifiable treatment target or just a biomarker for cardiovascular disease?" JRSM Cardiovascular Disease 8 (January 2019): 204800401986973. http://dx.doi.org/10.1177/2048004019869736.

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Epidemiological data strongly support the inverse association between high-density lipoprotein cholesterol concentration and cardiovascular risk. Over the last three decades, pharmaceutical strategies have been partially successful in raising high-density lipoprotein cholesterol concentration, but clinical outcomes have been disappointing. A recent therapeutic class is the cholesteryl ester transfer protein inhibitor. These drugs can increase circulating high-density lipoprotein cholesterol levels by inhibiting the exchange of cholesteryl ester from high-density lipoprotein for triacylglycerol
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Sheldon, T. A., F. Song, G. D. Smith, N. Freemantle, J. Mason, and A. Long. "Cholesterol screening and cholesterol lowering treatment." Quality and Safety in Health Care 2, no. 2 (1993): 134–37. http://dx.doi.org/10.1136/qshc.2.2.134.

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Gylling, H., S. Pyrhönen, E. Mäntylä, H. Mäenpää, L. Kangas, and T. A. Miettinen. "Tamoxifen and toremifene lower serum cholesterol by inhibition of delta 8-cholesterol conversion to lathosterol in women with breast cancer." Journal of Clinical Oncology 13, no. 12 (1995): 2900–2905. http://dx.doi.org/10.1200/jco.1995.13.12.2900.

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PURPOSE Long-term effects of tamoxifen and toremifene, a new antiestrogen that closely resembles tamoxifen, were investigated on serum lipids and cholesterol metabolism. PATIENTS AND METHODS The study group consisted of 24 postmenopausal Finnish women with advanced breast cancer from an international multicenter study of 415 patients. Cholesterol metabolism was evaluated by measuring the cholesterol precursor (delta 8-cholestenol, desmosterol, and lathosterol, reflecting cholesterol synthesis) and plant sterol (markers of cholesterol absorption) and cholestanol levels by gas-liquid chromatogra
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Reyhan, Cetinkaya, Yaldiz Mahizer, and Solak Berna. "Laboratory Tests Need for Plasma Lipids and Liver Enzymes During Oral IsotretioinTreatment." International Journal of Medical Reviews and Case Reports 3, no. 9 (2019): 578–80. https://doi.org/10.5455/IJMRCR.Oral-Isotretioin-Treatment.

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Acne is a chronic inflammatory condition of the pilosebaceous unit. Isotretinoin (ISO) is orally active retinoic acid derivative that is usually used to treat nodulocystic and conglobate types and resistant acne. Routine laboratory tests need when treating patients with ISO is controversal. We retrospectively collected data of 172 patients who received oral ISO for the treatment of acne vulgaris at the Dermatology Clinic of our institution and we examined biochemical parameters. When we compared pre-treatment and 3rd month treatment values in terms of serum levels of triglyceride, total choles
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Henney, J. E. "Elevated Cholesterol Treatment." JAMA: The Journal of the American Medical Association 284, no. 6 (2000): 685—a—685. http://dx.doi.org/10.1001/jama.284.6.685-a.

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Mayorek, N., та J. Bar-Tana. "Hypocholesterolaemic effect of β β'-methyl-substituted hexadecanedioic acid (MEDICA 16) in the male hamster". Biochemical Journal 289, № 3 (1993): 911–17. http://dx.doi.org/10.1042/bj2890911.

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Treatment of cholesterol-fed male hamsters kept on a diet of purina chow with beta beta'-methyl-substituted hexadecanedioic acid (MEDICA 16) resulted in a progressive hypocholesterolaemic effect, amounting to a 50% decrease in the cholesterol content of all plasma lipoproteins. The decrease in plasma cholesterol could be accounted for by activation of plasma-cholesterol efflux through the liver into the bile mediated by MEDICA 16-induced (a) increase of the number of liver LDL receptors, (b) activation of liver neutral cholesteryl ester hydrolase with a concomitant inhibition of liver acyl-CoA
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Bouillet, Benjamin, Thomas Gautier, Damien Denimal, et al. "Glucocorticoids impair HDL-mediated cholesterol efflux besides increased HDL cholesterol concentration: a proof of concept." European Journal of Endocrinology 183, no. 3 (2020): 297–306. http://dx.doi.org/10.1530/eje-20-0477.

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Objective: Glucocorticoids (GC) are associated with increased cardiovascular morbidity despite increased HDL-C concentration. HDL-mediated cholesterol efflux, a major anti-atherogenic property of HDL particles, is negatively associated with CVD risk. We aimed to determine whether HDL-mediated cholesterol efflux was influenced by GC. Design: Prospective, observational study. Methods: Lipid parameters, HDL composition, HDL-mediated cholesterol efflux, cholesteryl ester transfer protein, phospholipid transfer protein and lecithin cholesterol acyl-transferase (LCAT) activities were determined in t
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Martinez, Tania. "First Choice Lipid-Lowering Treatment of Hypercholesterolemias." Cardiology Research and Reports 3, no. 1 (2021): 01–05. http://dx.doi.org/10.31579/2692-9759/014.

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Several recent studies with lipid-lowering substances have shown a significant reduction in complications of this disease with drastic reduction of LDL-cholesterol levels. However, a huge proportion of patients in secondary prevention remain with inefficient treatment. Vastatins, also called statins, are considered worldwide as the first-line pharmacotherapy for the treatment of hypercholesterolemia, being the most efficient drugs to lower LDL-cholesterol, still presenting excellent tolerability. The main mechanism of action of vastatins is inhibition of the enzyme hydroxymethylglutaril-coenzy
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Torpy, Janet M. "Treatment of High Cholesterol." JAMA 291, no. 18 (2004): 2276. http://dx.doi.org/10.1001/jama.291.18.2276.

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Ganda, Om P. "Deciphering Cholesterol Treatment Guidelines." JAMA 313, no. 10 (2015): 1009. http://dx.doi.org/10.1001/jama.2015.216.

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Dissertations / Theses on the topic "Cholesterol treatment"

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Neubauer, Tamara E. "Cholesterol reduction in men : an experimental investigation of intensive treatment with frequent feedback versus a simple educational treatment /." Thesis, This resource online, 1990. http://scholar.lib.vt.edu/theses/available/etd-03122009-040807/.

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Wilson, Stephanie Helen. "Pathogenesis and treatment of cholesterol-related early vascular injury." Thesis, The University of Sydney, 2000. https://hdl.handle.net/2123/28453.

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This thesis describes studies into the pathogenesis of Cholesterol—related early vascular injury. In addition, this thesis examines the potential reversibility of this injury with 2 agents: a) simvastatin, an HMGCoA reductase inhibitor, in a model independent of any reduction in lipids and 2) high dose aspirin. Hypercholesterolaemia led to a decrease in NO bioavailability, in association with a decrease in the enzyme, endothelial nitric oxide synthase and increased oxidative stress. In addition, there was an increase in the pro—inflammatory transcription factor, NF—KB, in the intima o
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Volk, Catherine B. "Role of inhibition of protein prenylation in the cholesterol-dependent and cholesterol-independent effects of simvastatin." Virtual Press, 2006. http://liblink.bsu.edu/uhtbin/catkey/1339597.

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Statins are widely used to treat hypercholesterolemia. Statins inhibit cholesterol biosynthesis, thereby activating genes involved in cholesterol homeostasis, which are under the control of the Sterol Regulatory Element (SRE). Statins also have cholesterol-independent beneficial cardiovascular effects mediated through the phosphoinositide 3-kinase (PI3-K) / Akt signaling pathway and by inhibition of protein prenylation. Because statins inhibit the synthesis of isoprenoids, they can act by inhibiting the small signaling GTPases Ras and Rho, which require post-translational prenylation to become
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Hyttinen, L. (Laura). "Long-term effects of the cholesterol level and its drug treatment." Doctoral thesis, Oulun yliopisto, 2011. http://urn.fi/urn:isbn:9789514296222.

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Abstract Increased plasma cholesterol is a well-known risk factor for cardiovascular diseases in middle and early old age. At older ages, this association seems to disappear. Very few studies have assessed the impact of the lifelong cholesterol burden on old age, the purpose of this thesis. Study populations consisted of 1) old persons with familial hypercholesterolemia (FH), a genetic disorder associated with an increased risk of coronary heart disease (CHD) if untreated, and 2) initially healthy men (The Helsinki Businessmen Study, HBS) followed-up from midlife to old age. A population-based
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Lyu, Jun Fang. "Discovery of cholesterol trafficking inhibitors as novel anti-angiogenic and anti-cancer agents." Thesis, University of Macau, 2018. http://umaclib3.umac.mo/record=b3953967.

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Starck, Lena. "Smith-Lemli-Opitz syndrome - a disorder of cholesterol synthesis : diagnosis, treatment and pathogenetic aspects /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-273-6.

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Niven, Stewart James. "The origins and occurrence of estrogenic A-ring aromatic steroids in U.K. sewage treatment works effluents." Thesis, University of Plymouth, 1999. http://hdl.handle.net/10026.1/2157.

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There is worldwide concern over the possible estrogenic effects of organic chemicals on a variety of wildlife and indeed on humankind. In the U.K., estrogenic compounds in sewage treatment works (STW) effluents have been implicated in causing the increases in egg yolk protein production observed in caged male trout and other fish species. At the initiation of the present study, few of the estrogenic compounds in STW effiuents had been recognised, although circumstantial evidence suggested that steroidal hormones were primary candidates. Cholesterol is abundant in STW effluents and is the precu
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Vanstone, Catherine A. "Influence of phytosterols versus phytostanols on plasma lipid levels and cholesterol metabolism in hypercholesterolemic humans." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33854.

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The objective of this research was to examine the effects of sitosterol and sitostanol supplementation on plasma cholesterol levels and cholesterol metabolism in hypercholesterolemic subjects consuming a fixed foods diet in a four-phase crossover design. It was hypothesized that addition of either phytosterols, phytostenols, or a 50:50 mixture of sterols and stanols to butter would reduce circulating cholesterol levels, despite butter's hypercholesterolemic effect, through actions involving cholesterol absorption, synthesis, and turnover rates. The data obtained indicate that in their free, un
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Altemus, Jessica B. "Induction of Liver Abcg5/Abcg8 Expression is an Important Determinant of the Macrophage-to-Feces Reverse Cholesterol Transport Response to Treatment with Ezetimibe." Cleveland State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=csu1366662840.

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Hambræus, Kristina. "From Stenting to Preventing : Invasive and Long-term Treatment for Coronary Artery Disease in Sweden." Doctoral thesis, Uppsala universitet, Institutionen för medicinska vetenskaper, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-233167.

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Coronary artery disease (CAD) is the leading cause of death worldwide. Treatment with coronary interventions, long-term treatment and life style changes can reduce symptoms and improve prognosis. The aim of this thesis was to investigate aspects of invasive treatment for multivessel coronary artery disease, and to investigate adherence to prevention guidelines one year after myocardial infarction.  We used the national quality registry SWEDEHEART to collect data on long term treatment one year after myocardial infarction for 51 620 patients < 75 years of age. For 17 236 of the patients, we
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Books on the topic "Cholesterol treatment"

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National Heart, Lung, and Blood Institute and National Cholesterol Education Program (U.S.). Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults, eds. Cholesterol treatment recommendations for adults: Highlights of 1987 report, National Cholesterol Education Program Adult Treatment Panel. National Heart, Lung, and Blood Institute, 1987.

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Saskatchewan. Health Services Utilization and Research Commission., ed. Cholesterol testing and treatment in adults: Final report. Health Services Utilization and Research Commission, 1995.

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NHS Centre for Reviews & Dissemination. and FT Healthcare, eds. Cholesterol and coronary heart disease: Screening and treatment. NHS Centre for Reviews and Dissemination, University of York, in association with FT Healthcare, 1998.

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National Cholesterol Education Program (U.S.). Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Second report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (adult treatment panel II). National Cholesterol Education Program, National Institute of Health, National Heart, Lung, and Blood Institute, 1993.

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National Cholesterol Education Program (U.S.), ed. Second report of the expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel II). National Cholesterol Education Program, National Institute of Health, National Heart, Lung, and Blood Institute, 1993.

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Office, General Accounting. Cholesterol treatment: A review of the clinical trials evidence : report to the Ranking Minority Member, Committee on Science, House of Representatives. The Office, 1996.

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Office, General Accounting. Cholesterol treatment: A review of the clinical trials evidence : report to the Ranking Minority Member, Committee on Science, House of Representatives. The Office, 1996.

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National, Cholesterol Education Program (U S. ). Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults. Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (adult treatment panel III): Final report. The Program, 2002.

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National Cholesterol Education Program (U.S.), ed. Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (adult treatment panel III): Executive summary. National Cholesterol Education Program, National Heart, Lung, and Blood Institute, National Institutes of Health, 2001.

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National Institutes of Health (U.S.). So you have high blood cholesterol. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, 1992.

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Book chapters on the topic "Cholesterol treatment"

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Møller, Jens. "Treatment of CVD with Testosterone." In Cholesterol. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71600-3_19.

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Hennekens, C. H., E. H. Lieberman, M. H. Rubenstein, P. R. Hebert, D. L. DeMets, and M. A. Pfeffer. "9. Statins in the treatment and prevention of cardiovascular diseases." In Handbook of cholesterol. Wageningen Academic Publishers, 2016. http://dx.doi.org/10.3920/978-90-8686-821-6_9.

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Diaz-Stransky, Andrea, and Elaine Tierney. "Cholesterol Use in Autism Treatment." In Comprehensive Guide to Autism. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-4788-7_147.

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Song, Tae-Jin. "Cholesterol Management After Stroke." In Stroke Revisited: Diagnosis and Treatment of Ischemic Stroke. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-1424-6_26.

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Kelley, Richard I., and Lisa Kratz. "Cholesterol Synthesis Disorders." In Physician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-40337-8_36.

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Kratz, Lisa E., and Richard I. Kelley. "Disorders of Cholesterol Biosynthesis." In Physician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-67727-5_54.

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Fleming, Richard M. "Cholesterol, Triglycerides, and the Treatment of Hyperlipidemias." In Textbook of Angiology. Springer New York, 2000. http://dx.doi.org/10.1007/978-1-4612-1190-7_30.

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Kronenberg, Florian. "Lipoprotein(a)." In Prevention and Treatment of Atherosclerosis. Springer International Publishing, 2021. http://dx.doi.org/10.1007/164_2021_504.

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AbstractLipoprotein(a) [Lp(a)] is an atherogenic lipoprotein with a strong genetic regulation. Up to 90% of the concentrations are explained by a single gene, the LPA gene. The concentrations show a several-hundred-fold interindividual variability ranging from less than 0.1 mg/dL to more than 300 mg/dL. Lp(a) plasma concentrations above 30 mg/dL and even more above 50 mg/dL are associated with an increased risk for cardiovascular disease including myocardial infarction, stroke, aortic valve stenosis, heart failure, peripheral arterial disease, and all-cause mortality. Since concentrations abov
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Leuschner, U., H. Baumgärtel, W. Kurtz, M. Leuschner, and W. D. Strohm. "Medical Treatment of Cholesterol Gallstones: Present and Future." In Assessment and Management of Hepatobiliary Disease. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-72631-6_15.

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Lirussi, Flavio, Rosa Maria Iemmolo, Rocco Orlando, et al. "Bile Acid Treatment of Cholesterol Gallstones: A Reappraisal." In Assessment and Management of Hepatobiliary Disease. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-72631-6_16.

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Conference papers on the topic "Cholesterol treatment"

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Norϕ, A., T. Smimonsen, K. Ytre-Arene, B. Lyngmo, and B. Svensson. "THE EFFECT OF TWO CHOLESTEROL-LOWERING AGENTS ON PLATELETS IN PATIENTS WITH HYPERCHOLESTEROLEMIA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643801.

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Twenty-one subjects with type Ila hyperlipoproteinemia, receiving dietary treatment were given Synvinolin (MK-733), a HMG-CoA reductase inhibitor, 40 mg or Cholestyramin (Questran) 24 g daily for a period of 12 weeks.Serum lipids, platelet cholesterol, phospholipids and fatty acid composition and platelet function were measured before and after the intake of the two drugs.Both drugs reduced serum total cholesterol with approximately 50%. No significant changes were observed in platelet lipid concentrations or in the primary bleeding time. Collagen induced aggregation and thromboxane (TXA2) pro
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Mitropoulos, K. A., S. J. Walter, T. W. Meade, and M. P. Esnouf. "INCREASED FACTOR VII REACTIVITY IN THE RABBIT FOLLOWING DIET-INDUCED HYPERCHOIESTEROIAEMIA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643802.

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The association of factor VII coagulant activity (VIIC) with plasma lipid concentrations has been a consistent feature of a number of studies in man and points to plasma lipoproteins as determinants of VIIC.To modify plasma lipoprotein concentrations and to study the effect of this on VIIC, rabbits were fed a 1%- cholesterol-supplemented diet. Treatment resulted in a many-fold increase in plasma cholesterol concentration with the major fraction of excess cholesterol associated with the very low and intermediate density lipoprotein fractions. VIIC was considerably higher in rabbits fed 1%- chol
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Lucke-Wold, Brandon, Maya Fleseriu, Haley Calcagno, Timothy Smith, Joshua Levy, and Jeremy Ciporen. "A Minimally Invasive Approach for Treatment of Cholesterol Granuloma of the Petrous Apex." In 29th Annual Meeting North American Skull Base Society. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1679594.

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Bachkova, I. K., I. V. Chernikov, A. V. Sen’kova, et al. "CHOLESTEROL-CONJUGATED SMALL INTERFERING RNA TARGETING IL6 ALLEVIATES ACUTE LUNG INJURY IN MICE." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-285.

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Inflammatory diseases affect a substantial portion of the global population, and the current treatment is not universally effective. We demonstrate that locally administered cholesterol-conjugated siRNA targeting Il6 alleviates the symptoms of acute lung injury, which makes it a promising strategy for the treatment of inflammatory diseases with potential applications beyond the lungs.
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Marrero, Wesley J., Mariel S. Lavieri, and Jeremy B. Sussman. "A Simulation Model to Evaluate the Implications of Genetic Testing in Cholesterol Treatment Plans." In 2019 Winter Simulation Conference (WSC). IEEE, 2019. http://dx.doi.org/10.1109/wsc40007.2019.9004735.

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Gangadharan, N., P. Kavanagh, PT Wash та ін. "2 Cholesterol crystal secretion of IL-1β from PBMCS is reduced with simvastatin treatment". У The Scottish Cardiovascular Forum 2018, 3rd February 2018, Trinity Biomedical Science Institute, Trinity College Dublin Ireland. BMJ Publishing Group Ltd and British Cardiovascular Society, 2018. http://dx.doi.org/10.1136/heartjnl-2018-scf.12.

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Tahseen Taha AL-TAEE, Nidhal. "EFFECT OF FATTY EXTRACT OF AZOLLA PLANT WITH DIFFERENT SOLVENTS ON HEMATOLOGICAL AND BIOCHEMICAL PARAMETERS OF COMMON CARP CYPRINUS CARPIO L." In VI.International Scientific Congress of Pure,Applied and Technological Sciences. Rimar Academy, 2022. http://dx.doi.org/10.47832/minarcongress6-51.

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The study was conducted in the fish laboratory of the Department of Animal Production in the College of Agriculture and Forestry / the University of Mosul. The experiment included feeding common carp fish using ten experimental diets containing Azolla plant extract at percentages (0.5%, 1%, 1.5%) of each solvent, ether, acetone, and ethanol, and the control was free of additives. Glass tanks were used in the growth experiment of carp fish for a period of 49 days. The results of the statistical analysis showed that the average hemoglobin concentration and the percentage of the volume of compact
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Li, Junjie, Seung-Young Lee, Dongsheng Gu, et al. "Abstract B50: Abrogating cholesterol esterification suppresses pancreatic cancer growth and metastasis mediated by caveolin-1." In Abstracts: AACR Special Conference on Pancreatic Cancer: Innovations in Research and Treatment; May 18-21, 2014; New Orleans, LA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.panca2014-b50.

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Lee, Sang Y., Becky Slagle-Webb, Cara-Lynne Schengrund, and James Connor. "Abstract 4065: Association study between iron and cholesterol for the treatment of drug resistant neuroblastoma." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-4065.

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Albanell, M., L. Aranda, N. Fernández, et al. "3PC-001 Cholesterol 2%/simvastatin 1% ointment for the treatment of porokeratosis ptychotropica: a case report." In 26th EAHP Congress, Hospital pharmacists – changing roles in a changing world, 23–25 March 2022. British Medical Journal Publishing Group, 2022. http://dx.doi.org/10.1136/ejhpharm-2022-eahp.28.

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Reports on the topic "Cholesterol treatment"

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Lawanprasert, Somsong, Chaiyo Chaichantipyuth, Supatra Srichairat, Nuansri Niwattisaiwong, and Laddawal Phivthong-ngam. Subchronic exposure of Pueraria mirifica in normal - and high cholesterol diet fed rats : influence on hepatic cytochrome P450, lipid profile and toxicity. Chulalongkorn University, 2004. https://doi.org/10.58837/chula.res.2004.28.

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Pueraria mirifica airy shaw and suvatabandhu, know locally as Kwao Keur, is a plant in family Leguminosae. In this study, effects of P.mirifica on hepatic cytochrome P450 (CYP), serum lipid profile and subchronic toxicity were investigated in male Wistar rats. Rats were randomly divided into four treatment groups as following: normal diet-fed group; normal diet-fed supplemented with P.mirifica group; high cholesterol diet-fed group; high cholesterol diet-fed supplemented with P.mirifica group. Each group comprised 10 rats. P.mirifica was administered orally at a dosage of 100 mg/kg/day for 90
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yu, luyou, jinping yang, xi meng, and yanhua lin. Effectiveness of the gut microbiota-bile acid pathway (BAS) in the treatment of Type 2 diabetes: A protocol for systematic review and meta analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.7.0117.

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Review question / Objective: To systematically evaluate the efficacy of the intestinal microbiome - bile acid pathway (BAS) in the treatment of T2DM. Condition being studied: Bile acids (BAs), an important component of bile, are also metabolites derived from cholesterol and promote intestinal absorption and transportation of dietary lipids . Studies have shown that bile acid receptor agonists can promote glP-1 secretion and improve glucose metabolism in preclinical mouse models of obesity and insulin resistance , which may become a new therapeutic target for Type 2 diabetes. However, no system
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Chen, Jiankun, Yingming Gu, Lihong Yin, et al. Network meta-analysis of curative efficacy of different acupuncture methods on obesity combined with insulin resistance. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.8.0075.

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Review question / Objective: Population:Patients diagnosed as obesity with insulin resistance. Obesity reference: Consensus of experts on the Prevention and treatment of adult obesity in China in 2011 and Consensus of Chinese experts on medical nutrition therapy for overweight/obesity in 2016 were developed by the Obesity Group of Chinese Society of Endocrinology(CSE); BMI≥28. IR reference: According to the Expert opinions on insulin resistance evaluation published by Chinese Diabetes Society, HOMA-IR≥2.68 is regarded as the standard for the diagnosis of IR. Regardless of age, gender and cours
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Meidan, Rina, and Robert Milvae. Regulation of Bovine Corpus Luteum Function. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7604935.bard.

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The main goal of this research plan was to elucidate regulatory mechanisms controlling the development, function of the bovine corpus luteum (CL). The CL contains two different sterodigenic cell types and therefore it was necessary to obtain pure cell population. A system was developed in which granulosa and theca interna cells, isolated from a preovulatory follicle, acquired characteristics typical of large (LL) and small (SL) luteal cells, respectively, as judged by several biochemical and morphological criteria. Experiments were conducted to determine the effects of granulosa cells removal
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The benefits of commonly used blood pressure and cholesterol lowering treatment can last 16 years. National Institute for Health Research, 2019. http://dx.doi.org/10.3310/signal-000710.

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