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Journal articles on the topic 'Choosing of variants'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

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1

Misho, Matsankov, and Ivanova Mihaela. "Selection of Optimal Variant of Hybrid System under Conditions of Uncertainty." E3S Web of Conferences 115 (2019): 01007. http://dx.doi.org/10.1051/e3sconf/201911501007.

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The aim of the study is to select an optimal variant of a hybrid system under conditions of uncertainty according to selected criteria. The problems of the study are the different options for building the hybrid system and choosing an adequate criterion for choosing the optimal variant. The study covers analysis of three variants of building up a hybrid system for supplying of autonomous electric load. The three variants are: introduction of an active user for equalizing the load schedule; introduction of additional generating source for covering the peak portion of the load schedule; covering

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2

Cohen, Jonathan. "Perceptual variation, realism, and relativization, or: How I learned to stop worrying and love variations in color vision." Behavioral and Brain Sciences 26, no. 1 (2003): 25–26. http://dx.doi.org/10.1017/s0140525x03260015.

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AbstractIn many cases of variation in color vision, there is no nonarbitrary way of choosing between variants. Byrne & Hilbert insist that there is an unknown standard for choosing, whereas eliminativists claim that all the variants are erroneous. A better response relativizes colors to perceivers, thereby providing a color realism that avoids the need to choose between variants.

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Bucoń, Robert, and Anna Sobotka. "DECISION-MAKING MODEL FOR CHOOSING RESIDENTIAL BUILDING REPAIR VARIANTS." Journal of Civil Engineering and Management 21, no. 7 (2015): 893–901. http://dx.doi.org/10.3846/13923730.2014.895411.

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During the use of buildings it becomes necessary to carry out repair works including modernisation. Deciding on the choice of repair solutions is a difficult and complex task. Building administrators have to consider both, the benefits of some repair works, and limitations due to the availability of funds. Selection of a repair solution, bearing in mind the above, requires a comprehensive approach that will allow assessment of the building condition and determining the repair scope required. The research conducted by the authors was aimed at developing a decision-making model and its computer-

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Záboj, M. "Choosing the distribution channel for meat products." Agricultural Economics (Zemědělská ekonomika) 48, No, 7 (2012): 327–31. http://dx.doi.org/10.17221/5329-agricecon.

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In the paper, the author deals with the problem of choosing the distribution channel and offers the use of selected methods which should contribute to the final distribution process decision for the firm pursuing production and sale of meat and smoked goods. It is direct qualitative estimate approach, weighted factor summing approach and distribution cost approach. The last two methods try to quantify the decision criteria. In case of the weighted factor summing approach, the weights are assigned to each of the decision factors and at the same time each channel alternative is rated and the ove

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Żabicki, Piotr, and Władysław Gardziejczyk. "Selected aspects of multicriteria analysis in the design of bypass roads." Budownictwo i Architektura 13, no. 1 (2014): 213–22. http://dx.doi.org/10.35784/bud-arch.1941.

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The multicriteria analysis is a method of supporting the decision process in a situation where there are many road alignment variants analyzed. The paper presents two examples of choosing the most beneficial variant for bypassing a town, located in the course of regional roads. The analysis was conducted basing on normalization methods by Van Delft and Nijkamp, Weitendorf, Peldschus and the weight of the considered criteria. The considered criteria describing the analyzed variants are usually expressed in different units. The use of normalization is necessary to achieve the comparability of th

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Pavlovic, Katarina, Vojislav Bozanic, Jasna Stanojevic, Vesna Milicevic, and Bojan Ilic. "Laboratory testing of hemolytic properties of materials that come in contact with blood: Comparative application testing method’s two variants according to the standard ASTM F756 in accordance with ISO 10993-4." Chemical Industry 64, no. 2 (2010): 149–56. http://dx.doi.org/10.2298/hemind100225010p.

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The presence of hemolytic material in contact with blood may produce increased levels of blood cell lysis and increased levels of plasma hemoglobin. This may induce toxic effects or other effects which may stress the kidneys or other organs. In this paper two variants of in vitro method and obtained results? comparison were presented for testing of hemolytic properties of six raw materials (Polipropylene Moplen EP 540 P, Policarbonate colorless 164 R-112, Policarbonate brown 164 R-51918, Polietylene NG 3026 K, Polietylene NG - Purell GB 7250, Polietylene VG - Hiplex 5502) for medical device ma

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Berankova, Eva, František Kuda, and Stanislav Endel. "Preparation of Sub-Criteria for Mathematical Modeling of Multi-Criteria Decision Making." Advanced Materials Research 1020 (October 2014): 765–68. http://dx.doi.org/10.4028/www.scientific.net/amr.1020.765.

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The subject of this paper is to evaluate criteria in the decision-making process for choosing new usable office facilities in light of a big company or public service seeking for new usable office facilities. The criteria defining the requirements for individual selection variants enter into this decision-making process. These criteria have qualitative and quantitative characters. In order to model the criteria, it is desirable that their values are standardized. The method of standardization of these criteria is given in this paper. In this paper, attention is paid to the decision-making proc

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Acosta-Herrera, Marialbert, David González-Serna, and Javier Martín. "The Potential Role of Genomic Medicine in the Therapeutic Management of Rheumatoid Arthritis." Journal of Clinical Medicine 8, no. 6 (2019): 826. http://dx.doi.org/10.3390/jcm8060826.

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During the last decade, important advances have occurred regarding understanding of the pathogenesis and treatment of rheumatoid arthritis (RA). Nevertheless, response to treatment is not universal, and choosing among different therapies is currently based on a trial and error approach. The specific patient’s genetic background influences the response to therapy for many drugs: In this sense, genomic studies on RA have produced promising insights that could help us find an effective therapy for each patient. On the other hand, despite the great knowledge generated regarding the genetics of RA,

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Belovalova, Irina M., Natalya Yu Sviridenko, Elena G. Bessmertnaya, Anna A. Chepurina, Marina S. Sheremeta, and Alexander A. Mikheenkov. "Phenotypes of endocrine ophthalmopathy: clinical manifestation and tomographic characteristics." Problems of Endocrinology 64, no. 6 (2019): 383–89. http://dx.doi.org/10.14341/probl9618.

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The clinical manifetstations of endocrine orbitopathy (EOP) significantly because autoimmune process may involve various anatomical structures of the eye. Choosing an effective method for EOP treatment requires to determine the selectivity of orbital tissue damage, which is difficult when only clinical criteria are applied. 102 patients with EOP and Graves’ disease were examined. All patients underwent the standard ophthalmological examination and multispiral computed tomography of orbits. The analysis of clinical and tomographic parameters allowed us to distinguish 3 variants of EOP flow: cla

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van der Lee, Maaike, Marjolein Kriek, Henk-Jan Guchelaar, and Jesse J. Swen. "Technologies for Pharmacogenomics: A Review." Genes 11, no. 12 (2020): 1456. http://dx.doi.org/10.3390/genes11121456.

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The continuous development of new genotyping technologies requires awareness of their potential advantages and limitations concerning utility for pharmacogenomics (PGx). In this review, we provide an overview of technologies that can be applied in PGx research and clinical practice. Most commonly used are single nucleotide variant (SNV) panels which contain a pre-selected panel of genetic variants. SNV panels offer a short turnaround time and straightforward interpretation, making them suitable for clinical practice. However, they are limited in their ability to assess rare and structural vari

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Rost, Simone, Konstantin Kolokotronis, Gerhard Meng, Natalie Pluta, Clemens Müller-Reible, and Wolfram Kress. "The Genetic Approach: Next-Generation Sequencing-Based Diagnosis of Congenital and Infantile Myopathies/Muscle Dystrophies." Neuropediatrics 48, no. 04 (2017): 242–46. http://dx.doi.org/10.1055/s-0037-1602660.

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AbstractThe practical basis for massive parallel sequencing is described to help clinicians in choosing the most adequate diagnostic approach for childhood myopathies. The key quality feature for massive parallel sequencing is the sequence depth (coverage) as a prerequisite for variant identification and quantification of sequence copy numbers. Our experience with a next-generation sequencing gene panel for the analysis of muscular dystrophies/myopathies with infantile or juvenile onset resulted in the identification of pathogenic or likely pathogenic mutations in approximately 41% (of 141 pat

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Onslow, Mark. "Choosing a Treatment Procedure for Early Stuttering." Journal of Speech, Language, and Hearing Research 35, no. 5 (1992): 983–93. http://dx.doi.org/10.1044/jshr.3505.983.

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The new responsibility of speech-language pathologists to provide direct, early intervention for stuttering creates a further responsibility for them to choose justifiable treatment procedures for that intervention. This paper has two purposes. The first is to encourage clinicians to evaluate the conceptual and practical aspects of the treatments they use for early stuttering. The second purpose of the paper is to overview available early intervention procedures and consider the advantages, disadvantages, and prominent issues associated with each. The procedures considered are environment mani

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Vindeker, A. V. "Study of declination methods while forming the appearance of the surface-to-air unmanned aerial vehicle with a vertical start." Civil Aviation High Technologies 24, no. 3 (2021): 57–70. http://dx.doi.org/10.26467/2079-0619-2021-24-3-57-70.

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The problem of choosing a rational declination system from alternative variants at the stage of forming the appearance of an unmanned aerial vehicle (UAV) with a vertical launch is considered. Currently, the vertical launch is becoming more widely used for surface-to-air unmanned aerial vehicles, which are considered in this paper. A characteristic initial part of the trajectory of such unmanned aerial vehicles is the declination to the required angular position over a short period of time. The UAV declination process requires the generation of relatively large control moments. Declination of

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Petrikeeva, Natalya, Yekaterina Kopytina, Galina Martynenko, and Victoria Kozlova. "Application of game theory when taking decisions and choosing the best variant." E3S Web of Conferences 164 (2020): 08027. http://dx.doi.org/10.1051/e3sconf/202016408027.

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The paper is devoted to a new way of determining optimal distribution of resources in performing construction and assembly work. Properly analyzed territorial features of the construction site, the local topography and housing density, the degree of the system reliability, available resources, and options for carrying out work may help reduce construction costs. That may be done after choosing the best variant relying on a number of criteria, which is one of the main goals for any organization and one of the main principles of efficient use of resources. As a simulation of this situation, it i

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Malinauskas, Pranas, and Darius Kalibatas. "THE SELECTION OF RATIONAL CONSTRUCTIONAL TECHNOLOGY PROCESSES VARIANTS USING COPRAS METHOD." Technological and Economic Development of Economy 11, no. 3 (2005): 197–205. http://dx.doi.org/10.3846/13928619.2005.9637699.

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The article analyses the manner of selection an optimal building technological project which would pander the majority of the concerned members (architects, customers, designers, contractors and so on) interests. Assessment technique is being considered and its features as well. The need to value the expenses associated not only with the construction period, but also with the exploitation period is explaned. A few examples are given about choosing a rational project considering not only the cost, but also some value factors that influence job quality or exploitation.

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Tagg, Caroline, Alistair Baron, and Paul Rayson. "“i didn’t spel that wrong did i. Oops”." SMS Communication: A linguistic approach 35, no. 2 (2012): 367–88. http://dx.doi.org/10.1075/li.35.2.12tag.

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Spelling variation, although present in all varieties of English, is particularly prevalent in SMS text messaging. Researchers argue that spelling variants in SMSes are principled and meaningful, reflecting patterns of variation across historical and contemporary texts, and contributing to the performance of social identities. However, little attempt has yet been made to empirically validate SMS spelling patterns (for most languages, with the notable exception of French) and verify the extent to which they mirror those in other texts. This article reports on the use of the VARD2 tool to analys

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Tarnovskaya, Svetlana I., Anna A. Kostareva, and Boris S. Zhorov. "L-Type Calcium Channel: Predicting Pathogenic/Likely Pathogenic Status for Variants of Uncertain Clinical Significance." Membranes 11, no. 8 (2021): 599. http://dx.doi.org/10.3390/membranes11080599.

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(1) Background: Defects in gene CACNA1C, which encodes the pore-forming subunit of the human Cav1.2 channel (hCav1.2), are associated with cardiac disorders such as atrial fibrillation, long QT syndrome, conduction disorders, cardiomyopathies, and congenital heart defects. Clinical manifestations are known only for 12% of CACNA1C missense variants, which are listed in public databases. Bioinformatics approaches can be used to predict the pathogenic/likely pathogenic status for variants of uncertain clinical significance. Choosing a bioinformatics tool and pathogenicity threshold that are optim

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Strukov, Konstantin, Irina Nikiforova, Vladimir Lavenkov, and Yuri Iun. "Choosing the method of excavating vein reserves and mineralized zones on the basis of simulation modeling." E3S Web of Conferences 56 (2018): 01018. http://dx.doi.org/10.1051/e3sconf/20185601018.

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For the effective involvement of off-balance ores into development, a simulation modeling of gross and selective mining variants at "Kochkar" deposit reserves has been carried out by the Monte Carlo method, provided that a new type of geological resource - mineralized rocks has been involved in mining, and an economic evaluation of competing options has been made.

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VUKOLOV, Vladimir Yu, Anton A. KOLESNIKOV, Mikhail D. OBALIN, and Boris V. PAPKOV. "Choosing the Order of Renovation of Relay Protection Devices by Using Statistical Criteria of Game Theory." Elektrichestvo 5, no. 5 (2021): 26–32. http://dx.doi.org/10.24160/0013-5380-2021-5-26-32.

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There are many cases of incorrect work of relay protection due to the fact that most of the using devices are outdated. However, it is difficult to make a comprehensive replacement of all protections with modern ones due to the lack of funding and the high cost of modern devices. Therefore, an important task is to develop ways to solve this issue in the conditions of partial uncertainty of the initial information. An approach using game theory is considered that allows planning a reconstruction of relay protection with a limited budget and minimal risk. The choice of one of two variants for th

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Kulyk, L., D. Beshley, S. Lishchenko, V. Petsentii, A. Schnaidruk, and S. Vyshynska. "A New Morphological Variant of Acute Aortic Dissection, Non-A-Non-B Type: Choosing Treatment Strategy." Ukrainian journal of cardiovascular surgery, no. 4 (41) (December 16, 2020): 56–62. http://dx.doi.org/10.30702//ujcvs/20.4112/033056-062/089.

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Treatment of acute aortic dissection is determined by the Stanford classification which classifies all cases as type A requiring emergency surgery, and type B managed with antihypertensive therapy, and, more recently, endovascular aneurysm repair. Owing to the introduction of computed tomography (CT) and magnetic resonance imaging (MRI), a new morphological type of the disease has been identified, in which the dissection starts from the aortic arch or the first part of the descending thoracic aorta and spreads retrogradely. A new classification of acute aortic dissection – TEM (T – type, E – e

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21

Sich, Yu P., and E. P. Fisenko. "Comparative analysis of TI-RADS modifications." Medical Visualization, no. 5 (October 28, 2018): 14–20. http://dx.doi.org/10.24835/1607-0763-2018-5-14-20.

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There is no single classification of TI-RADS. In different countries, various modifications are used. It is necessary to compare different versions of the classification for choosing the most optimal variant.Objective: a comparative “blind” assessment of the thyroid nodules identified by ultrasound, according to the TI-RADS scale in various modifications.Materials and methods. Retrospective analysis of 153 echograms of thyroid lesions: colloid goiter/nodular colloid goiter – 77 observations, autoimmune thyroiditis – 11, follicular adenoma – 77, follicular cancer – 2, medullar cancer – 1, papil

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V. Telegin, I., I. M. Volodin, and P. I. Zolotukhin. "The mathematical modeling for assessing the effectiveness of hot forging extruded round in plan forgings on crank presses." International Journal of Engineering & Technology 7, no. 2.2 (2018): 30. http://dx.doi.org/10.14419/ijet.v7i2.2.9896.

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The article presents the results of the development of a mathematical model for calculating the efficiency indices of technological schemes for hot volumetric stamping (GOSH) on crank hot-stamping presses (KGSHP) round in the forgings plan (for gear, pulley and other similar parts). Software solutions obtained on the basis of this model allow choosing from several variants of technological schemes the most effective for using it in production or further improvement.

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XIAO, WENJUN, WEIDONG CHEN, and BEHROOZ PARHAMI. "Interconnection Networks with Hypercubic Skeletons." Journal of Interconnection Networks 15, no. 01n02 (2015): 1550006. http://dx.doi.org/10.1142/s0219265915500061.

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The hypercubic family of interconnection networks, encompassing the hypercube and its derivatives and variants, has a wide range of applications in parallel processing. Various problems in general complex networks can be addressed by choosing a hypercubic network as a skeleton. In this paper, we provide insight into why hypercubic networks are suitable as network skeletons and discuss a mapping scheme to take advantage of the symmetry of such networks for developing efficient algorithms.

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Kowalski, Arkadiusz, and Jolanta Żak. "Selected aspects of choosing locations on "last miles" points in the supply chain." WUT Journal of Transportation Engineering 123 (December 1, 2018): 63–73. http://dx.doi.org/10.5604/01.3001.0013.7462.

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One of the methods used to provide an immediate delivery service is to engage the final recipient in a part of the distribution process, which significantly affects the supply chain. Currently, the customer decides where and when he will want to pick up the package with the goods. In order to above, the concept of "last mile" facilities appeared. The article describes the concept of "last mile", including "last mile" facilities. These facilities include elements of the distribution system enabling direct collection or parcel delivery by the customer. The article presents the problems of locati

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Weigel, M. Margaret, and Ronald M. Weigel. "Directive use in a migrant agricultural community: A test of Ervin-Tripp's hypotheses." Language in Society 14, no. 1 (1985): 63–79. http://dx.doi.org/10.1017/s0047404500010940.

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ABSTRACTThe choice of English directive variants has been hypothesized by ErvinTripp (1976, 1977) to be determined by several social and ecological factors: the relative social ranks of the speaker and recipient, their ages, their familiarity, the presence or absence of outsiders, territorial location, and task expectations. The major goal of this investigation is to test ErvinTripp's hypotheses concerning the relationship between these variables and the choice of the identified syntactically based directive variants (imperatives, imbedded imperatives, need statements), using a distinctly diff

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Makarets, Iuliia. "Variation in the official female onomasticon of Ukraine: between norm and abnormality." Culture of the Word, no. 93 (2020): 183–95. http://dx.doi.org/10.37919/2221-8807-2017-4-14.

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The article deals with sociolinguistic analysis of modern official female onomasticon of Ukraine. Its dynamics reflects processes, which are taking place in language system, and changes in society, social demographic and ethnic pattern, cultural markers and values, even the extent of legal regulation of social relations. Sociologists are interested in personal names as a means of social categorization and differentiation of individuals. Legists see them as a tool for one’s legalization and as an object of legal protection. Anthropologists study them as special units of communication and intera

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Brena, Ramon F., Antonio A. Aguileta, Luis A. Trejo, Erik Molino-Minero-Re, and Oscar Mayora. "Choosing the Best Sensor Fusion Method: A Machine-Learning Approach." Sensors 20, no. 8 (2020): 2350. http://dx.doi.org/10.3390/s20082350.

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Multi-sensor fusion refers to methods used for combining information coming from several sensors (in some cases, different ones) with the aim to make one sensor compensate for the weaknesses of others or to improve the overall accuracy or the reliability of a decision-making process. Indeed, this area has made progress, and the combined use of several sensors has been so successful that many authors proposed variants of fusion methods, to the point that it is now hard to tell which of them is the best for a given set of sensors and a given application context. To address the issue of choosing

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Wu, Anhua, Joseph M. Zabramski, Pakrit Jittapiromsak, Robert C. Wallace, Robert F. Spetzler, and Mark C. Preul. "Quantitative Analysis of Variants of the Far-Lateral Approach." Operative Neurosurgery 66, suppl_2 (2010): ons191—ons198. http://dx.doi.org/10.1227/01.neu.0000369704.49958.5b.

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Abstract BACKGROUND The rationale for choosing between the condylar fossa and transcondylar variations of the far-lateral approach requires understanding of the relationships between the occipital condyle, jugular tubercle, and hypoglossal canal. OBJECTIVE We examined the anatomic relationship of these 3 structures and analyzed the effect that changes in these relationships have on the surgical exposure and angle of attack for these 2 approaches. METHODS Anatomic measurements of 5 cadaveric heads from 3-dimensional computed tomographic scans were compared with direct measurements of the same s

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Шевченко, Михайло Анатолійович. "Вибір складу, параметрів робочого процесу і режиму роботи силової установки літального апарата з надзвуковою крейсерською швидкістю польоту". Aerospace technic and technology, № 3 (27 травня 2021): 32–41. http://dx.doi.org/10.32620/aktt.2021.3.04.

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The issues of choosing a composition, operating process parameters and operating modes of propulsion for supersonic cruising aircraft providing transoceanic flights are considered. A condition of maximum payload relative mass is used as a criterion for choosing the composition of the propulsion. This criterion can be transformed using the aircraft mass balance equation into a condition of the minimum relative mass of fuel and propulsion. A predictor-corrector method is used to solve the task. Choosing the composition, operating process parameters and operating modes of propulsion according to

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Makarenko, Sergei I. "THE GAME MODEL OF INFORMATION CONFLICT BETWEEN THE COMMUNICATIONS SYSTEM AND THE SYSTEM OF DESTABILIZING EFFECTS." Автоматизация Процессов Управления 62, no. 4 (2020): 61–74. http://dx.doi.org/10.35752/1991-2927-2020-4-62-61-74.

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The article proposes a model of information conflict between the application specific communications system and the system of destabilizing effects based on the game theory formalism. The model takes into account strategies of destabilizing effects and of communications system protection, as well as their change during the information conflict. It shows that based on the game with direct or mixed strategies, it is possible to substantiate the most probably variants of destabilizing effects, as well as the rational structure of communications system in the conflict. The authors propose decision

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Billings, John, Theo Georghiou, Ian Blunt, and Martin Bardsley. "Choosing a model to predict hospital admission: an observational study of new variants of predictive models for case finding." BMJ Open 3, no. 8 (2013): e003352. http://dx.doi.org/10.1136/bmjopen-2013-003352.

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Pozdnyakov, N. O., I. N. Kagarmanyan, A. E. Miroshnikov, et al. "Pharmacogenetic Aspects of Type 2 Diabetes Treatment." Acta Biomedica Scientifica 5, no. 3 (2020): 13–23. http://dx.doi.org/10.29413/abs.2020-5.3.2.

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In this article, we analyze the role of different variants of the KCNJ11, TCF7L2, SLC22A1, SLC22A3, CYP2C9, CYP2C8, PPARγ genes polymorphisms in efficacy of diabetes mellitus pharmacotherapy. T allele of the KCNJ11 rs2285676 gene polymorphism and G allele of KCNJ11 rs5218 gene polymorphism are associated with the response to IDPP-4 therapy; the presence of KCNJ11 gene rs5210 polymorphism A allele is a predictor of poor response. The effect of rs7903146 polymorphism of TCF7L2 gene was evaluated on the response to treatment of patients taking linagliptin. Linagliptin significantly reduced HbA1c

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Епихин, А. И., Е. В. Хекерт, and М. А. Модина. "Principles of neural control and variants of neural network architecture, applied to a complex dynamic system of sea-vessel." MORSKIE INTELLEKTUAL`NYE TEHNOLOGII), no. 4(50) (December 17, 2020): 18–22. http://dx.doi.org/10.37220/mit.2020.50.4.091.

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В статье рассматриваются возможности, особенности и перспективы внедрения принципов нейроуправления в контур регулирования, контроля и эксплуатации сложной динамической системы СЭУ-СУДНО. Отдельное внимание уделено базовым характеристикам и принципам нейроуправления. Рассмотрена структурная схема и принцип проектирования нейрорегулятора применительно к данной системе. Кроме того, формализована процедура настройки нейронной сети на моделирование входа/выхода объекта управления, а также принцип выбора архитектуры, определения критериев оптимизации нейронной сети для управления СЭУ-СУДНО. Рассмот

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Hayati, Maryam, Priscila Biller, and Caroline Colijn. "Predicting the short-term success of human influenza virus variants with machine learning." Proceedings of the Royal Society B: Biological Sciences 287, no. 1924 (2020): 20200319. http://dx.doi.org/10.1098/rspb.2020.0319.

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Seasonal influenza viruses are constantly changing and produce a different set of circulating strains each season. Small genetic changes can accumulate over time and result in antigenically different viruses; this may prevent the body’s immune system from recognizing those viruses. Due to rapid mutations, in particular, in the haemagglutinin (HA) gene, seasonal influenza vaccines must be updated frequently. This requires choosing strains to include in the updates to maximize the vaccines’ benefits, according to estimates of which strains will be circulating in upcoming seasons. This is a chall

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Kravets, L. Ya, and A. D. Pogosyan. "Non-saccular aneurysms: pathogenesis, clinic and methods of treatment (review)." Russian journal of neurosurgery 22, no. 3 (2020): 76–83. http://dx.doi.org/10.17650/1683-3295-2020-22-3-76-83.

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In clinical practice, we use the term “fusiform aneurysm” for local expansion of artery. Under this generic term specialists understand heterogeneous arterial pathology, which is very important for diagnosis and choosing the treatment. We conducted an analysis of scientific literature published in 1987–2019, including 63 foreign and 4 Russian sources devoted to pathogenesis and types of non-saccular aneurysms. Among non-saccular aneurysms, dolichoectatic aneurysms are distinguished, rather of genetically or non-atherosclerotic origin and fusiform aneurysm acquired due to dissection processes.

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Radtsig, E. Yu. "New possibilities of elimination-irrigation therapy drugs during the seasonal rise in the incidence of acute respiratory viral infections and influenza." Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 64, no. 6 (2020): 110–13. http://dx.doi.org/10.21508/1027-4065-2019-64-6-110-113.

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Various methods and variants of nasal cavity irrigation are one of the most ancient in the treatment and prevention of diseases of the upper respiratory tract. When choosing a remedy for elimination and irrigation therapy, preference is given to preparations based on sea water, containing in its composition minerals and trace elements that cause additional therapeutic effect. A new direction in this type of therapy is the use of drugs containing fucoidans (obtained from brown algae extract). Their immunostimulatory and anti-inflammatory effect can improve the effectiveness of elimination and i

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Rogozhina, Yulia, Svetlana Blohina, and Evgeniya Bimbas. "SURGICAL TACTICS FOR ELIMINATING COMPLEX VARIANTS OF CONGENITAL CLEFT PALATE." Actual problems in dentistry 16, no. 1 (2020): 121–26. http://dx.doi.org/10.18481/2077-7566-20-16-1-121-126.

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Subject. Surgical methods for eliminating congenital clefts of the upper lip and palate are widely presented in the specialized literature and correspond to the variety of types of lesions of the maxillofacial region. At the same time, international and domestic experience, research results on these issues emphasize the need for continuous improvement of surgical and rehabilitation techniques to eliminate them. In most cases, the use of these developments follows the path of detailing and updating existing classical technologies. Purpose ― to present a surgical method for removal of a co

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Andres, Oliver, Eva-Maria König, Karina Althaus, et al. "Use of Targeted High-Throughput Sequencing for Genetic Classification of Patients with Bleeding Diathesis and Suspected Platelet Disorder." TH Open 02, no. 04 (2018): e445-e454. http://dx.doi.org/10.1055/s-0038-1676813.

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AbstractInherited platelet disorders (IPD) form a rare and heterogeneous disease entity that is present in about 8% of patients with non-acquired bleeding diathesis. Identification of the defective cellular pathway is an important criterion for stratifying the patient's individual risk profile and for choosing personalized therapeutic options. While costs of high-throughput sequencing technologies have rapidly declined over the last decade, molecular genetic diagnosis of bleeding and platelet disorders is getting more and more suitable within the diagnostic algorithms. In this study, we develo

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ARAN, OYA, OLCAY TANER YILDIZ, and ETHEM ALPAYDIN. "AN INCREMENTAL FRAMEWORK BASED ON CROSS-VALIDATION FOR ESTIMATING THE ARCHITECTURE OF A MULTILAYER PERCEPTRON." International Journal of Pattern Recognition and Artificial Intelligence 23, no. 02 (2009): 159–90. http://dx.doi.org/10.1142/s0218001409007132.

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We define the problem of optimizing the architecture of a multilayer perceptron (MLP) as a state space search and propose the MOST (Multiple Operators using Statistical Tests) framework that incrementally modifies the structure and checks for improvement using cross-validation. We consider five variants that implement forward/backward search, using single/multiple operators and searching depth-first/breadth-first. On 44 classification and 30 regression datasets, we exhaustively search for the optimal and evaluate the goodness based on: (1) Order, the accuracy with respect to the optimal and (2

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Alekseychyk, Larysa, Cheng Su, Gerald W. Becker, Michael J. Treuheit, and Vladimir I. Razinkov. "High-Throughput Screening and Analysis of Charge Variants of Monoclonal Antibodies in Multiple Formulations." SLAS DISCOVERY: Advancing the Science of Drug Discovery 22, no. 8 (2017): 1044–52. http://dx.doi.org/10.1177/2472555217711666.

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Among different biopharmaceutical products, monoclonal antibodies (mAbs) show a high level of complexity, including heterogeneity due to differences in size, hydrophobicity, charge, and so forth. Such heterogeneity can be related to both cell-based production and any of the stages of purification, storage, and delivery that the mAb is subjected to. Choosing the right formulation composition providing both physical and chemical stabilities can be a very challenging process, especially when done in the limited time frame required for a typical drug development cycle. Charge variants, a common ty

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Ammirati, Mario, Antonio Bernardo, Angelo Musumeci, and Albino Bricolo. "Comparison of different infratentorial—supracerebellar approaches to the posterior and middle incisural space: a cadaveric study." Journal of Neurosurgery 97, no. 4 (2002): 922–28. http://dx.doi.org/10.3171/jns.2002.97.4.0922.

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Object. The purpose of this investigation was to describe and compare through cadaveric dissection the microsurgical exposure afforded by the median, paramedian, and extreme-lateral infratentorial—supracerebellar approaches to the posterior and middle incisural space. Methods. The median, paramedian, and extreme-lateral infratentorial—supracerebellar approaches were performed in 10 embalmed cadaveric heads by using standard microneurosurgical methods; each approach was executed a minimum of five times. The dissections were performed in a stepwise fashion, comparing the exposure afforded by eac

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Irzmańska, Emilia, and Anna Bacciarelli-Ulacha. "Effects of simulated pressure of wooden, plastic, and metal materials on the thermal insulation of cold-protective gloves of various designs." Textile Research Journal 89, no. 19-20 (2019): 4060–70. http://dx.doi.org/10.1177/0040517519829005.

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The paper proposes a new approach to selecting cold-protective gloves for workers by evaluating the effects of simulated pressure of wood, plastic, and metal materials on the thermal insulation of gloves of various designs. Thermal insulation tests involved three models of gloves offering stable thermal insulation at various temperatures. The tests were carried out on a thermal hand model according to EN 511:2006. In the study, three variants of contact surface were used: metal, plastic, and wood. It was found that the thermal insulation of protective gloves under pressure decreases and depend

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Čiegis, Remigijus, Dainora Grundey, and Dalia Štreimikiene. "ECONOMIC ASPECTS OF CITIES SUSTAINABLE DEVELOPMENT STRATEGIC PLANNING." Technological and Economic Development of Economy 11, no. 4 (2005): 260–69. http://dx.doi.org/10.3846/13928619.2005.9637706.

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In Lithuania, like in other post communistic countries, the principles of sustainable development were used only few years ago, basically only in case, that it was “in vogue” in the whole world. Strategic plans were created usually in such a way that everyone understood, not paying attention to quality and real destination. Most of investors choosing places for their investments usually analyse strategic plans and this is one of the critical factors for choosing the place for investments or at least choosing possible variants. At present Lithuanians are starting to understand the importance of

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Neroeva, N. V., V. V. Neroev, M. V. Ryabina, A. G. Karmokova, and O. A. Losanova. "Mixed (combined) phenotype of the late stage of age-related macular degeneration." Russian Ophthalmological Journal 14, no. 2 (2021): 69–75. http://dx.doi.org/10.21516/2072-0076-2021-14-2-69-75.

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With multimodal visualization of the chorioretinal complex structures using modern research methods, it was possible to isolatea mixed, or combined, phenotype of the late stage of age-related macular degeneration (AMD). Early detection of this AMD form is of vital importance not only for accurate diagnosis, but for choosing optimal management tactics for patients. The paper presents two clinical cases with different variants of the development of the mixed phenotype of the late AMD stage. In one case, the long-lasting “geographic atrophy” (GA) was complicated by the development of choroidal ne

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Brodetskyi, Igor S., Olena O. Dyadyk, Mykhailo S. Myroshnychenko, and Valentina I. Zaritska. "MORPHOLOGICAL CHARACTERISTICS OF PLEOMORPHIC ADENOMAS OF SALIVARY GLANDS (ANALYSIS OF THE SURGICAL MATERIAL)." Wiadomości Lekarskie 73, no. 11 (2020): 2339–44. http://dx.doi.org/10.36740/wlek202011103.

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The aim of the study is to reveal the morphological features of pleomorphic adenomas of the salivary glands during a comprehensive examination of the surgical material. Materials and methods: Surgical material from 30 patients with pleomorphic adenomas of the salivary glands was studied. Microspecimens stained with hematoxylin and eosin were studied, using an Olympus BX-41 microscope (Japan) with subsequent processing with the Olympus DP-soft version 3.1 software, which was used to conduct a morphometric study. By morphometry in the tumor tissue, the specific volumes of the parenchyma and stro

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Arnaout, Ramy, Thomas P. Buck, Paulvalery Roulette, and Vikas P. Sukhatme. "Predicting the Cost and Pace of Pharmacogenomic Advances: An Evidence-Based Study." Clinical Chemistry 59, no. 4 (2013): 649–57. http://dx.doi.org/10.1373/clinchem.2012.199455.

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BACKGROUND Adverse outcomes associated with prescription drug use are common and costly. Many adverse outcomes can be avoided through pharmacogenomics: choosing and dosing of existing drugs according to a person's genomic variants. Finding and validating associations between outcomes and genomic variants and developing guidelines for avoiding drug-related adverse outcomes will require further research; however, no data-driven estimates yet exist for the time or money required for completing this research. METHODS We identified examples of associations between adverse outcomes and genomic varia

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Цимбалюк, Ж. О., Л. В. Коник, and В. А. Тихонова. "Algorithm for Assessment of Students’ Individual Choice of Sports Sections." Teorìâ ta Metodika Fìzičnogo Vihovannâ, no. 2 (August 6, 2016): 21–26. http://dx.doi.org/10.17309/tmfv.2016.2.1160.

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Research objective. To develop a model of students’ decision-making when individually choosing a sports section. Research methods: The study relies on the analysis of scientific and methodological literature, questionnaires, and factor analysis. The participants in the study were 55 first-year students (2015 enrollment year) of the School of Ukrainian Language and Literature of H.S. Skovoroda Kharkiv National Pedagogical University. Research results. The analysis of the questionnaires showed diverse motivational choices. The factor analysis revealed the prevailing motifs. The study comes up wi

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Hatipoğlu, Tevfik, Esra Esmeray, Xiaozhou Hu, et al. "Ultra-Deep Targeted Sequencing Reveals Cancer-Associated, Prognostically Significant Mutations in Circulating Cell-Free DNA in Treatment-Naive Patients with Follicular Lymphoma." Blood 136, Supplement 1 (2020): 20–21. http://dx.doi.org/10.1182/blood-2020-136281.

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Background: Follicular lymphoma is the second most frequent non-Hodgkin lymphoma (NHL) accounting for 20-25% of NHL cases in western countries. Although it has an indolent character, progressive disease or relapse occurs within first two years following therapy initiation in ~20% of FL cases. Several somatic mutations were identified in genes of epigenetic regulation or other biological processes by sequencing of FL tumors. Current diagnostic and prognostic evaluations include invasive methodologies that may be less effective and more risky for the FL patients. Therefore, there is urgent need

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Overgaard, Nana H., Timothy M. Fan, Kyle M. Schachtschneider, Daniel R. Principe, Lawrence B. Schook, and Gregers Jungersen. "Of Mice, Dogs, Pigs, and Men: Choosing the Appropriate Model for Immuno-Oncology Research." ILAR Journal 59, no. 3 (2018): 247–62. http://dx.doi.org/10.1093/ilar/ily014.

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Abstract The immune system plays dual roles in response to cancer. The host immune system protects against tumor formation via immunosurveillance; however, recognition of the tumor by immune cells also induces sculpting mechanisms leading to a Darwinian selection of tumor cell variants with reduced immunogenicity. Cancer immunoediting is the concept used to describe the complex interplay between tumor cells and the immune system. This concept, commonly referred to as the three E’s, is encompassed by 3 distinct phases of elimination, equilibrium, and escape. Despite impressive results in the cl

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Glushkov, Nikolay I., Michael A. Ivanov, Petr D. Puzdryak, Kristina V. Samko, Alina A. Isakova, and Anastasia S. Artemova. "Metabolic disorder and outcomes of reconstructive interventions in patients with peripheral arterial disease." HERALD of North-Western State Medical University named after I.I. Mechnikov 11, no. 3 (2019): 33–40. http://dx.doi.org/10.17816/mechnikov201911333-40.

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The purpose of this study was to assess the effect of metabolic disorders on the effects of revascularization in patients with obliterating atherosclerosis. Materials and methods. The reconstruction was performed in 253 patients with femoral-tibial arterial segment lesion (98 open operations, 116 endovascular interventions and 39 patients were treated with hybrid technique). Results. Endovascular revascularization techniques are justified in case of disorders of carbohydrate metabolism. Conventional operations remain the method of choice in the case of those variants of atheroscler

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