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Journal articles on the topic 'CHR 1597'

Author: Grafiati

Published: 28 July 2024

Last updated: 31 July 2025

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1

Park, Hyun Kyu. "Research on the Jinglue Yuwo zhouyi(經略御倭奏議) of Xing jie(邢玠) during the Japan’s Second Invasion of Korea in 1597-1598(丁酉再亂)". CHUNGGUKSA YONGU (The Journal of Chinese Historical Researches) 113 (30 квітня 2018): 35–62. http://dx.doi.org/10.24161/chr.113.35.

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Giani, Marco. "Donna, che fosti tra le donne un Sole»: sui tentativi poetici giovanili di Paolo Paruta (metà XVI sec.)." Italianistica Debreceniensis 23 (December 1, 2017): 60–73. http://dx.doi.org/10.34102/italdeb/2017/4638.

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During the mid-1560s, Paolo Paruta (1540-1598), future Ambassador of the Republic of Venice in Rome (1591-1595) and author of the three books of Perfettione della Vita Politica (Venice, 1579) wrote some poems: the canzone Donna, che fosti tra le donne un Sole, and three somnets. The former was then published in Dionigi Atanagi’s Rime di diversi nobilissimi et eccellentissimi autori, in morte della Signora Irene delle Signore di Spilimbergo (Venice, 1561), the latters were insert in Diomede Borghesi’s anthology for Cinzia Braccioduro Garzadori (then published in Padua, 1567, without Paruta’s so

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Peltier, Cyril. "Le passage présumé du sculpteur bourguignon Juan de Juni (1507-1577) en Occitanie." Annales de Bourgogne Tome 95, no. 3 (2024): 59–80. http://dx.doi.org/10.3917/anbo.233.0059.

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Comme de nombreux compatriotes, le sculpteur d’origine bourguignonne Jean de Joigny (1507-1577) s’installa en Espagne au début du Siècle d’Or, attiré par les possibilités de travail et d’enrichissement. Devenu Juan de Juni, il réalisa au total une cinquantaine d’œuvres, principalement en bois polychrome, consacrées à la Passion du Christ et au culte marial. Aussi, de par son intense activité ibérique Juan de Juni est considéré comme un artiste espagnol à part entière. Mais faut-il restreindre son œuvre à la sphère artistique ibérique ? Précisément, notre étude vise à faire la lumière sur son p

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4

Peltier, Cyril. "Le passage présumé du sculpteur bourguignon Juan de Juni (1507-1577) en Occitanie." Annales de Bourgogne Tome 96, no. 1 (2024): 59–80. http://dx.doi.org/10.3917/anbo.241.0059.

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Comme de nombreux compatriotes, le sculpteur d’origine bourguignonne Jean de Joigny (1507-1577) s’installa en Espagne au début du Siècle d’Or, attiré par les possibilités de travail et d’enrichissement. Devenu Juan de Juni, il réalisa au total une cinquantaine d’œuvres, principalement en bois polychrome, consacrées à la Passion du Christ et au culte marial. Aussi, de par son intense activité ibérique Juan de Juni est considéré comme un artiste espagnol à part entière. Mais faut-il restreindre son œuvre à la sphère artistique ibérique ? Précisément, notre étude vise à faire la lumière sur son p

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5

Nguyen Dinh, Hung, Thuy Luong Thi Thu, and Khu Le Van. "Study on the preparation and electrochemical performance of nickel sulfide for the application in an electrochemical capacitor." Journal of Science Natural Science 68, no. 1 (2023): 43–52. http://dx.doi.org/10.18173/2354-1059.2023-0004.

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NiS as an electrode material for electrochemical capacitors has been synthesized by chemical and hydrothermal methods. The results show that the synthesized NiS is in amorphous form, increasing the reaction temperature or hydrothermal time tends to reduce the porosity of the materials. NiS synthesized by hydrothermal method exhibits better electrochemical properties than those synthesized by chemical method. NiS synthesized at the optimal condition of a hydrothermal temperature of 140 oC in 5h has a specific capacitance of 1592 F\g (265 mAh\g) and 1567 F\g (261 mAh\g) at a scan rate of 5 mV\s

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6

Liu, An Qi. "Inspectting of the Bureaucracy of Ming Dynasty through Jocheonlog(朝天錄) During ImJin War(1592-1598)". CHUNGGUKSA YONGU (The Journal of Chinese Historical Researches) 128 (31 жовтня 2020): 85–106. http://dx.doi.org/10.24161/chr.128.85.

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7

Hedman, Dag. "Io che quasi pastor tra questi boschi." Tidskrift för litteraturvetenskap 42, no. 2-3 (2012): 111–23. http://dx.doi.org/10.54797/tfl.v42i2-3.11689.

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Io che quasi pastor tra questi boschi. A Discussion of Two favola in musica-Prologues by Ottavio Rinuccini The essay deals with the famous Florentine author and courtier Ottavio Rinuccini (1562–1621), more specifically with his librettos. Following an outline of Rinuccini’s career as a dramatist in the period 1579–1621, the prologues to his successful La rappresentazione di Dafne (1594/95) and his never performed Il Narciso (1608) are discussed. In both, Rinuccini departs from the standard procedure of having an allegorical or mythological person perform the prologue. Instead, he employs

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8

Li, Jing Fang. "[Rook Review] Lin Yu-feng, The Beginning of the Modern Chinese Press History: Macao Press History 1557-1840." CHUNGGUKSA YONGU (The Journal of Chinese Historical Researches) 111 (December 31, 2017): 267–71. http://dx.doi.org/10.24161/chr.111.267.

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9

Colucci, Eduardo, Simone Dal Corso, Jaqueline Paula Borges, Luiz Eduardo Nery, and Carla Malaguti. "CRITICAL VS ESTIMATED HEART RATE IN ELDERLY SUBJECTS." Revista Brasileira de Medicina do Esporte 26, no. 2 (2020): 134–38. http://dx.doi.org/10.1590/1517-869220202602195867.

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ABSTRACT Introduction: Heart rate (HR) has been a simple and easy-to-use physiological parameter widely used to determine exercise intensity. The critical power fatigue limit model, known as the critical heart rate (CHR), can be extrapolated to HR. However, an estimate for a CHR mathematical model has not yet been extrapolated for upper limb exercise in the elderly. Objective: To compare the mathematical model previously used to estimate CHR with the heart rate values at the critical power (CP) during arm-ergometer exercises in elderly subjects. Methods: After an initial maximum-incremental ex

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10

Labrèche, Yves. "Paul Lejeune (1591–1664), missionnaire de Nouvelle-France, le premier linguiste et grammairien de l’innu." Canadian Historical Review 100, no. 1 (2019): 110–12. http://dx.doi.org/10.3138/chr.100.1.br07.

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11

Salin, Dominique. "Pierre Emonet, PIERRE CANISIUS L’infatigable réformateur de l’Église d’Allemagne (1521-1597) Lessius, « Petite bibliothèque jésuite », 2020, 192 p., 14 €." Christus 269, no. 1 (2021): 122–23. https://doi.org/10.3917/chri.269.0124.

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12

Aaron, Melissa D. "Shakespeare's Opposites: The Admiral's Company, 1594–1625 (review)." Comparative Drama 45, no. 2 (2011): 145–47. http://dx.doi.org/10.1353/cdr.2011.0009.

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13

Uytven, R. van. "C.R. Steen, A chronicle of conflict: Tournai, 1559-1567." BMGN - Low Countries Historical Review 102, no. 4 (1987): 648. http://dx.doi.org/10.18352/bmgn-lchr.2869.

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14

Highley, Christopher. "Living with Shakespeare: Saint Helen's Parish, London, 1593-1598 by Geoffrey Marsh." Comparative Drama 56, no. 4 (2022): 422–23. http://dx.doi.org/10.1353/cdr.2022.0027.

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15

Sheen, Joo Hyun. "Yang Tingyun's Acceptance of Catholicism and his Initiation of Buru yifo in Late Ming China." CHUNGGUKSA YONGU (The Journal of Chinese Historical Researches) 125 (April 30, 2020): 233–63. http://dx.doi.org/10.24161/chr.125.233.

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16

Jensen, Ejner J. "The Profession of Player in Shakespeare’s Time, 1590–1642 by Gerald Eades Bentley." Comparative Drama 19, no. 4 (1985): 363–65. http://dx.doi.org/10.1353/cdr.1985.0039.

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17

Kirwan, Peter. "Europe's Languages on England's Stages, 1590-1620 by Marianne Montgomery (review)." Comparative Drama 47, no. 1 (2013): 138–41. http://dx.doi.org/10.1353/cdr.2013.0014.

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18

Husak, Y. V., O. A. Holichenko, V. V. Zakatov, and A. V. Shtemenko. "Interaction of trans-tetrachlorodi-m-carboxylates of dirhenium(III) with dipeptides of the glycyl series." Voprosy Khimii i Khimicheskoi Tekhnologii, no. 3 (June 2022): 21–25. http://dx.doi.org/10.32434/0321-4095-2022-142-3-21-25.

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The paper reports the methods for the synthesis of new cluster compounds of trans-tetrachlorodi--carboxylates of dirhenium(III) with dipeptides of the glycyl series. The compositions and the structures were determined by electron absorption and IR spectroscopies as well as by elemental analysis for the following newly synthesized compounds: trans-[Re2(H3N+–CH2–СO–NH–CH(COO)–CH2–CH(CH3)–CH3)2Cl42СН3CN]Cl2 (І) and trans-[Re2(H3N+–CH2–СO–NH–CH(COO)–CH2–C6H5)2Cl42СН3CN]Cl2 (ІІ). Analysis of the electronic absorption spectra of the solutions of the synthesized substances showed the presence of a

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19

McLachlan, Sandra M., Holly A. Aliesky, Pavel N. Pichurin, Chun-Rong Chen, Robert W. Williams, and Basil Rapoport. "Shared and Unique Susceptibility Genes in a Mouse Model of Graves’ Disease Determined in BXH and CXB Recombinant Inbred Mice." Endocrinology 149, no. 4 (2007): 2001–9. http://dx.doi.org/10.1210/en.2007-1517.

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Susceptibility genes for TSH receptor (TSHR) antibodies and hyperthyroidism can be probed in recombinant inbred (RI) mice immunized with adenovirus expressing the TSHR A-subunit. The RI set of CXB strains, derived from susceptible BALB/c and resistant C57BL/6 (B6) mice, were studied previously. High-resolution genetic maps are also available for RI BXH strains, derived from B6 and C3H/He parents. We found that C3H/He mice develop TSHR antibodies, and some animals become hyperthyroid after A-subunit immunization. In contrast, the responses of the F1 progeny of C3H/He × B6 mice, as well as most

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20

Westfall, Suzanne. "The Boy Who Would Be King: Court Revels of King Edward VI, 1547-1553." Comparative Drama 35, no. 3-4 (2001): 271–90. http://dx.doi.org/10.1353/cdr.2001.0002.

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21

Sarrazin, Sophie. "Le traitement de la forme en -ría dans la Grammaire et observations de la langue espagnolle recueillies & mises en françois de César Oudin (1597)." Recherches, no. 14 (June 1, 2015): 129–52. http://dx.doi.org/10.4000/cher.5030.

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22

Shapiro, Michael. "Gentlemen of a Company: English Players in Central and Eastern Europe, 1590-1660 by Jerzy Limon." Comparative Drama 21, no. 1 (1987): 93–94. http://dx.doi.org/10.1353/cdr.1987.0017.

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23

Bernier, Jacques. "Jacques Cartier, les merveilles du Nouveau Monde et l’annedda." Canadian Historical Review 105, no. 2 (2024): 257–75. http://dx.doi.org/10.3138/chr-2022-0027.

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Jacques Cartier (1491-1557) reports, in the account of his second voyage to Canada in 1535-1536, that his crew was afflicted with a “grosse maladie” (scurvy) as well as other diseases, including a case of “grosse verolle” (syphilis), but was cured thanks to herbal teas made with the leaves of a tree called annedda, and in only six days. Until now, research on the annedda episode in the récit du deuxième voyage de Cartier has focused essentially on the nature of the “grosse maladie”, on the identification of the plant called annedda, as well as its potential therapeutic virtues. This study aims

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24

Charlotte Le Bailly, Marie. "Synopsis Praxeos Civilis, manier van procederen in dese provintiën, Hollandt, Zeelandt ende West-Vrieslandt, belanghende civile saken – 1592." Pro Memorie 21, no. 2 (2019): 34–37. http://dx.doi.org/10.5117/pm2019.2.006.char.

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25

Takada, Mamoru, Sakuntha Gunarathna, Hideyuki Yamada, et al. "Abstract P5-02-23: Unveiling the Antitumor Mechanism of abemaciclib in Human Breast Cancer Through Circulating Tumor Chromatin Analysis." Clinical Cancer Research 31, no. 12_Supplement (2025): P5–02–23—P5–02–23. https://doi.org/10.1158/1557-3265.sabcs24-p5-02-23.

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Abstract Background: The study of circulating tumor DNA (ctDNA) and cell-free chromatin (cf-Chr) has become instrumental in advancing our understanding of cancer biology. This research delves into the antitumor mechanism of abemaciclib in ER-positive, HER2-negative metastatic breast cancer patients by examining cf-Chr fragmentation patterns. Methods: In this investigation, 72 ER-positive, HER2-negative metastatic breast cancer patients, as defined by ASCO/CAP guidelines and treated with abemaciclib at Chiba University Hospital in Japan from 2020 to 2022, were enrolled. Pre- and post-treatment

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26

Metesi Deronjić, Željka. "Il poeta che visse due volte Sulle ragioni di una polemica letteraria tra Frane Petrić e Iacopo Mazzoni*." Prilozi za istraživanje hrvatske filozofske baštine 49, no. 2 (98) (2023): 213–26. http://dx.doi.org/10.52685/pihfb.49.2(98).1.

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Un anno dopo la pubblicazione dei primi due volumi della Poetica (Ferrara, 1586) di Frane Petrić (Francesco Patrizi da Cherso), intitolati Deca istoriale e Deca disputata, Iacopo Mazzoni pubblica la prima parte della sua voluminosa opera intitolata Della difesa della Comedia di Dante. Distinta in sette libri (Cesena, 1587). Qui, nel ventesimo capitolo del terzo libro, Mazzoni fa alcune osservazioni critiche su quanto scritto da Petrić nella Deca istoriale a proposito di Sositeo, un poeta tragico greco della Pleiade (III secolo a.C.), entrando così in polemica con il filosofo di Cherso. Oggi, q

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27

Zhang, Zhen. "TAI CHI IMPACTS ON NEUROMUSCULAR FUNCTIONS IN THE LOWER LIMBS OF THE ELDERLY." Revista Brasileira de Medicina do Esporte 28, no. 5 (2022): 581–83. http://dx.doi.org/10.1590/1517-8692202228052022_0015.

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ABSTRACT Introduction: Exercise can retard the effects of aging and improve the physical function of the elderly. Tai Chi is a widespread exercise practice among the elderly in China. Although studies show the positive effects of Tai Chi practice, there is no consensus about compared studies. Objective: Evaluate the impact of regular Tai Chi exercise on neuromuscular stability in the lower limbs of elderly people, comparing the results of practitioners between sedentary and walking elderly groups. Methods: Twenty-two Tai Chi practitioners were selected, with a mean age of 59.3±3.5 years and a

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Garcia, Ernest. "Car le temps est proche : la crise écologique et l’apocalypse sans cesse annoncée." Socio-anthropologie, no. 28 (December 15, 2013): 117–31. http://dx.doi.org/10.4000/socio-anthropologie.1597.

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Towse, Adrian, Martina Garau, Penny Mohr, and Donna A. Messner. "Futurescapes: expectations in Europe for relative effectiveness evidence for drugs in 2020." Journal of Comparative Effectiveness Research 4, no. 4 (2015): 401–18. http://dx.doi.org/10.2217/cer.15.7.

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30

Silver, Marc A. "CME in CHF." Congestive Heart Failure 9, no. 3 (2003): 125. http://dx.doi.org/10.1111/j.1527-5299.2003.02572.x.

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31

Ke, Wanli. "RESPONSES OF TAI CHI IN UPPER LIMB SPORTS INJURIES REHABILITATION ON YOUNG PEOPLE." Revista Brasileira de Medicina do Esporte 28, no. 6 (2022): 814–16. http://dx.doi.org/10.1590/1517-8692202228062022_0018.

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ABSTRACT Introduction Practicing sports can strengthen the body both physically and mentally. Although Tai Chi can help injured athletes to recover quickly and shorten the return to sports training and competition, there are still no detailed studies about its effectiveness in lower limb injuries in young people. Objective Analyze the effects of Tai Chi in upper limb sports injuries rehabilitation on young people. Methods 91 patients with sports injuries are selected and randomly divided into a control group (n=44) and an experimental group (n=47). The control group received regular exercises

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Hameed, Saba, Xia Li, Yunyi Zhou, et al. "Genome-Wide Dissection of MATE Gene Family in Cultivated Peanuts and Unveiling Their Expression Profiles Under Aluminum Stress." International Journal of Molecular Sciences 26, no. 6 (2025): 2707. https://doi.org/10.3390/ijms26062707.

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Peanut faces yield constraints due to aluminum (Al) toxicity in acidic soils. The multidrug and toxic compound extrusion (MATE) family is known for extruding organic compounds and transporting plant hormones and secondary metabolites. However, the MATE transporter family has not yet been reported in peanuts under the Al stress condition. In this genome-wide study, we identified 111 genes encoding MATE proteins from the cultivated peanut genome via structural analysis, designated as AhMATE1–AhMATE111. Encoded proteins ranged from 258 to 582 aa residues. Based on their phylogenetic relationship

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33

Taylor, Dennis. "Texts and Traditions: Religion in Shakespeare 1592–1604, and: Shakespeare's Christianity: The Protestant and Catholic Poetics of Julius Caesar, Macbeth, and Hamlet (review)." Comparative Drama 41, no. 3 (2007): 397–401. http://dx.doi.org/10.1353/cdr.2007.0038.

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34

Солдатова, Л. И., Ю. И. Шмидт, and И. В. Жуплей. "Assessment of implementation of the project of car wash." Экономика и предпринимательство, no. 11(124) (December 23, 2020): 719–24. http://dx.doi.org/10.34925/eip.2020.124.11.140.

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Профессионально оборудованная и управляемая автомойка представляет собой одну из наиболее привлекательных инвестиций, доступных в современной экономике. В одном из районных центров Костромской области для обслуживания легковых автомобилей работают две автомойки, которые не предоставляют услуги по мойке внедорожников, микроавтобусов и грузового транспорта. При реализации проекта с предоставление автомоечных услуг для всех видов транспорта общая потребность в финансировании по проекту составит 508033,4 рублей. Источниками финансирования являются собственные средства предприятия. С внедрением про

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Yang, Seongmin, Seungyeob Han, Yeo-Myeong Yun, and Seoktae Kang. "Stimulation of Biomethane Productivity in Anaerobic Digestion Using Electro-Conductive Carbon-Nanotube Hollow-Fiber Media." Minerals 11, no. 2 (2021): 179. http://dx.doi.org/10.3390/min11020179.

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The production of biogas was promoted via direct interspecies electron transfer (DIET) by employing electro-conductive carbon-nanotube hollow-fiber media (CHM) in anaerobic digestion. Experimental results showed a positive effect of CHM presence on CH4 productivity with 34% higher CH4 production rate than that of in the presence of non-electroconductive polymeric hollow fiber media. An increased CH4 production rate was due to the shift in the microbiome with more abundant Pelobacter (10.0%), Geobacter (6.9%), and Methanosaeta (15.7%), which play key roles in promoting CH4 production via syntro

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Villalobos, Aremis, Claudia Unikel, Maria I. Hernández-Serrato, and Ietza Bojorquez. "Evolución de las conductas alimentarias de riesgo en adolescentes mexicanos, 2006-2018." Salud Pública de México 62, no. 6, Nov-Dic (2020): 734–44. http://dx.doi.org/10.21149/11545.

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Objetivo. Analizar la evolución de la prevalencia de conductasalimentarias de riesgo (CAR) en adolescentes mexicanosentre 2006 y 2018. Material y métodos. Se utilizóinformación de las Ensanut 2006 y 2018-19. Se evaluaron lasCAR con el Cuestionario Breve de Conductas Alimentariasde Riesgo, distinguiendo entre normativas (recomendadasen la prevención de la obesidad) y no normativas (no recomendadas).Se analizó la relación entre CAR e indicadoresdel medio ambiente sociocultural en que los adolescentes sedesenvuelven (nivel socioeconómico, tamaño de la localidad).Resultados. La prevalencia de CAR

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37

Scanavino, Francesca. "Beneficiario che non si identifica e trustee che non gli versa nulla (Kekwick v Kekwick, 12 ottobre 2022)." N° 1 (gennaio-febbraio), no. 5 (February 1, 2024): 96–106. http://dx.doi.org/10.35948/1590-5586/2024.485.

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Tesi Non può essere considerato inadempiente il trustee che abbia deciso di non investire il fondo in trust in attività finanziarie aventi un potenziale tasso di rischio, nel caso in cui tale decisione sia stata presa sulla base di un parere legale che abbia consigliato di non fare investimenti se non con la massima prudenza (e ciò anche nel caso in cui il parere si riveli errato). Inoltre, non sorge l’obbligo di distribuzione del fondo in trust in capo al trustee allorquando quest’ultimo non possa adempiere al medesimo senza violare, o rischiare di violare, il concomitante dovere in capo al m

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Wang, Feng, and Yong Hai Wu. "Study of Regenerative Braking Model and Simulation of a Car." Advanced Materials Research 605-607 (December 2012): 384–87. http://dx.doi.org/10.4028/www.scientific.net/amr.605-607.384.

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A regenerative braking control strategy and the braking force distribution are putted forward based on the basic theory of automotive brake. The model of vehicle regenerative braking system and simulation under urban driving cycles are carried out taking a certain type of hybrid car as the research object. The simulation results show that, in circulation conditions of ECE + EUDC drive, the regenerative braking control strategy that this paper puts forward can ensure the reasonable distribution of vehicle braking force and realize the energy recovery of 15.7%.

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Weber, Karl T., Brad S. Burlew, Richard C. Davis, et al. "CHF: Circulatory Homeostasis Gone Awry." Congestive Heart Failure 8, no. 1 (2002): 37–48. http://dx.doi.org/10.1111/j.1527-5299.2002.00720.x.

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40

Maccalli, Cristina, Asma Al-Sulaiti, Mohammed El-Anbari, et al. "102 The deep phenotype characterization of ‘Off-the-Shelf’ CD19-chimeric antigen receptor (CAR) T cells allows to identify their subset complexity and to optimize their manufacturing." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (2021): A111—A112. http://dx.doi.org/10.1136/jitc-2021-sitc2021.102.

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BackgroundUmbilical cord blood (UCB) represents a promising source of T cells for the generation of ‘off-the-shelf’ T cells engineered to express a chimeric antigen receptor (CAR). This study is aimed at understanding the composition of T cell subsets within UCB-CAR-T cells.MethodsT cells, either from UCB or peripheral mononuclear cells (PBMCs) of healthy donors, were activated in vitro with CD3/CD28 mAbs either conjugated to magnetic beads (Dynabeads) or to a colloidal polymeric nanomatrix (TransAct; Miltenyi Biotec). T cells were then transduced with lentiviral vectors encoding for CD19-CD28

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Chang, Kevin, Henry M. Delavan, Jun Zhu та ін. "Abstract PR008: Modulating the PPARγ pathway to augment NECTIN4-targeting chimeric antigen receptor (CAR) T cell therapy". Clinical Cancer Research 30, № 10_Supplement (2024): PR008. http://dx.doi.org/10.1158/1557-3265.bladder24-pr008.

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Abstract Background: We present the development of NECTIN4-CAR T cells targeting bladder cancer and evaluate the ability of thiazolidinedione, a class of anti-diabetic drugs, to specifically upregulate NECTIN4 expression and expand the therapeutic window of NECTIN4-CAR T cells. In addition, we assess efficacy of NECTIN4-CAR T cell therapy against a model of bladder cancer with acquired resistance to enfortumab vedotin (EV). Methods: NECTIN4-targeting chimeric antigen receptor (CAR) constructs were designed and cloned into a second-generation EQ-28ζ CAR backbone construct. Human primary T cells

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Guzman, Monica L. "Abstract IA07: Improving CAR T cell therapy efficacy in hematologic malignancies with low-dose total body irradiation." Clinical Cancer Research 31, no. 2_Supplement (2025): IA07. https://doi.org/10.1158/1557-3265.targetedtherap-ia07.

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Abstract Chimeric Antigen Receptor (CAR) T cell therapy represents a significant advance in the treatment of hematologic malignancies, as demonstrated by the high response rates and improved survival in diseases such as acute lymphoblastic leukemia (ALL), non-Hodgkin lymphoma (NHL), Diffuse large cell lymphoma (DLBCL) and chronic lymphocytic leukemia (CLL). The FDA has approved several CAR T cell therapies, including some approaches targeting CD19 (CART19) for adult and pediatric patients with B-cell malignancies. Response rates for CD19 CART therapy have been quite promising, reaching 80% ove

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Franscini, M., N. Traber-Walker, F. Probst, M. Gerstenberg, and S. Walitza. "Early detection and intervention of psychosis in children and adolescents in Zurich, Switzerland: Clinical Data from 2017-2022." European Psychiatry 66, S1 (2023): S1075—S1076. http://dx.doi.org/10.1192/j.eurpsy.2023.2284.

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IntroductionThe construct of a clinical high-risk (CHR) state of psychosis has been established to describe potentially prodromal symptoms which typically appear during adolescence and young adulthood. This is a very sensitive developmental period and the clinical high risk (CHR) is associated with increased functional impairment. To address the specialities in the care for this patient population a specialized outpatient care unit for early intervention in psychosis at the Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital, of the University Züric

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de Waele, Michel. "De Paris à Tours : la crise d'identité des magistrats parisiens de 1589 à 1594." Revue historique o 607, no. 3 (1998): 549–78. http://dx.doi.org/10.3917/rhis.g1998.607n3.0549.

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Résumé En mars 1589, le contrôle total de la Ligue sur Paris force Henri III à transférer les institutions du royaume à Tours. Cette décision place les magistrats parisiens dans une situation difficile, car elle les force à réfléchir sur leur identité première : en tant que catholiques et Parisiens, ils devraient demeurer dans la capitale pour protéger leur religion et leur ville ; en tant qu'officiers de la couronne, ils devraient rejoindre le roi dans son exil. Si pour certains, qu'ils soient ligueurs ou royalistes, la voie du devoir ne fait aucun doute, la plupart des membres des cours souv

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Shashikala Yalagi. "Study of vibrational spectra of zwitterionic 3-Aminobutanoic acid, as supported by DFT calculations." World Journal of Advanced Research and Reviews 16, no. 3 (2022): 1122–31. http://dx.doi.org/10.30574/wjarr.2022.16.3.1487.

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3-Aminobutanoic acid is an unnatural amino acid and by analogy with other amino acids, is represented in its zwitterionic form by R-CH(COO¯)NH3+ (where side group R = aryl, alkyl or any other group) in solid phase. Experimental IR and Raman modes near 3029, 2871, 1577, 1288 cm-1 measured for 3ABA are strongly in favor of the zwitterionic dimer structure formed of –N-H∙∙∙O–C bonding between –NH3+ and anion – CO2¯ groups. Zwitterionic monomer and dimer structures at B3LYP/6-311++G(d,p) level are computed. It has been found that the stable zwitterionic monomer and dimer structures are possible

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Zhu, Jiawei, Meini Yuan, Xin Pei, Xiaosheng Zhou, and Maohua Li. "The Effect of Stearic Acid on Microstructure and Properties of (Ti2AlC + Al2O3)p/TiAl Composites." Metals 14, no. 4 (2024): 392. http://dx.doi.org/10.3390/met14040392.

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A new type of multiphase nanoparticle-reinforced TiAl matrix composites ((Ti2AlC + Al2O3)p/TiAl composites) was successfully prepared by vacuum hot-pressing sintering using Ti powder and Al powder, which were ball-milled with different contents of stearic acid (CH3(CH2)16COOH). The component, microstructure, reaction mechanism, and mechanical properties were studied. The results indicated that the composites prepared by adding stearic acid as a process control agent during the ball-milling process not only contained γ-TiAl and α2-Ti3Al phases but also Ti2AlC and Al2O3 phases. The results of SE

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Corby, Brian. "The Secret of Bryn Estyn: The Making of a Modern Witch Hunt by Richard Webster, Orwell Press, Oxford, 2005. 722 pp. ISBN 0-95 1592-24-6 (Hbk) £25.00." Child Abuse Review 15, no. 4 (2006): 285–87. http://dx.doi.org/10.1002/car.948.

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Abrahimi, Parwiz, Jonathan Khan, Renier Brentjens, Taha Merghoub, and Jedd Wolchok. "Abstract B017: Novel mesothelin-based CAR T cells targeting MUC16 as an intravesical bladder cancer therapy." Clinical Cancer Research 30, no. 10_Supplement (2024): B017. http://dx.doi.org/10.1158/1557-3265.bladder24-b017.

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Abstract Intravesical therapies have been the mainstay of non-muscle invasive bladder cancer (BC) management; however, their efficacy is limited by toxicities, recurrences, and supply shortages. Consequently, many patients are recommended cystectomy, which is fraught with high complication rates. Thus, bladder-sparing treatments present a major, unmet clinical need. Chimeric antigen receptor (CAR) T cell therapy, wherein T cells are engineered to express an artificial receptor to a target, is an immunotherapeutic approach with efficacy in hematologic malignancies. Similar success in solid tumo

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Fajnorova, Iveta, Pauline Jeanjean, Ines Camille Azrour, et al. "Abstract B001: Double targeted therapy PSCA-CAR-T cells and PSMA-radioligand in metastatic castration-resistant prostate cancer." Clinical Cancer Research 31, no. 2_Supplement (2025): B001. https://doi.org/10.1158/1557-3265.targetedtherap-b001.

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Abstract Targeted radioligand therapy (PSMA-RLT) extends survival in advanced castration-resistant prostate cancer (CRPC) (Sartor et al., 2021), yet half of patients experiences limited responses or relapse with additional metastases (Stuparu et al., 2020). Given that metastatic CRPC has a tumor environment lacking immune infiltration and resisting immune checkpoint therapies, combination strategies that actively bring immune cells into the tumor are urgently needed (Choudhury et al., 2024). Prostate stem cell antigen (PSCA) is another promising target, as it is frequently overexpressed in adv

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Gholamin, Sharareh, Heini Natri, Yuqi Zhao, et al. "Abstract P015: Targeting SPP1 to enhance CAR T cell therapy in glioblastoma: Implications for integrating radiation therapy in resistant solid tumors." Clinical Cancer Research 31, no. 2_Supplement (2025): P015. https://doi.org/10.1158/1557-3265.targetedtherap-p015.

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Abstract In the evolving landscape of glioblastoma (GBM) treatment, clinical trials exploring chimeric antigen receptor (CAR) T cell therapies have shown promise; however, their therapeutic efficacy remains constrained, particularly due to the immunosuppressive tumor microenvironment (TME). Emerging evidence highlights that the TME, especially myeloid-driven suppressive networks, plays a central role in resistance to CAR T cell therapy. Despite progress in elucidating these mechanisms, significant ambiguities endure, particularly regarding patient-specific TME heterogeneity and its impact on t

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