Relevant bibliographies by topics / CHRNA5

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'CHRNA5'

Author: Grafiati
Published: 4 June 2021
Last updated: 15 February 2022

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Journal articles on the topic "CHRNA5"

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Meixner, Marion, Srebrena Atanasova, Winfried Padberg, and Veronika Grau. "Expression of Acetylcholine Receptors by Experimental Rat Renal Allografts." BioMed Research International 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/289656.

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Chronic allograft injury (CAI) is a major cause for renal allograft dysfunction and characterized by vasculopathies, tubular atrophy, and fibrosis. We demonstrated that numerous leukocytes interact with vascular endothelial cells of allografts and produce acetylcholine, which contributes to vascular remodeling. The cholinergic system might be a promising target for the development of novel therapies. However, neither the cellular mechanisms nor the acetylcholine receptors involved in CAI are known. Kidney transplantation was performed in the Lewis to Lewis and in the Fischer-334 to Lewis rat s
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Culverhouse, Robert C., Li-Shiun Chen, Nancy L. Saccone, et al. "Variants in the CHRNA5–CHRNA3–CHRNB4 Region of Chromosome 15 Predict Gastrointestinal Adverse Events in the Transdisciplinary Tobacco Use Research Center Smoking Cessation Trial." Nicotine & Tobacco Research 22, no. 2 (2019): 248–55. http://dx.doi.org/10.1093/ntr/ntz044.

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Abstract Introduction Reducing adverse events from pharmacologic treatment is an important goal of precision medicine and identifying genetic predictors of adverse events is a step toward this goal. In 2012, King et al. reported associations between genetic variants and adverse events in a placebo-controlled smoking cessation trial of varenicline and bupropion. Strong associations were found between gastrointestinal adverse events and 11 variants in the CHRNA5–CHRNA3–CHRNB4 region of chromosome 15, a region repeatedly associated with smoking-related phenotypes. Our goal was to replicate, in an
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Marqui, Alessandra Bernadete Trovó de, Vera Lúcia Bonfim, and Mariangela Torreglosa Ruiz. "Polimorfismos Genéticos nos Receptores Nicotínicos e Câncer de Pulmão: uma Visão Geral." Revista Brasileira de Cancerologia 57, no. 3 (2011): 421–28. http://dx.doi.org/10.32635/2176-9745.rbc.2011v57n3.677.

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Introdução: O câncer de pulmão é o mais comum de todos os tumores malignos. Responsável por 20.485 mortes, em 2008, no Brasil, e, em 90% dos casos diagnosticados, está associado ao consumo de derivados de tabaco. A nicotina é o componente primário do tabaco presente no cigarro e, variantes genéticas nos genes que codificam subunidades do receptor de acetilcolina nicotínico participam na etiologia e progressão do câncer de pulmão. Objetivo: Realizar uma revisão sobre o câncer de pulmão e polimorfismos de nucleotídeos únicos em genes codificadores de subunidades dos receptores de acetilcolina ni
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Diabasana, Zania, Jeanne-Marie Perotin, Randa Belgacemi, et al. "Chr15q25 Genetic Variant rs16969968 Alters Cell Differentiation in Respiratory Epithelia." International Journal of Molecular Sciences 22, no. 13 (2021): 6657. http://dx.doi.org/10.3390/ijms22136657.

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The gene cluster region, CHRNA3/CHRNA5/CHRNB4, encoding for nicotinic acetylcholine receptor (nAChR) subunits, contains several genetic variants linked to nicotine addiction and brain disorders. The CHRNA5 single-nucleotide polymorphism (SNP) rs16969968 is strongly associated with nicotine dependence and lung diseases. Using immunostaining studies on tissue sections and air-liquid interface airway epithelial cell cultures, in situ hybridisation, transcriptomic and cytokines detection, we analysed rs16969968 contribution to respiratory airway epithelial remodelling and modulation of inflammatio
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Buczkowski, Krzysztof, Alicja Sieminska, Katarzyna Linkowska, et al. "Association between Genetic Variants on Chromosome 15q25 Locus and Several Nicotine Dependence Traits in Polish Population: A Case-Control Study." BioMed Research International 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/350348.

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Tobacco smoking continues to be a leading cause of disease and mortality. Recent research has confirmed the important role of nicotinic acetylcholine receptor (nAChR) gene cluster on chromosome 15q 24-25 in nicotine dependence and smoking. In this study we tested the association of smoking initiation, age at onset of daily smoking, and heaviness of smoking with five single nucleotide polymorphisms (SNPs) within the CHRNA5-CHRNA3-CHRNB4 cluster. The group of 389 adult subjects of European ancestry from the north of Poland, including 212 ever (140 current and 72 former) and 177 never smokers wit
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Chen, Li-Shiun, and Laura J. Bierut. "Genomics and personalized medicine: CHRNA5-CHRNA3-CHRNB4 and smoking cessation treatment." Journal of Food and Drug Analysis 21, no. 4 (2013): S87—S90. http://dx.doi.org/10.1016/j.jfda.2013.09.041.

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Zhao, L., L.-Y. Zou, B.-F. Cheng, X.-J. Yu, J.-H. Zou, and W. Han. "Chronic obstructive pulmonary disease risk and smoking cessation changes induced by CHRNA5-A3 and CHRNB3-A6 variation in a Chinese male population." Balkan Journal of Medical Genetics 22, no. 2 (2019): 51–58. http://dx.doi.org/10.2478/bjmg-2019-0018.

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AbstractMost studies in the field of CHRNA5-A3 and CHRNB3-A6 have only focused on lung cancer risk; however, the associations with chronic obstructive pulmonary disease (COPD) risk and smoking cessation is less understood, particularly in the Chinese male population. In this study, samples from 823 male patients with COPD (non smokers: 416; still smoking: 407) and 435 smoking male healthy control subjects were performed with DNA extraction and single nucleotide polymorphism (SNP) genotyping. We studied three SNPS in two genes, namely rs667282 and rs3743073 in CHRNA5-A3 and rs4950 in CHRNB3-A6,
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Li, Zhijun, Suzhen Bao, Xiaohong Xu, Yejiang Bao, and Yongjun Zhang. "Polymorphisms of CHRNA5-CHRNA3-CHRNB4 Gene Cluster and NSCLC Risk in Chinese Population." Translational Oncology 5, no. 6 (2012): 448–52. http://dx.doi.org/10.1593/tlo.12304.

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Stephens, Sarah H., Nicole R. Hoft, Isabel R. Schlaepfer, et al. "Externalizing Behaviors are Associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 Gene Cluster." Behavior Genetics 42, no. 3 (2011): 402–14. http://dx.doi.org/10.1007/s10519-011-9514-x.

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Rosell, R., J. L. Ramirez, M. Sanchez-Ronco, et al. "Blood-based CHRNA3 single nucleotide polymorphisms (SNPs) and outcome in advanced non-small cell lung cancer (NSCLC) patients (p)." Journal of Clinical Oncology 27, no. 15_suppl (2009): 8033. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.8033.

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8033 Background: Nicotonic acetylcholine receptors (nAChRs) are associated with resistance to gemcitabine (gem), cisplatin (cis) and paclitaxel in NSCLC cell lines. Three SNPs of CHRNA3, CHRNA5 and LOC123688 increase lung cancer risk. These SNPs may have influenced outcome in p treated in our phase III trial (Cobo et al. J Clin Oncol 2007;25:2747–54). Methods: Stage IV NSCLC p were treated with customized chemotherapy based on ERCC1 mRNA expression. p in the control arm received docetaxel (doc)/cis; p in the genotypic arm with low ERCC1 levels (low genotypic group [LG]) received doc/cis; p in
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Dissertations / Theses on the topic "CHRNA5"

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Liuski, H. (Heli). "CHRNA3-CHRNA5-CHRNB4 -geenialueen assosiaatio painoindeksiin ja verenpaineeseen eri muuttujanvalintamenetelmillä." Master's thesis, University of Oulu, 2013. http://urn.fi/URN:NBN:fi:oulu-201305211326.

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Työn tavoitteena on selvittää, löytyykö CHRNA3-CHRNA5-CHRNB4 -geenialueelta assosiaatiota tarkasteltaviin vasteisiin, painoindeksiin ja verenpaineeseen. Kyseiseltä geenialueelta on aiemmin havaittu assosiaatiota tupakoimiseen, ja tämän vuoksi tutkimuksessa analysoidaan erikseen geenialueen vaikutusta tupakoimattomilla ja tupakoivilla. Geenialueelta on tutkimukseen valittu 18 SNP-kohtaa, joiden epäillään vaikuttavan vasteisiin. Tutkimusaineistona on Pohjois-Suomen syntymäkohorttitutkimus 1966, jonka populaatiorakenteen korjaamiseen on muodostettu 10 pääkomponenttia. Tässä tutkimuksessa myös arv
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Molas, Casacuberta Susanna 1985. "Nicotine addiction phenotypes in a BAC transgenic mouse model overexpressing the CHRNA5/A3/B4 genomic cluster." Doctoral thesis, Universitat Pompeu Fabra, 2012. http://hdl.handle.net/10803/104155.

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The CHRNA5/A3/B4 genomic cluster encodes for the alpha5, alpha3 and beta4 subunits of the nicotinic acetylcholine receptors (nAChRs). Human genetic studies have revealed a significant association of variants in this genomic region with nicotine dependence. However, the mechanisms through which overexpression of these three subunits may influence smoking-related behaviours is not understood. To gain insight in the possible mechanisms, we used a BAC transgenic mouse model overexpressing this cluster containing the three genes together with their transcriptional regulatory elements. We fou
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Ware, Jennifer J. "Exploring associations between the nicotinic acetylcholine receptor gene cluster CHRNA5-A3-B4 and smoking-related behaviours." Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/46871/.

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Tobacco use is the leading preventable cause of death worldwide. In order to address this epidemic, it is important that we have a thorough understanding of the aetiology of tobacco use and dependence. Twin and adoption studies have consistently demonstrated the importance of genetic factors in smoking behaviours. The advent of genome-wide technologies has greatly facilitated the search to determine which specific genetic factors contribute to tobacco use phenotypes. A locus within the nicotinic acetylcholine receptor gene cluster CHRNA5-A3-B4 has generated particular interest – that marked by
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Schlaepfer, Isabel Rubio. "Statistical and biological examination of CHRNA5/A3/B4 gene cluster variations and their association with disinhibitory behaviors." Connect to online resource, 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3337151.

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Agulhon, Cendra. "Génétique des épilepsies : Etude de l'expression de gènes candidats aux épilepsies dans les tissus prénataux humains." Montpellier 1, 1999. http://www.theses.fr/1999MON1T017.

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Smith, Ryan M. "Expression Genetics in the Human Brain: Evolution and Disease." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1291037634.

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Ahmad, Omar Akram Jerjees. "Identification of novel transcripts of CHRNA7 and CHRFAM7A in airway epithelial cells." Thesis, University of Nottingham, 2013. http://eprints.nottingham.ac.uk/13731/.

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Background: RNA splicing is a crucial process for delivering the appropriate message for protein synthesis. Most genes are affected by alternative splicing, and among these is CHRNA7. This gene encodes for the nicotinic acetylcholine α7 receptor subunit that is involved in the cholinergic anti-inflammatory pathway. This anti-inflammatory pathway is considered an important part of the human body’s defence line against tissue injury or infection and causative mechanism in COPD. Aim: The aim of the present study was to investigate the role of alternative splicing on the nature of the transcripts
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Chan, Tom. "Smectic phase transitions in chrial liquid crystals." Thesis, Massachusetts Institute of Technology, 1995. http://hdl.handle.net/1721.1/32636.

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Craffonara, Marlene [Verfasser], and Dan [Akademischer Betreuer] Rujescu. "Das Gen CHRNA7 und die Erkrankung der Schizophrenie - ein pathogenetischer Zusammenhang? / Marlene Craffonara ; Betreuer: Dan Rujescu." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2020. http://d-nb.info/1229835431/34.

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Bažant, Jan. "Obraz a Slovo, Jan za chrta dán." Master's thesis, Akademie múzických umění v Praze. Divadelní fakulta AMU. Knihovna, 2007. http://www.nusl.cz/ntk/nusl-78590.

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This text deals with the conflict betwen word and image it theatre performance, with special regard to diference between the point of wiew of director and stagedesigner. The analisis my graduite performance in witch the old Czech play Jan za chrta dán was put on stage is integral part of this work. Complete pictorial documentation of this performance is included.
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Books on the topic "CHRNA5"

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Smith, Greg Leitich. Chronal engine. Houghton Mifflin Harcourt, 2012.

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Ór ar chrann. Coiscéim, 2011.

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ill, Henry Blake, ed. The Chronal Engine. Clarion Books, 2012.

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Rashk, Abdul Qadeer. Yaadon ke chraag. Takhleqat, 1999.

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Cowley, Joy. Bó sa chrann. IMRU, 2004.

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Vũ, Hạnh. Chrat ngọc. s.n., 1991.

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Pavle, Mijoviạc, and Myjučković Slavko, eds. Istorija o Chrnoj gori. Leksikografaki zavod Crne Gore, 1985.

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Aodha, Colette Nic. Faoi chrann cnó capaill. Coiscéim, 2000.

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Eisner, Pavel. Chram i tvrz. Pluto, 1997.

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Nguynen, Thanh Tùng. Dư chran: Titeu thuyret. NXB Huoi nhà văn, 2006.

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Book chapters on the topic "CHRNA5"

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Li, Ming D. "Involvement of Variants in Gene Clusters CHRNA5/A3/B4 on Chromosome 15 to Smoking Behaviors and Lung Cancer." In Tobacco Smoking Addiction: Epidemiology, Genetics, Mechanisms, and Treatment. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-7530-8_5.

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Marasca, Federica, Alice Cortesi, and Beatrice Bodega. "3D COMBO chrRNA–DNA–ImmunoFISH." In Methods in Molecular Biology. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0664-3_16.

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Mathur, Shubh. "The Burning of Chrar-i-Sharief." In The Human Toll of the Kashmir Conflict. Palgrave Macmillan US, 2016. http://dx.doi.org/10.1057/9781137546227_4.

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Zerrouki, Lahcen, Warda Essarhane, Somia Hamil, and Mounia Baha. "The Earthworm Fauna of Chréa National Park (Algeria)." In Recent Advances in Environmental Science from the Euro-Mediterranean and Surrounding Regions (2nd Edition). Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-51210-1_216.

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Li, Ming D. "Contribution of Variants in CHRNB3/A6 Gene Cluster on Chromosome 8 to Smoking Dependence." In Tobacco Smoking Addiction: Epidemiology, Genetics, Mechanisms, and Treatment. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-7530-8_6.

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Bendjoudi, Djamel, Faiza Marniche, Lilia Takdjout, and Manuel Epalanga. "First Report on the Copro-parasitology of Striped Hyena, African Golden Wolf and Red Fox in Chrea National Park, (Algeria)." In Recent Advances in Environmental Science from the Euro-Mediterranean and Surrounding Regions (2nd Edition). Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-51210-1_215.

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Lee, Sung-Ha, Elizabeth S. Barrie, Wolfgang Sadee, and Ryan M. Smith. "Nicotine Dependence and the CHRNA5/CHRNA3/CHRNB4 Nicotinic Receptor Regulome." In Neuroscience of Nicotine. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-813035-3.00043-5.

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Goldman, David. "The Genetic Basis of Addictive Disorders." In Neurobiology of Mental Illness, edited by Antonello Bonci and Nora D. Volkow. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199934959.003.0052.

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The quantitative inheritance of addictions presaged identification of genes modulating risk. Vulnerability is mediated both by agent-specific and non-specific factors. Genomic views include Genome Wide Association which detected CHRNA5, a nicotinic receptor subunit that modulates vulnerability to smoking. Sequencing detected a population-specific stop codon in HTR2B, a serotonin receptor that modulates impulsivity and other addiction-related processes. The loci identified account for a small portion of inherited liability. In several instances larger effects have been observed on processes such as emotionality, impulsivity and metabolism that mediate vulnerability. Although we do not possess a set of genetic markers predictive of treatment response, several genes including OPRM1 which has been linked to response of alcoholic patients to naltrexone, have predictive value.
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"CHRNA7 Deletions." In Encyclopedia of Autism Spectrum Disorders. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-91280-6_300332.

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"Chrap m." In Wörterbuch GeoTechnik/Dictionary Geotechnical Engineering. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-33335-4_30191.

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Conference papers on the topic "CHRNA5"

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Korytina, Guly F., Leysan Z. Akhmadishina, Kristina Y. Knyazeva, Yuliya G. Aznabaeva, Tatyana V. Viktorova, and Shamil Z. Zagidullin. "Replication association studyIREB2, CHRNA5, CHRNA3, CHRNB4, FAM13A, HTR4, andHHIPgenes polymorphisms with chronic obstructive pulmonary disease in Tatar population from Russia." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa1198.

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Sun, Haiji, Liguo An, Yun Zhao, et al. "CHRNA5 variants related to nicotine sensitivity in lung cancer in vitro." In 2010 3rd International Conference on Biomedical Engineering and Informatics (BMEI). IEEE, 2010. http://dx.doi.org/10.1109/bmei.2010.5639447.

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Diabasana, Z., R. Belgacemi, J. Ancel, et al. "Role of the Nicotinic Acetylcholine Receptor Chrna5 Gene Mutation in Chronic Obstructive Pulmonary Disease." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4018.

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Chikova, Anna, and Sergei Grando. "Abstract 1331: Ethnic-specific polymorphisms in CHRNA3 and CHRNA9 genes." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-1331.

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Scherf, David B., Narek F. Sarkisyan, Hanna T. Jacobsson, et al. "Abstract 4946: The nicotinic acetylcholine receptor genes CHRNA3 and CHRNB4 are epigenetically deregulated in lung tumorigenesis." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-4946.

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Ishii, Takeo, Akihiko Gemma, and Kozui Kida. "Association Between Emphysema And Genetic Variations Of Chrna3." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a6012.

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Thanyada, Sukmanee, Wongravee Kanet, Kitahama Yasutaka, et al. "Chrial discrimination by TERS." In Asian Spectroscopy Conference 2020. Institute of Advanced Studies, Nanyang Technological University, 2020. http://dx.doi.org/10.32655/asc_8-10_dec2020.23.

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Ozaki, Yukihiro. "chrial discrimination by TERS." In Enhanced Spectroscopies and Nanoimaging 2021, edited by Prabhat Verma and Yung Doug Suh. SPIE, 2021. http://dx.doi.org/10.1117/12.2594427.

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Foreman, Marilyn G., Craig P. Hersh, Carla Grabianowski, Dawn DeMeo, Gerard J. Criner, and Edwin K. Silverman. "CHRNA3/5, IREB2, And HHIP Are Associated With COPD In African Americans." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a2895.

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Hardin, Megan, Jan Zielinski, Emily S. Wan, et al. "HHIP, CHRNA3/5 And IREB2 Are Associated With Severe COPD In Poland." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a1757.

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