Log in

Relevant bibliographies by topics / Chromones / Journal articles

To see the other types of publications on this topic, follow the link: Chromones.

Journal articles on the topic 'Chromones'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Chromones.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Miliutina, Mariia, Syeda Abida Ejaz, Viktor O. Iaroshenko, Alexander Villinger, Jamshed Iqbal, and Peter Langer. "Synthesis of 3,3′-carbonyl-bis(chromones) and their activity as mammalian alkaline phosphatase inhibitors." Organic & Biomolecular Chemistry 14, no. 2 (2016): 495–502. http://dx.doi.org/10.1039/c5ob01350j.

Full text

Abstract:

Hitherto unknown 3,3′-carbonyl-bis(chromones) 8, dimeric chromones bridged by a carbonyl group, were prepared by reaction of chromone-3-carboxylic acid chloride with 3-(dimethylamino)-1-(2-hydroxyphenyl)-2-propen-1-ones 9.

APA, Harvard, Vancouver, ISO, and other styles

2

Stoermer, MJ, and DP Fairlie. "A Selective and Versatile Synthesis of Substituted Chromones via Addition of Phenols to Dimethyl Acetylenedicarboxylate." Australian Journal of Chemistry 48, no. 3 (1995): 677. http://dx.doi.org/10.1071/ch9950677.

Full text

Abstract:

Despite many published syntheses of chromones, none has been reported to be both selective for chromones and tolerant of ring substitution. The addition of substituted phenols to dimethyl acetylenedicarboxylate is now reported as a versatile high yield initial step in a simple three-step synthesis of chromone 2-carboxylic acids. Triethylamine being used to deprotonate the substituted phenol, the addition to dimethyl acetylenedicarboxylate proceeds under mild conditions and tolerates a wide range of functional groups on the phenol. Although not stereoselective, both fumarate and maleate aryloxy

APA, Harvard, Vancouver, ISO, and other styles

3

Samar, Ghosh, and Pratim Maiti Partha. "APPLICATIONS OF CHROMONES: RECENT TRENDS." International Journal of Advance and Applied Research 3, no. 4 (2023): 115–25. https://doi.org/10.5281/zenodo.7654046.

Full text

Abstract:

The rigid bicyclic chromone fragment has been classified as a privileged structure in drug discovery, due to its use in a wide variety of pharmacologically active compounds; few examples as therapeutic agents chromones are used as scaffolds for the development of bioactive compounds, the application in medicinal chemistry, such as preparation of fluorescence probes, due to photochemical properties of chromones have been also mentioned.

APA, Harvard, Vancouver, ISO, and other styles

4

Benny, Anjitha Theres, Sonia D. Arikkatt, Cijo George Vazhappilly, et al. "Chromone, A Privileged Scaffold in Drug Discovery: Developments in the Synthesis and Bioactivity." Mini-Reviews in Medicinal Chemistry 22, no. 7 (2022): 1030–63. http://dx.doi.org/10.2174/1389557521666211124141859.

Full text

Abstract:

: Chromones are the class of secondary metabolites that broadly occur in the plant kingdom in a noticeable quantity. This rigid bicyclic system has been categorized “as privileged scaffolds in compounds” in medicinal chemistry. Their wide biological responses have made them an important moiety in a drug discovery program. This review provides updates on the various methods of synthesis of chromones and biological applications in medicinal chemistry. Various synthetic strategies for the construction of chromones include readily available phenols, salicylic acid and its derivatives, ynones, chal

APA, Harvard, Vancouver, ISO, and other styles

5

Wang, Xiaohong, Menglin Peng, Yijin Wang та ін. "Eco-Friendly and Efficient Synthesis of 2-Hydroxy-3-Hydrazono-Chromones Through α,β-C(sp2)–H Bond Difunctionalization/Chromone Annulation Reaction of o-Hydroxyaryl Enaminones, Water, and Aryldiazonium Salts". Molecules 30, № 6 (2025): 1194. https://doi.org/10.3390/molecules30061194.

Full text

Abstract:

A novel, eco-friendly, and efficient method for constructing 2,3-disubstituted chromone skeletons from readily available water, o-hydroxyaryl enaminones (o-HPEs), and aryldiazonium salts has been developed under mild reaction conditions. This α,β-C(sp2)–H bond difunctionalization/chromone annulation reaction strategy is achieved by building two C(sp3)–O bonds and a C(sp2)-N bond, which provides a practical pathway for the preparation of 2-hydroxy-3-hydrazono-chromones in moderate to excellent yields, enabling broad substrate scope and good functional group tolerance, as well as gram-scale synt

APA, Harvard, Vancouver, ISO, and other styles

6

Mrug, Galyna, and Mykhaylo Frasinyuk. "Advances in chemistry of chromone aminomethyl derivatives." French-Ukrainian Journal of Chemistry 3, no. 2 (2015): 21–39. http://dx.doi.org/10.17721/fujcv3i2p21-39.

Full text

Abstract:

Chromones play an important role in the design and discovery of new pharmacologically active compounds. A large volume of reports dedicated to synthesis and study of properties of nitrogen-containing chromone derivatives show important role of chromone alkaloid-like compounds. The present review covers achievements in the field of synthesis of chromone aminomethyl derivatives as one of perspective scaffolds.

APA, Harvard, Vancouver, ISO, and other styles

7

Deharkar, Pravin, Shridhar Satpute, and Deepa Panhekar. "Synthetic Routes and Biological Activities of Chromone Scaffolds: An Overview." Asian Journal of Chemistry 35, no. 4 (2023): 771–93. http://dx.doi.org/10.14233/ajchem.2023.23442.

Full text

Abstract:

The central backbones of natural assets and therapeutic medications are chromone and flavone. Utilizing such preferred chalcone analogs in drug research has shown a successful blueprint, yielding new hits/leads and fast optimization procedures. Chromone can create novel molecules with pharmacological promise, particularly in neurological, inflammatory, infectious diseases, cancer and diabetes. The current perspective focuses mainly on flavones and flavonoids of biological significance, such as chromon-4-one analogs, both synthetic and natural sources. Furthermore, because drug repurposing is n

APA, Harvard, Vancouver, ISO, and other styles

8

Yu, Qing, Yunyun Liu, and Jie-Ping Wan. "Transition metal-free synthesis of 3-trifluoromethyl chromones via tandem C–H trifluoromethylation and chromone annulation of enaminones." Organic Chemistry Frontiers 7, no. 18 (2020): 2770–75. http://dx.doi.org/10.1039/d0qo00855a.

Full text

Abstract:

The synthesis of 3-trifluoromethyl chromones has been realized via transition metal-free reactions of o-hydroxyphenyl enaminones and the Langlois reagent via cascade C–H trifluoromethylation and chromone annulation.

APA, Harvard, Vancouver, ISO, and other styles

9

Benny, Anjitha Theres, and Ethiraj Kannatt Radhakrishnan. "Advances in the site-selective C-5, C-3 and C-2 functionalization of chromones via sp² C–H activation." RSC Advances 12, no. 6 (2022): 3343–58. http://dx.doi.org/10.1039/d1ra08214k.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Lei, Jie, Yong Li, Liu-Jun He, et al. "Expeditious access of chromone analogues via a Michael addition-driven multicomponent reaction." Organic Chemistry Frontiers 7, no. 8 (2020): 987–92. http://dx.doi.org/10.1039/d0qo00145g.

Full text

Abstract:

A Michael addition-driven four-component reaction (4-CR) with four Ugi inputs was developed and utilized for the synthesis of chromone derivatives and tetrazole substituted chromones under mild reaction conditions.

APA, Harvard, Vancouver, ISO, and other styles

11

Luo, Tian, Jie-Ping Wan та Yunyun Liu. "Toward C2-nitrogenated chromones by copper-catalyzed β-C(sp2)–H N-heteroarylation of enaminones". Organic Chemistry Frontiers 7, № 9 (2020): 1107–12. http://dx.doi.org/10.1039/d0qo00065e.

Full text

Abstract:

The synthesis of C2-nitrogenated chromones has been performed via reactions of enaminones and nitrogen nucleophiles based on an unconventional β-C–H bond functionalization and a featured chromone annulation of enaminones.

APA, Harvard, Vancouver, ISO, and other styles

12

Hammadi, Mohamed, Oualid Talhi, Artur Silva, et al. "Regioselective and Catalyst-Free Epoxidation of (E)-3-[3-(2-Hydroxyaryl)-3-oxoprop-1-en-1-yl]chromones." Synlett 29, no. 20 (2018): 2633–37. http://dx.doi.org/10.1055/s-0037-1611082.

Full text

Abstract:

The uncatalyzed reaction of hydrogen peroxide with (E)-3-[3-(2-hydroxyaryl)-3-oxoprop-1-en-1-yl]chromones resulted in a regioselective epoxidation of the chromone intracyclic C(2)=C(3) double bond to afford unique isomeric (E)-7a-[3-(2-hydroxyphenyl)-3-oxoprop-1-en-1-yl]-1aH-oxireno[2,3-b]chromen-7(7aH)-ones in high yields. 2D NMR and single-crystal X-ray diffraction were used to elucidate the structures of the chromanone epoxides. Density functional theoretical studies demonstrated a high electrophilicity of the starting chromones.

APA, Harvard, Vancouver, ISO, and other styles

13

Shablykina, Olga, Viktoriia Moskvina, and Volodymyr Khilya. "Features of the synthesis and biological evaluation of 3-(carboxyphenyl)chromones." Ukr. Bioorg. Acta 2020, Vol. 15, N2 15, no. 2 (2020): 3–12. http://dx.doi.org/10.15407/bioorganica2020.02.00.

Full text

Abstract:

Flavonoids and their derivatives have historically been a source of therapeutic agents. Every year, more and more data is published on new flavonoid compounds, both synthetic and isolated from natural sources, and their innumerable physiological and pharmacological activities. This review presents synthetic routes towards 3-(carboxyphenyl)chromones and evaluation of their biological activity as published in both journal and patent literature. We have focused specifically on the 3-(carboxyphenyl)chromones, because while methods of synthesis and biological activity of 2(3)-substituted and 2,3-di

APA, Harvard, Vancouver, ISO, and other styles

14

Shablykina, Olga V., Viktoriia S. Moskvina, and Volodymyr P. Khilya. "Features of the synthesis and biological evaluation of 3-(carboxyphenyl)chromones." Ukrainica Bioorganica Acta 15, no. 2 (2020): 3–12. http://dx.doi.org/10.15407/bioorganica2020.02.003.

Full text

Abstract:

Flavonoids and their derivatives have historically been a source of therapeutic agents. Every year, more and more data is published on new flavonoid compounds, both synthetic and isolated from natural sources, and their innumerable physiological and pharmacological activities. This review presents synthetic routes towards 3-(carboxyphenyl)chromones and evaluation of their biological activity as published in both journal and patent literature. We have focused specifically on the 3-(carboxyphenyl)chromones, because while methods of synthesis and biological activity of 2(3)-substituted and 2,3-di

APA, Harvard, Vancouver, ISO, and other styles

15

Guo, Yanhui, Shanshan Zhong, Li Wei, and Jie-Ping Wan. "Transition-metal-free synthesis of 3-sulfenylated chromones via KIO3-catalyzed radical C(sp2)–H sulfenylation." Beilstein Journal of Organic Chemistry 13 (September 27, 2017): 2017–22. http://dx.doi.org/10.3762/bjoc.13.199.

Full text

Abstract:

The reactions between o-hydroxylphenyl-functionalized enaminones and sulfonyl hydrazines providing 3-sulfenylated chromones via domino chromone ring construction and C(sp2)–H bond sulfenylation have been achieved under transition-metal-free conditions by using KIO3 as the only catalyst.

APA, Harvard, Vancouver, ISO, and other styles

16

Shokol, Tatyana, Natalia Gorbulenko, and Khilya Volodymyr. "Synthesis of linear hetarenochromones based on 7-hydroxy-6-formyl(acetyl)chromones." French-Ukrainian Journal of Chemistry 9, no. 1 (2021): 70–96. http://dx.doi.org/10.17721/fujcv9i1p70-96.

Full text

Abstract:

Fused chromones are attracting increasing attention as novel therapeutic agents due to their wide distribution in nature, effective bioactivities and low toxicity. 6-Carbonyl-7-hydroxychromones proved to be versatile synthons for the synthesis of linear hetarenochromones by annulation of heterocycle to the chromone core. The present review is focused on the syntheses of furo[3,2-g]chromones, pyrano[3,2-g]chromones and some of their N-containing analogues, namely chromeno[6,7-d]isoxazoles, pyrano[3’,2’:6,7]chromeno[4,3-b]pyridine-5,11-diones and pyrano[3’,2’:6,7]chromeno[4,3-c]pyridine-5,11-dio

APA, Harvard, Vancouver, ISO, and other styles

17

Rao, B. Kanakadurga, and Y. Jayaprakash Rao. "An Efficient and Facile Synthesis of Novel Triazole C-N Linked Chromone Hybrids." Asian Journal of Chemistry 32, no. 7 (2020): 1806–8. http://dx.doi.org/10.14233/ajchem.2020.22734.

Full text

Abstract:

A series of new C3-N1 directly linked chromone/1,2,3-triazole molecular hybrids synthesized by adopting low cost effective CuI catalyzed azide-alkyne 1,3-dipolar cycloaddition (Cu-AAC triazole annulation) from chromone-3-aldehyde via key intermediates 3-azidochromone, synthesized from another intermediate 3-hydroxychromone. These synthetic 1,2,3-triazole embedded chromones are the new addition to the click chemistry family. The structures of final products established by IR, NMR and mass spectral analysis.

APA, Harvard, Vancouver, ISO, and other styles

18

Sugiyama, Takuji, Yuji Narukawa, Shunsuke Shibata, Ryo Masui, and Fumiyuki Kiuchi. "New 2-(2-Phenylethyl)chromone Derivatives and Inhibitors of Phosphodiesterase (PDE) 3A from Agarwood." Natural Product Communications 11, no. 6 (2016): 1934578X1601100. http://dx.doi.org/10.1177/1934578x1601100624.

Full text

Abstract:

The MeOH extract of agarwood showed inhibitory activity against phosphodiesterase (PDE) 3A. Fractionation of the extract led to the isolation of two new 2-(2-phenylethyl)chromones, 6,8-dihydroxy-2-[2-(4′-methoxyphenyl)ethyl]chromone (6), and 6,7-dihydroxy-2-(2-phenylethyl)chromone (8), together with six known compounds. All isolated compounds were tested for their PDE 3A inhibitory activity using fluorescence polarization method. Compound 7 showed PDE 3 A inhibitory activity with IC50 of 4.83 μM.

APA, Harvard, Vancouver, ISO, and other styles

19

Shokol, Tatyana, Oleg Lozinski, Natalia Gorbulenko, and Volodymyr Khilya. "The synthesis of angular heteroarenochromones based on 7-hydroxy-8-carbonylchromones." French-Ukrainian Journal of Chemistry 5, no. 2 (2017): 68–94. http://dx.doi.org/10.17721/fujcv5i2p68-94.

Full text

Abstract:

The present review highlights advanced strategies to the synthesis of the chromones annulated with O- and N-containing heterocycles at C(7)-C(8) bond. Due to the prevalence of such motives in different kinds of natural flavonoids and some alkaloids, fused chromones have attracted a great deal of attention so far. On the other hand a wide range of biological activities is displayed by the compounds of this type both among naturally occurring flavonoids and their synthetic analogues. 8-Carbonyl-7-hydroxychromones proved to be versatile synthones for the synthesis of angular hetarenochromones via

APA, Harvard, Vancouver, ISO, and other styles

20

Maicheen, Chirattikan, Chokchaloemwat Churnthammakarn, Nichapat Pongsroypech, et al. "One-Pot Synthesis and Evaluation of Antioxidative Stress and Anticancer Properties of an Active Chromone Derivative." Molecules 28, no. 7 (2023): 3129. http://dx.doi.org/10.3390/molecules28073129.

Full text

Abstract:

Chromones are the structural building blocks of several natural flavonoids. The synthesis of chromones, which contain a hydroxy group on the ring, presents some challenges. We used the one-pot method to synthesize ten chromone derivatives and two related compounds using modified Baker-Venkataraman reactions. The structures were confirmed using FT-IR, 1H NMR, 13C NMR, and HRMS. The in vitro antioxidant assay revealed that compounds 2e, 2f, 2j, and 3i had potent antioxidant activity and that all these synthesized compounds, except those containing nitro groups, were harmless to normal cells. In

APA, Harvard, Vancouver, ISO, and other styles

21

Yu, Meng, Yangyang Liu, Jian Feng, et al. "Remarkable Phytochemical Characteristics of Chi-Nan Agarwood Induced from New-Found Chi-Nan Germplasm of Aquilaria sinensis Compared with Ordinary Agarwood." International Journal of Analytical Chemistry 2021 (April 10, 2021): 1–10. http://dx.doi.org/10.1155/2021/5593730.

Full text

Abstract:

Wild Chi-Nan agarwood is regarded as the highest quality agarwood from Aquilaria spp. However, the comprehensive research on chemical composition of wild Chi-Nan agarwood is limited. An integrated strategy using SHS-GC-MS and UPLC-Q/Tof-MS was applied to explore the phytochemical characteristics of a kind of agarwood induced from a newly identified germplasm of Chi-Nan A. sinensis. Progenesis QI and MS-Dial were used to preprocess the UPLC-Q/Tof-MS and GC-MS raw data, respectively. Principle component analysis (PCA) and orthogonal partial least squares to latent structure-discriminant analysis

APA, Harvard, Vancouver, ISO, and other styles

22

Li, Ming, Zinong Yang, Zhou Hong, Daping Xu, ZhiHui Li, and Shengjie Wang. "Effects of different clones and inducing time on agarwood quality in grafted Qi-Nan Aquilaria sinensis (Lour.) spreng." PLOS One 20, no. 7 (2025): e0327514. https://doi.org/10.1371/journal.pone.0327514.

Full text

Abstract:

Agarwood is the resinous part of the injured tree of the Aquilaria species of the Thymelaeceae family, Qi-Nan is a type of agarwood that forms easily and benefits from a shortened inducing time, noted for features like its substantial resin, (2-phenylethyl) chromone and 2-[2-(4-methoxyphenyl) ethyl] chromone content. Although the content of agarotetrol in Qi-Nan is very low, it is still an important indicator for the agarwood quality. A validated method was developed to precisely quantify both agarotetrol and two aforementioned chromones, as well as ethanal extracts, within Qi-Nan to explore h

APA, Harvard, Vancouver, ISO, and other styles

23

Langer, Peter. "Domino reactions of chromones with activated carbonyl compounds." Beilstein Journal of Organic Chemistry 20 (May 29, 2024): 1256–69. http://dx.doi.org/10.3762/bjoc.20.108.

Full text

Abstract:

Domino reactions of chromones with activated carbonyl compounds, such as dimethyl acetone-1,3-dicarboxylate and 1,3-diphenylacetone, and with 1,3-bis(silyloxy)-1,3-butadienes, electroneutral equivalents of 1,3-dicarbonyl dianions, allow for a convenient synthesis of a great variety of products. The regioselectivity and course of the reaction depends of the substituent located at carbon C3 of the chromone moiety and also on the type of nucleophile employed.

APA, Harvard, Vancouver, ISO, and other styles

24

Boutoute, Patrick, and Guy Mousset. "Réduction électrochimique régiosélective d'aroyl-2- ou d'acetyl-2 chromones en milieu non aqueux." Canadian Journal of Chemistry 70, no. 8 (1992): 2266–75. http://dx.doi.org/10.1139/v92-285.

Full text

Abstract:

The electrochemical behaviour of chromones substituted in position 2 by benzoyl or acetyl groups was studied by cyclic voltammetry in a nonaqueous solvent. Self-protonation reactions were observed with compounds possessing a phenol function on the benzoyl group. Macroelectrolyses achieved in the presence of a proton donor afford a regioselective reduction of the carbonyl function in position 2 of the benzoyl-2 chromone and of the double bond for the acetyl-2 chromone. Moreover the further reduction leads to the formation of thermally unstable dimers, which may give homolytic cleavage to free r

APA, Harvard, Vancouver, ISO, and other styles

25

Choi, Hwanho, Minsik Min, Qian Peng, Dahye Kang, Robert S. Paton, and Sungwoo Hong. "Unraveling innate substrate control in site-selective palladium-catalyzed C–H heterocycle functionalization." Chemical Science 7, no. 6 (2016): 3900–3909. http://dx.doi.org/10.1039/c5sc04590h.

Full text

Abstract:

Pd(ii)-catalyzed direct arylation of chromones and enaminones gives divergent site-selectivities. Computational and experimental studies reveal a switch in mechanism, from a C3-selective CMD mechanism to a C2-selective carbopalladation pathway. This model accounts for the opposite selectivities of enaminone and chromone, and also correctly predicts selectivities for the C–H functionalization of heteroaromatic substrates as a function of the coupling partner.

APA, Harvard, Vancouver, ISO, and other styles

26

Tarasenko, Dmytro O., Andriy Y. Chumak, Oleksii O. Kolomoitsev, Volodymyr M. Kotliar, and Alexander D. Roshal. "Synthesis of a New Series of Chromones Based on Formylthiazoles." Journal of Organic and Pharmaceutical Chemistry 21, no. 4 (2023): 3–10. http://dx.doi.org/10.24959/ophcj.23.292844.

Full text

Abstract:

A preparative approach to thiazole-containing chromone derivatives has been developed by modifying the corresponding aldehydes with their further transformation into propenone derivatives, and finally introducing them into the Algar-Flynn-Oyamada reaction. Several methods for obtaining propenones have been analyzed, and the most effective and practically convenient one has been found. The thiazole-containing analogs of chromones obtained have a great potential as probes for a wide range of studies.

APA, Harvard, Vancouver, ISO, and other styles

27

Wei, Qi Di, Yi-Ming Yao, Shun-Qin Chang, et al. "DBU-Catalyzed Inter- and Intramolecular Double Michael Addition of Donor–Acceptor Chromone-Pyrazolone/Benzofuranone Synthons: Access to Spiro-Pyrazolone/Benzofuranone-Hexahydroxanthone Hybrids." Synthesis 52, no. 01 (2019): 85–97. http://dx.doi.org/10.1055/s-0037-1610728.

Full text

Abstract:

A DBU-catalyzed inter- and intramolecular double Michael addition of donor–acceptor chromone-pyrazolone/benzofuranone synthons and 3-methyl-4-nitro-5-alkenylisoxazoles has been established, which constructed structurally diverse spiro-pyrazolone/benzofuranone-hexahydroxanthone hybrids bearing five consecutive stereocenters in good yields (up to 91%) with high diastereoselectivities (up to >20:1 dr). Moreover, this strategy further expanded the synthetic potential of bifunctional donor–acceptor chromones, and demonstrated great potential for applications in medicinal chemistry.

APA, Harvard, Vancouver, ISO, and other styles

28

Baruah, Prayasee, Mostofa Ataur Rohman, Semen O. Yesylevskyy, and Sivaprasad Mitra. "Therapeutic potency of substituted chromones as Alzheimer’s drug: Elucidation of acetylcholinesterase inhibitory activity through spectroscopic and molecular modelling investigation." BioImpacts 9, no. 2 (2019): 79–88. http://dx.doi.org/10.15171/bi.2019.11.

Full text

Abstract:

Introduction: Documentation on the potency of chromones as acetylcholinesterase (AChE) antagonists has paved the way for the design and usage of new chromone analogues as inhibitors of AChE modelled on the hypothesis based on cholinergic pathway of Alzheimer’s disease (AD). Here, 2 minimally substituted chromones, namely 3-cyanochromone (CyC) and 7-amino-3-methylchromone (AMC), were checked for their AChE inhibition efficacies and plasma protein modulation. Methods: Colorimetric enzymatic assay as well as fluorescence measurements were performed for obtaining the experimental results, which we

APA, Harvard, Vancouver, ISO, and other styles

29

Talhi, Oualid, Norah Bennamane, Artur Silva, et al. "Catalyst-Free One-Pot Synthesis of Chromeno-Imidazo-Pyridinones by an Aza-Michael Addition/Rearrangement/Heterocyclization Tandem Reaction." Synlett 29, no. 11 (2018): 1437–40. http://dx.doi.org/10.1055/s-0037-1609684.

Full text

Abstract:

A one-pot synthesis of a novel series of chromeno-imidazo-pyridinone derivatives from 3-[(2-hydroxyphenyl)-3-oxoprop-1-en-1-yl]chromones and ethane-1,2-diamine at room temperature under catalyst-free conditions has been successfully developed. This approach involves a tandem aza-Michael addition reaction, a chromone-to-chromanone rearrangement, and a heterocyclization sequence, leading to chromeno-imidazo-pyridinone polyheterocycles. The structure and absolute configurations of the new compounds were elucidated by a combination of 1D- and 2D-NMR analyses and single-crystal X-ray diffraction.

APA, Harvard, Vancouver, ISO, and other styles

30

Ipe, Reshma Susan, Sunil Kumar, Feba Benny, et al. "A Concise Review of the Recent Structural Explorations of Chromones as MAO-B Inhibitors: Update from 2017 to 2023." Pharmaceuticals 16, no. 9 (2023): 1310. http://dx.doi.org/10.3390/ph16091310.

Full text

Abstract:

Monoamine oxidases (MAOs) are a family of flavin adenine dinucleotide-dependent enzymes that catalyze the oxidative deamination of a wide range of endogenous and exogenous amines. Multiple neurological conditions, including Parkinson’s disease (PD) and Alzheimer’s disease (AD), are closely correlated with altered biogenic amine concentrations in the brain caused by MAO. Toxic byproducts of this oxidative breakdown, including hydrogen peroxide, reactive oxygen species, and ammonia, can cause oxidative damage and mitochondrial dysfunction in brain cells. Certain MAO-B blockers have been recogniz

APA, Harvard, Vancouver, ISO, and other styles

31

Zhang, Jinhua, Luxiao Chen, Junna Qiu, et al. "Simultaneous Determination of Six Chromones in Saposhnikoviae Radix via Quantitative Analysis of Multicomponents by Single Marker." Journal of Analytical Methods in Chemistry 2020 (April 14, 2020): 1–13. http://dx.doi.org/10.1155/2020/7867046.

Full text

Abstract:

A method, quantitative analysis of multicomponents by single marker (QAMS), was established and fully verified based on high-performance liquid chromatography (HPLC) for simultaneous determination of six chromone indicators of Saposhnikoviae Radix (SR). In the present study, cimifugin (C), 5-O-methylvisamminol (V), hamaudol (H), and their corresponding glycosides, prim-O-glucosylcimifugin (GC), 4′-O-β-D-glucosyl-5-O-methylvisamminol (GV), and sec-O-glucosylhamaudol (GH), were selected as bioactive constituents and indicators for the quality evaluation of SR. GV was chosen as the unique referen

APA, Harvard, Vancouver, ISO, and other styles

32

Zarate-Hernández, Carlos, Unnamatla M. V. Basavanag, and Rocío Gámez-Montaño. "Synthesis of Imidazo[1,2-a]pyridine-Chromones via Microwave-Assisted Groebke-Blackburn-Bienaymé Reaction." Proceedings 41, no. 1 (2019): 68. http://dx.doi.org/10.3390/ecsoc-23-06652.

Full text

Abstract:

A series of imidazo[1,2-a]pyridine-chromones were synthesized by microwave-assisted Groebke–Blackburn–Bienaymé reaction (GBBR) under eco-friendly conditions (20 mol% ammonium chloride catalyst in EtOH). Chromones and imidazo[1,2-a]pyridines are a privileged core of high interest in medicinal chemistry.

APA, Harvard, Vancouver, ISO, and other styles

33

Martínez-Cifuentes, Maximiliano, Boris Weiss-López, and Ramiro Araya-Maturana. "Theoretical Study about the Effect of Halogen Substitution on the Reactivity of Antitumor 3-Formylchromones and Their Free Radicals." Journal of Chemistry 2017 (2017): 1–5. http://dx.doi.org/10.1155/2017/9254831.

Full text

Abstract:

The mandatory presence of a chlorine atom on the aromatic ring of 6-hydroxy-3-formyl angular chromones, on the respiration inhibition of mammary carcinoma mouse, is explained through a computational study of these compounds. This study analyzes the reactivity of the neutral molecules and their free radicals, in gas phase and with water solvation, incorporated by the polarizable continuum medium (PCM) approach. Electrophilic reactivities were evaluated using Fukui (f+) and Parr (P+) functions. The stabilities of radical species formed by the abstraction of a hydrogen atom from the O-H bond were

APA, Harvard, Vancouver, ISO, and other styles

34

Zhang, Xin-Wen, Yan-Song Ye, Fan Xia, Xing-Wei Yang, and Gang Xu. "Diverse Polyphenols from Hypericum faberi." Natural Products and Bioprospecting 9, no. 3 (2019): 215–21. http://dx.doi.org/10.1007/s13659-019-0206-1.

Full text

Abstract:

Abstract Six new polyphenols with different isoprenylated xanthones, isoprenylated acylphloroglucinols, and chromone architectures, hyperfaberols A–F (1–6), were isolated from the whole plants of Hypericum faberi along with seven other related known compounds. In which hyperfaberols A/B (1/2) and 12–13 were isoprenylated xanthones, hyperfaberols C–E (3–5) and 8–11 were seven isoprenylated acylphloroglucinol derivatives, while 6–7 were two chromones. Their structures were elucidated by comprehensive analysis of their spectroscopic data as well as detailed comparison with the literature data. Co

APA, Harvard, Vancouver, ISO, and other styles

35

Saloutin, V. I., Z. E. Skryabina, I. T. Bazyl', and O. N. Chupakhin. "Novel fluorinated chromones." Journal of Fluorine Chemistry 65, no. 1-2 (1993): 37–41. http://dx.doi.org/10.1016/s0022-1139(00)80470-4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Saloutin, V. I., Z. E. Skryabina, I. T. Bazyl, and O. N. Chupahin. "Novel fluorinated chromones." Journal of Fluorine Chemistry 58, no. 2-3 (1992): 350. http://dx.doi.org/10.1016/s0022-1139(00)80815-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Muñoz-López, F. "Requiem for chromones?" Allergologia et Immunopathologia 30, no. 2 (2002): 53–54. http://dx.doi.org/10.1016/s0301-0546(02)79089-7.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Bandyopadhyay, Chandrakanta, Suman Panja, Sourav Maiti, and Subhabrata Banerjee. "One-Pot Synthesis of Pyrano[3,4-b]chromones from Chromone-3-carbaldehyde." Synlett 2010, no. 13 (2010): 1909–14. http://dx.doi.org/10.1055/s-0030-1258496.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Gautam, Raju, Amit Srivastava, and Sanjay M. Jachak. "Determination of Chromones in Dysophylla stellata by HPLC: Method Development, Validation and Comparison of Different Extraction Methods." Natural Product Communications 5, no. 4 (2010): 1934578X1000500. http://dx.doi.org/10.1177/1934578x1000500412.

Full text

Abstract:

An HPLC method with reflux as an efficient extraction method has been developed for quantification of chromones in Dysophylla stellata Benth. Separation was achieved on a C18 column with a mobile phase of 0.5% (v/v) acetic acid in water (A), and ACN (B) under gradient elution at 1 mL/min. Chromones (1 and 2) isolated from D. stellata were used as standards for method development and validation was achieved according to ICH guidelines. Extracts prepared by three different methods [reflux, ultrasonication and accelerated solvent extraction (ASE)] were used for analysis by the validated method. T

APA, Harvard, Vancouver, ISO, and other styles

40

Satish, C. Gupta, and C. Kamboj Ramesh. "Photochemical transformations of chromones." Journal of Indian Chemical Society Vol. 80, Nov 2003 (2003): 1007–14. https://doi.org/10.5281/zenodo.5839680.

Full text

Abstract:

Department of Chemistry, Kurukshetra University, Kurukshetra-136 119<strong>, </strong>India <em>E-mail : </em>scguptaku@rediffmail.com <em>Manuscript received 2 September 2003</em> The photochemical transformations occurring in the chromones through cycloadditions, oxidations and reorganizations have been reviewed.

APA, Harvard, Vancouver, ISO, and other styles

41

Urbagarova, Bayarma Munhoevna, Vasiliy Vladimirovich Taraskin, Tat'yana Valer'yevna Elisafenko, El'vira Eduardovna Shults, Elena Anatol'yevna Korolyuk, and Лариса Доржиевна Radnaeva. "QUANTITATIVE CONTENT OF THE MAIN ACTIVE SUBSTANCES IN THE ROOTS OF THE NATURAL AND IN-TRODUCED PLANT SAPOSHNIKOVIA DIVARICATE (TURCZ.) SCHISCHK." chemistry of plant raw material, no. 3 (September 27, 2021): 143–51. http://dx.doi.org/10.14258/jcprm.2021039152.

Full text

Abstract:

A HPLC-UV method was developed for the quantitative analysis of chromones in the roots of Saposhnikovia divaricata (Turcz.) Schischk. The optimal parameters of chromones extraction (two-fold ultrasonic extraction with a duration of 40 min with 50% ethyl alcohol at a raw material-extractant ratio of 1:10) were selected. The validation analysis showed that the proposed method is characterized by satisfactory metrological parameters. The method was used for the analysis of raw materials of wild, introduced and commercial samples of S. divaricata. In this work, for the first time in the roots of S

APA, Harvard, Vancouver, ISO, and other styles

42

Hishmat, O. H., N. M. Fawzy, D. S. Farrag, and A. S. Abd El-All. "ChemInform Abstract: Aminolysis and Hydrolysis of Chromonyl Oxazolones Leading to New Chromones." ChemInform 31, no. 25 (2010): no. http://dx.doi.org/10.1002/chin.200025148.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Yang, Pei-Song, Jia-Meng Dai, Xue-Jiao Gu, et al. "Indole Alkaloids and Chromones from the Stem Bark of Cassia alata and Their Antiviral Activities." Molecules 27, no. 10 (2022): 3129. http://dx.doi.org/10.3390/molecules27103129.

Full text

Abstract:

The Cassia (Leguminosae) genus has attracted a lot of attention as a prolific source of alkaloids and chromones with diverse structures and biological properties. The aim of this study is to screen the antiviral compounds from Cassia alata. The extract of the stem bark of this plant was separated using silica gel, MCI, ODS C18, and Sephadex LH-20 column chromatography, as well as semi-preparative HPLC. As a result, three new indole alkaloids, alataindoleins A–C (1–3); one new chromone, alatachromone A (4); and a new dimeric chromone-indole alkaloid, alataindolein D (5) were isolated. Their str

APA, Harvard, Vancouver, ISO, and other styles

44

Patonay, Tamás, Attila Vasas, Attila Kiss-Szikszai, Artur M. S. Silva, and José A. S. Cavaleiro. "Efficient Synthesis of Chromones with Alkenyl Functionalities by the Heck Reaction." Australian Journal of Chemistry 63, no. 11 (2010): 1582. http://dx.doi.org/10.1071/ch10295.

Full text

Abstract:

The usefulness of the Heck reaction in the field of chromones has been demonstrated. Bromochromones with the halogen atom in their rings A and B were reacted with various terminal alkenes to give hitherto unknown alkenyl‐substituted chromones. Reactivity of the substrates was found to markedly depend on the position of the bromine atom. Under phosphine‐free conditions using a phase‐transfer catalyst additive (tetrabutylammonium bromide), shorter reaction periods and usually higher yields were obtained.

APA, Harvard, Vancouver, ISO, and other styles

45

Saengchantara, S. T., and T. W. Wallace. "Chromanols, chromanones, and chromones." Natural Product Reports 3 (1986): 465. http://dx.doi.org/10.1039/np9860300465.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Campos, Angela Martha, Duc Do Khac, and Marcel Fetizon. "Chromones from Dictyoloma incanescens." Phytochemistry 26, no. 10 (1987): 2819–23. http://dx.doi.org/10.1016/s0031-9422(00)83597-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Muñoz-López, F. "¿Réquiem por las chromones?" Allergologia et Immunopathologia 30, no. 2 (2002): 55–56. http://dx.doi.org/10.1016/s0301-0546(02)79090-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Baba, Kimiye, Hiromu Kawanishi, Masahiko Taniguchi, and Mitsugi Kozawa. "Chromones from Cnidium monnieri." Phytochemistry 31, no. 4 (1992): 1367–70. http://dx.doi.org/10.1016/0031-9422(92)80292-m.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Tanaka, T. "Chromones from Harrisonia perforata." Phytochemistry 40, no. 6 (1995): 1787–90. http://dx.doi.org/10.1016/0031-9422(95)00472-j.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Jin, Can, Xun Zhang, Bin Sun, Zhiyang Yan, and Tengwei Xu. "Iron-Catalyzed Regioselective Decarboxylative Alkylation of Coumarins and Chromones with Alkyl Diacyl Peroxides." Synlett 30, no. 13 (2019): 1585–91. http://dx.doi.org/10.1055/s-0037-1611864.

Full text

Abstract:

A facile iron-catalyzed decarboxylative radical coupling of alkyl diacyl peroxides with coumarins or chromones has been developed, affording a highly efficient approach to synthesize a variety of α-alkylated coumarins and β-alkylated chromones. The reaction proceeded smoothly without adding any ligand or additive and provided the corresponding products containing a wide scope of functional groups in moderate to excellent yields. This protocol was highlighted by its high regioselectivity, readily available starting materials, and operational simplicity.

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!