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Dissertations / Theses on the topic 'Chromonyl'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Riemer, Martin. "Vom Phenol zum Naturstoff : Entwicklung nachhaltiger Mikrowellen-vermittelter SUZUKI-MIYAURA-Kupplungen und Tandem-Reaktionen." Phd thesis, Universität Potsdam, 2014. http://opus.kobv.de/ubp/texte_eingeschraenkt_verlag/2015/7252/.

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Ziel dieser Arbeit war die Entwicklung von Methoden zur Synthese von auf Phenol basierenden Naturstoffen. Insbesondere wurde bei der Methodenentwicklung die Nachhaltigkeit in den Vordergrund gerückt. Dies bedeutet, dass durch die Zusammenfassung mehrerer Syntheseschritte zu einem (Tandem-Reaktion) beispielsweise unnötige Reaktionsschritte vermieden werden sollten. Ferner sollten im Sinne der Nachhaltigkeit möglichst ungiftige Reagenzien und Lösungmittel verwendet werden, ebenso wie mehrfach wiederverwertbare Katalysatoren zum Einsatz kommen. Im Rahmen dieser Arbeit wurden Methoden zum Aufbau

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2

Sabbagh, Liezel Veronica. "Chemical studies of chromone derivatives." Thesis, Rhodes University, 2001. http://hdl.handle.net/10962/d1006899.

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This study has focussed on several aspects of chromone chemistry, viz., (i) the influence of remote substituents on the basicity of 2-(N,N-dimethylamino)chromones, (ii) MoritaBaylis-Hillman reactions of substituted chromone-3-carbaldehydes and (iii) an investigation into the application of chromone chemistry in the total synthesis of the marine natural product, Rietone A. Selected 2-(N,N-dimethylamino )chromones were prepared using two different methods; firstly, via cyclisation of salicylate-derived N,N-dimethyl-3;.(2-hydroxyphenyl)-3- oxopropanamide precursors and, secondly, via 2-hydroxyace

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3

Alder, Paul Thomas. "Thin chromonic liquid crystal polymer films." Thesis, University of Leeds, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.291326.

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4

Hoffmann, Thomas. "Modifizierte Flavonoide als neuartige UVA-Schutzmittel Synthese, Untersuchungen zur Photostabilität und zum Singulett-Sauerstoff-Quenchverhalten /." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=971538832.

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5

Nchinda, Aloysius Tchangwe. "Chemical studies of selected chromone derivatives." Thesis, Rhodes University, 2002. http://hdl.handle.net/10962/d1007442.

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This investigation has been geared towards several aspects of chromone chemistry. Selected 2-(N,N-dimethylarnino)chromones have been synthesized via 2-hydroxyacetophenone boron difluoride complex intermediates, and potentiometric analysis of these compounds in ethanolwater has been used to determine the influence of substituents on their basicity. The pKa values have been found to lie within a narrow range (1.92 - 2.52), and the observed substituent effects have been rationalized with the aid of semi-empirical and ab initio molecular orbital calculations. An efficient route has been developed

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6

Liu, Hui. "Optical Characterization of Lyotropic Chromonic Liquid Crystals." Kent State University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=kent1153943609.

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7

Kreuzer, Anton Werner. "Die neonatale X-chromosal vererbte zentronukleare Myopathie /." [S.l : s.n.], 1987. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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8

Khan, R. A. "Synthesis of naturally occuring chromones and quinones." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1992. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3015.

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9

Davidson, Deborah Nicole. "Chemical and spectroscopic studies of chromone derivatives." Thesis, Rhodes University, 1992. http://hdl.handle.net/10962/d1006857.

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Various chromone derivatives have been used in asthma therapy, and their biological activity is apparently related to certain chemical features which include conformation and acidity. In the present study, substituent effects on conformation and acidity have been explored in chromone systems with potential biological activity. A range of variously substituted symmetrical chromone-2-carboxamides (including a series of N,N-dimethylchromone-2-carboxamides) have been prepared via chromone-2-carboxylic acids, which, in turn, were prepared from the corresponding o-hydroxyacetophenones. The N,N-dimet

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10

Ramaite, Ipfani David Isaiah. "Chemical and spectroscopic studies of chromone derivatives." Thesis, Rhodes University, 1993. http://hdl.handle.net/10962/d1006888.

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A number of biologically active chromones occur in plants (eg. Khellin) and research in this field has eventually led to the discovery of chromoglycic acid, which is widely used as a sodium salt in asthma therapy. Since biological activity may be related to acidity, a range of chromone-2-carboxylic acids have been prepared via Claisen acylation of substituted o- hydroxyacetophenones and their acid dissociation constants determined potentiometrically to explore substituent effects. From this study it has been found that introduction of certain groups does have a marked effect on acidity. A vari

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11

Hodges, Matthew David. "Physical mapping of chromosal rearrangements in Beckwith-Wieddemann syndrome." Thesis, Imperial College London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313712.

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12

Thind, Romnik. "Molecular simulation studies of chromonic mesogens in aqueous solution." Thesis, Durham University, 2018. http://etheses.dur.ac.uk/12467/.

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This thesis focuses on understanding the aggregation behaviour of lyotropic chromonic liquid crystals in aqueous solution. Molecular simulation methods are used to provide structural and thermodynamic information on the self-assembly of chromonic mesogens, and the results used to re-interpret data from previous experimental studies of these systems. Extensive atomistic level molecular dynamic simulations have been performed on three chromonic dyes in solution: 5,5'-dimethyoxy-bis-(3,3'-di-sulphopropyl)- thiacyanine triethylammonium salt (Dye A), 5,5'-dichloro-bis-(3,3'-di-sulphopropyl)- thiacy

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13

Clarke, P. D. "Transformation and addition reactions in the chromone series." Thesis, University of Salford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.372132.

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14

Ramaite, Ipfani David Isaiah. "Synthetic and physical organic studies of chromone derivatives." Thesis, Rhodes University, 1997. http://hdl.handle.net/10962/d1005045.

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A range of chromone-2-carboxylic acids has been prepared by condensing suitably substituted 2-hydroxyacetophenones with diethyl oxalate. pK₂ Studies of these acids revealed that 6- or 7-methoxy substituents decreased acidity while the 6-nitro group enhanced acidity; the strongest acid was the 3-chloro derivative, the increase in acidity being attributed to steric inhibition of acid-weakening delocalisation between the carboxyl group and the chromone system. Various chromone-2-carboxamides, derived from acid chloride precursors, were converted to polysubstituted acrylamides by nucleophilic ring

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15

Stockley, Martin Lee. "Design and synthesis of selective DNA-dependent protein kinase (DNA-PK) inhibitors." Thesis, University of Newcastle Upon Tyne, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369816.

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16

Agostinho, Daniel. "Investigation Phytochimique de plantes utilisées en médecine traditionnelle au Mozambique : Ptaeroxylon obliquum Radlk - Pyrenacantha kaurabassana Baill - Monadenium lugardae N.EBr." Thesis, Tours, 2013. http://www.theses.fr/2013TOUR3802/document.

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Les travaux menés dans cette thèse s’inscrivent dans une démarche ethno-pharmacologique visant à valoriser des plantes utilisées traditionnellement en médecine au Mozambique. Cette étude a comme but principal d’apporter des éléments chimio taxonomiques concernant des espèces végétales peu décrites et de préciser la composition métabolique de parties de plante utilisées en médecine traditionnelle, pour aboutir potentiellement à de nouvelles molécules utilisables en thérapeutique. Le travail est ainsi découpé en trois parties distinctes, chacune portant sur une plante différente.La Partie 1prése

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17

Wootton, R. C. R. "Synthetic approaches to polyoxygenated chromone and chromanome natural products." Thesis, University of Salford, 2000. http://usir.salford.ac.uk/2171/.

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The work described in this thesis is concerned with the chemistry of polymethoxylated aromatic carbonyl compounds bearing a 2,6-dioxygenated substitution pattern, with particular regard to establishing synthetic routes to biologically active chromone and chromanone systems. Syntheses of key intermediates in the approaches to the natural products stigmatellin, baicalein and LL-D253(x) (and related products) were undertaken. In chapter one the reactions of nucleophiles at the carbonyl moieties of 2,6- dioxygenated benzene carbonyl compounds are reviewed. This type of process can present special

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18

Ormerod, Andrew Paul. "The formation of chromonic liquid crystals by water-soluble azo-dyes." Thesis, University of Salford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261917.

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19

Priego, Moreno Sara. "Investigating the roles of ubiquitin and SUMO during eukaryotic chromosal replication." Thesis, University of Birmingham, 2017. http://etheses.bham.ac.uk//id/eprint/7820/.

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Genome duplication is an essential cellular process and its appropriate execution is required to maintain genome integrity. Ubiquitin and SUMO belong to the protein family of ubiquitin-like modifiers, and they are required to maintain genome integrity by acting as key regulators in the response to DNA damage. However, their role in the regulation of unperturbed DNA replication is less understood. My PhD work has focused on studying the roles of ubiquitin and SUMO during unperturbed DNA replication in Xenopus laevis egg extract. Members of our lab showed that polyubiquitylation of Mcm7 – a subu

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20

Yao, Xuxia. "Studies on lyotropic chromonic liquid crystals in nematic and biphasic regions." Diss., Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/50131.

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Chromonic liquid crystals are a relatively new class of lyotropic liquid crystals. In an effort to understand this lyotropic phase better, studies on the phase behavior, defects formed in these systems and characterization of the order were performed. We studied three chromonic liquid crystal materials in nematic and biphasic regions: Sunset Yellow FCF (SSY, a food dye), a cationic perylene diimide derivative (PDI, a conducting dye) and cromolyn sodium (DSCG, a drug). For SSY chromonics in the nematic region, order parameters ( and ) were obtained by polarized Raman measurements. Using the ord

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21

Alaoui, Moulay Ali. "Synthèses et études pharmacologiques d'indolyl-chalcones, chromones, chromanones, quinolones et dérivés." Paris 11, 1990. http://www.theses.fr/1990PA114837.

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22

Joshi, Leela Pradhan. "X-RAY STUDY OF MESOMORPHISM OF BENT-CORE AND CHROMONIC MESOGENS." Kent State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=kent1239979869.

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23

Ostapenko, Tanya. "Magneto-optical and Imaging Studies of Chromonic and Thermotropic Liquid Crystals." Kent State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=kent1319704652.

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24

Zhou, Shuang. "LYOTROPIC CHROMONIC LIQUID CRYSTALS: FROM VISCOELASTIC PROPERTIES TO LIVING LIQUID CRYSTALS." Kent State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=kent1460397447.

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25

Toullec, Anne. "Synthesis of chromones and flavones derivatives for pharmaceutical and cosmetical applications." Université Louis Pasteur (Strasbourg) (1971-2008), 2006. http://www.theses.fr/2006STR13238.

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Les flavonoïdes sont des composés polyphénoliques naturels largement distribués dans de nombreuses plantes. La plupart d’entre eux possèdent des activités biologiques (piégeurs de radicaux, anti-inflammatoires…), très recherchées dans l’industrie pharmaceutique et cosmétique. Les chromones sont des composés structurellement proches des flavones, beaucoup moins diversifiés dans la nature et dont les activités biologiques ont été moins étudiées que celles des flavones. Nous nous sommes intéressés, dans une première partie, aux activités cosmétiques et plus particulièrement dermatologiques de cer

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26

Park, Heung-Shik. "Self-assembly of lyotropic chromonic liquid crystals: Effects of additives and applications." Kent State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=kent1291043533.

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27

Swinford, Brown Roger. "The devlopment of new synthetic methods for chromone and ergochrome construction." Thesis, University of Southampton, 1986. https://eprints.soton.ac.uk/192477/.

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The ergochromes possess useful anti-tumour properties whilst chromones are useful drugs for the treatment of allergic asthma. The aim of the project was to synthesise ergoflavin or an analogue for the first time, and to this end novel synthetic methods for a, 6-unsaturated ketones and oxygenated dienes were developed. Two major routes are described: The first uses aliphatic starting materials and allows the construction of highly substituted chromones by an intramolecular Diels-Alder reaction. To achieve this a synthetic method to novel phenylthio substituted 3-unsaturated ketone equivalents (

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28

Pintiala, Catalin. "Valorisation des chromones dans la synthèse de nouveaux systèmes polyhétérocycliques à activités anticancéreuses." Thesis, Le Havre, 2014. http://www.theses.fr/2014LEHA0006.

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Ce travail de thèse décrit la synthèse, la réactivité et les propriétés biologiques des dérivés 2-pyridoniques obtenus à partir de substrats simples appartenant à la famille des chromones. Lors de ce projet, les énaminochromanones - représentant une nouvelle classe d’hétérocycles - ont été identifiées comme étant des intermédiaires cinétiques stables et facilement isolables. Certains composés de type pyridin-2-one ont été diversifiés et, parmi les produits synthétisés, certains ont montré des activités anticancéreuses via inhibition du processus de transition épithélio-mésenchymateuse (TEM). U

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29

Murphy, A. J. "Absorption, distribution and elimination of sodium chromoglycate and other chromones studied by autoradiography." Thesis, Nottingham Trent University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236907.

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30

Molefe, Duduzile Mabel. "Studies directed towards the synthesis of chromone carbaldehyde-derived HIV-1 protease inhibitors." Thesis, Rhodes University, 2008. http://hdl.handle.net/10962/d1015542.

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A series of chromone-3-carbaldehydes have been prepared using Vilsmeier-Haack methodology while a corresponding series of chromone-2-carbaldeydes have been synthesized via the Kostanecki-Robinson reaction. Baylis-Hillman reactions have been conducted on both series of chromone carbaldehydes using three different catalysts, viz., 1,4-diazabicyclo(2.2.2]octane (DABCO), 1,8-diazabicyclo[5.4.0]undec- 7-ene (DBU) and 3-hydroxyquinuclidine (3HQ), and acrylonitrile, methyl acrylate and methyl vinyl ketone as the activated alkenes. These reactions have typically (but not always!) afforded both normal

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31

Alves, Iura Muniz. "Estudo fitoquímico da raiz de Dictyoloma vandellianum A. Juss." Instituto de Química, 2008. http://repositorio.ufba.br/ri/handle/ri/20246.

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Submitted by Ana Hilda Fonseca (anahilda@ufba.br) on 2016-08-31T15:49:34Z No. of bitstreams: 1 Estudo fitoquímico da raiz de Dictyoloma vandellianum A. Jus.pdf: 13732713 bytes, checksum: 433553ed8ebe16e3ce80d35862057ca6 (MD5)<br>Approved for entry into archive by Vanessa Reis (vanessa.jamile@ufba.br) on 2016-09-02T16:23:25Z (GMT) No. of bitstreams: 1 Estudo fitoquímico da raiz de Dictyoloma vandellianum A. Jus.pdf: 13732713 bytes, checksum: 433553ed8ebe16e3ce80d35862057ca6 (MD5)<br>Made available in DSpace on 2016-09-02T16:23:26Z (GMT). No. of bitstreams: 1 Estudo fitoquímico da raiz de Di

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32

Neupane, Krishna Prasad. "Light Scattering Studies of Orientational Order in Liquid Crystalline Tetrapodes and Lyotropic Chromonic Liquid Crystals." Kent State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=kent1239811255.

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33

Ives, David. "Assessing the Impact of Genetically Modified Canola Cultivars on the Biology of Soil." Thesis, Griffith University, 2017. http://hdl.handle.net/10072/370734.

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Biotechnological development of transgenic crops and widespread international adoption has stimulated comprehensive research into their effects on the soil environment. Insects (both target and non-target), weeds, aquatic environments, and soils have all been extensively researched. Since the first commercial GM crop in 1995, the debate surrounding controversial aspects of their biology has polarised issues concerning insects, weeds, and the concentration of technology within a few multinational biotechnology corporations. The effect of transgenic crops on the biology of soils seemed to attrac

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34

Rossollin, Valérie. "Systèmes photochromiques prototropiques et électrocycliques en séries chromone et thiochromone : synthèse, caractérisation et étude spectrocinétique." Aix-Marseille 2, 2001. http://www.theses.fr/2001AIX22040.

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35

Skowyra, Agnieszka. "Using a tryptophan-regulated promoter system to study chromosal DNA replication in archaeal model organism Haloferax volcanii." Thesis, University of St Andrews, 2013. http://hdl.handle.net/10023/3620.

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Chromosomal DNA replication is an essential process for all forms of cellular life. Archaea, the third domain of life, possess a DNA replication apparatus that shares significant protein sequence similarity with eukaryotic replication factors, making the Archaea a good model system for understanding the biology of chromosome replication in Eukaryotes. The results described in this thesis contribute to the genetic and physiological characterisation of DNA replication in the model organism Haloferax volcanii, a halophilic euryarchaeon. The thesis documents the generation of conditional lethal mu

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36

Muddala, Ramesh, and Ramesh Muddala. "Synthèse de buténolides naturels et développement d'une nouvelle réaction en cascade pour l'élaboration de furo (2,3-b) chromones." Doctoral thesis, Université Laval, 2018. http://hdl.handle.net/20.500.11794/37672.

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Cette thèse décrit le développement d’une nouvelle méthode de synthèse et l’établissement de plusieurs synthèses totales de produits naturels poly-oxygénés d’intérêt biologique et médicinal. En particulier, nous décrirons la première synthèse de l’antibiotique antitumoral basidalin comportant une structure unique (chapitre 2). Originalement isolé d’une éponge terrestre en 1983, basidalin est le seul et unique produit naturel possédant un motif tétronamide. De plus, il a démontré des activités antitumorales in vitro et in vivo significatives. Ces attributs ont attiré l’attention des communautés

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37

GLOANEC, PHILIPPE. "Utilisation de la reaction de wittig pour la synthese de chromones polysubstituees : application a des composes d'interet pharmacologiques." Rennes 1, 1993. http://www.theses.fr/1993REN10050.

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Le travail presente dans ce memoire nous a permis d'elargir le domaine d'application de la condensation de wittig a la synthese de chromones polysubstituees et de mettre en evidence les limites de cette reaction. L'etude de la cyclisation, realisee dans la premiere partie, a permis de mettre en evidence le role fondamental joue par les facteurs steriques dans la competition entre le processus de cyclisation menant a la chromone et la reaction concurrente qui conduit a un arylalcyne. L'obtention de la chromone est la voie la plus courante, l'acetylenique ne se forme de maniere significative que

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38

Bhandare, Richie R. "Investigation into the bioisosteric approach in the design, synthesis and evaluation of muscarinic receptor ligands." Diss., Temple University Libraries, 2013. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/214985.

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Pharmaceutical Sciences<br>Ph.D.<br>The acetylcholine (ACh) receptor system belongs to rhodopsin GPCR family and is an integral membrane protein divided into two types: muscarinic and nicotinic. The naturally occurring neurotransmitter acetylcholine binds to these two receptor systems non- selectively. The regulatory effects of the neurotransmitter acetylcholine are diverse ranging from autonomic nervous system and the central nervous system through different types of neurons innervated by cholinergic inputs. Muscarinic acetylcholine receptors (mAChRs) are divided into five receptor subtypes (

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Bhandare, Richie R. "Thesis-Final-supplementary." Diss., Temple University Libraries, 2013. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/215231.

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Pharmaceutical Sciences<br>Ph.D.<br>The acetylcholine (ACh) receptor system belongs to rhodopsin GPCR family and is an integral membrane protein divided into two types: muscarinic and nicotinic. The naturally occurring neurotransmitter acetylcholine binds to these two receptor systems non- selectively. The regulatory effects of the neurotransmitter acetylcholine are diverse ranging from autonomic nervous system and the central nervous system through different types of neurons innervated by cholinergic inputs. Muscarinic acetylcholine receptors (mAChRs) are divided into five receptor subtypes (

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40

Picot, Claudia. "Le "Ledebouriella sesloides" et le "Glehnia littoralis"." Paris 5, 1996. http://www.theses.fr/1996PA05P052.

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41

Goma, Jean Richard. "Applications de l'alkylation catalysée par transfert de phase dans la synthèse de coumarines, de chromones, d'amides et de photoxyéthers d'intérêt thérapeutique." Paris 11, 1989. http://www.theses.fr/1989PA114820.

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42

Joussot, Jessie. "Stratégies de synthèse d’un nouvel antipsychotique potentiel : cascades réactionnelles palladocatalysées : un outil puissant pour la synthèse de structures polycycliques complexes et hautement fonctionnalisées." Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAF016/document.

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Ces travaux de thèse ont permis dans un premier temps, d'aborder différentes voies de synthèse d'un nouvel antipsychotique potentiel (F17464) proposé par les laboratoires Pierre Fabre. Trois stratégies basées sur des synthèses convergentes ont été initiées. La première stratégie repose sur une étape clé de métathèse croisée, la seconde sur une réaction de Sonogashira et la troisième aborde une nouvelle méthodologie d'alkylation des chromones en position 3. Ces méthodes nous ont permis d'accéder à des intermédiaires de synthèse originaux, utiles pour préparer la molécule F17464 en respectant le

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43

Macklin, Todd Kristopher. "The development of sulfamates as latent directed metalation groups. Total synthesis of schumanniophytine. Divergent synthesis of substituted chromone 3- and 8-carboxamides." Thesis, Kingston, Ont. : [s.n.], 2007. http://hdl.handle.net/1974/925.

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44

Mujahid, M. "Asymmetric syntheses of pharmaceutically important compounds employing hydrolytic kinetic resolution strategy and development of novel chromone based derivatives as potent antitubercular agents." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2013. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2196.

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45

Zwergel, Clemens. "Synthesis and biological evaluation of various heterocyclic compounds : Aurones from Coumarins and Chromones, Quinolines and Pyrimidines as DNMTi, Coumarins as potential NF-kB inhibitors." Thesis, Université de Lorraine, 2013. http://www.theses.fr/2013LORR0276/document.

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Aujourd'hui, le cancer est devenu un problème majeur de santé publique avec 12,7 millions de nouveaux cas de cancer et 7,6 millions de décès enregistrés en 2008. Même si le nombre des personnes qui guérissent augmente, les décès sont toujours importants. Les raisons, malgré un diagnostic précoce et correct, sont l'absence de traitements efficaces et l'émergence des résistances à la thérapie anticancéreuse. C'est pourquoi les chercheurs s'intéressent aux nouvelles approches pour développer des traitements puissants et sélectifs pour vaincre le cancer. Dans notre première approche, nous avons dé

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46

Bergquist, Leah Elaine. "Chirality in liquid crystals - from bent-cores to chromonics." Kent State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=kent1511897907175184.

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47

Letulle, Cécile. "Synthèse et vectοrisatiοn de nοuvelles chalcοnes et dérivés à activité anticancéreuse". Electronic Thesis or Diss., Normandie, 2024. http://www.theses.fr/2024NORMLH37.

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Les chalcones sont des molécules naturelles douées d’une myriade d’activités biologiques parmi lesquelles l’activité anticancéreuse. Dans cette thèse, une large bibliothèque de chalcones, portant une diversité au niveau du noyau B tout en conservant le noyau A 3,4,5-triméthoxylé important pour l’effet antiprolifératif, a été synthétisée. Cette bibliothèque a été obtenue grâce à la condensation de Claisen-Schmidt entre un réactif de départ commun, la 3,4,5- triméthoxyacétophénone, et les aldéhydes appropriés. Les composés synthétisés ont été évalués pour leur activité antiproliférative contre l

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Queiroga, Cinthia Silveira. "Novas substâncias isoladas de Evolvulus linarioides Meisn. (Convolvulaceae)." Universidade Federal da Paraíba, 2012. http://tede.biblioteca.ufpb.br:8080/handle/tede/6757.

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Made available in DSpace on 2015-05-14T12:59:44Z (GMT). No. of bitstreams: 1 ArquivoTotal.pdf: 3688068 bytes, checksum: 2a796c235bc859cfcc93483db6d3f202 (MD5) Previous issue date: 2012-04-25<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>The Caatinga biome is a promising source of biomolecules of plant origin. In Paraíba, Northern Brazil, the Pico do Jabre state park is the largest area of total protection and conservation included in this biome, where is possible to find the species Evolvulus linarioides Meisn, a small blue-flowered herb, distributed at lower

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Obah, kosso Anne. "Arylsélénation et sélénocyanation d'hétérocycles riches en électrons." Electronic Thesis or Diss., Aix-Marseille, 2019. http://www.theses.fr/2019AIXM0643.

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Ce travail s’inscrit dans la recherche et le développement de nouvelles méthodologies pour la synthèse de molécules portant un groupement sélénocyané ou arylsélanyle. Dans une première partie, le trisélénodicyanure (TSD) généré à partir du malononitrile et du dioxyde de sélénium a été utilisé pour la substitution électrophile d’hétérocycles riches en électrons tels que les imidazohétérocycles, les chromèn-4-ones et également pour l’ipso-sélénocyanation d’acides arylboroniques sans l’utilisation de métaux. Cette sélénocyanation permet d’accéder rapidement et de façon fiable aux dimères diséléni

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Campos, Angela Martha. "Les polyphénols naturels du Dictyoloma incanescens (Rutacées) et du Diplopanax stachyanthus (Araliacées)." Paris 11, 1988. http://www.theses.fr/1988PA112293.

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Cette thèse comprend deux parties :Première Partie : Polyphénols naturels du dictyoloma incanescens (Rutaeées)(Brésil). Les études chimiques et spectroscopiques (Masse, R. M. N. 1H et 13C) des écorces du dictyoloma incanescens ont permis d'isoler et d'identifier deux nouvelles chromones : la (méthyl-3-butényl-2)-6 allopteroxyline et son éther méthylique. Polyphénols naturels du Diplopanax stachyanthus(Araliacées) (Viêt-Nam). De l'extrait méthanolique des écorces du Diplopanax stachyanthus ont été isolés deux nouveaux composés de la série de l'acide ellagique. Sous la forme de xyloside : l'acid

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