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Journal articles on the topic 'Chronic Apical Periodontiti'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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1

Da Silva, Kemilly Maria Santos, Ramon Brandino de Melo Nascimento, Yasmim Pinho Do Nascimento, et al. "Periodontite apical crônica: relato de caso / Chronic apical periodontitis: case report." Brazilian Journal of Development 8, no. 6 (2022): 43625–34. http://dx.doi.org/10.34117/bjdv8n6-073.

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2

Gheorghiu, Irina-Maria, Paula Perlea, Alexandru A. Iliescu, and Loredana Mitran. "The modern approach to the treatment of chronic apical periodontitis - review of literature." ORL.ro 2, no. 1 (2016): 30–33. http://dx.doi.org/10.26416/orl.31.2.2016.136.

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This paper reviews the literature on the current concept of the treatment of chronic apical periodontitis. This is an important issue because without adequate endodontic treatment, the infection of the root canal and periradicular tissue may result in loss of supporting apical periodontium and increases the possibility of tooth extraction.
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3

Sutasmi, Yeyen, and Nurhayati Natsir. "Identifikasi bakteri pada saluran akar gigi dengan diagnosis periodontitis apikalis kronis (Identification of bacteria in dental root canal diagnosed with chronic apicalis periodontitis)." Journal of Dentomaxillofacial Science 13, no. 3 (2014): 182. http://dx.doi.org/10.15562/jdmfs.v13i3.412.

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Chronic apical periodontitis is one of common periapical diseases. Inflammation in the periapical tissue is caused bybacteria from the root canal necrotic. If the tooth is not treated, the infection can progress to periapical region causingchronic apical periodontitis. The variety of bacteria can be found in root canal with chronic apical periodontitis. Thisstudy aims to determine the type of bacteria in chronic apical periodontitis. Samples were obtained from fifteen patientswith teeth that have chronic apical periodontitis in the Department of Conservative Dentistry in Dental Hospital ofHasa
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4

Юсупова, Алина, Alina Yusupova, Лариса Герасимова, et al. "MONITORING OF THE MICROCIRCULATION OF THE MUCOUS MEMBRANE CONDITION IN THE TRANSITORY FOLD OF TEETH WITH CHRONIC APICAL PERIODONTITIS IN THE DYNAMICS OF COMPLEX ENDODONTIC TREATMENT." Actual problems in dentistry 15, no. 3 (2019): 75–81. http://dx.doi.org/10.18481/2077-7566-2019-15-3-75-81.

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Subject. A sufficiently sensitive, high-resolution method of laser doppler flowmetry is used to characterize the сlaudication in the oral mucous membrane and periodontal tissues. This method makes it possible to detect early changes in the microcirculatory bloodstream and predict the course of chronic apical periodontitis. With the help of the method of laser doppler fluorometry, a comparative monitoring of the microcirculatory bloodstream of the mucous membrane of the transitory fold in the area of intact teeth and teeth with chronic apical periodontal was carried out. 
 The aim of this
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5

Bagryantseva, N. V. "The comorbid pathology in patients with chronic apical periodontitis." Medical alphabet, no. 18 (November 2, 2024): 73–77. http://dx.doi.org/10.33667/2078-5631-2024-18-73-77.

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The purpose of this study was to study the relationship between teeth after endodontic treatment and/or with apical periodontitis, in patients with a number of systemic diseases and smokers among the adult population of Yaroslavl.Materials and methods of research. Medical history data were collected, including age, gender, presence of cardiovascular diseases, diabetes mellitus, allergies, smoking habits and data on endodontic dental treatment of 421 patients (10,540 teeth). The prevalence of depulpated teeth and the periodontal condition were assessed by orthopantomograms. The periapical statu
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6

Khomich, S., B. Kritsky, and A. Khomich. "Morphological research of chronic apical periodontitis." International Journal of Oral and Maxillofacial Surgery 38, no. 5 (2009): 573. http://dx.doi.org/10.1016/j.ijom.2009.03.615.

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7

Karteva, Teodora, and Neshka Manchorova-Veleva. "The Role of the Immune Response in Chronic Marginal and Apical Periodontitis." Folia Medica 62, no. 2 (2020): 238–43. http://dx.doi.org/10.3897/folmed.62.e39599.

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The immune response is a complex, dynamic and strongly individual biologic network that plays an essential role in the pathogenesis of chronic apical and marginal periodontitis. Recent research in the field of periodontology has indicated that the major determinant of susceptibility to disease is the nature of the immunoinflammatory response as marginal periodontal tissue damage is thought to be primarily mediated by the host reaction. Whether the same rules apply for the development of apical periodontitis, however, remains largely unexplored. This review aims to draw parallels between the pa
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8

Pavlovich, O. A., L. A. Skorikova, N. P. Bazhenova, and N. V. Lapina. "OPTIMIZATION OF TREATMENT OF DESTRUCTIVE FORMS OF CHRONIC APICAL PERIODONTITIS." Russian Journal of Dentistry 21, no. 2 (2017): 85–89. http://dx.doi.org/10.18821/1728-28022017;21(2):85-89.

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Increase of efficiency of treatment of patients with chronic apical periodontitis is a priority in dentistry. A root canal is a breeding ground for microorganisms. The main reason for unfavourable treatment outcomes of teeth with chronic apical periodontitis is incomplete debridement of the root canal system. Optimizing the treatment of patients with chronic periodontitis with the use of complex drugs galodent No. 4 (clotrimazole, tracert and calcium hydroxide) is a priority in dentistry. As a result of researches it is established that the antibacterial effect of the temporary investment of c
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9

Moldoveanu, Georgiana Florentina, Ioana Suciu, and Paula Perlea. "Chronic apical periodontitis in chronic kidney disease patients." STOMATOLOGY EDU JOURNAL 3, no. 1-2 (2016): 28–32. http://dx.doi.org/10.25241/stomaeduj.2016.3(1-2).art.4.

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10

Ayoub, AA, and GSP Cheung. "Management of C-shaped canals using “Membrane-Barrier Technique”: A Case report." Compendium of Oral Science 9, no. 1 (2022): 80. http://dx.doi.org/10.24191/cos.v9i1.16912.

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A 61-year old Chinese female was referred from a general private practitioner for persistent buccal abscess after completion of root canal treatment of tooth 37. On clinical examination, tooth 37 presented with a metal-ceramic crown (CMC) with 2mm of gingival recession noted at the buccal region. The overlying amalgam core was overhanging on distal and grade 2 mobility. The 37 CMC have no contact point at the distal. Tooth 37 was not tender to palpation but tender to percussion. No periodontal pocketing was detected. The periapical radiograph revealed a periapical radiolucent area associated e
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11

Tillaevna, Shukurova Nodira. "Use of New Silers In the Treatment of Apical Periodontitis of Permanent Teeth." European International Journal of Multidisciplinary Research and Management Studies 05, no. 04 (2025): 84–87. https://doi.org/10.55640/eijmrms-05-04-19.

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To obtain clinical experience of using new silers in treatment of apical periodontitis of permanent teeth.Treatment of chronic apical periodontitis of permanent teeth with root canal obturation with new siler based on epoxy resin and bioceramic siler has been carried out.
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12

Куратов, Илья, Ilia Kuratov, Марина Нагаева, et al. "ANALYSIS OF THE CAUSES OF FAILURE OF ENDODONTIC TREATMENT AND THE CAUSES OF TOOTH EXTRACTION WITH A DIAGNOSIS OF CHRONIC APICAL PERIODONTITIS." Actual problems in dentistry 15, no. 1 (2019): 28–32. http://dx.doi.org/10.18481/2077-7566-2019-15-1-28-32.

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Object. Causes of failure of endodontic treatment and causes of tooth extraction with a diagnosis of chronic apical periodontitis. Purpose ― to analyze the causes of failure of endodontic treatment and the causes of tooth extraction with a diagnosis of chronic apical periodontitis to determine ways to improve the effectiveness of conservative treatment. Methodology. A retrospective analysis of 864 medical records of a dental patient and 532 results of x-ray examinations of patients who underwent tooth extraction was carried out. 198 dentists-therapists of the city of Tyumen and the South of th
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13

Ramos-Perez, Flávia Maria de Moraes, Ulysses Nicida Soares, Yara Teresinha Corrêa Silva-Sousa, and Danyel Elias da Cruz Perez. "Ossifying Fibroma Misdiagnosed as Chronic Apical Periodontitis." Journal of Endodontics 36, no. 3 (2010): 546–48. http://dx.doi.org/10.1016/j.joen.2009.11.027.

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14

Максимович, Е. В., and С. Ф. Кураленя. "Verification of Actinomycets in Chronic Apical Periodontitis." Стоматология. Эстетика. Инновации 7, no. 4 (2023): 438–43. http://dx.doi.org/10.34883/pi.2023.7.4.001.

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Актиномицеты являются естественными обитателями организма человека, в том числе и полости рта, однако они могут явиться причиной развития патологического процесса. Актиномикоз – это хроническое инфекционное заболевание, вызываемое актиномицетами, хроническая медленно прогрессирующая специфическая инфекция. Цель. Верифицировать актиномицеты при морфологическом исследовании грануляционной ткани у пациентов с хроническим апикальным периодонтитом. Материалы и методы. Предметом исследования являлся морфологический материал – грануляционная ткань, полученная в результате кюретажа лунки зуба, показан
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15

Yusupova, Alina, Larisa Gerasimova, Milyausha Kabirova, Irina Usmanova, and Irina Mashkina. "COMPARATIVE EVALUATION OF THE EFFECTIVENESS OF ENDODONTIC TREATMENT OF CHRONIC APICAL PERIODONTITIS." Actual problems in dentistry 15, no. 4 (2020): 72–79. http://dx.doi.org/10.18481/2077-7566-2019-15-4-72-79.

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Subject. One of the possible causes of the development of chronic apical periodontitis is the presence of facultative and obligate-anaerobic microflora, due to the vital activity of which there is a process of resorption of the periapical periodontal tissues and a violation of the microcirculation of the mucous membrane in the area of the transitional tooth fold with apical periodontitis, and modern endodontic treatment does not always contribute to them stabilization.
 The goal is a comparative study of the effectiveness of the impact of various methods of endodontic treatment of chronic
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16

Li, Xiujuan, Xuesong Han, Wenlei Yu, Xing Chen, Ying Wu та Linjie Lu. "Correlation between Transforming Growth Factor-β and Periapical Lesions in Patients with Chronic Apical Periodontitis". Journal of Healthcare Engineering 2022 (22 березня 2022): 1–7. http://dx.doi.org/10.1155/2022/2173434.

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Objective. To examine the expression of transforming growth factor-β (TGF-β) in the periapical granulation tissue and serum of patients with chronic apical periodontitis and to conduct immunohistochemical analysis so as to explore the relationship between TGF-β and the degree of periapical lesions. Methods. Periapical granulation tissues of 20 cases of chronic apical periodontitis were collected as the experimental group. Healthy gingival tissues without eruption of third molars of 5 cases were collected as the control group. Immunohistochemistry, enzyme-linked immunosorbent assay, and real-ti
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17

Moroz, P. I., A. K. Iordanishvili, V. A. Prohodnaya, S. Yu Maxyukov, A. V. Safronenko, and E. Sh Gulyaeva. "Features of clinical course and treatment principles of endodontic-periodontal lesions." Kazan medical journal 99, no. 3 (2018): 362–68. http://dx.doi.org/10.17816/kmj2018-362.

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Aim. To study the characteristic differences in the clinical course of chronic generalized periodontitis in the presence of periapical infection focus and the principles of combined treatment of endodontium and periodontium. Methods. A clinical and X-ray examination of 1525 patients of different age groups was performed. As a result, a clinical group of 68 patients with chronic generalized moderate and severe periodontitis was formed, who were divided into two groups depending on the presence or absence of periapical destruction. In group 1, 32 patients with the presence of chronic generalized
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18

Singhal, Rajnish K., and Balwant Rai. "Retracted: sTNF-R Levels: Apical Periodontitis Linked to Coronary Heart Disease." Open Access Macedonian Journal of Medical Sciences 5, no. 1 (2017): 68–71. http://dx.doi.org/10.3889/oamjms.2017.010.

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BACKGROUND: Different studies have implicated the exposure to systemic conditions in the aetiology of cardiovascular diseases like chronic inflammation including chronic periodontitis.
 AIM: The present study has been conducted to examine whether biomarker sTNF-R was elevated in apical periodontitis as sTNF-R is a systemic marker of inflammation and has been identified as risk factors for cardiovascular diseases.
 MATERIAL AND METHODS: sTNF-R levels were measured in 52 patients with apical periodontitis (M:F::25:27), aged 20-45 years and in 20 control patients without periodontitis (
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19

DEMYANENKO, SVETLANA A., MARINA N. MOROZOVA, NATALIA V. PAVLOVA, et al. "MICROBIOTA OF THE ROOT CANAL SYSTEM IN PATIENTS WITH DESTRUCTIVE FORMS OF CHRONIC APICAL PERIODONTITIS BEFORE AND AFTER STANDARD ENDODONTIC TREATMENT AND MODERN POSSIBILITIES OF INFLUENCING IT." Bulletin of Contemporary Clinical Medicine 15, no. 3 (2022): 15–20. http://dx.doi.org/10.20969/vskm.2024.15(3).15-20.

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Abstract. Introduction. Despite the modern achievements of endodontics, it is possible to obtain a positive effect in the treatment of destructive forms of chronic apical periodontitis in 80-85% of cases. In other patients, progressive pathology becomes the main cause of tooth loss with subsequent deformation of the dentition, changes in the temporomandibular joint, the development of purulent- inflammatory processes of the maxillofacial region or complicated course of somatic diseases. Aim. The aim of the study was to study the dynamics of microbiological parameters in patients with chronic a
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20

Vaziri, Farzane, Ahmad Haerian, Laleh Maleki, and Samane Abbasi. "Histological characteristics of dental pulp in teeth with periodontal problems and healthy teeth." Journal of Advanced Periodontology & Implant Dentistry 15, no. 1 (2022): 10–14. http://dx.doi.org/10.34172/japid.2023.005.

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Background. Chronic periodontitis is the most common type of periodontitis, which is associated with calculus and plaque accumulation. Several studies have indicated that uncured periodontitis can affect the dental pulp. However, this relationship is controversial. This study aimed to compare histopathological results obtained from the dental pulp in teeth with periodontal problems and healthy teeth. Methods. In this study, 23 teeth with periodontal problems and 23 healthy teeth were extracted. After cutting off 2 mm from the root apex, the teeth were sectioned into apical, middle, and coronal
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Berezin, K. A. "Prevalence and clinical variety of periodontitis in patients attending dental policlinics in Kazan, Russia." Kazan medical journal 94, no. 2 (2013): 198–201. http://dx.doi.org/10.17816/kmj1588.

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Aim. To determine different periodontal diseases prevalence and distribution in patients attending dental policlinics in Kazan, Russia. Methods. Clinical screening, computed statistical analysis were used as a study methods. 517 medical charts of dental patients (form 043/A) were randomly selected. Different forms of periodontitis were classified according to ICD-10. Results. A high prevalence of periodontal diseases reaching 100% was found among the examined patients who had attended dental policlinics in Kazan, Russia. Chronic (34-89%) and acute (11-44%) apical periodontitis were the most pr
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22

Sudimartini, Luh Made, Anastasia Bhala, I. Wayan Wirata, Ni Luh Eka Setiasih, Ni Kadek Eka Widiadnyani, and I. Made Merdana. "Kidney Histopathology of Wistar Rats Chronic Apical Periodontitis." Advances in Tropical Biodiversity and Environmental Sciences 6, no. 2 (2022): 50. http://dx.doi.org/10.24843/atbes.2022.v06.i02.p04.

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Chronic apical periodontitis is an inflammatory disease that causes periodontal tissue destruction and forms chronic lesions. This study aims to prove that the administration of green meniran leaf ethanol extract can affect the kidney histopathology of chronic apical periodontitis Wistar rats. This study used a randomized posttest only control group design with four treatment groups and twelve replications of three sub-groups according to the time of application of the medicament paste, namely the 7th, 14th, and 21st days so that 48 Wistar rats were used. The treatment group consisted of negat
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23

Travassos, Rosana Maria Coelho, William Wale Rodrigues Martins, Lucas Godoy Martins, et al. "CHRONIC APICAL PERIODONTITIS REPAIR: 2-YEAR FOLLOW-UP." Derecho y Cambio Social 21, no. 78 (2025): e55. https://doi.org/10.54899/dcs.v21i78.55.

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The present study aims to present the clinical case report regarding non-surgical endodontic treatment performed on tooth 37, with a circumscribed periapical lesion, suggesting a phoenix abscess. The methodology consists of an individual descriptive case report study, which includes radiographic images of a 15-year-old female patient. Clinically, in addition to swelling, it was found that there was mobility, absence of pain in the thermal test (cold) and on palpation. After a complete clinical examination, endodontic treatment, coronary opening, root canal exploration, and root canal preparati
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Korniichuk O. E. "THE EFFECTIVENESS OF USAGE TRIACORTUM, CLOTRIMAZOLE AND DOXYCYCLINE FOR CHRONIC APICAL PERIODONTITIS TREATMENT." World Science 3, no. 6(46) (2019): 18–21. http://dx.doi.org/10.31435/rsglobal_ws/30062019/6571.

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 This article represents the work for searching new and effective treatment modality for chronic forms of periodontitis with application of the antibiotic doxycycline, antifungal agent clotrimazole and glucocorticosteroid triacortum.It was made the clinical judgement of treatment of 150 patients with chronic apical periodontitis. It was indicated an improvement of microcirculation in periodontitis tissue by Lazer Doppler flowmetry method by those patients who received therapy using proposed method of treatment and set of medication.
 
 
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25

Irina-Maria, Gheorghiu, Mitran Loredana, Mitran Mihai, Temelcea Anca-Nicoleta, Scarlatescu Sanziana, and Perlea Paula. "Specific Aspects of Endodontic Medication in Chronic Apical Periodontitis." ARS Medica Tomitana 25, no. 3 (2019): 125–28. http://dx.doi.org/10.2478/arsm-2019-0025.

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Abstract This article presents specific aspects regarding the role of endodontic medication in the conservative treatment in chronic apical periodontitis. Starting from the bacterial microflora, the etiological factor of the periapical lesions, we discuss about the modalities of identification by the means of in vivo and in vitro tests of the microorganisms present inside the root canal. The characteristics of these methods of microbiological evaluations, as well as their clinical relevance, are reviewed. The general characteristics of endodontic antimicrobial medication are presented, as well
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26

Naglieri, Christopher M., Ellie Bash, Glen A. Karunanayake, Carlos H. R. Camargo, and Takashi Komabayashi. "Successful Non-Surgical Root Canal Treatment on Auto-Transplanted Maxillary Premolar with Apical Periodontitis." Case Reports in Dentistry 2023 (June 3, 2023): 1–7. http://dx.doi.org/10.1155/2023/9389760.

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Auto-transplantation is a procedure that replaces traumatized or congenitally missing teeth. While most auto-transplanted teeth are successfully integrated into recipient sites, the donor tooth may develop apical periodontitis, causing early failure. In the present case report, the periodontic resident performed the procedure on a 15-year-old male by selecting donor teeth #4 and #13 and transplanting them at recipient sites #29 and #20, respectively. After 6 weeks, the patient was referred to the endodontic resident for evaluation of tooth #20 due to symptom development. While one auto-transpl
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27

Siqueira Jr, José F., and Isabela N. Rôças. "Bacterial pathogenesis and mediators in apical periodontitis." Brazilian Dental Journal 18, no. 4 (2007): 267–80. http://dx.doi.org/10.1590/s0103-64402007000400001.

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Apical periodontitis is a group of inflammatory diseases caused by microorganisms (mainly bacteria) infecting the necrotic root canal system. The pathogenesis of different types of apical periodontitis and even the same type in different individuals is unlikely to follow a stereotyped fashion with regard to the involved bacterial mediators. Disease pathogenesis is rather complex and involves a multitude of bacteria- and host-related factors. This review article discusses the bacterial pathogenesis of acute and chronic apical periodontitis, with the main focus on the bacterial mediators conceiv
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Loza, K., and S. Boitsaniuk. "ENDODONTIC PERIAPICAL LESION: AN OVERVIEW ON THE ETIOLOGY, DIAGNOSIS AND CURRENT TREATMENT MODALITIES." Scientific heritage, no. 114 (June 9, 2023): 22–24. https://doi.org/10.5281/zenodo.8019711.

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Chronic periapical periodontitis (CAP) is a typical oral disease in which periodontal inflammation caused by an odontogenic infection eventually leads to bone loss. Despite substantial progresses of modern endodontics with regards to mechanical instrumentation of radicular spaces, root canal infections, and their associated apical periodontitis lesions remain remarkably prevalent. Knowledge of microbial location, organisation and virulence factors within the root canal system is important for understanding the disease process.
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Chandran, Anu, Anegundi Raghavendra Vamsi, Biju Thomas, and Sreelatha S. V. "Radicular cyst as an epilogue of trauma from occlusion at an unfamiliar site: A rare case report." Biomedicine 43, no. 01 (2023): 528–31. http://dx.doi.org/10.51248/.v43i01.1691.

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The radicular cyst is a common visitant in a dental office especially dealing with the non-vital tooth. It is a sequela of apical periodontitis, and it is often associated with carious teeth. Trauma from occlusion, in the long run, will lead to apical periodontitis. The association of radicular cyst with trauma from occlusion is rare, and this case report is one such incidence. A 38- year -old male patient reported with the chief complaint of mobility and swelling in the lower front teeth region for one month. Radiographs revealed a radiolucency around the apices of the mandibular central and
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Postnikov, M. A., A. M. Golovachev, S. E. Chigarina, D. N. Kudryashov, I. A. Zakharova, and S. A. Burakshaev. "Clinical diagnostic approach in the treatment of chronic periodontitis in mandibular molars: Clinical cases." Kuban Scientific Medical Bulletin 30, no. 5 (2023): 100–112. http://dx.doi.org/10.25207/1608-6228-2023-30-5-100-112.

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Background. Inflammatory process in periapical tissues causes tooth extraction in more than 50% of cases. The development of chronic apical periodontitis can be triggered by an intracanal infection in undetected/missed root canal of the mandibular molars. The morphology of mandibular molars is distinguished by additional canals in the mesial root in some cases. Different studies reveal the middle mesial canal in 4.5% to 26% of cases with quite high incidence in youth. The dental therapy has been searching for effective approaches to diagnosis and treatment of chronic periodontitis, enabling th
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Frolova, K. E., L. A. Zyulkina, A. V. Yurkevich, and A. V. Efremova. "Comprehensive assessment of the effectiveness of diagnosis and treatment of patients with chronic apical periodontitis based on microbiological and joulemetric research methods." Medical alphabet, no. 11 (May 12, 2024): 77–80. http://dx.doi.org/10.33667/2078-5631-2024-11-77-80.

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Background. An increase in the number of patients with chronic apical periodontitis is becoming a global trend, which is mediated by several factors: the formation of foci of chronic infection, an increase in the number of various odontogenic complications leading to the loss of a causal tooth, a decrease in general resistance and the development of persistent sensitization of the body.The aim of the study was to evaluate the effectiveness of diagnostic measures based on a complex of microbiological and joulemetric methods in patients with chronic apical periodontitis.Materials and methods. 25
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Герасимова, Лариса, Larisa Gerasimova, Алина Юсупова, et al. "COMPARATIVE EFFECTIVENESS OF TREATMENT OF CHRONIC APICAL PERIODONTITIS ON THE BASIS OF DENSITOMETRIC AND MICROBIOLOGICAL RESEARCH METHODS." Actual problems in dentistry 15, no. 2 (2019): 17–24. http://dx.doi.org/10.18481/2077-7566-2019-15-2-17-24.

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Relevanct of the research topic. One of the possible causes of apical periodontitis is the infectious inflammatory process of the periapical periodontal tissues. The microflora of the root canal system is represented by various microorganisms, among which streptococci, enterococci and staphylococci most often prevail. The complex anatomy of the root canal system ensures the growth and reproduction of microorganisms, and the endodontic treatment does not always contribute to their qualitative and quantitative reduction. 
 Purpose ― study of the effectiveness of endodontic treatment of chro
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33

Kostyrenko, О. P., V. L. Melnyk, V. K. Shevchenko, Yu I. Sylenko, and G. A. Yeroshenko. "APPLICATION OF NANOCRYSTALS IN TREATMENT OF CHRONIC APICAL PERIODONTITIS." World of Medicine and Biology 16, no. 73 (2020): 061. http://dx.doi.org/10.26724/2079-8334-2020-3-73-61-65.

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34

Demyanenko, S. A., Yu V. Tofan, and I. M. Tkachenko. "MODERN ASPECTS IN THE TREATMENT OF CHRONIC APICAL PERIODONTITIS." Bulletin of Problems Biology and Medicine 4 (2018): 254. http://dx.doi.org/10.29254/2077-4214-2018-4-1-146-254-258.

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35

Braz-Silva, Paulo Henrique, Mariana Lobo Bergamini, Andressa Pinto Mardegan, Catharina Simioni De Rosa, Bengt Hasseus, and Peter Jonasson. "Inflammatory profile of chronic apical periodontitis: a literature review." Acta Odontologica Scandinavica 77, no. 3 (2018): 173–80. http://dx.doi.org/10.1080/00016357.2018.1521005.

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Costa, Tatiana Hassin Rodrigues, José Albuquerque de Figueiredo Neto, Ana Emilia Figueiredo de Oliveira, Mariana de Figueiredo Lopes e. Maia, and Aiza Leal de Almeida. "Association between Chronic Apical Periodontitis and Coronary Artery Disease." Journal of Endodontics 40, no. 2 (2014): 164–67. http://dx.doi.org/10.1016/j.joen.2013.10.026.

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37

Rocas, I. N., and J. F. Siqueira. "Root Canal Microbiota of Teeth with Chronic Apical Periodontitis." Journal of Clinical Microbiology 46, no. 11 (2008): 3599–606. http://dx.doi.org/10.1128/jcm.00431-08.

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38

Шалаев, O. Shalaev, Некрылов, D. Nekrylov, Селина, and Olesya Selina. "The analysis of treatment results of chronic apical periodontitis." Journal of New Medical Technologies. eJournal 8, no. 1 (2014): 1–4. http://dx.doi.org/10.12737/4797.

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Forms of chronic periodontitis, treatment results and long-term results are traditionally defined on the basis of X-ray examination. Today, the most modern and reliable method for diagnostic X-ray examination opportunities in dentistry is dental cone-beam computed tomography. In comparison with other methods of X-ray examination in dentistry the method of dental cone-beam computed tomography has a number of advantages: the ability to make measurements of distances, the density of solid tissue, angles and areas in any part of the data at any angle, at any height, length, width up to 0,125 mm du
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39

Shaiymbetova, A. R., D. B. Shayakhmetov, and S. K. Sulaimankulova. "LONG-TERM RESULTS OF TREATMENT OF CHRONIC APICAL PERIODONTITIS." Vestnik of the Kyrgyz-Russian Slavic University 23, no. 5 (2023): 94–97. http://dx.doi.org/10.36979/1694-500x-2023-23-5-94-97.

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40

Han, Iryna V., Volodymyr M. Zubachyk, Khrystyna H. Musij-Sementsiv, Nataliia I. Bodnaruk, Nataliia V. Porokhovska, and Oksana M. Slaba. "REPARATIVE REGENERATION OF PERIAPICAL TISSUES IN CHRONIC GRANULOMATOUS PERIODONTITIS UNDER THE INFLUENCE OF COMPOSITION BASED ON CALCIUM HYDROXYAPATITE." Wiadomości Lekarskie 74, no. 4 (2021): 832–37. http://dx.doi.org/10.36740/wlek202104104.

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The aim: To establish the dynamics of reparation processes in periapical tissues in chronic granulomatous periodontitis under the influence of the developed composition based on calcium hydroxyapatite in comparison with the generally accepted drug MTA. Materials and methods: The main group included 52 individuals, and the comparison group – 19 patients with chronic granulomatous periodontitis. In the first experimental subgroup, patients were obturated of the tooth root apical area with the proposed composition, and in the second experimental subgroup patients were performed obturation of the
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41

Musienko, A. I., and K. I. Nesterova. "Immediate implantation in a patient with chronic generalized parodontitis and apical granuloma." Periodontology 24, no. 2 (2019): 145–49. http://dx.doi.org/10.33925/1683-3759-2019-24-2-145-149.

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Relevance. Rehabilitation of patients with moderate to severe generalized periodontitis is a leading problem in periodontology. It was the determination of the prospects for immediate implantation in patients with chronic periodontitis, combined with the pathology of the tooth root and maxillary sinus.Materials and methods. A group of 94 people with periodontitis and chronic odontogenic rhinosinus was observed who underwent sinus surgical treatment, tooth extraction and one-stage implantation with FRP growth factor according to the author's technology.Results. The method showed high efciency o
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42

Kumari, K. Swapna, Sangita Dixit, Mahendra Gaur, et al. "Taxonomic Assignment-Based Genome Reconstruction from Apical Periodontal Metagenomes to Identify Antibiotic Resistance and Virulence Factors." Life 13, no. 1 (2023): 194. http://dx.doi.org/10.3390/life13010194.

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Primary apical periodontitis occurs due to various insults to the dental pulp including microbial infections, physical and iatrogenic trauma, whereas inadequate elimination of intraradicular infection during root canal treatment may lead to secondary apical periodontitis. We explored the complex intra-radicular microbial communities and their functional potential through genome reconstruction. We applied shotgun metagenomic sequencing, binning and functional profiling to identify the significant contributors to infection at the acute and chronic apical periodontal lesions. Our analysis reveale
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43

Liu, Yi. "Evaluation of the Effectiveness and Safety of One-Time Endodontics in the Treatment of Chronic Apical Periodontitis with Sinus Tract in Pediatric Deciduous Teeth." Journal of Clinical and Nursing Research 8, no. 6 (2024): 111–16. http://dx.doi.org/10.26689/jcnr.v8i6.6771.

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Objective: To observe the effectiveness and safety of one-time endodontics in the treatment of chronic apical periodontitis with sinus tract in pediatric deciduous teeth. Methods: 109 cases of children with chronic apical periodontitis with sinus tract in the deciduous teeth treated in our hospital from January 2022 to December 2023 were selected and grouped by the randomized numerical table method, with 54 cases in the experimental group and 55 cases in the control group. The experimental group was treated with one-time endodontics and the control group was treated with conventional endodonti
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44

Khabadze, Z. S., D. A. Nazarova, Z. M. Suleimanova, Yu A. Generalova, Yu A. Generalova, and A. P. Kotelnikova. "Microbial biocenosis of apical periodontitis in the root canal system (Part 1)." NEW ARMENIAN MEDICAL JOURNAL, no. 1 (2022): 76–80. http://dx.doi.org/10.56936/18290825-2022.16.1-76.

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The purpose of this review article is to assess systematically the available scientific evidence about difference in microbiota of apical periodontitis in root canals during time and its antibiotic susceptibility. The study of publications was produced in the electronic databases such as Google Scholar, PubMed during a systematic review of the literature. Included articles contain information about microorganisms in the root canal system of different forms of apical periodontitis. The publication date criterion was selected from January 2000 to December 2012. Overall 52 articles were reviewed.
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Lin, Ying, Quan Xing, Wei Qin, et al. "Decreased Expression of Semaphorin3A/Neuropilin-1 Signaling Axis in Apical Periodontitis." BioMed Research International 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/8724503.

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Apical periodontitis (AP) is a chronic infection of endodontic origin accompanied with bone destruction around the apical region. Semaphorin3A (Sema3A) and neuropilin-1 (Nrp1) are regarded as a pair of immune regulators in bone metabolism. In this study, we firstly investigated the expression pattern of Sema3A/Nrp1 in apical periodontitis and its correlation with bone destruction. Using rat animal model, we analysed the level of mandibular bone destruction and the expression of Sema3A/Nrp1 on days 0, 7, 14, 21, 28, and 35 after pulp exposure. In addition, clinical samples from apical periodont
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El Ashiry, Eman A., Najat M. Farsi, Sawsan T. Abuzeid, Mohamed M. El Ashiry, and Hammam A. Bahammam. "Dental Pulp Revascularization of Necrotic Permanent Teeth with Immature Apices." Journal of Clinical Pediatric Dentistry 40, no. 5 (2016): 361–66. http://dx.doi.org/10.17796/1053-4628-40.5.361.

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Objectives: The treatment of immature necrotic teeth with apical periodontitis presents challenges in endodontic and pediatric dentistry. Revascularization is a recent treatment for such cases as an alternative to conventional apexification. The purpose is to examine the effect of a pulpal revascularization procedure on immature necrotic teeth with apical periodontitis. Study design: Twenty patients were enrolled for pulp revascularization procedure by root canal disinfection using a triple antibiotic mixture for 1–2 weeks, followed by creating a blood clot, sealing the root canal orifice usin
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Wang, Lina, Hong Zhang, Ming Dong та ін. "Role of the Btk-PLCγ2 Signaling Pathway in the Bone Destruction of Apical Periodontitis". Mediators of Inflammation 2019 (25 липня 2019): 1–10. http://dx.doi.org/10.1155/2019/8767529.

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Chronic apical periodontitis is characterized by alveolar bone absorption in the apical region and is the result of the participation of various inflammatory mediators. Studies have shown that the Bruton tyrosine kinase- (Btk-) phospholipase Cγ2 (PLCγ2) signaling pathway plays an important role in bone absorption, but it is unknown whether it plays a role in apical periodontitis bone destruction. Therefore, this study verified the role of Btk and PLCγ2 in bone resorption of apical periodontitis by in vivo and in vitro experiments. In the in vivo experiment, a mice model of apical periodontitis
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48

Popov, V. A., E. S. Pestova, and S. A. Anisimova. "Endodontic treatment of teeth with a wide apical opening – a clinical case." Endodontics Today 23, no. 2 (2025): 282–88. https://doi.org/10.36377/et-0094.

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INTRODUCTION. The prevalence of apical periodontitis among the adult population exceeds 60%. This disease also occurs in adolescents in permanent teeth, and it is often detected in a state where the growth zone has died, and it is not possible to treat with calcium hydroxide to achieve apexogenesis. Therefore, there is a need to find and apply the most optimal dental materials for the treatment of dental periodontitis in adolescents. AIM. Presentation of our own clinical case of endodontic treatment of a tooth with a wide apical opening. MATERIALS AND METHODS. The article presents the result o
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Bolyachin, Alexei, Zurab Khabadze, Oleg Mordanov, Magomed Gasbanov, and Takhir Teberdiev. "Symptomatic Apical Periodontitis of the Mandibular First Molar with the Accessory Canal in the Furcation Area Mimicking Furcation Perforation." Case Reports in Dentistry 2022 (May 12, 2022): 1–5. http://dx.doi.org/10.1155/2022/6324447.

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Apical periodontitis frequently presents as a chronic disease. To arrive at a true diagnosis, in addition to the clinical examination, it is mandatory to undertake radiographic examinations and evaluate the clinical presentation. Knowledge of the root canal morphology is a prerequisite for effective nonsurgical endodontic treatment. The internal morphological features of the pulp chamber are variable and complex. This case report describes the treatment and outcome of symptomatic apical periodontitis of a mandibular first molar with the accessory (chamber) canal. The applied treatment fully co
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Plyska, O., E. Chehertma, and O. Lehenchuk. "PERIODONT TISSUES STATUS AND FEATURES OF CLINICAL COURSE OF APICAL PERIODONTITIS OF PERMANENT TEETH WITH DISORDERS OF ROOT FORMATION AS A RESULT OF INJURY." Medical Science of Ukraine (MSU) 16, no. 1 (2020): 52–56. http://dx.doi.org/10.32345/2664-4738.1.2020.08.

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Relevance. In childhood, traumatic tooth injuries are often found. Pulp necrosis occurs in 34,2 % of injured teeth, this causes damage to the periapical tissues. The post-traumatic complications (odontogenic cysts, periodontitis) in teeth with incomplete root formation often lead to a halt in root development. Chronic nidus of infection can be the cause of the somatic pathology development. This makes the early clinical and radiological diagnosis of post-traumatic complications important.
 Objective of the work is to study the clinical features of the post-traumatic periodontitis of perma
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