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Relevant bibliographies by topics / Chronic degenerative disease / Dissertations / Theses

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Dissertations / Theses on the topic 'Chronic degenerative disease'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 February 2022

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1

Vloumidi, Eleni I. "Investigations into the development of chronic degenerative valve disease in dogs." Thesis, University of Nottingham, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.576156.

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In dogs chronic degenerative valve disease (CDVD) is the most common cardiac disorder and the most frequent cause of cardiac failure seen in clinical practice. The aetiology of CDVD is unknown however recent investigations have focused on the molecular mechanisms that may be implicated in the development of the disease. This thesis investigates the impact of mechanical stimuli on the canine mitral valve at both the molecular and clinical level. At the molecular level canine valvular interstitial cells (VICs) were successfully extracted from valve tissue and shown to express proteins related to

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2

Martins, Brigite de Lima Novo Dantas. "Lesão degenerativa crónica da valva mitral em canídeos: epidemiologia e diagnóstico ecocardiográfico : estudo retrospectivo de 41 casos." Bachelor's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2008. http://hdl.handle.net/10400.5/948.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>Esta dissertação é resultado do estágio realizado no Instituto Veterinário do Parque e integra uma exposição breve da casuística acompanhada, uma revisão bibliográfica sobre a Lesão Degenerativa Crónica da Valva Mitral (LDCVM) e o diagnóstico ecocardiográfico desta doença e, finalmente, um estudo clínico dentro deste tema. A LDCVM é a doença cardíaca adquirida mais frequente em canídeos adultos, atingindo principalmente animais a partir dos 8 anos de idade e de raças de pequeno a médio porte, sendo raríssima a sua descrição em

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3

Ueda, Mariana Yukari. "Amplitude de distribuição das hemácias (RDW) e Proteína-C Reativa (CRP) em cães com doença valvar degenerativa crônica mitral." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/10/10136/tde-09122015-105601/.

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O RDW é um índice hematológico utilizado para avaliação quantitativa da anisocitose eritrocitária, sendo útil na diferenciação das causas de quadros anêmicos. Atualmente, na medicina humana, o RDW tem sido considerado como um importante fator prognóstico em quadros de ICC, mesmo na ausência de anemia. A CRP é considerada a principal proteína de fase aguda sendo amplamente utilizada como marcadora de inflamação. O objetivo deste estudo foi determinar se há diferença nos valores do RDW e da concentração da CRP em cães com DVDCM com e sem ICC, bem como nos diferentes estágios (A, B1, B2, C e D) d

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4

Botte, José Martins de Carvalho Sacadura. "Correlações entre achados ecocardiográficos e parâmetros de qualidade de vida em cães com doença degenerativa crónica da válvula mitral." Master's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2012. http://hdl.handle.net/10400.5/4837.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>Contexto: A doença degenerativa crónica da válvula mitral (DDCVM) é a doença cardíaca adquirida mais frequente em canídeos adultos e, pelo seu carácter de progressão crónica, tem um impacto negativo marcado na qualidade de vida dos doentes. A ecocardiografia transtorácica é considerada o método de diagnóstico de eleição para esta doença, e algumas variáveis ecocardiográficas ajudam a identificar animais em risco acrescido de morte. Objectivos: Analisar a existência e significância de correlações entre achados ecocardiográficos

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5

Figueiredo, Andreia Raquel Marques de. "A dilatação atrial esquerda em canídeos : lesão degenerativa crónica da valva mitral como sua principal causa : estudo integrado do biomarcador NT-proBNP." Master's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2012. http://hdl.handle.net/10400.5/4843.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>A dilatação atrial esquerda (DAE) é uma alteração morfológica cardíaca que acompanha grande parte das insuficiências cardíacas, podendo ser consequência de sobrecarga de volume ou de pressão. São variadíssimas as doenças capazes de conduzir a DAE, destacando-se a lesão degenerativa crónica da valva mitral (LDCVM). Esta é a doença cardíaca adquirida mais comum nos canídeos adultos e afeta principalmente raças de pequeno e médio porte. A ecocardiografia é considerada o meio complementar de diagnóstico primordial de DAE, uma vez que é m

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6

Viar, Kenneth E. II. "Role of SARM1 in Chronic Immune-Mediated Central Nervous System Inflammation." VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/5819.

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SARM1 is an injury-induced nicotinamide adenine dinucleotide nucleosidase (NADase) that was previously shown to promote axonal degeneration in response to traumatic, toxic, and excitotoxic stressors. This raises the question of whether a SARM1-dependent program of axonal degeneration is central to a common pathway contributing to disease burden in neurological disorders. The degree to and mechanism by which SARM1 inactivation decreases the pathophysiology of such disorders is of interest to establish the rationale to pursue SARM1 as a therapeutic target. In this study, we compare the course an

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7

Schwartz, Joseph D. "The Prevalence of Comorbid Chronic Disease in Virginia's Adult Patient Population during the Years 2001 and 2004." VCU Scholars Compass, 2005. http://hdl.handle.net/10156/1553.

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8

García, Romero Bernardo Celso. "Estudio cualitativo del perfil del cuidador primario, sus estilos de afrontamiento y el vínculo afectivo con el enfermo oncológico infantil." Doctoral thesis, Universitat Ramon Llull, 2011. http://hdl.handle.net/10803/32141.

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La família és una peça clau en el suport del malalt durant el procés de la malaltia. No obstant això, les conseqüències psicològiques que comporta l'impacte de la malaltia i continus cures, sovint repercuteixen en la seva pròpia salut i per tant en la seva qualitat de vida. Objectiu: El present estudi analitza les principals necessitats del cuidador primari, així com les motivacions per a l'adquisició del rol i el manteniment de la cura. S'han identificat les principals estratègies d'afrontament que empren els cuidadors al llarg del procés de la malaltia per fer front a l'impacte de l'estrè

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9

Berling, Holm Katarina. "The Chorda Tympani Nerve : Role in Taste Impairment in Middle Ear Disease and after Ear Surgery." Doctoral thesis, Uppsala universitet, Centrum för klinisk forskning, Västerås, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-316591.

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The chorda tympani nerve, also known as the taste nerve, runs uncovered through the middle ear cavity, a localization that exposes the nerve to pathological processes and surgical trauma in the middle ear. People operated on for otosclerosis tend to complain more about postoperative taste disturbances than those operated on for chronic otitis media. It has been suggested that this difference may be explained by gradual deterioration of chorda tympani nerve function caused by chronic otitis media infection and that further impairment caused by surgery is less noticeable in these patients. This

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10

Ramalho, Reinaldo Flávio da Costa. "Qualidade de vida visual em pacientes com degeneração macular relacionada à idade neovascular tratados com antiangiogênicos." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5149/tde-24102018-135624/.

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INTRODUÇÃO: A degeneração macular relacionada à idade (DMRI) é a principal causa de perda de visão irreversível e cegueira mundialmente. A perda da visão central interfere nas atividades de vida diária, como o reconhecimento facial, leitura e escrita, direção de veículos automotores e em atividades funcionais e de lazer. Esta perda de visão relaciona-se também com o desencadeamento de quadros de ansiedade e depressão. Este estudo avaliou a qualidade de vida visual em pacientes com degeneração macular relacionada à idade neovascular por meio do questionário de função visual 25-item National Eye

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11

Wang, Shih-Kai, and 王師凱. "Prospective study of disease progression of chronic degenerative mitral disease in dogs." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/48911943631416268193.

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碩士<br>國立中興大學<br>獸醫學系暨研究所<br>101<br>Mitral regurgitation (MR) attributable to chronic mitral valve insufficiency (CMVI), is the most common heart disease in dogs. Previously reported risk factors in dogs for progression of disease include age, gender, intensity of heart murmur, degree of valve prolapse, severity of valve lesions, and the degree of mitral valve regurgitation. However, these studies have generally been conducted on specific breeds such as Dachshund or Cavalier King Charles; the progression of disease and prognostic data of the breed which common in Taiwan are thus not available.

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12

Wu, Shih-Yang, and 伍世揚. "Clinical Efficacy of Benazepril in Dogs with Chronic Degenerative Valvular Diseases." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/74098275991302507777.

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碩士<br>國立臺灣大學<br>獸醫學研究所<br>97<br>Abstract Benazepril, an angiotensin converting enzyme inhibitor, potently suppresses renin-angiotensin-aldosterone system, and is widely used in humans and dogs with hypertension, cardiac diseases, and renal diseases. In clinical studies, benazepril has been proven to have beneficial effect on hemodynamic parameters, clinical conditions, exercise endurance and survival times in dogs with congestive heart failure. Moreover, effect of benazepril on slowing down the progression of renal disease in patients with chronic renal insufficiency has been demonstrated

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13

Wang, Shih-Wan, and 汪士琬. "The Serum Concentration of Cardiac Troponin I in Association of Dogs with Chronic Degenerative Valvular Diseases." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/98825995578199509099.

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碩士<br>國立臺灣大學<br>獸醫學研究所<br>97<br>Biomarkers have been extensively used in human and veterinary medicine, and divided into two groups: the leakage markers and functional makers. Cardiac troponin I (cTnI), a structure protein of cardiomyocyte, is a sensitive, specific, is a leakage marker for cardiac injury. N-terminal-pro B-type natriuretic peptide (NT-proBNP), a hormone exerts a variety of effects of maintaining circulatory homeostasis in states of increased extracellular volume, is a functional maker. The thesis includes two sections: first part, association NT-proBNP and cTnI of clinically he

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14

Klinck, Mary P. "Development and psychometric validation of pain scales in feline osteoarthritis." Thèse, 2017. http://hdl.handle.net/1866/19883.

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15

Cheng, Qi. "Age-related Macular Degeneration and Vascular and Renal Comorbidities in Adults Aged 40 Years or Older: NHANES 2005-2008." 2014. http://scholarworks.gsu.edu/iph_theses/344.

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ABSTRACT IMPORTANCE: Age-related macular degeneration (AMD) is a leading cause of low vision in elderly population. The association of vascular and renal conditions has been reported inconsistently. Unfolding the association may provide the insight to eye care providers to take account general health management into eye care. OBJECTIVES: To investigate the prevalence of the vascular and renal comorbidities with AMD, examine the association of a single or combination of these comorbidities with AMD. DSIGN AND PARTICIPANTS: Population-base cross-sectional study involved the adults aged 40 years

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16

Bouchard, Micheline. "L'expérience de femmes atteintes de sclérodermie et vivant avec une limitation fonctionnelle : une étude phénoménologique." Thèse, 2013. http://hdl.handle.net/1866/10996.

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17

Lee, Li Fen, and 李麗芬. "Exploring the Impact of Silymarin on the Risk of Age-related macular degeneration in Patients with Chronic Hepatic Diseases." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/h55s46.

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18

Lin, Chi-Chun, and 林繼群. "Use of inhaled corticosteroids or theophylline and risk of cataract, glaucoma and age-related macular degeneration among chronic obstructive pulmonary disease patients: A population-based retrospective nested case-control study in Taiwan." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/40943217950289952265.

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碩士<br>國立中央大學<br>資訊工程學系<br>102<br>Chronic obstructive pulmonary disease is an irreversible lung disease. The leading cause of death ranked seventh in Taiwan. According to COPD guideline when patient enter into the third stage. They recommend using inhaled corticosteroids to heal, theophylline is also recommended that patients taking one of the medicines. Theophylline occupies the highest proportion of drug use in Taiwan. The effect of theophylline on eyes doesn’t have clearly results yet. Cataracts, glaucoma, age-related macular degeneration are all common eye diseases on elder. Cataract affect

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19

Mesquita, Miguel Ângelo Martins. "Purification and characterization of dysfunctional lysosomes in an age-related macular disease cell model." Master's thesis, 2021. http://hdl.handle.net/10362/113763.

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RESUMO:O declínio da função lisossomal tem sido apontado como estando envolvido numa série de doenças crónicas relacionadas com a idade, nomeadamente em doenças neurodegenerativas, cancro, aterosclerose e retinopatias. Neste projeto colocamos a hipótese de que lisossomas disfuncionais adquirem propriedades únicas e marcadores específicos, distinguindo-se dos funcionais. Durante este trabalho, usámos o epitélio pigmentar da retina humana como modelo celular para identificar as propriedades intrínsecas de lisossomas disfuncionais. O epitélio pigmentar da retina é responsável pela fagocitos

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