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Dissertations / Theses on the topic 'Chronic disease'

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1

Williams, Stacey L., and E. Fekete. "Chronic Disease." Digital Commons @ East Tennessee State University, 2012. https://dc.etsu.edu/etsu-works/8145.

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Jaishankar, Gayatri. "Chronic Granulomatous Disease." Digital Commons @ East Tennessee State University, 2009. https://dc.etsu.edu/etsu-works/8869.

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3

Ye, Ping. "Autoimmunity in chronic periodontitis." Thesis, The University of Sydney, 2003. http://hdl.handle.net/2123/4256.

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Profound perturbation of epithelial structure is a characteristic feature of the immunopatholoical response to bacterial antigens considered to be central in the pathogenesis of the destructive lesion of periodontitis. The pathological basis for the disturbance of epithelial structure is not understood. It was demonstrated that the structural integrity and functional differentiation of the lining epithelium is compromised in relation to inflammatory changes associated with destructive periodontitis. In the pathological lining epithelium of the periodontal pocket there was a marked reduction of
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4

Ye, Ping. "Autoimmunity in chronic periodontitis." University of Sydney, 2003. http://hdl.handle.net/2123/4256.

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Doctor of Philosophy<br>Profound perturbation of epithelial structure is a characteristic feature of the immunopatholoical response to bacterial antigens considered to be central in the pathogenesis of the destructive lesion of periodontitis. The pathological basis for the disturbance of epithelial structure is not understood. It was demonstrated that the structural integrity and functional differentiation of the lining epithelium is compromised in relation to inflammatory changes associated with destructive periodontitis. In the pathological lining epithelium of the periodontal pocket there w
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5

Philips, L. G. "Disease management in chronic kidney disease /." abstract and full text PDF (free order & download UNR users only), 2005. http://0-wwwlib.umi.com.innopac.library.unr.edu/dissertations/fullcit/1430446.

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Thesis (M.B.A.)--University of Nevada, Reno, 2005.<br>"May, 2005." Includes bibliographical references (leaves 92-97). Online version available on the World Wide Web. Library also has microfilm. Ann Arbor, Mich. : ProQuest Information and Learning Company, [2005]. 1 microfilm reel ; 35 mm.
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6

Ye, Ping. "Autoimmunity In Chronic Periodontitis." Thesis, The University of Sydney, 2003. http://hdl.handle.net/2123/4872.

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7

Ormarsdóttir, Sif. "Osteoporosis in chronic liver disease." Doctoral thesis, Uppsala University, Department of Medical Sciences, 2001. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-660.

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<p>Ormarsdóttir, S. 2001. Osteoporosis in Chronic Liver Disease. Acta Universitatis Upsaliensis. <i>Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine</i> 1037. 60 pp. Uppsala. ISBN 91-554-5021-0. </p><p>Osteoporosis is a well-known and frequently reported complication of chronic liver disease (CLD) with a high fracture rate contributing to significant morbidity after liver transplantation. The pathogenesis is unknown and controversy exists about many risk factors for osteoporosis in CLD. </p><p>In the present thesis, bone mineral density (BMD) was found to be signif
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Ormarsdóttir, Sif. "Osteoporosis in chronic liver disease /." Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-5021-0/.

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9

Begbuna, Veronica. "Haemodynamics in chronic venous disease." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.401816.

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10

Leslie, Wilma S. "Weight management and chronic disease." Thesis, University of Glasgow, 2009. http://theses.gla.ac.uk/1300/.

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Abstract Background: Obesity, in addition to being a serious condition in its own right, is causally associated with many chronic non-communicable diseases, and its prevention, identification and treatment is a public health priority. Results: The main findings of the present thesis were that 1) many drugs, used in the management of chronic disease, have an adverse effect on body weight with weight change of +10kg observed as a real side effect of some. 2) Identification and management of obesity is not a formal part of current practice in many secondary care clinics. While acknowledging the a
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11

Wong, Germaine. "Cancer and chronic kidney disease." Thesis, The University of Sydney, 2008. https://hdl.handle.net/2123/28229.

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Introduction Chronic kidney disease (CKD) is a common and important public health problem, with significant impact on the person’s quality of life and chances of survival. Cardiovascular disease is major cause of morbidity and mortality among people with CKD. Cancer is also a well-recognised complication in people on dialysis and with kidney transplants, but has not been adequately assessed in people with mild to moderately reduced kidney function. It is uncertain whether the basis of such increased risk in the end-stage kidney and transplant populations is solely related to their immunocompr
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12

Laba, Tracey-Lea. "Medication Adherence in Chronic Disease." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/9546.

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Background: Chronic disease places a substantial health and economic burden on individuals and health systems globally. Effective chronic disease management relies on patient adherence to proven medications. Medication adherence rates in chronic disease are sub-optimal, yet adherence-enhancing intervention results are underwhelming. Potentially, current strategies are not matching patient adherence preferences, nor addressing heterogeneity in adherence behaviour between social groups. To inform effective intervention design, this thesis aimed to explore adherence preferences for chronic diseas
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13

Joshi, S., and David L. Wood. "Telementoring for Chronic Disease Management." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/5165.

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14

Biati, Raquel Marie. "Chronic Disease Self-Management Program." ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2598.

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The World Health Organization noted that 2 global health problems have reached epidemic proportions: obesity and type 2 diabetes. These conditions affect nearly 170 million people worldwide. The clinical practice problem addressed by this project was the prevalence of adults ages 50 and older in an ambulatory care setting who suffer from obesity and diabetes and may benefit from a tailored weight management and nutrition education intervention. The purpose of this project was to design a program that would decrease body mass index and hemoglobin A1c in older patients through adaption of the Ch
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15

McAllister, David Anthony. "Chronic obstructive pulmonary disease, pulmonary function and cardiovascular disease." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5615.

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Cardiovascular disease is common in Chronic Obstructive Pulmonary Disease (COPD), and forced expiratory volume in one second (FEV1) independently predicts cardiovascular morbidity and mortality. Pathological changes in the systemic vasculature have been proposed as potential mechanisms linking COPD to cardiovascular disease, and patients with COPD may be at increased risk of acute myocardial infarction during acute exacerbations. Notwithstanding causation, FEV1 may be a useful prognostic marker in patients undergoing cardiac surgery. This thesis examined these three aspects of cardiovascular c
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16

Murphy, Nicola. "Chronic obstructive pulmonary disease and anxiety." Thesis, Coventry University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368862.

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17

Danesh, John. "Chronic infection and coronary heart disease." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326020.

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18

Tomlinson, Laurie. "Arterial Stiffness and Chronic Kidney Disease." Thesis, University of Brighton, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518323.

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Introduction: Chronic kidney disease (CKD) common, particularly in the elderly, and is linked to an increased risk of cardiovascular disease (CVD). This is partly explained by joint risk factors such as hypertension and diabetes but novel risk factors such as arterial stiffness, arterial calcification and endothelial dysfunction may play a role. Our aims were 1) to prospectively investigate whether aortic stiffness was linked with rate of decline of renal dysfunction, 2) to investigate the associations of arterial stiffness in patients with moderate renal dysfunction, and 3) to investigate whe
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19

Aravinthan, Aloysious Dominic. "Hepatocyte senescence in chronic liver disease." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708050.

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20

Thomas, James A. "Cell therapy for chronic liver disease." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/19553.

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There is a growing literature of clinical studies of bone marrow (BM) cell therapy for liver cirrhosis. At present, the optimum choice of cell type(s) and the mechanism(s) of effect remain undefined. Cells of the monocyte-macrophage lineage have key roles in the development and resolution of liver fibrosis. Therefore, I tested the therapeutic effects of these cells in the context of experimental murine liver fibrosis. The effects of unmanipulated, syngeneic macrophages, their specific BM precursors and unfractionated (whole) BM cells were examined in the iterative carbon tetrachloride model of
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21

Navaneethan, Sankar. "METABOLIC SYNDROME AND CHRONIC KIDNEY DISEASE." Case Western Reserve University School of Graduate Studies / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=case1401967446.

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22

Xie, Jeffrey Xinshuo. "Molecular Insights into Chronic Kidney Disease." University of Toledo Health Science Campus / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=mco1500201100900825.

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23

White, Joanna D. "Investigations into feline chronic kidney disease." Thesis, The University of Sydney, 2010. https://hdl.handle.net/2123/28931.

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Chronic kidney disease (CKD) is arguably the most common disease of older cats. A disproportionate number of younger, male cats with CKD was identified among a cohort of cats with CKD and was hypothesised to be due to membranous glomerulopathy or an FIV associated nephropathy. Examination of epidemiologic, histologic, immunohistologic and survival data revealed an association between the presence of CKD and FIV infection among young cats and an adverse effect of FIV infection on survival among cats with CKD, but no specific histological changes were seen among FIV positive cats. Glomer
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24

Vidot, Marie Helen. "Nutrition Interventions and Chronic Liver Disease." Thesis, The University of Sydney, 2019. https://hdl.handle.net/2123/21592.

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Background The liver has an integral role in all metabolic processes Hypothesis Identification of nutritional abnormalities in patients with CLD facilitates targeted nutrition intervention to improve patient outcomes Aim To investigate specific nutritional features and interventions in patients with CLD Methods The population was adults with CLD All investigations were approved by the Sydney Local Health District Research Ethics and Governance Office Studies included: Retrospective analysis of subjective global assessment (SGA), obesity, malnutrition and muscle wasting in patients with CLD
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25

Lindholm, Michelle Marie. "Chronic childhood disease and child abuse." CSUSB ScholarWorks, 1998. https://scholarworks.lib.csusb.edu/etd-project/1559.

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The purpose of the present research is to investigate whether or not chronically ill children are victims of child abuse more frequently than healthy children. The gender of the child and of the parent will also be examined for differences in the treatment children receive.
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26

Kirsch, Florian [Verfasser]. "Economic aspects of disease management programs in chronic diseases / Florian Kirsch." München : Verlag Dr. Hut, 2018. http://d-nb.info/1164293648/34.

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27

Ramzan, Naveen, Shimin Zheng, Hemang Panchal, Edward Leinaar, Christian Nwabueze, and Timir K. Paul. "Investigating The Association Between Chronic Kidney Disease and Clinical Outcomes." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/21.

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Background Chronic Kidney Disease (CKD) can be described as the loss of the kidney function over time. Symptoms usually develop slowly, and it may not appear in early stages. Lab tests can confirm a CKD diagnosis. The approximate number of incidents per year is more than 200,000 cases, and approximately 30 million people are living with CKD today in the United States. This long-standing disease ultimately leads to renal failure at the end. At this present time, there are no known cures for CKD, and the only treatment available is dialysis. Objectives The purpose of this study is to determine
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28

Graves, Carolyn Mary. "Comparing parents' and nurses' identification and prioritization of parental needs in the context of caring for children with chronic conditions." Thesis, University of British Columbia, 1991. http://hdl.handle.net/2429/29728.

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Accurate assessment is the foundation on which effective nursing interventions rest. However, it is not known how accurately nurses identify and prioritize the needs of parents whose children have chronic conditions. When nurses proceed with interventions based on inaccurate assessments, the results can be unsuccessful interventions that neither meet parental needs nor provide optimal health care for this population of children. This descriptive comparative study was conducted to 1) examine parental needs identified and prioritized by parents of children with chronic conditions and their resp
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29

Soicher, Judith Eileen. "A longitudinal study of physical activity behaviour in chronic disease: the example of chronic obstructive pulmonary disease." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=32532.

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In chronically ill adults, involvement in physical activity is associated with reduced mortality and better quality of life. In chronic obstructive pulmonary disease (COPD), exercise training within a pulmonary rehabilitation program leads to improvements in dyspnea, exercise capacity and quality of life measured immediately after the program. These gains diminish within 6-18 months of program completion, in part due to patients' difficulty in sustaining physical activity behaviour. The global objective o
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30

So, Beng Hock. "Chronic kidney disease : determining chronicity, prevalence, variation and survival in a community chronic kidney disease (CKD) cohort." Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/30671/.

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Chronic kidney disease (CKD) is insidious and most cases are diagnosed through opportunistic serum creatinine (SCr) testing before symptoms develop. However, efforts to accurately assess prevalence have been hampered by the lack of a universally agreed definition of SCr thresholds for the diagnosis of CKD. At the turn of the millennium, two crucial developments occurred. The first was the description of the Modification of Diet in Renal Disease estimated Glomerular Filtration Rate (eGFR) which closely correlated to cumbersome measured GFR and could be used instead in daily clinical practice. T
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31

Harbord, Marcus William Nixon. "Investigation of acute inflammation in Crohn's disease and chronic granulomatous disease." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399572.

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32

Roos-Engstrand, Ester. "T cells in chronic obstructive pulmonary disease." Doctoral thesis, Umeå : Umeå university, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-33677.

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33

Stevenson, Nicola Jane. "Lung mechanics in chronic obstructive pulmonary disease." Thesis, University of Liverpool, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432977.

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34

Hermans, Marcus Matheus Hendrik. "Arterial wall abnormalities in chronic kidney disease." Maastricht : Maastricht : Universitaire Pers Maastricht ; University Library, Universiteit Maastricht [host], 2007. http://arno.unimaas.nl/show.cgi?fid=9384.

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35

Urb, Mirjam. "Mechanisms of «Aspergillus fumigatus» chronic airway disease." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110500.

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Colonization of airways by Aspergillus fumigatus hyphae in immunocompetent patients with chronic lung disease leads to progressive decline in pulmonary function. While a minority of these patients develop a severe allergic response to the fungus, the majority of patients show a decline in lung function and airway hyperreactivity despite the absence of elevated IgE levels, eosinophilia or other evidence of hypersensitivity. Treatment of these non-allergic patients with antifungal drugs improves the symptoms, suggesting that pulmonary complications might be directly caused by A. fumigatus. Th
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36

Hood, Vivienne Claire. "Neurogenic influences on chronic inflammatory joint disease." Thesis, Queen Mary, University of London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.252151.

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37

Wodehouse, Theresa. "Ciliary aspects of chronic sino-pulmonary disease." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271952.

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38

Parham, Rhian. "Caregiver burden in paediatric chronic kidney disease." Thesis, Canterbury Christ Church University, 2011. http://create.canterbury.ac.uk/10347/.

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Section A provides an overview of the role of family caregivers of individuals with chronic illness, and describes key conceptualisations and theories posited in the caregiver literature. This is followed by an overview of research conducted with caregivers of children with chronic kidney disease (CKD), a summary of the limitations of this research, and suggestions for future research. Section B Despite a recognised need to monitor caregiver burden in caregivers of children with CKD, there is no measurement tool currently available to meet this aim. The present research documents the developme
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Cash, W. J. "Disordered Vascular Compliance in Chronic Liver Disease." Thesis, Queen's University Belfast, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.517250.

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40

Al-shair, Khaled. "Systemic Manifestations of Chronic Obstructive Pulmonary Disease." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509061.

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41

Parkes, Dr Julie. "Non-invasive biomarkers in chronic liver disease." Thesis, University of Southampton, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509473.

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42

Revill, Susan M. "Endurance exercise in chronic obstructive pulmonary disease." Thesis, Loughborough University, 1997. https://dspace.lboro.ac.uk/2134/15388.

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43

White, David James. "Haemophilus in acute and chronic respiratory disease." Thesis, Liverpool John Moores University, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304425.

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44

Poustie, Vanessa Jane. "Dietary interventions for children with chronic disease." Thesis, University of Liverpool, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269705.

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45

Polkey, Michael Iain. "Diaphragm function in chronic obstructive pulmonary disease." Thesis, King's College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286262.

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46

Woolf, Adrian Spencer. "Atrial natriuretic factor and chronic renal disease." Thesis, Imperial College London, 1990. http://hdl.handle.net/10044/1/46615.

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47

Roberts, Helen Michelle. "Neutrophil function in chronic inflammatory disease states." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/7018/.

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Inflammation is a central component of the immune response. In its acute form it aids the transition from disease to health via the activation of numerous immune cells, enabling them to reach the site of infection/injury and orchestrate themselves to combat pathogens, facilitating resolution and repair to restore the host to health. However, chronic inflammation is deleterious to the host and differs from the “classical” acute inflammatory process in that the inflammation is not necessarily so readily obvious and is not self-limiting; rather, the immune system is in a constant state of low-gra
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48

Eckerblad, Jeanette. "Symptom burden among people with chronic disease." Doctoral thesis, Linköpings universitet, Hälsa, Aktivitet, Vård (HAV), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-122742.

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Introduction: Chronic diseases tend to increase with old age. Older people with chronic disease are commonly suffering from conditions which produce a multiplicity of symptoms and a decreased health-related quality of life. Nurses have a responsibility to prevent, ease or delay a negative outcome through symptom management, or assist in achieving an acceptable level of symptom relief. Aim: The overall aim of the thesis was to describe different aspects of symptom burden from the perspective of community-dwelling people with chronic disease. Methods: This thesis is based upon four papers that u
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49

Donaldson, Anna. "Circulating microRNA in Chronic Obstructive Pulmonary Disease." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/24776.

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Skeletal muscle dysfunction in COPD is associated with increased morbidity. Novel agents might reverse skeletal muscle dysfunction through different mechanisms since the biopsy picture in COPD patients is heterogenous. Thus there is a need for a biomarker of skeletal muscle dysfunction which could both be measured in blood and obviate the need for a biopsy. Previous work has found that muscle-specific microRNA (miR-1, miR-499, miR-206 and miR-133) are down-regulated in the quadriceps of COPD patients. Tissue specific miRNA circulate in the blood at detectable levels and are currently under inv
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50

Dias, Daniel de Matos. "Platform for chronic respiratory disease patient management." Master's thesis, Universidade de Aveiro, 2013. http://hdl.handle.net/10773/11560.

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Mestrado em Engenharia de Computadores e Telemática<br>As doenças respiratórias são uma das razões mais frequentes para consultas médicas e uma das causas de morte mais frequentes a nível mundial, representando gastos de vários milhões de euros. A frequência e grau de severidade de ocorrência de tosse é um dos principais indicadores a analisar, por ser este o sintoma mais frequente em grande parte destas doenças respiratórias e por ser também um bom indicador da evolução do estado do paciente. Dada a importância deste sintoma, foi desenvolvido o Leicester Cough Monitor, uma aplicação que perm
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