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Relevant bibliographies by topics / Chronic HBV

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Academic literature on the topic 'Chronic HBV'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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Journal articles on the topic "Chronic HBV"

1

Ola, Samuel O., Jesse A. Otegbayo, Georgina N. Odaibo, et al. "Occult HBV infection among a cohort of Nigerian adults." Journal of Infection in Developing Countries 3, no. 06 (2009): 442–46. http://dx.doi.org/10.3855/jidc.415.

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Objective: To determine markers of HBV infection and detect the presence of its occult infection in serum of a cohort of adult Nigerians. Methodology: The study involved 28 adult Nigerians with viral hepatitis (Group 1) and 28 apparently healthy adult Nigerians as controls (Group 2). Their sera were assayed for HBsAg, HBeAg, anti-HBe, anti-HBc, anti-HBs, and anti-HCV, while HBV DNA was determined in 15 patients with chronic hepatitis. Significance of differences between the patients and control subjects was assessed using Chi-square test at a 95% confidence level. Results: Sero-detection of HB

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Komitova, Radka T., Ani K. Kevorkyan, Maria V. Atanasova, Aneta V. Ivanova, and Elica Golkocheva-Markova. "Booster immunity – diagnosis of chronic hepatitis B viral infection." Journal of Infection in Developing Countries 13, no. 03 (2019): 255–60. http://dx.doi.org/10.3855/jidc.9929.

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Introduction: Diagnosis of chronic hepatitis B virus (HBV) infection particularly its occult form requires monitoring and repeat serological and molecular studies. The aim of the study was to investigate the possible relation between the case of a family outbreak of hepatitis A and the finding that a member of this family was diagnosed with chronic hepatitis B. Methodology: A mother and her two sons, one previously diagnosed with chronic HBV infection, were hospitalized due to suspected acute hepatitis. Serological markers for hepatitis A, hepatitis B and hepatitis C were assessed. Addit

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Batayneh, Naji, and Salwa Bdour. "Risk of Perinatal Transmission of Hepatitis B Virus in Jordan." Infectious Diseases in Obstetrics and Gynecology 10, no. 3 (2002): 127–32. http://dx.doi.org/10.1155/s1064744902000121.

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Objectives:To determine the risk of perinatal transmission of hepatitis B virus (HBV) in Jordan.Methods: Plasma samples from 1000 pregnant Jordanian women were screened by ELISA for HBV markers (HBsAg, HBeAg, anti-HBe, anti-HBc and anti-HBs).Results:HBsAg and HBeAg were detected in 4.3% and 0.1% of the pregnant women, respectively. The overall prevalence of antibodies was 6%, 11.1% and 7.5% for anti-HBe, anti-HBc and anti-HBs, respectively. Women were assignedto four groups according to the serological patternsofHBV markers: susceptible (85.9%), with acute infection (2.9%), with chronic infect

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Tao, Mi-Hua, Ya-Hui Huang, Ho-Yuan Chou, and Cheng-Chieh Fang. "A mouse model of T cell dysfunction in chronic Hepatitis B (105.24)." Journal of Immunology 186, no. 1_Supplement (2011): 105.24. http://dx.doi.org/10.4049/jimmunol.186.supp.105.24.

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Abstract The virus-host interactions responsible for dysfunctions of hepatitis B virus (HBV)-specific T cells and the subsequent development of severe liver diseases are poorly understood. Mice are not naturally infected by HBV, presumably due to a lack of HBV receptors on mouse hepatocytes. To bypass this entry step of HBV infection, we used adeno-associated viral vectors to introduce the HBV genome (AAV/HBV) into the liver of immunocompetent mice. We confirmed the presence of HBV virions and proteins in the serum and liver of all AAV/HBV-transduced mice. These mice were negative for HBV surf

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Mohamed Mustafa Abbas, Shahd, Walla Saeed Eltahir Saeed, Osama Mohamed Musa, et al. "Immune-pathological phases of chronic Hepatitis B infections among Sudanese individuals towards personalization of management." Journal of Human Virology & Retrovirology 8, no. 1 (2020): 1–5. http://dx.doi.org/10.15406/jhvrv.2020.08.00212.

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Background: Hepatitis B virus (HBV) infection is an immune liver disease affecting millions worldwide. Despite availability of an efficacious vaccine, elimination of HBV infections is aloft. This study aimed to identify the immune-pathological phases of chronic HBV infection (CHBV) among Sudanese individuals to refine management strategies. Materials and methods: In a prospective cross-sectional study and following informed consent, 1593 individuals with HBs Ag reactivity were enrolled. Serum total protein/ albumin, ALT, AST, total bilirubin, HBs Ag/Ab, HBe Ag/Ab, HBc IgM/HBc total antibodies

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Abdulkhudhur Al-Zubaidi, Mohsin, Masoumeh Bahreini, Mohammad Reza Sharif moghadam, and Wissam Saleh Abood Al-Rubaye. "Detection and determination of hepatitis B using molecular and serological methods in patients with hepatitis B in Al-Diwaniya Iraq." AL-QADISIYAH MEDICAL JOURNAL 15, no. 1 (2019): 87–97. http://dx.doi.org/10.28922/qmj.2019.15.1.87-97.

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Hepatitis B virus (HBV) is one of the most prevalent pathogens in the world and infection with this virus is a serious threat for public health. The pathogenesis of HBV depends on the critical interplay between viral and host factors.  Test 88 samples for the detection of serological markers using ELISA and PCR technique for positive HBsAg. Regarding population group (HBsAg) positive, the seroprevalence rate of HBsAg, anti-HBs, anti-HBc IgM, HBc Total HBeAg , anti-HBe and HBV DNA were 25%, 5%, 12%, 10%, 9%, 17% and 22% respectively. In this study, hepatitis was diagnosed with the followi

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Buxton, Jane A., and Jin Hee Kim. "Hepatitis A and Hepatitis B Vaccination Responses in Persons with Chronic Hepatitis C Infections: A Review of the Evidence and Current Recommendations." Canadian Journal of Infectious Diseases and Medical Microbiology 19, no. 2 (2008): 197–202. http://dx.doi.org/10.1155/2008/410362.

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In persons with chronic hepatitis C virus (HCV) infections, superinfection by hepatitis A virus (HAV) or hepatitis B virus (HBV) can cause serious complications, including fulminating hepatitis or increased severity of hepatitis. Therefore, it is important to adequately protect persons with chronic HCV infections by immunization. Suboptimal response to vaccines has been reported in patients with chronic liver disease. The present article reviews HAV and HBV vaccine responses reported in the literature when administered to individuals with chronic HCV infection, and reviews current national and

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Paschereit, Anissa, Vivien Greese, Kayo Sakurayama, et al. "Impact of Hepatitis B Infection on Patient and Graft Survival After Kidney Transplantation." Journal of Clinical Medicine 14, no. 6 (2025): 2124. https://doi.org/10.3390/jcm14062124.

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Objectives: Chronic Hepatitis B virus (HBV) infection is a significant global health issue, with dialysis patients at increased risk and reduced response to HBV vaccination. The effects of HBV serological status on kidney transplant outcomes, particularly for patients with resolved or inactive HBV infection, needs more data, especially from current era. This study evaluated the impact of chronic and non-active HBV infection on patient and graft survival after kidney transplantation. Methods: Retrospective analysis was conducted of kidney-only transplant recipients at our center from 1 January

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Frelin, Lars, Therese Wahlström, Amy E. Tucker, et al. "A Mechanism To Explain the Selection of the Hepatitis e Antigen-Negative Mutant during Chronic Hepatitis B Virus Infection." Journal of Virology 83, no. 3 (2008): 1379–92. http://dx.doi.org/10.1128/jvi.01902-08.

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ABSTRACT Hepatitis B virus (HBV) expresses two structural forms of the nucleoprotein, the intracellular nucleocapsid (hepatitis core antigen [HBcAg]) and the secreted nonparticulate form (hepatitis e antigen [HBeAg]). The aim of this study was to evaluate the ability of HBcAg- and HBeAg-specific genetic immunogens to induce HBc/HBeAg-specific CD4+/CD8+ T-cell immune responses and the potential to induce liver injury in HBV-transgenic (Tg) mice. Both the HBcAg- and HBeAg-specific plasmids primed comparable immune responses. Both CD4+ and CD8+ T cells were important for priming/effector function

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Fang, Lily, Amanda Yu, and Jane A. Buxton. "Identification of Acute Vaccine-Preventable Hepatitis in Individuals with Chronic Hepatitis in British Columbia between 1991 and 2007." Canadian Journal of Infectious Diseases and Medical Microbiology 22, no. 1 (2011): 10–14. http://dx.doi.org/10.1155/2011/564290.

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BACKGROUND: In British Columbia (BC), hepatitis A virus (HAV) and hepatitis B virus (HBV) vaccines are provincially funded for persons with chronic hepatitis infections. PURPOSE: To assess the effectiveness of BC public health follow-up of HBV and hepatitis C virus (HCV) cases and immunization policy by determining the number of vaccine-preventable acute hepatitis infections reported following a chronic HBV or HCV diagnosis, by examining demographic characteristics and by observing temporal trends.METHODS: All newly identified cases of HAV, HBV and HCV between 1991 and October 2007 were extrac

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Dissertations / Theses on the topic "Chronic HBV"

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Hultgren, Catharina. "Immune modulation in chronic HBV and HCV infection /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4255-2/.

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Dumpis, Uga. "Epidemiological and molecular studies on chronic HBV infection in Gambian families." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340721.

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Das, A. "Constraints on the CD8 T cell response in chronic HBV infection." Thesis, University College London (University of London), 2009. http://discovery.ucl.ac.uk/14916/.

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The inflamed liver in chronic hepatitis B virus infection (CHB) is characterised by a large influx of non-virus specific CD8 T cells, which we hypothesize could provide insights into mechanisms of failure of viral control and liver damage in this setting. We compared the effector function of total circulating and intrahepatic CD8 T cells in CHB patients and healthy donors. We demonstrated that CD8 T cells from CHB patients, regardless of their antigen specificity, were impaired in their ability to produce IL-2 and proliferate upon TCR dependent stimulation. By contrast, these CD8 T cells had p

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Ogbu, Stella Chinyere. "Role of Topoisomerase II alpha in DNA Topology and T cell responses during Chronic Viral Infections." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etd/3661.

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The clearance of viruses is largely dependent upon the activation of T cells to generate a robust immune response. However, host responses are suppressed during chronic viral infections. In this thesis, we explored the role of Top2α in DNA topology in individuals with chronic HBV, HCV, and HIV infections. We found that Top2α protein expression and activity were low in T cells derived from chronically virus-infected individuals compared to healthy subjects. Using CD4+ T cells treated with Top2α inhibitor or poisoner as a model, we demonstrated that Top2α inhibition disrupts the DNA topology, su

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Lee, Wing-yan. "Association of cytokine gene polymorphisms with susceptibility and disease progression in chronic hepatitis B virus (HBV) infection." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/HKUTO/record/B39556955.

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Lee, Wing-yan, and 李穎欣. "Association of cytokine gene polymorphisms with susceptibility and disease progression in chronic hepatitis B virus (HBV) infection." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39556955.

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Sum, Siu-man Simon, and 岑紹文. "The development and assessment of assays for quantitation of hepatitisB virus DNA (HBV DNA) and the clinical significance of low HBV DNAlevel in patients with chronic hepatitis B." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B3013836X.

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Tout, Issam. "Rôle du TLR9 et des lymphocytes B dans l'échappement du virus de l'hépatite B à l'immunité innée." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1308/document.

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L'infection chronique par le virus de l’hépatite B (HBV) est un problème de santé majeur dans le monde et peut conduire à la cirrhose et à l’hépatocarcinome. Des réponses défectives des cellules T ont été démontrées, mais les événements précis qui peuvent contribuer à l'insuffisance des réponses des cellules B restent à déterminer. L'expansion et la différenciation optimales des cellules B reposent sur l'activité du récepteur Toll Like Receptor 9 (TLR9) qui détecte l'ADNdb et est exprimée chez l'homme principalement par les cellules dendritiques plasmacytoïdes (pDC) et les cellules B. L'impact

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Zhou, Jie. "Genetic polymorphisms of type I interferon receptor 1 affect the susceptibility to chronic HBV infection association analysis and mechanistic investigation /." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38722951.

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周婕 and Jie Zhou. "Genetic polymorphisms of type I interferon receptor 1 affect the susceptibility to chronic HBV infection: association analysis and mechanistic investigation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B38722951.

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Books on the topic "Chronic HBV"

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Lindh, Gudrun. Chronic hepatitis B: Impact of hepatitis D virus superinfection and the hepatitis B e-system on histological outcome, and correlation of the hepatitis B e-system to HBV-DNA in serum. Distributed by the Almqvist & Wiksell Periodical Co., 1986.

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institutet, Karolinska, ed. Chronic hepatitis B: Impact of hepatitis D virus superinfection and the hepatitis B e-system on histological outcome, and correlation of the hepatitis B e-system to HBV-DNA in serum. Distributed by Almqvist & Wiksell Periodical Co., 1986.

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Merlin, Jessica S., Peter A. Selwyn, Glenn J. Treisman, and Angela G. Giovanniello, eds. Chronic Pain and HIV. John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781118777374.

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Berkhout, Ben, Hildegund C. J. Ertl, and Marc S. Weinberg, eds. Gene Therapy for HIV and Chronic Infections. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2432-5.

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McDonald, John R. HIV, AIDS and hemophilia: Perspectives on chronic illness. UT Back-in-Print Service, 1999.

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McDonald, John R. HIV, AIDS and hemophilia: Perspectives on chronic illness. The AIDS and Hemophelia Support and Education Program of the Calgary Region, 1989.

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McDonald, John R. HIV, AIDS and hemophilia: Perspectives on chronic illness. Canadian Hemophilia Society, 1989.

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Marvin, Stein, and Baum Andrew, eds. Chronic diseases. L. Erlbaum Associates, 1995.

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Lou, Galantino Mary, ed. Clinical assessment and treatment of HIV: Rehabilitation of a chronic illness. Slack, 1992.

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ANRS-VESPA, Groupe. SIDA, une maladie chronique passée au crible: Enquête nationale sur le quotidien des personnes infectées. Presses de l'école des hautes études en santé publique, 2008.

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Book chapters on the topic "Chronic HBV"

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Angtuaco, Terence L., and Donald M. Jensen. "HBV and HCV Co-Infection." In Chronic Viral Hepatitis. Humana Press, 2002. https://doi.org/10.1007/978-1-59259-104-6_6.

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Esteban, James. "Immune-Tolerant Chronic HBV." In Managing Complex Cases in Gastroenterology. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-48949-5_90.

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Esteban, James. "Immune-Active Chronic HBV." In Managing Complex Cases in Gastroenterology. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-48949-5_91.

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Köse, Şükran, and Tuba Dal. "Laboratory Diagnosis of HBV." In Viral Hepatitis: Chronic Hepatitis B. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-93449-5_5.

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Inan, Nese, and Fehmi Tabak. "Current Management of Chronic HBV Infection." In Viral Hepatitis: Chronic Hepatitis B. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-93449-5_7.

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Esteban, James. "Differentiating Acute HBV from an Acute Exacerbation of Chronic HBV." In Managing Complex Cases in Gastroenterology. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-48949-5_93.

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Rukunuzzaman, Md, Md Benzamin, and Kaniz Sultana. "Management of Chronic HBV Infection in Children." In Viral Hepatitis: Chronic Hepatitis B. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-93449-5_2.

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Demirel, Aslıhan, and Resat Ozaras. "Future Drugs in the Treatment of HBV." In Viral Hepatitis: Chronic Hepatitis B. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-93449-5_9.

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Karaca, Nilay, and Çetin Karaca. "Prevention of Mother-to-Child Transmission of HBV." In Viral Hepatitis: Chronic Hepatitis B. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-93449-5_6.

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Stasi, Cristina, Laura Gragnani, and Anna Linda Zignego. "Fibrosis Assessment in Patients with HCV or HBV Chronic Infection." In Liver Elastography. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-40542-7_9.

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Conference papers on the topic "Chronic HBV"

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Hardwick, R. Alan, Bruce L. Levine, Carl H. June, et al. "Development of Closed Systems for Ex Vivo Cell Processing: Utility in Cell and Gene Therapy." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-1316.

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Abstract Two examples are described in which cells were processed in a closed sterile fluid path by using custom-designed instruments, plastic bags and tubing sets, and a sterile connection device. In the first example, nucleated blood cells were collected from HIV+ patients. These cells were enriched for CD4+ cells and the CD4+ cells were expanded in the presence of immobilized CD3 and CD28 antibodies. The cells were then concentrated, washed, and re-infused. For the largest batches this resulted in 2.20 × 1010 cells with 86% viability and a CD4+ cell purity ≥ 95%. In two out of three re-infu

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Castro, Ana Rita Motta, Livia Lima, Larissa Bandeira, et al. "Hepatitis B: changes in epidemiological features of Afrodescendant communities in Central Brazil." In XIII Congresso da Sociedade Brasileira de DST - IX Congresso Brasileiro de AIDS - IV Congresso Latino Americano de IST/HIV/AIDS. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/dst-2177-8264-202133p142.

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Introduction: Hepatitis B virus (HBV) infection is still a concern in vulnerable populations. In a study performed by our team in 1999–2003 in two Afro-Brazilian communities, Furnas dos Dionísios (FD) and São Benedito (SB), high prevalence rates of HBV exposure (42.7% and 16.0%, respectively), high susceptibility to HBV (55.3% and 63.0%, respectively) and low HBV vaccination like profile rates (2.0% and 21.0%, respectively) were observed. Objective: In 2015–2016, we reassessed epidemiological and molecular features of HBV in these two communities to verify the impact of health actions adopted

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Berezovscaia, Elena. "Evaluarea stării de sănătate a pacienților cu hepatopatii cronice cu ajutorul indicatorilor fiziologici." In "Fiziologia şi sănătatea", congresul fiziologilor. Bulletin of the Academy of Sciences of Moldova. Medical Sciences, 2025. https://doi.org/10.52692/cfzl2024.11.

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Chronic hepatopathies present one of the important medical issues in Moldova having leading place in terms of incidence and severity. The aim: to study physiological indices in patients with chronic hepatopathies. There were examined 59 patients: 34 - with chronic HBV infection (HBV gr.), 25 - with associated metabolic steatosis liver disease (MASLD gr.), 26 apparently healthy people entered the control group (CG). The indices of systolic (APs) and diastolic (APd) arterial pressure, pulse rate (RPs) and Kerdo Vegetative Index (KVI) were evaluated. The APs average values in the MASLD gr. were 1

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Kocić, Biljana, Marina Kostić, and Vesna Stošić. "Epidemiological characteristics of hepatitis B in the Nišava district." In Proceedings of the International Congress Public Health - Achievements and Challenges. Institute of Public Health of Serbia "Dr Milan Jovanović Batut", 2024. http://dx.doi.org/10.5937/batutphco24037k.

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Background: Although there are effective vaccines and treatment strategies against hepatitis B, it is still a significant health concern in Serbia and worldwide. Methods and Objectives: The objective was to assess epidemiological characteristics, incidence and trend of hepatitis B in the Nišava District in the period 2011-2020. Descriptive epidemiological method was applied. Data for the study were provided by Annual Reports of Communicable Diseases of the Institute of Public Health Niš. Incidence rates (IR) were calculated per 100,000 inhabitants. Results: A total of 496 HBV cases were regist

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Heim, Kathrin, Sagar Sagar, Maike Hofmann, and Robert Thimme. "Enforced cytotoxic signature of HBV pol455-specific CD8 T cells in chronic HBV infection." In 38. Jahrestagung der Deutsche Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag, 2022. http://dx.doi.org/10.1055/s-0041-1740660.

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Heim, K., B. Bengsch, D. Wieland, et al. "TOX expression on HBV specific CD8+ T cells is linked to clinical stage of chronic HBV infection." In 36. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0039-3402203.

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Urbanek-Quaing, Melanie, Katja Steppich, Manoj Kumar Gupta, et al. "Enhancing HBV-Specific T Cell Responses through Epigenetic Modulation and Immune Checkpoint Inhibition in Chronic HBV Infection." In 40. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag, 2024. http://dx.doi.org/10.1055/s-0043-1777635.

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Singh, Angad, Sophie McKenna, Cumlat Lourdes, and Deepak Suri. "PTU-136 Improving care for patients with chronic hepatitis B(HBV)." In British Society of Gastroenterology, Annual General Meeting, 4–7 June 2018, Abstracts. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2018. http://dx.doi.org/10.1136/gutjnl-2018-bsgabstracts.514.

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Rakić, Violeta, and Jelena Simić. "Analysis of trends in the incidence of acute hepatitis B virus infection in the Republic of Serbia in the period from 2003 to 2022." In Proceedings of the International Congress Public Health - Achievements and Challenges. Institute of Public Health of Serbia "Dr Milan Jovanović Batut", 2024. http://dx.doi.org/10.5937/batutphco24128r.

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Background: Hepatitis B virus (HBV) is a common worldwide blood-borne pathogen. WHO estimates that 254 million people were living with chronic hepatitis B infection in 2022, with 1.2 million new infections each year. In 2022, hepatitis B resulted in an estimated 1.1 million deaths, mostly from cirrhosis and hepatocellular carcinoma (primary liver cancer). Hepatitis B can be prevented by vaccines that are safe, available and effective. Chronic hepatitis B can progress to an inactive carrier state, and then, in some patients, give rise to cirrhosis and cancer of the liver, leading to death. An H

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Seidl, S. "SCREENING PROCEDURES TO PREVENT TRANSMISSION OF HEPATITIS B, NON-A,NON-B, AND AIDS BY BLOOD TRANSFUSION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644753.

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Although the number of infectious agents capable of being transmitted through blood and blood products is vast, only a few cause problems in recipients of a magnitude which warrants the need for screening tests. The most important agents are Hepatitis B Virus (HBV), Hepatitis non-A,non-B (HNANB) - agents causing posttransfusion hepatitis (PTH) and the human immundeficiency viruses (HIV) responsible for transfusion associated AIDS (TAA).PTH: Prospective studies in open-heart-surgery patients demonstrated a high prevalence (8-17%) *in Spain, Italy, the United States and Israel whereas low percen

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Reports on the topic "Chronic HBV"

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Tangkijvanith, Pisit. Prevalence and Clinical Significance of Hepatitis B Viral Genotypes and Mutations. Faculty of Medicine, Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.24.

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Hepatitis B virus (HBV) infection is a major public health problem, with more than 400 million HBV carriers estimated worldwide. Chronic HBV infection is associated with a diverse clinical spectrum of liver damage ranging from asymptomatic carrier status, chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC). There have been increasing lines of evidence to indicate influences of HBV genotypes and mutations on the outcome of liver disease, particularly the development of HCC. The project is aimed to study the prevalence and clinical significance of genotypes and mutations in Precore/

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Hajarizadeh, Behzad, Jennifer MacLachlan, Benjamin Cowie, and Gregory J. Dore. Population-level interventions to improve the health outcomes of people living with hepatitis B: an Evidence Check brokered by the Sax Institute for the NSW Ministry of Health, 2022. The Sax Institute, 2022. http://dx.doi.org/10.57022/pxwj3682.

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Background An estimated 292 million people are living with chronic hepatitis B virus (HBV) infection globally, including 223,000 people in Australia. HBV diagnosis and linkage of people living with HBV to clinical care is suboptimal in Australia, with 27% of people living with HBV undiagnosed and 77% not receiving regular HBV clinical care. This systematic review aimed to characterize population-level interventions implemented to enhance all components of HBV care cascade and analyse the effectiveness of interventions. Review questions Question 1: What population-level interventions, programs

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Chen, Mao-bing, Hua Wang, Qi-han Zheng, Wei-yan Cui, Hua-lan Xu, and Xu-wen Zheng. Comparative efficacy of the front-line anti-HBV drugs in nucleos(t)ide analogue-naive chronic hepatitis B, A protocol for systematic review and network meta-analysis. INPLASY - International Platform of Registered Systematic Review Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.3.0016.

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Ciapponi, Agustín. Do decision support and clinical information systems improve the healthcare process and health outcomes for people living with HIV? SUPPORT, 2016. http://dx.doi.org/10.30846/161013.

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The overall number of people living with HIV has steadily increased, as HIV treatments extend life. As HIV infection is shifting mostly to a chronic disease managed primarily in the ambulatory setting, chronic disease management interventions such as decision support and clinical information systems might be useful to this population.

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Library, Spring. How Close are We Really to the HIV Cure? Spring Library, 2020. http://dx.doi.org/10.47496/sl.blog.20.

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The virus’ tricky, constantly mutating nature has so far made it impossible to develop an effective vaccine, even as the constantly improving antiviral drug classes have made HIV infection a manageable chronic health condition.

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Zheng, Ruo-xiang, Xun Li, Jing Li, et al. Does Chinese herbal remedy Tangcao tablet work for the treatment of HIV/AIDS：a systematic review of controlled clinical trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.6.0042.

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Review question / Objective: This study aims to evaluate the effectiveness and safety of Tangcao tablet (Tangcao) for treating people with HIV/AIDS. Condition being studied: Acquired immunodeficiency syndrome (AIDS) is a chronic infectious disease characterized by severe immunodeficiency caused by the human immunodeficiency virus (HIV). The infection attacks specifically the white blood cells, CD4+T (CD4) cells, weakening the immunity of individuals against infections such as tuberculosis. Without treatment, patients with AIDS may survive up to 2 years. Pneumocystis pneumonia and infections of

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Savedoff, William D., Laura Goyeneche, Luis Alberto Soler, et al. Disruption and Rebound: Healthcare and Telemedicine in Colombia during the COVID-19 Pandemic for Chronic Care Patients. Inter-American Development Bank, 2023. http://dx.doi.org/10.18235/0004865.

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The COVID-19 pandemic led to declines in in-person consultations and substantial increases in telemedicine use in many countries. This paper investigates whether this pattern occurred in Colombia using data for people with particular health conditions prior to the pandemic (rheumatoid arthritis, hemophilia, chronic kidney disease, HIV, and cancer). The study shows that healthcare utilization by people in Colombia with these conditions dropped significantly during the first months of the pandemic relative to the average of the previous two years. However, by the end of 2020, the rate of healthc

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Kamma, Dr Prudhvi Srujan, and Dr Aishwarya Badugu. AN UNUSUAL PRESENTATION OF EXTRAPULMONARY TUBERCULOSIS AS FEVER WITH PANCYTOPENIA: A CASE REPORT. World Wide Journals, 2023. http://dx.doi.org/10.36106/ijar/5105754.

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Background: In the developing countries, tuberculosis is a signicant health issue. The vague presentation causes extrapulmonary tuberculosis to take longer to be diagnosed. Pancytopenia is one of the haematological symptoms of extrapulmonary tuberculosis. Pancytopenia may result from hypersplenism, maturation arrest, hemophagocytic lymphohistiocytosis, or inltration of the bone marrow by caseating or noncaseating granulomas causing reversible or irreversible brosis. We Case presentation: report a case of a 70 year-old man who presented with pyrexia of unknown origin with signicant loss of

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Reproductive tract infections: A set of factsheets. Population Council, 1999. http://dx.doi.org/10.31899/rh1999.1015.

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Reproductive tract infections (RTIs) are being increasingly recognized as a serious global health problem with impact on individual women and men, and their families and communities. RTIs can have severe consequences, including infertility, ectopic pregnancy, chronic pelvic pain, miscarriage, and increased risk of HIV transmission. For effective prevention and management of RTIs, accurate information is necessary and should be widely available. In addition to a brief introduction to RTIs, this document contains 13 factsheets addressing medical and social issues on a variety of topics related t

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