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Journal articles on the topic 'Chronic immobilization stress'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

JUNJUA, BASHIR AHMAD. "ACUTE AND CHRONIC IMMOBILIZATION STRESS;." Professional Medical Journal 20, no. 01 (2012): 150–55. http://dx.doi.org/10.29309/tpmj/2013.20.01.580.

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ABSTRACT…Objective: To compare the morphological changes induced by acute and chronic immobilization in vermal cerebellarcortex of young male sprague dawley rats with special reference to Purkinje cells. Study design: It was experimental. Setting:Department of Anatomy CPSP Reional Centre, Islamabad. Period: 2005 to 2007. Material and method: A total of 120 young maleSprague Dawley rats were taken and divided equally in two groups (n=60 in each). Both these groups were divided further into twosubgroups (n=30 in each) control acute (CA), immobilized acute (IA), control chronic (CC) and immobiliz

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2

JUNJUA, BASHIR AHMAD. "ACUTE AND CHRONIC IMMOBILIZATION STRESS;." Professional Medical Journal 19, no. 06 (2012): 848–53. http://dx.doi.org/10.29309/tpmj/2012.19.06.2466.

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Objective: The purpose of this article is to compare the morphological changes induced by acute immobilization with thoseproduced by chronic immobilization, in vermal cerebellar cortex of young male sprague dawley rats. Study design: Experimental study.Setting: Department of Anatomy CPSP Regional Centre, Islamabad. Period: 2005 to 2007. Material and method: A total of 120 young maleSprague Dawley rats were taken and divided equally in two groups for acute and chronic immobilization stress. Both these groups were dividedfurther into two subgroups (n=30 in each) control acute, experimental acute

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3

Roger, Sebastien Ndjock, Clarisse Okomolo Moto Fleur, Pierre Omam Omam Jean, Stephanie Kameni Njapdounké Jacqueline, Mbom Alain, and Ngo Bum Elisabeth. "Effects of Phragmanthera capitata (Loranthaceae) on a model of anxiety-like behaviours induced by chronic immobilization stress in mice." GSC Advanced Research and Reviews 17, no. 2 (2023): 129–43. https://doi.org/10.5281/zenodo.10614964.

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This work aims to evaluate the anxiolytic-like effects of <em>Phragmanthera capitata</em> in a model of chronic immobilization stress in mice. Groups of mice were treated in ten consecutive days as follows: a normal control group (NaCl 0.9% per os), a negative control group (chronic immobilization stress + NaCl 0.9% per os), three test groups that were submitted to chronic immobilization stress (CIS) and received three doses of the plant (25, 125, and 250 mg/kg, p.o), and a positive control group (chronic immobilization stress + diazepam 2 mg/kg, i.p). Open field and dark/light tests

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Bitgul, Gulsah, Isil Tekmen, Didem Keles, and Gulgun Oktay. "Protective Effects of Resveratrol against Chronic Immobilization Stress on Testis." ISRN Urology 2013 (November 6, 2013): 1–10. http://dx.doi.org/10.1155/2013/278720.

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Objective. The aim of this study was to investigate protective effects of resveratrol, a strong antioxidant, against possible negative effects of chronic immobilization stress on testes of male rats histochemically, immunohistochemically, ultrastructurally, and biochemically. Material and Methods. Male Wistar rats were divided into 4 groups (n=7). Group I, control group (C), was not exposed to stress. Group II, stress group (S), was exposed to chronic immobilization stress. In Group III, low dose resveratrol + stress group (LRS), rats were given 10 mg/kg/day resveratrol just before the stress

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5

Himcheva, Ivelina, Galya Tz. Stavreva, Emilia Naydenova, and Adriana Bocheva. "Involvement of the opioidergic and nociceptinergic systems in the analgesic effects of novel nociceptin analogues after acute and chronic immobilization stress." Pharmacia 69, no. (4) (2022): 935–42. https://doi.org/10.3897/pharmacia.69.e89379.

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Stress is known to exert an influence on neuroendocrine, autonomic, hormonal functioning. Various stress models have been reported to induce analgesia. This is a phenomenon, referred to as stress-induced analgesia (SIA). Nociceptin/Orphanin FQ(N/OFQ) is a heptadecapeptide that has been found to play a direct role on pain perception. This study aimed to investigate the effects of novel nociceptin analogues on nociception after acute and chronic immobilization stress (CIS) and the involvement of the opioid and nociceptinergic systems in analgesic effects. Analgesic effects were examined by paw-p

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6

Patidar, Govind, and ANIS Shaikh. "Antistress Potential of Glycyrrhizin in Chronic Immobilization Stress." Biomedical & Pharmacology Journal 5, no. 2 (2012): 273–83. http://dx.doi.org/10.13005/bpj/355.

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7

Oksana, Mishchenko, Zaychenko Ganna, Sharifov Churshed, Koshova Оlena, Larianovskaya Julia, and Khalieieva Olena. "Influence of extract of peach ordinary (persica vulgaris) leaves on the state of thymic-lymphatic element of the immune system of rats in conditions of chronic immobilization stress." ScienceRise: Pharmaceutical Science, no. 3(13) (June 29, 2018): 13–18. https://doi.org/10.15587/2519-4852.2018.135748.

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<strong>The aim</strong> – study of the influence of thick extract of peach ordinary (Persica vulgaris) leaves (TEPL) on the state of thymic-lymphatic element of the immune system of rats in conditions of chronic immobilization stress. <strong>Materials and methods.</strong> The model of chronic immobilization stress was reproduced for 18 days by daily four hour immobilization of rats in tight box. Investigated TEPL, which was obtained at the Department of Chemistry of Natural Compounds of National University of Pharmacy from peach leaves of the Salve variety harvested in Tajik

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Valeeva, E. V., I. Kh Valeeva, I. I. Semina, et al. "Dopamine receptors genes activity under chronic stress in rats." Biomics 13, no. 1 (2021): 1–7. http://dx.doi.org/10.31301/2221-6197.bmcs.2021-1.

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Stress response is a multifactorial condition which is formed under extreme environmental exposure due to various neuroendocrine systems interactions. Dopaminergic system plays a key role in stress response through the dopamine which effect is realized after binding with special dopamine receptors types D1-D5. Expression of these receptors varies in different tissues, organs and specific brain structures but there is a special interest in their genes expression level in peripheral blood that can be served as additional marker to evaluate the chronic stress degree. Herein we determine the influ

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9

Himcheva, Ivelina, Galya Tz Stavreva, Emilia Naydenova, and Adriana Bocheva. "Involvement of the opioidergic and nociceptinergic systems in the analgesic effects of novel nociceptin analogues after acute and chronic immobilization stress." Pharmacia 69, no. 4 (2022): 935–42. http://dx.doi.org/10.3897/pharmacia.69.e89379.

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Abstract:

Stress is known to exert an influence on neuroendocrine, autonomic, hormonal functioning. Various stress models have been reported to induce analgesia. This is a phenomenon, referred to as stress-induced analgesia (SIA). Nociceptin/Orphanin FQ(N/OFQ) is a heptadecapeptide that has been found to play a direct role on pain perception. This study aimed to investigate the effects of novel nociceptin analogues on nociception after acute and chronic immobilization stress (CIS) and the involvement of the opioid and nociceptinergic systems in analgesic effects. Analgesic effects were examined by paw-p

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10

Yamanaka, K., I. Muramatsu, and S. Kigoshi. "Effect of chronic nicotine treatment against repeated immobilization stress." Pharmacology Biochemistry and Behavior 26, no. 2 (1987): 259–63. http://dx.doi.org/10.1016/0091-3057(87)90115-8.

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11

Roger Sebastien Ndjock, Fleur Clarisse Okomolo Moto, Jean Pierre Omam Omam, Jacqueline Stephanie Kameni Njapdounké, Alain Mbom, and Elisabeth Ngo Bum. "Effects of Phragmanthera capitata (Loranthaceae) on a model of anxiety-like behaviours induced by chronic immobilization stress in mice." GSC Advanced Research and Reviews 17, no. 2 (2023): 129–43. http://dx.doi.org/10.30574/gscarr.2023.17.2.0420.

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This work aims to evaluate the anxiolytic-like effects of Phragmanthera capitata in a model of chronic immobilization stress in mice. Groups of mice were treated in ten consecutive days as follows: a normal control group (NaCl 0.9% per os), a negative control group (chronic immobilization stress + NaCl 0.9% per os), three test groups that were submitted to chronic immobilization stress (CIS) and received three doses of the plant (25, 125, and 250 mg/kg, p.o), and a positive control group (chronic immobilization stress + diazepam 2 mg/kg, i.p). Open field and dark/light tests were used for the

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12

Viter, U. V., P. G. Lykhatskyi, L. D. Tupol, and O. I. Hrymalyuk. "Morphological changes of the exocrine part of the pancreas under immobilization stress on the background of hypothyrosis." Reports of Vinnytsia National Medical University 26, no. 3 (2022): 376–79. http://dx.doi.org/10.31393/reports-vnmedical-2022-26(3)-05.

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Annotation. Stress is a condition that causes the body's cells to use large amounts of energy to acclimate to abnormal environmental conditions. Hypothyroidism affects almost all organs and systems of the body, in particular, the pancreas. The goal of our research is to study the effect of chronic immobilization stress against the background of hypothyroidism on the tissue structure of the exocrine part of the pancreas. The experimental rats were divided into three groups: I – intact animals (10), II – animals with immobilization stress (10), III – animals with hypothyroidism and immobilizatio

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13

Volchegorsky, I. A., V. Е. Tseilikman, O. L. Kolesnikov, et al. "Hypoglycemic effect of stress exposures and their use for experimental prevention of diabetes mellitus." Problems of Endocrinology 41, no. 6 (1995): 38–42. http://dx.doi.org/10.14341/probl11494.

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The effects of acute and chronic immobilization stress and of a biogenic stressor, prooxidant (neutrophilokin) on the level of glycemia and resistance to diabetogenic exposures were studied in rats. A relationship between the poststress changes in glycemia and the regime of food intake has been revealed: acute stress on an empty stomach led to hypoglycemia, whereas stress without alimentary deprivation caused hyperglycemia. Prestress of fed animals abolished the hypoglycemic effect of stress on an empty stomach and transformed it into a hyperglycemic reaction which could be prevented by obsida

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14

Aguilera, G., D. S. Jessop, M. S. Harbuz, A. Kiss, and S. L. Lightman. "Differential regulation of hypothalamic pituitary corticotropin releasing hormone receptors during development of adjuvant-induced arthritis in the rat." Journal of Endocrinology 153, no. 2 (1997): 185–91. http://dx.doi.org/10.1677/joe.0.1530185.

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Abstract The expression of corticotropin releasing hormone (CRH) in the hypothalamic paraventricular nucleus (PVN) and CRH receptor mRNA in the PVN and anterior pituitary was studied during development of adjuvant-induced arthritis in Piebald–Viral–Glaxo rats, using in situ hybridization techniques. As previously shown with i.p. hypertonic saline injection, basal and immobilization stress-stimulated CRH mRNA levels in the PVN were significantly lower than in controls 14 days after adjuvant injection. However, 7 days after injection, preceding the onset of inflammation, the increase of CRH mRNA

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15

Farkhondeh, Tahereh, Saeed Samarghandian, Fariborz Samini, and Ali Rajabpour Sanati. "Protective Effects of Crocetin on Depression-like Behavior Induced by Immobilization in Rat." CNS & Neurological Disorders - Drug Targets 17, no. 5 (2018): 361–69. http://dx.doi.org/10.2174/1871527317666180515120212.

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Background & Objective: Crocetin, an active ingredient of saffron, has been recognized as a potent antioxidant. Plant extracts or their components may be useful in ameliorating the various diseases, including neurodegenerative disorders. This study investigated the effects of crocetin on oxidative damage induced by chronic restraint stress in the rat brain. For this reason, rats were kept in the restrainers for 1 hour every day, for 21 consecutive days. The animals were injected crocetin (20, 40, 60 mg/kg) or vehicle daily for 21 days. Findings showed that the immobility time significantly

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16

Elias, PC, LL Elias, M. Castro, J. Antunes-Rodrigues, and AC Moreira. "Hypothalamic-pituitary-adrenal axis up-regulation in rats submitted to pituitary stalk compression." Journal of Endocrinology 180, no. 2 (2004): 297–302. http://dx.doi.org/10.1677/joe.0.1800297.

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The present study investigated the hypothalamic-pituitary-adrenal (HPA) axis activity in response to stress in adult male rats submitted to pituitary stalk compression (PSC) or sham operation. Animals received water or oral salt loading (2% NaCl) for one or eight days before the day of the experiment. On the 14th day post-surgery rats were killed under basal conditions or after 15 min immobilization stress. In the PSC group urine output increased significantly and plasma vasopressin (AVP) levels failed to respond to osmotic stimuli. Short-term salt load induced a significant increase in AVP le

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17

Sobhy, Noha S., Mona A. Ahmed, Noha N. Lasheen, Walaa Baher, and Mohamed H. ElSayed. "Olive oil Ameliorates renal Ischemia-reperfusion-mediated hepatic and renal changes in stressed rats." Traditional Medicine and Modern Medicine 07 (January 2024): 13–33. http://dx.doi.org/10.1142/s2575900024500010.

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Background: Renal ischemia-reperfusion injury (IRI) does not only affect kidneys, but also affects remote organs especially the liver. Stress may lead to further progression of renal and hepatic insults. This study was planned to explore the efficacy of olive oil (OO) on the assumed renal and hepatic changes of immobilization stress following renal IRI. Methods: Seventy-seven adult male Wistar albino rats were divided into the following five groups; Sham-Operated Control group, Renal Ischemia-Reperfusion group, Stressed Renal Ischemia-Reperfusion group, OO-Supplemented Renal Ischemia-Reperfusi

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18

Bahaa El-Dein, Ienass, Mona Ahmed, Nevine Soliman, Noha Lasheen, Doaa Abou-Bakr, and Fatma Mohamed. "Sex Differences in Metabolic Responses to Chronic Immobilization Stress in Rats." Bulletin of Egyptian Society for Physiological Sciences 40, no. 1 (2020): 148–65. http://dx.doi.org/10.21608/besps.2019.18674.1036.

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19

Toziuk, O. Yu, O. V. Kryvoviaz, T. I. Ivko, and A. S. Voronkina. "PHARMACOLOGICAL EFFECTS OF KB-28 COMPOUND UNDER CHRONIC IMMOBILIZATION STRESS CONDITIONS." World of Medicine and Biology 14, no. 63 (2018): 160. http://dx.doi.org/10.26724/2079-8334-2018-1-63-160-163.

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20

Nishio, Matomo, Shigeru Kigoshi, and Ikunobu Muramatsu. "Effects of chronic nicotine treatment on the immobilization stress in rats." Japanese Journal of Pharmacology 55 (1991): 280. http://dx.doi.org/10.1016/s0021-5198(19)39228-5.

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21

Bensi, N., M. Bertuzzi, A. Armario, and H. F. Gauna. "Chronic Immobilization Stress Reduces Sodium Intake and Renal Excretion in Rats." Physiology & Behavior 62, no. 6 (1997): 1391–96. http://dx.doi.org/10.1016/s0031-9384(97)00197-2.

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22

Sh.X., Xomidchonova, Karimov V.A., Abdulxakimov A.R., and Ganizhonov P.X. "Morphofunctional Analysis of The State of The Rectum Under Stress (Literature Review)." European International Journal of Multidisciplinary Research and Management Studies 5, no. 2 (2025): 39–47. https://doi.org/10.55640/eijmrms-05-02-11.

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Stress-induced changes in the rectum involve structural and functional alterations affecting its integrity and physiological role. This study examines histological modifications in the rectal wall under immobilization stress, emphasizing epithelial integrity, vascular reactions, and connective tissue remodeling. Morphometric analysis reveals mucosal atrophy, increased inflammatory infiltration, and microcirculatory disturbances. Functional assessments indicate impaired motility and altered mucus secretion, potentially predisposing to chronic pathologies. These findings highlight the significan

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23

Pavlova, Olena, and Viktor Sirenko. "INFLUENCE OF CHRONIC IMMOBILIZATION STRESS ON THE PARAMETERS OF NONSPECIFIC HUMORAL IMMUNITY IN RATS." Sworld-Us Conference proceedings, usc16-01 (January 30, 2019): 32–34. http://dx.doi.org/10.30888/2709-2267.2023-16-01-023.

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The role of the imbalance of regulatory cytokines in the blood of rats under conditions of chronic immobilization stress, compared with the control, in the implementation of immune mechanisms of pancreatic damage was considered, where it was established:

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24

Ammersdörfer, Sandra, Sarah Galinski, and Karl-Heinz Esser. "Effects of aversive experience on the behavior within a custom-made plus maze in the short-tailed fruit bat, Carollia perspicillata." Journal of Comparative Physiology A 198, no. 10 (2012): 733–39. https://doi.org/10.5281/zenodo.13474535.

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(Uploaded by Plazi for the Bat Literature Project) Stress exposure evokes a variety of physiological and behavioral responses in an organism, enabling it to cope with stressful situations and changes in the environment. In a previous study, we found that subjecting individuals of Carollia perspicillata to a chronic immobilization stress paradigm resulted in a significant increase of fecal cortisol concentrations. In the present study, we investigated the influence of stress on the behavior of C. perspicillata, by adapting a commonly used behavioral paradigm for characterizing coping styles of

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25

Ammersdörfer, Sandra, Sarah Galinski, and Karl-Heinz Esser. "Effects of aversive experience on the behavior within a custom-made plus maze in the short-tailed fruit bat, Carollia perspicillata." Journal of Comparative Physiology A 198, no. 10 (2012): 733–39. https://doi.org/10.5281/zenodo.13474535.

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(Uploaded by Plazi for the Bat Literature Project) Stress exposure evokes a variety of physiological and behavioral responses in an organism, enabling it to cope with stressful situations and changes in the environment. In a previous study, we found that subjecting individuals of Carollia perspicillata to a chronic immobilization stress paradigm resulted in a significant increase of fecal cortisol concentrations. In the present study, we investigated the influence of stress on the behavior of C. perspicillata, by adapting a commonly used behavioral paradigm for characterizing coping styles of

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26

Ammersdörfer, Sandra, Sarah Galinski, and Karl-Heinz Esser. "Effects of aversive experience on the behavior within a custom-made plus maze in the short-tailed fruit bat, Carollia perspicillata." Journal of Comparative Physiology A 198, no. 10 (2012): 733–39. https://doi.org/10.5281/zenodo.13474535.

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(Uploaded by Plazi for the Bat Literature Project) Stress exposure evokes a variety of physiological and behavioral responses in an organism, enabling it to cope with stressful situations and changes in the environment. In a previous study, we found that subjecting individuals of Carollia perspicillata to a chronic immobilization stress paradigm resulted in a significant increase of fecal cortisol concentrations. In the present study, we investigated the influence of stress on the behavior of C. perspicillata, by adapting a commonly used behavioral paradigm for characterizing coping styles of

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27

Ammersdörfer, Sandra, Sarah Galinski, and Karl-Heinz Esser. "Effects of aversive experience on the behavior within a custom-made plus maze in the short-tailed fruit bat, Carollia perspicillata." Journal of Comparative Physiology A 198, no. 10 (2012): 733–39. https://doi.org/10.5281/zenodo.13474535.

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(Uploaded by Plazi for the Bat Literature Project) Stress exposure evokes a variety of physiological and behavioral responses in an organism, enabling it to cope with stressful situations and changes in the environment. In a previous study, we found that subjecting individuals of Carollia perspicillata to a chronic immobilization stress paradigm resulted in a significant increase of fecal cortisol concentrations. In the present study, we investigated the influence of stress on the behavior of C. perspicillata, by adapting a commonly used behavioral paradigm for characterizing coping styles of

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28

Ammersdörfer, Sandra, Sarah Galinski, and Karl-Heinz Esser. "Effects of aversive experience on the behavior within a custom-made plus maze in the short-tailed fruit bat, Carollia perspicillata." Journal of Comparative Physiology A 198, no. 10 (2012): 733–39. https://doi.org/10.5281/zenodo.13474535.

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(Uploaded by Plazi for the Bat Literature Project) Stress exposure evokes a variety of physiological and behavioral responses in an organism, enabling it to cope with stressful situations and changes in the environment. In a previous study, we found that subjecting individuals of Carollia perspicillata to a chronic immobilization stress paradigm resulted in a significant increase of fecal cortisol concentrations. In the present study, we investigated the influence of stress on the behavior of C. perspicillata, by adapting a commonly used behavioral paradigm for characterizing coping styles of

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29

Colpo, Ana C., Maria Eduarda de Lima, Marisol Maya-López, et al. "Compounds from Ilex paraguariensis extracts have antioxidant effects in the brains of rats subjected to chronic immobilization stress." Applied Physiology, Nutrition, and Metabolism 42, no. 11 (2017): 1172–78. http://dx.doi.org/10.1139/apnm-2017-0267.

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Immobilization induces oxidative damage to the brain. Ilex paraguariensis extracts (Mate) and their major natural compound, chlorogenic acid (CGA), exert protective effects against reactive oxygen species formation. Here, the effects of Mate and CGA on oxidative damage induced by chronic immobilization stress (CIS) in the cortex, hippocampus, and striatum were investigated. For CIS, animals were immobilized for 6 h every day for 21 consecutive days. Rats received Mate or CGA by intragastric gavage 30 min before every restraint session. Endpoints of oxidative stress (levels of lipid peroxidatio

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30

López-Calderón, A., C. Ariznavarreta, M. D. Calderón, J. A. F. Tresguerres, and M. I. Gonzalez-Quijano. "Role of the adrenal cortex in chronic stress-induced inhibition of prolactin secretion in male rats." Journal of Endocrinology 120, no. 2 (1989): 269–73. http://dx.doi.org/10.1677/joe.0.1200269.

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ABSTRACT The response of prolactin to chronic stress in intact, adrenalectomized and adrenomedullectomized male rats was studied. Immobilization stress in intact animals induced a significant increase in plasma concentrations of prolactin after 20 and 45 min and a significant decrease when the rats were submitted to chronic restraint (6 h daily for 4 days). Five weeks after adrenomedullectomy, plasma prolactin and corticosterone responses to chronic stress were not modified. In contrast, the inhibitory effect of chronic stress on prolactin secretion was totally suppressed by adrenalectomy. Whe

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31

Adzic, Miroslav, Jelena Djordjevic, Ana Djordjevic, et al. "Acute or chronic stress induce cell compartment-specific phosphorylation of glucocorticoid receptor and alter its transcriptional activity in Wistar rat brain." Journal of Endocrinology 202, no. 1 (2009): 87–97. http://dx.doi.org/10.1677/joe-08-0509.

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Chronic stress and impaired glucocorticoid receptor (GR) feedback are important factors for the compromised hypothalamic–pituitary–adrenal (HPA) axis activity. We investigated the effects of chronic 21 day isolation of Wistar rats on the extrinsic negative feedback part of HPA axis: hippocampus (HIPPO) and prefrontal cortex (PFC). In addition to serum corticosterone (CORT), we followed GR subcellular localization, GR phosphorylation at serine 232 and serine 246, expression of GR regulated genes: GR, CRF and brain-derived neurotropic factor (BDNF), and activity of c-Jun N-terminal kinase (JNK)

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Salehi, Azadeh, and Mahbubeh Setorki. "Effect of Hyssopus officinalis essential oil on chronic stress-induced memory and learning impairment in male mice." Bangladesh Journal of Pharmacology 12, no. 4 (2017): 448. http://dx.doi.org/10.3329/bjp.v12i4.33585.

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<p class="Abstract">The present study investigated the effect of H. officinalis essential oil on avoidance memory in chronic stress-induced. Mice were exposed to chronic immobilization stress and were treated with H. officinalis essential oil for 21 days. Memory and learning were measured using shuttle box. The serum levels of corticosterone, malondialdehyde, antioxidant capacity, brain malondialdehyde level and antioxidant capacity were measured. Treatment with 75 mg/kg of H. officinalis essential oil caused a significant increase in t2 duration under chronic stress. Serum and brain mal

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33

Павлова, Олена, and Віктор Сіренко. "THE EFFECT OF CHRONIC IMMOBILIZATION STRESS ON THE CONTENT OF MICRO- AND MACROELEMENTS IN THE PANCREAS AND BLOOD SERUM OF RATS AND THEIR NEWBORN OFFSPRING." SWorldJournal, no. 19-01 (May 30, 2023): 116–23. http://dx.doi.org/10.30888/2663-5712.2023-19-01-024.

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Have been considered the role of macro- and microelements - Ca, Mg, Zn, Fe, and Cu imbalance in the blood serum and pancreatic tissue homogenate of rats, whose pregnancy took place against the background of chronic immobilization stress and their newborn

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Sharavieva, I. L., and S. V. Gein. "Influence of different kinds of stress on apoptosis of CD4<sup>+</sup>/CD8<sup>+</sup> lymphocytes upon <i>in vivo</i> blockage of opiate receptors." Russian Journal of Immunology 24, no. 2 (2021): 203–8. http://dx.doi.org/10.46235/1028-7221-1012-iod.

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The endogenous opioid system is involved in regulation of many body functions, including immune system regulation. Endogenous opioid peptides are released under stress and communicate with opiate receptors, which are found on most immune cells. Apoptosis is one of the most important instruments in the regulation of the immune system. The aim of this study was to evaluate effects of various types of stress upon apoptosis of CD4+/ CD8+ lymphocytes under conditions of opiate receptor blockade. The objects of this study were white outbred male mice, been kept in laboratory vivarium. The following

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35

Bonaz, Bruno, and Serge Rivest. "Effect of a chronic stress on CRF neuronal activity and expression of its type 1 receptor in the rat brain." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 275, no. 5 (1998): R1438—R1449. http://dx.doi.org/10.1152/ajpregu.1998.275.5.r1438.

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The purpose of this study was to compare the effect of an acute versus a chronic immobilization stress on the genetic expression of c- fos and corticotropin-releasing factor type 1 receptor (CRF1receptor) in the paraventricular nucleus (PVN) of the rat hypothalamus. Male Sprague-Dawley rats were exposed to either a single 90-min immobilization stress or the same session for 11 consecutive days. Animals were deeply anesthetized before (control); immediately, 1.5, 3, 6, or 12 h after the acute stress; or after the last session of the repeated exposures to immobilization. Coronal frozen sections

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Mansi, J. A., and G. Drolet. "Chronic stress induces sensitization in sympathoadrenal responses to stress in borderline hypertensive rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 272, no. 3 (1997): R813—R820. http://dx.doi.org/10.1152/ajpregu.1997.272.3.r813.

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The effects of acute foot shock on cardiovascular and sympathoadrenal responses were investigated in chronically stressed borderline hypertensive rats (BHR) and Wistar-Kyoto (WKY) rats. Male BHRs were divided into two groups; the maturation group (Mat) was not stressed, whereas the chronic stress group (AJS) received 8 wk (5 days/wk, 30 min/day) of air-jet stress coupled with immobilization. After chronic stress, the rats were cannulated in the femoral artery and jugular vein. Resting mean arterial pressure (MAP), heart rate (HR), and plasma norepinephrine (NE) levels were higher in the AJS gr

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García-Fernández, María, Estela Castilla-Ortega, Carmen Pedraza, et al. "Chronic Immobilization in the malpar1Knockout Mice Increases Oxidative Stress in the Hippocampus." International Journal of Neuroscience 122, no. 10 (2012): 583–89. http://dx.doi.org/10.3109/00207454.2012.693998.

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Almeida, SA, JA Anselmo-Franci, e. AA Rosa Silva, and TL Carvalho. "Chronic intermittent immobilization of male rats throughout sexual development: a stress protocol." Experimental Physiology 83, no. 5 (1998): 701–4. http://dx.doi.org/10.1113/expphysiol.1998.sp004151.

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Marić, D., T. Kostić, and R. Kovačević. "Effects of acute and chronic immobilization stress on rat Leydig cell steroidogenesis." Journal of Steroid Biochemistry and Molecular Biology 58, no. 3 (1996): 351–55. http://dx.doi.org/10.1016/0960-0760(96)00044-1.

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Abdel Hafez, Sara Mohamed Naguib, Fatma Alzhraa Fouad Abdelbaky Allam, and Eman Elbassuoni. "Sex differences impact the pancreatic response to chronic immobilization stress in rats." Cell Stress and Chaperones 26, no. 1 (2020): 199–215. http://dx.doi.org/10.1007/s12192-020-01169-y.

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Vesna, Stojanovic, Vuckovic Nada, Barisic Nenad, and Doronjski Aleksandra. "Histopathologic changes in rat kidneys exposed to acute and chronic immobilization stress." Stress and Health 27, no. 3 (2010): e195-e198. http://dx.doi.org/10.1002/smi.1362.

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Sun, Liankang, Peng Liu, Fei Liu, et al. "Effects ofHint1deficiency on emotional-like behaviors in mice under chronic immobilization stress." Brain and Behavior 7, no. 10 (2017): e00831. http://dx.doi.org/10.1002/brb3.831.

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Bruder-Nascimento, Thiago, Dijon Henrique Salomé Campos, Carlos Alves, Samuel Thomaz, Antônio Carlos Cicogna, and Sandra Cordellini. "Effects of chronic stress and high-fat diet on metabolic and nutritional parameters in Wistar rats." Arquivos Brasileiros de Endocrinologia & Metabologia 57, no. 8 (2013): 642–49. http://dx.doi.org/10.1590/s0004-27302013000800010.

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OBJECTIVE: The aim of this study was assess the role of chronic stress on the metabolic and nutritional profile of rats exposed to a high-fat diet. MATERIALS AND METHODS: Thirty-day-old male Wistar rats (70-100 g) were distributed into four groups: normal-diet (NC), chronic stress (St), high-fat diet (HD), and chronic stress/high-fat diet (HD/St). Stress consisted at immobilization during 15 weeks, 5 times per week, 1h per day; and exposure to the high-fat diet lasted 15 weeks. Nutritional and metabolic parameters were assessed. The level of significance was 5%. RESULTS: The HD group had final

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Pastor-Ciurana, Jordi, Cristina Rabasa, Juan A. Ortega-Sánchez, et al. "Prior exposure to repeated immobilization or chronic unpredictable stress protects from some negative sequels of an acute immobilization." Behavioural Brain Research 265 (May 2014): 155–62. http://dx.doi.org/10.1016/j.bbr.2014.02.028.

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Chaouloff, F., D. Laude, D. Merino, B. Serrurier, and J. L. Elghozi. "Peripheral and central consequences of immobilization stress in genetically obese Zucker rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 256, no. 2 (1989): R435—R442. http://dx.doi.org/10.1152/ajpregu.1989.256.2.r435.

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Peripheral and central effects of acute and chronic immobilization stress were measured in lean and obese Zucker female rats. Thus hypothalamic serotonergic metabolism was analyzed by measuring the concentrations of serotonin (5-hydroxytryptamine, 5-HT), tryptophan (TRP; the precursor of 5-HT), and 5-hydroxyindoleacetic acid (5-HIAA; 5-HT metabolite). In addition, plasma total TRP, free fatty acid (FFA), insulin, and corticosterone concentrations were measured. Analysis of stress-induced changes in food consumption were also included. A single 2-h restraint stress was found to increase TRP ava

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Baek, Ji Hyeong, Soonwoong Jung, Hyeonwi Son, Jae Soon Kang, and Hyun Joon Kim. "Glutamine Supplementation Prevents Chronic Stress-Induced Mild Cognitive Impairment." Nutrients 12, no. 4 (2020): 910. http://dx.doi.org/10.3390/nu12040910.

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We recently reported that glutamine (Gln) supplementation protected glutamatergic neurotransmission from the harmful effects of chronic stress. Altered glutamatergic neurotransmission is one of the main causes of cognitive disorders. However, the cognitive enhancer function of Gln has not been clearly demonstrated thus far. Here, we evaluated whether and how Gln supplementation actually affects chronic stress-induced cognitive impairment. Using a chronic immobilization stress (CIS) mouse model, we confirmed that chronic stress induced mild cognitive impairment (MCI) and neuronal damage in the

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Petrov, N., S. Zorin, N. Biryulina, and Y. Sidorova. "PHYSIOLOGICAL AND BIOCHEMICAL EVALUATION OF THE EFFECTIVENESS OF A NEW FOOD INGREDIENT: A SOURCE OF PHYTOECDYSTEROIDS AND FLAVONOIDS FROM QUINOA GRAIN." http://eng.biomos.ru/conference/articles.htm 1, no. 19 (2021): 312–14. http://dx.doi.org/10.37747/2312-640x-2021-19-312-314.

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A new food ingredient has been developed - a source of phytoecdysteroids and flavonoids from quinoa grain. A physiological and biochemical assessment of its effectiveness under conditions of chronic immobilization stress and a single e exhausting physical activity was carried out. A pronounced adaptogenic effect of the developed food ingredient was shown.

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Kudryashov, Nikita V., T. C. Kalinina, A. A. Shimshirt, et al. "The behavioral and neurochemical aspects of the interaction between antidepressants and unpredictable chronic mild stress." Acta Naturae 12, no. 1 (2020): 63–72. http://dx.doi.org/10.32607/actanaturae.10942.

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The behavioral and neurochemical effects of amitriptyline (10 mg/kg, i.p.) and fluoxetine (20 mg/kg, i.p.) after single and chronic administration in the setting of unpredictable mild stress in outbred mice ICR (CD-1) were studied. After 28-day exposure to stress we observed an increase in depressive reactions in forced swim test in mice and decrease in serotonin (5-HT) and 5-oxyindol acetic acid (5-HIAA) levels in hippocampus, an increase in noradrenaline (NA) concentration in hypothalamus. Single and chronic administration of amitriptyline and fluoxetine led to shortening of immobilization a

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Shin, You Kyoung, Yu Shan Hsieh, Soonho Kwon, Hui Su Lee, and Geun Hee Seol. "Linalyl acetate restores endothelial dysfunction and hemodynamic alterations in diabetic rats exposed to chronic immobilization stress." Journal of Applied Physiology 124, no. 5 (2018): 1274–83. http://dx.doi.org/10.1152/japplphysiol.01018.2017.

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Although stress is one of the risk factors of diabetes, few studies have assessed the effects of stress on diabetic rats. This study, therefore, analyzed differences in cardiovascular-related factors among control, nonstressed diabetic, and stressed diabetic rats as well as assessed the effects of linalyl acetate (LA) on stressed diabetic rats. Male Sprague-Dawley rats were subjected to immobilization stress throughout the experimental period, and diabetes was induced on day 15 by a single injection of streptozotocin. After confirming the induction of diabetes, stressed diabetic rats were admi

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Li, Xiao-Hong, Jia-Xu Chen, Guang-Xin Yue, et al. "Gene Expression Profile of the Hippocampus of Rats Subjected to Chronic Immobilization Stress." PLoS ONE 8, no. 3 (2013): e57621. http://dx.doi.org/10.1371/journal.pone.0057621.

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