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Journal articles on the topic 'Chronic respiratory disorders'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

León-Velarde, Fabiola, Alberto Arregui, Manuel Vargas, Luis Huicho, and Raul Acosta. "Chronic Mountain Sickness and Chronic Lower Respiratory Tract Disorders." Chest 106, no. 1 (July 1994): 151–55. http://dx.doi.org/10.1378/chest.106.1.151.

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2

Koirala, Puru, Narendra Bhatta, Ram Hari Ghimire, Deebya Raj Mishra, Bidesh Bista, and Bhupendra Shah. "Overlap of Sleep Disorders and Chronic Respiratory Diseases: An Emerging Health Dilemma." Nepalese Medical Journal 2, no. 2 (December 22, 2019): 243–49. http://dx.doi.org/10.3126/nmj.v2i2.26007.

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Introduction: The burden of Overlap Syndrome (coexistence of sleep-related breathing disorders in patients with respiratory diseases) is high in developing countries, and such a phenomenon implies higher morbidity. The study was conducted to measure the prevalence of sleep-related breathing disorders in patients with Respiratory Symptom Complex and to identify factors associated with the severity of sleep-related breathing disorders.Materials and Methods: A hospital-based cross-sectional study of 50 patients with respiratory symptom complex was conducted at BP Koirala Institute of Health Sciences. Structured proforma and Polysomnography were used for analysis.Results: There were 24 patients (48%) with COPD, 18 (36%) with Bronchial Asthma. 6 patients (12%) with Bronchiectasis and 2 patients with Interstitial Lung Disease. 60% (n=30) patients had sleep-related breathing disorder or Overlap syndrome, 14 patients (46.67%) had mild sleep-related breathing disorder while 16 (53.33%) patients had moderate to severe type. 62.5% COPD patients, 55.55% Bronchial Asthma patients, 50% of patients with Interstitial Lung Disease and 50% Post-TB Bronchiectasis patients had a sleep-related breathing disorder. There was a significant positive correlation between the presence of sleep-related breathing disorder in patients with respiratory symptom complex and high neck circumference (0.499, p-value <0.001), waist circumference (0.293, p-value = 0.039) and hip circumference (0.371, p-value = 0.008).Conclusions: Overlap Disorders comprising sleep disorders in patients with chronic respiratory diseases are high in developing countries. Routine sleep history and polysomnography in all patients with Respiratory Symptom Complex can detect sleep-related breathing disorders.

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3

Rees, PJohn. "The management of common chronic respiratory disorders." Hamdan Medical Journal 7, no. 1 (2014): 1. http://dx.doi.org/10.7707/hmj.v7i1.317.

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4

Jung, Andreas, Irmela Heinrichs, Christian Geidel, and Roger Lauener. "Inpatient paediatric rehabilitation in chronic respiratory disorders." Paediatric Respiratory Reviews 13, no. 2 (June 2012): 123–29. http://dx.doi.org/10.1016/j.prrv.2011.08.001.

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5

Cazzola, Mario, Daiana Stolz, Paola Rogliani, and Maria Gabriella Matera. "α1-Antitrypsin deficiency and chronic respiratory disorders." European Respiratory Review 29, no. 155 (February 12, 2020): 190073. http://dx.doi.org/10.1183/16000617.0073-2019.

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α1-antitrypsin deficiency (AATD) is a hereditary disorder associated with a risk of developing liver disease and pulmonary emphysema, and other chronic respiratory disorders (mainly asthma and bronchiectasis); Z variant is the commonest deficient variant of AAT. Determining AAT concentration in serum or plasma and identifying allelic variants by phenotyping or genotyping are fundamental in the diagnosis of AATD. Initial evaluation and annual follow-up measurement of lung function, including post-bronchodilator forced expiratory volume in 1 s and gas transfer inform on disease progression. Lung densitometry is the most sensitive measure of emphysema progression, but must not be use in the follow-up of patients in routine clinical practice. The exogenous administration of purified human serum-derived AAT is the only approved specific treatment for AATD in PiZZ. AAT augmentation therapy is not recommended in PiSZ, PiMZ or current smokers of any protein phenotype, or in patients with hepatic disease. Lung volume reduction and endoscopic bronchial valve placement are useful in selected patients, whereas the survival benefit of lung transplant is unclear. There are several new lines of research in AATD to improve the diagnosis and evaluation of the response to therapy and to develop genetic and regenerative therapies and other treatments.

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Rogliani, Paola, Beatrice Ludovica Ritondo, Bartolomeo Zerillo, Maria Gabriella Matera, and Luigino Calzetta. "Drug interaction and chronic obstructive respiratory disorders." Current Research in Pharmacology and Drug Discovery 2 (2021): 100009. http://dx.doi.org/10.1016/j.crphar.2020.100009.

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7

Harrar, Dana B., Basil T. Darras, and Partha S. Ghosh. "Acute Neuromuscular Disorders in the Pediatric Intensive Care Unit." Journal of Child Neurology 35, no. 1 (September 10, 2019): 17–24. http://dx.doi.org/10.1177/0883073819871437.

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Background: The neuromuscular disorders encountered in the pediatric intensive care unit (PICU) encompass a broad spectrum of pathologies. These include acute disorders (eg, Guillain-Barre syndrome), acute-on-chronic disorders (eg, myasthenia gravis), progressive disorders (eg, muscular dystrophy), and disorders that develop in the PICU (eg, critical illness myopathy/polyneuropathy). Familiarity with the presenting features of these disorders is of paramount importance in facilitating timely diagnosis. Methods: We conducted a retrospective review of the medical records of patients admitted to the PICU or Intermediate Care Program (ICP) at a single tertiary children’s hospital from 2006 to 2017 with an acute or acute-on-chronic neuromuscular disorder. We did not include patients with a known progressive neuromuscular disorder or critical illness myopathy/polyneuropathy. Results: Twenty-four patients were admitted to the PICU/ICP with acute or acute-on-chronic neuromuscular disorders. Diagnosis and indication for ICU/ICP admission were Guillain-Barre syndrome (n = 6; respiratory failure: 3, respiratory monitoring: 2, autonomic instability: 1), myasthenia gravis (n = 5; airway clearance: 3, respiratory failure: 2), acute flaccid myelitis (n = 3; respiratory failure: 2, respiratory monitoring: 1), periodic paralysis (n = 3; intravenous potassium replacement), rhabdomyolysis (n = 3; monitoring for electrolyte derangements), infant botulism (n = 2; respiratory failure), chronic demyelinating polyneuropathy (n = 1; respiratory failure), and congenital myasthenic syndrome (n = 1; apnea). No patients were admitted to the PICU/ICP with a diagnosis of tick paralysis, acute intermittent porphyria, or inflammatory myopathy. Conclusions: Although acute and acute-on-chronic neuromuscular disorders are encountered relatively rarely in the PICU, familiarity with the presenting features of these disorders is important in facilitating timely diagnosis. This, in turn, enables the institution of effective management strategies, thereby avoiding complications associated with diagnostic delays.

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8

Adrogue, H. J., and N. E. Madias. "Influence of chronic respiratory acid-base disorders on acute CO2 titration curve." Journal of Applied Physiology 58, no. 4 (April 1, 1985): 1231–38. http://dx.doi.org/10.1152/jappl.1985.58.4.1231.

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We have recently shown that background presence of chronic metabolic acid-base disorder markedly alters in vivo acute CO2 titration curve. These studies were carried out to assess the influence of chronic respiratory acid-base disorders on response to acute hypercapnia and to explore whether the chronic level of plasma pH is the factor responsible for alterations in the CO2 titration curve. We compared whole-body responses to acute hypercapnia of dogs with preexisting chronic respiratory alkalosis (n = 8) with that of normal animals (n = 4) and animals with chronic respiratory acidosis (n = 13). Chronic respiratory alkalosis and acidosis, as well as the acute CO2 titrations, were produced in unanesthetized dogs within a large environmental chamber. For comparison with our data on chronic metabolic acidosis and alkalosis, plasma bicarbonate levels, which are secondarily altered in chronic respiratory acid-base disorders, were used as an index of chronic acid-base status of the animals. Results indicate that, as with chronic metabolic acid-base disorders, a larger increment in plasma bicarbonate occurs during acute hypercapnia when steady-state plasma bicarbonate is low (respiratory alkalosis) than when it is high (respiratory acidosis). Yet, in further analogy with the metabolic studies, plasma hydrogen ion concentration is better defended at higher plasma bicarbonate levels in accordance with mathematical relationships defined by the Henderson-Hasselbalch equation. Combined results demonstrate that the influence of chronic acid-base status on whole-body response to acute hypercapnia is independent of initial plasma pH.

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9

Faisal, Haruyuki Dewi, and Agus Dwi Susanto. "Peran Masker/Respirator dalam Pencegahan Dampak Kesehatan Paru Akibat Polusi Udara." Jurnal Respirasi 3, no. 1 (April 22, 2019): 18. http://dx.doi.org/10.20473/jr.v3-i.1.2017.18-25.

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Outdoor air pollution contributed harmful impact to public health. There are several respiratory disorders related to outdoor air pollution such as acute respiratory infection, lung cancer, asthma, chronic obstructive lung disease (COPD) and lung function disorder. Respirator is a personnel protective device which has role in the primary intervention step. Currently exist many types of respirators in industrial setting that have specific function to certain hazard exposure in work process. It is difficult to choose one type of respirator that can be implemented in population setting to protect against all air pollutant content. Therefore, it is relevant choosing one respirator type which has the ability to effectively filtrate one of air pollutant content that is the particulate matter. One respirator type, N95 mask has superiority in term of cost and technical use aspects for protecting particulate matter pollutant. Respirator usage effectivity in population setting is an important subject to find out more.

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10

Rogliani, Paola, Mario Cazzola, and Luigino Calzetta. "Cardiovascular Disease in Chronic Respiratory Disorders and Beyond." Journal of the American College of Cardiology 73, no. 17 (May 2019): 2178–80. http://dx.doi.org/10.1016/j.jacc.2018.11.068.

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11

Mane, Anil Sham Rao. "One and half year prevalence study of respiratory acidosis in acute exacerbation of chronic obstructive pulmonary disorders." Scholars Journal of Applied Medical Sciences 4, no. 7 (July 2016): 2380–84. http://dx.doi.org/10.21276/sjams.2016.4.7.16.

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12

Marrone, Oreste, Adriana Salvaggio, and Giuseppe Insalaco. "Respiratory disorders during sleep in chronic obstructive pulmonary disease." International Journal of COPD 1, no. 4 (December 2006): 363–72. http://dx.doi.org/10.2147/copd.2006.1.4.363.

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13

Currie, G. P., M. MacKenzie, and G. Douglas. "Assisted hospital discharge in patients with chronic respiratory disorders." QJM: An International Journal of Medicine 98, no. 7 (July 1, 2005): 541–42. http://dx.doi.org/10.1093/qjmed/hci082.

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14

McNicholas, Walter T., Daniel Hansson, Sofia Schiza, and Ludger Grote. "Sleep in chronic respiratory disease: COPD and hypoventilation disorders." European Respiratory Review 28, no. 153 (September 25, 2019): 190064. http://dx.doi.org/10.1183/16000617.0064-2019.

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COPD and obstructive sleep apnoea (OSA) are highly prevalent and different clinical COPD phenotypes that influence the likelihood of comorbid OSA. The increased lung volumes and low body mass index (BMI) associated with the predominant emphysema phenotype protects against OSA whereas the peripheral oedema and higher BMI often associated with the predominant chronic bronchitis phenotype promote OSA. The diagnosis of OSA in COPD patients requires clinical awareness and screening questionnaires which may help identify patients for overnight study. Management of OSA-COPD overlap patients differs from COPD alone and the survival of overlap patients treated with nocturnal positive airway pressure is superior to those untreated. Sleep-related hypoventilation is common in neuromuscular disease and skeletal disorders because of the effects of normal sleep on ventilation and additional challenges imposed by the underlying disorders. Hypoventilation is first seen during rapid eye movement (REM) sleep before progressing to involve non-REM sleep and wakefulness. Clinical presentation is nonspecific and daytime respiratory function measures poorly predict nocturnal hypoventilation. Monitoring of respiration and carbon dioxide levels during sleep should be incorporated in the evaluation of high-risk patient populations and treatment with noninvasive ventilation improves outcomes.

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15

Bugin, S., F. Lunardi, F. Bertuola, D. Snijders, L. Bottecchia, E. Perissinotto, F. Calabrese, and A. Barbato. "Pediatric chronic lower respiratory disorders: Microbiological and immunological phenotype." Pediatric Pulmonology 48, no. 8 (September 19, 2012): 780–88. http://dx.doi.org/10.1002/ppul.22677.

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16

Salamati, Payman, and Seyed mansour Razavi. "Diagnostic bronchoscopy in sulfur mustard induced chronic respiratory disorders." Burns 41, no. 7 (November 2015): 1612–13. http://dx.doi.org/10.1016/j.burns.2015.05.031.

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17

Rodriguez-Roisin, Roberto, Sonja D. Bartolome, Gérard Huchon, and Michael J. Krowka. "Inflammatory bowel diseases, chronic liver diseases and the lung." European Respiratory Journal 47, no. 2 (January 21, 2016): 638–50. http://dx.doi.org/10.1183/13993003.00647-2015.

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This review is devoted to the distinct associations of inflammatory bowel diseases (IBD) and chronic liver disorders with chronic airway diseases, namely chronic obstructive pulmonary disease and bronchial asthma, and other chronic respiratory disorders in the adult population. While there is strong evidence for the association of chronic airway diseases with IBD, the data are much weaker for the interplay between lung and liver multimorbidities. The association of IBD, encompassing Crohn's disease and ulcerative colitis, with pulmonary disorders is underlined by their heterogeneous respiratory manifestations and impact on chronic airway diseases. The potential relationship between the two most prevalent liver-induced pulmonary vascular entities,i.e.portopulmonary hypertension and hepatopulmonary syndrome, and also between liver disease and other chronic respiratory diseases is also approached. Abnormal lung function tests in liver diseases are described and the role of increased serum bilirubin levels on chronic respiratory problems are considered.

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18

Thakkar, N., R. Trivedi, P. Greenberg, and M. Ramagopal. "0958 The Prevalence of Depression in Children With Chronic Sleep and Respiratory Disorders." Sleep 43, Supplement_1 (April 2020): A364. http://dx.doi.org/10.1093/sleep/zsaa056.954.

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Abstract Introduction In 2017, 13.3% of US adolescents aged 12 to 17 had at least one major depressive episode (NIMH, 2019). The risk of depression is higher in children with sleep apnea, and children with depression or anxiety have a 1.2-1.8 times higher rate of asthma related ED visits. Therefore, the purpose of this study was to determine the prevalence of depression symptoms in children with chronic disorders. We hypothesized that subjects with sleep disorders would have a higher prevalence of positive depression scores than subjects with respiratory disease, and that the prevalence would be highest in subjects with both conditions. Methods The Patient Health Questionnaire-9 (PHQ-9) was administered to children between the ages of 12 and 18 to screen for depression as part of a pulmonary or sleep clinic visit. Each patient’s PHQ-9 results were scored as normal, mild, moderate, or severe for levels of depression severity. Additionally, a chart review was conducted to gather their demographic and clinical data. Results Of a total of 87 subjects,71 (81.6%) had a respiratory disorder and 40 (46.0%) subjects had a sleep disorder. Due to the amount of overlap of respiratory and sleep disorders amongst the subjects, depression severity rather than chronic disease was chosen as the primary outcome. Using multiple linear regression, when all other factors were held constant, the average depression score increased by 5.0 when patients had a combination of asthma and obstructive sleep apnea (p-value = 0.02) and also increased by 2.4 for subjects who were female (p-value = 0.01). Conclusion It is important to identify depression in children with chronic illness, as it can lead to higher healthcare utilization. Additionally, as mental health status may significantly impact health outcomes for patients with chronic disease, it would be beneficial to evaluate mental health in all pediatric patients with chronic disease. However, further research is needed to investigate these associations. Support None

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19

ROAD, J. D. "Assisted ventilation for chronic neuromuscular disorders." Thorax 55, no. 1 (January 1, 2000): 1–2. http://dx.doi.org/10.1136/thorax.55.1.1.

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20

Szeinbach, S. L., R. Rodriguez-Monguio, R. W. Baran, and P. B. Williams. "Sleep Disorders and Chronic Constipation: Relation to Other Co-morbidities?" Open Allergy Journal 3, no. 1 (April 28, 2010): 29–34. http://dx.doi.org/10.2174/1874838401003010029.

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Sleep disorders are common complaints and frequently associated with a number of disease states. Although the link between sleep disorders, respiratory diseases, and other co-morbid conditions experienced by patients has been investigated, the link between sleep disorders and chronic constipation is relatively unexplored. Given the widespread occurrence of sleep disorders, it is important to evaluate how sleep disorders relate to respiratory diseases and other comorbid disease states in participants with chronic constipation. Thus, the purpose of this study was to identify co-morbid conditions that were significant predictors for chronic constipation participants with and without sleep disorders. Of the 311 participants with a confirmed diagnosis of chronic constipation, 84% of the sample was female with 52% having sleep disorders, approximately two-thirds reported allergies, and 30% or less reported chronic sinusitis, chronic bronchitis, asthma, and chronic obstructive pulmonary disease (COPD). Results from logistic regression analysis revealed significant odds ratios for sleep disorders and allergies (OR 2.4; p = 0.001), asthma (OR 2.0; p = 0.01), chronic bronchitis (OR 2.2; p = 0.014), COPD (OR 4.0; p < 0.001), sinusitis (OR 2.0; p = 0.008), and for other co-morbid conditions. Perceptions of overall health were significantly worse (p < 0.001) for chronic constipation participants with certain co-morbid conditions including sleep disorders, respiratory diseases, and disease states producing pain. Co-morbid conditions may influence information provided by patients when discussing family history, diagnosing, discussing pharmacotherapy, and monitoring patient-reported outcomes. Co-morbid conditions should be considered by physicians and specialists during patient assessment and evaluation.

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Tai TC Huang, HP. "Echocardiographic assessment of right heart indices in dogs with elevated pulmonary artery pressure associated with chronic respiratory disorders, heartworm disease, and chronic degenerative mitral valvular disease." Veterinární Medicína 58, No. 12 (December 20, 2013): 613–20. http://dx.doi.org/10.17221/7180-vetmed.

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The aim of this study was to evaluate right ventricular (RV) remodeling and right heart failure associated with different causes of elevated pulmonary arterial pressure (PAP) in dogs. In total, 169 client-owned dogs with tricuspid regurgitation (TR) and 40 client-owned clinically healthy dogs were included. Dogs with TR were further categorised as suffering from chronic respiratory disorders (CRD), heartworm disease (HWD), mild/moderate chronic degenerative mitral valvular disease (CDMD), and severe CDMD. Among the echocardiographic indices of the right heart, no significant difference in the tricuspid annular plane systolic excursion to aortic root diameter ratio was found among the clinical healthy controls and the four different TR categories. No significant differences in TR peak velocity and pulmonic regurgitation peak velocity were found among dogs in the four different TR categories. The ratio of the right to left ventricular basal diameter in the right ventricular-focused view was significantly higher in dogs with chronic respiratory disorders and dogs with heartworms. Left ventricular compression quantified using the eccentricity index and the ratio of the main pulmonary artery to aortic root diameter were significantly higher in dogs with HWD. Their right ventricular acceleration to ejection time (AT/ET) was significantly lower in dogs with HWD. Based on these findings, we conclude that right heart indices are affected by CRD, HWD, and moderate to severe CDMD. However, right heart indices derived from left heart measurements might be underestimated in dogs with CDMD.

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22

Pelton, Stephen I., Rotem Lapidot, Matthew Wasserman, Melody Shaff, Ahuva Hanau, Alexander Lonshteyn, and Derek Weycker. "1510. Infant Pneumonia and Subsequent Risk of Chronic Respiratory Disorders." Open Forum Infectious Diseases 7, Supplement_1 (October 1, 2020): S758—S759. http://dx.doi.org/10.1093/ofid/ofaa439.1691.

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Abstract Background Community-acquired pneumonia (CAP) in infancy (i.e., among children aged < 2 years) may have long-term consequences for the rapidly developing lung. We examined the impact of pneumonia in infancy on subsequent respiratory health. Methods A retrospective matched-cohort design and data from Optum’s de-identified Integrated Claims-Clinical dataset (2009-2018) were employed. Study population comprised children who were hospitalized for CAP before age 2 years (“CAP patients”) as well as matched comparators without evidence of pneumonia before age 2 years (“comparison patients”). CAP patients and comparison patients were matched (fixed 1:5 ratio, without replacement) using estimated propensity scores and a nearest-neighbor approach; those with evidence of selected medical conditions (e.g., extreme prematurity, congenital diseases, respiratory diseases) before age 2 years were excluded. Study outcomes included recurrent pneumonia and a composite of asthma, recurrent wheezing, and hyperactive airway disease. Rates of study outcomes from age 2 to 5 years were estimated for all CAP and comparison patients as well as subgroups of CAP patients (and corresponding comparison patients) stratified by etiology (bacterial, viral, unspecified). Results Study population totaled 1,343 CAP patients and 6,715 comparison patients. CAP patients and comparison patients were well-balanced on their baseline characteristics and mean duration of follow-up was 757 and 729 days, respectively. Rates of chronic respiratory disorders from age 2 to 5 years were significantly higher among CAP patients versus comparison patients. Analyses of subgroups stratified by etiology demonstrated higher rates of study outcomes among CAP patients across all strata. Rates of recurrent pneumonia and a composite of asthma, recurrent wheezing, and hyperactive airway disease from age 2 to 5 years among CAP patients and matched comparison patients Conclusion Infant CAP foreshadows an increase in subsequent risk of chronic respiratory disorders. Further studies are needed to determine whether this elevated risk is due to infant pneumonia or whether infant pneumonia is a marker of at-risk children. Disclosures Stephen I. Pelton, MD, Merck vaccine (Consultant, Grant/Research Support)Pfizer (Consultant, Grant/Research Support)Sanofi Pasteur (Consultant, Other Financial or Material Support, DSMB)Seqirus Vaccine Ltd. (Consultant) Rotem Lapidot, MD, MSCI, Pfizer (Consultant) Matthew Wasserman, MSc., Pfizer Inc. (Employee) Melody Shaff, BA, Pfizer, Inc. (Consultant, Grant/Research Support, Scientific Research Study Investigator, Research Grant or Support) Ahuva Hanau, BS, Pfizer, Inc. (Consultant, Grant/Research Support, Scientific Research Study Investigator, Research Grant or Support) Alexander Lonshteyn, PhD, Pfizer, Inc. (Consultant, Grant/Research Support, Scientific Research Study Investigator, Research Grant or Support) Derek Weycker, PhD, Pfizer Inc. (Consultant, Grant/Research Support, Scientific Research Study Investigator, Research Grant or Support)

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Vincken, Walter, Murray G. Elleker, and Manuel G. Cosio. "Determinants of respiratory muscle weakness in stable chronic neuromuscular disorders." American Journal of Medicine 82, no. 1 (January 1987): 53–58. http://dx.doi.org/10.1016/0002-9343(87)90377-9.

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24

Sharma, Nitesh. "The Yoga for physical and mental health – Can possibly aid in prevention and management of COVID19 infection?" Dev Sanskriti Interdisciplinary International Journal 16 (July 31, 2020): 22–31. http://dx.doi.org/10.36018/dsiij.v16i.161.

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COVID19 pandemic is global infectious disease caused by SARS Corona Virus 2. The pandemic so far has affected more than 200 countries and territories causing more than 12,552,765 human infections and 561,617 human deaths. The situation has created global emergency crisis and is rapidly spreading. The infected humans are known to have low immunity and once infected developed conditions such as acute respiratory distress syndrome, breathlessness, severe dyspnea, tachypnea, respiratory distress, hypoxia and cardiac arrest, etc. In addition, people with chronic diseases like diabetes, hypertension, cardiovascular disorders, Chronic obstructive pulmonary disorder (COPD), asthma, and elderly people with weakened immune systems are known to be more prone to catch the infection. So far no treatment is clinically proven and available, but many are under investigations; the best approach to fight against the disease is prevention and management of COVID19 infection. Yoga, meditation, and yogic bio-cleansing practices previously evidenced for general immune boosting capacity, and are also evidenced for the management of respiratory disorders, non-communicable disorders such as diabetes, cardiovascular diseases, etc, and also for psychological disorders and ailments; by reviewing these studies, in the presented study, it was attempted to shed a light on the possibility of supporting role of Yoga for improving physical and mental health in the patients with COVID19 with respiratory disorders, co-morbidities (diabetes and cardiovascular disorders), decreased immune function, and psychological illness.

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Andreev, Viktor, Alexander Fominikh, Igor Konovalov, Alexander Morozov, and Alina Snegireva. "COMPARATIVE STUDY OF THE FUNCTIONAL STATE OF CARDIORESPIRATORY SYSTEM AND PHYSICAL FITNESS OF SCHOOLCHILDREN AGED 13 TO 16 YEARS WITH CHRONIC RESPIRATORY DISORDERS AND THEIR HEALTHY PEERS." SCIENCE AND SPORT: current trends 8, no. 4 (December 1, 2020): 33–39. http://dx.doi.org/10.36028/2308-8826-2020-8-4-33-39.

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Purpose of research. Comparative study of the cardiorespiratory activity and physical fitness of schoolchildren aged 13 to 16 years with chronic respiratory disorders and their healthy peers. Methods and organization of research. The research process included the following methods: analysis of scientific and methodological literature with subsequent systematization of data, pedagogical observation, functional tests, pedagogical testing, anthropometric measurements, and mathematical statistics. Research results and discussion. This article contains the findings of a study investigating cardiorespiratory system and physical fitness of both male and female schoolchildren aged 13 to 16 years with chronic respiratory disorders. We carried out a comparative analysis of the obtained indicators of studied children and their peers without health problems. We applied the functional tests determining the activity of cardiorespiratory system to identify adaptive capacities of children to physical exercise. We used special tests to assess physical fitness. The study revealed that the cardiorespiratory activity and physical fitness levels of schoolchildren with chronic respiratory disorders are lower than the same parameters of their peers without health problems. Conclusion. Educational research aimed at investigating the functional state of cardiorespiratory system and physical fitness of schoolchildren with chronic respiratory disorders and their healthy peers revealed that the indicators of cardiorespiratory activity of schoolchildren with chronic respiratory disorders are significantly lower than the same parameters of their healthy peers.

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Geltser, B. I., I. G. Kurpatov, and V. N. Kotelnikov. "Respiratory muscle dysfunction and chronic obstructive pulmonary disease." Clinical Medicine (Russian Journal) 96, no. 7 (December 15, 2018): 581–89. http://dx.doi.org/10.18821/0023-2149-2018-96-7-581-589.

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The review presents literature data on the problem of respiratory muscle (RM) dysfunction in patients with chronic obstructive pulmonary disease (COPD). In the development of RM dysfunction, both local and systemic factors of the pathogenesis of COPD are important. Local factors are associated with lung remodelling and the need to overcome RM excessive breathing resistance, which increases the intensity of their work, contributes to the development of hypertrophy and insufficiency. Chronic systemic inflammation, oxidative stress, excessive proteolysis and other systemic manifestations of COPD change the metabolism and structural and functional organisation of RM. Low nutritional status, increasing protein-energy deficiency, electrolyte imbalance, endocrine disorders against the background of progressive respiratory insufficiency and tissue hypoxia contribute to the development of RM weakness. The combination of COPD, acute disorders of cerebral circulation and chronic heart failure sharply worsens the function of RM and the prognosis of comorbid diseases. Also, the dysfunction of RM in patients with COPD is significantly aggravated at the age of senility. The review discusses the possibilities of pharmacological correction of RM dysfunction and other clinical aspects of this problem.

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Luzhetsky, Konstantin P., Ol’ga Yu Ustinova, Svetlana S. Kleyn, Dmitrii N. Koshurnikov, Svetlana S. Vekovshinina, and Vladimir M. Chigvintsev. "Complex evaluation of health state of population residing under combined exposure to noise and chemical risk factors caused by activities of major airport hub." Occupational Health and Industrial Ecology, no. 10 (February 18, 2019): 12–16. http://dx.doi.org/10.31089/1026-9428-2018-10-12-16.

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Complex evaluation covered health state of population residing under combined exposure to physical (noise) and chemical (manganese, formaldehyde, phenol, benzene) risk factors caused by airport activities. Findings are unacceptable chronic risks expressed through risk index for development of nervous system diseases (HI=9.45–51.75), respiratory disorders (HQ=2,62–6,95) and immune system ailments (HQ=1,75–4,23). In children, functional disorders of nervous system (parasympathetic type vegetative dystonia) and respiratory organs (chronic disorders of upper respiratory tract) are diagnosed 1,5–1,8 times higher than those in the reference group; over 5% of children aged 4–7 years demonstrate bilateral conductive deafness. Reliable cause-effect relationships were revealed between functional nervous system disorders (parasympathetic type vegetative dystonia, astheno-neurotic syndrome, vascular cephalgia, sleep disorders) and increased serum level of manganese and benzene (proportion of explained dispersion, R2=0,55–0,87, 26,44≤F≥389,54), between respiratory diseases (chronic rhinitis, chronic pharyngitis) and increased serum level of formaldehyde (R2=0,73–0,91; 350,8≤F≥778,3), with high statistic significance (p < 0,0001). For sanitary epidemiologic examination purposes, case-based reasoning for relationships of children health disorders, management decisions, the authors suggested and justified a list of parameters for negative combined impact of risk factors caused by airport hub.

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Singh, Meenu, and Nidhi Anil. "Nitric oxide: A promising biomarker for respiratory disorders." Journal of Pediatric Biochemistry 01, no. 04 (December 2010): 325–29. http://dx.doi.org/10.1055/s-0036-1586383.

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AbstractNitric oxide (NO) is a ubiquitous messenger molecule with multiple roles in cellular physiology and signaling. Recent studies have indicated the role of NO as an inflammatory mediator and as a potential non invasive biomarker. The current review focuses on the role of nitric oxide and its derivatives including nitrites as potential non invasive biomarkers for assessing airway inflammation in respiratory disorders including asthma, bronchiectasis, cystic fibrosis and chronic obstructive pulmonary disease.

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Scott, Kate M., Mark A. Oakley Browne, Magnus A. Mcgee, and J. Elisabeth Wells. "Mental-Physical Comorbidity in Te Rau Hinengaro: The New Zealand Mental Health Survey." Australian & New Zealand Journal of Psychiatry 40, no. 10 (October 2006): 882–88. http://dx.doi.org/10.1080/j.1440-1614.2006.01907.x.

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Objective: To estimate the prevalence of chronic physical conditions, and the risk factors for those conditions, among those with 12 month mental disorder; to estimate the prevalence of 12 month mental disorder among those with chronic physical conditions. Method: A nationally representative face-to-face household survey was carried out in October 2003 to December 2004 with 12 992 participants aged 16 years and over, achieving a response rate of 73.3%. Mental disorders were measured with the World Mental Health version of the Composite International Diagnostic Interview (CIDI 3.0). Physical conditions were self-reported. All associations are reported adjusted for age and sex. Results: People with (any) mental disorder, relative to those without mental disorder, had higher prevalences of several chronic physical conditions (chronic pain, cardiovascular disease, high blood pressure and respiratory conditions) and chronic condition risk factors (smoking, overweight/obesity, hazardous alcohol use). Around a quarter of people with chronic physical conditions had a comorbid mental disorder compared with 15% of the population without chronic conditions. Significant relationships occurred between some mental disorders and obesity, cardiovascular disease and diabetes for females, but not for males. Conclusions: This paper provides evidence of substantial comorbidity between mental disorders and chronic physical conditions in New Zealand. This should be borne in mind by clinicians working in both mental health and medical services.

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Bowen, RC, A. Senthilselvan, and A. Barale. "Physical Illness as an Outcome of Chronic Anxiety Disorders." Canadian Journal of Psychiatry 45, no. 5 (June 2000): 459–64. http://dx.doi.org/10.1177/070674370004500506.

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Background: The literature indicates increased rates of some medical conditions in patients with anxiety disorders. We used the Saskatchewan Health databases to examine the development of nonpsychiatric medical diseases in patients with anxiety disorders. This study has a large population base, and the Saskatchewan health plan does not limit the provision of services to this populaiton. Method: We observed the annual incidence of specified medical conditions in patients with anxiety disorders and in control subjects over a 10-year period. Subjects in both groups had not been treated for the specified medical conditions before the start of the observation period. Results: The anxiety cohort had a significantly higher relative risk of developing medical diseases compared with the control group. The highest relative risk, indicated by the hazard ratio, was for cerebrovascular disease (hazard ratio 2, 95% CI 1.09–3.65). Hazard ratios were significant for cerebrovascular disease and atherosclerosis as well as for ischemic heart, gastrointestinal, hypertensive, and respiratory diseases. Conclusions: This study provides additional evidence for an association between anxiety disorder and the later development of medical morbidity.

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Argjiri, Dh, S. Bala, F. Gradica, A. Mezini, L. Agolli, V. Miha, V. Selmani, O. Nuredini, and Y. Vakeflliu. "Pulmonary Rehabilitation - PR." Albanian Journal of Trauma and Emergency Surgery 2, no. 1 (January 20, 2018): 61–66. http://dx.doi.org/10.32391/ajtes.v2i1.159.

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Chronic respiratory diseases are associated with severe, not only pulmonary, but also systemic damage such as dysfunction of peripheral muscles, dysfunction of respiratory muscles, nutritional disorders, cardiac injuries, skeletal disorders, sensory debilities, and psychological dysfunction. Mechanisms of these injuries are many and different. Pulmonary recovery (PR) is an integral part of clinical therapy in patients with chronic respiratory disease who continue to be symptomatic or continue to have pulmonary function depression, regardless of standard medical treatment.

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Elgarov, Anatoliy A., M. A. Kalmykova, and M. A. Elgarov. "Respiratory sleep disorders in vehicle drivers." Clinical Medicine (Russian Journal) 94, no. 5 (June 20, 2016): 374–78. http://dx.doi.org/10.18821/0023-2149-2016-94-5-374-378.

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Aim: to determine the frequency of respiratory sleep disorders (RSD) in vehicle drivers, peculiarities of their clinical status and workability. Material and methods. The study included the main group of 106 vehicle drivers (VD) and control group of 104 of subjects of other professions. The following methods were used: fibrooptic endoscopy, standard questionnaire, pulsoxymetry, 24 hour blood pressure and ECG monitoring, psychophysiological testing of 86 VD with RSD, arterial hypertension with and without complications. Results. The clinical and instrumental signs of RSD were found in 65.1% VD of the main group and 47,1% of controls. Transitory ischemic attacks, cardiac arrhythmias and their combination occurred more frequently in VD (82.6, 59.2, and 52.2% respectively) than in controls (51.0, 44.8, and 32.6%). In most observations of VD, the smoking rate (98.1%), alcohol intake (95.3%), increased body mass (74.5%), obese (21,7%) dyslypoproteidemia (73.6%), left ventricular hypertrophy (54.7%) and arterial hypertension (57.5%) were significantly higher than in controls : S (76.9%), AI (75.0%), IBM (56.7%), O (18.3%), DLP (59.6%), LVH (41.3%), AH (39.4%). Chronic obstructive pulmonary diseases was diagnosed in 55.6% of VD and 51.9% of controls, diabetes mellitus in 34.9% and 20.2%, epidemiological forms of ischemic heart disease in 22.6% VD and 20.2% controls. Psychophysilogical testing of VD group revealed deterioration of professional qualities and functions of the drivers with respiratory sleep disorders. Conclusion. Significant frequency of RSD among VD (65.1%) in comparison with subjects of other professions (47.1%) was documented. RSD cause deterioration ofprofessional abilities of VD which increases the risk of traffic accidents.

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Bruno, C. M. "Analysis of Acid-Base Disorders in Patients With Chronic Respiratory Failure." Respiratory Care 56, no. 3 (March 1, 2011): 366. http://dx.doi.org/10.4187/respcare.01201.

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Guerin, C. "Analysis of Acid-Base Disorders in Patients With Chronic Respiratory Failure." Respiratory Care 56, no. 3 (March 1, 2011): 368. http://dx.doi.org/10.4187/respcare.01214.

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Berend, K., and R. Engels. "Analysis of Acid-Base Disorders in Patients With Chronic Respiratory Failure." Respiratory Care 56, no. 3 (March 1, 2011): 367–68. http://dx.doi.org/10.4187/respcare.01218.

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Cook-Sather, Scott D., and John J. Downes. "3 Anaesthesia for infants and children with chronic respiratory system disorders." Baillière's Clinical Anaesthesiology 10, no. 4 (December 1996): 633–55. http://dx.doi.org/10.1016/s0950-3501(96)80040-7.

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WARD, M., H. JAVITZ, W. SMITH, and M. WHAN. "Lost income and work limitations in persons with chronic respiratory disorders." Journal of Clinical Epidemiology 55, no. 3 (March 2002): 260–68. http://dx.doi.org/10.1016/s0895-4356(01)00468-1.

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Rochester, Carolyn L., Carl Fairburn, and Rebecca H. Crouch. "Pulmonary Rehabilitation for Respiratory Disorders Other than Chronic Obstructive Pulmonary Disease." Clinics in Chest Medicine 35, no. 2 (June 2014): 369–89. http://dx.doi.org/10.1016/j.ccm.2014.02.016.

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Maslyanyuk, Natal’ya Anatol’yevna, and Inna Ivanovna Evsyukova. "Elective caesarean section and the risk of respiratory distress in preterm infants." Journal of obstetrics and women's diseases 64, no. 4 (September 15, 2015): 49–56. http://dx.doi.org/10.17816/jowd64449-56.

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The incidence of respiratory disorders and their risk factors in 349 full-term newborns, extracted by planned cesarean section at various stages of pregnancy. It was found that respiratory disorders (transient tachypnea) observed in 16.5 % of newborns, gestational age of 37 weeks, 4.6% - 38 weeks and 1.6% - ≥39 weeks. The risk of respiratory disorders in children whose mothers have a combination of chronic functional systems (gastrointestinal tract, cardiovascular system, respiratory system) and pregnancy complication preeclampsia mild.

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Dayan, Yaron Bar, Keren Elishkevits, Liav Goldstein, Avishay Goldberg, Michel Fichler, Nisim Ohana, Yehezkel Levi, and Yosefa Bar Dayan. "Screening for Common Respiratory Diseases among Israeli Adolescents." Canadian Respiratory Journal 11, no. 4 (2004): 298–300. http://dx.doi.org/10.1155/2004/529510.

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BACKGROUND:Respiratory diseases are responsible for a significant proportion of serious morbidity among adolescents. There are few reports on the prevalence of common respiratory disorders in this population. The previous studies focused on specific diseases and screened relatively small samples.OBJECTIVE:To define the prevalence of different common respiratory disorders among 17-year-old Israeli conscripts.DESIGN:All 17-year-old Israeli nationals are obliged by law to appear at the Israel Defense Forces recruiting office for medical examination. Respiratory disease specialists evaluated and classified nominees with suspected respiratory disorders.RESULTS:A high prevalence of respiratory morbidity was found among 94,805 17-year-old conscripts (61.5% male, 39.5% female). The most prevalent diagnosis was asthma (in 8% of male and 6.8% of female subjects). Fifty-five per cent of the asthma patients suffered from moderate to severe disease. The prevalence of chronic obstructive pulmonary disease was 0.03% for the male and 0.01% for the female subjects. A difference in morbidity patterns between male and female adolescents was noted, particularly in the prevalence of chest deformation and spontaneous pneumothorax.CONCLUSIONS:The most prevalent respiratory disorder among 17-year-old Israeli conscripts was asthma. One-half of the asthma patients in this study suffered from moderate to severe disease. The prevalence of other respiratory disorders was much lower.

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Minghelli, Beatriz, Raul Oliveira, and Carla Nunes. "Association of obesity with chronic disease and musculoskeletal factors." Revista da Associação Médica Brasileira 61, no. 4 (August 2015): 347–54. http://dx.doi.org/10.1590/1806-9282.61.04.347.

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SummaryIntroduction:overweight and obesity in adolescents are major public health problems with particular interest, because of their potential association with risk factors for development of diseases. The study aimed to determine the prevalence of overweight and obesity in adolescents in southern Portugal and investigate the association with risk factors for development of cardiovascular, respiratory and musculoskeletal diseases.Methods:the sample consisted of 966 adolescents aged 10 to 16 years. The calculation of body mass index (BMI), evaluation of blood glucose, total cholesterol and triglycerides, blood pressure, spirometry and application of low back pain (LBP) questionnaire were performed.Results:178 (18.4%) adolescents were overweight and 52 (5.4%) obese. None of the variables revealed a statistically significant association with overweight and obesity. The presence of high blood pressure was observed in 200 (20.7%) individuals and hypertension in 158 (16.4%) adolescents. Overweight and obese adolescents are 2.3 times more likely to develop signs of pre-hypertension and hypertension. 559 (57.9%) students had restrictive respiratory disorders and 23 (2.4%) had obstructive disorders. Those who were overweight and obese had 0.64 probability of having restrictive respiratory disorders.Conclusion:there was a high prevalence of overweight and obesity in Portuguese adolescents and these showed a statistically significant relationship with the development of pre-hypertension and hypertension, and restrictive respiratory disorders.

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Chebbo, Mohamad, Catherine Duez, Marie C. Alessi, Pascal Chanez, and Delphine Gras. "Platelets: a potential role in chronic respiratory diseases?" European Respiratory Review 30, no. 161 (September 15, 2021): 210062. http://dx.doi.org/10.1183/16000617.0062-2021.

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Platelets are small anucleate cells known for their role in haemostasis and thrombosis. In recent years, an increasing number of observations have suggested that platelets are also immune cells and key modulators of immunity. They express different receptors and molecules that allow them to respond to pathogens, and to interact with other immune cells. Platelets were linked to the pathogenesis of some inflammatory disorders including respiratory diseases such as asthma and idiopathic pulmonary fibrosis. Here, we discuss the involvement of platelets in different immune responses, and we focus on their potential role in various chronic lung diseases.

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Tsai, Sheila C. "Chronic obstructive pulmonary disease and sleep related disorders." Current Opinion in Pulmonary Medicine 23, no. 2 (March 2017): 124–28. http://dx.doi.org/10.1097/mcp.0000000000000351.

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Adir, Y., and M. Humbert. "Pulmonary hypertension in patients with chronic myeloproliferative disorders." European Respiratory Journal 35, no. 6 (May 31, 2010): 1396–406. http://dx.doi.org/10.1183/09031936.00175909.

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Vögele, Claus, and Andreas von Leupoldt. "Mental disorders in chronic obstructive pulmonary disease (COPD)." Respiratory Medicine 102, no. 5 (May 2008): 764–73. http://dx.doi.org/10.1016/j.rmed.2007.12.006.

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Adir, Yochai, Davide Elia, and Sergio Harari. "Pulmonary hypertension in patients with chronic myeloproliferative disorders." European Respiratory Review 24, no. 137 (August 31, 2015): 400–410. http://dx.doi.org/10.1183/16000617.0041-2015.

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Pulmonary hypertension (PH) is a major complication of several haematological disorders. Chronic myeloproliferative diseases (CMPDs) associated with pulmonary hypertension have been included in group five of the clinical classification for pulmonary hypertension, corresponding to pulmonary hypertension for which the aetiology is unclear and/or multifactorial. The aim of this review is to discuss the epidemiology, pathogenic mechanism and treatment approaches of the more common forms of pulmonary hypertension in the context of CMPD's: chronic thromboembolic pulmonary hypertension, precapillary pulmonary hypertension and drug-induced PH.

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Shah, Dolly, and Anjali Bhise. "Effect of Pulmonary Rehabilitation Training in Non-, Ex- and Current Smokers with Chronic Respiratory Disorders by the Measurement of Functional Capacity: A Pilot Study." International Journal of Health Sciences and Research 11, no. 8 (August 6, 2021): 48–60. http://dx.doi.org/10.52403/ijhsr.20210808.

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Title: Effect of Pulmonary Rehabilitation Training in Non-, Ex- and Current Smokers with Chronic Respiratory Disorders by the measurement of Functional Capacity: A Pilot Study Background: Earlier research shows efficacy of pulmonary rehabilitation in chronic lung disorders with regards to their smoking status, but not in all 3 groups together (i.e. Ex-,Never- and Current smokers). So, the goal is to find out effectiveness of pulmonary rehabilitation in chronic lung disorders with regard to their smoking status by the measurement of 6 minute walk distance. This study will help in identifying least benefited to most benefited group among 3 groups by pulmonary rehabilitation . Methodology : Total 15 patients of both gender and age 30-80 years were randomly selected and divided into 3 groups: Non-, Ex- and Current Smokers with Chronic Respiratory Disorders. Pulmonary Rehabilitation was given for 8 weeks, 3 times / week (30-40 minutes). Pre and Post PR (After 8 weeks), functional capacity was measured by 6 minute walk distance. Data was analyzed by SPSS (v16.0) - One way ANOVA to compare 3 groups and Post Hoc tests to detect the intergroup differences . Results: Pulmonary Rehabilitation was effective in all 3 groups and Functional Capacity of all patients was improved (p<0.05). Effectiveness of Pulmonary Rehabilitation was more in Non- Smokers compared to Current Smokers. (p<0.05) Conclusion: Effectiveness of Pulmonary Rehabilitation was significant in all smokers with chronic respiratory disorders but Non- Smokers were more benefited from Current Smokers due to their non-smoking status. These findings emphasized effectiveness of Pulmonary Rehabilitation and benefits of non-smoking status among patients with chronic respiratory disorders. So, we must encourage measures for smoking cessation at earliest in pulmonary rehabilitation program . Key words: Functional Capacity, 6 Minute Walk Distance, Pulmonary Rehabilitation, Smokers.

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Ledgerwood, L. G., and P. C. Belafsky. "Chronic non-granulomatous supraglottitis: a rare and difficult disease." Journal of Laryngology & Otology 126, no. 8 (May 29, 2012): 854–57. http://dx.doi.org/10.1017/s0022215112000977.

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AbstractObjectives:To examine chronic non-granulomatous supraglottitis, a rare disorder of uncertain aetiology with few reported cases in the literature.Case reports:We describe two cases of chronic non-granulomatous supraglottitis that led to persistent respiratory compromise. Patients underwent extensive investigation that failed to reveal a definitive diagnosis.Conclusion:In patients suffering from chronic inflammation of the supraglottic larynx without evidence of infection, neoplasm or granulomatous disease, many disorders must be ruled out in order to diagnose chronic non-granulomatous supraglottitis, which is a diagnosis of exclusion. We review the literature on this rare entity, discuss current management strategies, and suggest an algorithm for diagnostic investigation.

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McCall, W. Vaughn. "The Treatment of Comorbid Insomnia." CNS Spectrums 14, S13 (December 2009): 10–12. http://dx.doi.org/10.1017/s1092852900003965.

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There are many new findings in the area of comorbid insomnia. Almost 50% of all cases of chronic insomnia are due to a mental disorder, with depressive illness explaining the majority of cases related to mental disorder (Slide 1). Other common causes of comorbid, or secondary, insomnia include chronic respiratory disease such as asthma and chronic obstructive pulmonary disease, chronic pain, degenerative neurological disease, and some medications such as glucocorticoids and serotonin reuptake inhibitors. A general principle of management of insomnia related to mental or medical disorders is that the principal disorder must be fully treated as part of the insomnia treatment plan. If there is an offending medication, it must be discontinued if possible.

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Fukuda, Yosuke, Tetsuya Homma, Shintaro Suzuki, Takahiro Takuma, Akihiko Tanaka, Takuya Yokoe, Tsukasa Ohnishi, Yoshihito Niki, and Hironori Sagara. "High burden of Aspergillus fumigatus infection among chronic respiratory diseases." Chronic Respiratory Disease 15, no. 3 (March 8, 2018): 279–85. http://dx.doi.org/10.1177/1479972318761654.

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Aspergillus fumigatus (AF) is a ubiquitous fungus in our environment and causes severe airway disorders. Chronic respiratory diseases (CRDs) are a series of chronic airway and lung diseases. Although both are chronic disorders, however, the relationships between AF and CRDs are still unclear. Therefore, we examined 104 Aspergillus species (spp.) isolated samples in our hospital during three consecutive years to further elucidate the relationships between Aspergillus spp. and CRDs. Based on sample isolates, we then grouped these into two groups, AF and non-AF, to retrospectively analyse the clinical features and to clarify the relationships between AF and CRDs. Importantly, the manifestation of CRD was more frequent in the AF group than in the non-AF group ( p = 0.035). Among CRDs, lung fibrosis was more evident in the AF group ( p = 0.025). Moreover, diabetes mellitus was tended to be evident in AF group than non-AF group ( p = 0.035). In conclusion, CRDs, especially lung fibrosis, were highly prevalent in AF group than non-AF group.

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