Academic literature on the topic 'Chronomodulated drug delivery system'

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Journal articles on the topic "Chronomodulated drug delivery system"

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Arora, Shilpi, and Sonia Dhiman. "Formulation Development and Evaluation of Chronomodulated Drug Delivery Systems for treatment of Diabetes." Journal of Neonatal Surgery 14, no. 19S (2025): 381–93. https://doi.org/10.63682/jns.v14i19s.4772.

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The research focuses on the formulation development and evaluation of chronomodulated drug delivery systems for anti diabetic drugs, leveraging insights from past studies to optimize the delivery of Vildagliptin microspheres. Chronomodulated drug delivery systems are designed to synchronize the release of medication with the body's natural biological rhythms, enhancing therapeutic efficacy and patient compliance. Vildagliptin microspheres were meticulously prepared using an emulsion solvent evaporation method, guided by previous findings on drug-polymer ratios, surfactant concentrations, and s
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Alekya, Thota, Dudhipala Narendar, Donthi Mahipal, Narala Arjun, and Banala Nagaraj. "Design and Evaluation of Chronomodulated Drug Delivery of Tramadol Hydrochloride." Drug Research 68, no. 03 (2017): 174–80. http://dx.doi.org/10.1055/s-0043-119072.

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AbstractRheumatoid arthritis is an auto immune disease which requires chronotherapy as it occurs during early morning. Tramadol hydrochloride (TH) is an analgesic drug, used to treat rheumatoid arthritis. The aim of the present investigation was to develop chronomodulated drug delivery system of tramadol hydrochloride such that it releases the drug early in the morning, during which the symptoms of rheumatoid arthritis worsen. To develop chronomodulated drug delivery system of TH, initially core tablets of TH were prepared using three different supradisintegrants followed by coating with pH de
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P, Mahalakshmi, Suriyaprakash T N K, and S. Lakshmana Prabu. "Chronomodulated Delivery of Pantoprazole for Nocturnal Hyperacidity." International Journal of Pharmaceutical Sciences and Nanotechnology 8, no. 4 (2015): 3038–44. http://dx.doi.org/10.37285/ijpsn.2015.8.4.7.

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The objective of this work was to design and evaluate an oral site-specific, pulsatile drug delivery system containing Pantoprazole sodium which can be targeted to colon in a pH and time dependent manner, to modulate the drug level in synchrony with the circadian rhythm of nocturnal hyperacidity. Five different composition of Core tablets were prepared by direct compression technique. Based on the release studies of core tablets, nine different compositions of press coated tablets were prepared and analyzed. The press coated tablet further coated by using five different proportions of Eudragit
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V, Ravali, and P. Balaji. "Pulsatile Drug Delivery Systems: A Comprehensive Review." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 01 (2024): 463–71. http://dx.doi.org/10.25258/ijddt.14.1.65.

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sigmoidal drug release profile is formed when a pulsatile drug delivery system (PDDI) initiates drug administration and follows it up with rapid and complete drug release. It ensures the correct dosage of the drug is delivered at the right time and place. Pulsatile drug delivery is effective for treating asthma, arthritis, cancer, diabetes, epilepsy, hypertension, ulcers, and hypercholesterolemia, among others. There are many types of delivery systems in the pharmaceutical industry, including capsular, osmotic, single and multi-unit designs and membranes that are soluble and erodible. Innovati
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Patil, ArchanaS, VinayakS Masthiholimath, BasavarajK Najwade, PanchaxariM Dandagi, and AnandP Gadad. "Development and characterization of chronomodulated drug delivery system of captopril." International Journal of Pharmaceutical Investigation 1, no. 4 (2011): 227. http://dx.doi.org/10.4103/2230-973x.93010.

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Amitha, Shetty 1. *. Panneer Selvam 2. Maya Sharma 3. Smitha Shetty 4. "FORMULATION AND EVALUATION OF CHRONOMODULATED DRUG DELIVERY SYSTEM CONTAINING CAPTOPRIL AND HYDROCHLOROTHIAZIDE." Journal of Pharma Research 8, no. 7 (2019): 468–77. https://doi.org/10.5281/zenodo.3357189.

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<strong><em>ABSTRACT</em></strong> <strong><em>B</em></strong><em>lood pressures displays circadian rhythm. The objective of present study was to develop chronomodulated drug delivery system containing Captopril and Hydrochlorothiazide to achieve extended retention in upper gastro intestinal tract to enhance absorption and bioavailability. Captopril mucoadhesive microspheres were prepared by emulsification method using sodium alginate and guar gum polymers whereas Hydrochlorothiazide floating microspheres were prepared by non-aqueous solvent evaporation method using ethyl cellulose and hydroxy
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Raghavender, Chenna 1. *. Y. Padmanabha Reddy 2. "FORMULATION AND EVALUATION OF CHRONOMODULATED DRUG DELIVERY OF NIMODIPINE." Journal of Pharma Research 7, no. 12 (2018): 305–13. https://doi.org/10.5281/zenodo.2616666.

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<strong><em>ABSTRACT</em></strong> &nbsp; <strong><em>T</em></strong><em>he objective of this study was to design and developed a rupturable coating type of pulsatile press coated tablet, which releases drug early in the morning hours. This delivery system was helpful to control an early morning surge in Blood Pressure because cardiovascular events occur more frequently in the morning. This delivery system would be useful for the prevention of cardiovascular events in hypertensive patients. Initially core tablet was prepared by using Nimodipine as a drug, and different concentration of cross c
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Sokar, M., A. Hanafy, A. Elkamel, and S. El-gamal. "Design of chronomodulated drug delivery system of valsartan: in vitro characterization." Indian Journal of Pharmaceutical Sciences 77, no. 4 (2015): 470. http://dx.doi.org/10.4103/0250-474x.164768.

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Chaudhary, SonaS, PunitB Parejiya, HetalK Patel, and PragnaK Shelat. "Chronomodulated drug delivery system of urapidil for the treatment of hypertension." International Journal of Pharmaceutical Investigation 5, no. 2 (2015): 107. http://dx.doi.org/10.4103/2230-973x.153389.

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Ali, J., J. Qureshi, Mohd Amir, Alka Ahuja, and Sanjula Baboota. "Chronomodulated drug delivery system of salbutamol sulphate for the treatment of nocturnal asthma." Indian Journal of Pharmaceutical Sciences 70, no. 3 (2008): 351. http://dx.doi.org/10.4103/0250-474x.43000.

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Dissertations / Theses on the topic "Chronomodulated drug delivery system"

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Berton, Damiano <1994&gt. "Microfluidic production of drug delivery system." Master's Degree Thesis, Università Ca' Foscari Venezia, 2021. http://hdl.handle.net/10579/19484.

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Leach, Jeffrey Harold. "Magnetic Targeted Drug Delivery." Thesis, Virginia Tech, 2003. http://hdl.handle.net/10919/31261.

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Methods of guiding magnetic particles in a controlled fashion through the arterial system in vivo using external magnetic fields are explored. Included are discussions of applications, magnetic field properties needed to allow guiding based on particle characteristics, hemodynamic forces, the uniformity of field and gradients, variable tissue characteristics, and imaging techniques employed to view these particles while in transport. These factors influence the type of magnetic guidance system that is needed for an effective drug delivery system. This thesis reviews past magnetic drug deliv
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Ho, Duc Hong Linh 1978. "Packaging for a drug delivery microelectromechanical system." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/30262.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2005.<br>Includes bibliographical references (p. 52-55).<br>Local drug delivery is a fast expanding field, and has been a center of attention for researchers in medicine in the last decade. Its advantages over systemic drug delivery are clear in cancer therapy, with localized tumors. A silicon microelectromechanical drug delivery device was fabricated for the purpose of delivering chemotherapeutic agents such-as carmustine, a potent brain cancer drug, directly to the site of the tumor. Limitations
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Dyer, Robert J. (Robert Joseph) 1977. "Needle-less injection system for drug delivery." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/89388.

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Bright, Anne M. "Towards an improved ocular drug delivery system." Thesis, Aston University, 1992. http://publications.aston.ac.uk/9801/.

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The ultimate aim of this project was to design new biomaterials which will improve the efficiency of ocular drug delivery systems. Initially, it was necessary to review the information available on the nature of the tear fluid and its relationship with the eye. An extensive survey of the relevant literature was made. There is a common belief in the literature that the ocular glycoprotein, mucin, plays an important role in tear film stability, and furthermore, that it exists as an adherent layer covering the corneal surface. If this belief is true, the muco-corneal interaction provides the idea
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Birudaraj, Kondamraj. "Transbuccal drug delivery: In vitro characterization of transport pathway of buspirone and bioadhesive drug delivery system." Scholarly Commons, 2001. https://scholarlycommons.pacific.edu/uop_etds/2733.

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The objective of this research was to investigate two important aspects of buccal drug delivery, transport and mucoadhesion. Buspirone was chosen as a model drug for the in vitro buccal transport studies, polyvinyl alcohol and sodium alginate polymer blends were prepared to investigate the mucoadhesive properties through a Lewis acid-base approach and finally, the effect of formulation factors on the force of mucoadhesion, surface energy parameters, release rate and flux was studied. In vitro permeation studies were conducted to investigate the buccal transport pathway of buspirone. Mathematic
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Warrilow, Philip A. D. "Polyamine conjugates as a potential drug delivery system." Thesis, University of Leicester, 1997. http://hdl.handle.net/2381/30012.

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The work in this thesis has covered three main topics; i) cytotoxic polyamine-conjugates ii) radiation protection polyamine-conjugates iii) polyamine conjugates which probe cellular uptake and DNA binding. The synthesis of these conjugates employed selective protection/deprotection steps, taking advantage of the BOC protecting groups regioselectivity of primary over secondary amines when reacting with naturally occurring polyamines. After promising in vitro and in vivo results of the original spermidine-chlorambucil synthesised by Wheelhouse (1990), attempts were made to improve this compound.
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Bosworth, Mark Erwin. "Evaluation of liposomes as a drug delivery system /." Ann Arbor : University Microfilms International, 1987. http://www.gbv.de/dms/bs/toc/016141032.pdf.

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Saeed, Aram Omer. "Toward advanced modular drug and gene delivery system." Thesis, University of Nottingham, 2010. http://eprints.nottingham.ac.uk/27632/.

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In chapter two, the development of new a nanoparticulate carrier system for gene delivery was described. The new nanocarrier consists of a blend matrix formed by a poly (lactic-eo-glycolic acid) (PLGA) and Poly(ethylene glycol) bis (3-aminopropyl) terminated (also known as JeffamineTM). Nanopartic1es were formulated based on a 50:50 weight ratio of PLGA:Jeffamine using a modified emulsification-solvent diffusion technique. The potential of these blended matrix nanoparticles for encapsulation efficiency of Calf Thymus DNA and release profile were also studied. The achieved encapsulation efficie
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Blackwell, Lisa Jane. "Sporopollenin exines as a novel drug delivery system." Thesis, University of Hull, 2007. http://hydra.hull.ac.uk/resources/hull:7162.

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Microcapsules are fast becoming the most successful delivery systems for the oral delivery of drugs and food additives. Since many drugs are proteins and are destroyed in acidic conditions, microcapsules offer protection against the harsh environment of the gastrointestinal (GI) tract. Although the use of microcapsules achieves controlled release of the inner material, many synthetically designed microcapsules lack consistency in their size and morphology. The outer coat (exine) of plant pollen grains and spores is composed of the material sporopollenin. Sporopollenin exines (25µm diameter) we
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Books on the topic "Chronomodulated drug delivery system"

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Jain, Kewal K., ed. Drug Delivery System. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0363-4.

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Shah, Nirmal, ed. Nanocarriers: Drug Delivery System. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-4497-6.

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Frost & Sullivan., ed. Programmed drug delivery system markets. Frost & Sullivan, 1988.

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P, Johnson, and Lloyd-Jones J. G. 1944-, eds. Drug delivery system: Fundamentals and techniques. VCH, 1988.

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Jain, Kewal K., ed. Drug Delivery to the Central Nervous System. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-529-3.

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F, Smolen Victor, and Ball LuAnn, eds. Bioavailability control by drug delivery system design. Wiley, 1985.

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Parfenyuk, E. V. Silica nanoparticles as drug delivery system for immunomodulator GMDP. ASME, 2012.

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David, Ganderton, Jones T. M. 1942-, Pharmaceutical Society of Great Britain., and King's College (University of London). Chelsea Dept. of Pharmacy., eds. Drug delivery to the respiratory tract. VCH, 1987.

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Gregory, Gregoriadis, McCormack Brenda, Poste George, North Atlantic Treaty Organization. Scientific Affairs Division., and NATO Advanced Study Institute on Targeting of Drugs: Advances in System Constructs (1993 : Ákra Soúnion, Greece), eds. Targeting of drugs 4: Advances in system constructs. Plenum Press, 1994.

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Geest, Ronald van der. PK/PD based drug delivery system design: Iontophoretic apomorphine delivery in patients with Parkinson's disease. University of Leiden], 1998.

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Book chapters on the topic "Chronomodulated drug delivery system"

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Makino, Kimiko. "Drug Delivery System." In Electrical Phenomena at Interfaces and Biointerfaces. John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118135440.ch40.

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Godin, Biana, Elka Touitou, Rajaram Krishnan, et al. "Drug Delivery System." In Encyclopedia of Nanotechnology. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-90-481-9751-4_100192.

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Yang, Qiuhong, and Laird Forrest. "Drug Delivery to the Lymphatic System." In Drug Delivery. John Wiley & Sons, Inc, 2016. http://dx.doi.org/10.1002/9781118833322.ch21.

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On, Ngoc H., Vinith Yathindranath, Zhizhi Sun, and Donald W. Miller. "Pathways for Drug Delivery to the Central Nervous System." In Drug Delivery. John Wiley & Sons, Inc, 2016. http://dx.doi.org/10.1002/9781118833322.ch16.

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Zhang, Yan, and Donald W. Miller. "Pathways for Drug Delivery to the Central Nervous System." In Drug Delivery. John Wiley & Sons, Inc., 2005. http://dx.doi.org/10.1002/0471475734.ch3.

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Choudhary, Princy, and Sangeeta Singh. "Targeted Drug Delivery." In Biotechnology in the Modern Medicinal System. Apple Academic Press, 2021. http://dx.doi.org/10.1201/9781003129783-2.

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Gujarathi, Nayan A., Akshada A. Bakliwal, Bhushan R. Rane, et al. "Pulmonary Drug Delivery System." In Topical and Transdermal Drug Delivery Systems. Apple Academic Press, 2022. http://dx.doi.org/10.1201/9781003284017-9.

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Pillai, Akhilraj, Dhanashree Bhande, and Vinal Pardhi. "Controlled Drug Delivery System." In Studies in Mechanobiology, Tissue Engineering and Biomaterials. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-6564-9_11.

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Jain, Surendra K., Aristide Laurel Mokale Kognou, Deepti Jain, Vinod Dhote, and Rajesh Singh Pawar. "Chemical Drug Delivery System." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_12.

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Kumar, Amit, Kashid Saurabh Machhindra, Keerti Jain, and Awesh K. Yadav. "Transdermal Drug Delivery System." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_5.

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Conference papers on the topic "Chronomodulated drug delivery system"

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M, Moorthi, Gugan B.M, Mohammed Suhail K.S, et al. "Microfluidic Analysis of Micro Needle for Drug Delivery." In 2024 Control Instrumentation System Conference (CISCON). IEEE, 2024. http://dx.doi.org/10.1109/ciscon62171.2024.10696860.

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Jaiswal, Shalini, Pooja Singh, Shalini Srivastav, Renu Chaudhary, and Atul Kumar. "Noval Technology of Nano-Robot for Promising Drug Delivery System." In 2024 7th International Conference on Contemporary Computing and Informatics (IC3I). IEEE, 2024. https://doi.org/10.1109/ic3i61595.2024.10829002.

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"Drug Delivery System." In 2004 2nd IEEE/EMBS International Summer School on Medical Devices and Biosensors. IEEE, 2004. http://dx.doi.org/10.1109/issmd.2004.1689583.

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Mali, Ravindra, and Javesh Patil. "Nanomaterials: An Improvised Drug Delivery System through the Gastroretentive Drug Delivery System." In IOCN 2023. MDPI, 2023. http://dx.doi.org/10.3390/materproc2023014063.

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Ashraf, Muhammad Waseem, Shahzadi Tayyaba, Asim Nisar, and Nitin Afzulpurkar. "MEMS based system for drug delivery." In 2010 International Conference on Emerging Technologies (ICET). IEEE, 2010. http://dx.doi.org/10.1109/icet.2010.5638375.

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Maloney, John M. "An Implantable Microfabricated Drug Delivery System." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43186.

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We report on the development of a fully implantable drug delivery system capable of delivering hundreds of individual doses. This product is intended for the controlled release of potent therapeutic compounds that might otherwise require frequent injections. Our system has the following capabilities: • Stable, hermetic storage of therapeutic drugs in solid, liquid, or gel form; • Individual storage of discrete doses for multiple-drug regimens; • Wireless communication with an external controller for device monitoring and therapy modification; • Choice of preprogrammed release or release on com
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Luo, Yangyang, and David K. Mills. "Chitosan-Halloysite Hydrogel Drug Delivery System." In 2016 32nd Southern Biomedical Engineering Conference (SBEC). IEEE, 2016. http://dx.doi.org/10.1109/sbec.2016.55.

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Moussi, Khalil, Abdullah Bukhamsin, and Jurgen Kosel. "Implantable 3D Printed Drug Delivery System." In 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII). IEEE, 2019. http://dx.doi.org/10.1109/transducers.2019.8808496.

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NASTI, IVANA, VERA LA FERRARA, GABRIELLA RAMETTA, and GIROLAMO DI FRANCIA. "SILICON BASED TRANSDERMAL DRUG DELIVERY SYSTEM." In Proceedings of the 12th Italian Conference. WORLD SCIENTIFIC, 2008. http://dx.doi.org/10.1142/9789812833594_0049.

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Miyano, T., T. Miyachi, T. Okanishi, et al. "Hydrolyticmicroneedles as Transdermal Drug Delivery System." In TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference. IEEE, 2007. http://dx.doi.org/10.1109/sensor.2007.4300141.

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Reports on the topic "Chronomodulated drug delivery system"

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McPhillips, D. M., M. W. Price, J. W. Gibson, and R. A. Casper. Development of an On-Demand, Generic, Drug-Delivery System. Defense Technical Information Center, 1985. http://dx.doi.org/10.21236/ada158550.

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Pflugfelder Ghanashyam S., Stephen C. Broadly Applicable Nanowafer Drug Delivery System for Treating Eye Injuries. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada613401.

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Dash, Alekha K. Novel in Situ Gel Drug Delivery System for Breast Cancer Treatment. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada474685.

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Silva, João, Matheus Warmeling, and Rogério Pagnoncelli. Platelet-rich fibrin as a drug delivery system: a scoping review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.8.0004.

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Sledge, George W. Nanoparticle: Monoclonal Antibody Conjugates: A Novel Drug Delivery System in Human Breast Cancer. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada420569.

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Sledge, George. Nanoparticle: Monoclonal Antibody Conjugates: A Novel Drug Delivery System in Human Breast Cancer. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada393348.

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Choi, Soojeong, Seoeun Oh, and Ildoo Chung. Synthesis and characterization of L-lysine polyurethane (LPU) nanoparticles for drug delivery system. Peeref, 2023. http://dx.doi.org/10.54985/peeref.2307p9824908.

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Choi, Soojeong, Seoeun Oh, and Ildoo Chung. Synthesis and characterization of L-threonine polyurethane (LTHU) nanoparticles for drug delivery system. Peeref, 2023. http://dx.doi.org/10.54985/peeref.2307p3992803.

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Chakraborty, Payel, and Tamilvanan Shunmugaperumal. Simvastatin repurposing towards endometriosis management: The use of self -nanoemulsifying drug delivery system. Peeref, 2023. http://dx.doi.org/10.54985/peeref.2304p6131285.

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Silva, João, Matheus Warmeling, and Rogerio Pagnoncelli. Platelet-rich fibrin as a drug delivery system: Systematic review of in vitro studies. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.8.0005.

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