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Dissertations / Theses on the topic 'Chronomodulated drug delivery system'

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Published: 4 June 2025
Last updated: 1 August 2025

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1

Berton, Damiano <1994&gt. "Microfluidic production of drug delivery system." Master's Degree Thesis, Università Ca' Foscari Venezia, 2021. http://hdl.handle.net/10579/19484.

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2

Leach, Jeffrey Harold. "Magnetic Targeted Drug Delivery." Thesis, Virginia Tech, 2003. http://hdl.handle.net/10919/31261.

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Methods of guiding magnetic particles in a controlled fashion through the arterial system in vivo using external magnetic fields are explored. Included are discussions of applications, magnetic field properties needed to allow guiding based on particle characteristics, hemodynamic forces, the uniformity of field and gradients, variable tissue characteristics, and imaging techniques employed to view these particles while in transport. These factors influence the type of magnetic guidance system that is needed for an effective drug delivery system. This thesis reviews past magnetic drug deliv
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3

Ho, Duc Hong Linh 1978. "Packaging for a drug delivery microelectromechanical system." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/30262.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2005.<br>Includes bibliographical references (p. 52-55).<br>Local drug delivery is a fast expanding field, and has been a center of attention for researchers in medicine in the last decade. Its advantages over systemic drug delivery are clear in cancer therapy, with localized tumors. A silicon microelectromechanical drug delivery device was fabricated for the purpose of delivering chemotherapeutic agents such-as carmustine, a potent brain cancer drug, directly to the site of the tumor. Limitations
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4

Dyer, Robert J. (Robert Joseph) 1977. "Needle-less injection system for drug delivery." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/89388.

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5

Bright, Anne M. "Towards an improved ocular drug delivery system." Thesis, Aston University, 1992. http://publications.aston.ac.uk/9801/.

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The ultimate aim of this project was to design new biomaterials which will improve the efficiency of ocular drug delivery systems. Initially, it was necessary to review the information available on the nature of the tear fluid and its relationship with the eye. An extensive survey of the relevant literature was made. There is a common belief in the literature that the ocular glycoprotein, mucin, plays an important role in tear film stability, and furthermore, that it exists as an adherent layer covering the corneal surface. If this belief is true, the muco-corneal interaction provides the idea
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6

Birudaraj, Kondamraj. "Transbuccal drug delivery: In vitro characterization of transport pathway of buspirone and bioadhesive drug delivery system." Scholarly Commons, 2001. https://scholarlycommons.pacific.edu/uop_etds/2733.

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The objective of this research was to investigate two important aspects of buccal drug delivery, transport and mucoadhesion. Buspirone was chosen as a model drug for the in vitro buccal transport studies, polyvinyl alcohol and sodium alginate polymer blends were prepared to investigate the mucoadhesive properties through a Lewis acid-base approach and finally, the effect of formulation factors on the force of mucoadhesion, surface energy parameters, release rate and flux was studied. In vitro permeation studies were conducted to investigate the buccal transport pathway of buspirone. Mathematic
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7

Warrilow, Philip A. D. "Polyamine conjugates as a potential drug delivery system." Thesis, University of Leicester, 1997. http://hdl.handle.net/2381/30012.

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The work in this thesis has covered three main topics; i) cytotoxic polyamine-conjugates ii) radiation protection polyamine-conjugates iii) polyamine conjugates which probe cellular uptake and DNA binding. The synthesis of these conjugates employed selective protection/deprotection steps, taking advantage of the BOC protecting groups regioselectivity of primary over secondary amines when reacting with naturally occurring polyamines. After promising in vitro and in vivo results of the original spermidine-chlorambucil synthesised by Wheelhouse (1990), attempts were made to improve this compound.
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8

Bosworth, Mark Erwin. "Evaluation of liposomes as a drug delivery system /." Ann Arbor : University Microfilms International, 1987. http://www.gbv.de/dms/bs/toc/016141032.pdf.

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9

Saeed, Aram Omer. "Toward advanced modular drug and gene delivery system." Thesis, University of Nottingham, 2010. http://eprints.nottingham.ac.uk/27632/.

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In chapter two, the development of new a nanoparticulate carrier system for gene delivery was described. The new nanocarrier consists of a blend matrix formed by a poly (lactic-eo-glycolic acid) (PLGA) and Poly(ethylene glycol) bis (3-aminopropyl) terminated (also known as JeffamineTM). Nanopartic1es were formulated based on a 50:50 weight ratio of PLGA:Jeffamine using a modified emulsification-solvent diffusion technique. The potential of these blended matrix nanoparticles for encapsulation efficiency of Calf Thymus DNA and release profile were also studied. The achieved encapsulation efficie
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10

Blackwell, Lisa Jane. "Sporopollenin exines as a novel drug delivery system." Thesis, University of Hull, 2007. http://hydra.hull.ac.uk/resources/hull:7162.

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Microcapsules are fast becoming the most successful delivery systems for the oral delivery of drugs and food additives. Since many drugs are proteins and are destroyed in acidic conditions, microcapsules offer protection against the harsh environment of the gastrointestinal (GI) tract. Although the use of microcapsules achieves controlled release of the inner material, many synthetically designed microcapsules lack consistency in their size and morphology. The outer coat (exine) of plant pollen grains and spores is composed of the material sporopollenin. Sporopollenin exines (25µm diameter) we
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11

Lee, Yan Sim. "The development of controlled-chemotherapy drug delivery system." Thesis, University of Bath, 2009. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512304.

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The aim of this thesis was to develop biodegradable devices loaded with chemotherapy drug. The system is targeted for advanced ovarian cancer treatment through the intraperitoneal (IP) route of administration. Polylactide-co-glycolide (PLGA) was selected as the model biodegradable polymer to produce drug-loaded microsphere, hollow and solid fibres. Copolymer PLGA with three different lactic:glycolic acids ratios; 50:50, 65:35 and 75:25 were used in order to compare their drug loading capacities and in vitro drug release profiles. Cisplatin, a cytotoxic drug with proven activity against ovarian
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12

Salvage, Jonathan Peter. "A novel phosphorylcholine-based nanoparticulate drug delivery system." Thesis, University of Brighton, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499068.

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Phosphorylcholine (PC) based materials have been shown to have increased biocompatibility when compared to more established bio-implantable materials. This has been attributed to the ability of PC to mimic the cell lipid bilayer membrane, resulting in reduced protein adhesion and cellular interaction / activation. PC research has previously focused on the areas of contact lens formulation and medical device coating. This project sought to harness the biomimetic properties of PC to develop novel systems for drug delivery, with the emphasis being focused on microparticulate drug delivery.
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13

MODICA, DE MOHAC Laura. "Novel Drug Delivery System for Treatment-Resistant Schizophrenia." Doctoral thesis, Università degli Studi di Palermo, 2021. http://hdl.handle.net/10447/478483.

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14

Nguyen, Thi Lam Uyen Nguyen Centre for Advanced Macromolecular Design Faculty of Engineering UNSW. "Crosslinked microspheres as drug delivery system for liver cancer." Publisher:University of New South Wales. Centre for Advanced Macromolecular Design, 2008. http://handle.unsw.edu.au/1959.4/41528.

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It has been demonstrated that 1,25 dihydroxy vitamin D3 (1,25 (OH)2VD3) can inhibit the proliferation of cancer cells including colorectal and hepatocellular cells which are mainly responsible for liver cancer. However, the use of 1, 25 (OH)2VD3 is hampered due to the development of hypercalcaemia. Current treatment using hepatic arterial delivery of drug solution is inconvenient since repetitive invasive treatments are required. This work aims to tackle this problem by utilizing crosslinked microspheres prepared by suspension polymerization as a carrier to control the release of 1, 25 (OH)2VD
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15

Roxhed, Niclas. "A Fully Integrated Microneedle-based Transdermal Drug Delivery System." Doctoral thesis, Stockholm : Kungliga Tekniska högskolan, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4484.

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16

Freddi, Matthew James. "Intra-articular depot forming drug delivery system for osteoarthritis." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/12662/.

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Osteoarthritis (OA) is a chronic degenerative disease of the joint. Current treatments for this disease (such as glucocorticoid steroids) aim to reduce pain and increase mobility. Intra-articular injection is used in OA as treatment can be targeted to affected joints only. There is currently a lack of sustained release formulations for intra-articular injection. The aim of this thesis was to produce and characterise an injectable intra-articular drug delivery system capable of providing delivery of the steroid dexamethasone phosphate (DXMP) over 3 months. This would be an injectable hydrogel t
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17

Goettsche, Thorsten [Verfasser], Roland [Akademischer Betreuer] Zengerle, and Gerald A. [Akademischer Betreuer] Urban. "IntelliDrug - controlled, oral drug delivery system as tooth implant." Freiburg : Universität, 2016. http://d-nb.info/1128574195/34.

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18

Taimur, Muhammad <1992&gt. "Drug delivery system for the treatment of burn injuries." Master's Degree Thesis, Università Ca' Foscari Venezia, 2020. http://hdl.handle.net/10579/17961.

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With the advancements in medicine, various solutions have been proposed to treat skin burns. But serious burns interesting a large area of body surface remain a major cause of subsequent infections because of several factors, such as poor penetration of drugs through skin barrier, availability of bacterial nutrients in the burned area, destruction of the vascular supply to the burned skin. All these factors jointly make burns vulnerable to infection. To overcome these factors and other limitations of conventional burn injury treatments, we have proposed a formulation. In the present study, we
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19

Babu, Kavitha Mary Vadakkel. "The Development of a Novel Controlled Release Drug Delivery System." The University of Waikato, 2007. http://hdl.handle.net/10289/2590.

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The aim of this research was to formulate, characterise and assess the feasibility of a novel drug delivery system known as the in situ gelling matrix (ISGM) where a hydrophilic polymer is suspended in a non-aqueous solvent that converts into a gel when injected subcutaneously or intramuscularly thus giving a controlled release matrix for a drug. Although the concept has been patented with claims that this kind of drug delivery is achievable in theory for a wide variety of candidate substances, actual formulation studies for making a commercially viable product for this technology are complet
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20

Hemond, Brian D. (Brian David Thomson). "A Lorentz-force actuated controllable needle-free drug delivery system." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/37201.

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Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, June 2004; and, (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, February 2006.<br>Includes bibliographical references (leaves 89-90).<br>The advantages of delivering injections via needle-free methods are numerous. However, conventional methods for needle-free injection lack sufficient control over depth of penetration and shape of injection. Thus, a needle-free injector was designed, constructed, and tested, using a controllable li
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21

Venugopal, Balaji. "Preclinical evaluation of a novel drug delivery system for cisplatin." Thesis, University of Glasgow, 2012. http://theses.gla.ac.uk/4198/.

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The aim of this body of work was to characterise a novel cisplatin drug delivery system and to develop new tools based on biophotonic imaging that could be used to enhance studies of drug delivery in vivo. Cucurbiturils (CB) are macrocycles which are formed by acid catalysed condensation of glycoluril and formaldehyde. The internal cavity of CB[7] encapsulates a single molecule of cisplatin and the hypothesis was that encapsulation would reduce thiol degradation of the drug. Drug sensitivity studies in vitro with the cisplatin-sensitive human ovarian cancer cell line, A2780, and a cisplatin-re
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22

Gilbert, Helena Rosalind Petra. "Bioresponsive polymer-protection conjugates as a unimolecular drug delivery system." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/55685/.

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PEGylation has become very popular for the generation of nanomedicines with improved protein delivery properties, despite its lack of biodegradability. Researchers usually try to maximise retained protein activity during PEGylation. However, this proof of principle study aimed to create an inactive peptide or enzyme product, using a biodegradable polymer, that would elicit minimal activity/non-specific toxicity on administration. Following triggered site-specific degradation of the polymer, the hypothesis was that protein activity could be slowly regenerated in the general circulation or local
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23

Abdulrazzaq, Fadi. "Aquasomes as a drug delivery system for proteins and peptides." Thesis, Aston University, 2016. http://publications.aston.ac.uk/30080/.

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Aquasomes are nanocarrier systems consist of three distinctive layers; an inner core, a polyhydroxy carbohydrate layer and an outer layer of an API (Kossovsky et al., 1991). Aquasomes have a unique structure and ability to carry active molecules through a non-covalent bounding and provide superior stability, especially for proteins and peptides (Masatoshi and Yongning, 1998; Kim and Kim, 2002; Khopade et al., 2002). Different core and coating materials were used to prepare aquasomes under different conditions to investigate the relationship between preparation conditions and loading efficiency
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24

Rodriguez, Lidia Betsabe. "Controlled Release System for Localized and Sustained Drug Delivery Applications." University of Toledo / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1365107103.

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25

Beier, Anne Mette. "Chitosan microparticles as a drug delivery system for protein vaccines /." [Cph.] : Pharmexa A/S : Department of Pharmaceutics, The Royal Danish School of Pharmacy, 2002. http://www.dfh.dk/phd/defences/annemettebeier.htm.

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26

BRUNO, GIACOMO. "Leveraging nanochannels for a remotely controllable implantable drug delivery system." Doctoral thesis, Politecnico di Torino, 2017. http://hdl.handle.net/11583/2676478.

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This work is focused on the research on how to leverage nanochannels in the eld of Nanomedicine. More speci cally the study of different diffusion regimes at the nanoscale thanks to the close collaboration between the Politecnico di Torino, Turin, Italy, and the Methodist Hospital Research Institute, Houston, Texas. The therapeutics ow through nanochannels can be tightly controlled by several factors such as channels dimension, channel polarity, solution ionic strength just to name a few. The major advantage of this nanotechnology is that the drug ow results to be linear over time and pract
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27

Cecchin, Denis. "Study and characterization of drug delivery system in regenerative medicine." Doctoral thesis, Università degli studi di Padova, 2010. http://hdl.handle.net/11577/3422729.

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Abstract Drug delivery system (DDS) technology is particularly promising to improve the in vivo efficiency of active molecules. Moreover, it is possible to stabilize and prolong the half life at biologically active molecules, thus prolonging the in vitro activity. DDS's can be used either for the delivery of anticancer drug but also for the controlled release of growth factors essential for the tissue engineering. In this work DDS’s have been investigate to develop new targeted anticancer drug or to control the release of growth factor for tissue engineering. In the first case polymer conju
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28

Shojaei, Amir Hossein. "Buccal mucoadhesive delivery system of acyclovir." Scholarly Commons, 1997. https://scholarlycommons.pacific.edu/uop_etds/2626.

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Novel buccal mucoadhesive copolymers of acrylic acid (AA) and poly (ethylene glycol) monomethylether monomethacrylate (PEGMM), (P(AA-co-PEG)), were designed, synthesized, and characterized for systemic delivery of acyclovir across the buccal mucosa. To achieve spontaneous intimate contact between polymer and buccal mucosa, the surface properties of P(AA-co-PEG) were optimized for buccal adhesion by varying the composition of the copolymers. It was found that the mole ratio of the repeat units of PEG, ethylene glycol, to AA is of great importance for mucoadhesion. ATR-FTIR studies revealed that
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29

Yang, Xiaojuan. "Development of Nanoparticle Systems for Therapeutic Drug Delivery." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1248972068.

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30

Falahat, Rana. "Tunable Nano-Delivery System for Cancer Treatment: A New Approach for Targeted Localized Drug Delivery." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6234.

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Localized drug delivery systems have been widely studied as potential replacements for conventional chemotherapy with the capability of providing sustained and controlled drug release in specific targeted sites. They offer numerous benefits over conventional chemotherapy such as enhancing the stability of embedded drugs and preserving their anticancer activity, providing sustained and controlled drug release in the tumor site, reducing toxicity and diminishing subsequent side effects, minimizing the drug loss, averting the need for frequent administrations, and minimizing the cost of therapy.
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31

Chinnakavanam, Sundararaj Sharath Kumar. "Development of a Multilayered Association Polymer System for Sequential Drug Delivery." UKnowledge, 2013. http://uknowledge.uky.edu/cbme_etds/13.

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As all the physiological processes in our body are controlled by multiple biomolecules, comprehensive treatment of certain disease conditions may be more effectively achieved by administration of more than one type of drug. Thus, the primary objective of this research was to develop a multilayered, polymer-based system for sequential delivery of multiple drugs. This particular device was designed aimed at the treatment of periodontitis, a highly prevalent oral inflammatory disease that affects 90% of the world population. This condition is caused by bacterial biofilm on the teeth, resulting in
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32

Wong, Ling Wai. "Molecular delivery system based on the nanoporous zeolite microstructures /." View abstract or full-text, 2006. http://library.ust.hk/cgi/db/thesis.pl?BIEN%202006%20WONG.

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33

Lee, Wang Wang. "Factors affecting drug release and absorption from a novel oral delayed release drug delivery system." Thesis, Durham University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269886.

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34

Venthoye, M. Geraldine. "Characterisation of an amorphous dry powder aerosol system." Thesis, University College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265519.

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35

Hawley, Ann Elizabeth. "The uptake of nanospheres by the lymphatic system." Thesis, University of Nottingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307765.

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36

Zeng, Jianming. "Constrained crystallization and depletion in the polymer medium for transdermal drug delivery system." Diss., Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/5102.

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Transdermal drug delivery systems (TDS) are pharmaceutical devices that are designed to deliver specific drugs to the human body by diffusion through skin. The TDS effectiveness suffers from crystallization in the patch when they are kept in storage for more than two years. It has been reported that there are two types of crystals in the patch: needle and aggregate, and growth of drug crystals in TDS generally occurs only in the middle third of the polymer layer. In our study, fluorescence microscopy, EDS (SEM) and Raman microspectroscopy were used to further characterize the crystals. The res
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37

Svirskis, Darren. "Development of a novel drug delivery system based on conducting polymers." Thesis, University of Auckland, 2010. http://hdl.handle.net/2292/6568.

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Controlled release systems offer advantages over conventional therapies by maintaining drug concentrations at therapeutically desired levels whilst simultaneously improving compliance. Intrinsically Conducting Polymers (ICP) are organic materials that have electrical, magnetic and optical properties usually associated with metals, whilst retaining the advantageous mechanical properties and ease of processing usually associated with polymers. A novel drug delivery system, based on the ICP polypyrrole (PPy), has been developed to provide for the controlled release of risperidone. Due to t
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Cheng, Erik Ho Yan. "Combination of hydrogel and liposomes as a responsive drug delivery system." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ29374.pdf.

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39

NASCIMENTO, Débora Dolores Souza da Silva. "Obtenção de drug delivery system carbamazepina-zif-8 visando liberação prolongada." Universidade Federal de Pernambuco, 2017. https://repositorio.ufpe.br/handle/123456789/25939.

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Submitted by Fernanda Rodrigues de Lima (fernanda.rlima@ufpe.br) on 2018-08-20T20:30:39Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Débora Dolores Nascimento.pdf: 3594688 bytes, checksum: cdf7df39006953035bd1e74095fb8d37 (MD5)<br>Approved for entry into archive by Alice Araujo (alice.caraujo@ufpe.br) on 2018-08-28T18:14:14Z (GMT) No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Débora Dolores Nascimento.pdf: 3594688 bytes, checksum: cdf7df39006953035bd1e74095fb8d37 (MD5)<br>M
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Al, Thaher Yazan. "Antimicrobial drug LbL-assembled delivery system for orthopaedic nanocomposite bone cements." Thesis, Cardiff University, 2018. http://orca.cf.ac.uk/112718/.

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Total joint replacement (TJR) is commonly used for the treatment of end stage arthritis. The use of Poly-methylmethacrylate (PMMA) bone cement is a gold standard TJR, where it is frequently used for local delivery of antibiotics to provide prophylaxis from prosthetic joint infections (PJI). Currently used antibiotic loaded bone cements have many limitations, including burst release which fall below inhibitory levels leading to the selection of antibiotic resistant strains. This study aims to provide a controlled release for antimicrobial agents from bone cement to provide prophylaxis from post
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Gaspar, Diana Patrícia Rodrigues. "Novel strategy to produce a drug delivery system for skin regeneration." Master's thesis, Universidade da Beira Interior, 2012. http://hdl.handle.net/10400.6/1118.

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Skin lesions are traumatic events that lead to the increase of fluid loss, infections, scarring and locally immunocompromised regions. These injuries can be caused by genetic disorders, acute trauma or even surgical interventions. In these situations, a substantial area of skin can be damaged, often without the possibility of being regenerated. Scientists have put a lot of effort in the development of suitable drug delivery systems suitable to release therapeutic molecules that are required for the initials phases of the wound healing process. Cell microencapsulation arises as an alternative a
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Riaz, Muhammad Kashif. "Peptide functionalized drug delivery system for an efficient lung cancer therapy." HKBU Institutional Repository, 2019. https://repository.hkbu.edu.hk/etd_oa/609.

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Lung cancer has a high incidence rate globally and the leading cause of cancer related mortalities. In 2018, lung cancer has been estimated to cause 1.76 million deaths worldwide (18.33% of total cancer mortalities). In Hong Kong lung cancer has been a leading cause of cancer related deaths, and in 2016 caused 3780 deaths (26.6% of total cancer mortalities). Non-small cell lung cancer (NSCLC) is the major (~85%) lung cancer type, and five-year survival rate for lung cancer has estimated to be 18%. Thus, an efficient lung cancer treatment with lesser adverse effects is need of the hour. In this
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43

Holmberg, Alexander. "Developing an implantable drug delivery system for ecological studies on fish." Thesis, Umeå universitet, Institutionen för integrativ medicinsk biologi (IMB), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-169961.

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44

Kuo, Chan-Hsuan, and 郭蟬瑄. "Estimation the transdermal drug delivery efficiency of the handheld liquid drug delivery system." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/kfnx33.

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碩士<br>國立臺灣科技大學<br>醫學工程研究所<br>106<br>Drug permeation through the skin is usually limited by the stratum corneum in epidermis. In this study, the efficacy of a hand-held liquid drug delivery system for transdermal drug delivery will be evaluated. GNT GoldMedTM handheld liquid drug delivery system is a needle-free and low pressure of gas-powered injection system which can be used for transdermal biomaterials or drugs delivery. This study is mainly to assess the gas pressure, gas inflation time, flux and penetration depth of transdermal drug delivery by using this hand-held liquid drug delivery sy
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45

Zhang, Mengjue. "Microfluidic system development for drug delivery." Thesis, 2016. http://hdl.handle.net/2440/102614.

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Development and application of a microfluidic system for generating drug delivery carriers are investigated in this research. Various types of microfluidic devices are designed and fabricated for peptide nanotubes, liposome vesicles and double emulsions formation. The microfluidic system offers a better control over the formation process of all three drug delivery carriers. Comparing to traditional methods such as bulk mixing, the process efficiency, size and size distribution of the final products are significantly improved. The results generated show that tuning the flow rate ratios between
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Sarkar, Ruma Prodhan. "Liposomes as a selective ocular drug delivery system /." 1990. http://www.gbv.de/dms/bs/toc/128356219.pdf.

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47

丘宏治. "Study on in vitro iontophoretic drug delivery system." Thesis, 1991. http://ndltd.ncl.edu.tw/handle/73461551618461178561.

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48

Feng, Shieh Meng, and 謝孟峰. "Using Liposome encapsulated Taxol as drug delivery system." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/50097590751869602574.

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49

HE, XIU-E., and 何秀娥. "The study of fibrin based drug delivery system." Thesis, 1992. http://ndltd.ncl.edu.tw/handle/47743552199932124911.

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50

Du, Toit Lisa Claire. "Formulation of an anti-tuberculosis drug delivery system." Thesis, 2008. http://hdl.handle.net/10539/4805.

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ABSTRACT:Tuberculosis (TB) is a leading killer of young adults worldwide and the global scourge of multi-drug resistant tuberculosis is reaching epidemic proportions. A number of novel drug delivery systems incorporating the principle anti-tuberculosis (anti-TB) agents have been fabricated that either target the site of TB infection or reduce the dosing frequency with the aim of improving patient outcomes; however, there is a requisite to manufacture an oral system, which directly addresses issues of unacceptable rifampicin (RIF) bioavailability recently reported in a number of fixed-dose
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