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Relevant bibliographies by topics / Chrozophora senegalensis

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Journal articles

Academic literature on the topic 'Chrozophora senegalensis'

Author: Grafiati

Published: 4 June 2025

Last updated: 23 June 2025

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Journal articles on the topic "Chrozophora senegalensis"

1

Kwaji, Andrew, Saminu Yunana, Samaila Abubakar, and Atiko Rejoice. "Chrozophora senegalensis A. Juss brine shrimp activity." Journal of Pharmacognosy and Phytochemistry 12, no. 5 (2023): 132–34. http://dx.doi.org/10.22271/phyto.2023.v12.i5b.14721.

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2

Usman, H., Y. M. Musa, AA Ahmadu, and MA Tijjani. "Phytochemical And Antimicrobial Effects Of Chrozophora senegalensis." African Journal of Traditional, Complementary and Alternative Medicines 4, no. 4 (2008): 488. http://dx.doi.org/10.4314/ajtcam.v4i4.31242.

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3

Andrew, Kwaji, Saminu Yunana, Abubakar Samaila, Atiko Rejoice, and Aliyu U. Elnafaty. "Screening for Potential Antioxidants from <i>Chrozophora senegalensis</i> Crude Extract." Dutse Journal of Pure and Applied Sciences 10, no. 1c (2024): 118–29. http://dx.doi.org/10.4314/dujopas.v10i1c.11.

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Numerous reports have indicated oxidative stress as the under-laying factor or associated with the onset or progression of numerous human ailments and disorders such as dementia, Alzheimer disease, diabetes, macular degeneration and aging. Chrozophora senegalensis (C. senegalensis) is a plant used in traditional medicine to cure both infectious and non-infectious diseases. This research was aimed to carry out the antioxidant activities guided isolation and characterization of phytocompounds from C. senegalensis methanol crude extract. The plant sample was extracted using maceration and concentrated on a rotary evaporator at 45oC. Three different but complementary methods; Ferric reducing antioxidant power (FRAP), Nitric oxide and hydrogen peroxide assays were used to evaluate the antioxidant activities of C. senegalensis crude extracts. Column chromatography was used to isolate and purify the compounds from the most active n-hexane fraction and coded as CSC-1, CSC-2 and CSC-3. The compounds were characterized using NMR (1H & 13C), GC-MS, melting point determination and in comparison with literature. The percentage free radical scavenging activity for FRAP, nitric oxide and hydrogen peroxide assays were 94.51%, 92.38% and 91.67% respectively while that of ascorbic acid standard was 95.43±0.76%. The isolated compounds were identified as 1- hexacosanol (CSC-1), 1-triacontanol (CSC-2) and oleic acid (CSC-3). The isolation and characterization of these bioactive compounds from C. senegalensis crude extract validates its usefulness in traditional medicine practice.

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4

Vassallo, Antonio, Giuseppina Cioffi, Francesco De Simone, et al. "New Flavonoid Glycosides from Chrozophora senegalensis and Their Antioxidant Activity." Natural Product Communications 1, no. 12 (2006): 1934578X0600101. http://dx.doi.org/10.1177/1934578x0600101204.

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Bioassay-directed fractionation of an antioxidant methanol extract of the leaves of Chrozophora senegalensis using DPPH assay led to the isolation of three new flavonoid glycosides, quercetin 3-O-(6″-caffeoyl)-β-D-glucopyranoside-3′-O-β-D-glucopyranoside (1), quercetin 3-methyl ether-7-O-α-L-rhamnopyranosyl-(1→6)-(2″-p-coumaroyl)-β-D-glucopyranoside (2), acacetin 7-O-(6″-p-coumaroyl)-β-D-glucopyranoside (3), along with five known flavonoids, one phenolic derivative, and three megastigmane glycosides. Their structures were established on the basis of detailed spectral analysis. All isolated compounds were tested for their antioxidant activity on DPPH stable radical, superoxide anion, metal chelating activity, and DNA cleavage induced by the photolysis of H2O2. Quercetin 3-O-(6″-caffeoyl)-β-D-glucopyranoside-3′-O-β-D-glucopyranoside (1), quercetin 3′-methyl ether-3-O-α-L-rhamnopyranoside (4), and 4″'-methyl ether amenthoflavone (9) exhibited the highest antioxidant capacity being also able to modulate hydroxyl radical formation more efficiently than other compounds acting as direct hydroxyl radical scavengers and chelating iron.

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5

Makun, B., and A. A. Ebbo. "In vitro studies of antibacterial properties of aqueous leaf extract of chrozophora senegalensis on sheep diarrhea." Direct Research Journal of Biology and Biotechnology 4, no. 5 (2019): 86–90. https://doi.org/10.5281/zenodo.3375026.

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Antibacterial studies of aqueous leaf extract of<em> Chrozophora senegalensis </em>was conducted on bacterial isolate from sheep diarrhea using 100, 200, 300, 400 and 500 mg/mL of the extract and neomycin at 10µg/mL as control. The isolates obtained were Salmonella, Shigella and Klebsiella spp. There was a dose dependent increase in sensitivity of all isolates to the extract, with the highest concentration being comparable to the neomycin at 10µg/mL.  It was therefore concluded that the extract can be used as a remedy against bacterial diarrhea.

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6

Benoit-Vical, F., P. Njomnang Soh, M. Saléry, L. Harguem, C. Poupat, and R. Nongonierma. "Evaluation of Senegalese plants used in malaria treatment: Focus on Chrozophora senegalensis." Journal of Ethnopharmacology 116, no. 1 (2008): 43–48. http://dx.doi.org/10.1016/j.jep.2007.10.033.

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7

Garcia-Alvarez, M. C., I. Moussa, P. Njomnang Soh, et al. "Both plants Sebastiania chamaelea from Niger and Chrozophora senegalensis from Senegal used in African traditional medicine in malaria treatment share a same active principle." Journal of Ethnopharmacology 149, no. 3 (2013): 676–84. http://dx.doi.org/10.1016/j.jep.2013.07.024.

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8

Tarallo, Valeria, Laura Lepore, Marcella Marcellini, et al. "The Biflavonoid Amentoflavone Inhibits Neovascularization Preventing the Activity of Proangiogenic Vascular Endothelial Growth Factors." Journal of Biological Chemistry 286, no. 22 (2011): 19641–51. http://dx.doi.org/10.1074/jbc.m110.186239.

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The proangiogenic members of VEGF family and related receptors play a central role in the modulation of pathological angiogenesis. Recent insights indicate that, due to the strict biochemical and functional relationship between VEGFs and related receptors, the development of a new generation of agents able to target contemporarily more than one member of VEGFs might amplify the antiangiogenic response representing an advantage in term of therapeutic outcome. To identify molecules that are able to prevent the interaction of VEGFs with related receptors, we have screened small molecule collections consisting of >100 plant extracts. Here, we report the isolation and identification from an extract of the Malian plant Chrozophora senegalensis of the biflavonoid amentoflavone as an antiangiogenic bioactive molecule. Amentoflavone can to bind VEGFs preventing the interaction and phosphorylation of VEGF receptor 1 and 2 (VEGFR-1,VEGFR-2) and to inhibit endothelial cell migration and capillary-like tube formation induced by VEGF-A or placental growth factor 1 (PlGF-1) at low μm concentration. In vivo, amentoflavone is able to inhibit VEGF-A-induced chorioallantoic membrane neovascularization as well as tumor growth and associated neovascularization, as assessed in orthotropic melanoma and xenograft colon carcinoma models. In addition structural studies performed on the amentoflavone·PlGF-1 complex have provided evidence that this biflavonoid effectively interacts with the growth factor area crucial for VEGFR-1 receptor recognition. In conclusion, our results demonstrate that amentoflavone represents an interesting new antiangiogenic molecule that is able to prevent the activity of proangiogenic VEGF family members and that the biflavonoid structure is a new chemical scaffold to develop powerful new antiangiogenic molecules.

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9

AA, Ebbo, Bello A, and Liman YM. "Anti-Diarrheal Studies of Aqueous Leaf Extract of Chrozophora Senegalensis in Albino Rats." Archives of Clinical and Medical Case Reports 03, no. 04 (2019). http://dx.doi.org/10.26502/acmcr.96550070.

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10

AA, Ebbo. ""Anti-Diarrheal Studies of Aqueous Leaf Extract of Chrozophora Senegalensis in Albino Rats"." Journal of pharmacology & clinical research 7, no. 4 (2019). http://dx.doi.org/10.19080/jpcr.2019.07.555716.

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