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Relevant bibliographies by topics / Cilia/physiology

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Academic literature on the topic 'Cilia/physiology'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Cilia/physiology"

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Cajanek, Lukas. "A play on cilia beating." Journal of Biological Chemistry 295, no. 42 (2020): 14260–61. http://dx.doi.org/10.1074/jbc.h120.015887.

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Motile cilia, hairlike structures present on the cell surface, have a well-appreciated role in human physiology, including sweeping mucus, dirt and debris out of the respiratory tract. However, we are only beginning to understand the mechanisms governing cilia growth, maintenance and function. In this issue, Arora et al. reveal new details about the control of cilia growth. They identify a previously unrecognized connection between adenylate cyclase 6 (AC6), a cilia signaling mediator, and the autophagy-mediated regulation of motile cilia length via kinesin Kif19a, a regulator of cilia length.

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Pellicciotta, Nicola, Evelyn Hamilton, Jurij Kotar, et al. "Entrainment of mammalian motile cilia in the brain with hydrodynamic forces." Proceedings of the National Academy of Sciences 117, no. 15 (2020): 8315–25. http://dx.doi.org/10.1073/pnas.1910065117.

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Motile cilia are widespread across the animal and plant kingdoms, displaying complex collective dynamics central to their physiology. Their coordination mechanism is not generally understood, with previous work mainly focusing on algae and protists. We study here the entrainment of cilia beat in multiciliated cells from brain ventricles. The response to controlled oscillatory external flows shows that flows at a similar frequency to the actively beating cilia can entrain cilia oscillations. We find that the hydrodynamic forces required for this entrainment strongly depend on the number of cili

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Satir, P., and M. A. Sleigh. "The Physiology of Cilia and Mucociliary Interactions." Annual Review of Physiology 52, no. 1 (1990): 137–55. http://dx.doi.org/10.1146/annurev.ph.52.030190.001033.

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Ringers, Christa, Emilie W. Olstad, and Nathalie Jurisch-Yaksi. "The role of motile cilia in the development and physiology of the nervous system." Philosophical Transactions of the Royal Society B: Biological Sciences 375, no. 1792 (2019): 20190156. http://dx.doi.org/10.1098/rstb.2019.0156.

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Motile cilia are miniature, whip-like organelles whose beating generates a directional fluid flow. The flow generated by ciliated epithelia is a subject of great interest, as defective ciliary motility results in severe human diseases called motile ciliopathies. Despite the abundance of motile cilia in diverse organs including the nervous system, their role in organ development and homeostasis remains poorly understood. Recently, much progress has been made regarding the identity of motile ciliated cells and the role of motile-cilia-mediated flow in the development and physiology of the nervou

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McClintock, Timothy S., Chad E. Glasser, Soma C. Bose, and Daniel A. Bergman. "Tissue expression patterns identify mouse cilia genes." Physiological Genomics 32, no. 2 (2008): 198–206. http://dx.doi.org/10.1152/physiolgenomics.00128.2007.

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In mammals, cilia are critical for development, sensation, cell signaling, sperm motility, and fluid movement. Defects in cilia are causes of several congenital syndromes, providing additional reasons to identify cilia-related genes. We hypothesized that mRNAs selectively abundant in tissues rich in highly ciliated cells encode cilia proteins. Selective abundance in olfactory epithelium, testes, vomeronasal organ, trachea, and lung proved to be an expression pattern uniquely effective in identifying documented cilia-related genes. Known and suspected cilia-related genes were statistically over

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Chen, Siwei, Wedad Alhassen, Roudabeh Vakil Monfared, et al. "Dynamic Changes of Brain Cilia Transcriptomes across the Human Lifespan." International Journal of Molecular Sciences 22, no. 19 (2021): 10387. http://dx.doi.org/10.3390/ijms221910387.

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Almost all brain cells contain primary cilia, antennae-like microtubule sensory organelles, on their surface, which play critical roles in brain functions. During neurodevelopmental stages, cilia are essential for brain formation and maturation. In the adult brain, cilia play vital roles as signaling hubs that receive and transduce various signals and regulate cell-to-cell communications. These distinct roles suggest that cilia functions, and probably structures, change throughout the human lifespan. To further understand the age-dependent changes in cilia roles, we identified and analyzed age

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Soulavie, Fabien, David Piepenbrock, Joëlle Thomas, et al. "hemingway is required for sperm flagella assembly and ciliary motility in Drosophila." Molecular Biology of the Cell 25, no. 8 (2014): 1276–86. http://dx.doi.org/10.1091/mbc.e13-10-0616.

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Cilia play major functions in physiology and development, and ciliary dysfunctions are responsible for several diseases in humans called ciliopathies. Cilia motility is required for cell and fluid propulsion in organisms. In humans, cilia motility deficiencies lead to primary ciliary dyskinesia, with upper-airways recurrent infections, left–right asymmetry perturbations, and fertility defects. In Drosophila, we identified hemingway (hmw) as a novel component required for motile cilia function. hmw encodes a 604–amino acid protein characterized by a highly conserved coiled-coil domain also foun

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Loucks, Catrina M., Nathan J. Bialas, Martijn P. J. Dekkers, et al. "PACRG, a protein linked to ciliary motility, mediates cellular signaling." Molecular Biology of the Cell 27, no. 13 (2016): 2133–44. http://dx.doi.org/10.1091/mbc.e15-07-0490.

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Cilia are microtubule-based organelles that project from nearly all mammalian cell types. Motile cilia generate fluid flow, whereas nonmotile (primary) cilia are required for sensory physiology and modulate various signal transduction pathways. Here we investigate the nonmotile ciliary signaling roles of parkin coregulated gene (PACRG), a protein linked to ciliary motility. PACRG is associated with the protofilament ribbon, a structure believed to dictate the regular arrangement of motility-associated ciliary components. Roles for protofilament ribbon–associated proteins in nonmotile cilia and

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Francis, Richard J. B., Bishwanath Chatterjee, Niki T. Loges, Hanswalter Zentgraf, Heymut Omran, and Cecilia W. Lo. "Initiation and maturation of cilia-generated flow in newborn and postnatal mouse airway." American Journal of Physiology-Lung Cellular and Molecular Physiology 296, no. 6 (2009): L1067—L1075. http://dx.doi.org/10.1152/ajplung.00001.2009.

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Mucociliary clearance in the adult trachea is well characterized, but there are limited data in newborns. Cilia-generated flow was quantified across longitudinal sections of mouse trachea from birth through postnatal day (PND) 28 by tracking fluorescent microsphere speed and directionality. The percentage of ciliated tracheal epithelial cells, as determined by immunohistochemistry, was shown to increase linearly between PND 0 and PND 21 ( R2 = 0.94). While directionality measurements detected patches of flow starting at PND 3, uniform flow across the epithelia was not observed until PND 7 at a

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Smith, David J., Thomas D. Montenegro-Johnson, and Susana S. Lopes. "Symmetry-Breaking Cilia-Driven Flow in Embryogenesis." Annual Review of Fluid Mechanics 51, no. 1 (2019): 105–28. http://dx.doi.org/10.1146/annurev-fluid-010518-040231.

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The systematic breaking of left–right body symmetry is a familiar feature of human physiology. In humans and many animals, this process originates with asymmetric fluid flow driven by rotating cilia, occurring in a short-lived embryonic organizing structure termed the node. The very low–Reynolds number fluid mechanics of this system is reviewed; important features include how cilia rotation combines with tilt to produce asymmetric flow, boundary effects, time dependence, and the interpretation of particle tracking experiments. The effect of perturbing cilia length and number is discussed and c

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Dissertations / Theses on the topic "Cilia/physiology"

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Muntean, Brian. "Roles of Primary Cilia in Cardiovascular and Renal Physiology." University of Toledo Health Science Campus / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=mco1396014586.

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Bhattarai, Samip Ram. "Characteristics of Primary Cilia and Centrosomes in Neuronal and Glial Lineages of the Adult Brain." Thesis, University of North Texas, 2015. https://digital.library.unt.edu/ark:/67531/metadc801939/.

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Primary cilia are sensory organelles that are important for initiating cell division in the brain, especially through sonic hedgehog (Shh) signaling. Several lines of evidence suggest that the mitogenic effect of Shh requires primary cilia. Proliferation initiated by Shh signaling plays key roles in brain development, in neurogenesis in the adult hippocampus, and in the generation of glial cells in response to cortical injury. In spite of the likely involvement of cilia in these events, little is known about their characteristics. Centrosomes, which are associated with primary cilia, also have

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Bright, Alison R. "A Role for Intraflagellar Transport Proteins in Mitosis: A Dissertation." eScholarship@UMMS, 2013. https://escholarship.umassmed.edu/gsbs_diss/682.

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Disruption of cilia proteins results in a range of disorders called ciliopathies. However, the mechanism by which cilia dysfunction contributes to disease is not well understood. Intraflagellar transport (IFT) proteins are required for ciliogenesis. They carry ciliary cargo along the microtubule axoneme while riding microtubule motors. Interestingly, IFT proteins localize to spindle poles in non-ciliated, mitotic cells, suggesting a mitotic function for IFT proteins. Based on their role in cilia, we hypothesized that IFT proteins regulate microtubule-based transport during mitotic spindle asse

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Bright, Alison R. "A Role for Intraflagellar Transport Proteins in Mitosis: A Dissertation." eScholarship@UMMS, 2006. http://escholarship.umassmed.edu/gsbs_diss/682.

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Disruption of cilia proteins results in a range of disorders called ciliopathies. However, the mechanism by which cilia dysfunction contributes to disease is not well understood. Intraflagellar transport (IFT) proteins are required for ciliogenesis. They carry ciliary cargo along the microtubule axoneme while riding microtubule motors. Interestingly, IFT proteins localize to spindle poles in non-ciliated, mitotic cells, suggesting a mitotic function for IFT proteins. Based on their role in cilia, we hypothesized that IFT proteins regulate microtubule-based transport during mitotic spindle asse

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Duncan, Robert Keith. "Finite-element analysis of inner ear hair bundles : a parameter study of bundle mechanics /." Thesis, This resource online, 1993. http://scholar.lib.vt.edu/theses/available/etd-09292009-020226/.

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Gilbert, Benjamin Lawrence. "ACF7 DEFICIENCY DOES NOT IMPAIR AUDITORY HAIR CELL DEVELOPMENT OR HEARING FUNCTION." Case Western Reserve University School of Graduate Studies / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=case1619801135718899.

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Books on the topic "Cilia/physiology"

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service), ScienceDirect (Online, ed. Primary cilia. Elsevier/Academic Press, 2009.

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L, Baum Gerald, ed. Cilia, mucus, and mucociliary interactions. Marcel Dekker, 1998.

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A, Bloodgood Robert, ed. Ciliary and flagellar membranes. Plenum Press, 1990.

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Matthias, Salathe, ed. Cilia and mucus: From development to respiritory defense. Dekker, 2001.

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Cilia. Cold Spring Harbor Laboratory Press, 2016.

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Goggolidou, Paraskevi. Cilia. Taylor & Francis Group, 2021.

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Goggolidou, Paraskevi. Cilia: Development and Disease. Taylor & Francis Group, 2018.

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Cilia: Development and Disease. Taylor & Francis Group, 2018.

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Goggolidou, Paraskevi. Cilia: Development and Disease. Taylor & Francis Group, 2018.

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Cilia Motors And Regulation. Academic Press, 2009.

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Book chapters on the topic "Cilia/physiology"

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Jorissen, Mark, and Martine Jaspers. "Cilia, Ciliary Movement, and Mucociliary Transport." In Nasal Physiology and Pathophysiology of Nasal Disorders. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-37250-6_2.

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Jorissen, Mark, and Martine Jaspers. "Cilia, Ciliary Movement, and Mucociliary Transport." In Nasal Physiology and Pathophysiology of Nasal Disorders. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-12386-3_3.

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Pieczynski, Jay N., and Bradley K. Yoder. "Renal Cilia Structure, Function, and Physiology." In Seldin and Giebisch's The Kidney. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-12-381462-3.00011-2.

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Fitzsimons, Lindsey. "An Emerging Role for Primary Cilia of the Renal Glomerulus: Implications and Considerations for Pathogenesis of Glomerular Diseases." In Physiology. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.115307.

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Primary cilia are highly specialized, sensory protrusions elaborated from nearly all eukaryotic cells. Our knowledge of their structure and function continues to evolve, driven by an expanding clinical prevalence of human diseases causally linked to primary cilia-specific, genetic mutations. Such mutations often lead to the translation of malformed, non-functional or even absent ciliary proteins, damage the structural integrity of and/or prevent the elaboration of the cilium entirely, and lead to a spectrum of congenital abnormalities/diseases, termed ciliopathies. In the kidneys, genetic muta

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DENTLER, WILLIAM L. "Cilia and Flagella." In Cytology and Cell Physiology. Elsevier, 1987. http://dx.doi.org/10.1016/b978-0-08-091882-2.50016-6.

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Kaneshiro, Edna S. "Amoeboid Movement, Cilia, and Flagella." In Cell Physiology Source Book. Elsevier, 1995. http://dx.doi.org/10.1016/b978-0-12-656970-4.50051-8.

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Kaneshiro, Edna S., Michael J. Sanderson, and George B. Witman. "Amoeboid Movement, Cilia, and Flagella." In Cell Physiology Source Book. Elsevier, 2001. http://dx.doi.org/10.1016/b978-012656976-6/50149-9.

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Foster, Kenneth W. "Flagella, Cilia, Actin- and Centrin-based Movement." In Cell Physiology Source Book. Elsevier, 2012. http://dx.doi.org/10.1016/b978-0-12-387738-3.00047-0.

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Conference papers on the topic "Cilia/physiology"

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Salman, Huseyin Enes, Natalie Jurisch Yaksi, and Huseyin Cagatay Yalcin. "Computational Modeling of Motile Cilia Generated Cerebral Flow Dynamics in Zebrafish Embryo." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0128.

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Background: Motile cilia are hair-like microscopic structures, which move the fluids along the epithelial surfaces. Cilia cover a wide range of regions in the nervous system, such as the nasal cavity, spinal cord central canal, and brain ventricles. Motile cilia-driven cerebrospinal fluid (CSF) flow in the brain ventricles has an important role in the brain development. Embryos lacking motile cilia develop neurological defects due to altered CSF flow. Aim: To investigate the effect of motile-cilia motion on the altered CSF flow, and to understand the role of CSF flow in the brain development a

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Huang, Brendan K., Mustafa K. Khokha, Michael Loewenberg, and Michael A. Choma. "Towards all-optical quantification of force- and power-based performance metrics in cilia-driven fluid flow physiology (Conference Presentation)." In Optical Techniques in Pulmonary Medicine III, edited by Melissa J. Suter, Stephen Lam, and Matthew Brenner. SPIE, 2016. http://dx.doi.org/10.1117/12.2212563.

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