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Journal articles on the topic 'Cincinnati Children's Hospital Medical Center'

Author: Grafiati

Published: 4 June 2021

Last updated: 29 July 2025

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1

Blanchet, Kevin. "The Comprehensive Weight Management Center at Cincinnati Children's Hospital Medical Center." Bariatric Nursing and Surgical Patient Care 1, no. 4 (2006): 241–45. http://dx.doi.org/10.1089/bar.2006.1.241.

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Balistreri, William F., Alan Jobe, and Thomas F. Boat. "Pediatric Subspecialty Training Fellowships at Cincinnati Children's Hospital Medical Center (CCHMC)." Journal of Pediatrics 147, no. 3 (2005): 277–78. http://dx.doi.org/10.1016/j.jpeds.2005.08.020.

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3

Kottenhahn, Renee K., and Jeffery E. Heck. "Prevalence of Paediatric Skin Diseases in Rural Honduras." Tropical Doctor 24, no. 2 (1994): 87–88. http://dx.doi.org/10.1177/004947559402400224.

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Although review of medical literature suggests that skin disease is a common cause of morbidity in developing countries, there have been few prospective primary care studies to document the prevalence of dermatologic conditions. The goal of this study was to determine the prevalence of paediatric skin diseases in rural Honduras. The study was conducted in October 1992, during a medical mission sponsored by the University of Cincinnati, Children's Hospital Medical Center (Cincinnati) and the Honduran Ministry of Health.

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Qualman, Stephen J., Ronald Jaffe, Kevin E. Bove, and Hector Monforte-Muñoz. "Diagnosis of Hirschsprung Disease Using the Rectal Biopsy: Multi-institutional Survey." Pediatric and Developmental Pathology 2, no. 6 (1999): 588–96. http://dx.doi.org/10.1007/s100249900167.

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Diagnostic pathologists remain uncomfortable with the diagnosis of Hirschsprung disease (HD) via rectal (mucosal/submucosal) biopsy and with performance and interpretation of the associated acetylcholinesterase (AChE) assay. This report details the different diagnostic approaches taken by four major pediatric institutions— Children's Hospital, Columbus, OH; Children's Hospital Medical Center, Cincinnati, OH; Children's Hospital, Pittsburgh, PA; Children's Hospital, Los Angeles, CA—in confirming or excluding the presence of HD. The Columbus approach emphasizes serial morphologic examination of

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Greiner, Mary V., and Sarah J. Beal. "Developing a Health Care System for Children in Foster Care." Health Promotion Practice 19, no. 4 (2017): 621–28. http://dx.doi.org/10.1177/1524839917730045.

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In 2012, the Comprehensive Health Evaluations for Cincinnati’s Kids (CHECK) Center was launched at Cincinnati Children’s Hospital Medical Center to provide health care for over 1,000 children placed into foster care each year in the Cincinnati community. This consultation model clinical program was developed because children in foster care have been difficult to manage in the traditional health care setting due to unmet health needs, missing medical records, cumbersome state mandates, and transient and impoverished social settings. This case study describes the history and creation of the CHEC

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KNAPP, JANE F., M. DENISE DOWD, PETER GUYON STRIEGEL та DAVID STEWARD. "Case records of the Cincinnati Childrenʼs Hospital Medical Center". Pediatric Emergency Care 13, № 1 (1997): 57–60. http://dx.doi.org/10.1097/00006565-199702000-00017.

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7

Reinertsen, J. L. "Interview with James M Anderson, Chief Executive Officer, Cincinnati Children's Hospital Medical Center." Quality and Safety in Health Care 15, no. 6 (2006): 443–44. http://dx.doi.org/10.1136/qshc.2006.021246.

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Peña, Alberto. "Alberto Peña, MD, FAAP, FACS, FRCS (England), FRCS (Edinburgh)." Revista Ecuatoriana de Pediatría 23, no. 4 (2023): 1–34. http://dx.doi.org/10.52011/189.

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ACADEMIC TITLE AND ADDRESSClinical Professor of Surgery. University of Cincinnati College of MedicineFounder Director Colorectal Center for ChildrenCincinnati Children’s Hospital Medical CenterUniversity of Cincinnati College of MedicineDivision of Pediatric Surgery, ML 2023, 3333 Burnet Avenue, Cincinnati, Ohio 45229Phone (513) 636-3240, Fax: (513) 636-3248, Mobile : (513) 8072353 e-mail:alberto.pena@cchmc.org

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9

Britto, Maria T., James M. Anderson, William M. Kent, et al. "Cincinnati Children’s Hospital Medical Center: Transforming Care for Children and Families." Joint Commission Journal on Quality and Patient Safety 32, no. 10 (2006): 541–48. http://dx.doi.org/10.1016/s1553-7250(06)32071-5.

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10

Steuerwald, Wendy, Ian Windmill, Michael Scott, Thomas Evans, and Kathleen Kramer. "Stories From the Webcams: Cincinnati Children's Hospital Medical Center Audiology Telehealth and Pediatric Auditory Device Services." American Journal of Audiology 27, no. 3S (2018): 391–402. http://dx.doi.org/10.1044/2018_aja-imia3-18-0010.

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Purpose The purpose of this manuscript is to describe the regulatory, technological, and training considerations for audiologists investigating telehealth and to offer some examples of audiology services provided through telehealth. Method The authors presented the regulatory components, the technology required for audiology staff and patients, and staff training for the audiology telehealth program at Cincinnati Children's Hospital Medical Center. Four case studies highlighting the successful use of telehealth in providing auditory device services to patients were also presented. Results and

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Santillan, Mark K., Richard C. Becker, David A. Calhoun, et al. "Team Science: American Heart Association’s Hypertension Strategically Focused Research Network Experience." Hypertension 77, no. 6 (2021): 1857–66. http://dx.doi.org/10.1161/hypertensionaha.120.16296.

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In 2015, the American Heart Association awarded 4-year funding for a Strategically Focused Research Network focused on hypertension composed of 4 Centers: Cincinnati Children’s Hospital, Medical College of Wisconsin, University of Alabama at Birmingham, and University of Iowa. Each center proposed 3 integrated (basic, clinical, and population science) projects around a single area of focus relevant to hypertension. Along with scientific progress, the American Heart Association put a significant emphasis on training of next-generation hypertension researchers by sponsoring 3 postdoctoral fellow

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Ramsey, Laura B., Cynthia A. Prows, Kejian Zhang, et al. "Implementation of Pharmacogenetics at Cincinnati Children's Hospital Medical Center: Lessons Learned Over 14 Years of Personalizing Medicine." Clinical Pharmacology & Therapeutics 105, no. 1 (2018): 49–52. http://dx.doi.org/10.1002/cpt.1165.

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13

Flake, Holly, Andrea Meisman, Erin Fontaine, et al. "151 History of Clinical Research Professionals at Cincinnati Children's." Journal of Clinical and Translational Science 8, s1 (2024): 45–46. http://dx.doi.org/10.1017/cts.2024.147.

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OBJECTIVES/GOALS: The Clinical Research Professionals (CRP) group was founded in 2000 by research managers at Cincinnati Children’s Hospital Medical Center (CCHMC) as an avenue to share research processes, ideas, successes, and community. The group has developed and evolved at CCHMC to meet the needs of CRP members. METHODS/STUDY POPULATION: CRP has evolved to meet the needs of the clinical research community at CCHMC. In 2008, monthly education meetings and a Research Educator supported a standardized onboarding process. CRP hosted the inaugural CRP Appreciation Day in 2010 to recognize resea

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Blanchet, Kevin D. "Innovative Programs in Telemedicine: The Mayerson Center for Safe and Healthy Children, Cincinnati Children’s Hospital Medical Center." Telemedicine and e-Health 14, no. 7 (2008): 637–41. http://dx.doi.org/10.1089/tmj.2008.8489.

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Walker, Melanie, Brad W. Warner, Richard J. Brilli, and Brian R. Jacobs. "Cardiopulmonary Compromise Associated With Milk and Molasses Enema Use in Children." Journal of Pediatric Gastroenterology and Nutrition 36, no. 1 (2003): 144–48. http://dx.doi.org/10.1002/j.1536-4801.2003.tb07973.x.

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ABSTRACTObjectiveConstipation is a common childhood problem that frequently confronts pediatric practitioners. When enema treatment is indicated to treat constipation, milk and molasses enemas are sometimes used. Side effects and adverse outcomes have been described with many types of enemas, but not with milk and molasses. The purpose of this study is to describe five children who acutely decompensated after receiving milk and molasses enemas.MethodsRetrospective review of the medical records of children with constipation who received milk and molasses enema with subsequent PICU admission at

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Powell, Adam W., Zachary Ritzenthaler, Katherine W. Powell, Rachel Camper, and Nicholas L. Madsen. "Reaching the paediatric chest pain audience outside of ambulatory clinic using internet-based education." BMJ Paediatrics Open 4, no. 1 (2020): e000778. http://dx.doi.org/10.1136/bmjpo-2020-000778.

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Paediatric chest pain is common, yet there remain significant barriers to educating and reassuring patients and their families. In July 2014, a blog titled 6 Questions to Ask When Your Child Complains of Chest Pain was posted to the Cincinnati Children’s Hospital Medical Center website to help educate children and parents about paediatric chest pain. The enhanced interactions through internet-based resources create the opportunity to address chest pain in a way that both educate and provide reassurance. Through the reassurance, there is the potential to meaningfully reduce patient stress all w

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Evans, Tommy, Timothy Nejman, Erin Stewart, and Ian Windmill. "Increasing Pediatric Audiology Services via Telehealth." Seminars in Hearing 42, no. 02 (2021): 136–51. http://dx.doi.org/10.1055/s-0041-1731694.

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AbstractTelehealth as a means to deliver health care services has been used by physicians for many years, but the use of telehealth in audiology, specifically in pediatrics, has been minimal. Barriers such as licensure, reimbursement, technology, and equipment have been cited as reasons for audiologists not participating in telehealth. However, the COVID-19 pandemic created the need for telehealth services to be widely used to safely increase access to healthcare, and emergent orders helped reduce previous barriers so that audiologists could participate in telehealth service delivery. This art

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Marden, J., C. Santos, T. Schilling, et al. "EP.75Deflazacort or prednisone treatment for Duchenne muscular dystrophy (DMD): real-world outcomes at Cincinnati Children's Hospital Medical Center (CCHMC)." Neuromuscular Disorders 29 (October 2019): S174. http://dx.doi.org/10.1016/j.nmd.2019.06.481.

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19

Burke, Michael, Jennifer Willert, Sunil J. Desai, and Richard Kadota. "Pediatric Treatment Guidelines for Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML): What Are They in Today’s Imatinib Era?" Blood 112, no. 11 (2008): 4399. http://dx.doi.org/10.1182/blood.v112.11.4399.4399.

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Abstract Background: The treatment of pediatric Philadelphia positive (Ph+) chronic myelogenous leukemia (CML) in the era of the tyrosine kinase inhibitors (TKI) continues to evolve with the role of allogeneic hematopoietic cell transplantation (allo-HCT) in these patients becoming more controversial. Imatinib has completely replaced allo-HCT for adult CML patients presenting in first chronic phase, reserving HCT for TKI resistant and/or advanced stage patients (accelerated phase and blast crisis). Whether treatment strategies in 2008 have changed for CML in pediatrics, from heavily allo-HCT b

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Drozda, Debra J., Veronica A. Dawson, Dorothy J. Long, Lisa S. Freson, and Marka Sperling. "Assessment of the Effect of a Comprehensive Diabetes Management Program on Hospital Admission Rates of Children With Diabetes Mellitus." Diabetes Educator 16, no. 5 (1990): 389–93. http://dx.doi.org/10.1177/014572179001600511.

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Admission records at Children's Hospital Medical Center in Cincinnati were reviewed to determine the impact of a compre hensive diabetes management program on selected indicators of health status in children with diabetes mellitus. Two periods were compared: January 1973 through June 1978 (periodA), prior to institution of the program, and July 1978 through December 1987 (period B). Although the number of children admitted with a diagnosis of type I diabetes not associated with DKA or other diagnoses increased by 10 % during these 10 years, the number of children with diabetic ketoacidosis (DK

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Burke, Michael, Jennifer Willert, Sunil J. Desai, and Richard Kadota. "Pediatric Treatment Guidelines for Philadelphia Positive (Ph+) Acute Lymphoblastic Leukemia (ALL): What Are They in today’s Imatinib Era?" Blood 112, no. 11 (2008): 4393. http://dx.doi.org/10.1182/blood.v112.11.4393.4393.

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Abstract Background: The treatment of pediatric Philadelphia positive (Ph+) leukemias in the era of the tyrosine kinase inhibitors (TKI) continues to evolve with the role of allogeneic hematopoietic cell transplantation (allo-HCT) in these high-risk patients becoming more controversial. Ph+ acute lymphoblastic leukemia (ALL) prior to imatinib in both pediatric and adult patients has often involved intensive chemotherapy, including consolidative allo-HCT. Whether treatment strategies in 2008 have changed for these Ph+ leukemias in pediatrics, from heavily allo-HCT based to TKI based medical the

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Witt, Rochelle, Benjamin Wisniewski, Melissa Cole, et al. "0410 Utility of the Urine Drug Screen in Maintenance of Wakefulness Testing Interpretation - A Single-Center, Retrospective Analysis in Pediatric Patients." Sleep 45, Supplement_1 (2022): A183—A184. http://dx.doi.org/10.1093/sleep/zsac079.407.

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Abstract Introduction Accurate assessment of hypersomnia depends upon consideration of several factors, including use of medications that affect alertness and sleep organization. Urine drug screens (UDS) are recommended when assessing hypersomnia, but there is little standardization with respect to screening methods, types of substances detected, and use in maintenance of wakefulness test (MWT) interpretation, in part because there is scant literature relating UDS results to patients’ characteristics, MWT findings and implications. Methods A retrospective analysis was performed in adolescents

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Hong, Richard. "Remarks in honor of Clark Darwin West, MD, in appreciation of his inspirational service to the Children's Hospital Medical Center, Cincinnati, Ohio." Journal of Pediatrics 116, no. 5 (1990): S115—S116. http://dx.doi.org/10.1016/s0022-3476(05)82713-1.

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Marden, Jessica R., Jonathan Freimark, Zhiwen Yao, James Signorovitch, Cuixia Tian, and Brenda L. Wong. "Real-world outcomes of long-term prednisone and deflazacort use in patients with Duchenne muscular dystrophy: experience at a single, large care center." Journal of Comparative Effectiveness Research 9, no. 3 (2020): 177–89. http://dx.doi.org/10.2217/cer-2019-0170.

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Aim: To assess outcomes among patients with Duchenne muscular dystrophy receiving deflazacort or prednisone in real-world practice. Methods: Clinical data for 435 boys with Duchenne muscular dystrophy from Cincinnati Children’s Hospital Medical Center were studied retrospectively using time-to-event and regression analyses. Results: Median ages at loss of ambulation were 15.6 and 13.5 years among deflazacort- and prednisone-initiated patients, respectively. Deflazacort was also associated with a lower risk of scoliosis and better ambulatory function, greater % lean body mass, shorter stature a

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Schreck, Brian, and Alexa Economos. "Perinatal Music Therapy: Using Doppler Recordings to Connect and Create." Music and Medicine 10, no. 1 (2018): 22. http://dx.doi.org/10.47513/mmd.v10i1.575.

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Often the first sound of human life occurs in prenatal care when a Doppler ultrasound devicedetects the baby’s heartbeat. In late 2013 at Cincinnati Children’s Hospital Medical Center, Brian Schreck, MA, MT-BC, piloted an innovative music therapy intervention that involved recording internal sounds of a patient’s life to create music with patients and their families. Many devices were explored and adapted: Doppler ultrasound devices, iPad apps, a constructed stethoscope microphone, an electronic stethoscope with Bluetooth, and other digital stethoscopes to record patients’ hearts beating and l

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Srisinghasongkram, Pornchada, and Narong Simakajornboon. "0787 Sleep Problems and Sleep Disorders in Children with Rubinstein-Taybi Syndrome." SLEEP 46, Supplement_1 (2023): A347. http://dx.doi.org/10.1093/sleep/zsad077.0787.

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Abstract Introduction Rubinstein-Taybi syndrome (RSTS) is a genetic condition which characterized by distinctive facial features, broad and angulated thumbs and halluces, short stature, and moderate-to-severe intellectual disability. Sleep problems have been reported in children with RSTS. However, most studies were case reports in adult population. There is limited information on details about sleep problems in children with RSTS. The purpose of this study was to: (1.) Describe the demographics, clinical presentation of children with RSTS; (2.) Describe polysomnographic findings, sleep diagno

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Kummer, Ann W., Linda Lee, Lindsay Schaadt Stutz, Adam Maroney, and Jennifer Weidenbach Brandt. "The Prevalence of Apraxia Characteristics in Patients with Velocardiofacial Syndrome as Compared with Other Cleft Populations." Cleft Palate-Craniofacial Journal 44, no. 2 (2007): 175–81. http://dx.doi.org/10.1597/05-170.1.

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Objective: The purpose of this study was to assess the oral-motor function of children with a history of cleft lip and palate, cleft palate only, velocardiofacial syndrome, and children with normal oral structures to determine if children with velocardiofacial syndrome have more apraxia characteristics than the other populations have. Design: The Apraxia Profile (Hickman, 1997) was administered to all participants in a prospective study. Setting: The investigation was conducted at Cincinnati Children's Hospital Medical Center. Participants: In this study, 10 children with cleft lip and palate,

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Chimote, Ameet A., Abdulaziz Alshwimi, Martina Chirra, et al. "Molecular mechanisms of dexamethasone-mediated modulation of inflammatory and interferon responses in severe COVID-19 patients." Journal of Immunology 208, no. 1_Supplement (2022): 161.11. http://dx.doi.org/10.4049/jimmunol.208.supp.161.11.

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Abstract Severe COVID-19 is characterized by cytokine storm, an excessive production of pro-inflammatory cytokines, which results in acute lung damage and death. Dexamethasone (Dex), a corticosteroid administered as a standard of care for severe COVID-19, has been shown to reduce the onset of severe complications in these patients. However, the mechanisms underlying the beneficial effects of Dex are poorly understood. We conducted a transcriptomic analysis (NanoString) of peripheral blood mononuclear cells (PBMCs) from COVID-19 patients with mild (no hospitalization) and severe (on ventilator

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Khoury, Jane C., Mekibib Altaye, Shelley Ehrlich, et al. "Does Birthweight Represent Imprinting for Life? Preliminary Findings from the Level and Timing of Diabetic Hyperglycemia in Utero: Transgenerational Effect on Adult Morbidity (TEAM) Study." Reports 3, no. 4 (2020): 36. http://dx.doi.org/10.3390/reports3040036.

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Women with pre-gestational diabetes have a high rate of large for gestational age (LGA) babies compared to women without diabetes. In particular, there is a high rate of asymmetric LGA defined as ponderal index (PI) > 90th percentile for gestational age. We examined the association of birth weight and PI, with body mass index (BMI) and obesity status in adulthood, in a cohort of offspring of women with pre-gestational diabetes. The women participated in the Diabetes in Pregnancy (DiP) study at the University of Cincinnati from 1978 to 1995. The offspring of these women are the cohort partic

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Naarding, Karin J., Harmen Reyngoudt, Erik W. van Zwet, et al. "MRI vastus lateralis fat fraction predicts loss of ambulation in Duchenne muscular dystrophy." Neurology 94, no. 13 (2020): e1386-e1394. http://dx.doi.org/10.1212/wnl.0000000000008939.

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ObjectiveWe studied the potential of quantitative MRI (qMRI) as a surrogate endpoint in Duchenne muscular dystrophy by assessing the additive predictive value of vastus lateralis (VL) fat fraction (FF) to age on loss of ambulation (LoA).MethodsVL FFs were determined on longitudinal Dixon MRI scans from 2 natural history studies in Leiden University Medical Center (LUMC) and Cincinnati Children's Hospital Medical Center (CCHMC). CCHMC included ambulant patients, while LUMC included a mixed ambulant and nonambulant population. We fitted longitudinal VL FF values to a sigmoidal curve using a mixe

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Shott, Sally R., Charles M. Myer, and Robin T. Coton. "Surgical Management of Sialorrhea." Otolaryngology–Head and Neck Surgery 101, no. 1 (1989): 47–50. http://dx.doi.org/10.1177/019459988910100109.

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Sialorrhea is a distressing problem in children with cerebral palsy, in children with other neurologic disorders, and in normal children. The constant need for clothing or bib changes in handicapped patients frequently results in further social isolation and causes normal children to be viewed as “impaired.” The surgical treatment of sialorrhea at Children's Hospital Medical Center, Cincinnati, Ohio, has evolved over the past 5 years. Since 1981, 70 surgical procedures have been performed for drooling at this institution; follow-up information is available on 52 patients. The surgical procedur

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Brady, Cassandra, Bahram Namjou, Stephanie Kennebeck, et al. "Developing an Algorithm to Detect Early Childhood Obesity in Two Tertiary Pediatric Medical Centers." Applied Clinical Informatics 07, no. 03 (2016): 693–706. http://dx.doi.org/10.4338/aci-2016-01-ra-0015.

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SummaryThe objective of this study is to develop an algorithm to accurately identify children with severe early onset childhood obesity (ages 1–5.99 years) using structured and unstructured data from the electronic health record (EHR).Childhood obesity increases risk factors for cardiovascular morbidity and vascular disease. Accurate definition of a high precision phenotype through a standardize tool is critical to the success of large-scale genomic studies and validating rare monogenic variants causing severe early onset obesity.Rule based and machine learning based algorithms were developed

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Kummer, Ann W., Marianne Briggs, and Linda Lee. "The Relationship between the Characteristics of Speech and Velopharyngeal Gap Size." Cleft Palate-Craniofacial Journal 40, no. 6 (2003): 590–96. http://dx.doi.org/10.1597/1545-1569_2003_040_0590_trbtco_2.0.co_2.

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Objective The purpose of this study was to examine the relationship between perceptual characteristics of hypernasality, nasal emission and nasal rustle, and size of the velopharyngeal gap. Design A retrospective medical chart review. Setting Cincinnati Children's Hospital Medical Center. Subjects Subjects were patients of the Craniofacial Anomaly Team. All were between ages 3 and 12 years and diagnosed with velopharyngeal dysfunction secondary to cleft palate ± cleft lip. A total of 173 charts were reviewed. Outcome Measures Speech characteristics were assessed perceptually by an experienced

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Brady, Cassandra C., Vidhu V. Thaker, Todd Lingren, et al. "Suboptimal Clinical Documentation in Young Children with Severe Obesity at Tertiary Care Centers." International Journal of Pediatrics 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/4068582.

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Background and Objectives.The prevalence of severe obesity in children has doubled in the past decade. The objective of this study is to identify the clinical documentation of obesity in young children with a BMI ≥ 99th percentile at two large tertiary care pediatric hospitals.Methods.We used a standardized algorithm utilizing data from electronic health records to identify children with severe early onset obesity (BMI ≥ 99th percentile at age <6 years). We extracted descriptive terms and ICD-9 codes to evaluate documentation of obesity at Boston Children’s Hospital and Cincinnati Children’

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Gurbani, Neepa, Phillip Knollman, Christine Heubi, Guixia Huang, Md Hossain, and Narong Simakajornboon. "0526 Utility of polysomnography in tracheostomy decannulation process in children." Sleep 45, Supplement_1 (2022): A232. http://dx.doi.org/10.1093/sleep/zsac079.523.

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Abstract Introduction Different approaches have been used to assess decannulation readiness including clinical observation with gradual tracheostomy downsizing, capping, and microlaryngoscopy and bronchoscopy. Polysomnograms with tracheostomy capping are being used at some centers prior to decannulation. We have previously shown that polysomnography is an important additional tool to predict successful decannulation. However, this study was based on a relatively small number of children. Thus the aim of this study is to review the polysomnographic features that predict decannulation outcomes i

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Knapke, Jacqueline, Amy Short, Tamilyn Bakas, et al. "2474 Promoting collaboration among researchers: A team science training curriculum." Journal of Clinical and Translational Science 2, S1 (2018): 59. http://dx.doi.org/10.1017/cts.2018.222.

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OBJECTIVES/SPECIFIC AIMS: As multidisciplinary, interdisciplinary, and transdisciplinary research has become imperative to solving the complex problems of contemporary healthcare, teaching researchers how to create and maintain high-functioning and innovative teams has also become paramount. In Fall 2016, the Center for Improvement Science (CIS) core, in collaboration with the Translational Workforce Development (TWD) core, at the Cincinnati Center for Clinical & Translational Science & Training (CCTST) began offering training in Team Science in an effort to better prepare researchers

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Anderson, Jeffrey B., Richard J. Czosek, Timothy K. Knilans, and Bradley S. Marino. "The effect of paediatric syncope on health-related quality of life." Cardiology in the Young 22, no. 5 (2012): 583–88. http://dx.doi.org/10.1017/s1047951112000133.

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AbstractBackgroundSyncope is common in children and adolescents and most commonly represents neurocardiogenic syncope. No information has been reported regarding the effect of syncope on health-related quality of life in children.MethodsThis was a retrospective cohort study of patients seen in the Heart Institute Syncope Clinic at Cincinnati Children's Hospital Medical Center between July, 2009 and June, 2010. Health-related quality of life was assessed using the PedsQL™ tool. PedsQL™ scores were compared with both healthy historical controls and historical controls with chronic illnesses.Resu

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Crandall, Beth, Elizabeth Lerner Papautsky, Anna Grome, Kathy Dressman, James Greenberg, and Maria Geiser. "The Role of Monitor Technicians in Enhancing Alarm Response." Proceedings of the International Symposium on Human Factors and Ergonomics in Health Care 2, no. 1 (2013): 116–22. http://dx.doi.org/10.1177/2327857913021023.

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We report a study of monitor alarm response conducted in the newly designed Transitional Care Center (TCC) at Cincinnati Children’s Hospital Medical Center. A key component of the new TCC design has been the development and implementation of a Monitor Technician (MT) position. We examined the MT role from a human factors perspective, with particular focus on the MT’s coordination and communication with nurses (RNs) and respiratory therapists (RTs). We conducted observations and Cognitive Task Analysis interviews of MTs, RNs, and RTs. In this paper, we describe the value of the MT’s role and de

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Bareja, Rohan, Marwa Ismail, Douglas Martin, et al. "NIMG-88. A TRANSFER LEARNING APPROACH FOR AUTOMATIC SEGMENTATION OF TUMOR SUB-COMPARTMENTS IN PEDIATRIC MEDULLOBLASTOMA USING MULTIPARAMETRIC MRI: PRELIMINARY FINDINGS." Neuro-Oncology 24, Supplement_7 (2022): vii185—vii186. http://dx.doi.org/10.1093/neuonc/noac209.706.

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Abstract PURPOSE Superior outcomes for medulloblastoma (MB) requires precise surgical resection which can be guided by tumor segmentation. We present the first attempt at automatic segmentation of MB tumors via a hierarchical transfer-learning model that (1) segments the entire tumor habitat (enhancing tumor (ET), necrosis/non-enhancing tumor (NET), edema), followed by (2) training separate models for each of the sub-compartments. Transfer learning from adult brain tumors is used to optimize segmentation of tumor sub-compartments for pediatric MB. METHODS We evaluated 300 adult glioma studies

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Jacobs, Brian R., Craig K. Hallstrom, Kim Ward Hart, Daniela Mahoney, and Gayle Lykowski. "Lessons from a Successful Implementation of a Computerized Provider Order Entry System." Journal of Pediatric Pharmacology and Therapeutics 12, no. 2 (2007): 102–14. http://dx.doi.org/10.5863/1551-6776-12.2.102.

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OBJECTIVES The electronic health record (EHR) can improve patient safety, care efficiency, cost effectiveness and regulatory compliance. Cincinnati Children's Hospital Medical Center (CCHMC) has successfully implemented an Integrating Clinical Information System (ICIS) that includes Computerized Provider Order Entry (CPOE). This review describes some of the unanticipated challenges and solutions identified during the implementation of ICIS. METHODS Data for this paper was derived from user-generated feedback within the ICIS. Feedback reports were reviewed and placed into categories based on ro

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Shah, Anita N., Katherine A. Auger, Heidi J. Sucharew, et al. "Effect of Parental Adverse Childhood Experiences and Resilience on a Child’s Healthcare Reutilization." Journal of Hospital Medicine 15, no. 11 (2020): 645–51. http://dx.doi.org/10.12788/jhm.3396.

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BACKGROUND: Adverse childhood experiences (ACEs) are associated with poor health outcomes in adults. Resilience may mitigate this effect. There is limited evidence regarding how parents’ ACEs and resilience may be associated with their children’s health outcomes. OBJECTIVE: To determine the association of parental ACEs and resilience with their child’s risk of unanticipated healthcare reutilization. DESIGN, SETTING, AND PARTICIPANTS: We conducted a prospective cohort study (August 2015 to October 2016) at a tertiary, freestanding pediatric medical center in Cincinnati, Ohio. Eligible participa

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Workman, Brandon, Andrew F. Beck, Nicholas C. Newman, and Laura Nabors. "Evaluation of a Program to Reduce Home Environment Risks for Children with Asthma Residing in Urban Areas." International Journal of Environmental Research and Public Health 19, no. 1 (2021): 172. http://dx.doi.org/10.3390/ijerph19010172.

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Pediatric asthma morbidity is often linked to challenges including poor housing quality, inability to access proper medical care, lack of medications, and poor adherence to medical regimens. Such factors also propagate known disparities, by race and income, in asthma-related outcomes. Multimodal home visits have an established evidence base in support of their use to improve such outcomes. The Collaboration to Lessen Environmental Asthma Risks (CLEAR) is a partnership between the Cincinnati Children’s Hospital Medical Center and the local health department which carries out home visits to prov

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Runyan, Christopher M., Armando Uribe-Rivera, Audrey Karlea, et al. "Cost Analysis of Mandibular Distraction versus Tracheostomy in Neonates with Pierre Robin Sequence." Otolaryngology–Head and Neck Surgery 151, no. 5 (2014): 811–18. http://dx.doi.org/10.1177/0194599814542759.

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Objective To evaluate costs associated with surgical treatment for neonates with Pierre Robin sequence (PRS). Study Design Retrospective cohort study. Setting Cincinnati Children’s Hospital Medical Center. Subjects and Methods With Institutional Review Board approval, we retrospectively studied neonates with PRS treated from 2001 to 2009 with either tracheostomy (Trach), mandibular distraction (MD), or Trach with subsequent MD (Trach+MD). Actual charges over a 3-year period associated with operative costs, hospital stay, imaging and sleep studies, clinic visits, and related emergency room visi

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Castillo, Jonathan, Linda M. Goldenhar, Raymond C. Baker, Robert S. Kahn, and Thomas G. DeWitt. "Reflective Practice and Competencies in Global Health Training: Lesson for Serving Diverse Patient Populations." Journal of Graduate Medical Education 2, no. 3 (2010): 449–55. http://dx.doi.org/10.4300/jgme-d-10-00081.1.

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Abstract Background Resident interest in global health care training is growing and has been shown to have a positive effect on participants' clinical skills and cultural competency. In addition, it is associated with career choices in primary care, public health, and in the service of underserved populations. The purpose of this study was to explore, through reflective practice, how participation in a formal global health training program influences pediatric residents' perspectives when caring for diverse patient populations. Methods Thirteen pediatric and combined-program residents enrolled

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Pandey, Manoj K., Albert Frank Magnusen, Vyoma Snehal Trivedi та ін. "Acid β-glucosidase insufficiency activates the C-X-C Motif Chemokine Ligand 9/CXCR3 axis leading to T cell mediated inflammation in Gaucher disease". Journal of Immunology 208, № 1_Supplement (2022): 166.01. http://dx.doi.org/10.4049/jimmunol.208.supp.166.01.

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Abstract Gaucher disease (GD) is caused by GBA1 mutations that lead to decreased activity of lysosomal acid β-glucosidase and abnormal tissue accumulation of its substrate, glucosylceramide (GC). Monocyte lineage cells, e.g., macrophages (Mφs) and dendritic cells (DCs) are prominent disease effectors due to their massive accumulation of GC resulting in “Gaucher cells.” Interaction of Gaucher cells and T lymphocytes trigger massive secretion of IFNγ, TNFα, IL6, IL12p40, IL12p70, IL23, and IL17A/F, that leads to the tissue destruction in GD. The exact mechanisms that trigger excess tissue T cell

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Bruce, Liz. "Cincinnati Children’s Hospital and Boston Medical Centre." Paediatric Nursing 16, no. 5 (2004): 11. http://dx.doi.org/10.7748/paed.16.5.11.s15.

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Daniels, Stephen R., Jennifer M. H. Loggie, Paul T. McEnery, and Richard B. Towbin. "Clinical Spectrum of Intrinsic Renovascular Hypertension in Children." Pediatrics 80, no. 5 (1987): 698–704. http://dx.doi.org/10.1542/peds.80.5.698.

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In the past two decades, 853 children and adolescents have been evaluated for elevated BP as inpatients and outpatients by the hypertension service at Children's Hospital Medical Center, Cincinnati. Most children with hypertension secondary to coarctation of the aorta and all children with glomerulonephritis are managed by other services and are not included in that total. In a retrospective study, 27 children (3%) were identified as having hypertension secondary to intrinsic renal arterial stenosis. The age at presentation ranged from 5 months to 20 years. The mean BP at that time was 171.6/1

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Jacoby, Gregory P., Linda Lee, Ann W. Kummer, Linda Levin, and Nancy A. Creaghead. "The Number of Individual Treatment Units Necessary to Facilitate Functional Communication Improvements in the Speech and Language of Young Children." American Journal of Speech-Language Pathology 11, no. 4 (2002): 370–80. http://dx.doi.org/10.1044/1058-0360(2002/041).

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The present study was conducted to determine the average number of treatment units needed to achieve improvements in functional communication. The subjects, ages 3 to 6 years, consisted of 234 children who received speech-language pathology services over a two-year period at Children's Hospital Medical Center (CHMC) in Cincinnati, Ohio. Subjects had disorders of articulation and/or language and were rated on all areas of deficit using the ASHA functional communication measures (FCMs) of articulation/intelligibility, spoken language production, and spoken language comprehension. Because many su

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Hathout, Yetrib, Edward Brody, Paula R. Clemens, et al. "Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy." Proceedings of the National Academy of Sciences 112, no. 23 (2015): 7153–58. http://dx.doi.org/10.1073/pnas.1507719112.

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Serum biomarkers in Duchenne muscular dystrophy (DMD) may provide deeper insights into disease pathogenesis, suggest new therapeutic approaches, serve as acute read-outs of drug effects, and be useful as surrogate outcome measures to predict later clinical benefit. In this study a large-scale biomarker discovery was performed on serum samples from patients with DMD and age-matched healthy volunteers using a modified aptamer-based proteomics technology. Levels of 1,125 proteins were quantified in serum samples from two independent DMD cohorts: cohort 1 (The Parent Project Muscular Dystrophy–Cin

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Shah, Amy S., Michael A. Helmrath, Thomas H. Inge, et al. "Study protocol: a prospective controlled clinical trial to assess surgical or medical treatment for paediatric type 2 diabetes (ST2OMP)." BMJ Open 11, no. 8 (2021): e047766. http://dx.doi.org/10.1136/bmjopen-2020-047766.

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IntroductionThe pathophysiology of type 2 diabetes (T2D) in youth differs from adults and conventional medical treatment approaches with lifestyle change, metformin, thiazolidinediones or insulin are inadequate. Metabolic bariatric surgery (MBS) improves multiple health outcomes in adults with T2D. Initial small, uncontrolled studies of Roux-en-Y gastric bypass have also suggested beneficial effects in adolescents. Definitive studies in youth with T2D are lacking, especially with the now more common form of MBS, vertical sleeve gastrectomy (VSG). The surgical or medical treatment for paediatri

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