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1

Melo, Lucy. The role of nitric oxide in the regulation of circadian rhythms. National Library of Canada, 1996.

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2

Murray, Gregory Ward. Seasonality, personality and the circadian regulation of mood. Nova Science, 2005.

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3

Murray, Gregory Ward. Seasonality, personality and the circadian regulation of mood. Nova Science, 2005.

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4

Sutochnye ritmy v metabolizme. Nauch. t͡sentr biologicheskikh issledovaniĭ AN SSSR v Pushchine, 1987.

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5

Gillespie, Julia M. A. Melatonin mediated regulation of gonadotropin-releasing hormone (GnRH): Role of melatonin receptors and circadian rhythms. National Library of Canada, 2002.

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6

Hayes, Nathaniel. Circadian Clock: Regulations, Genetic and External Factors. Nova Science Publishers, Incorporated, 2018.

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7

Turek, Fred, ed. Regulation of Sleep and Circadian Rhythms. CRC Press, 1999. http://dx.doi.org/10.1201/9781420001211.

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8

Jones, Christopher R. Neurobiology of Circadian Rhythms Disorders. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0175.

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Temporal organization of nervous system function includes daily rhythms driven by a molecular-genetic hypothalamic “clock” with an intrinsic period length of approximately (circa) one day (diem). The resulting circadian rhythm influences all aspects of brain function and internally synchronizes the circadian oscillations inherent in all other body tissues. Idiosyncratic circadian characteristics interact with perceived environmental stimuli to determine each individual’s entrainment pattern of external synchronization with the day-night cycle. Idiosyncratic entrainment patterns that may come t
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9

Lugaresi, Elio. Somatic and Autonomic Regulation in Sleep. Springer, 2012.

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10

Regulation of Sleep and Circadian Rhythms (Lung Biology in Health and Disease). Informa Healthcare, 1999.

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11

(Editor), Fred Turek, and Phyllis Zee (Editor), eds. Regulation of Sleep and Circadian Rhythms (Lung Biology in Health and Disease). Informa Healthcare, 2009.

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12

Potter, Gregory D. M., and Eleanor M. Scott. Targeting the circadian system. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198789284.003.0016.

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Circadian (approximately 24-hour) rhythms are generated by a hierarchical system responsible for coordinating behaviour and physiology throughout the 24-hour day. Increasing evidence supports roles for disruption of the circadian system in the development of type 2 diabetes (T2DM) and depression. We outline the key aspects of circadian system regulation, discuss the findings indicating that biological disruption of the circadian system produces various behavioural and metabolic abnormalities, and review human studies which show that environmental disruption of the circadian system contributes
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13

1952-, Portaluppi Francesco, Smolensky Michael H, and New York Academy of Sciences., eds. Time-dependent structure and control of arterial blood pressure. New York Academy of Sciences, 1996.

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14

Burdick, Katherine E., Luz H. Ospina, Stephen J. Haggarty, and Roy H. Perlis. The Neurobiology and Treatment of Bipolar Disorder. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0020.

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Bipolar disorder (BPD) is a severe mood disorder that often has psychotic features. Its most severe forms are more common and significantly more likely to cause disability than originally thought. Studies of high-risk children have found them to be at increased risk for a variety of symptoms and neurobiological abnormalities. In contrast to schizophrenia, there is no formal prodromal syndrome that has been identified, and cognitive abnormalities do not precede the onset of the disorder. Abnormal sleep and circadian rhythms are prominent and have led to intriguing biological models. Neurobiolog
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15

Byrne, John H., ed. The Oxford Handbook of Invertebrate Neurobiology. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780190456757.001.0001.

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Invertebrates have proven to be extremely useful models for gaining insights into the neural and molecular mechanisms of sensory processing, motor control, and higher functions, such as feeding behavior, learning and memory, navigation, and social behavior. Their enormous contribution to neuroscience is due, in part, to the relative simplicity of invertebrate nervous systems and, in part, to the large cells found in some invertebrates, like mollusks. Because of the organizms’ cell size, individual neurons can be surgically removed and assayed for expression of membrane channels, levels of seco
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