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Journal articles on the topic 'Circadian'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Zepeda Ríos, Paola Alexandra, and María Olga Quintana Zavala. "Disincronía circadiana y su efecto sobre parámetros de síndrome metabólico en trabajadores: revisión integradora de la literatura." Enfermería Global 20, no. 2 (2021): 592–613. http://dx.doi.org/10.6018/eglobal.426881.

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Introducción: La pérdida del ritmo circadiano causado por desórdenes del sueño es considerada un factor de riesgo importante para desarrollar enfermedades metabólicas como hiperglicemia y resistencia a la insulina. Objetivo: Analizar la literatura existente referente a estudios sobre disincronía circadiana en trabajadores y su influencia sobre parámetros antropométricos de síndrome metabólico de los mismos.Método: Se realizó una búsqueda en las bases de datos electrónicas EBSCO, Thompson Reuters, PubMed y Scopus, los términos de búsqueda seleccionados fueron: trabajo por turnos, melatonina, co

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2

Pereira, Danyella Silva, Sergio Tufik, and Mario Pedrazzoli. "Moléculas que marcam o tempo: implicações para os fenótipos circadianos." Revista Brasileira de Psiquiatria 31, no. 1 (2009): 63–71. http://dx.doi.org/10.1590/s1516-44462009000100015.

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OBJETIVO: Revisar resumidamente a literatura dos últimos 36 anos de pesquisa em cronobiologia molecular a fim de informar aos profissionais de saúde os avanços obtidos nesta área e os potenciais para aplicação na clínica médica. MÉTODO: Buscas na literatura foram realizadas utilizando as bases de dados PubMed e Scopus usando como palavras-chave "clock genes, circadian rhythms, diurnal preference, delayed sleep phase syndrome, advanced sleep phase syndrome, photoperiod and mood disorder". DISCUSSÃO: Atualmente, o mecanismo molecular da regulação da ritmicidade circadiana é compreendido em grand

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3

Mutiz, España Eliana Marley, Prada Carlos Andrés Clavijo, Torres Jhan Sebastian Saavedra, and López Jonathan Alexander Cerón. "SUEÑO INSUFICIENTE, DESALINEAMIENTO CIRCADIANO Y OBESIDAD: MECANISMOS, IMPACTO METABÓLICO Y ESTRATEGIAS DE SALUD PÚBLICA." revista científico-sanitaria SANUM 9, no. 2 (2025): 40–47. https://doi.org/10.5281/zenodo.15173607.

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La obesidad y los trastornos metabólicos son desafíos globales. Estudios recientes han evidenciado que el sueño insuficiente y el desalineamiento circadiano alteran la regulación energética y hormonal, contribuyendo al desarrollo de estas enfermedades. Explorar los mecanismos fisiopatológicos que vinculan la privación del sueño y la desincronización circadiana con la obesidad, y analizar estrategias de intervención en salud pública. Se realizó una búsqueda sistemática en PubMed, Scopus y Web of Sc

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Mishra, Shital Kumar, Zhaomin Zhong, and Han Wang. "Hundreds of LncRNAs Display Circadian Rhythmicity in Zebrafish Larvae." Cells 10, no. 11 (2021): 3173. http://dx.doi.org/10.3390/cells10113173.

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Long noncoding RNAs (lncRNAs) have been shown to play crucial roles in various life processes, including circadian rhythms. Although next generation sequencing technologies have facilitated faster profiling of lncRNAs, the resulting datasets require sophisticated computational analyses. In particular, the regulatory roles of lncRNAs in circadian clocks are far from being completely understood. In this study, we conducted RNA-seq-based transcriptome analysis of zebrafish larvae under both constant darkness (DD) and constant light (LL) conditions in a circadian manner, employing state-of-the-art

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Bernardi, Fabiana, Ana Beatriz Cauduro Harb, Rosa Maria Levandovski, and Maria Paz Loayza Hidalgo. "Transtornos alimentares e padrão circadiano alimentar: uma revisão." Revista de Psiquiatria do Rio Grande do Sul 31, no. 3 (2009): 170–76. http://dx.doi.org/10.1590/s0101-81082009000300006.

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Este artigo tem como objetivo revisar aspectos relacionados a transtornos alimentares e suas relações com as alterações no ritmo circadiano. Realizou-se uma busca sistematizada das informações nas bases de dados PubMed usando os seguintes descritores: eating disorders, circadian rhythm, night eating syndrome, binge eating disorder e sleep patterns. Os transtornos alimentares, como a síndrome do comer noturno e o transtorno da compulsão alimentar periódica, têm sido considerados e relacionados a um atraso no ritmo circadiano da ingestão alimentar e saciedade prejudicada. Os ritmos circadianos s

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Clark, Gretchen T., Yanlei Yu, Cooper A. Urban, et al. "Circadian control of heparan sulfate levels times phagocytosis of amyloid beta aggregates." PLOS Genetics 18, no. 2 (2022): e1009994. http://dx.doi.org/10.1371/journal.pgen.1009994.

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Alzheimer’s Disease (AD) is a neuroinflammatory disease characterized partly by the inability to clear, and subsequent build-up, of amyloid-beta (Aβ). AD has a bi-directional relationship with circadian disruption (CD) with sleep disturbances starting years before disease onset. However, the molecular mechanism underlying the relationship of CD and AD has not been elucidated. Myeloid-based phagocytosis, a key component in the metabolism of Aβ, is circadianly-regulated, presenting a potential link between CD and AD. In this work, we revealed that the phagocytosis of Aβ42 undergoes a daily circa

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Powell, Weston, Lindsay Clark, Maria White, et al. "0006 Circadian Cyclic Gene Expression in Human Airway Epithelial Cells in Asthma and Viral Infections." SLEEP 47, Supplement_1 (2024): A3. http://dx.doi.org/10.1093/sleep/zsae067.0006.

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Abstract Introduction Cellular circadian rhythms regulate gene expression and innate immune pathways related to airway diseases in animal models of disease. However, circadian regulation of gene expression remains uninvestigated in human airway epithelial cells. Primary human airway epithelial cells can be grown at an air-liquid interface as an ex vivo organotypic model to characterize molecular circadian rhythms in the human airway. Using cells from healthy and donors with disease, we hypothesized that circadian cyclic gene expression would be altered in asthma and would display altered viral

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8

Menaker, M. "CIRCADIAN RHYTHMS: Circadian Photoreception." Science 299, no. 5604 (2003): 213–14. http://dx.doi.org/10.1126/science.1081112.

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9

Harb, Ana Beatriz Cauduro, Wolnei Caumo, Priscila Raupp, and Maria Paz Loayza Hidalgo. "Síndrome do comer noturno: aspectos conceituais, epidemiológicos, diagnósticos e terapêuticos." Revista de Nutrição 23, no. 1 (2010): 127–36. http://dx.doi.org/10.1590/s1415-52732010000100014.

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O comportamento e o padrão alimentar são complexos, envolvendo aspectos metabólicos, fisiológicos e ambientais, e apresentando ritmicidade circadiana, herdada e espécie específica, sendo a humana essencialmente diurna. Este estudo tem como objetivo descrever a Síndrome do Comer Noturno, caracterizada por um atraso circadiano do padrão alimentar, mediado por alterações neuroendócrinas ao estresse. Procedeu-se à revisão da bibliografia existente, a partir do exame de artigos publicados pela literatura internacional nas bases de dados dos sites Pubmed, Lilacs, Sirus, referentes ao período de 1955

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Cenek, Lisa, Liubou Klindziuk, Cindy Lopez, et al. "CIRCADA: Shiny Apps for Exploration of Experimental and Synthetic Circadian Time Series with an Educational Emphasis." Journal of Biological Rhythms 35, no. 2 (2020): 214–22. http://dx.doi.org/10.1177/0748730419900866.

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Circadian rhythms are daily oscillations in physiology and behavior that can be assessed by recording body temperature, locomotor activity, or bioluminescent reporters, among other measures. These different types of data can vary greatly in waveform, noise characteristics, typical sampling rate, and length of recording. We developed 2 Shiny apps for exploration of these data, enabling visualization and analysis of circadian parameters such as period and phase. Methods include the discrete wavelet transform, sine fitting, the Lomb-Scargle periodogram, autocorrelation, and maximum entropy spectr

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Bertolucci, Cristiano, Nicola Cavallari, Ilaria Colognesi, et al. "Evidence for an Overlapping Role of CLOCK and NPAS2 Transcription Factors in Liver Circadian Oscillators." Molecular and Cellular Biology 28, no. 9 (2008): 3070–75. http://dx.doi.org/10.1128/mcb.01931-07.

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ABSTRACT The mechanisms underlying the circadian control of gene expression in peripheral tissues and influencing many biological pathways are poorly defined. Factor VII (FVII), the protease triggering blood coagulation, represents a valuable model to address this issue in liver since its plasma levels oscillate in a circadian manner and its promoter contains E-boxes, which are putative DNA-binding sites for CLOCK-BMAL1 and NPAS2-BMAL1 heterodimers and hallmarks of circadian regulation. The peaks of FVII mRNA levels in livers of wild-type mice preceded those in plasma, indicating a transcripti

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12

Tachinardi, Patricia. "Effects of environmental temperature changes on circadian rhythms." Revista da Biologia 9, no. 3 (2018): 13–18. https://doi.org/10.11606/issn.1984-5154.v9p13-18.

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A maioria dos seres-vivos enfrenta variações diárias e sazonais da temperatura ambiental, as quais afetam processos fisiológicos e bioquímicos. Esta revisão abordará alguns dos efeitos dessas variações sobre os ritmos circadianos de diferentes espécies. Primeiramente será discutido como o oscilador circadiano, que gera esses ritmos, mantém seu período estável, mesmo em diferentes temperaturas. Em seguida, serão apresentados casos em que a informação temporal do ciclo diário de temperatura pode ser processada pelo oscilador, tornando esse ciclo uma pista ambiental importante para a sincronizaçã

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13

Stupfel, M., V. Gourlet, A. Perramon, P. Merat, G. Putet, and L. Court. "Comparison of ultradian and circadian oscillations of carbon dioxide production by various endotherms." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 268, no. 1 (1995): R253—R265. http://dx.doi.org/10.1152/ajpregu.1995.268.1.r253.

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Carbon dioxide emission (VCO2) was computed every 20 min from continuous CO2 concentration recordings taken during 3-30 consecutive days, in strictly controlled environmental conditions, in 54 OF1 mice, 99 Japanese quail, 66 Sprague-Dawley rats, 50 Hartley guinea pigs, 7 chicks, for 7-15 days on 2 Cynomolgus monkeys, and for 24 h on 7 premature infants. This VCO2 shows circadian and ultradian oscillations that were analyzed for frequencies and amplitudes in light-dark 12-h alternation (LD 12:12), continuous light (LL), and continuous dark (DD). Circadians were not always identified or were oft

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Froehlich, Allan C., Chen-Hui Chen, William J. Belden, et al. "Genetic and Molecular Characterization of a Cryptochrome from the Filamentous Fungus Neurospora crassa." Eukaryotic Cell 9, no. 5 (2010): 738–50. http://dx.doi.org/10.1128/ec.00380-09.

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ABSTRACT In plants and animals, cryptochromes function as either photoreceptors or circadian clock components. We have examined the cryptochrome from the filamentous fungus Neurospora crassa and demonstrate that Neurospora cry encodes a DASH-type cryptochrome that appears capable of binding flavin adenine dinucleotide (FAD) and methenyltetrahydrofolate (MTHF). The cry transcript and CRY protein levels are strongly induced by blue light in a wc-1-dependent manner, and cry transcript is circadianly regulated, with a peak abundance opposite in phase to frq. Neither deletion nor overexpression of

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15

Yamanaka, Yujiro. "Chronobiology: Human circadian pacemaker and circadian rhythms." Japanese Journal of Physical Fitness and Sports Medicine 69, no. 4 (2020): 343–50. http://dx.doi.org/10.7600/jspfsm.69.343.

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Milhiet, Vanessa, Bruno Etain, Carole Boudebesse, and Frank Bellivier. "Circadian biomarkers, circadian genes and bipolar disorders." Journal of Physiology-Paris 105, no. 4-6 (2011): 183–89. http://dx.doi.org/10.1016/j.jphysparis.2011.07.002.

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17

Mosier, Alexander E., and Jennifer M. Hurley. "Circadian Interactomics: How Research Into Protein-Protein Interactions Beyond the Core Clock Has Influenced the Model of Circadian Timekeeping." Journal of Biological Rhythms 36, no. 4 (2021): 315–28. http://dx.doi.org/10.1177/07487304211014622.

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The circadian clock is the broadly conserved, protein-based, timekeeping mechanism that synchronizes biology to the Earth’s 24-h light-dark cycle. Studies of the mechanisms of circadian timekeeping have placed great focus on the role that individual protein-protein interactions play in the creation of the timekeeping loop. However, research has shown that clock proteins most commonly act as part of large macromolecular protein complexes to facilitate circadian control over physiology. The formation of these complexes has led to the large-scale study of the proteins that comprise these complexe

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18

Love, Jessica, Jacqueline Lane, Richa Saxena, Frank Scheer, and Gregory Bormes. "0026 Novel home-based circadian phase assessment tool to enhance accessible quality care of circadian rhythm disorders- Circadia Study." SLEEP 46, Supplement_1 (2023): A11—A12. http://dx.doi.org/10.1093/sleep/zsad077.0026.

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Abstract Introduction Circadian rhythm sleep-wake disorders (CRSWDs), shifted timing of physiology with the external environments. CRSWDs, often undiagnosed, can increase risk of cardiometabolic and psychiatric disorders, and may have substantial financial and social impacts. Dim light melatonin onset assay (DLMO), the current gold-standard diagnostic test for CRSWDs is expensive/difficult. We aim to develop a more accessible melatonin assessment. Methods Our DLMO assay kit is low-cost, home-based and self-administered. It contains all necessary components for a home-based DLMO assay, includin

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Love, J., G. Bormes, R. Saxena, F. Scheer, and J. Lane. "Enhancing accessible quality care of circadian rhythm disorders through a novel home-based circadian phase assessment tool - circadia study." Sleep Medicine 115 (February 2024): 54–55. http://dx.doi.org/10.1016/j.sleep.2023.11.186.

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20

Grigsby, Kolter, Courtney Ledford, Tanvi Batish, et al. "Targeting the Maladaptive Effects of Binge Drinking on Circadian Gene Expression." International Journal of Molecular Sciences 23, no. 19 (2022): 11084. http://dx.doi.org/10.3390/ijms231911084.

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Previous studies (1) support a role of circadian genes in regulating alcohol intake, and (2) reveal that harmful alcohol use alters circadian rhythms. However, there is minimal knowledge of the effects of chronic alcohol processes on rhythmic circadian gene expression across brain regions important for circadian biology and alcohol intake. Therefore, the present study sought to test the effects of chronic binge-like drinking on diurnal circadian gene expression patterns in the master circadian pacemaker (SCN), the ventral tegmental area (VTA), and the nucleus accumbens (NAc) in High Drinking i

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21

Powell, Weston T., Lucille M. Rich, Elizabeth R. Vanderwall, Maria P. White, and Jason S. Debley. "Temperature synchronisation of circadian rhythms in primary human airway epithelial cells from children." BMJ Open Respiratory Research 9, no. 1 (2022): e001319. http://dx.doi.org/10.1136/bmjresp-2022-001319.

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IntroductionCellular circadian rhythms regulate immune pathways and inflammatory responses that mediate human disease such as asthma. Circadian rhythms in the lung may also contribute to exacerbations of chronic diseases such as asthma by regulating observed rhythms in mucus production, bronchial reactivity, airway inflammation and airway resistance. Primary human airway epithelial cells (AECs) are commonly used to model human lung diseases, such as asthma, with circadian symptoms, but a method for synchronising circadian rhythms in AECs has not been developed, and the presence of circadian rh

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Jensen, Lasse Dahl, Charlotte Gyllenhaal, and Keith Block. "Circadian angiogenesis." Biomolecular Concepts 5, no. 3 (2014): 245–56. http://dx.doi.org/10.1515/bmc-2014-0009.

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AbstractDaily rhythms of light/darkness, activity/rest and feeding/fasting are important in human physiology and their disruption (for example by frequent changes between day and night shifts) increases the risk of disease. Many of the diseases found to be associated with such disrupted circadian lifestyles, including cancer, cardiovascular diseases, metabolic disorders and neurological diseases, depend on pathological de-regulation of angiogenesis, suggesting that disrupting the circadian clock will impair the physiological regulation of angiogenesis leading to development and progression of

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Consens, Flavia B. "Circadian Rhythm Sleep-Wake Disorders." CONTINUUM: Lifelong Learning in Neurology 29, no. 4 (2023): 1149–66. http://dx.doi.org/10.1212/con.0000000000001287.

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ABSTRACT OBJECTIVE This article provides an overview of advances in the understanding of circadian rhythms and the health implications of circadian disruption. LATEST DEVELOPMENTS Circadian medicine is a relatively new concept, with widespread overlap with many other areas of medicine. Circadian clocks rely on feedback loops that control the expression of many genes. Functional circadian oscillators exist at multiple physiologic levels and facilitate a multimodal clock mechanism. The suprachiasmatic nucleus is the central circadian pacemaker. Peripheral tissues can be entrained by other stimul

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Schroder, Elizabeth A., Mellani Lefta, Xiping Zhang, et al. "The cardiomyocyte molecular clock, regulation of Scn5a, and arrhythmia susceptibility." American Journal of Physiology-Cell Physiology 304, no. 10 (2013): C954—C965. http://dx.doi.org/10.1152/ajpcell.00383.2012.

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The molecular clock mechanism underlies circadian rhythms and is defined by a transcription-translation feedback loop. Bmal1 encodes a core molecular clock transcription factor. Germline Bmal1 knockout mice show a loss of circadian variation in heart rate and blood pressure, and they develop dilated cardiomyopathy. We tested the role of the molecular clock in adult cardiomyocytes by generating mice that allow for the inducible cardiomyocyte-specific deletion of Bmal1 (iCSΔ Bmal1). ECG telemetry showed that cardiomyocyte-specific deletion of Bmal1 (iCSΔ Bmal1−/−) in adult mice slowed heart rate

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Wan, Fangzhu, Zongpu Zhang, Jinsen Zhang, et al. "The Circadian Rhythm Gene Network Could Distinguish Molecular Profile and Prognosis for Glioblastoma." International Journal of Molecular Sciences 26, no. 12 (2025): 5873. https://doi.org/10.3390/ijms26125873.

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Increasing evidence highlights the role of aberrant circadian rhythm gene expression in glioblastoma (GBM) progression, but the impact of the circadian rhythm gene network on GBM molecular profiles and prognosis remains unclear. A total of 1042 GBM samples from six public datasets, TCGA and CGGA, were analyzed, with GBM samples stratified into three circadian core-gene patterns using unsupervised clustering based on the expression profiles of 17 circadian rhythm genes. The Limma R package identified differentially expressed genes (DEGs) among the three patterns, and a secondary clustering syst

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Wang, Xingwei, Yanfei Hu, and Wei Wang. "Comparative Analysis of Circadian Transcriptomes Reveals Circadian Characteristics between Arabidopsis and Soybean." Plants 12, no. 19 (2023): 3344. http://dx.doi.org/10.3390/plants12193344.

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The circadian clock, an endogenous timing system, exists in nearly all organisms on Earth. The plant circadian clock has been found to be intricately linked with various essential biological activities. Extensive studies of the plant circadian clock have yielded valuable applications. However, the distinctions of circadian clocks in two important plant species, Arabidopsis thaliana and Glycine max (soybean), remain largely unexplored. This study endeavors to address this gap by conducting a comprehensive comparison of the circadian transcriptome profiles of Arabidopsis and soybean to uncover t

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Dubey, Sneha. "Circadian Rhythm." International Journal of Nursing Education and Research 7, no. 1 (2019): 112. http://dx.doi.org/10.5958/2454-2660.2019.00022.x.

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Turek, Fred W. "Circadian Rhythms." Hormone Research in Paediatrics 49, no. 3-4 (1998): 109–13. http://dx.doi.org/10.1159/000023155.

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SAMPLES, JULIE F., MARY LOU VAN COTT, CHARLENE LONG, IMOGENE M. KING, and ANGELA KERSENBROCK. "Circadian Rhythms." Nursing Research 34, no. 6 (1985): 377???379. http://dx.doi.org/10.1097/00006199-198511000-00021.

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30

Grant, A. C., and E. P. Roter. "Circadian sneezing." Neurology 44, no. 3, Part 1 (1994): 369. http://dx.doi.org/10.1212/wnl.44.3_part_1.369.

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Benitez, Margarita, and Markus Vogl. "Circadian Capital." Leonardo 43, no. 1 (2010): 10. http://dx.doi.org/10.1162/leon.2010.43.1.10.

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Granada, Adrián E., Trinitat Cambras, Antoni Díez-Noguera, and Hanspeter Herzel. "Circadian desynchronization." Interface Focus 1, no. 1 (2010): 153–66. http://dx.doi.org/10.1098/rsfs.2010.0002.

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The suprachiasmatic nucleus (SCN) coordinates via multiple outputs physiological and behavioural circadian rhythms. The SCN is composed of a heterogeneous network of coupled oscillators that entrain to the daily light–dark cycles. Outside the physiological entrainment range, rich locomotor patterns of desynchronized rhythms are observed. Previous studies interpreted these results as the output of different SCN neural subpopulations. We find, however, that even a single periodically driven oscillator can induce such complex desynchronized locomotor patterns. Using signal analysis, we show how t

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Hines, P. J. "Circadian Rhythms." Science Signaling 7, no. 319 (2014): ec87-ec87. http://dx.doi.org/10.1126/scisignal.2005313.

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Riddihough, G. "Circadian Oscillations." Science Signaling 2, no. 69 (2009): ec157-ec157. http://dx.doi.org/10.1126/scisignal.269ec157.

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Eichner, E. Randy. "Circadian Rhythms." Physician and Sportsmedicine 22, no. 10 (1994): 82–93. http://dx.doi.org/10.1080/00913847.1994.11710504.

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Schwartz, W. J. "Circadian Clockwork." Science 261, no. 5122 (1993): 772–73. http://dx.doi.org/10.1126/science.261.5122.772.

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Lakin-Thomas, Patricia L. "Circadian rhythms." Trends in Genetics 16, no. 3 (2000): 135–42. http://dx.doi.org/10.1016/s0168-9525(99)01945-9.

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Persson, Pontus B., and Anja Bondke Persson. "Circadian rhythms." Acta Physiologica 225, no. 1 (2018): e13220. http://dx.doi.org/10.1111/apha.13220.

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Hastings, Michael H. "Circadian clocks." Current Biology 7, no. 11 (1997): R670—R672. http://dx.doi.org/10.1016/s0960-9822(06)00350-2.

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Merrow, Martha, and Till Roenneberg. "Circadian Clocks." Cell 106, no. 2 (2001): 141–43. http://dx.doi.org/10.1016/s0092-8674(01)00443-3.

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Allada, Ravi. "Circadian Clocks." Cell 112, no. 3 (2003): 284–86. http://dx.doi.org/10.1016/s0092-8674(03)00076-x.

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Merrow, Martha. "Circadian rhythms." FEBS Letters 585, no. 10 (2011): 1383. http://dx.doi.org/10.1016/j.febslet.2011.04.055.

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Vaze, Koustubh M., and Vijay Kumar Sharma. "Circadian rhythms." Resonance 18, no. 7 (2013): 662–72. http://dx.doi.org/10.1007/s12045-013-0085-4.

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Nikhil, K. L., and Vijay Kumar Sharma. "Circadian rhythms." Resonance 18, no. 9 (2013): 832–44. http://dx.doi.org/10.1007/s12045-013-0107-2.

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Vaze, Koustubh M., and Vijay Kumar Sharma. "Circadian rhythms." Resonance 18, no. 11 (2013): 1032–50. http://dx.doi.org/10.1007/s12045-013-0129-9.

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Vaze, Koustubh M., K. L. Nikhil, and Vijay Kumar Sharma. "Circadian rhythms." Resonance 19, no. 2 (2014): 175–89. http://dx.doi.org/10.1007/s12045-014-0020-3.

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Aronson, B. "Circadian rhythms." Brain Research Reviews 18, no. 3 (1993): 315–33. http://dx.doi.org/10.1016/0165-0173(93)90015-r.

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McFadden, E. R. "Circadian rhythms." American Journal of Medicine 85, no. 1 (1988): 2–5. http://dx.doi.org/10.1016/0002-9343(88)90230-6.

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McConnell, John. "Circadian clocks." Lancet 342, no. 8873 (1993): 736. http://dx.doi.org/10.1016/0140-6736(93)91725-2.

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Joo, Eun Yeon. "Circadian Neurobiology." Journal of Korean Sleep Research Society 3, no. 1 (2006): 1–5. http://dx.doi.org/10.13078/jksrs.06001.

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