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1

Halami, Mohammad Yahya. "Circovirus Infection in Cattle." Doctoral thesis, Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-155666.

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Circoviren sind kleine, unbehüllte Viren mit einem einzelsträngigen zirkulären DNA Genom mit eine Größe von 1,7 bis 2,4 kb. Das Porcine Circovirus Typ 2 (PCV2), welches zum Genus Circovirus gehört, ist mit einer Anzahl von Krankheitsmanifestationen verbunden worden, die heute als Porcine Circovirus Assoziierte Krankheiten (PCVAD) zusammengefasst sind. Die PCV2-Infektion bei Rindern ist bis zum jetzigen Zeitpunkt marginal erforscht worden. Serologische Untersuchungen auf Circovirus spezifische Antikörperführten zu widersprüchlichen Ergebnissen. Im Jahr 2007 wurde von der Bovinen Neonatalen Panz
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2

com, khalesi20022002@yahoo, and Bahman Khalesi. "Studies of beak and feather disease virus infection." Murdoch University, 2007. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20071119.90905.

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The circovirus Beak and feather disease virus (BFDV) causes psittacine beak and feather disease (PBFD) that is characterised by a chronic disease process associated with feather abnormalities, beak deformities and eventual death in various species of birds in the order Psittaciformes. This disease is seen in captive and wild psittacine species in Australia and several other countries and is a significant threat to the survival of some endangered psittacine species. This thesis reports on genetic studies that have furthered the understanding of the diversity of BFDV present within Australia. T
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Kirwan, Jennifer Anne. "A GC-TOF-MS metabolomics strategy to investigate porcine circovirus 2 infection in pigs." Thesis, University of Liverpool, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.533998.

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4

Gauger, Phillip C. "Characterization of porcine circovirus type 2a and 2b infection and lesions in gnotobiotic pigs." [Ames, Iowa : Iowa State University], 2008.

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5

Heres, Tiago da Silva. "Caracterização de amostras de pasteurella multocida isoladas de lesões pneumônicas associadas ou não com circovirose em suínos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2009. http://hdl.handle.net/10183/16139.

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A Pasteurella multocida é o agente causador da pasteurelose pulmonar dos suínos, sendo comum a ocorrência dessa infecção associada com o Mycoplasma hyopneumoniae no curso da pneumonia enzoótica. O agente é encontrado em pulmões de várias espécies animais e no homem. A infecção de suínos com o circovírus suíno tipo 2 (PCV2) causa uma forma de infecção sistêmica com profundos efeitos no sistema linfóide, causando prejuízos aos processos normais de defesa e facilitando a instalação de infecções secundárias, incluindo a pneumonia enzoótica complicada pela Pasteurella multocida. O objetivo deste tr
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6

Fort, de Puig Maria. "Characterization of immune responses to porcine circovirus type 2 (PCV2) infection and vaccination in pigs." Doctoral thesis, Universitat Autònoma de Barcelona, 2009. http://hdl.handle.net/10803/5619.

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El Circovirus porcí tipus 2 (PCV2) és l'agent causal de la circovirosi porcina (CP), una malaltia multifactorial que afecta porcs en fases de transició i engreix i que causa importants pèrdues econòmiques a la indústria porcina d'arreu del món. Les característiques histopatològiques de la CP i el fet que els animals malalts pateixin sovint infeccions secundàries i oportunístiques indica que aquesta malaltia implica una greu alteració del sistema immunitari del porc. Durant molts anys, el control de la CP es centrava principalment en la millora d'estratègies de maneig i en el control dels facto
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7

Teixeira, Fernandes Lana. "Microarray-based gene expression analysis in natural and experimental cases of porcine circovirus type 2 infection." Doctoral thesis, Universitat Autònoma de Barcelona, 2015. http://hdl.handle.net/10803/299793.

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La presente Tesis se orientó a la caracterización molecular de la infección causada por PCV2 utilizando la tecnología de los microarrays. Este virus es el agente infeccioso esencial de la enfermedad sistémica (ES) por PCV2, una enfermedad de carácter multifactorial que afecta principalmente a cerdos en las fases de transición y engorde, y es una de las enfermedades porcinas más importantes económicamente a nivel mundial. La tecnología de los microarrays permite la determinación simultánea de los niveles de ARNm de miles de genes y ha sido utilizada en los últimos años para investigar los perfi
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8

Nieto, Blanco David. "Torque teno sus viruses: pathogenesis in co-infection with Porcine circovirus type 2 and humoral immune responses during natural infection of pigs." Doctoral thesis, Universitat Autònoma de Barcelona, 2015. http://hdl.handle.net/10803/327879.

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Los Torque teno sus viruses pertenecen a la familia Anelloviridae, e infectan tanto a cerdos como a jabalíes. En la actualidad, los TTSuVs se dividen en dos géneros, Iotatorquevirus para los TTSuV1, que incluye las especies: TTSuV1a y TTSuV1b; y Kappatorquevirus para los TTSuV2, que incluye las especies: TTSuVk2a y TTSuVk2b. Ambos géneros se caracterizan por tener una organización similar del genoma y por una gran variabilidad genética. Las consecuencias de la infección de los TTSuVs sobre su hospedador no son del todo claras. Ambos géneros se detectan con una prevalencia muy alta, tanto en p
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9

Oliver, Ferrando Salvador. "Effect of Porcine circovirus 2 (PCV2) sow or piglet vaccination in different PCV2 subclinical infection scenarios." Doctoral thesis, Universitat Autònoma de Barcelona, 2017. http://hdl.handle.net/10803/461187.

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La present Tesi doctoral esta formada per tres estudis. El primer estudi va avaluar l'efecte de la vacunació de truges enfront a PCV2 sobre els paràmetres reproductius durant dos cicles gestacionals consecutius. Es van immunitzar 94 truges gestants amb una vacuna comercial enfront a PCV2, i 97 van ser injectades amb una solució salina tamponada amb fosfat (PBS). En el primer cicle reproductiu el tractament va ser aplicat a les 6 i 3 setmanes abans del part, i en el segon cicle es va aplicar una dosi de record o PBS a les 2 setmanes abans del part. Les truges vacunades van mostrar nivells d'ant
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10

Trible, Benjamin R. "Expression of recombinant porcine circovirus 2 (PCV2) capsid polypeptides for mapping antibody epitopes following vaccination, infection, and disease." Thesis, Kansas State University, 2012. http://hdl.handle.net/2097/13350.

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Master of Science<br>Department of Diagnostic Medicine/Pathobiology<br>Raymond R. R. Rowland<br>Open reading frame 2 (ORF2) of porcine circovirus type 2 (PCV2) codes for the 233 amino acid capsid protein (CP). Baculovirus-based vaccines that express only ORF2 are protective against clinical disease following experimental challenge or natural infection. The goal of this study was to identify regions in CP preferentially recognized by sera from experimentally infected and vaccinated pigs, and compare these responses to pigs diagnosed with porcine circovirus-associated disease (PCVAD). The app
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11

Halami, Mohammad Yahya [Verfasser], Thomas [Akademischer Betreuer] Vahlenkamp, Thomas [Gutachter] Vahlenkamp, Hermann [Akademischer Betreuer] Müller, Hermann [Gutachter] Müller, and Annette [Gutachter] Mankertz. "Circovirus Infection in Cattle / Mohammad Yahya Halami ; Gutachter: Thomas Vahlenkamp, Hermann Müller, Annette Mankertz ; Thomas Vahlenkamp, Hermann Müller." Leipzig : Universitätsbibliothek Leipzig, 2014. http://d-nb.info/1239421737/34.

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12

Bezerril, Juliana Evangelista. "Avaliação da co-infecção do circovirus suíno 2 com Mycoplasma hyopneumoniae em amostras de pulmões coletadas em abatedouro." Universidade Federal de Viçosa, 2009. http://locus.ufv.br/handle/123456789/5006.

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Made available in DSpace on 2015-03-26T13:46:46Z (GMT). No. of bitstreams: 1 texto completo.pdf: 618598 bytes, checksum: 78e08690fd4db366e1e37fe332d558bc (MD5) Previous issue date: 2009-02-27<br>The porcine circovirus, caused by the porcine circuvirus type 2 (PCV 2), and the porcine enzootic pneumonia, caused by the Mycoplasma hyopneumoniae, are infectious contagious diseases of great importance for worldwide swine production, both causes pneumonias with different presentation patterns. They have cosmopolite distribution and are among the major causes in economic losses. This work was made a
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13

Hasslung, Wikström Frida. "Interaction between porcine circovirus type 2 and the immune system of the pig : with special reference to immunomodulatory sequences in the viral genome /." Uppsala : Dept. of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, 2008. http://epsilon.slu.se/200829.pdf.

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14

Ober, Rebecca Ariel. "Pre and post-infection microbiome associations with weight gain in pigs co-infected with porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2)." Thesis, Kansas State University, 2017. http://hdl.handle.net/2097/38431.

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Master of Science<br>Department of Diagnostic Medicine and Pathology<br>Megan Niederwerder<br>Evidence has shown that the gastrointestinal microbiome plays an important role in response to infectious disease. Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2) are two of the most important pathogens affecting the swine industry worldwide. Co-infections are common on a global scale, resulting in pork production losses through reducing weight gain and causing respiratory disease in growing pigs. Our initial microbiome work demonstrated that the fecal
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15

Teixeira, Thais Fumaco. "Detecção de possíveis agentes virais associados à circovirose suína." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/13371.

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O Circovirus suíno tipo 2 (PCV2) é um vírus ubíquo que tem sido associado a um número de síndromes em suínos. Entre elas, a Síndrome Multissistêmica do Definhamento dos Suínos (SMDS) tornou-se uma das principais causas de perdas econômicas na suinocultura nacional. No entanto, existe incerteza se o PCV2 é, de fato, o único agente responsável por esse quadro, essencialmente porque a administração isolada do vírus a animais suscetíveis não tem sido capaz de reproduzir experimentalmente a síndrome. Em vista disso, um número de outros agentes infecciosos (e não infecciosos) tem sido examinados e s
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16

Núñez, Hernández Fernando. "Identification and characterization of microRNAs in porcine circovirus type 2 and African swine fever virus infections in vivo." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/399553.

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Cuatro estudios diferentes fueron llevados a cabo con el fin de analizar la expresión de microRNAs (miRNAs) porcinos y virales en dos infecciones in vivo diferentes con circovirus porcino tipo 2 (PCV2) y el virus de la peste porcina africana (VPPA). El objetivo del primer estudio fue identificar el patrón de expresión de miRNAs en cerdos infectados y no infectados con PCV2. Para ello, se llevó a cabo una infección experimental y se construyeron librerías de ARN de pequeño tamaño de tonsila y linfonodo mediastínico de estos animales. La secuenciación masiva determinó diferencias de expre
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17

Angobe, Aune Tuyoleni. "Development of a plant-made immunoassay for the detection of Porcine circovirus infections in South African swine herds." Master's thesis, Faculty of Science, 2021. http://hdl.handle.net/11427/33629.

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Porcine circovirus type 2 (PCV-2) is considered the major cause of porcine circovirusassociated diseases and is one of the major pathogens in swine producing countries. PCV-2 is a non-enveloped virus with a single stranded circular DNA genome of about 1.8 kb. This encodes the single capsid protein (CP) which is highly immunogenic, as well as a replication-associated protein. Recombinantly expressed CP can selfassemble into virus-like particles (VLPs) that are structurally and immunogenically very similar to native virions. Current commercially available diagnostic kits are VLPbased and are eff
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18

Chen, Chiou-Lin, and 陳秋麟. "Goose Circovirus Infection and Its Pathogens in Taiwan." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/26881368599564698973.

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博士<br>國立中興大學<br>獸醫學系<br>92<br>In September 2001, adult geese (White Roman geese) in many farms located at southwest coast of Taiwan exhibited feathering disorder and stunted growth. According the symptoms observed, circovirus or circovirus-like virus infection was suspected, and this suspicion was verified by PCR amplification of circovirus-specific sequences from the tissue homogenates of affected geese. Sequence analysis of the 388 bp fragment showed that this sequence matched the genomic sequence of goose circovirus(GCV)deposited in GenBank (95% identity) . This result showed that the geese
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19

Lin, Chih-Yen, and 林志諺. "Pathological and Etiological Studies on Goose Circovirus Infection in Taiwan." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/08297957430643766948.

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碩士<br>國立屏東科技大學<br>獸醫學系<br>93<br>Immunosuppression associated with goose circovirus infection ( GCV ) serves as a predisposing factor for bacterial and fungal infection, which subsequently leads to increase mortality and heavy economic loss. We use the histopathology, polymerase chain reaction ( PCR ), and electronic microscopy to detect GCV and establish a rapidly diagnostic technique. The liver, bursa of Fabouris, thymus and kidney of the 63 cases ( 6 farms ) are collected for histopathologic examinate and virus detection. Tissue emulsion is mode and stored at -70℃. DNeasy tissue kit is used
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20

Chun, Wang, and 王群. "Genotype Analysis and Antibody Prevalence of Porcine Circovirus Infection in Taiwan." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/41114588123086169687.

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碩士<br>國立臺灣大學<br>獸醫學研究所<br>90<br>Genotype Analysis and Antibody Prevalence of Porcine Circovirus Infection in Taiwan Abstract Porcine circovirus (PCV) is one of the most important swine viral diseases. Totally 375 pig tissue samples of tonsils, lymph nodes, and lungs were collected from 71 farms located at the northern, central, southern, and eastern. Virus isolation, Polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) was used to detect PCV in porcine samples. The results indicated that 2 out of 370 samples (0.5%) and 2 out of 71 farms (2.8
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Lin, Chun-Ming, and 林俊明. "Characterization of porcine circovirus type 2 infection in immune cells and lymphoid organs by using in vitro and in vivo models." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/24526321160918095898.

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博士<br>國立臺灣大學<br>獸醫學研究所<br>100<br>Porcine circovirus type 2 (PCV2) is a small, non-enveloped, single-stranded, circular DNA virus, and the infection of PCV2 is distributed in swine population worldwide. Experimental and field studies indicate that PCV2 is a required but insufficient causative agent of postweaning multisystemic wasting syndrome (PMWS), a disease that has a significant impact on swine production. The characteristic feature of PMWS is the presence of high levels of PCV2 antigens and nucleic acid in the lymphoid system along with variable lymphoid depletion and granulomatous inflam
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22

Lai, Ying-Jun, and 賴盈君. "Effect of Cell Maturation on the Susceptibility of Peripheral Blood Monocytes of Healthy Porcine Circovirus Type II-Carrier Pigs to PCV2 Infection." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/40635561386091846217.

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碩士<br>國立臺灣大學<br>獸醫學研究所<br>96<br>Porcine circovirus type 2 (PCV2) is the primary causative agent of postweaning multisystemic wasting syndrome (PMWS). At present, monocyte/macrophage lineage cells are considered as one of the major target cells; however, no evidence of PCV2 replication has been demonstrated in these cells in vitro. Our previous studies have led to the speculation that PCV2 once enters porcine alveolar macrophages (PAMs) by either passive endocytosis or phagocytosis may start intranuclear translocation and proliferation following lipopolysaccharide (LPS) stimulation. Tissue macr
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23

Alvarez, Fernando. "Création d'un modèle cellulaire des voies respiratoires du porc pour étudier les effets d'une co-infection virale au virus du syndrome reproducteur et respiratoire porcin et au circovirus porcin." Thèse, 2013. http://hdl.handle.net/1866/10767.

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Le circovirus porcin de type 2 (PCV2) est un pathogène majeur pour l’industrie porcine et est associé à une longue liste de maladies associées au circovirus porcin (MACVP). Les premières tentatives pour reproduire ces maladies ont montré que le virus doit être combiné à d’autres agents pathogènes du porc ou à différents stimulants du système immunitaire. De ces agents, le virus du syndrome reproducteur et respiratoire porcin (VSRRP) est celui qui est le plus souvent co-isolé avec le PCV dans les fermes. Une grande partie des efforts faits pour étudier les interactions entre ces deux virus ont
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24

ung, Yu-Shing, and 鍾玉興. "Study on Salmonella choleraesuis and porcine circovirus type -II mixed infections." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/39409992317056287528.

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碩士<br>國立屏東科技大學<br>獸醫學系<br>91<br>Samples from pigs that died from salmonella choleraesuis- and porcine circovirus-suspected infections were cultured to isolate and detect these pathogens. Salmonella nucleic acid was extracted and amplified by polymerase chain reaction (PCR) using specific primers. Examination of the amplified PCR products following electrophoresis in 1.2﹪ agarose gels showed a specific DNA band of 830 bp. Seventy seven samples of 100 salmonella-suspected samples were identified to be salmonella choleraesuis infections. The positive rate was 77﹪(77/100)。Viral nucleic acid extrac
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25

Chen, Ciao-Jin, and 陳巧津. "Construction of infectious clones and development of DNA vaccines for duck circovirus." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/07814260555541959371.

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碩士<br>國立中興大學<br>獸醫微生物學研究所<br>96<br>Duck circovirus (DuCV) infection is an emerging disease of waterfowls. This disease invades the lymphoid organ of ducks and subsequently leads to immune suppression and increased incidence of other infections. The goal of this study is divided into two parts. The first is to construct infectious DNA of DuCV for investigating mechanisms involved in regulation of gene expression of DuCV, whereas the second is to develop DNA vaccine for the control of DuCV. Toward the first goal, we used PCR to amplify the full-length genome of DuCV. After ligation, the amplifie
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26

Chiu, Jui-Yu, and 邱芮瑜. "Molecular Cloning of Recombinant ORF2 and Infectious Clone of Porcine Circovirus Type II." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/77399778243414145956.

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碩士<br>國立臺灣大學<br>獸醫學研究所<br>94<br>Post-weaning multisystemic wasting syndrome (PMWS) becomes a major problem in many pig-producing countries throughout the world. Porcine circovirus type 2 (PCV2) has been identified as an essential component of PMWS. Approximately 83.5% of the pigs in Taiwan were seropositive to PCV2. The open reading frame 2 (ORF2) encoding the major capsid protein with epitopes to induce neutralizing antibodies is the potential target gene for vaccine development in against PCV2 infection. However the difficulty to effectively express ORF2 seems to limit the development of PCV
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27

Lan, Shun-Han, and 藍順瀚. "Construction of infectious clone and functional study of the ORF3 gene from duck circovirus." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/59991094775123078913.

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碩士<br>國立中興大學<br>微生物暨公共衛生學研究所<br>100<br>Infections with duck circovirus (DuCV) are associated with growth retardation and developmental problems in farmed ducks. DuCV invades lymphoid tissues and lead to immunosuppression and an increased probability of secondary infections. This disease has been the cause of considerable economic losses to the duck industry worldwide. Because no in vitro culture system is yet available for propagation of DuCV, the pathogenesis of this virus remains unclear. The availability of infectious clones offers an opportunity for analysis and modification of viral genom
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