Relevant bibliographies by topics / Circular RNA - messenger RNA couple

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Academic literature on the topic 'Circular RNA - messenger RNA couple'

Author: Grafiati
Published: 30 November 2024
Last updated: 31 July 2025

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Journal articles on the topic "Circular RNA - messenger RNA couple"

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Dai, Chenyue, Bing Liu, Shaolei Li, et al. "Construction of a circRNA-miRNA-mRNA Regulated Pathway Involved in EGFR-TKI Lung Adenocarcinoma Resistance." Technology in Cancer Research & Treatment 20 (January 2021): 153303382110568. http://dx.doi.org/10.1177/15330338211056809.

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Objectives: Epidermal growth factor receptor-tyrosine kinase inhibitors are widely used for lung epidermal growth factor receptor-positive lung adenocarcinomas, but acquired resistance is inevitable. Although non-coding RNAs, such as circular RNA and microRNA, are known to play vital roles in epidermal growth factor receptor-tyrosine kinase inhibitor resistance, comprehensive analysis is lacking. Thus, this study aimed to explore the circular RNA-microRNA-messenger RNA regulatory network involved in epidermal growth factor receptor-tyrosine kinase inhibitor resistance. Methods: To identify dif
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Peng, Ziqi, Boyang Xu, and Feng Jin. "Circular RNA hsa_circ_0000376 Participates in Tumorigenesis of Breast Cancer by Targeting miR-1285-3p." Technology in Cancer Research & Treatment 19 (January 1, 2020): 153303382092847. http://dx.doi.org/10.1177/1533033820928471.

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This study was designed to identify novel circular RNAs and the related regulatory axis to provide research targets for the diagnosis and treatment of breast cancer. The circular RNA expression microarray “GSE101123” related to breast cancer was downloaded from the Gene Expression Omnibus database. The differentially expressed circular RNAs between tumor and normal samples were screened using Limma package. The targeted microRNAs of the differentially expressed circular RNAs and the targeted messenger RNAs of the microRNAs were predicted using miRanda and miRWalk, respectively, and a circular
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Begliarzade, S. A., R. I. Tamrazov, E. R. Musaev, and C. Wang. "Circular RNA Expression Profile in Cervical Cancer and Construction of the Circular RNA‑MicroRNA‑Messenger RNA Regulatory Network." Creative surgery and oncology 14, no. 2 (2024): 116–26. http://dx.doi.org/10.24060/2076-3093-2024-14-2-116-126.

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Introduction. Cervical cancer (CC) remains the most common cancer in women worldwide. However, effective and specific biomarkers for the diagnosis and prognosis of cervical cancer are yet to be found. In recent years, the potential of circular RNAs (circRNAs) as new diagnostic, prognostic and therapeutic tools has received much attention. The current study involved an in-depth bioinformatics research to explore the circRNA-microRNA (miRNA)-messenger RNA (mRNA) regulatory network in order to identify important molecular processes and biological pathways supposedly associated with CC. Materials
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Xia, Bing, Tao Hong, Xin He, Xinlan Hu, and Yongbo Gao. "A circular RNA derived from MMP9 facilitates oral squamous cell carcinoma metastasis through regulation of MMP9 mRNA stability." Cell Transplantation 28, no. 12 (2019): 1614–23. http://dx.doi.org/10.1177/0963689719875409.

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Emerging evidence demonstrates that dysregulation of circular RNA is linked to tumorigenesis and aggressive progression. However, its role in oral squamous cell carcinoma remains largely uncharacterized. In this study, we identified a novel metastasis-associated circular RNA, circular matrix metalloproteinase 9 (hsa_circ_0001162, a circular RNA derived from matrix metalloproteinase 9), which was remarkably upregulated in oral squamous cell carcinoma and positively correlated with matrix metalloproteinase 9 expression. Patients with high circular matrix metalloproteinase 9 expression were prone
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Hu, Dongpo, and Kangjing Chen. "Construction of a circRNA-miRNA-mRNA regulatory network in glioblastoma multiforme based on bioinformatics analysis." Medicine 104, no. 19 (2025): e42392. https://doi.org/10.1097/md.0000000000042392.

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This study aimed to investigate the functional roles and molecular regulatory mechanisms of circular RNAs in the development of glioblastoma multiforme. Differentially expressed circular RNAs were identified by integrating RNA sequencing data and circular RNA microarray data from the Gene Expression Omnibus database. CircAtlas and CircInteractome databases were used to predict microRNAs (miRNAs) interacting with these circular RNAs. Survival analysis of the miRNAs was performed using data from the Chinese Glioma Genome Atlas. The miRTarBase database was used to predict miRNA target genes, foll
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Rostain, William, Shensi Shen, Teresa Cordero, Guillermo Rodrigo, and Alfonso Jaramillo. "Engineering a Circular Riboregulator in Escherichia coli." BioDesign Research 2020 (September 14, 2020): 1–9. http://dx.doi.org/10.34133/2020/1916789.

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RNAs of different shapes and sizes, natural or synthetic, can regulate gene expression in prokaryotes and eukaryotes. Circular RNAs have recently appeared to be more widespread than previously thought, but their role in prokaryotes remains elusive. Here, by inserting a riboregulatory sequence within a group I permuted intron-exon ribozyme, we created a small noncoding RNA that self-splices to produce a circular riboregulator in Escherichia coli. We showed that the resulting riboregulator can trans-activate gene expression by interacting with a cis-repressed messenger RNA. We characterized the
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Liu, Tao, Guoru Zhang, Yaling Wang, et al. "Identification of Circular RNA-MicroRNA-Messenger RNA Regulatory Network in Atrial Fibrillation by Integrated Analysis." BioMed Research International 2020 (September 29, 2020): 1–13. http://dx.doi.org/10.1155/2020/8037273.

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Background. Circular RNA (circRNA) is a noncoding RNA that forms a closed-loop structure, and its abnormal expression may cause disease. We aimed to find potential network for circRNA-related competitive endogenous RNA (ceRNA) in atrial fibrillation (AF). Methods. The circRNA, miRNA, and mRNA expression profiles in the heart tissue from AF patients were retrieved from the Gene Expression Omnibus database and analyzed comprehensively. Differentially expressed circRNAs (DEcircRNAs), differentially expressed miRNAs (DEmiRNAs), and differentially expressed mRNAs (DEmRNAs) were identified, followed
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Sun, Xiangjun, Xinfeng Ge, Zhiyong Xu, and Dongfeng Chen. "Identification of circular RNA–microRNA–messenger RNA regulatory network in hepatocellular carcinoma by integrated analysis." Journal of Gastroenterology and Hepatology 35, no. 1 (2019): 157–64. http://dx.doi.org/10.1111/jgh.14762.

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Song, Yan, Ning Hu, Xiaowei Song, and Juhong Yang. "Hsa_Circ_0007841 Enhances Multiple Myeloma Chemotherapy Resistance Through Upregulating ABCG2." Technology in Cancer Research & Treatment 19 (January 1, 2020): 153303382092837. http://dx.doi.org/10.1177/1533033820928371.

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The current researches have reported that circular RNA is an important regulatory factor in the progression of various human disease. However, the function and mechanism of most circular RNAs remain unknown in cancers including multiple myeloma. Our study has confirmed that hsa_circ_0007841 is up regulated in U266 doxorubicin resistant cells (U266R) and 8226 doxorubicin resistant cells (8226R) compared to U266 parent cells (U266P) and 8226 parent cells (8226P). Silence of hsa_circ_0007841 in U266R and 8226R could reduce the half-maximal inhibitory concentration which indicated reduction in che
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Zhou, Wenshuo, Linglei Jiang, Shimiao Liao, et al. "Vaccines’ New Era-RNA Vaccine." Viruses 15, no. 8 (2023): 1760. http://dx.doi.org/10.3390/v15081760.

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RNA vaccines, including conventional messenger RNA (mRNA) vaccines, circular RNA (circRNA) vaccines, and self-amplifying RNA (saRNA) vaccines, have ushered in a promising future and revolutionized vaccine development. The success of mRNA vaccines in combating the COVID-19 pandemic caused by the SARS-CoV-2 virus that emerged in 2019 has highlighted the potential of RNA vaccines. These vaccines possess several advantages, such as high efficacy, adaptability, simplicity in antigen design, and the ability to induce both humoral and cellular immunity. They also offer rapid and cost-effective manufa
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Dissertations / Theses on the topic "Circular RNA - messenger RNA couple"

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Levacher, Corentin. "Le déséquilibre ARΝ messager/ARΝ circulaire : nοuveau biοmarqueur en génétique sοmatique et nοuveau facteur de prédispοsitiοn en génétique cοnstitutiοnnelle?" Electronic Thesis or Diss., Normandie, 2024. http://www.theses.fr/2024NORMR045.

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Les ARN circulaires (ARNcirc), produits du rétro-épissage, sont une nouvelle classe émergente d’ARN impliquée dans diverses maladies et notamment le cancer. Ces ARNcirc, par leurs multiples fonctions, peuvent moduler les niveaux des ARN messagers (ARNm), transcrits linéaires finement régulés. Etant donné que physiologiquement un équilibre s’opère entre ces deux types de transcrits, nous faisons l’hypothèse qu’une perturbation des niveaux de ce couple ARNcirc-ARNm joue un rôle dans la tumorigenèse. Pour tester cette hypothèse, nous avons développé SEALigHTS (Splice and Expression Analyses by ex
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Book chapters on the topic "Circular RNA - messenger RNA couple"

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Rybicki, E. P., and S. Lennox. "Plant virus culture." In Virus Culture. Oxford University PressOxford, 1999. http://dx.doi.org/10.1093/oso/9780199637157.003.0009.

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Abstract Plant viruses are distinct from other major host-related groupings of viruses, such as animal or bacterial viruses, in that they are mostly single-stranded messenger-sense ss(+)RNA viruses, and mostly have simple, non-enveloped virions. There are a large number of types of simple isometric viruses, such as the Bromoviridae, Tombusviridae, and Comoviridae, as well as a wide variety of flexuous filamentous or rodlike types with helical capsid symmetry, such as the Potyviridae, Closteroviridae, and Tobamoviruses (1). There are some exceptions, notably with virus families that span differ
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Myers, Simon R., and Harshad A. Navsaria. "Immunolocalization and RT-PCR for the detection and quantification of growth factor and receptor gene expressi•on." In Growth Factors and Receptors. Oxford University PressOxford, 1998. http://dx.doi.org/10.1093/oso/9780199636471.003.0007.

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Abstract In many research fields that impact directly on clinical medicine (e.g. wound healing) a new emphasis on the examination of human tissue has emerged facilitated by the availability of more sophisticated laboratory techniques. This immediately defines the limiting factor in choosing an assay as the volume of human tissue available. To investigate human growth factor and re ceptor gene expression in any depth, assessment of both protein and messenger RNA (mRNA) for ligand and receptor must be made, in terms both of quantity and of distribution, on small tissue samples. 6 mm punch biopsy
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Journal articles
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