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Journal articles on the topic 'Circulation channels'

Author: Grafiati

Published: 30 May 2022

Last updated: 31 July 2025

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1

Земцовский, Aleksey Zemtsovskiy, Мануковский, and Andrey Manukovskiy. "A mathematical model of the aerodynamics of drying chambers with vertical transverse circulation." Forestry Engineering Journal 5, no. 2 (2015): 131–37. http://dx.doi.org/10.12737/11987.

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In the article, from the standpoint of aerodynamics considered the concept of a mathematical model of the circulation channels marketing chambers of variable cross section with a vertically transverse circulation. Factors affecting the uniformity of the air flow in the pile of lumber. Developed analytical mathematical model of the motion of drying agent on the side channel of variable cross section. Revealed that the parameters of the lateral channel of the drying chamber of variable cross section does not depend on the temperature and humidity of the circulating air, and hence from the &#

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2

Zhong, Hua, Zijian Feng, Zifan Wang, and Yougui Wang. "Revisiting the monetary transmission mechanism via banking from the perspective of credit creation." National Accounting Review 6, no. 1 (2024): 116–47. http://dx.doi.org/10.3934/nar.2024006.

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<abstract> <p>Many transmission channels of monetary policy have been proposed to enrich and deepen the understanding of its mechanisms. However, some channels have not been clarified, particularly for those unconventional quantitative policies implemented after 2008 financial crisis. In this paper, we develop a unified model of a credit economy where bank regulations and decisions and loanable funds market are placed at a central position, while stocks and flows are incorporated with each other to formulate banks' credit creation and circulation. We find that bank regulations can

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Guntur, Divya, Horst Olschewski, Péter Enyedi, Réka Csáki, Andrea Olschewski, and Chandran Nagaraj. "Revisiting the Large-Conductance Calcium-Activated Potassium (BKCa) Channels in the Pulmonary Circulation." Biomolecules 11, no. 11 (2021): 1629. http://dx.doi.org/10.3390/biom11111629.

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Potassium ion concentrations, controlled by ion pumps and potassium channels, predominantly govern a cell′s membrane potential and the tone in the vessels. Calcium-activated potassium channels respond to two different stimuli-changes in voltage and/or changes in intracellular free calcium. Large conductance calcium-activated potassium (BKCa) channels assemble from pore forming and various modulatory and auxiliary subunits. They are of vital significance due to their very high unitary conductance and hence their ability to rapidly cause extreme changes in the membrane potential. The pathophysio

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Lakshmanan, S. P., and Manmohan Pandey. "Numerical Investigation of Startup Instabilities in Parallel-Channel Natural Circulation Boiling Systems." Science and Technology of Nuclear Installations 2010 (2010): 1–8. http://dx.doi.org/10.1155/2010/574195.

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The behaviour of a parallel-channel natural circulation boiling water reactor under a low-pressure low-power startup condition has been studied numerically (using RELAP5) and compared with its scaled model. The parallel-channel RELAP5 model is an extension of a single-channel model developed and validated with experimental results. Existence of in-phase and out-of-phase flashing instabilities in the parallel-channel systems is investigated through simulations under equal and unequal power boundary conditions in the channels. The effect of flow resistance on Type-I oscillations is explored. For

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Li, Chunyan, and James O’Donnell. "The Effect of Channel Length on the Residual Circulation in Tidally Dominated Channels." Journal of Physical Oceanography 35, no. 10 (2005): 1826–40. http://dx.doi.org/10.1175/jpo2804.1.

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Abstract With an analytic model, this paper describes the subtidal circulation in tidally dominated channels of different lengths, with arbitrary lateral depth variations. The focus is on an important parameter associated with the reversal of the exchange flows. This parameter (δ) is defined as the ratio between the channel length and one-quarter of the tidal wavelength, which is determined by water depth and tidal frequency. In this study, a standard bottom drag coefficient, CD = 0.0025, is used. For a channel with δ smaller than 0.6–0.7 (short channels), the exchange flow at the open end has

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Schulz, Elisabeth, Henk M. Schuttelaars, Ulf Gräwe, and Hans Burchard. "Impact of the Depth-to-Width Ratio of Periodically Stratified Tidal Channels on the Estuarine Circulation." Journal of Physical Oceanography 45, no. 8 (2015): 2048–69. http://dx.doi.org/10.1175/jpo-d-14-0084.1.

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AbstractThe dependency of the estuarine circulation on the depth-to-width ratio of a periodically, weakly stratified tidal estuary is systematically investigated here for the first time. Currents, salinity, and other properties are simulated by means of the General Estuarine Transport Model (GETM) in cross-sectional slice mode, applying a symmetric Gaussian-shaped depth profile. The width is varied over four orders of magnitude. The individual along-channel circulation contributions from tidal straining, gravitation, advection, etc., are calculated and the impact of the depth-to-width ratio on

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7

FARACI, FRANK M., and DONALD D. HEISTAD. "Regulation of the Cerebral Circulation: Role of Endothelium and Potassium Channels." Physiological Reviews 78, no. 1 (1998): 53–97. http://dx.doi.org/10.1152/physrev.1998.78.1.53.

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Faraci, Frank M., and Donald D. Heistad. Regulation of the Cerebral Circulation: Role of Endothelium and Potassium Channels. Physiol. Rev. 78: 53–97, 1998. — Several new concepts have emerged in relation to mechanisms that contribute to regulation of the cerebral circulation. This review focuses on some physiological mechanisms of cerebral vasodilatation and alteration of these mechanisms by disease states. One mechanism involves release of vasoactive factors by the endothelium that affect underlying vascular muscle. These factors include endothelium-derived relaxing factor (nitric oxide), pro

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8

Popa, Ioana. "Translation channels." Target. International Journal of Translation Studies 18, no. 2 (2006): 205–28. http://dx.doi.org/10.1075/target.18.2.02pop.

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Focusing on a comparative analysis of the translations in French of literary works from four Eastern European countries (Poland, Czechoslovakia, Hungary and Romania) during the communist period, this article examines the political stakes of the international circulation of literary texts. More precisely, it proposes a model for describing the different modalities of international circulation—referred to here as translation channels—based on the statistical analysis of a relevant set of variables. These channels allow us to present a gradation of the degree of politicization and institutionaliz

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9

Faraci, Frank M., and Christopher G. Sobey. "POTASSIUM CHANNELS AND THE CEREBRAL CIRCULATION." Clinical and Experimental Pharmacology and Physiology 23, no. 12 (1996): 1091–95. http://dx.doi.org/10.1111/j.1440-1681.1996.tb01175.x.

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10

Dellsperger, Kevin C. "POTASSIUM CHANNELS AND THE CORONARY CIRCULATION." Clinical and Experimental Pharmacology and Physiology 23, no. 12 (1996): 1096–101. http://dx.doi.org/10.1111/j.1440-1681.1996.tb01176.x.

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11

Kitazano, Takanari, Setsuro Ibayashi, Tetsuhiko Nagao, Hitonori Takaba, and Masatoshi Fujishima. "Potassium channels and the cerebral circulation." Nosotchu 20, no. 2 (1998): 225–38. http://dx.doi.org/10.3995/jstroke.20.225.

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12

Olschewski, Andrea, Emma L. Veale, Bence M. Nagy, et al. "TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications." European Respiratory Journal 50, no. 5 (2017): 1700754. http://dx.doi.org/10.1183/13993003.00754-2017.

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TWIK-related acid-sensitive potassium channel 1 (TASK-1 encoded by KCNK3) belongs to the family of two-pore domain potassium channels. This gene subfamily is constitutively active at physiological resting membrane potentials in excitable cells, including smooth muscle cells, and has been particularly linked to the human pulmonary circulation. TASK-1 channels are sensitive to a wide array of physiological and pharmacological mediators that affect their activity such as unsaturated fatty acids, extracellular pH, hypoxia, anaesthetics and intracellular signalling pathways. Recent studies show tha

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Tristani-Firouzi, M., E. B. Martin, S. Tolarova, E. K. Weir, S. L. Archer, and D. N. Cornfield. "Ventilation-induced pulmonary vasodilation at birth is modulated by potassium channel activity." American Journal of Physiology-Heart and Circulatory Physiology 271, no. 6 (1996): H2353—H2359. http://dx.doi.org/10.1152/ajpheart.1996.271.6.h2353.

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At birth, pulmonary blood flow rapidly increases 8- to 10-fold, and pulmonary arterial pressure falls by 50% within 24 h. The postnatal adaptation of the pulmonary circulation is mediated, in part, by endothelium-derived nitric oxide (EDNO). Recent studies suggest that EDNO may reduce vascular resistance, in part, by activating K+ channels. We hypothesized that K+ channels modulate the changes in pulmonary hemodynamics associated with birth. To test this hypothesis, we studied the effect of K+ channel inhibition on two separate, but interdependent stimuli: 1) mechanical ventilation with low in

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14

Nagaraj, Chandran, Yingji Li, Bi Tang, et al. "Potassium Channels in the Transition from Fetal to the Neonatal Pulmonary Circulation." International Journal of Molecular Sciences 23, no. 9 (2022): 4681. http://dx.doi.org/10.3390/ijms23094681.

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The transition from the fetal to the neonatal circulation includes dilatation of the pulmonary arteries (PA) and closure of the Ductus Arteriosus Botalli (DAB). The resting membrane potential and various potassium channel activities in smooth muscle cells (SMC) from fetal and neonatal PA and DAB obtained from the same species has not been systematically analyzed. The key issue addressed in this paper is how the resting membrane potential and the whole-cell potassium current (IK) change when PASMC or DABSMC are transitioned from hypoxia, reflecting the fetal state, to normoxia, reflecting the p

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Mauritzen, C., J. Price, T. Sanford, and D. Torres. "Circulation and mixing in the Faroese Channels." Deep Sea Research Part I: Oceanographic Research Papers 52, no. 6 (2005): 883–913. http://dx.doi.org/10.1016/j.dsr.2004.11.018.

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16

Reeve, Helen L., E. Kenneth Weir, Stephen L. Archer, and David N. Cornfield. "A maturational shift in pulmonary K+ channels, from Ca2+ sensitive to voltage dependent." American Journal of Physiology-Lung Cellular and Molecular Physiology 275, no. 6 (1998): L1019—L1025. http://dx.doi.org/10.1152/ajplung.1998.275.6.l1019.

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The mechanism responsible for the abrupt decrease in resistance of the pulmonary circulation at birth may include changes in the activity of O2-sensitive K+ channels. We characterized the electrophysiological properties of fetal and adult ovine pulmonary arterial (PA) smooth muscle cells (SMCs) using conventional and amphotericin B-perforated patch-clamp techniques. Whole cell K+ currents of fetal PASMCs in hypoxia were small and characteristic of spontaneously transient outward currents. The average resting membrane potential (RMP) was −36 ± 3 mV and could be depolarized by charybdotoxin (100

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17

Hernandez, Cristian A., and Eugenin Eliseo. "The Role of Pannexin-1 Channels in HIV and NeuroHIV Pathogenesis." Cells 11, no. 14 (2022): 2245. http://dx.doi.org/10.3390/cells11142245.

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The human immunodeficiency virus-1 (HIV) enters the brain shortly after infection, leading to long-term neurological complications in half of the HIV-infected population, even in the current anti-retroviral therapy (ART) era. Despite decades of research, no biomarkers can objectively measure and, more importantly, predict the onset of HIV-associated neurocognitive disorders. Several biomarkers have been proposed; however, most of them only reflect late events of neuronal damage. Our laboratory recently identified that ATP and PGE2, inflammatory molecules released through Pannexin-1 channels, a

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18

Wang, Weishu, Juan Zhen, Weihui Xu, Jiawei Guo, and Yuxin Zhai. "Numerical Study of Flow Field Optimization for Forebay and Suction Chamber to Solve the Vibration of Pumps in a Parallel Circulation Pumping Station." Machines 10, no. 8 (2022): 680. http://dx.doi.org/10.3390/machines10080680.

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The water inlet channel is an essential component of the thermal power plant’s circulating water system. It primarily arranges the water flow in the channel so that it is introduced into the pump room smoothly, steadily, and uniformly. Significantly, the operation state of the circulating water pump is impacted by the flow condition of the water inlet channel. The coal-fired generating set’s water input channel was chosen as the research object in this work, and the Computational Fluid Dynamics (CFD) Method was used to examine hydraulic issues impacting anomalous vibration of circulating pumps

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19

Hebert, Steven C., Gary Desir, Gerhard Giebisch, and Wenhui Wang. "Molecular Diversity and Regulation of Renal Potassium Channels." Physiological Reviews 85, no. 1 (2005): 319–71. http://dx.doi.org/10.1152/physrev.00051.2003.

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K+ channels are widely distributed in both plant and animal cells where they serve many distinct functions. K+ channels set the membrane potential, generate electrical signals in excitable cells, and regulate cell volume and cell movement. In renal tubule epithelial cells, K+ channels are not only involved in basic functions such as the generation of the cell-negative potential and the control of cell volume, but also play a uniquely important role in K+ secretion. Moreover, K+ channels participate in the regulation of vascular tone in the glomerular circulation, and they are involved in the m

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20

Toyoda, K., K. Fujii, S. Ibayashi, T. Kitazono, T. Nagao, and M. Fujishima. "Role of ATP-sensitive potassium channels in brain stem circulation during hypotension." American Journal of Physiology-Heart and Circulatory Physiology 273, no. 3 (1997): H1342—H1346. http://dx.doi.org/10.1152/ajpheart.1997.273.3.h1342.

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The basilar artery and its branch arterioles dilate actively in response to a marked decrease in blood pressure and maintain cerebral blood flow (CBF) to the brain stem. We tested the hypothesis that ATP-sensitive potassium (KATP) channels play a role in the autoregulatory responses of the brain stem circulation in vivo. In anesthetized Sprague-Dawley rats, local CBF to the brain stem was determined with laser-Doppler flowmetry, and diameters of the basilar artery and branch arterioles were measured through a cranial window during stepwise hemorrhagic hypotension. During topical application of

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21

Barbeau, Solène, Guillaume Gilbert, Guillaume Cardouat, et al. "Mechanosensitivity in Pulmonary Circulation: Pathophysiological Relevance of Stretch-Activated Channels in Pulmonary Hypertension." Biomolecules 11, no. 9 (2021): 1389. http://dx.doi.org/10.3390/biom11091389.

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A variety of cell types in pulmonary arteries (endothelial cells, fibroblasts, and smooth muscle cells) are continuously exposed to mechanical stimulations such as shear stress and pulsatile blood pressure, which are altered under conditions of pulmonary hypertension (PH). Most functions of such vascular cells (e.g., contraction, migration, proliferation, production of extracellular matrix proteins, etc.) depend on a key event, i.e., the increase in intracellular calcium concentration ([Ca2+]i) which results from an influx of extracellular Ca2+ and/or a release of intracellular stored Ca2+. Ca

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Parekh, N., and A. P. Zou. "Role of prostaglandins in renal medullary circulation: response to different vasoconstrictors." American Journal of Physiology-Renal Physiology 271, no. 3 (1996): F653—F658. http://dx.doi.org/10.1152/ajprenal.1996.271.3.f653.

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This study investigated effects of renal prostaglandins and their interaction with different vasoactive agents in regulating regional renal blood flow. Using intravenous infusions, we compared effects of different pressor hormones and a nitric oxide (NO) inhibitor under control conditions and after inhibition of cyclooxygenase. Because vasodilator effects of prostanoids are considered to be mediated via opening of ATP-dependent K+ channels, we also studied effects of a prostacyclin analogue (iloprost), a channel opener (lemakalim), and a channel blocker (glibenclamide). Blood flow in renal cor

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23

Sajwan, Neha. "Review Article: Concept of Srotorodha(Blockage of Channels) in Relation to Aam." International Research Journal of Ayurveda & Yoga 05, no. 05 (2022): 139–43. http://dx.doi.org/10.47223/irjay.2022.5522.

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One of the main reasons of disease is an aggravated dosha. These intensified doshasbecome lodged in channels, resulting in abnormalities or channel obstruction, which leads to a variety of illnesses. Blockage of channels is another key cause of disease, in addition to improper digestive fire and suppression of desire. The tissue elements or constituents undergoing change are transported to their destination via circulatorypathways. The term "channel" refers to the system of circulation. Contaminated diet and regimen are the cause of body and mind channel obstruction. The function and quality o

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Roberts, Christine C., Scott A. Roberts, Martin B. Nemer, and Rekha R. Rao. "Circulation within confined droplets in Hele-Shaw channels." Physics of Fluids 26, no. 3 (2014): 032105. http://dx.doi.org/10.1063/1.4867695.

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Rosenblum, William I. "ATP-Sensitive Potassium Channels in the Cerebral Circulation." Stroke 34, no. 6 (2003): 1547–52. http://dx.doi.org/10.1161/01.str.0000070425.98202.b5.

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26

Zvirin, Yoram. "Natural circulation loops with parallel channels - transient behavior." Nuclear Engineering and Design 84, no. 1 (1985): 73–81. http://dx.doi.org/10.1016/0029-5493(85)90314-0.

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Tripathi, Ashish Kumar, Sushma Rawat, and Shuchi Mitra. "Importance of Srotas (channels of circulation) in pharmacokinetics." JOURNAL OF CONVENTIONAL KNOWLEDGE AND HOLISTIC HEALTH 2, no. 01 (2018): 01–03. http://dx.doi.org/10.53517/jckhh.2581-3331.212018182.

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Pharmacokinetics refers to what happens to a drug from entrance into the body until the exit of all traces. Four processes encompass it namely absorption, distribution, metabolism and excretion. In pharmacokinetics, the Srotas (channels and pathways) has a crucial role. The aim of this study is to critically review the role of Srotas in the pharmacokinetics of drug as per Ayurvedic as well as modern perspective. The most relevant literature based on the Srotas was accessed from the online scientific database as well as from the Ayurvedic classical texts. The literature revealed that the pharma

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Leffler, Charles W., Helena Parfenova, Jonathan H. Jaggar, and Rui Wang. "Carbon monoxide and hydrogen sulfide: gaseous messengers in cerebrovascular circulation." Journal of Applied Physiology 100, no. 3 (2006): 1065–76. http://dx.doi.org/10.1152/japplphysiol.00793.2005.

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This review focuses on two gaseous cellular messenger molecules, CO and H2S, that are involved in cerebrovascular flow regulation. CO is a dilatory mediator in active hyperemia, autoregulation, hypoxic dilation, and counteracting vasoconstriction. It is produced from heme by a constitutively expressed enzyme [heme oxygenase (HO)-2] expressed highly in the brain and by an inducible enzyme (HO-1). CO production is regulated by controlling substrate availability, HO-2 catalytic activity, and HO-1 expression. CO dilates arterioles by binding to heme that is bound to large-conductance Ca2+-activate

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Wang, Mingyang, Qian Yu, Yuan Xu, et al. "A Numerical Study on the Influence of Riparian Vegetation Patch on the Transportation of Suspended Sediment in a U-Bend Channel Flow." Fluids 9, no. 5 (2024): 109. http://dx.doi.org/10.3390/fluids9050109.

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Bend sections are ubiquitous in natural sandy river systems. This study employs Computational Fluid Dynamics–Discrete Phase Model (CFD-DPM) methodology to analyze particle transport dynamics in U-bend channel flows, focusing on the distinctions between partially vegetated (Case No.1) and non-vegetated (Case No.2) scenarios. The research aims to unravel the intricate relationships among bending channel-induced secondary flow, vegetation blockage, and particle aggregation, employing both quantitative and qualitative approaches. (I) The key findings reveal that vegetation near the inner walls of

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Sedivy, Vojtech, Shreena Joshi, Youssef Ghaly, et al. "Role of Kv7 channels in responses of the pulmonary circulation to hypoxia." American Journal of Physiology-Lung Cellular and Molecular Physiology 308, no. 1 (2015): L48—L57. http://dx.doi.org/10.1152/ajplung.00362.2013.

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Hypoxic pulmonary vasoconstriction (HPV) is a beneficial mechanism that diverts blood from hypoxic alveoli to better ventilated areas of the lung, but breathing hypoxic air causes the pulmonary circulation to become hypertensive. Responses to airway hypoxia are associated with depolarization of smooth muscle cells in the pulmonary arteries and reduced activity of K+channels. As Kv7 channels have been proposed to play a key role in regulating the smooth muscle membrane potential, we investigated their involvement in the development of HPV and hypoxia-induced pulmonary hypertension. Vascular eff

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Pires, Paulo W., Carla M. Dams Ramos, Nusrat Matin, and Anne M. Dorrance. "The effects of hypertension on the cerebral circulation." American Journal of Physiology-Heart and Circulatory Physiology 304, no. 12 (2013): H1598—H1614. http://dx.doi.org/10.1152/ajpheart.00490.2012.

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Maintenance of brain function depends on a constant blood supply. Deficits in cerebral blood flow are linked to cognitive decline, and they have detrimental effects on the outcome of ischemia. Hypertension causes alterations in cerebral artery structure and function that can impair blood flow, particularly during an ischemic insult or during periods of low arterial pressure. This review will focus on the historical discoveries, novel developments, and knowledge gaps in 1) hypertensive cerebral artery remodeling, 2) vascular function with emphasis on myogenic reactivity and endothelium-dependen

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Bratz, Ian N., Gregory M. Dick, Johnathan D. Tune, et al. "Impaired capsaicin-induced relaxation of coronary arteries in a porcine model of the metabolic syndrome." American Journal of Physiology-Heart and Circulatory Physiology 294, no. 6 (2008): H2489—H2496. http://dx.doi.org/10.1152/ajpheart.01191.2007.

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Recent studies implicate channels of the transient receptor potential vanilloid family (e.g., TRPV1) in regulating vascular tone; however, little is known about these channels in the coronary circulation. Furthermore, it is unclear whether metabolic syndrome alters the function and/or expression of TRPV1. We tested the hypothesis that TRPV1 mediates coronary vasodilation through endothelium-dependent mechanisms that are impaired by the metabolic syndrome. Studies were conducted on coronary arteries from lean and obese male Ossabaw miniature swine. In lean pigs, capsaicin, a TRPV1 agonist, rela

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Termini, D., and T. Moramarco. "Application of entropic approach to estimate the mean flow velocity and Manning roughness coefficient in a high-curvature flume." Hydrology Research 48, no. 3 (2016): 634–45. http://dx.doi.org/10.2166/nh.2016.106.

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The entropy-based approach allows the estimation of the mean flow velocity in open channel flow by using the maximum flow velocity. The linear relationship between the mean velocity, umax, and the mean flow velocity, um, through the dimensionless parameter Φ(M), has been verified both in natural rivers and in laboratory channels. Recently, the authors of this study investigated the reliability of the entropy-based formula in a straight channel and under different bed and side-walls' roughness conditions. The present study aims to further validate the entropy-based approach and to explore the e

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Piątek, Dawid, Agata Gołąb, and Dominika Wrońska-Wałach. "Changes in erosion processes and morphology of step-pool channels in the ski resort with artificial snowmaking, an example from Gubałowskie foothills." Quaestiones Geographicae 44, no. 1 (2025): 151–56. https://doi.org/10.14746/quageo-2025-0011.

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The construction of ski runs with artificial snowmaking in mountainous areas changes natural water circulation and leads to the activation of erosion and deposition processes. To recognise this relationship, we selected a small catchment in the Gubałowskie Foothills, the Inner Carpathians, where 17% of the area is covered by the ski runs. In our study, we hypostatised that: (i) channels draining ski runs exhibit different morphological and morphometric characteristics compared to those that do not drain ski runs; (ii) the statistical relationships between channel morphometric parameters differ

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Guo, Liwen, Zhihong Kang, Shuaiwei Ding, et al. "A New Algorithm Model Based on Extended Kalman Filter for Predicting Inter-Well Connectivity." Applied Sciences 14, no. 21 (2024): 9913. http://dx.doi.org/10.3390/app14219913.

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Given that more and more oil reservoirs are reaching the high water cut stage during water flooding, the construction of an advanced algorithmic model for identifying inter-well connectivity is crucial to improve oil recovery and extend the oilfield service life cycle. This study proposes a state variable-based dynamic capacitance (SV-DC) model that integrates artificial intelligence techniques with dynamic data and geological features to more accurately identify inter-well connectivity and its evolution. A comprehensive sensitivity analysis was performed on single-well pairs and multi-well gr

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Hu, Xiang-Qun, and Lubo Zhang. "Ca2+-Activated K+ Channels and the Regulation of the Uteroplacental Circulation." International Journal of Molecular Sciences 24, no. 2 (2023): 1349. http://dx.doi.org/10.3390/ijms24021349.

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Adequate uteroplacental blood supply is essential for the development and growth of the placenta and fetus during pregnancy. Aberrant uteroplacental perfusion is associated with pregnancy complications such as preeclampsia, fetal growth restriction (FGR), and gestational diabetes. The regulation of uteroplacental blood flow is thus vital to the well-being of the mother and fetus. Ca2+-activated K+ (KCa) channels of small, intermediate, and large conductance participate in setting and regulating the resting membrane potential of vascular smooth muscle cells (VSMCs) and endothelial cells (ECs) a

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Walker, B. R. "Evidence for uneven distribution of L-type calcium channels in rat pulmonary circulation." American Journal of Physiology-Heart and Circulatory Physiology 269, no. 6 (1995): H2051—H2056. http://dx.doi.org/10.1152/ajpheart.1995.269.6.h2051.

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Experiments were performed on isolated, perfused rat lungs to determine the segmental sites of vasoconstriction in response to factors that open voltage-sensitive, L-type calcium channels on vascular smooth muscle cells. Lungs from male Sprague-Dawley rats were perfused at constant flow with a physiological saline solution (PSS) containing albumin. Measurements were made of pulmonary arterial and venous pressure, whereas capillary pressure was estimated by the double-occlusion technique. After equilibration, lungs were constricted with depolarizing PSS containing high K+ (35 or 45 mM). With bo

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Prasad, Devendra, G. Naga Srinivasulu, Ajaya Bharti, Naveen Kumar, and Syed Mohd Azam. "Experimental Analysis on Flow Field Pattern of PEM Fuel Cells." Materials Science Forum 1065 (June 30, 2022): 179–91. http://dx.doi.org/10.4028/p-nyf254.

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The polymer electrolyte membrane (PEM) fuel cells flow fields channels serve the same roles as nutrient and reactant circulation systems in plants and animals, so bio-inspired flow field channels with a similar could improve reactant uniform transport efficiency and boost fuel cell performance. In this analysis, the lung channel configuration of a humane lung and a tree leaf bio-inspired flow field channels are used as an anode and cathode bipolar plate. A channel model is developed for three new flow field patterns designs: leaf design, lung design and triple-serpentine. It has been observed

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Burchard, Hans, Robert D. Hetland, Elisabeth Schulz, and Henk M. Schuttelaars. "Drivers of Residual Estuarine Circulation in Tidally Energetic Estuaries: Straight and Irrotational Channels with Parabolic Cross Section." Journal of Physical Oceanography 41, no. 3 (2011): 548–70. http://dx.doi.org/10.1175/2010jpo4453.1.

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Abstract The generation of residual circulation in a tidally energetic estuary with constant longitudinal salinity gradient and parabolic cross section is examined by means of a two-dimensional cross-sectional numerical model, neglecting river runoff and Stokes drift. It is shown how the longitudinal and lateral residual circulation can be decomposed into contributions from various processes such as tidal straining circulation, gravitational circulation, advectively driven circulation, and horizontal mixing circulation. The sensitivity of the residual circulation and its components from variou

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Zhang, Qian, Chunyan Li, Wei Huang, Jun Lin, Matthew Hiatt, and Victor H. Rivera-Monroy. "Water Circulation Driven by Cold Fronts in the Wax Lake Delta (Louisiana, USA)." Journal of Marine Science and Engineering 10, no. 3 (2022): 415. http://dx.doi.org/10.3390/jmse10030415.

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Atmospheric cold fronts can periodically generate storm surges and affect sediment transport in the Northern Gulf of Mexico (NGOM). In this paper, we evaluate water circulation spatiotemporal patterns induced by six atmospheric cold front events in the Wax Lake Delta (WLD) in coastal Louisiana using the 3-D hydrodynamic model ECOM-si. Model simulations show that channelized and inter-distributary water flow is significantly impacted by cold fronts. Water volume transport throughout the deltaic channel network is not just constrained to the main channels but also occurs laterally across channel

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Cornfield, D. N., J. A. McQueston, I. F. McMurtry, D. M. Rodman, and S. H. Abman. "Role of ATP-sensitive potassium channels in ovine fetal pulmonary vascular tone." American Journal of Physiology-Heart and Circulatory Physiology 263, no. 5 (1992): H1363—H1368. http://dx.doi.org/10.1152/ajpheart.1992.263.5.h1363.

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To study the potential role of ATP-sensitive K+ (K+ATP) channels in fetal pulmonary vasoregulation, we studied the effect of a K+ATP channel agonist, lemakalim, and antagonist, glibenclamide, on the fetal pulmonary circulation in nine chronically instrumented late-gestation fetal lambs. Left pulmonary artery (LPA) blood flow was measured with an electromagnetic flow transducer. Brief (10 min) infusions of lemakalim at 3, 10, and 30 micrograms/min into the LPA produced dose-dependent increases in flow from 68 +/- 7 to 96 +/- 11, 160 +/- 15, and 204 +/- 34 ml/min, respectively. The duration of p

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Jeffries, Martin O., and M. Amanda Shaw. "The drift of ice islands from the Arctic Ocean into the channels of the Canadian Arctic archipelago: the history of Hobson's Choice Ice Island." Polar Record 29, no. 171 (1993): 305–12. http://dx.doi.org/10.1017/s0032247400023950.

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ABSTRACTThe drift of Hobson's Choice Ice Island from the Arctic Ocean into the channels of the Queen Elizabeth Islands, Northwest Territories, Canadian Arctic, between February 1988 and August 1992, was monitored by a Système Argos satellite-positioning buoy. During the period August 1991 to May 1992, the ice island was imaged by synthetic aperture radar (SAR) aboard the ERS-1 satellite. The buoy data show that Hobson's Choice entered Peary Channel (between Axel Heiberg Island and Ellef Ringnes Island) in October 1988. Subsequently, between mid-August 1991 and November 1991, it drifted rapidly

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Jouen-Tachoire, Thibault R. H., Stephen J. Tucker, and Paolo Tammaro. "Ion channels as convergence points in the pathology of pulmonary arterial hypertension." Biochemical Society Transactions 49, no. 4 (2021): 1855–65. http://dx.doi.org/10.1042/bst20210538.

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Pulmonary arterial hypertension (PAH) is a fatal disease of the cardiopulmonary system that lacks curative treatments. The main pathological event in PAH is elevated vascular resistance in the pulmonary circulation, caused by abnormal vasoconstriction and vascular remodelling. Ion channels are key determinants of vascular smooth muscle tone and homeostasis, and four PAH channelopathies (KCNK3, ABCC8, KCNA5, TRPC6) have been identified so far. However, the contribution of ion channels in other forms of PAH, which account for the majority of PAH patients, has been less well characterised. Here w

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Kao, Yang-Ta, Hsiau-Wen Lin, and Dai-Yi Qiu. "Implementation of Offline Consumer Behavior Tracking." International Journal of Pattern Recognition and Artificial Intelligence 35, no. 09 (2021): 2150028. http://dx.doi.org/10.1142/s0218001421500282.

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Due to declining trading volume growth in e-commerce platforms, physical channels have attracted considerable investments from various large international companies (e.g. Alibaba, JD, Walmart, Wanda, and Wuzhou International). However, e-commerce platforms can track consumers’ behaviors (attraction to landing page design, clicks on certain products, consumer behavior trajectory tracking, clicks on advertisements, and internal link optimization of product pages), a feat unachievable in current physical channels. Consequently, this study attempted to apply the characteristics of online channels

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Olschewski, Andrea, and Edward Kenneth Weir. "Redox Regulation of Ion Channels in the Pulmonary Circulation." Antioxidants & Redox Signaling 22, no. 6 (2015): 465–85. http://dx.doi.org/10.1089/ars.2014.5899.

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Dick, Gregory M., Ian N. Bratz, Léna Borbouse, et al. "Voltage-dependent K+ channels regulate the duration of reactive hyperemia in the canine coronary circulation." American Journal of Physiology-Heart and Circulatory Physiology 294, no. 5 (2008): H2371—H2381. http://dx.doi.org/10.1152/ajpheart.01279.2007.

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We previously demonstrated a role for voltage-dependent K+ (KV) channels in coronary vasodilation elicited by myocardial metabolism and exogenous H2O2, as responses were attenuated by the KV channel blocker 4-aminopyridine (4-AP). Here we tested the hypothesis that KV channels participate in coronary reactive hyperemia and examined the role of KV channels in responses to nitric oxide (NO) and adenosine, two putative mediators. Reactive hyperemia (30-s occlusion) was measured in open-chest dogs before and during 4-AP treatment [intracoronary (ic), plasma concentration 0.3 mM]. 4-AP reduced base

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Jiang, Qiu-Xing, and Gaya Yadav. "The mechanisms of chromogranin B-regulated Cl− homeostasis." Biochemical Society Transactions 50, no. 6 (2022): 1659–72. http://dx.doi.org/10.1042/bst20220435.

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Chloride is the most abundant inorganic anions in almost all cells and in human circulation systems. Its homeostasis is therefore important for systems physiology and normal cellular activities. This topic has been extensively studied with chloride loaders and extruders expressed in both cell surfaces and intracellular membranes. With the newly discovered, large-conductance, highly selective Cl− channel formed by membrane-bound chromogranin B (CHGB), which differs from all other known anion channels of conventional transmembrane topology, and is distributed in plasma membranes, endomembrane sy

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McDaniel, Sharon S., Oleksandr Platoshyn, Ying Yu, et al. "Anorexic effect of K+ channel blockade in mesenteric arterial smooth muscle and intestinal epithelial cells." Journal of Applied Physiology 91, no. 5 (2001): 2322–33. http://dx.doi.org/10.1152/jappl.2001.91.5.2322.

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Activity of voltage-gated K+ (Kv) channels controls membrane potential ( E m). Membrane depolarization due to blockade of K+ channels in mesenteric artery smooth muscle cells (MASMC) should increase cytoplasmic free Ca2+ concentration ([Ca2+]cyt) and cause vasoconstriction, which may subsequently reduce the mesenteric blood flow and inhibit the transportation of absorbed nutrients to the liver and adipose tissue. In this study, we characterized and compared the electrophysiological properties and molecular identities of Kv channels and examined the role of Kv channel function in regulating E m

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Gan, Wei, and Bo Huang. "Exploring Data Integrity of Dual-Channel Supply Chain Using Blockchain Technology." Computational Intelligence and Neuroscience 2022 (May 18, 2022): 1–13. http://dx.doi.org/10.1155/2022/3838282.

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The study intends to solve the problems of complex product circulation caused by information asymmetry and the untimely communication of production and sales information in the process of product sales to reduce the cost in the process of product circulation. Based on blockchain technology, the data integrity of the dual-channel supply chain is studied. First, the data of the supply chain conduct coordinated management to achieve the integrity of the supply chain data. Then, under the background that both retailers and suppliers are risk-neutral individuals, the benchmark model of the dual-cha

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Yung, Kaung-Ti. "A Birdcage Model for the Chinese Meridian System Part VI: Meridians as the Primary Regulatory System." American Journal of Chinese Medicine 33, no. 05 (2005): 759–66. http://dx.doi.org/10.1142/s0192415x05003302.

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It is imperative to define the fundamental concepts of Qi, channels, and the meridian system of Chinese medicine in terms of scientific terminology before any meaningful and mutually beneficial dialog can begin between Chinese and Western medicine. In the Chinese theory, the meridian system as a whole is the system of the body. We propose the existence of a meridian regulatory system that governs interactions between and adjusts functions of internal organs, connects them to the body surface through a network of pathways (channels) and displays their status on the skin. The meridian systems is

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