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Journal articles on the topic 'Clastogenia'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 February 2022

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1

Heindorff, K., R. Rieger, A. Michaelis, and S. Takehisa. "Clastogenic adaptation triggered by S-phase-independent clastogens in Vicia faba." Mutation Research Letters 190, no. 2 (1987): 131–35. http://dx.doi.org/10.1016/0165-7992(87)90044-3.

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2

Bryce, Steven M., Stephen D. Dertinger та Jeffrey C. Bemis. "Kinetics of γH2AX and phospho-histone H3 following pulse treatment of TK6 cells provides insights into clastogenic activity". Mutagenesis 36, № 3 (2021): 255–64. http://dx.doi.org/10.1093/mutage/geab014.

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Abstract The desire for in vitro genotoxicity assays to provide higher information content, especially regarding chemicals’ predominant genotoxic mode of action, has led to the development of a novel multiplexed assay available under the trade name MultiFlow®. We report here on an experimental design variation that provides further insight into clastogens’ genotoxic activity. First, the standard MultiFlow DNA Damage Assay—p53, γ H2AX, phospho-histone H3 was used with human TK6 lymphoblastoid cells that were exposed for 24 continuous hours to each of 50 reference clastogens. This initial analys

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3

Dokal, I., J. Bungey, P. Williamson, D. Oscier, J. Hows, and L. Luzzatto. "Dyskeratosis congenita fibroblasts are abnormal and have unbalanced chromosomal rearrangements." Blood 80, no. 12 (1992): 3090–96. http://dx.doi.org/10.1182/blood.v80.12.3090.bloodjournal80123090.

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Dyskeratosis congenita (DC) is a rare inherited disorder characterized by bone marrow failure, dystrophic changes in the skin and mucous membranes, and a predisposition to malignancy. The DC locus has been mapped to Xq28. The primary defect responsible for this disease remains unknown. We have studied four patients with this disease, three from one family and one from another. In all four patients, primary skin fibroblast cultures were abnormal both in morphology (polygonal cell shape, ballooning, and dendritic-like projections) and in growth rate (doubling time about twice normal). Fibroblast

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4

Grisolia, Cesar Koppe, and Célia Maria Torres Cordeiro. "Variability in micronucleus induction with different mutagens applied to several species of fish." Genetics and Molecular Biology 23, no. 1 (2000): 235–39. http://dx.doi.org/10.1590/s1415-47572000000100041.

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Fish are often used for screening genotoxicity of water. For such programs, a knowledge of the sensitivity to clastogens, spontaneous micronucleus frequency and cell cycle kinetics of the target tissue is necessary. To investigate the pattern of inter-specific sensitivity to micronucleus induction three species of fish, Tilapia rendalli, Oreochromis niloticus and Cyprinus carpio, were exposed to the clastogens bleomycin (BLM), cyclophosphamide (CP), 5-fluorouracil (5-FU), and mitomycin C (MMC). The binucleate/mononucleate ratio in peripheral erythrocytes exposed to cytochalasin B was also used

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5

Hamada, K., T. Kumazaki, K. Mizuno, and K. Yokoro. "A small nuclear RNA, U5, can transform cells in vitro." Molecular and Cellular Biology 9, no. 10 (1989): 4345–56. http://dx.doi.org/10.1128/mcb.9.10.4345.

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Low-molecular-weight RNA exhibiting transforming potential was identified in chemically induced lymphoma cells by the transformation of mink lung cells after transfection. The RNA was sequenced by the direct chemical method and was shown to be a small nuclear RNA, U5. The transforming potential of the RNA was further studied in quantitative transformation assays using 3Y1, a rat fibroblastic cell line. Transformed foci appeared with a latency of 3 to 4 weeks after transfection. U5-transformed 3Y1 cells frequently carried an amplified c-myc oncogene. In addition, U5 induced chromosome aberratio

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6

Hamada, K., T. Kumazaki, K. Mizuno, and K. Yokoro. "A small nuclear RNA, U5, can transform cells in vitro." Molecular and Cellular Biology 9, no. 10 (1989): 4345–56. http://dx.doi.org/10.1128/mcb.9.10.4345-4356.1989.

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Low-molecular-weight RNA exhibiting transforming potential was identified in chemically induced lymphoma cells by the transformation of mink lung cells after transfection. The RNA was sequenced by the direct chemical method and was shown to be a small nuclear RNA, U5. The transforming potential of the RNA was further studied in quantitative transformation assays using 3Y1, a rat fibroblastic cell line. Transformed foci appeared with a latency of 3 to 4 weeks after transfection. U5-transformed 3Y1 cells frequently carried an amplified c-myc oncogene. In addition, U5 induced chromosome aberratio

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7

Dokal, I., J. Bungey, P. Williamson, D. Oscier, J. Hows, and L. Luzzatto. "Dyskeratosis congenita fibroblasts are abnormal and have unbalanced chromosomal rearrangements." Blood 80, no. 12 (1992): 3090–96. http://dx.doi.org/10.1182/blood.v80.12.3090.3090.

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Abstract Dyskeratosis congenita (DC) is a rare inherited disorder characterized by bone marrow failure, dystrophic changes in the skin and mucous membranes, and a predisposition to malignancy. The DC locus has been mapped to Xq28. The primary defect responsible for this disease remains unknown. We have studied four patients with this disease, three from one family and one from another. In all four patients, primary skin fibroblast cultures were abnormal both in morphology (polygonal cell shape, ballooning, and dendritic-like projections) and in growth rate (doubling time about twice normal). F

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8

Mohanvel, Sucharitha Kannappan, Satish Kumar Rajasekharan, Trishna Kandhari, Balaji Prasanna Kumar Gopal Doss, and Yuvarani Thambidurai. "COW URINE DISTILLATE AS A BIOENHANCER FOR ANTIMICROBIAL & ANTIPROLIFERATIVE ACTIVITY AND REDISTILLED COW URINE DISTILLATE AS AN ANTICLASTOGEN AGENT." Asian Journal of Pharmaceutical and Clinical Research 10, no. 10 (2017): 273. http://dx.doi.org/10.22159/ajpcr.2017.v10i10.18879.

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Objective: The objective of this study was to prove that cow urine distillate (CUD) is a bioenhancer for antimicrobial activity and antiproliferative activity, redistilled CUD (RCUD) as an anticlastogen agent.Methods: The antimicrobial activity of rifampicin with CUD at different concentrations was determined against pathogenic Escherichia coli by well puncture method. The Penicillin and ciprofloxacin in combination with CUD at different/increasing concentrations against pathogenic E. coli culture were also determined by disc diffusion method. Sulforaphane (ACA) as an anticancer agent was extr

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9

van Beerendonk, G. J. M., S. D. Nelson, and J. H. N. Meerman. "Metabolism and Genotoxicity of the Halogenated Alkyl Compound Tris(2,3-Dibromopropyl)phosphate." Human & Experimental Toxicology 13, no. 12 (1994): 861–65. http://dx.doi.org/10.1177/096032719401301208.

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1 The genotoxicity of the flame retardant tris(2,3-dibromopropyl)phosphate (Tris-BP) was studied in vivo. Results showed that Tris-BP was highly clasfogenic, but it could only initiate a low number of preneoplastic foci in the rat liver in vivo. In Drosophila, Tris-BP could be classified as a cross-linking agent, because it was more clastogenic than mutagenic. The use of completely deuterated Tris-BP as a metabolic probe revealed that cytochrome P450 and most likely the formation of 2-bromoacrolein (2BA) from Tris-BP is important for the observed genotoxic effects. 2 In contrast to the high mu

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10

Huang, ZH, N. Li, KF Rao, et al. "Development of a data-processing method based on Bayesian k-means clustering to discriminate aneugens and clastogens in a high-content micronucleus assay." Human & Experimental Toxicology 37, no. 3 (2017): 285–94. http://dx.doi.org/10.1177/0960327117695635.

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Genotoxicants can be identified as aneugens and clastogens through a micronucleus (MN) assay. The current high-content screening-based MN assays usually discriminate an aneugen from a clastogen based on only one parameter, such as the MN size, intensity, or morphology, which yields low accuracies (70–84%) because each of these parameters may contribute to the results. Therefore, the development of an algorithm that can synthesize high-dimensionality data to attain comparative results is important. To improve the automation and accuracy of detection using the current parameter-based mode of act

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11

Heindorff, K., R. Rieger, I. Schubert, A. Michaelis, and O. Aurich. "Clastogenic adaptation of plant cells — reduction of the yield of clastogen-induced chromatid aberrations by various pretreatment procedures." Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 181, no. 1 (1987): 157–71. http://dx.doi.org/10.1016/0027-5107(87)90296-x.

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12

Ueda, T., M. Hayashi, Y. Ohtsuka, T. Nakamura, J. Kobayashi, and T. Sofuni. "A Preliminary Study of the Micronucleus Test by Acridine Orange Fluorescent Staining Compared with Chromosomal Aberration Test Using Fish Erythropoietic and Embryonic Cells." Water Science and Technology 25, no. 11 (1992): 235–40. http://dx.doi.org/10.2166/wst.1992.0297.

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The micronucleus test using fish peripheral blood has been introduced to assess the contamination of water with some mutagenic chemicals. The applicability of the micronucleus test erythrocytes combining acridine orange (AO) fluorescent staining to fish was evaluated as compared with the chromosomal aberration test method. Peripheral blood cells were smeared on glass slides, fixed with methanol, and stained with AO. AO fluorescence microscopy could differentiate between young and mature erythrocytes, thus only young erythrocytes could be observed. The sensitivity to detect the clastogenic effe

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13

Rieger, Rigomar, Arnd Michaelis, and Shin Takehisa. "‘Clastogenic cross-adaptation’ is dependent on the clastogens used for induction of chromatid aberrations in Vicia faba root-tip meristems." Mutation Research Letters 144, no. 3 (1985): 171–75. http://dx.doi.org/10.1016/0165-7992(85)90135-6.

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14

Angeli, J. Pf, L. R. Ribeiro, M. F. Bellini, and M. S. Mantovani. "Anti-clastogenic effect of b-glucan extracted from barley towards chemically induced DNA damage in rodent cells." Human & Experimental Toxicology 25, no. 6 (2006): 319–24. http://dx.doi.org/10.1191/0960327106ht631oa.

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b-Glucan (BG) was tested in vitro to determine its potential clastogenic and/or anti-clastogenic activity, and attempts were made to elucidate its possible mechanism of action by using combinations with an inhibitor of DNA polymerase. The study was carried out on cells deficient (CHO-k1) and cells proficient (HTC) in phases I and II enzymes, and the DNA damage was assessed by the chromosomal aberration assay. BG did not show a clastogenic effect, but was anti-clastogenic in both cell lines used, and at all concentrations tested (2.5, 5 and 10 mg/mL) in combination with damage inducing agents (

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15

Anwar, Wagida A. "Praziquantel (antischistosomal drug): is it clastogenic, co-clastogenic or anticlastogenic?" Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 305, no. 2 (1994): 165–73. http://dx.doi.org/10.1016/0027-5107(94)90236-4.

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16

Kushwah, Khushboo, Ravendra Singh Chauhan, R. K. Sarbhoy, and Harshal Kumar. "Chromosomal Aberrations Induced by Carbaryl in Root Meristem Cells of Pisum Sativum L." Biosciences, Biotechnology Research Asia 14, no. 3 (2017): 985–87. http://dx.doi.org/10.13005/bbra/2532.

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ABSTRACT: Carbaryl, which is also known as sevin, induced mitostatic and turbagenic leading to clastogenic effects in the root meristem cells of Pisum sativum. The study was conducted at Department of Botany, Agra College, Agra. Seeds of uniform size of Pisum sativum were germinated on moist filter paper in petriplates. 1to 2 mm root tips were cut and treated with different concentrations (0.1, 0.2, 0.3,0.5%) of carbaryl prepared in distilled water for varying duration (3 to 9 hrs.) of time. It has mitodepressive and mitostatic effects on somatic cell division. These effects are directly propo

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17

Shadab, Ghulam GHA. "The dual clastogenic and anti-clastogenic properties of quercetin is dose dependent." Frontiers in Bioscience 9, no. 1 (2017): 139–53. http://dx.doi.org/10.2741/s478.

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18

Topashka-Ancheva, Margarita, Rilka Taskova, Nedjalka Handjieva, Bozhanka Mikhova, and Helmut Duddeck. "Clastogenic Effect of Carthamus lanatus L. (Asteraceae)." Zeitschrift für Naturforschung C 58, no. 11-12 (2003): 833–36. http://dx.doi.org/10.1515/znc-2003-11-1216.

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Abstract The clastogenic effect of total dichloromethane, methanol and water extracts, four bioactive fractions and three individual constituents from Carthamus lanatus aerial parts were evaluated in mice by bone marrow chromosome aberration assay with mitomycin C as positive control. Significant differences in the percentage of aberrant mitosis of the extracts were observed. The dichloromethane extract exhibited a considerable clastogenic effect and the water extract a negligible one. Different types of chromosome aberrations and time-dependant effects for the active fractions and individual

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19

Au, William W., Wagida Anwar, Moreno Paolini, Sadagopa Ramanujam, and Giorgio Cantelli-Forti. "Mechanism of clastogenic and co-clastogenic activity of cremophore with benzene hi mice." Carcinogenesis 12, no. 1 (1991): 53–57. http://dx.doi.org/10.1093/carcin/12.1.53.

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20

Filipe, P., I. Emerit, A. Alaoui Youssefi, et al. "Oxyradical-mediated Clastogenic Plasma Factors in Psoriasis: Increase in Clastogenic Activity after PUVA." Photochemistry and Photobiology 66, no. 4 (1997): 497–501. http://dx.doi.org/10.1111/j.1751-1097.1997.tb03179.x.

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21

Rezende, Manuela da Rocha Matos, Vivianne de Souza Velozo-Sá, Cesar Augusto Sam Tiago Vilanova-Costa, and Elisangela Silveira-Lacerda. "Cytotoxic, clastogenic and genotoxic effects of cis-tetraammine(oxalato)ruthenium(III) dithionate on human peripheral blood lymphocytes." Acta Scientiarum. Biological Sciences 42 (May 19, 2020): e50517. http://dx.doi.org/10.4025/actascibiolsci.v42i1.50517.

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There is a concern about stablishing the clinical risk of drugs used for cancer treatment. In this study, the cytotoxic, clastogenic and genotoxic properties of cis-tetraammine(oxalato)ruthenium(III) dithionite - cis-[Ru(C2O4)(NH3)4]2(S2O6), were evaluated in vitro in human lymphocytes. The mitotic index (MI), chromosomal aberrations (CA) and DNA damage by comet assay were also analyzed. The MTT test revealed that the ruthenium compound showed a slight cytotoxic effect at the highest concentration tested. The IC50 value for the compound after 24 hours of exposure was 185.4 µM. The MI values of

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22

Seoane, A. I., and F. N. Dulout. "Contribution to the validation of the anaphase-telophase test: aneugenic and clastogenic effects of cadmium sulfate, potassium dichromate and nickel chloride in Chinese hamster ovary cells." Genetics and Molecular Biology 22, no. 4 (1999): 551–55. http://dx.doi.org/10.1590/s1415-47571999000400015.

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There is increasing evidence that aneuploidy during mitosis may be a factor in the etiology of somatic malignancy. The analysis of alterations in anaphase-telophase of mitosis is a useful test for evaluating the aneuploidogenic and clastogenic ability of chemicals. Several metals have been found to be carcinogenic to humans and animals. However, the underlying mechanisms remain unclear. In the present study the aneugenic and clastogenic abilities of cadmium sulfate, potassium dichromate and nickel chloride were analyzed using the anaphase-telophase test. Chinese hamster ovary (CHO) cells cultu

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23

Durnev, Andrey D., Natalia O. Daugel-Dauge, Alii K. Zhanataev, Anastasia S. Lapitskaya, and Sergey B. Seredenin. "Comutagenic effects of valocordin." Ecological genetics 10, no. 3 (2012): 53–58. http://dx.doi.org/10.17816/ecogen10353-58.

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The chromosome aberration test in bone marrow cells of mice was used to study the influence of valocordin on spontaneous and induced clastogenesis. Valocordin showed no inherent clastogenic activity. In experiments with pretreatment and with single or repeated combined administration , valocordin in doses of 0.03, 0.3 and 3 ml/kg significantly (47–133 %) enhanced the clastogenic activity of cyclophosphamide. There was no effect of valocordin on the cytogenetic activity of dioxidine, a mutagen with a pro-oxidative mode of action. Possible mechanisms of comutagenic activity of valocordin are dis

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24

Konishi, Taiji, Kazufumi Naitou, Shin-Ichi Kadowaki, Yoshinori Takahara, and Koji Yamamoto. "Anti-clastogenic ingredients inCassia nomameextract." BioFactors 22, no. 1-4 (2004): 99–102. http://dx.doi.org/10.1002/biof.5520220119.

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25

Musk, S. R. R., and I. T. Johnson. "The clastogenic effects of isothiocyanates." Mutation Research/Genetic Toxicology 300, no. 2 (1993): 111–17. http://dx.doi.org/10.1016/0165-1218(93)90128-z.

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26

Adler, I. D., and A. El-Tarras. "Clastogenic effects of cis-diamminedichloroplatinum." Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 211, no. 1 (1989): 131–37. http://dx.doi.org/10.1016/0027-5107(89)90113-9.

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27

Birnboim, H. C. "DNA clastogenic activity of diethylstilbestrol." Biochemical Pharmacology 34, no. 18 (1985): 3251–57. http://dx.doi.org/10.1016/0006-2952(85)90342-9.

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28

Slameňová, Darina, Ivan Chalupa, Alena Gábelová, Eva Bozsakyová, Eva Horváthová, and Milan Blaško. "Toxicity, Clastogenicity and Genotoxicity of Theophylline and Pentoxifylline in Mammalian Cells Cultured In Vitro." Alternatives to Laboratory Animals 23, no. 4 (1995): 504–12. http://dx.doi.org/10.1177/026119299502300414.

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— As part of a developmental study on theophylline and pentoxifylline, these drugs were tested for possible cytotoxic, mutagenic and clastogenic effects on V79 hamster cells and human lymphocytes cultured in vitro. After the short-term treatment of V79 cells with theophylline and pentoxifylline, the cells were relatively resistant to the toxic effects of these methylxanthines. Generally, only high concentrations of theophylline or pentoxifylline had toxic effects on exposed V79 cells. Short-term treatment of V79 cells with theophylline or pentoxifylline did not induce 6-thioguanine resistant m

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29

Burim, Regislaine V., Renata Canalle, João L. Callegari Lopes, and Catarina S. Takahashi. "Genotoxic action of the sesquiterpene lactone glaucolide B on mammalian cells in vitro and in vivo." Genetics and Molecular Biology 22, no. 3 (1999): 401–6. http://dx.doi.org/10.1590/s1415-47571999000300020.

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Glaucolide B is a sesquiterpene lactone isolated from Vernonia eremophila Mart. (Vernonieae, Asteraceae) and has schistosomicidal, antimicrobial and analgesic activities. This study examined the cytotoxic and clastogenic activities of glaucolide B in human cultured lymphocytes and in bone marrow cells from BALB/c mice. The mitotic index (MI) and chromosomal aberrations were analyzed in both of the above systems, whereas sister chromatid exchanges (SCE) and the proliferation index (PI) were determined only in vitro. In human cultured lymphocytes, glaucolide B concentrations greater than 15 µg/m

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30

Antunes, Lusânia M. Greggi, Joana D. C. Darin, and Maria de Lourdes P. Bianchi. "Anticlastogenic effect of vitamin C on cisplatin in vivo." Genetics and Molecular Biology 22, no. 3 (1999): 415–17. http://dx.doi.org/10.1590/s1415-47571999000300022.

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The ability of vitamin C (VC) to protect against the clastogenic action of the chemotherapeutic agent cisplatin (DDP, cis-diamminedichloroplatinun II) in rat bone marrow cells was evaluated. DDP was administered to Wistar rats either alone or after treatment with VC. The rats were treated with VC (50, 100 or 200 mg/kg body weight) by gavage 10 min before the administration of DDP (5 mg/kg body weight, ip) and then sacrificed 24 h after treatment. VC significantly reduced (by about 70%) the clastogenicity of DDP in rat bone marrow cells. The antioxidant action of VC presumably modulates the cla

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31

Yordi, Estela Guardado, Enrique Molina Pérez, Maria Joao Matos, and Eugenio Uriarte Villares. "Structural Alerts for Predicting Clastogenic Activity of Pro-oxidant Flavonoid Compounds." Journal of Biomolecular Screening 17, no. 2 (2011): 216–24. http://dx.doi.org/10.1177/1087057111421623.

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Flavonoids have been reported to exert multiple biological effects that include acting as pro-oxidants at very high doses. The authors determined a structural alert to identify the clastogenic activity of a series of flavonoids with pro-oxidant activity. The methodology was based on a quantitative structure–activity relationship (QSAR) study. Specifically, the authors developed a virtual screening method for a clastogenic model using the topological substructural molecular design (TOPS-MODE) approach. It represents a useful platform for the automatic generation of structural alerts, based on t

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32

Barajas Torres, Reyna Lucía, Martín Daniel Domínguez Cruz, César Borjas Gutiérrez, María de Lourdes Ramírez Dueñas, María Teresa Magaña Torres, and Juan Ramón González García. "1,2:3,4-Diepoxybutane Induces Multipolar Mitosis in Cultured Human Lymphocytes." Cytogenetic and Genome Research 148, no. 2-3 (2016): 179–84. http://dx.doi.org/10.1159/000445858.

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1,3-Butadiene, a colorless gas regularly used in the production of plastics, thermoplastic resins, and styrene-butadiene rubber, poses an increased leukemia mortality risk to workers in this field. 1,3-Butadiene is also produced by incomplete combustion of motor fuels or by tobacco smoking. It is absorbed principally through the respiratory system and metabolized by several enzymes rendering 1,2:3,4-diepoxybutane (DEB), which has the highest genotoxic potency of all metabolites of 1,3-butadiene. DEB is considered a carcinogen mainly due to its high potential as clastogen, which induces structu

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33

Maistro, Edson, Diego Fernandes, Fernanda Pereira, and Sergio Andrade. "Lapachol Induces Clastogenic Effects in Rats." Planta Medica 76, no. 09 (2010): 858–62. http://dx.doi.org/10.1055/s-0029-1240816.

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34

NORDENSON, I., G. BECKMAN, L. BECKMAN, L. ROSENHALL, and N. STJERNBERG. "Is exposure to sulphur dioxide clastogenic?" Hereditas 93, no. 1 (2009): 161–64. http://dx.doi.org/10.1111/j.1601-5223.1980.tb01056.x.

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35

Lindholm, Carita, Anna Acheva, and Sisko Salomaa. "Clastogenic plasma factors: a short overview." Radiation and Environmental Biophysics 49, no. 2 (2009): 133–38. http://dx.doi.org/10.1007/s00411-009-0259-3.

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36

Balansky, Roumen, Penka Blagoeva, and Zwetana Mircheva. "Clastogenic activity of urethane in mice." Mutation Research Letters 281, no. 2 (1992): 99–103. http://dx.doi.org/10.1016/0165-7992(92)90043-h.

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37

Emerit, I., S. H. Khan, and H. Esterbauer. "Hydroxynonenal, a component of clastogenic factors?" Free Radical Biology and Medicine 10, no. 6 (1991): 371–77. http://dx.doi.org/10.1016/0891-5849(91)90045-5.

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38

Almeida, Igor Vivian de, Giovana Domingues, Lilian Capelari Soares, Elisângela Düsman, and Veronica Elisa Pimenta Vicentini. "Evaluation of cytotoxicity and mutagenicity of the benzodiazepine flunitrazepam in vitro and in vivo." Brazilian Journal of Pharmaceutical Sciences 50, no. 2 (2014): 251–56. http://dx.doi.org/10.1590/s1984-82502014000200003.

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Flunitrazepam (FNZ) is a sedative benzodiazepine prescribed for the short-term treatment of insomnia. However, there are concerns regarding possible carcinogenic or genotoxic effects of this medicine. Thus, the aim of this study was to evaluate the cytotoxic, clastogenic and aneugenic effects of FNZ in hepatoma cells from Rattus norvegicus (HTC) in vitro and in bone marrow cells of Wistar rats in vivo. These effects were examined in vitro following treatment with 0.2, 1.0, 5.0 or 10 μg/mL FNZ using a micronucleus test with a cytokinesis block or in vivo using a chromosomal aberration test foll

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39

Anwar, Sirajudheen, Siddique Akber Ansari, Abdulwahab Alamri, et al. "Clastogenic, anti-clastogenic profile and safety assessment of Camel urine towards the development of new drug target." Food and Chemical Toxicology 151 (May 2021): 112131. http://dx.doi.org/10.1016/j.fct.2021.112131.

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40

Lloyd, D. C., and J. E. Moquet. "The Clastogenic Effect of Irradiated Human Plasma." International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 47, no. 4 (1985): 433–44. http://dx.doi.org/10.3109/rab.47.4.433.

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41

Kito, Hideaki, Hisamitsu Nagase, Takahiko Sato, Takamitsu Kurimoto, Masahiko Satoh, and Chiharu Tohyama. "Clastogenic effect of mitomycin in metallothioneinnull mice." Journal of Inorganic Biochemistry 67, no. 1-4 (1997): 153. http://dx.doi.org/10.1016/s0162-0134(97)80031-1.

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42

&NA;. "Clastogenic effects of deferiprone to be studied." Inpharma Weekly &NA;, no. 1210 (1999): 19. http://dx.doi.org/10.2165/00128413-199912100-00045.

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43

Abba, M., J. C. De Luca, G. Mattioli, E. Zaccardi, and F. N. Dulout. "Clastogenic effect of copper deficiency in cattle." Mutation Research/Genetic Toxicology and Environmental Mutagenesis 466, no. 1 (2000): 51–55. http://dx.doi.org/10.1016/s1383-5718(00)00002-4.

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&NA;. "Clastogenic effects of deferiprone to be studied." Reactions Weekly &NA;, no. 774 (1999): 2. http://dx.doi.org/10.2165/00128415-199907740-00002.

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Abraham, Susan, Radhamoni G., Annie T. John, and Saju Abraham. "Clastogenic activity of quinoline, isoquinoline and pyridine." CYTOLOGIA 55, no. 4 (1990): 659–62. http://dx.doi.org/10.1508/cytologia.55.659.

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Mukhopadhyay, Madhumita J., and Anita Mukherjee. "Clastogenic effect of ginger rhizome in mice." Phytotherapy Research 14, no. 7 (2000): 555–57. http://dx.doi.org/10.1002/1099-1573(200011)14:7<555::aid-ptr659>3.0.co;2-j.

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Kitamura, Mari, Koichi Kuroda, Yoko Endo, and Ginji Endo. "Cysteine enhances clastogenic activity of dimethylarsinic acid." Applied Organometallic Chemistry 16, no. 7 (2002): 391–96. http://dx.doi.org/10.1002/aoc.310.

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Lloyd, D. C., and J. E. Moquet. "The Clastogenic Effect of Irradiated Human Plasma." International Journal of Radiation Biology 47, no. 4 (1985): 433–44. http://dx.doi.org/10.1080/713860600.

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Tates, A. D., N. De Vogel, and A. H. M. Rotteveel. "Clastogenic effects of genotoxins in rat spermatocytes." Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 181, no. 2 (1987): 352–53. http://dx.doi.org/10.1016/0027-5107(87)90204-1.

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EMERIT, I., A. LEVY, and J. CAMUS. "Monocyte-derived clastogenic factor in rheumatoid arthritis." Free Radical Biology and Medicine 6, no. 3 (1989): 245–50. http://dx.doi.org/10.1016/0891-5849(89)90051-8.

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