Log in

Relevant bibliographies by topics / Clavulanate acid

Contents

Journal articles
Dissertations / Theses

Academic literature on the topic 'Clavulanate acid'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Clavulanate acid.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Clavulanate acid"

1

Drozdov, V. N., D. D. Ermakova, S. Yu Serebrova, et al. "Therapeutic potential of combination antimicrobial drug amoxycillin/clavulanate in children." Meditsinskiy sovet = Medical Council, no. 10 (July 29, 2020): 144–50. http://dx.doi.org/10.21518/2079-701x-2020-10-144-150.

Full text

Abstract:

Combination of amoxicillin/clavulanate firstly occurred on a pharmacological market in 1977 and it is still has been used successfully for treatment of infections in children and adults. Clavulanic acid provides an opportunity to fight microorganisms that produce specific enzymes – beta-lactamases. Despite the global antibiotic resistance problem, amoxicillin/clavulanate is still active against different infections in children. The level of susceptibility to amoxicillin/clavulanate of St. pneumonia is high for a period of 40 years. Based on the multicenter study of the antimicrobial resistance

APA, Harvard, Vancouver, ISO, and other styles

2

Severin, A., E. Severina, and A. Tomasz. "Abnormal physiological properties and altered cell wall composition in Streptococcus pneumoniae grown in the presence of clavulanic acid." Antimicrobial Agents and Chemotherapy 41, no. 3 (1997): 504–10. http://dx.doi.org/10.1128/aac.41.3.504.

Full text

Abstract:

Subinhibitory concentrations of clavulanate caused premature induction of stationary-phase autolysis, sensitization to lysozyme, and reductions in the MICs of deoxycholate and penicillin for Streptococcus pneumoniae. In the range of clavulanate concentrations producing these effects, this beta-lactam compound was selectively bound to PBP 3. Cell walls isolated from pneumococci grown in the presence of clavulanate showed increased sensitivity to the hydrolytic action of purified pneumococcal autolysin in vitro. High-performance liquid chromatography analysis of the peptidoglycan isolated from t

APA, Harvard, Vancouver, ISO, and other styles

3

Berry, Valerie, Jennifer Hoover, Christine Singley, and Gary Woodnutt. "Comparative Bacteriological Efficacy of Pharmacokinetically Enhanced Amoxicillin-Clavulanate against Streptococcus pneumoniae with Elevated Amoxicillin MICs and Haemophilus influenzae." Antimicrobial Agents and Chemotherapy 49, no. 3 (2005): 908–15. http://dx.doi.org/10.1128/aac.49.3.908-915.2005.

Full text

Abstract:

ABSTRACT A new pharmacokinetically enhanced formulation of amoxicillin-clavulanate (2,000 mg of amoxicillin/125 mg of clavulanate twice a day; ratio 16:1) has been designed, with sustained-release technology, to allow coverage of bacterial strains with amoxicillin-clavulanic acid MICs of at least 4/2 μg/ml. The bacteriological efficacy of amoxicillin-clavulanate, 2,000/125 mg twice a day, ratio 16:1, was compared in a rat model of respiratory tract infection versus four other amoxicillin-clavulanate formulations: 8:1 three times a day (1,000/125 mg), 7:1 three times a day (875/125 mg), 7:1 twi

APA, Harvard, Vancouver, ISO, and other styles

4

Jerzsele, Ákos, and Gábor Nagy. "The stability of amoxicillin trihydrate and potassium clavulanate combination in aqueous solutions." Acta Veterinaria Hungarica 57, no. 4 (2009): 485–93. http://dx.doi.org/10.1556/avet.57.2009.4.3.

Full text

Abstract:

The effect of various environmental factors on the stability of aqueous solutions of amoxicillin-clavulanic acid combination in a veterinary water-soluble powder product was investigated. In the swine industry, the combination is administered via the drinking water, where both substances are quickly decomposed depending on several environmental factors. The degradation rate of the substances was determined in solutions of different water hardness levels (German hardness of 2, 6 and 10) and pH values (3.0, 7.0 and 10.0), and in troughs made of different materials (metal or plastic). Increasing

APA, Harvard, Vancouver, ISO, and other styles

5

Fricke, G., M. Doerck, D. Hafner, R. Horton, and M. Kresken. "The pharmacokinetics of ticarcillin/clavulanate acid in neonates." Journal of Antimicrobial Chemotherapy 24, suppl B (1989): 111–20. http://dx.doi.org/10.1093/jac/24.suppl_b.111.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Manageiro, Vera, Eugénia Ferreira, Antony Cougnoux, Luís Albuquerque, Manuela Caniça та Richard Bonnet. "Characterization of the Inhibitor-Resistant SHV β-Lactamase SHV-107 in a Clinical Klebsiella pneumoniae Strain Coproducing GES-7 Enzyme". Antimicrobial Agents and Chemotherapy 56, № 2 (2011): 1042–46. http://dx.doi.org/10.1128/aac.01444-10.

Full text

Abstract:

ABSTRACTThe clinicalKlebsiella pneumoniaeINSRA6884 strain exhibited nonsusceptibility to all penicillins tested (MICs of 64 to >2,048 μg/ml). The MICs of penicillins were weakly reduced by clavulanate (from 2,048 to 512 μg/ml), and tazobactam restored piperacillin susceptibility. Molecular characterization identified the genesblaGES-7and a new β-lactamase gene,blaSHV-107, which encoded an enzyme that differed from SHV-1 by the amino acid substitutions Leu35Gln and Thr235Ala. The SHV-107-producingEscherichia colistrain exhibited only a β-lactam resistance phenotype with respect to amoxicilli

APA, Harvard, Vancouver, ISO, and other styles

7

Lee, Sangyoung, Da Hyun Kim, Sabin Shin, et al. "Development and Validation of Bioanalytical LC–MS/MS Method for Pharmacokinetic Assessment of Amoxicillin and Clavulanate in Human Plasma." Pharmaceuticals 18, no. 7 (2025): 998. https://doi.org/10.3390/ph18070998.

Full text

Abstract:

Background/Objectives: We developed and validated a robust and simple LC–MS/MS method for the simultaneous quantification of amoxicillin and clavulanate in human plasma relative to previously reported methods. Methods: Amoxicillin; clavulanate; and an internal standard, 4-hydroxytolbutamide, in human K2-EDTA plasma, were deproteinized with acetonitrile and then subjected to back-extraction using distilled water–dichloromethane. Separation was performed on a Poroshell 120 EC-C18 column with a mobile-phase gradient comprising 0.1% aqueous formic acid and acetonitrile at a flow rate of 0.5 mL/min

APA, Harvard, Vancouver, ISO, and other styles

8

Simpson, I., J. Durodie, S. Knott, B. Shea, J. Wilson, and K. Machka. "Effects of Following National Committee for Clinical Laboratory Standards and Deutsche Industrie Norm-Medizinische Mikrobiologie Guidelines, Country of Isolate Origin, and Site of Infection on Susceptibility of Escherichia coli to Amoxicillin-Clavulanate (Augmentin)." Journal of Clinical Microbiology 36, no. 5 (1998): 1361–65. http://dx.doi.org/10.1128/jcm.36.5.1361-1365.1998.

Full text

Abstract:

Amoxicillin-clavulanate (Augmentin), as a combination of two active agents, poses extra challenges over single agents in establishing clinically relevant breakpoints for in vitro susceptibility tests. Hence, reported differences in amoxicillin-clavulanate percent susceptibilities among Escherichia coli isolates may reflect localized resistance problems and/or methodological differences in susceptibility testing and breakpoint criteria. The objectives of the present study were to determine the effects of (i) methodology, e.g., those of the National Committee for Clinical Laboratory Standards (N

APA, Harvard, Vancouver, ISO, and other styles

9

Jin, Xiaoqing, Guangxiang Cao, Xiaoxiao Zhang, Yuguo Chen, Liang Wang, and Chuanqing Zhong. "Studies on the formation and synthetic mechanism of related substance G in potassium clavulanate production." Brazilian Journal of Pharmaceutical Sciences 51, no. 1 (2015): 77–83. http://dx.doi.org/10.1590/s1984-82502015000100008.

Full text

Abstract:

The objective of this study was to investigate the formation and synthetic mechanism of related substance G in potassium clavulanate production. The impurity in the potassium clavulanate final product, with a retention time of 13.5 min, was confirmed as related substance G by high performance liquid chromatography-mass spectrometry/mass spectrometry. Related substance G analysis during the production of clavulanic acid showed that this impurity could be synthesized during fermentation, and the amount increased with the fermentation time. Studies on its synthetic mechanism showed that L-tyrosin

APA, Harvard, Vancouver, ISO, and other styles

10

Zade, S. S., Bhatpalliwar V.B, N. S. Mendhule, M. V. Murkhekar, R. S. Alaspure, and N. J. Durugkar. "Validation of RP-HPLC Method for Simultaneous Estimation of Cefixime Trihydrate and Clavulanate Potassium in Tablets." International Journal of Pharmaceutical Sciences and Nanotechnology 6, no. 2 (2013): 2033–39. http://dx.doi.org/10.37285/ijpsn.2013.6.2.4.

Full text

Abstract:

A simple, accurate, precise, rapid and economic HPLC method has been developed and validated for the simultaneous estimation of cefixime trihydrate and clavulanate potassium in tablet dosage forms. The chromatographic separation was achieved on a Hypersil C18 column (4.6 x 250 mm, 5 μm particle size). For HPLC method development, a mobile phase consisting of methanol: 30 mM potassium dihydrogen phosphate buffer pH 3.0 adjusted with orthophosphoric acid (30:70 v/v) was used at flow rate of 1.0 ml/min. The optimum wavelength selected was 278 nm. Under these chromatographic conditions, cefixime t

APA, Harvard, Vancouver, ISO, and other styles

More sources

Dissertations / Theses on the topic "Clavulanate acid"

1

Kalp, Matthew Douglas. "Raman Crystallographic Studies of Inhibitor Reactions in Class A β-Lactamases". Case Western Reserve University School of Graduate Studies / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=case1228504500.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

SOUZA, AMANDA de. "Avaliação citotóxica de Amoxilina e Clavulanato de Potássio em mexilhões Perna perna." reponame:Repositório Institucional do IPEN, 2016. http://repositorio.ipen.br:8080/xmlui/handle/123456789/26395.

Full text

Abstract:

Submitted by Claudinei Pracidelli (cpracide@ipen.br) on 2016-06-22T14:21:17Z No. of bitstreams: 0<br>Made available in DSpace on 2016-06-22T14:21:17Z (GMT). No. of bitstreams: 0<br>Dissertação (Mestrado em Tecnologia Nuclear)<br>IPEN/D<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!