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Dissertations / Theses on the topic 'CLDQ'

Author: Grafiati

Published: 3 June 2025

Last updated: 19 July 2025

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1

Mucci, Samantha [UNIFESP]. "Questionário para Avaliação de Qualidade de Vida em Portadores de Doença Hepática Crônica: Tradução e Validação do CLDQ – Chronic Liver Disease Questionnaire." Universidade Federal de São Paulo (UNIFESP), 2009. http://repositorio.unifesp.br/handle/11600/10002.

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Made available in DSpace on 2015-07-22T20:50:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-04-29<br>Nesse estudo objetivou-se realizar a tradução para o português e a adaptação cultural do instrumento Chronic Liver Disease Questionnaire (CLDQ) para uso no Brasil. O instrumento foi traduzido da versão original (Inglês) para a língua portuguesa pelos autores e, posteriormente, revisado e avaliado quanto ao grau de dificuldade das traduções e equivalência por tradutores bilíngües. O instrumento foi, então, aplicado em 20 pacientes com hepatopatia crônica selecionados aleatoriamente

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Sousa, Juliana Nunes. "Tradução e validação do questionário "Contact Lenses Dry Eye Questionnaire" (CLDEQ)." Master's thesis, Universidade da Beira Interior, 2012. http://hdl.handle.net/10400.6/1219.

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A nível mundial estima-se que a incidência de olho seco em usuários de lentes de contacto tende a aumentar. Deste modo, com a ausência de questionários traduzidos para o idioma português, e com a fraca correlação entre sinais e sintomas de olho seco associado com uso de lentes de contacto relatadas na comunidade científica, decidiu-se traduzir e validar cultural e linguisticamente para o idioma Português o questionário Contact Lenses Dry Eye Questionnaire (CLDEQ), desenvolvido por Carolyn G. Begley da University of Indiana em 2000. A metodologia adotada para a tradução e validação linguística

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3

Lyons, Robert Joseph 1963. "Determining distributed source waveforms in casual, lossy, dispersive, plane-wave (CLDP) materials." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/47722.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1998.<br>Includes bibliographical references (p. 284-291).<br>This thesis presents and employs novel mathematics for the inversion of linear, first-kind Fredholm integral equations (IEs) which have a time t dependent response signal, a space z dependent source waveform, and a kernel with time dependence (at each z) corresponding to the impulse response of a thickness z slab of causal, lossy, dispersive, homogeneous material through which planar disturbances propagate according to the w

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Schmidt, Bastian. "Veränderungen im LPS-Muster von E.coli Shigella durch cld pHS_-1tn2." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=980061172.

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Schmidt, Bastian. "Veränderungen im LPS-Muster von E.coli Shigella durch cld pHS-2." Doctoral thesis, Humboldt-Universität zu Berlin, Medizinische Fakultät - Universitätsklinikum Charité, 2006. http://dx.doi.org/10.18452/15463.

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Bei neun von vierzehn Serogruppen der Subspezies E. coli Flexneri (SF) konnte ein pHS-2-Plasmid nachgewiesen werden. Es besteht eine positive Korrelation zwischen pHS-2-positiven SF und dem Auftreten einer Reaktiven Arthritis, eine Komplikation der bakteriellen Ruhr. Verschiedene Autoren führen das gehäufte Auftreten der Reaktiven Arthritis bei pHS-2-positiven SF auf eine erhöhte Serumresistenz zurück, die den Bakterien durch das cld(pHS-2)-Gen vermittelt wird. Das cld(pHS-2)-Gen als längstes aller 18 "open reading frames" auf dem pHS-2-Plasmid kodiert für ein 35 kD großes Protein, das aufgrun

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Curley, A. E. "The role of inflammation in the evolution of chronic lung disease in the neonate." Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391115.

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Króner, Tomáš. "Mobilní přehrávač pro příjem a zpracování multimediálních dat." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2009. http://www.nusl.cz/ntk/nusl-218119.

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Master’s thesis deals with developing of multimedia application that allow play and receive multimedia files as audio and video. In thesis introduction, there is theory overview about programming language J2ME, its parts and divisions in couple of chapters. The applications developing begin by choosing focus groups and also group of devices that agree with present trends about mobile devices. The next part undertakes selecting development tool NetBeans IDE based on requirements for multimedia develop and also undertakes selecting software development kit Nokia SDK and its short definition. Aft

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Paquet-Durand, Tanja [Verfasser]. "Functional characterization of the protease ClpQ in transgenic Plasmodium berghei in immunologically different murine hosts / Tanja Paquet-Durand." Gießen : Universitätsbibliothek, 2011. http://d-nb.info/1068824697/34.

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Rickerson, Nancy L. "Postsecondary success for culturally and linguistically diverse (CLD) students with disabilities : access and persistence issues /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/7565.

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Daňko, Matúš. "Stanovení spektra zatížení a únavové životnosti malého dvoumístného kompozitního letounu." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2018. http://www.nusl.cz/ntk/nusl-377752.

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Primary goal of this thesis is to present proposed method for fatigue life evaluation applicable to light composite aircraft. The first chapter of this thesis is focused on certification specifications and requirements for fatigue life proof of structure. Significant part of this thesis is dedicated to fatigue life evaluation and guideline how to proceed in evaluation of fatigue data. Thesis also points out on possible methods of statistical fatigue data analysis and critical parts of structure in means of fatigue life. The last part of thesis is focused on design of experimental evaluation of

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Alkhafaf, Farah. "Culturally and Linguisitcally Diverse Students and Acculturative Stress." University of Dayton / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1628250889635965.

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Saint-Hilaire, Maïlie. "Toxicocinétique de la chlordécone chez la brebis." Thesis, Université de Lorraine, 2018. http://www.theses.fr/2018LORR0256.

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Aux Antilles Françaises, les animaux d’élevage sont susceptibles d’être exposés à la chlordécone (CLD), Polluant Organique Persistant (POP) présent dans leur environnement. Afin de sécuriser les Denrées Alimentaires d’Origine Animale (DAOA) destinées à la consommation humaine, nos travaux ont porté sur l’étude du devenir de la CLD chez la brebis. Les objectifs de ces travaux étaient de comprendre comment s’effectue l’élimination de la molécule depuis l’organisme animal c’est-à-dire de déterminer par quelle(s) voie(s), sous quelle(s) forme (s), en combien de temps, en quelle quantité et par que

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Robert, Thierry. "Le Québec à l'âge des loisirs l'évolution de la représentation du loisir pour la jeunesse dans le discours de la Confédération des loisirs du Québec de 1961 à 1978." Mémoire, Université de Sherbrooke, 2008. http://savoirs.usherbrooke.ca/handle/11143/2585.

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Ce mémoire étudie les représentations du loisir durant les années 1960 et 1970 au Québec pour un groupe d'âge bien particulier: la jeunesse. Nous examinons le discours sur les temps libres à partir des revues Bulletin-Loisirs et Loisir-Plus, publiées par la Confédération des Loisirs du Québec (CLQ). Éduquer, occuper ou faire plaisir aux jeunes, les auteurs des deux revues montrent différentes conceptions du temps libre. Sa place, son rôle, ses objectifs et ses valeurs sont tributaires d'une vision sociale cherchant à réguler la liberté inhérente aux loisirs. Plus précisément, nous tenterons de

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Cabral, Robin Morales. "Student learning behaviors and intervention practices cited among Midwestern teachers referring bilingual CLD students for special education evaluation." Diss., Manhattan, Kan. : Kansas State University, 2008. http://hdl.handle.net/2097/932.

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Yehya, Sarah. "Modulation de l’absorption intestinale de la chlordécone (CLD) par l’utilisation de substances séquestrantes : application à l’élevage en zones contaminées." Thesis, Université de Lorraine, 2017. http://www.theses.fr/2017LORR0259/document.

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La contamination des sols agricoles par la chlordécone menace la durabilité de l’élevage de plein air aux Antilles. Afin de maintenir ce dernier tout en protégeant les consommateurs de denrées animales d’origine terrestre, plusieurs stratégies sont étudiées. Ces travaux de thèse sont focalisés sur l’une d’entre elles qui consiste à séquestrer la chlordécone afin de réduire significativement sa biodisponibilité pour l’animal. La démarche expérimentale a été réalisée par étape, elle s’appuie sur trois piliers : des matières séquestrantes carbonées de type biochar ou charbon activé, l’utilisation

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Růčka, Lukáš. "Příjem a posílání SMS zpráv pomocí aplikace určené pro platformu JavaME." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2008. http://www.nusl.cz/ntk/nusl-217265.

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The aim of this diploma thesis is to study the potential of Java ME platform for receiving and sending of SMS and to utilize obtained information subsequently in implementation of an application for this platform. The first part of the diploma thesis aims at explaining general terms of the Java language and its basic features. The next part deals with specific properties of the Java ME platform and properties of devices that support this platform. A design of the Java ME application based on theoretical knowledge is created then. This application has to be able to receive, process, store and s

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Marnissi, Imed Eddine. "Impact du micro financement sur le développement économique local : le cas du CLD de la MRC du Haut-Saint- François." Mémoire, Université de Sherbrooke, 2001. http://savoirs.usherbrooke.ca/handle/11143/290.

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L'objectif principal de ce mémoire de recherche et [i.e. est] de mesurer l'impact des institutions de la micro finance sur le développement économique local et ce à travers le recourt au concept d'entrepreneuriat. La revue de littérature que nous présentons, nous permet de préciser ce que l'on entend par micro finance, entrepreneuriat et développement local. Elle nous fournit aussi l'occasion d'expliquer le lien qui existe entre ces trois concepts primordiaux de notre recherche. Notre démarche pratique pour mesurer le rôle des institutions de micro finance dans le développement économique loca

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Marnissi, Imed Eddine. "Impact du micro financement sur le développement économique local : le cas du CLD de la MRC du Haut-Saint-François." Sherbrooke : Université de Sherbrooke, 2001.

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La, Porta Viscardo Pio Pietro. "Progettazione e sviluppo di un videogioco J2ME per dispositivi mobili." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2010. http://amslaurea.unibo.it/1642/.

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Ström, Simon. "Samrådsunderlag för Lysekilsprojektet : Forskning och utveckling av vågkraft." Thesis, Stockholms universitet, Institutionen för naturgeografi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-114303.

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The aim of this research is to find out what environmental impact a wave power park has on the Swedish west coast by creating a consultation paper (”Samrådsunderlag”) for the Lysekilproject at Uppsala University. To highlight the complexity of the problem a system analytic approach was used and illustrated by a Causal Loop Diagram. The overall assessment of the Lysekilprojects wave power park at the Swedish west coast is that it will have a low impact on the environment. This is due to the relative small size of the wave power park and some technical solutions made with the environmental aspec

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Rauff, Bisma. "In vitro and in vivo models to investigate the mechanisms of liver fibrosis and cholestasis." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/16717.

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Chronic liver disease (CLD) is a leading cause of mortality around the world and can arise from a range of injuries or insults. Untreated CLD results in liver fibrosis and ultimately can lead to the development of liver cancer. Primary liver cancers include hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA). Every year approximately 700,00 people die of liver cancer, making it the third most common cause of cancer death, worldwide (Ferlay et al., 2010). To date, drugs targeting these aggressive cancers have shown minimal benefit in clinical trials and cause a range of side effects. Th

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Zigler, David Michael. "Use of CRT Lenses in the Reduction of Dry Eye Symptoms in Symptomatic Soft Contact Lens Wearers." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1397561890.

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Figurny, Radek. "Lokalizace pomocí aplikace určené pro platformu Java ME využívající GPS." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2009. http://www.nusl.cz/ntk/nusl-218080.

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The task of the Master's thesis has been to develop the MIDlet, which is able to receive data from an external GPS module via Bluetooth. Data are received in the NMEA 0183 format and are processed to extract longitude, latitude, elevation, velocity, number of visible satellites and measurement accuracy of longitude, latitude and elevation. Users have a possibility to save their actual location with a short description to the cell phone’s memory. The MIDlet is also able to save a user defined way-point and navigate to this way-point. The MIDlet itself was developed in the Netbeans IDE with a so

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Madry, Martin. "Systémová dynamika: případ výkonnosti projektových týmů." Master's thesis, Vysoká škola ekonomická v Praze, 2014. http://www.nusl.cz/ntk/nusl-193285.

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This thesis deals with modelling of project teams and their behavior using the principles of system dynamics. Main goal of this thesis is to create a model using system dynamics, which will allow to simulate how projects are finished. Results from the model are going to be used to define the best possible strategy to finish a project in required time. Theoretical part of this work is composed of presentation of project management and further the thesis extensively describes system dynamics, principles of system dynamics, used diagrams and possible ways of application of system dynamics in the

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Frahm, Ashley Elizabeth. "Norming a Dynamic Assessment of Narrative Language for Diverse School-Age Children With and Without Language Disorder: A Preliminary Psychometric Study." BYU ScholarsArchive, 2021. https://scholarsarchive.byu.edu/etd/8935.

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The purpose of this study was to investigate preliminary psychometric normative data of an English dynamic assessment of narrative language for a group of diverse school-age students with and without language disorder. This study included 364 diverse students with and without language disorder ranging from kindergarten through 6th grade. Students were confirmed as having a language disorder if they had an existing active IEP for language, and scores below a certain cutoff point on a nonword repetition (NWR) task and the narrative language measure (NLM). English language proficiency was investi

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Bahadir, Mesut. "Developing Jxta Applications For Mobile Devices And Invoking Web Services Deployed In Jxta Platform From Mobile Devices." Master's thesis, METU, 2004. http://etd.lib.metu.edu.tr/upload/12605823/index.pdf.

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Today, Peer-to-peer (P2P) computing and Web Services play an important role in networking and computing. P2P computing, that aims addressing all the resources in a network and sharing them, is an old paradigm that gains importance nowadays with the advent of popular file sharing and instant messaging applications. On the other hand, a Web service is a software system that has an interface allowing applications to interact with other applications through Internet or intranet. Providing methods for publishing and discovering Web services from which mobile devices can facilitate in a P2P environm

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Salomón, Hernández Luis Armando. "Autour de la quantification fonctionnelle de processus gaussiens." Toulouse 3, 2011. http://thesesups.ups-tlse.fr/1444/.

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Cette thèse a pour objectif principal l'étude de résultats asymptotiques autour de la quantification fonctionnelle. Après les résultats obtenus pour Sagna sur le rayon maximal du quantifier optimal en dimension finie, nous cherchons l'asymptotique du rayon maximal en dimension infinie, spécifiquement pour le mouvement brownien. Nous présentons aussi un nouvel algorithme stochastique en dimension finie pour trouver des quantifiers stationnaires. Nous proposons une nouvelle méthode d'estimation pour le paramètre de Hurst dans des processus gaussiens fractionnaires plus robuste pour le calcul num

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Limmerstedt, Carolina, and Elisabeth Lyhre. "Dynamic Assessment of the narrative ability in a group of South African preschool children." Thesis, Uppsala universitet, Logopedi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-166577.

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Standardized tests are generally based on the norms of the majority population who share the same culture, language and above all, similar prior learning experiences. Because of this, it is problematic for clinicians to use standardized tests when assessing children from culturally and linguistically diverse (CLD) backgrounds. Dynamic assessment (DA) is an alternative assessment method that can circumvent the dilemma of biased testing of children from CLD populations. By looking at the child‟s modifiability instead of static performance DA aims to target the child‟s true language ability. In t

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Frick, Bethany Joan. "Multicultural Considerations in Augmentative and Alternative Communication (AAC) Devices for Culturally and Linguistically Diverse AAC Users." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1585242427166751.

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Kubina, Tomáš. "Rozhraní pro skupinové odesílání SMS v JavaME." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2008. http://www.nusl.cz/ntk/nusl-217718.

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This Diploma Thesis have been describing possibilities of Wireless Messaging API, which are used for applications handling with Short Messages. It have been describing basics of programming language JavaME, basics of formating and sending SMS, detailed analysis of Wireless Messaging API, application, which is part of my diploma thesis and finally Security Politics of JavaME programming language.

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Wilson, Patrice C. "THE RELATIONSHIP BETWEEN TEACHERS’ LEVELS OF CULTURAL COMPETENCE AND THE NOMINATION/REFERRAL PROCESS FOR GIFTED IDENTIFICATION OF CULTURALLY AND LINGUISTICALLY DIVERSE STUDENTS." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/3428.

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This study examined the extent to which teachers’ levels of cultural competence is a factor in the nomination/referral process for gifted identification of culturally and linguistically diverse students. Specifically, this study compared the self-assessed perceptions of second and third grade elementary teachers’ cultural competence to the various factors included in the gifted referral process. A quasi-experimental quantitative study was used. However, this study superficially included some qualitative exploration due to the nature of the open-ended survey questions and secondary data set

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Nguyen, Quan Van, and Nam Cao Nguyen. "Systems thinking methodology in researching the impacts of climate change on livestock industry." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-126825.

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The impacts of climate change on livestock production are complex problems, existing in the rela-tionship among this sector and others sectors such as environmental, social, economic and political systems. The complexity and dynamic of these impacts cannot be solved simply in isolation with the linear approach. A system thinking methodology is introduced in this paper to understand the impacts of climate change on livestock production, and identify effective interventions strategies to address this systemic problem. System thinking is a way of thinking about the world and relationships which h

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Bandreddy, Naga Abhiram. "Defining Correlation Between Radon, Uranium Deposits, and Oil and Gas Wells Using GIS Regression Methods." University of Toledo / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1564687565423414.

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Villca, Pozo Ariel Rey. "Utilización de geopolímero para la mejora de las propiedades en morteros cal-puzolana y su empleo en países en desarrollo." Doctoral thesis, Universitat Politècnica de València, 2021. http://hdl.handle.net/10251/172663.

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[ES] El descubrimiento del cemento Portland ha cambiado nuestra forma de construir, pero también es el responsable de grandes emisiones de CO2 a la atmósfera durante su fabricación (~1450 ᴼC), agravando la crisis actual que está sufriendo nuestro planeta debido al cambio climático y sus consecuencias en todo el medio ambiente. Por lo tanto, una alternativa más sostenible en la construcción es la utilización de la cal que necesita menor temperatura para su fabricación (~900 ᴼC). Si bien la introducción de puzolanas naturales o artificiales en morteros de cal han mejorado sus propiedades mec

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Price, Gaylene. "Scaffolding teacher learning : examining teacher practice and the professional development process of teachers with culturally and linguistically diverse (CLD) learners : a dissertation submitted to the College of Education, University of Canterbury at Christchurch in partial fulfilment of the requirement of the degree of Master of Teaching and Learning EDTL 904, University of Canterbury /." Thesis, University of Canterbury. Educational Studies and Human Development, 2008. http://hdl.handle.net/10092/2682.

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Teachers work in complex and demanding times with an increasing number of students from culturally and linguistically diverse backgrounds (CLD) in classrooms. These students are over represented in statistics of under achievement. All teachers are teachers of academic language, and while no child is born with school language as a first language, for some students the match between home and school is more closely aligned than for other students. Teachers are expected to be culturally responsive, ensuring the languages and culture of students is visible in the classroom environment and the clas

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Czapek, Jakub. "Stavba-Prostor-Město "Dostavba městského bloku"." Master's thesis, Vysoké učení technické v Brně. Fakulta architektury, 2019. http://www.nusl.cz/ntk/nusl-400655.

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The diploma thesis deals with the creation of a design of a new apartmen building in the city of Brno on the plot expected to be completed by the city block. Typologically it deals with the current design possibilities of gallery apartment buildings / porch houses, implementation of space-demanding grocery stores and commercial areas into urban structures. Architecturally explores the possibilities of designing new constructions with citation of architectural language a tectonics of past styles.

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Павлик, Анатолій Володимирович, Анатолий Владимирович Павлик та Anatolii Volodymyrovych Pavlyk. "Еколого-економічне оцінювання ефективності використання відновлювальних джерел енергії". Thesis, Сумський державний університет, 2019. http://essuir.sumdu.edu.ua/handle/123456789/75092.

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У дисертації вдосконалені наукові засади оцінювання еколого-економічної ефективності впровадження ВДЕ, що враховують екологічні та економічні наслідки їх використання. Це дозволило визначити оптимальну структуру забезпечення електричною енергією національної економіки. Виявлені причинно-наслідкові зв’язки між екодеструктивним впливом на навколишнє середовище та енергетичною, екологічною і економічною безпекою країни. Розвинуто науково-методичний підхід до формування організаційно-економічного механізму впровадження економічно доцільних та екологічно безпечних ВДЕ. Запропоновано методичний підх

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Saint-Hilaire, Maïlie. "Toxicocinétique de la chlordécone chez la brebis." Electronic Thesis or Diss., Université de Lorraine, 2018. http://www.theses.fr/2018LORR0256.

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Aux Antilles Françaises, les animaux d’élevage sont susceptibles d’être exposés à la chlordécone (CLD), Polluant Organique Persistant (POP) présent dans leur environnement. Afin de sécuriser les Denrées Alimentaires d’Origine Animale (DAOA) destinées à la consommation humaine, nos travaux ont porté sur l’étude du devenir de la CLD chez la brebis. Les objectifs de ces travaux étaient de comprendre comment s’effectue l’élimination de la molécule depuis l’organisme animal c’est-à-dire de déterminer par quelle(s) voie(s), sous quelle(s) forme (s), en combien de temps, en quelle quantité et par que

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Rivera, Christopher J., Bree A. Jimenez, Joshua N. Baker, Tracy Spies, Pamela J. Mims, and Ginevra Courtade. "A Culturally and Linguistically Responsive Framework for Improving Academic and Postsecondary Outcomes of Students with Moderate or Severe Intellectual Disability." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/301.

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The needs of culturally and linguistically diverse (CLD) students with moderate or severe intellectual disability (ID) are quite unique and complex. CLD students with moderate or severe ID face many of the same issues as their non-disabled CLD peers; however, due to the nature of their disability this may lead to even less access to the general curriculum, appropriate services, materials, and meaningful collaboration between families and educators. The purpose of this article is to provide a culturally responsive framework for facilitating academic instruction for CLD students with moderate or

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LENAKAKI, Angeliki. "Why do Traditional Performance Management Systems in Healthcare not always lead to Improved Performance? Outlining the Unintended Consequences of the Greek Healthcare Reform in a Public Hospital through a Dynamic Performance Management Approach." Doctoral thesis, Università degli Studi di Palermo, 2021. http://hdl.handle.net/10447/514805.

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Researchers all around the globe have not yet come to an end as regards the supposed positive impact of traditional performance management systems in healthcare, and some research has shown that, paradoxically, performance management policies do not always lead to improved hospital performance. Despite the extensive research identifying the “pitfalls” of the NPM reforms around Europe and the unintended consequences for hospital staff and patients, little is known about the mechanisms that caused those negative effects, which essentially creates a research gap worth investigating. This PhD stud

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Pahle, Jessica. "Oncoleaking gene therapy: a new suicide approach for treatment of pancreatic cancer." Doctoral thesis, Humboldt-Universität zu Berlin, 2018. http://dx.doi.org/10.18452/19298.

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Bakterielle Toxine stellen eine wirkungsvolle und effektive Alternative zur Therapie von Tumorerkrankungen dar. Das vom Clostridium perfringens Typ A produzierte Clostridium perfringens enterotoxin (CPE) gehört zu der Gruppe der porenbildenden Toxine und weist eine rezeptorspezifische zytotoxische Wirkung auf, welche über die Membranrezeptoren Cldn3 und Cldn4 entfaltet wird. Diese liegen vor allem in Epithelialkarzinomen wie dem Brust-, Prostata-, oder Kolon-, sowie dem Pankreaskarzinom (PK) stark hochreguliert vor. Ziel dieser Arbeit war die Anwendung des neuen selektiven und effizienten „O

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Chicherova, Ievgeniia. "Netrin-1 and neurons in hepatocellular carcinoma." Electronic Thesis or Diss., Lyon, 2022. https://n2t.net/ark:/47881/m60r9pbg.

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L'inflammation hépatique chronique peut entraîner des maladies chroniques du foie (MCF), notamment l'hépatite, la cirrhose et le carcinome hépatocellulaire (CHC), qui est la tumeur maligne primaire du foie la plus fréquente et le troisième cancer le plus fréquent en termes de mortalité dans le monde. Indépendamment des facteurs étiologiques, toutes les MCFs partagent de nombreux mécanismes physiopathologiques communs : réponse aux protéines non pliées (UPR), inflammation chronique et fibrose. A l'aide d'un modèle animal et d'échantillons cliniques nous avons étudié un autre dénominateur commun

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Lian, Shiang-Yung, and 連湘芸. "Regulation of clpQ+clpY+ gene expression." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/j2k83h.

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碩士<br>國立臺灣大學<br>農業化學研究所<br>90<br>The ClpYQ proteases are heat shock proteins, and σ factors, for example, σ32, σ38 andσ70, are necessary for gene expression. Previous studies demonstrated that an overexpression of σ32 can induce the clpQ+clpY+ expression to ten fold. There are three consensus binding sites for σ32, σ38 and σ70 on the promoter of the clpQ+clpY+ operon. In this study, we try to understand under what conditions that clpQ+clpY+ operon can be induced by σ factors. We made a promoter fusion gene, clpQ::lacZ, and constructed strains carrying the fusion gene and having σ

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Pai, Chia-Yun, and 白家芸. "Design of Java AWT for Java ME CLDC Platforms." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/53598173033024605521.

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碩士<br>國立交通大學<br>資訊科學與工程研究所<br>101<br>As the trend, Java embedded system is more and more important evolvement. Graphics user interface(GUI) is accompanied with this trend. Advance technology is not common to the public, and it’s not really convenient in practice. Combined above two directions, GUI system in Java embedded environment is a growing research topics in the future. According to Java AWT in JavaME CDC/PBP，we simplified the Java AWT classes, and remains most part of API, and designs a GUI system for JavaME CLDC, named MMES AWT. Compared with Java AWT in JavaME CDC/PBP, MMES AWT has le

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Mengching, Chen, and 陳盟靜. "An analysis of subunit interaction of ClpQ/ClpQ molecules and searching for interactive molecules of ClpYQ protease in E.coliby using yeast two-hybrid system." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/10700170218190182345.

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碩士<br>國立臺灣大學<br>農業化學研究所<br>90<br>The E.coli ClpYQ protease are consisted of ClpY and ClpQ, and are heat shock proteins. The large subunit, ClpY, is 49 kDa; and the small subunit, ClpQ is 19 kDa. The ClpY and ClpQ individually form identical homo-ring structures in vitro and assemble into a four ring ClpYQ complex. I used the yeast two-hybrid methods to analyze an interaction domain within ClpQ molecules. The ClpQ 133th amino acid alanine mutated to threonine decreases the interaction. The results from assays of the interactions between the ClpQ deletion mutant and itself, suggest

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Lin, Pei-I., and 林佩宜. "ClpQ subunit oligomerization and its C domain function in Escherichia coli." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/88492527344822156255.

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碩士<br>國立臺灣大學<br>農業化學研究所<br>94<br>Abstract The E. coli ClpQY (HslVU) is an ATP-dependent protease that consists of an ATPase large subunit and a peptidase small subunit. The function of ClpQY protease is as a chaperon in refolding of misfolded peptides and as a protease to catalyse the degradation of abnormal proteins as well. Six identical subunits of both ClpQ and ClpY self-assemble into an oligomeric ring and two rings of each subunit form a dumbbell shape complex, two ClpQ rings surrounded by two ClpY single rings. Construction of the fusion gene of P. aeruginosa and E. coli clpQ was used

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Couto, Manuela Maria André de Sousa. "O desporto escolar como componente educativa nas escolas integrantes CLDE Tâmega." Master's thesis, 2013. http://hdl.handle.net/10348/7040.

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Dissertação de Mestrado em Ensino de Educação Física, nos Ensinos Básico e Secundário<br>As alterações ocorridas na estrutura social e económica das sociedades têm vindo a criar transformações nos hábitos quotidianos e nos valores dos indivíduos com implicações na ocupação do tempo livre e consequentemente nas oportunidades lúdicas oferecidas à criança. As práticas desportivas e o desporto escolar como actividades de ocupação de tempos livres e de lazer, têm uma relevância de destaque quando falamos de crianças e jovens. O tempo livre da criança passou a ser uma questão problemática de or

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WU, TING-HUA, and 吳亭樺. "Augmented expression of CLDN-1 reduces colonization ability of nasopharyngeal carcinoma cells." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/jq5wn7.

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碩士<br>慈濟大學<br>生命科學系碩士班<br>105<br>Claudin superfamily has been demonstrated an important role in cell to cell communication. Of interest, numerous evidences reveal that abnormal expression of claudins, such as claudin-1 contributed to tumor progression. Previous study demonstrated claudin-1 expression confers resistance to cell death of nasopharyngeal carcinoma (NPC) cells. However, the mechanism is still not clear. In this study, exogenous expression of claudin-1 in NPC cells was utilized to assess effect of claudin-1 in tumor cells. Via anchorage independent assay and 3-D tumor spheroid forma

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Yu, Chien-Hung, and 余建泓. "The ClpQ C-domain is responsible for subunit interaction in E. coli." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/91831414212216407589.

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碩士<br>國立臺灣大學<br>農業化學研究所<br>92<br>In response to heat shock and other stressful conditions, cells increase the synthesis of a group of proteins known as heat shock proteins (Hsps). The heat shock proteins function either as molecular chaperons in the refolding of misfolded peptides or as proteases which catalyse the degradation of such abnormal proteins. ClpQY (HslVU) is one of the Hsps in E. coli which is a multimeric complex of two components encoded in the hslVU operon: the proteolytic component ClpQ (HslV) is about 19kDa and the ATPase ClpY (HslU) is about 50kDa. Negatively staining elec

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Belzile, Martin. "Les centres locaux de développement (CLD) et le développement de l'entrepreneuriat en milieu périphérique : le cas du CLD Lac-Saint-Jean Est." Mémoire, 2009. http://www.archipel.uqam.ca/2251/1/M10937.pdf.

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Cette recherche a pour but de présenter une étude de cas d'un organisme de développement local à l'intérieur d'un milieu périphérique. Cette recherche tente de cerner les impacts de la présence d'un tel organisme sur son territoire d'intervention. Pour ce faire, nous avons retenu le CLD Lac-Saint-Jean Est dans la région du Saguenay-Lac-Saint-Jean. Celle-ci présente les traits typiques d'un milieu périphérique: secteur traditionnel en déclin, taux de chômage élevé, dévitalisation du milieu rural, etc. Cette recherche vise plusieurs objectifs. Dans un premier temps, déterminer les outils d'inter

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