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Journal articles on the topic 'Cleft palate'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Lasma Azaria, Yohana. "MANAGEMENT IN CLEFT LIP AND PALATE SURGERY : A SYSTEMATIC REVIEW." Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425) 9, no. 4 (2023): 28–33. http://dx.doi.org/10.53555/nnmhs.v9i4.1646.

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Cleft lip and palate, sometimes referred to as labioplatoschizis, is one of the most common types of congenital disorders found in Indonesian babies. A person is said to have cleft lip and cleft palate if they have a cleft in their upper lip as well as a cleft in the roof of their mouth, which results in a direct connection between their nostril and mouth. This condition is also known as cleft lip and palate syndrome. This disorder could be hereditary or it could be acquired. Both the cleft lip and the cleft palate can happen on their own (just the cleft lip or just the cleft palate), or they

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Russell, Kathleen A., Victoria M. Allen, Mary E. MacDonald, Kirsten Smith, and Linda Dodds. "A Population-Based Evaluation of Antenatal Diagnosis of Orofacial Clefts." Cleft Palate-Craniofacial Journal 45, no. 2 (2008): 148–53. http://dx.doi.org/10.1597/06-202.1.

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Objectives: To evaluate the changes in prevalence and antenatal detection of cleft lip with or without cleft palate and isolated cleft palate and to describe the association between anomalies and rates of antenatal diagnosis in Nova Scotia from 1992 to 2002. Design: This population-based cohort study employed the Nova Scotia Atlee Perinatal Database, the Fetal Anomaly Database, and IWK Cleft Palate Database in Halifax, Nova Scotia, Canada. Outcome Measures: Cleft type, mode of diagnosis, and associated abnormalities of orofacial clefts for liveborn infants, stillbirths, and second trimester te

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3

Dr., Shah Rukh Saleem Dr. Azeem Ahmed Dr. Sufyan Akram. "UPDATING GENETICS POLYMORPHISMS OF NON-SYNDROMIC CLEFTS LIP-PALATES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 11 (2018): 12305–9. https://doi.org/10.5281/zenodo.1489198.

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<em>NSCLP/CP (Non-Syndromic Clefts Lip-Palates) is the most general congenital distortion throughout the globe, with highly significant social and psychic effects. NSCLP/CP (Non-Syndromic Clefts Lip-Palates formation happens from the genetic factors and environmental interactions and this study will try to deliver recent progress review while defining the NSCLP/CP (Non-Syndromic Clefts Lip-Palates genetic causes. </em> <em>A literature review was directed through the Medline Database according to a search regarding following keywords: non-syndromic, genes, cleft lip-palate and genetics of clef

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Heliövaara, Arja, and Jorma Rautio. "Craniofacial and Pharyngeal Cephalometric Morphology in Seven-Year-Old Boys with Unoperated Submucous Cleft Palate and without a Cleft." Cleft Palate-Craniofacial Journal 46, no. 3 (2009): 314–18. http://dx.doi.org/10.1597/07-211.1.

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Objective: To evaluate cephalometrically the craniofacial and pharyngeal morphology in 7-year-old boys with unoperated submucous cleft palate and to compare the findings with the morphology of 7-year-old boys without clefts. Setting and Patients: Thirty-two boys with unoperated submucous cleft palate and 49 boys without a cleft were compared retrospectively from lateral cephalograms taken at the mean age of 7 years (range, 5.5 to 8.6 years). Design: A retrospective case-control study. Outcome Measure: Linear and angular measurements were obtained from lateral cephalograms. A Student's t test w

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5

Agbenorku, P., M. Yore, K. A. Danso, and C. Turpin. "Incidence of Orofacial Clefts in Kumasi, Ghana." ISRN Plastic Surgery 2013 (May 15, 2013): 1–6. http://dx.doi.org/10.5402/2013/280903.

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Background. Cleft lip and cleft palate are among the most common orofacial congenital anomalies. This study is to establish Orofacial Clefts Database for Kumasi, Ghana, with a view to extend it to other cities in future to obtain a national orofacial anomaly database. Methods. A descriptive prospective survey was carried out at eleven selected health facilities in Kumasi. Results. The total number of live births recorded was 27,449. Orofacial anomalies recorded were 36, giving an incidence of 1.31/1000 live births or 1 in 763 live births. The mean maternal age of cleft lip/palate babies was 29

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6

Stahl, Franka, Rosemarie Grabowski, and Katrin Wigger. "Epidemiology of Hoffmeister's “Genetically Determined Predisposition to Disturbed Development of the Dentition” in Patients with Cleft Lip and Palate." Cleft Palate-Craniofacial Journal 43, no. 4 (2006): 457–65. http://dx.doi.org/10.1597/04-156.1.

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Objective Type and prevalence rates of the symptoms of Hoffmeister's “genetically determined predisposition to disturbed development of the dentition” were studied in patients with clefts. Patients Data of 263 patients with nonsyndromic clefts of lip (alveolus and palate) or isolated cleft palates were examined in a retrospective study. Setting The clefts were classified as cleft lip or cleft lip and alveolus, cleft palate, unilateral cleft lip and palate, and bilateral cleft lip and palate. All patients were scrutinized for 28 individual symptoms. Prevalences of the individual symptoms were s

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Ortiz-Posadas, M. R., L. Vega-Alvarado, and J. Maya-Behar. "A New Approach to Classify Cleft Lip and Palate." Cleft Palate-Craniofacial Journal 38, no. 6 (2001): 545–50. http://dx.doi.org/10.1597/1545-1569_2001_038_0545_anatcc_2.0.co_2.

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Objective: To propose a new method, which allows for a complete description of primary and secondary cleft palates, incorporating elements that are related to the palate, lip, and nose that will also reflect the complexity of this problem. Method: To describe the type of cleft, two embryonic structures were considered: (1) the primary palate, formed by the prolabium, premaxilla, and columella and (2) the secondary palate, which begins at the incisive foramen and is formed by a horizontal portion of the maxilla, the horizontal portion of the palatine bones, and the soft palate. Anatomical chara

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8

Forrester, Mathias B., and Ruth D. Merz. "Structural Birth Defects Associated with Oral Clefts in Hawaii, 1986 to 2001." Cleft Palate-Craniofacial Journal 43, no. 3 (2006): 356–62. http://dx.doi.org/10.1597/04-190.1.

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Objective To identify structural birth defects that occur in association with oral clefts. Methods Data were obtained from a birth defects registry and included all infants and fetuses with cleft palate without cleft lip or cleft lip with or without cleft palate delivered from 1986 to 2001. For 47 specific structural birth defects, rates among oral cleft cases were compared with the rates among all infants and fetuses with major birth defects, excluding those with oral clefts. Results Among cleft palate only cases, the rates were significantly higher than expected for encephalocele, microcepha

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9

Corcoran, Mirjami, Saujanya Karki, Leena Ylikontiola, Riitta Lithovius, George K. Sándor, and Virpi Harila. "Maxillary Arch Dimensions in 6-Year-Old Cleft Children in Northern Finland: A Cross-Sectional Study." International Journal of Environmental Research and Public Health 18, no. 14 (2021): 7432. http://dx.doi.org/10.3390/ijerph18147432.

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The aim was to cross-sectionally examine the maxillary arch dimensions in 6-year-old children with cleft lip and/or palate and to compare them with the initial cleft sizes among patients with cleft palate. The study included 89 patients with clefts treated at the Oulu University Hospital. The subjects were divided into three groups: cleft palate, cleft lip, and cleft lip and palate. Study casts were scanned, and the maxillary arch dimensions were examined using a 3D program (3Shape Orthoanalyzer, Copenhagen, Denmark). The statistical methods Student’s t-test and one-way ANOVA were used to comp

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Zubair Ahmed Abbasi, Syeda Arzoo Azeem, Shazia Sarwat Iqbal, Syed Mahmood Shah, and Zafar Abbas. "An Assessment of Pattern of Distribution of Cleft Lip and Palate Patients Reported to A Tertiary Care Hospital in Karachi, A Retrospective Study." ANNALS OF ABBASI SHAHEED HOSPITAL AND KARACHI MEDICAL & DENTAL COLLEGE 26, no. 4 (2021): 212–16. http://dx.doi.org/10.58397/ashkmdc.v26i4.440.

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Abstract Objective:  To evaluate the patterns of cleft lip and palate by its type, side, gender, laterality and extent of involvement of hard and/or soft palate in patients reported to a tertiary care hospital in Karachi. Methods: This retrospective study was conducted from January 2016 to January 2017 at Saifee hospital Karachi. It includes patient’s data from December 2014 till December 2015. Total 198 patients with diagnosed cleft lip and /palate anomaly were included in the study. Data was collected by patient record forms and relevant findings were recorded on a pr

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11

Inoue, Hiroki, Shuji Kayano, Yoko Aoki, et al. "Association of the GABRB3 Gene with Nonsyndromic Oral Clefts." Cleft Palate-Craniofacial Journal 45, no. 3 (2008): 261–66. http://dx.doi.org/10.1597/06-142.

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Objective: Nonsyndromic oral clefts are common craniofacial anomalies classified into two subgroups: cleft lip with or without cleft palate and isolated cleft palate. Nonsyndromic oral clefts are multifactorial diseases, with both genetic and environmental factors involved in their pathogenesis. The inhibitory neurotransmitter, γ-aminobutyric acid plays a role in normal embryonic, and particularly facial, development and γ-aminobutyric acid receptor type A β-3 subunit (GABRB3) knockout mice have been shown to have cleft palate. The GABRB3 gene is therefore a strong candidate gene for nonsyndro

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Kulesa-Mrowiecka, Małgorzata, Anna Lipowicz, Bożena Anna Marszałek-Kruk, et al. "Characteristics of Factors Influencing the Occurrence of Cleft Lip and/or Palate: A Case Analysis and Literature Review." Children 11, no. 4 (2024): 399. http://dx.doi.org/10.3390/children11040399.

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Introduction: Cleft lip with or without cleft palate (CL/P) stands as the most common congenital facial anomaly, stemming from multifactorial causes. Objective: Our study aimed to ascertain the prevalence and characteristics of cleft palates, identify associated risk factors to inform prevention and prenatal detection for early intervention, and assess postoperative rehabilitation protocols for cleft palates. Design: This study employs a retrospective descriptive and clinical approach. Patients: The study includes 103 children with cleft palates treated at the Department of Head and Neck Surge

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13

Schmidt, Gül, Elena Hofmann, Friedrich Mrosk, et al. "Minimizing Palato/velar Fistulas: A New Anatomic Perspective on Unilateral Cleft Lip and Palate." Plastic and Reconstructive Surgery - Global Open 13, no. 2 (2025): e6556. https://doi.org/10.1097/gox.0000000000006556.

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Background: Unilateral cleft lip and palates present unique anatomy at the palato-velar-vomerine junction. This region can be the widest and most challenging part of the cleft, where functional fistulas may occur. In 2017, an approach concentrating on the nasal part was implemented, which rendered the repair of this transition zone less challenging. This study detailed this surgical modification, which allows easy and effective palate repair and thereby reduces fistula rates. Methods: This study included 71 patients with unilateral cleft lip and palates who underwent 1-stage palatal repair usi

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Kalisya, Luc Malemo, Jacques Fadhili Bake, Bake Elisee, et al. "Surgical Repair of Orofacial Clefts in North Kivu Province of Eastern Democratic Republic of Congo (DRC)." Cleft Palate-Craniofacial Journal 57, no. 11 (2020): 1314–19. http://dx.doi.org/10.1177/1055665620947604.

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Background: There is a high prevalence of orofacial clefts in low- and middle-income countries with significant unmet need, despite having 50% of the population younger than 18 years in countries such as the Democratic Republic of Congo (DRC). The purpose of this article is to report on the experience of general surgeons with orofacial clefts at a single institution. Methods: This is a retrospective study of patients treated for cleft lip/palate in the province of North Kivu, DRC between 2008 and 2017. Results: A total of 1112 procedures (122/year) were performed. All procedures were performed

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*Dr., Ghulam Hussain *Dr. Mehr-un-Nisah. "STUDY TO KNOW THE SURGICAL TREATMENT AND CLINICAL FEATURES OF CLEFT LIP AND PALATE." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 06, no. 01 (2019): 329–34. https://doi.org/10.5281/zenodo.2530863.

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<strong><em>Objective:</em></strong><em> The aim of this study was to know the surgical treatment and clinical features of the cleft lip and palate.</em> <strong><em>Study design: </em></strong><em>A Prospective Study.</em> <strong><em>Location and Duration: </em></strong><em>In the Oral and Maxillofacial Surgery Department of Mayo Hospital Lahore for one year duration from July 2017 to July 20018.</em> <strong><em>Methodology:</em></strong><em> A total of 50 patients with congenital cleft lip and palate were treated in the oral and maxillofacial surgery department. The cleft in the lip was re

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Nouri, Dr Muyesser Abdulkarem, Dr Shehab Ahmed Hamad, and Dr Nazdar Ezzaddin Rasheed. "Incidence of Cleft Lip and Palate in Erbil City." Mustansiria Dental Journal 7, no. 1 (2018): 106–12. http://dx.doi.org/10.32828/mdj.v7i1.383.

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Aims: This study was conducted to assess the epidemiology and some of the possiblerisk factors causing cleft lip and palate in Erbil city.Materials and Methods: the data were obtained from the records of Raparinpaediatric and maternity hospital in the center of Erbil city. The file records oflive births during a period from January 2000 to January 2008 were reviewed forthe occurrence of cleft lip and palate. The cleft cases were evaluated for site andtype of cleft and sex of the infant. and some risk factors.Results: 121 cleft lip and/or palate cases out of 60418 live births were registered. T

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Wongsirichat, Nattharin, Basel Mahardawi, Montien Manosudprasit, Aggasit Manosudprasit, and Natthamet Wongsirichat. "The Prevalence of Cleft Lip and Palate and Their Effect on Growth and Development: A Narrative Review." Siriraj Medical Journal 74, no. 11 (2022): 819–27. http://dx.doi.org/10.33192/smj.2022.96.

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Cleft lip and/or cleft palate (CL±P) in addition to the cleft palate (CP) are a category of anomalies known as orofacial clefts (OC). These anomalies are accompanied by several aesthetic and functional problems. Information on the prevalence of OC showed different values between studies worldwide. In addition, the presence of cleft lip and/or cleft palate is determined by several changes during the embryonic stage. Besides, cleft repair may lead to a significant impact on the overall aesthetic and function and could negatively affect maxillary growth on certain occasions. Therefore, having the

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Khatun, Sanzida. "Study of Cleft Lip and Palate in Kathmandu Model Hospital, Nepal." Orthodontic Journal of Nepal 9, no. 1 (2019): 6–10. http://dx.doi.org/10.3126/ojn.v9i1.25682.

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Introduction: Cleft lip and/or palate is a congenitally persistent space affecting orofacial region. It is generally divided into cleft lip (CL), cleft palate (CP) and cleft lip with cleft palate (CLP). The objective of the study was to evaluate distribution of patterns of orofacial clefts according to sex and laterality; predisposing factors and other congenital anomalies associated with cleft lip and/or palate. Materials & Method: A cross-sectional descriptive type of study was carried out using in 268 patients having cleft lip and/or palate. Types of clefts, predominance of sex an

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Emmanuel, JK Adu. "Management of Cleft Lip and Palate: A Five Year Review." Archives of Otolaryngology and Rhinology 3, no. 1 (2017): 023–26. https://doi.org/10.17352/2455-1759.000038.

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<strong>Introduction:</strong> Clefts of the lip may cause cosmetic and social problems. Clefts of the palate may affect feeding, speech and hearing.  <strong>Objective:</strong> To document the clinical and epidemiological features, surgical techniques (Millard’s repair for cleft lip, and the Oxford palatoplasty for cleft palate) and the outcome of treatment of patients with cleft lip and palate at Komfo Anokye Teaching Hospital (KATH), Kumasi, between January 2010 and December 2014. <strong>Patients and Methods:</strong> Data on cleft patients were retrieved from the records of th

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Basavannaiah, Sphoorthi. "Devil’s bite in an adult woman: Unheeded & overlooked." IP Journal of Otorhinolaryngology and Allied Science 5, no. 1 (2022): 21–23. http://dx.doi.org/10.18231/j.ijoas.2022.006.

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Cleft lip and cleft palate are birth defects that occur when a baby’s lip or mouth does not form properly during pregnancy. Together, these birth defects are commonly called “Oro-facial clefts”. Cleft palate alone can often have problems with feed, speech & hearing and problems with teeth development. The causes of these clefts among most infants are unknown. Cleft lip and cleft palate in a child are thought to be caused by a combination of genes and other factors during their gestational development.

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Kilpeläinen, Pauli V. J., Maija T. Laine-Alava, and Seppo Lammi. "Palatal Morphology and Type of Clefting." Cleft Palate-Craniofacial Journal 33, no. 6 (1996): 477–82. http://dx.doi.org/10.1597/1545-1569_1996_033_0477_pmatoc_2.3.co_2.

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In this study, the variation in palatal dimensions, particularly for height, width, and depth, were evaluated in subjects with different types of cleft palate using the moiré technique. The sample consisted of 95 subjects with cleft palate and 68 noncleft individuals. Effects of cleft type, gender, developmental stage of the dentition, missing teeth, and 11 skeletal and pharyngeal cephalometric variables on palatal dimensions were assessed using multiple-regression analyses. The typing of clefts had an effect on the all palatal dimensions. The palate was shallower in subjects with clefts invol

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da Silva Filho, Omar Gabriel, Milton Santamaria, Gisele da Silva Dalben, and Gunvor Semb. "Prevalence of a Simonart's Band in Patients with Complete Cleft Lip and Alveolus and Complete Cleft Lip and Palate." Cleft Palate-Craniofacial Journal 43, no. 4 (2006): 442–45. http://dx.doi.org/10.1597/05-0302.1.

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Objective To investigate the prevalence of the presence of a soft tissue bridge (Simonart's band) in patients with complete cleft lip and alveolus and complete cleft lip and palate. Design Cross-sectional. Sample We assessed 407 consecutive unoperated patients first attending the Hospital for Rehabilitation of Craniofacial Anomalies of University of São Paulo, in Bauru, São Paulo, Brazil, in the year 2000. The patients were classified as presenting complete cleft of the primary palate or of the primary and secondary palate, unilateral or bilateral, as follows: unilateral cleft lip, bilateral c

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Riana A, Ruby. "DISTRIBUSI SUMBING BIBIR DAN LANGIT-LANGIT DI CLEFT LIP AND PALATE CENTER FAKULTAS KEDOKTERAN UNIVERSITAS MUHAMMADIYAH MALANG INDONESIA." Saintika Medika 11, no. 2 (2017): 76. http://dx.doi.org/10.22219/sm.v11i2.4200.

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Objective: The purpose of this study was to investigate the distribution of different cleft pattern by the age of first operation, sex, side of cleft of Cleft Lips (CL), cleft palate (CP) and cleft lip and palate patients (CLP), and education level parents in Cleft Lip and Palate Center in Faculty of Medicine, University of Malang Muhammadiyah (CLPC FM UMM). Study design: Four hundred twenty-nine patients attending the CLPC FM UMM from January 2014 to December 2016 were studied. Most patients came from East Java, Indonesia and the surrounding areas. Result: Highest frequency of CL in CLPC FM U

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Melo Filho, Mario Rodrigues, Verônica Oliveira Dias, Daniella Reis Martelli, et al. "Tooth malposition in patients with cleft lip and/or palate in a Brazilian population." Dentistry 3000 3, no. 1 (2015): 32–37. http://dx.doi.org/10.5195/d3000.2015.38.

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The purpose of the present study was to evaluate the prevalence of teeth malposition (rotated) in Brazilian patients with oral clefts and to contribute to the definition of subphenotypes. This study included 317 patients with nonsyndromic cleft lip with or without cleft palate. Tooth malposition was assessed clinically, through radiographs, and medical history records for each individual. Only teeth malpositions outside the area of the clefts were included. Comparisons were assessed by cross-tabulation and standard chi-square test, and statistical significance was set at p≤0.05. Cleft lip and

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Cooper, Margaret E., Jessica S. Ratay, and Mary L. Marazita. "Asian Oral-Facial Cleft Birth Prevalence." Cleft Palate-Craniofacial Journal 43, no. 5 (2006): 580–89. http://dx.doi.org/10.1597/05-167.

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Objective: To determine the clefting birth prevalence among Asian populations, specifically Chinese and Japanese, using raw counts from nonoverlapping published studies of Asian populations, and to investigate whether Asian clefting rates have been interpreted accurately as being up to twice the Caucasian rate. Design: A literature review of articles giving raw counts of clefting in Asian populations, primarily Japanese and Chinese. Main Outcome Measures: Where possible, clefts were identified by the patients’ ethnicity, country of origin, cleft type, syndromic status, and birth status. Result

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Gregg, Terry, Dorothy Boyd, and Andrew Richardson. "The Incidence of Cleft Lip and Palate in Northern Ireland from 1980–1990." British Journal of Orthodontics 21, no. 4 (1994): 387–92. http://dx.doi.org/10.1179/bjo.21.4.387.

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This study reports the incidence of the various types of cleft lip and/or palate drawn from a regional database of all affected children born in Northern Ireland during the period 1980–1990. The incidence of these anomalies was 1·28 per 1000 live births (1:781). Fifty-three per cent of clefts involved the secondary palate only, 16 per cent the primary palate only, 26 per cent involved both primary and secondary palate, and 5 per cent were unconnected. Overall, more males than females were affected and there were more males than females in the group having complete clefts. Separate clefts of li

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Lohmander-Agerskov, Anette, Ewa Söderpalm, Hans Friede, Eva-Carin Persson, and Jan Lilja. "Pre-Speech in Children with Cleft Lip and Palate or Cleft Palate Only: Phonetic Analysis Related to Morphologic and Functional Factors." Cleft Palate-Craniofacial Journal 31, no. 4 (1994): 271–79. http://dx.doi.org/10.1597/1545-1569_1994_031_0271_psicwc_2.3.co_2.

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Pre-speech in 35 children with clefts of the lip and palate or palate only were analyzed for place and manner of articulation. Transcriptions were made from tape recorded babbling sequences. Two children without clefts were used as reference. All of the children with clefts were treated according to a regimen of early surgical repair of the velum cleft and delayed closure of the cleft in the hard palate. The frequency of selected phonetic features was calculated. Correlations between phonetic/perceptual and functional and morphological factors were tested. Supraglottal articulation dominated a

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Freitas, José Alberto de Souza, Gisele da Silva Dalben, Milton Santamaria Júnior, and Patrícia Zambonato Freitas. "Current data on the characterization of oral clefts in Brazil." Brazilian Oral Research 18, no. 2 (2004): 128–33. http://dx.doi.org/10.1590/s1806-83242004000200007.

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This study aimed at investigating the current distribution of the several types of clefts among the patients receiving treatment at the Hospital for Rehabilitation of Craniofacial Anomalies (HRAC-USP), Bauru, Brazil, for the first time during the year 2000. A total of 803 unoperated patients with cleft lip and/or palate, with or without additional malformations, with no recognizable syndromes, who came to the HRAC-USP for enrollment for treatment during the year 2000. A predominance of complete cleft lip and palate, either unilateral or bilateral, was observed (37.1%), followed by isolated cle

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Demeer, Bénédicte, Nicole Revencu, Raphael Helaers, et al. "Likely Pathogenic Variants in One Third of Non-Syndromic Discontinuous Cleft Lip and Palate Patients." Genes 10, no. 10 (2019): 833. http://dx.doi.org/10.3390/genes10100833.

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Oral clefts are composed of cleft of the lip, cleft of the lip and palate, or cleft of the palate, and they are associated with a wide range of expression and severity. When cleft of the palate is associated with cleft of the lip with preservation of the primary palate, it defines an atypical phenotype called discontinuous cleft. Although this phenotype may represent 5% of clefts of the lip and/or palate (CLP), it is rarely specifically referred to and its pathophysiology is unknown. We conducted whole exome sequencing (WES) and apply a candidate gene approach to non-syndromic discontinuous CL

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Zhu, Wan Chun, Jin Xiao, Yuan Liu, Jun Wu, and JiYao Li. "Caries Experience in Individuals with Cleft Lip and/or Palate in China." Cleft Palate-Craniofacial Journal 47, no. 1 (2010): 43–47. http://dx.doi.org/10.1597/07-076.1.

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Objective To determine the levels of dental caries in subjects with cleft lip and/or palate in China in comparison with controls. Design A total of 380 subjects with cleft lip and/or palate and 339 noncleft control subjects were examined for dental caries using the decayed-missing-filled-teeth (DMFT/dmft) and decayed-missing-filled-surfaces (DMFS/dmfs) index. A questionnaire was used to acquire subjects' living habits and family socioeconomic status. Setting West China Stomatology Hospital, Sichuan University. Subjects Individuals between 3 and 25 years of age. Results Caries prevalence and sc

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Vacher, Christian, Bernard Pavy, and Jeffrey Ascherman. "Musculature of the Soft Palate: Clinico-anatomic Correlations and Therapeutic Implications in the Treatment of Cleft Palates." Cleft Palate-Craniofacial Journal 34, no. 3 (1997): 189–94. http://dx.doi.org/10.1597/1545-1569_1997_034_0189_motspc_2.3.co_2.

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Objective Hypoptasia of the maxilla, often described as a classic sequela to surgical repair of the cleft palate, has been rare In our experience. We believe that our surgical technique, which includes dividing the nasal mucosa and the abnormal muscular insertions at the posterior border of the hard palate, is an important factor in preventing this sequela. Method We compared the anatomy of 12 normal palates in cadavers to the anatomy of cleft palates seen at operation and to the anatomy of one cleft palate in a fetus aged 34 weeks. Results In cleft palates, the muscular fibers have an abnorma

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Mäenpää, Pia, Marja Laasonen, Marja-Leena Haapanen, Joonas Pulkkinen, and Veijo Virsu. "Crossmodal Temporal Processing Acuity in Children with Oral Clefts." Cleft Palate-Craniofacial Journal 45, no. 4 (2008): 393–98. http://dx.doi.org/10.1597/07-050.1.

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Objective: We have previously found that, in children with certain oral clefts, the rate of sequential information processing is significantly impaired in vision and tactile somatosensation but not so clearly in audition. Here, we studied crossmodal functions by investigating temporal processing acuity of cleft children with audiovisual, audiotactile, and visuotactile tasks. Participants: Temporal processing acuity was studied in 10-year-old children, 19 with cleft lip with or without cleft palate and 38 with cleft palate or submucous cleft palate. Design: Children estimated whether brief stim

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Jaruratanasirikul, Somchit, Vichai Chichareon, Nuria Pattanapreechawong, and Pasuree Sangsupavanich. "Cleft Lip and/or Palate: 10 Years Experience at a Pediatric Cleft Center in Southern Thailand." Cleft Palate-Craniofacial Journal 45, no. 6 (2008): 597–602. http://dx.doi.org/10.1597/07-176.1.

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Objective: To study the clinical characteristics, demographic data, and associated congenital anomalies of pediatric patients with cleft lip and/or palate in Southern Thailand. Design: Retrospective, hospital-based study. Setting: Cleft Clinic Center, Songklanagarind Hospital Participants: Children with cleft lip and/or palate who were born or seen at Songklanagarind Hospital between January 1997 and December 2006. Main Outcome Measure: Clinical features including demographic data, types of cleft, associated anomalies, family history of clefts, and physical growth. Results: A total of 153 chil

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Wardhana, Aditya, and Rininta Christabella W. "Orofacial clefts patients epidemiology in Hermina Hospital during 2008-2017." Indonesia Journal of Biomedical Science 18, no. 1 (2024): 41–44. http://dx.doi.org/10.15562/ijbs.v18i1.533.

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Background: Malformation of lip and palate closure that occurs during embryology time in the mother's womb will affect the shape of mouth and face. This congenital malformation is often referred to orofacial clefts including cleft lip, cleft palate, cleft lip and palate. Orofacial clefts cases are still commonly found in Indonesia. This study aims to present orofacial clefts patients epidemiology in Hermina Hospital during 2008-2017. Methods: Retrospective studies were conducted on 230 orofacial clefts patients at Hermina Podomoro and Hermina Kemayoran Hospital from 2008 until 2017. The variab

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Vieira, A. R., I. M. Orioli, E. E. Castilla, M. E. Cooper, M. L. Marazita, and J. C. Murray. "MSX1 and TGFB3 Contribute to Clefting in South America." Journal of Dental Research 82, no. 4 (2003): 289–92. http://dx.doi.org/10.1177/154405910308200409.

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MSX1 and TGFB3 have been proposed as genes in which mutations may contribute to non-syndromic forms of oral clefts; however, an interaction between these genes has not been described. The present study attempts to detect transmission distortion of MSX1 and TGFB3 in 217 South American children from their respective mothers. With transmission disequilibrium test analysis, cleft lip with/without cleft palate, cleft lip with palate plus cleft palate only, and all datasets combined showed evidence of association with MSX1 (p = 0.004, p = 0.037, and p = 0.001, respectively). With likelihood ratio te

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Al-Fahdawi, Mahmood Abd, Mary Medhat Farid, Mona Abou El-Fotouh, and Marwa Abdelwahab El-Kassaby. "Cone-Beam Computed Tomography Analysis of the Nasopharyngeal Airway in Nonsyndromic Cleft Lip and Palate Subjects." Cleft Palate-Craniofacial Journal 54, no. 2 (2017): 202–9. http://dx.doi.org/10.1597/15-134.

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Objective To assess the nasopharyngeal airway volume, cross-sectional area, and depth in previously repaired nonsyndromic unilateral cleft lip and palate versus bilateral cleft lip and palate patients compared with noncleft controls using cone-beam computed tomography with the ultimate goal of finding whether cleft lip and palate patients are more liable to nasopharyngeal airway obstruction. Design A retrospective analysis comparing bilateral cleft lip and palate, unilateral cleft lip and palate, and control subjects. Significance at P ≤ .05. Setting Cleft Care Center and the outpatient clinic

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Behal, Roobal, Asif Khan, and Ashok Utreja. "Psychological Implications in Parents of Cleft Lip and Palate Children." Dental Journal of Advance Studies 04, no. 01 (2016): 015–17. http://dx.doi.org/10.1055/s-0038-1672039.

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Abstract Objective: To determine quality of life of parents of children with cleft lip and palate and to compare it with parents of non cleft lip and palate children. Method: World Health Organisation Quality of Life (Bref, Field Trial version,1996) for parents of children with cleft lip and palate. Total of 40 parents were questioned, 20 were parents of CLP chidren and the other 20 were parents of non cleft children. Results: The scores of quality of life for parents of the cleft children were significantly lower than the parents of non-cleft children. Conclusion: The parents of children with

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Mitic, Vladimir, Marina Jonovic, Nadica Mitic, et al. "Incidence of lip and palate clefts in children in Nis from 1990 to 2007." Srpski arhiv za celokupno lekarstvo 139, no. 5-6 (2011): 298–303. http://dx.doi.org/10.2298/sarh1106298m.

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Introduction. Cleft lip and palate is a complex congenital anomaly of the orofacial system in children. Objective. The aim of this study was to determine the incidence of live-born children with cleft lip and/or palate compared to the total number of children born in the period from January 1, 1990 to December 31, 2007. Methods. Epidemiological investigation was based on the records of live-born children at the Hospital of Gynaecology and Obstetrics of the Clinical Centre Nis. The study included 61,116 live-born children, i.e. 56,905 full-term babies. Results. The total number of registered cl

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Onofre, Mirian Aparecida, Heli Benedito Brosco, and Rumio Taga. "Relationship between Lower-Lip Fistulae and Cleft Lip and/or Palate in Van der Woude Syndrome." Cleft Palate-Craniofacial Journal 34, no. 3 (1997): 261–65. http://dx.doi.org/10.1597/1545-1569_1997_034_0261_rbllfa_2.3.co_2.

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Objective This study was conducted to evaluate the relationship between fistulae of the lower lip and cleft lip and/or palate in patients with Van der Woude syndrome. Methods The medical records of 11,000 patients with cleft lip and/or palate registered at the Cleft Lip-Palate Research and Rehabilitation Hospital, University of São Paulo, Bauru were reviewed. Of these patients, 133 (1.2%) presented with Van der Woude syndrome. Results Of the 133 patients, 88 (66.2%) exhibited full clefts, 22 (16.5%) only cleft lip, and 23 (17.3%) only cleft palate. The lower-lip fistulae observed in these 133

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Kim, Seong Sik. "Orthodontic treatment and management of adult patient with cleft lip and palate." Journal of The Korean Dental Association 53, no. 7 (2015): 457–67. http://dx.doi.org/10.22974/jkda.2015.53.7.002.

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Patients with cleft lip and palate require interdisciplinary treatment to achieve successful rehabilitation. However, there are special difficulties in orthodontic treatment of adult cleft lip and palate patients: 1. Lack of Tissue, Bone, and Soft tissue; 2. Heavy Scar Tissue, Vestibule, and Palate; 3. Severe Anteroposterior discrepancy and Impaired Maxilla; 4. Distortion of Alveolar Ridge; 5. Abnormal Eruption Path and Malalignment of Tooth. Solving these problems, orthodontist should have differential diagnosis on extent of cleft site and residual deformities of adult cleft lip and palate pa

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Šmahel, Zbyněk, and Božena Škvařilová. "Length of the Cervical Spine as a Factor in the Etiology of Cleft Palate." Cleft Palate-Craniofacial Journal 30, no. 3 (1993): 274–78. http://dx.doi.org/10.1597/1545-1569_1993_030_0274_lotcsa_2.3.co_2.

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The length of the cervical spine in a series of 206 adult males with cleft lip and/or palate and 50 normal controls was measured. The patients were divided into five subgroups according to the type and extent of the cleft. The shortening of the spine was most marked in bilateral cleft lip and palate patients (complete), less marked in unilateral cleft lip and palate patients, and was slight in isolated cleft palate patients. Complete isolated cleft palate and cleft lip was not associated with a shortening of the spine. A shortening of the cervical spine in less extensive types of isolated clef

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Al Omari, F., and I. K. Al-Omari. "Cleft Lip and Palate in Jordan: Birth Prevalence Rate." Cleft Palate-Craniofacial Journal 41, no. 6 (2004): 609–12. http://dx.doi.org/10.1597/03-034.1.

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Objective and Design A retrospective investigation was conducted to determine the prevalence rate of Jordanian children born with oral clefts from 1991 to 2001. Setting Hospital surgical records from two main sources were used to identify all children born with orofacial clefting. Information about date of birth, sex, cleft types, and associated major anomalies and syndromes were recorded. Results The overall prevalence rate for live births with cleft lip, cleft palate, or both was 1.39 per 1000 live births. Thirty percent of the clefts identified affected the lip, 22 percent affected the pala

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Alves, Karina Mirela Ribeiro Pinto, Virginia Peixoto, Márcia Ribeiro Gomide, Cleide Felíciode Carvalho Carrara, and Beatriz Costa. "Prevalence of Palatal and Alveolar Cysts in Babies with Cleft Lip and Palate." Cleft Palate-Craniofacial Journal 41, no. 5 (2004): 490–93. http://dx.doi.org/10.1597/02-139.1.

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Objective To evaluate the prevalence of palatal and alveolar cysts in babies with cleft lip and/or palate. Design Cross-sectional. Setting Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo (HRAC-USP), Bauru, São Paulo, Brazil. Participants Two hundred ninety-one Caucasian babies divided into four groups according to the type of cleft: cleft lip with or without cleft alveolus (70), complete unilateral cleft lip and palate (112), complete bilateral cleft lip and palate (56), and cleft palate (53). Results A low prevalence of palatal and alveolar cysts was observed am

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Chandrasekharan, Deepak, and Arvind Ramanathan. "Identification of a novel heterozygous truncation mutation in exon 1 of ARHGAP29 in an Indian subject with nonsyndromic cleft lip with cleft palate." European Journal of Dentistry 08, no. 04 (2014): 528–32. http://dx.doi.org/10.4103/1305-7456.143637.

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ABSTRACT Objective: Mutations in exon 1 of ARHGAP29, a RhoA specific GTPase have been identified in North American and Filipino subjects with nonsyndromic cleft palate and cleft lip with or without cleft palate. Since the genetic status of ARHGAP29 in Indian subjects with nonsyndromic oral clefts is not known, we designed the present study to investigate the occurrence of the above mutations in them. Materials and Methods: Total genomic DNA extracted from peripheral blood of 60 subjects with nonsyndromic cleft palate and cleft lip with or without cleft palate, and equal number of control healt

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Bamborschke, Daniel, Matthias Pergande, Hülya Sevcan Daimagüler, et al. "Cleft Palate as Distinguishing Feature in a Patient with GABRB3 Epileptic Encephalopathy." Neuropediatrics 50, no. 06 (2019): 378–81. http://dx.doi.org/10.1055/s-0039-1693143.

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Mutations in GABAA-receptor subunit genes are associated with a heterogeneous spectrum of epilepsies. Patients with epilepsy caused by mutations in a specific GABAA-receptor (GABRA3) occasionally present with orofacial dysmorphism (e.g., cleft palates). While cleft palates have been described in Gabrb3 knockout mice and in humans with GABRB3 variants without epilepsy, the specific combination of epilepsy and cleft palate in humans with GABRB3 mutations has not yet been reported.We describe a patient with epileptic encephalopathy (EE) who presented with therapy-refractory neonatal-onset myoclon

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Kanth, Aditi M., Max Krevalin, and Oluwaseun A. Adetayo. "Surgical Approach to Hemipalatal Discrepancy in Tessier 7 Reconstruction: Review of Literature and Case Series." Cleft Palate-Craniofacial Journal 58, no. 9 (2021): 1094–101. http://dx.doi.org/10.1177/1055665620984045.

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Objective: The authors present findings and techniques to address hemipalatal discrepancy in patients with Tessier 7 cleft and associated cleft palate during cleft palatoplasty. Design: The authors report 2 cases of pediatric patients with Tessier 7 facial clefts and associated cleft palate. One patient presents on the broader oculo-auriculo-vertebral spectrum and the other is has isolated Tessier cleft 7. Additionally, a PubMed search was performed using the MeSH terms “tessier 7,” “cleft palate”, “macrostomia,” “tessier 7 AND cleft palate,” “macrostomia AND cleft palate,” AND “hemipalatal di

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Sivesh Sangar, Vignesh Ravindran, and Visalakshi Ramanathan. "Dental Caries in Children With and Without Cleft Palate: A case Control Study." International Journal of Research in Pharmaceutical Sciences 11, SPL3 (2020): 1494–99. http://dx.doi.org/10.26452/ijrps.v11ispl3.3459.

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The lack of knowledge about oral hygiene maintenance among the general population with oro-facial clefts would lead to a poororal health. The aim was to determine the prevalence of dental caries status in children with cleft palate only. The purpose of the study was to assess the prevalence of dental caries status in children with cleft palate only. A study was carried out by collecting data by reviewing patients’ data and analysing the data of 86000 patients between June 2019 and March 2020 at the private dental institute. The sample size that was taken included 19 children with cleft palate

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Watanabe, Akira, Sadanori Akita, Nguyen Thi Duc Tin, et al. "A Mutation in RYK is a Genetic Factor for Nonsyndromic Cleft Lip and Palate." Cleft Palate-Craniofacial Journal 43, no. 3 (2006): 310–16. http://dx.doi.org/10.1597/04-145.1.

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Objective The RYK, EPHB2, and EPHB3 genes are attractive candidates for cleft lip and/or palate and cleft palate only pathogenesis. Both the Ryk-deficient mouse and Ephb2/Ephb3 (genes for interaction molecules with RYK) double-mutant mouse show cleft palate. Setting Mutation searches for RYK, EPHB2, and EPHB3 were carried out in a large number of Japanese and Vietnamese patients with cleft lip and/or palate and cleft palate only. Case-control study and transmission disequilibrium tests were performed also, using three single nucleotide polymorphisms within a linkage disequilibrium block in RYK

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Suslak, Lorraine, and Franklin Desposito. "Infants with Cleft Lip/Cleft Palate." Pediatrics In Review 9, no. 10 (1988): 331–34. http://dx.doi.org/10.1542/pir.9.10.331.

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A cleft of the lip and/or palate occurs approximately once in 750 live births with some variability among various racial groups. As an isolated defect, cleft lip with or without cleft palate is etiologically distinct from cleft palate alone. More than 250 clefting syndromes, most of them relatively uncommon, have been described. In 1970, less than 3% of all cases of cleft lip and/or palate were thought to be associated with identifiable syndromes. A recent survey from a major cleft palate center in New York showed that 30% of patients had recognizable conditions. Some of these included genetic

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Jones, Courtney E., Kathy L. Chapman, and Mary A. Hardin-Jones. "Speech Development of Children with Cleft Palate before and after Palatal Surgery." Cleft Palate-Craniofacial Journal 40, no. 1 (2003): 19–31. http://dx.doi.org/10.1597/1545-1569_2003_040_0019_sdocwc_2.0.co_2.

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Objective This study examined the speech production abilities of children with cleft palate before and after palate repair. Participants Twenty-eight children participated in the study, 14 with cleft palate and 14 without clefts matched for age, gender, and mothers’ educational level. Main Outcome Measures Comparisons were made between the children with cleft palate before and after surgery for canonical babbling ratios, size of consonant inventories, place and manner characteristics, and early developing sounds [p, b, t, d, k, g, m, n, η]. Also, comparisons were made between the children with

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