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1

Devlieger, R. "Uterine adenomyosis in the infertility clinic." Human Reproduction Update 9, no. 2 (2003): 139–47. http://dx.doi.org/10.1093/humupd/dmg010.

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2

Raimondo, Diego, Lucia Lazzeri, Antonio Raffone, et al. "Sonographic Assessment of Uterine Biometry for the Diagnosis of Diffuse Adenomyosis in a Tertiary Outpatient Clinic." Journal of Personalized Medicine 12, no. 10 (2022): 1572. http://dx.doi.org/10.3390/jpm12101572.

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Background: to compare several uterine biometric parameters at transvaginal ultrasound (TVUS) between adenomyosis and non-adenomyosis uteri and evaluate their role for the diagnosis of diffuse adenomyosis. Methods: prospective observational study conducted between the 1 February 2022 and the 30 April 2022. In this case, 56 patients with TVUS diagnosis of adenomyosis were included. A 1:1 ratio age and parity-matched group of non-adenomyosis patients was selected. We compared sonographic uterine biometric parameters (longitudinal (LD), anteroposterior (APD) and transverse (TD) diameters, volume,
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Abdurakhmanova, S.I., and M.M. Rizaeva. "ANALYSIS OF THE GROWTH OF COMPLICATIONS OF UTERINE FIBROIDS AND ADENOMYOSIS IN POSTCOVID WOMEN." Journal of reproductive health and uro-nephrology research 3, no. 4 (2022): 4. https://doi.org/10.5281/zenodo.7418205.

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In gynecology, the most common diseases include uterine fibroids and adenomyosis. We can observe a significant increase in the detection of uterine fibroids and adenomyosis and their complications after the coronavirus pandemic. The study was conducted in the gynecology department of the III multidisciplinary clinic of TMA for the period 2018 – 2022, the medical histories of patients admitted to inpatient treatment for uterine fibroids and adenomyosis were studied.  
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Biasioli, Anna, Matilde Degano, Stefano Restaino, et al. "Innovative Ultrasound Criteria for the Diagnosis of Adenomyosis and Correlation with Symptoms: A Retrospective Re-Evaluation." Biomedicines 12, no. 2 (2024): 463. http://dx.doi.org/10.3390/biomedicines12020463.

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The 2022 Delphi revision of the MUSA (Morphological Uterus Sonographic Assessment) criteria for the ultrasound diagnosis of adenomyosis divides the ultrasound signs for diagnosis into direct and indirect ones, considering the presence of at least one direct sign as a mandatory criterion. This study aimed to reclassify the patients referred to the Pelvic Pain specialist outpatient clinic of the Gynecological Clinic of Udine according to the new criteria, evaluating the number of overdiagnoses and the possible correlation between the direct and indirect signs and the patients’ symptoms. 62 patie
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5

Stewart, Chelsea E., Mario E. Castellanos, Samantha P. Nadella, Rachel Eliason, Pooja Doehrman, and Ashley Gubbels. "Prevalence of histologically confirmed adenomyosis in a chronic pelvic pain cohort." Journal of Endometriosis and Pelvic Pain Disorders 15, no. 2 (2023): 58–63. http://dx.doi.org/10.1177/22840265231180676.

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Introduction: We aimed to determine the prevalence of pathology confirmed adenomyosis in women with chronic pelvic pain (CPP) who underwent surgical management with total hysterectomy, and to identify associated risk factors and demographic variables. Methods: This is a retrospective cohort study involving 1186 patients treated in a CPP-specialty clinic who underwent surgical management with hysterectomy between January 2010 and December 2021. Results: About 532/1186 (44.9%) of the cohort were diagnosed with adenomyosis on pathology following total hysterectomy. The average age of patients wit
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6

Yaramareddy, Swapna, Siyonu Kumari Sardena, Nom Kumar Naik Bhukya, and Tulasi Ram Naik Menavath. "Fertility sparing treatment in an infertile patient with severe adenomyosis and a uterine fibroid: a case report." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 12, no. 5 (2023): 1510–12. http://dx.doi.org/10.18203/2320-1770.ijrcog20231254.

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Adenomyosis and uterine leiomyoma are benign lesions of the myometrium. Adenomyosis is a myometrial lesion characterised by the presence of ectopic endometrium with or without hyperplasia of the surrounding myometrium. Uterine fibroids, also called leiomyomas or myomas, are benign tumours that arise from the smooth muscle of the uterus. A 33-year-old nulliparous woman attended the clinic with primary infertility for 18 years. She was diagnosed with severe adenomyosis and uterine fibroids. She conceived successfully after undergoing in vitro fertilization (IVF) and a downregulated frozen embryo
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7

Usta, Taner A., Tolga Karacan, Ulviye Hanli, Elif Cansu, and Engin Oral. "Hysteroscopic management of a juvenile cystic adenomyosis." Journal of Endometriosis and Pelvic Pain Disorders 10, no. 2 (2018): 123. http://dx.doi.org/10.1177/2284026518778793.

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Introduction: Hysteroscopic management of juvenile cystic adenomyosis on a virgin patient with non-touch technique. Description: Juvenile cystic adenomyosis of uterus is a cyst which is surrounded by myometrium and inside of this cyst is filled with hemorrhagic fluid. A 23-year-old virgin patient admitted to endometriosis outpatient clinic. The patient complained of dysmenorrhea, chronic pelvic pain, and abnormal uterine bleeding. A submucosal adenomyotic cyst was, sized 40 mm approximately, determined at posterior wall of uterus by transrectal ultrasonography. She received daily 2 mg dienoges
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8

Prudnikov, P. M. "Role of clinical-anamnestic data in adenomyosis development at the present stage." HEALTH OF WOMAN, no. 4(120) (May 30, 2017): 54–56. http://dx.doi.org/10.15574/hw.2017.120.54.

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The objective: to study a role of clinical-anamnestic data in development and an adenomyosis current at the present stage. Patients and methods. Еxamination of 110 patients, from which 60 – patients with an adenomyosis of different degree of activity and prevalence – the main group was conducted. Depending on degree of expression of the main clinical implications, characteristic for the adenomyosis, all studied patients with an adenomyosis (n=60) conditionally were divided into 2 clinical subgroups: 1.1 – the subgroup was made by 38 patients with clinically "active" adenomyosis; 1.2 a subgroup
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9

Sendetskiy, Serhij. "Clinical­and­anamnestic features of adenomyosis and combined pathology of uterus." Perinatology and reproductology: from research to practice 4, no. 4-1 (2025): 89–94. https://doi.org/10.52705/2788-6190-2024-04.1-13.

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The objective: to learn a role of clinical-and-anamnestic information in development and motion of adenomyosis on the modern stage.Materials and methods. An inspection was conducted 110 patients. A basic group was made by 60 patients, patients on adenomyosis of different degree of activity and prevalence. Depending on the degree of expressed of basic clinical displays, characteristic for adenomyosis, all investigational patients from adenomyosis (n=60) de bene esse parted on two clinical sub-groups: 1.1 – 38 patients from clinically «active» adenomyosis; 1.2 – 22 patients from clinically «nona
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10

Leshchova, Olga. "The women of the different age­related groups have clinical aspects of adenomyosis." Perinatology and reproductology: from research to practice 4, no. 2 (2024): 64–69. https://doi.org/10.52705/2788-6190-2024-02-10.

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The objective: study of modern clinical aspects of adenomyosis. Materials and methods. An inspection was conducted 170 patients, from what 120 are patients of adenomyosis of different degree of activity and prevalence - basic group. A control group was made by 50 patients reproductive and premenopausal age without adenomyosis, which was added hysteгectomy with subsequent pathomorphological research of body of uterus concerning pelvic organ prolapse. To the complex of methods of researches were included clinical, laboratory, instrumental, morphological and statistical. Results. As a result of a
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11

Zhang, Yiqun, Lu Xue, Chunlian Zhang, and Jianying Zhou. "Evaluation of the Application Effect of Contrast-Enhanced Ultrasound Image Technology Based on Three-Dimensional Image Fusion Algorithm in the Diagnosis of Adenomyosis." Scientific Programming 2021 (August 28, 2021): 1–6. http://dx.doi.org/10.1155/2021/2896752.

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In this paper, the effect of ultrasound images based on a 3-dimensional image fusion algorithm in the diagnosis of adenomyosis was evaluated. 88 patients with adenomyosis who were treated in the hospital from February 2019 to May 2020 were selected as the research subjects. They were rolled into localized type (Group A), with 40 cases, and diffuse type (Group B), with 48 cases. At the same time, 45 women of normal childbearing age who underwent physical examination in the outpatient clinic were rolled into the control group (Group C). Three-dimensional ultrasound scans of the uterus were perfo
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12

Kadam, Nikit, Somia Khalid, and Kanna Jayaprakasan. "How Reproducible Are the Ultrasound Features of Adenomyosis Defined by the Revised MUSA Consensus?" Journal of Clinical Medicine 14, no. 2 (2025): 456. https://doi.org/10.3390/jcm14020456.

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Background/Objectives: The aim of this study is to assess the inter- and intra-observer reproducibility of the identification of direct and indirect ultrasonographic features of adenomyosis as defined by the revised Morphological Uterus Sonographic Assessment (MUSA) consensus (2022). Methods: A cohort of 74 women, aged 18 to 45, were recruited from the recurrent miscarriage and general gynaecology clinic at a university-based fertility centre. All the participants underwent 2D and 3D transvaginal Ultrasound scan (TVS) examination in the late follicular and early luteal phase. Conventional grey
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13

Du, Xiaoxin, Zhihui Cai, and Liwei Yan. "Current Status of the Diagnosis and Treatment of Adenomyosis." International Journal of General Practice Nursing 2, no. 2 (2024): 20–26. http://dx.doi.org/10.26689/ijgpn.v2i2.7249.

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Adenomyosis refers to the endometrial glands and mesenchyme that invade the myometrium through the basal layer, and under the action of hormones, repeated bleeding, myofibrous connective tissue hyperplasia formed by diffuse or limited lesions. It is a common disease in women of childbearing age and is more common in women over 40 years of age with menstruation. In recent years, the age of onset of the disease tends to be younger, which may be related to the various uterine surgical operations in clinical work, such as abortion, childbirth, curettage, chronic endometritis, and so on. The mechan
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14

Akdan, Enes, Neşe Yücel, and Fikriye Işıl Adıgüzel. "The frequency of structural causes (PALM) according to FIGO PALM-COEIN classification in patients undergoing hysterectomy for abnormal uterine bleeding." Journal of Medicine and Palliative Care 5, no. 3 (2024): 172–76. http://dx.doi.org/10.47582/jompac.1483113.

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Aims: We aimed to determine the frequency of the PALM group in the FIGO PALM-COEIN system of patients who were operated for AUB, and to evaluate and analyze our data in our clinic. Methods: In a retrospective study, data were obtained for nonpregnant women aged 18–55 years who underwent hysterectomy for AUB at a center in Turkey in 2017-2022. The patients were retrospectively classified according to the PALM-COEIN system. Results: A total of 847 women were included. Leiomyoma was the most common pathology result in only 377 (44.5%) patients. The second most common pathology result was adenomyo
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15

Ahkubekova, Nelly K., Anatoly T. Tereshin, and Angela E. Bestaeva. "Correction of psychoemotional and vascular-autonomic dysfunction with patients suffering from endometrial disease under the influence of complex radon, laser, and drug treatment." Russian Journal of Physiotherapy, Balneology and Rehabilitation 18, no. 3 (2021): 161–65. http://dx.doi.org/10.17816/1681-3456-2019-18-3-161-165.

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The research objective is to develop a program to correct psycho-emotional and vascular-autonomic dysfunction with patients suffering from adenomyosis using complex radon, laser and drug treatment.
 Material and methods. There were 100 women with adenomyosis complicated by psycho-emotional and vascular-autonomic dysfunction from the age of 23 up to 37 years old who underwent treatment at a branch of Pyatigorsk Clinic of North Caucasian Federal Scientific and Clinical Centre of Federal Medical and Biological Agency of Russia. The patients were divided into 2 groups by a randomized method:
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16

Likhacheva, V. V., A. G. Markdorf, L. G. Bazhenova, A. E. Vlasenko, and S. V. Shramko. "Evaluation of the influence of clinical risk factors on the performance of extracorporal fertilization programs." Bulletin of Siberian Medicine 17, no. 2 (2018): 49–59. http://dx.doi.org/10.20538/1682-0363-2018-2-49-59.

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Purpose of the study. To assess the influence of main clinical risk factors on the effectiveness of the in vitro fertilization (IVF) program.Materials and methods. The study included 3,969 IVF programs conducted in the “Medica” clinic of the “Mother and Child” group of companies in Novokuznetsk for 2010–2015. The inclusion criterion was the availability of information on the results of the procedure conducted.Results.The structure of the considered risk factors was identified, their key features were identified: the majority of women who underwent IVF procedure were under the age of 34, inclus
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17

Uema, Cecilia Raquel L. M., André Luiz Mota da Costa, and Stefanie Vanessa Santos. "Cystic endometrial hyperplasia in african pygmy hedgehog (Atelerix albiventris) – case report." Clínica Veterinária XXV, no. 146 (2020): 52–60. http://dx.doi.org/10.46958/rcv.2020.xxv.n.146.p.52-60.

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A 2 year old female african pygmy hedgehog (Atelerix albiventris) was presented at a private clinic with persistent hematuria. Abdominal ultrasound identified suggestive changes of uterus enlargement, indicating its surgical removal. Anesthesia was accomplished with isoflurane via chamber induction and was maintained via mask. Ovariohysterectomy was performed and tissue fragments were submitted to histopathologic evaluation. For postoperative treatment, meloxicam, enrofloxacin and dipyrone were used. Microscopy revealed moderate uterine squamous metaplasia, cystic endometrial pseudocarcinomato
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18

М., Б. Запорожченко, В. Сидоренко А., and Ю. Парубина Д. "Concomitant endometriosis and leiomyoma in women of reproductive age." REPRODUCTIVE ENDOCRINOLOGY, no. 36 (September 14, 2017): 24–30. https://doi.org/10.18370/2309-4117.2017.36.24-30.

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Endometriosis and leiomyoma commonly co-exist inside one uterus. Specialized surgical centers report detection frequency of comorbid endometriosis during surgery or laparoscopy that varies from 20 to 87% in patients with symptomatic fibroids. In authors practice the histological study of surgery samples from patients diagnosed with symptomatic fibroids (113 hysterectomies) revealed concomitant endometriosis in 26.5% cases. Clinical and morphological analysis showed that in patients with multiply fibroids, large volumes or submucous myomas comorbid adenomyosis doesn’t interfere significan
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19

Н., Ф. Захаренко, В. Коваленко Н. та П. Маноляк И. "Clinical case report: сonservative treatment of nodular adenomyosis". Reproductive Endocrinology, № 40 (30 квітня 2018): 44–48. https://doi.org/10.18370/2309-4117.2018.40.44-48.

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The article describes the clinical case of the nodular form of adenomyosis, first detected in a patient at the age of 16 years after another appeal to a gynecologist in connection with pronounced prolonged dysmenorrhea with ultrasound of a small pelvis. After the diagnosis of “Nodular form of adenomyosis”, the patient received 6 injections of triptorelin acetate 3.62 mg, resulting in an adenomyosis node decreased in size from 72 x 68 mm to 31 x 29 mm. Taking into account the developed side effects (aches in bones, hot flushes, weakness, tachycardia), therapy with triptorelin was di
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Naftalin, J., W. Hoo, K. Pateman, D. Mavrelos, T. Holland, and D. Jurkovic. "How common is adenomyosis? A prospective study of prevalence using transvaginal ultrasound in a gynaecology clinic." Human Reproduction 27, no. 12 (2012): 3432–39. http://dx.doi.org/10.1093/humrep/des332.

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21

Kandyba, L. I., I. M. Sykal, V. M. Olkhovska, and M. P. Sokol. "ISTHMOCELE: ETIOLOGY, CLINIC, DIAGNOSIS AND TREATMENT (Literature review)." International Medical Journal, no. 1 (February 14, 2021): 52–55. http://dx.doi.org/10.37436/2308-5274-2021-1-9.

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Modern obstetrics is characterized with a loyal approach to surgical delivery, which has significantly affected the activity of maternity hospitals: the number of complications in childbirth from both the mother and fetus has decreased. The formed scar on the uterus is determined differently when examining the women in the postoperative period. Isthmocele is a hypogenic area in the myometrium within the site of postoperative scar in the form of a "niche", diverticulum or sac after cesarean section. It can lead to the development of diseases: abnormal uterine bleeding, dysmenorrhea, chronic pel
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Budak, Hıdır, Rezan Buğday, Mehmet Şükrü Budak, Ahmet Yalınkaya, Adnan Budak, and Talip Gül. "Pre- and Postoperative Evaluation of Operated Myoma Uteri Patients: a 5-Year Tertiary Care Experience." Aegean Journal of Obstetrics and Gynecology 1, no. 1 (2019): 8–12. http://dx.doi.org/10.46328/aejog.v1i1.12.

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Introduction: This study aims to evaluate the pre- and postoperative outcomes of myomas operated in a tertiary clinic.
 Method: We retrospectively evaluated data from a total of 378 cases operated for myomas between January 2014 and December 2018 in the Dicle University Medical Faculty Obstetrics and Gynecology Clinic. 
 Results: There were 169 cases of abdominal myomectomy (44.7%), 156 cases of total abdominal hysterectomy (41.3%), 15 cases of laparoscopic myomectomy (4%), 13 cases of total laparoscopic hysterectomy (3.4%), 12 cases of myomectomy during cesarean delivery (3.2%), 9 c
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Khodjaeva, Zarina Alikhanovna, and Djuraevna Muratova Nigora. "Features of clinical and laboratory parameters of adenomyosis combined with endometrioid ovarian cysts." Journal of reproductive health and uro-nephrology research 3, no. 4 (2022): 4. https://doi.org/10.5281/zenodo.7420829.

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The most common diseases among women of reproductive age include fibroids, adenomyosis and endometrioid ovarian cysts. The aim of the study was to determine the clinical and laboratory parameters of adenomyosis combined with endometrioid ovarian cysts in young women. We examined 80 women of reproductive age with adenomyosis and endometriosis of the ovaries. The average age of the examined patients was 25.4±0.14 years. All patients underwent hormonal, ultrasound and Doppler methods of examination. The results of the studies showed that 70% of the examined patients reported bleeding from
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Morelli, Michele, Roberta Venturella, Rita Mocciaro, Daniela Lico, and Fulvio Zullo. "An Unusual Extremely Distant Noncommunicating Uterine Horn with Myoma and Adenomyosis Treated with Laparoscopic Hemihysterectomy." Case Reports in Obstetrics and Gynecology 2013 (2013): 1–3. http://dx.doi.org/10.1155/2013/160291.

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A 41-year-old woman referred to us with dysmenorrhea and severe pelvic pain although she was previously submitted to right laparotomic adnexectomy for ovarian endometrioma and to a subsequent operative laparoscopy for pelvic adhesions. After ultrasound examination, the patient underwent diagnostic hysteroscopy and operative laparoscopy which confirmed the clinic suspect of an unicornuate uterus. However, it was very unusual to see an extremely distanced right horn, without communication with uterus, without adnexa, and with a small myoma belonging to it. Moreover, omentum and bowel were attach
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Dr., Nida Fatima Dr. Israr Khan Dr. Hafsa Liaqat. "PATHOLOGICAL AND CLINICAL FACTORS LEADING TO HYSTERECTOMIES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 05 (2018): 4620–24. https://doi.org/10.5281/zenodo.1257658.

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<strong><em>Objective</em></strong><em>: To evaluate the pattern and frequency of </em><em>premalignant, malignant and benign lesions in </em><em>hystrectomized uteri and execute clinic-pathological investigation.</em> <strong><em>SETTING: </em></strong><em>collection of various </em><em>hysterectomy samples from </em><em>Nishtar Hospital Multan</em><em> was carried out. These specimens were studied in the </em><em>histopathology departments of these medical universities. Duration of the study was from </em><em>January</em><em> 2016 to December 2017.</em> <strong><em>Methods:</em></strong><em>
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Chermak, Ihor I., Volodymyr I. Chermak, Roman M. Zakordonets, Olori Sharon Oboghene, and Anatolii Ya Senchuk. "New approaches to the treatment of endometrial pathology in patients with extragenital diseases." Biomedical update, no. 2 (November 24, 2021): 22–27. http://dx.doi.org/10.52739/bio-up.2.2021.22-27.

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With purpose to increase efficiency and decrease frequencies of complications after treatment of endo- and myometrium pathology in patients of the perimenopausal period with extragenital pathology this study has been conducted. Different conducted clinic-laboratory, instrumental and pathology examination were performed. 130 patients of the perimenopausal period from somatic pathology (46-60 years) were divided into representative groups. The main group consisted of 100 patients who suffered from endometrium hyperplasia and adenomyosis. The control group included 30 healthy women without pathol
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Gkrozou, Fani, Anastasia Vatopoulou, Chara Skentou, and Minas Paschopoulos. "Diagnosis and Treatment of Adenomyosis with Office Hysteroscopy—A Narrative Review of Literature." Diagnostics 13, no. 13 (2023): 2182. http://dx.doi.org/10.3390/diagnostics13132182.

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Introduction: Adenomyosis is a common chronic disease in women of reproductive age, characterised by the presence of ectopic endometrial tissue within myometrium. Even though adenomyosis presents with chronic pelvic pain, menorrhagia or abnormal uterine bleeding, dysmenorrhoea, and dyspareunia and is often recognised after hysterectomies. However, the development of ultrasonography and magnetic resonance imaging has improved the pre-operative diagnosis of the disease. Hysteroscopy provides information in real time from the uterine cavity and the offers the possibility of obtaining direct biops
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Marhenriyanto, Wahyuridistia, and Dedy Hendry. "Perbandingan Skala Nyeri Pasien Kista Endometriosis Dan Adenomiosis Sebelum Operasi, Setelah Operasi Dan Setelah Pemberian GNRH Analog." JOURNAL OBGIN EMAS 4, no. 1 (2020): 35–47. http://dx.doi.org/10.25077/aoj.4.1.35-47.2020.

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Background: Endometriosis is the growth of the epithelium and endometrial glands outside the uterine cavity. In endometriosis there is a process of neurogenesis and angiogenesis. The degree of endometriosis pain depends on the depth of endometrial implant infiltration in nerve fibers and / or neurogenesis. Operative action and postoperative hormone therapy are the main choices for preventing recurrence and reducing pain complaints.Purpose: to determine the comparison of pain scales of patients with endometriosis before surgery, after surgery and after administration of GnRH analogues.Method: T
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Rusda, Muhammad, Andri Sipahutar, and Andrina Yunita Murni Rambe. "Application of International Endometrial Tumor Analysis in Abnormal Uterine Bleeding: A Case Report." Open Access Macedonian Journal of Medical Sciences 10, T7 (2022): 7–11. http://dx.doi.org/10.3889/oamjms.2022.9236.

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BACKGROUND: Abnormal uterine bleeding (AUB) is one of the clinical symptoms found in malignant conditions where the incidence of newly diagnosed cancers reached 100,000 cases in Europe in 2012 with an incidence of around 14.7/100,000 women. The International Endometrial Tumor Analysis (IETA) group, formed in Chicago in 2008, published a consensus stating how to examine and measure the endometrium. CASE REPORT: Mrs. M, 49 years old, came to Gynecology Clinic of USU Hospital on February 22, 2021, at 13.00 WIB with the complaints of prolonged menstruation for 2 months with a volume of &gt;10 time
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Amit, Kumar, Kumari Jyoti, and Kumar Sujeet. "Assess Endometrial Biopsy Audit and its Clinico-Pathological Correlation in Patients with Abnormal Uterine Bleeding in Bihar Region." International Journal of Current Pharmaceutical Review and Research 15, no. 11 (2023): 208–11. https://doi.org/10.5281/zenodo.11551390.

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AbstractAim: The aim of the present study was to assess endometrial Biopsy Audit and its Clinico-PathologicalCorrelation in Patients with Abnormal Uterine Bleeding in Bihar regionMethods: The present study was conducted in the Department of Pathology over a period of 12 months. 200cases were selected in the study.Results: In the study majority 45% were in the age group 41 to 50 years. In the study 5% were Nulliparous andmajority were in para 2 (51%). In the study majority of subjects had Heavy menstrual bleeding (48%). In thestudy clinically, 48% were diagnosed to have fibroid, 25% had Adenomy
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Amarnath, Kumar Nayak, Debbarma Dipti, Rajnish Kumar, and Prakash Anand Anand. "Assessment of Endometrial Biopsy in Patients with Abnormal Uterine Bleeding: An Observational Study." International Journal of Current Pharmaceutical Review and Research 15, no. 10 (2023): 201–4. https://doi.org/10.5281/zenodo.11622597.

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AbstractAim: The aim of the present study was to assess endometrial Biopsy Audit and its Clinico-PathologicalCorrelation in Patients with Abnormal Uterine Bleeding in Bihar regionMethods: The present study was conducted in the Department of Pathology from February 2023 to June 2023.100 cases were selected in the study.Results: In the study majority 44% were in the age group 41 to 50 years. In the study 5% were Nulliparous andmajority were in para 2 (52%). In the study majority of subjects had Heavy menstrual bleeding (47%). In thestudy clinically, 46% were diagnosed to have fibroid, 24% had Ad
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Zhang, Airong, Xiujuan Liu, Juan Wang, Kui Deng, and Jianghua Wang. "MiR-30c-5p Directly Targets MAPK1 to Regulate the Proliferation, Migration and Invasion of Adenomyotic Epithelial Cells in Adenomyosis." Twin Research and Human Genetics 24, no. 1 (2021): 22–28. http://dx.doi.org/10.1017/thg.2021.11.

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AbstractThe purpose of our study was to elucidate the functions of miR-30c-5p on adenomyosis for exploring novel treatment strategies. We first detected the expression of miR-30c-5p in clinical adenomyotic tissues and isolated endometrial cells from adenomyotic tissues. Next, gain and loss-of-function assays were performed to detect the effect of miR-30c-5p on adenomyotic endometrial cells. Further, luciferase assay and real-time polymerase chain reaction as well as western blot were conducted to investigate the potential target of miR-30c-5p; and transwell assay, wound-healing assay and CCK-8
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Krut, Yu Ya, and N. A. Zemlyana. "Clinical-anamnestic and ELISA predictors of recurrence of endometrial hyperplastic processes in combination with uterine fibroids." Reproductive health of woman 5 (December 31, 2020): 48–52. http://dx.doi.org/10.30841/2708-8731.5.2021.224498.

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Endometrium hyperplastic processes (EHP) are characterized by high prevalence, high risk of malignancy and frequent recurrence.The objective: identify risk factors for recurrence in EHP in combination with uterine fibroids based on the study of clinical and anamnestic data and markers of oncogenesis.Materials and methods. The study examined 81 women with endometrial hyperplastic processes (34 women with simple endometrial hyperplasia without atypia and 47 women with complex endometrial hyperplasia without atypia), who were treated in the at the gynecological department of the “City Clinical Ho
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Yu., Ya. Krut, and A. Zemlyana N. "Clinical-anamnestic and ELISA predictors of recurrence of endometrial hyperplastic processes in combination with uterine fibroids." Reproductive health of woman 5 (December 31, 2020): 48–52. https://doi.org/10.30841/2708-8731.5.2021.224498.

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Endometrium hyperplastic processes (EHP) are characterized by high prevalence, high risk of malignancy and frequent recurrence. <strong>The objective:</strong>&nbsp;identify risk factors for recurrence in EHP in combination with uterine fibroids based on the study of clinical and anamnestic data and markers of oncogenesis. <strong>Materials and methods.</strong>&nbsp;The study examined 81 women with endometrial hyperplastic processes (34 women with simple endometrial hyperplasia without atypia and 47 women with complex endometrial hyperplasia without atypia), who were treated in the at the gyn
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35

Löffelmann, Anna C., Alena Hoerscher, Muhammad A. Riaz, Felix Zeppernick, Ivo Meinhold-Heerlein, and Lutz Konrad. "Claudin-10 Expression Is Increased in Endometriosis and Adenomyosis and Mislocalized in Ectopic Endometriosis." Diagnostics 12, no. 11 (2022): 2848. http://dx.doi.org/10.3390/diagnostics12112848.

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Claudins, as the major components of tight junctions, are crucial for epithelial cell-to-cell contacts. Recently, we showed that in endometriosis, the endometrial epithelial phenotype is highly conserved, with only minor alterations. For example, claudin-11 is strongly expressed; however, its localization in the endometriotic epithelial cells was impaired. In order to better understand the role of claudins in endometrial cell-to-cell contacts, we analyzed the tissue expression and localization of claudin-10 by immunohistochemistry analysis and two scoring systems. We used human tissue samples
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36

Dembele, Mamadou, Alassane Kouma, Ilias Guindo, et al. "ULTRASOUND IN THE ETIOLOGICAL ASSESSMENT OF EMBRYONIC IMPLANTATION FAILURES AT THE FERTILIA MEDICAL CLINIC IN BAMAKO." International Journal of Advanced Research 11, no. 06 (2023): 1324–30. http://dx.doi.org/10.21474/ijar01/17196.

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Recurrent implantation failure refers to failure to achieve a clinical pregnancy after the transfer of at least four embryos in at least three fresh or frozen cycles in a woman under 40 years of age. Implantation failure can be a consequence of embryonic or uterine factors. Thorough investigations must be necessary to determine whether there is an embryonic or uterine cause. Various uterine pathologies, including fibroids, endometrial lesions, polyps, congenital anomalies and intrauterine adhesions, vascular parameters should be explored by ultrasound to aid in the diagnosis of the causes of e
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37

Gladenko, S. E., and A. A. Dovgan. "Clinical-endocrinological and echografical aspects of good-quality dysplasia of mammary glands at women of reproductive age." HEALTH OF WOMAN, no. 8(144) (October 31, 2019): 75–77. http://dx.doi.org/10.15574/hw.2019.144.75.

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The objective: to study modern clinical-endocrinologic and echografical aspects of good-quality dysplasia of mammary glands at women of reproductive age. Materials and methods. Were surveyed 90 patients aged from 22 till 45 years which are divided into 3 groups on 30 women: 1 group - group of control - the woman without pathology in mammary glands. The 2nd group included patients with diffuse form of good-quality dysplasia of mammary glands. The 3rd group was made by patients with a nodal form of a good-quality dysplasia of mammary glands. The complex the researches included clinical, echograf
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38

Deryabina, Viktoriya A., Tatiana V. Brus, and Sarng S. Pyurveev. "Endometriosis and adenomyosis: common and disparate features." Pediatrician (St. Petersburg) 13, no. 5 (2022): 81–97. http://dx.doi.org/10.17816/ped13581-97.

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Endometriosis and adenomyosis are diseases of the gynecological profile, which are ectopic endometrioid tissue and have long been considered tangible manifestations of the process. Only recently have scientists begun to put forward a theory about the unequal origin of these pathologies. In endometriosis, the lining of the uterus extends beyond it, mainly to the ovaries, fallopian tubes, and bladder. With adenomyosis, the nodes grow into the muscular wall of her uterus and thicken. They do not go outside the uterus. Both conditions cause severe pain due to local inflammation, swelling and adhes
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39

Bashirov, E. V., V. A. Krutova, and I. I. Kutsenko. "Biomarkers of the type of recurrent uterine myoma-associated growth." Medical Herald of the South of Russia 12, no. 4 (2021): 6–11. http://dx.doi.org/10.21886/2219-8075-2021-12-4-6-11.

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Objective: To assess the diagnostic value of biomarkers: microbiological, molecular and biological, immunological biomarkers, characteristic of various types of recurrent myoma-associated growth.Materials and Methods: Seventy women of reproductive age with recurrent uterine myoma and its combination with adenomyosis after conservative treatment in the Clinic of Kuban State Medical University were examined. Methods: microbiological examination, sonography, Doppler sonography, histology, immunohistochemistry, morphometry.Results: The type of recurrent myoma-associated growth was proved to be dep
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Hadiprajitno, Peter Ivan, and Sultana Faradz. "Genetic Counseling in a Couple with Primary Infertility." Journal of Biomedicine and Translational Research 8, no. 3 (2022): 149–54. http://dx.doi.org/10.14710/jbtr.v8i3.16179.

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Background: Couples unable to conceive and bear children could feel deep disappointment, often leading to depression. Infertility is one of the main reasons couples are not able to have children. Genetic counseling role in infertility ranges from explanation about possible genetic causes of infertility, pregnancy planning, and advice for treatment. Case Presentation: A couple with 16 years of infertility was referred to the genetic clinic at National Diponegoro Hospital. The 42 years old female had previous history of diabetes mellitus, obesity, and had treatment of epilepsy/seizure 15 years a
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Maoga, Jane B., Muhammad A. Riaz, Agnes N. Mwaura, et al. "Impaired Expression of Membrane Type-2 and Type-3 Matrix Metalloproteinases in Endometriosis but Not in Adenomyosis." Diagnostics 12, no. 4 (2022): 779. http://dx.doi.org/10.3390/diagnostics12040779.

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Matrix metalloproteinases (MMPs) play an important role in menstruation and endometriosis; however, the membrane-type matrix metalloproteinases (MT-MMPs) are not well studied in endometriosis and adenomyosis. We analyzed MT2-MMP (MMP15) and MT3-MMP (MMP16) in eutopic endometrium with and without endometriosis and with and without adenomyosis and ectopic endometrium of deep infiltrating endometriosis (DIE), peritoneal endometriosis (PE), and ovarian endometriosis (Ov) by immunohistochemistry. Preferential expression of both proteins was observed in the glandular and luminal epithelial cells of
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42

Alkhamis, Areeb A., Basmah S. AlDeghaither, and Lateefa O. Aldakhil. "FIGO PALM–COEIN Classification of Abnormal Uterine Bleeding in Saudi Women." Saudi Journal of Medicine & Medical Sciences 12, no. 4 (2024): 314–18. http://dx.doi.org/10.4103/sjmms.sjmms_310_24.

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Abstract Background: Abnormal uterine bleeding (AUB) is a significant concern in women’s health. However, there is limited research on its prevalence and characteristics in Saudi Arabia. Objectives: To determine the prevalence of AUB in a gynecology outpatient setting in Saudi Arabia and to categorize the cases of AUB according to the FIGO classification. Methods: This retrospective study included all Saudi female patients who presented to the Obstetrics and Gynecology clinic at King Khalid University Hospital, Riyadh, Saudi Arabia, over a 2-year period, except those who were pregnant. Data re
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43

Alkatout, I., T. Becker, P. Nuhn, et al. "The first robotic-assisted hysterectomy below the bikini line with the Dexter robotic system™." Facts, Views and Vision in ObGyn 16, no. 1 (2024): 87–91. http://dx.doi.org/10.52054/fvvo.16.1.010.

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Background: Robotic-assisted hysterectomy (RAH) is a widely accepted minimally invasive approach for uterus removal. However, as RAH is typically performed in the umbilical region, it usually results in scars in cosmetically suboptimal locations. This is the first case of RAH with cervicosacropexy performed below the bikini line, using the new Dexter robotic system™. Objectives: The aim of this article is to show the surgical steps of the first RAH with cervicosacropexy performed below the bikini line with the new Dexter robotic system™ (Distalmotion), and furthermore assess the feasibility of
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44

Kravchenko, E. N., and E. V. Lautenschleger. "Endometrial hyperplasia and endometrial polyps: clinical and anamnestic characteristics of women." Fundamental and Clinical Medicine 8, no. 4 (2024): 16–23. http://dx.doi.org/10.23946/2500-0764-2023-8-4-16-23.

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Aim. To study the clinical and anamnestic characteristics of patients with endometrial hyperplasia (EH) and endometrial polyps (PE).Material and Methods. a retrospective study was conducted, which included 267 sick women of reproductive and perimenopausal age who sought gynecological care at «Euromed» in 2022-23, who, before receiving the examination results, were diagnosed with N92 - heavy, frequent and irregular menstruation. Depending on the results of the pathomorphological examination, the patients were divided into 3 groups: group A included 89 patients with GE; group B – 99 women with P
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45

Frijlingh, M., R. A. de Leeuw, L. J. M. Juffermans, T. van den Bosch, and J. A. F. Huirne. "Visualisation of microvascular flow in benign uterine disorders: a pilot study of a new diagnostic technique." Facts, Views and Vision in ObGyn 15, no. 2 (2023): 115–22. http://dx.doi.org/10.52054/fvvo.15.2.072.

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Background: Uterine disorders have clear overlapping symptoms and ultrasound discrimination is not always easy. Accurately measuring vascularity is of diagnostic and prognostic value. Power Doppler is limited to imaging only the larger vessels. Assessment of the microvasculature requires advanced machine settings. Objectives: In this pilot study, we aimed to test the feasibility of microvascular flow imaging of benign uterine disorders. Material and Methods: Two experienced gynaecologists (JH, RL) randomly applied power Doppler and MV-flowTM mode during a single day, in ten patients each visit
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46

KEPKEP, Necip, Coşkun ÖZSARAÇ, Suna ERKILIÇ, and Lügen CENGİZ. "Adenomyosis in 38 Hysterectomy Specimens." European Journal of Therapeutics 3, no. 2 (1992): 168–75. http://dx.doi.org/10.58600/eurjther.19920302-1053.

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Adenomyosis is the histopathological and clinical entity causes progressive seconder dysmenorrhea and menorrhagia in the mid aged parous women. Basal endometrium generally insensitive to ovarian hormo:ı;ı.es, lay within the myometrial layers. Adenomyosis was detected in 26 of 38 uteruses which were removed because of various indications in one year period in the Gynecological Oinic of the Medical School of Gaziantep University. Findings and clinics of adenomyosis were presented and discussed in the paper.
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47

Amin, Saira, Raham Bacha, Syed Muhammad Yousaf Farooq, et al. "Uterine Artery Doppler Indices in the Various Causes of Abnormal Uterine Bleeding Confirmed with Histopathology." Pakistan Journal of Medical and Health Sciences 16, no. 8 (2022): 466–68. http://dx.doi.org/10.53350/pjmhs22168466.

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Background: All disturbed pattern of bleeding which arises due to different reasons such as anovulation, pregnancy, uterine abnormalities and coagulopathies is termed as abnormal uterine bleeding (AUB). Abnormal uterine bleeding is present in many forms such as heavy bleeding, short menstrual cycle, excessive and heavy menstruation, uterine bleeding at irregular period, excessive and prolonged uterine bleeding. Abnormal uterine bleeding is mostly caused by benign findings such as endometrial hyperplasia or atrophy or benign polyps. Around 5–12% of Abnormal uterine bleeding results from Endomet
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Kuru, Oguzhan, Ipek Betul Ozcivit Erkan, Cansu Turker Saricoban, Utku Akgor, Neslihan Gokmen Inan, and Sennur Ilvan. "The Role of Endometrial Sampling before Hysterectomy in Premenopausal Women with Abnormal Uterine Bleeding." Journal of Clinical Medicine 13, no. 13 (2024): 3709. http://dx.doi.org/10.3390/jcm13133709.

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Background/Objectives: An endometrial sampling is recommended for patients experiencing abnormal uterine bleeding above the age of 40 or 45. Valid risk prediction models are needed to accurately assess the risk of endometrial cancer and avoid an unnecessary endometrial biopsy in premenopausal women. We aimed to assess the necessity and usefulness of preoperative endometrial sampling by evaluating premenopausal women who underwent hysterectomy for abnormal uterine bleeding after preoperative endometrial sampling at our clinic. Methods: A retrospective analysis was conducted on 339 patients who
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49

Rukhliada, N. N., and Y. V. Tsveliov. "Experience of surgical treatment of manifesting forms of adenomyosis." Journal of obstetrics and women's diseases 52, no. 3 (2003): 43–46. http://dx.doi.org/10.17816/jowd88969.

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One describes in this article the technique of performing surgeries with saved organs at manifested adenomyosis, one presents the treatment results of women with various clinico-morphological disease forms by means of different surgical methods.
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Moraru, Liviu, Melinda-Ildiko Mitranovici, Diana Maria Chiorean, et al. "Adenomyosis and Its Possible Malignancy: A Review of the Literature." Diagnostics 13, no. 11 (2023): 1883. http://dx.doi.org/10.3390/diagnostics13111883.

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Cancer arising from adenomyosis is very rare, with transformation occurring in only 1% of cases and in older individuals. Adenomyosis, endometriosis and cancers may share a common pathogenic mechanism that includes hormonal factors, genetic predisposition, growth factors, inflammation, immune system dysregulation, environmental factors and oxidative stress. Endometriosis and adenomyosis both exhibit malignant behaviour. The most common risk factor for malignant transformation is prolonged exposure to oestrogens. The golden standard for diagnosis is histopathology. Colman and Rosenthal emphasis
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