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Journal articles on the topic 'Clinical and Chronological'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

van der Kamp, Martine Froukje, Eric Hiddingh, Julius de Vries, et al. "Association of Tumor Microenvironment with Biological and Chronological Age in Head and Neck Cancer." Cancers 15, no. 15 (2023): 3834. http://dx.doi.org/10.3390/cancers15153834.

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There is often a mismatch between the chronological and biological age of head and neck squamous cell carcinoma (HNSCC) patients. Treatment is based on chronological age, while biological age seems to be a better prognosticator for treatment toleration. This study investigated whether tumor characteristics are associated with chronological and biological age. The relation with survival was also assessed. Prospectively collected data from 164 newly diagnosed HNSCC patients enrolled in the OncoLifeS database were analyzed. Biological age was assessed by a multidomain geriatric assessment. Severa

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Lee, Chun Hwan, Sun Il Lee, Keun Won Ryu, and Young Jae Mok. "Chronological Changes in the Clinical Features of Gastric Cancer." Journal of the Korean Gastric Cancer Association 1, no. 3 (2001): 161. http://dx.doi.org/10.5230/jkgca.2001.1.3.161.

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Zeeh, Friederike, Maja M. Suter, Eliane Mueller, et al. "Chronological clinical and pathological documentation of porcine ulcerative dermatitis." Veterinary Dermatology 27, no. 4 (2016): 315—e78. http://dx.doi.org/10.1111/vde.12324.

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Thyparambil, Sheeno P., Xiurui Zhu, Yani Zhang, et al. "Deviation from the precisely timed age-associated patterns revealed by blood metabolomics to find CRC patients at risk of relapse at the CRC diagnosis." Journal of Clinical Oncology 40, no. 4_suppl (2022): 206. http://dx.doi.org/10.1200/jco.2022.40.4_suppl.206.

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206 Background: Human serum metabolome profiles have been analyzed to explore the molecular changes that occur with aging. We hypothesized that deep metabolic profiling of sera with different ages would allow the identification of distinct metabolic chronologic patterns as a normal biological baseline to study personal aging. We further hypothesized that metabolic assessment of this chronologic deviation, resulting from advanced precancerous lesion (APL) and stage I/II/III CRC, from the normal reference baseline, would be instrumental for prognosis of relapse revealing underlying pathophysiolo

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Mustafa, Wan Azani, Shahrina Ismail, Fahirah Syaliza Mokhtar, Hiam Alquran, and Yazan Al-Issa. "Cervical Cancer Detection Techniques: A Chronological Review." Diagnostics 13, no. 10 (2023): 1763. http://dx.doi.org/10.3390/diagnostics13101763.

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Cervical cancer is known as a major health problem globally, with high mortality as well as incidence rates. Over the years, there have been significant advancements in cervical cancer detection techniques, leading to improved accuracy, sensitivity, and specificity. This article provides a chronological review of cervical cancer detection techniques, from the traditional Pap smear test to the latest computer-aided detection (CAD) systems. The traditional method for cervical cancer screening is the Pap smear test. It consists of examining cervical cells under a microscope for abnormalities. How

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Yamaki, T., K. Hirakawa, T. Ueguchi, H. Tenjin, T. Kuboyama, and Y. Nakagawa. "Chronological evaluation of acute traumatic intracerebral haematoma." Acta Neurochirurgica 103, no. 3-4 (1990): 112–15. http://dx.doi.org/10.1007/bf01407516.

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Landgraf, Steffen, Susanne Raisig, and Elke van der Meer. "Discerning Temporal Expectancy Effects in Script Processing: Evidence from Pupillary and Eye Movement Recordings." Journal of the International Neuropsychological Society 18, no. 2 (2012): 351–60. http://dx.doi.org/10.1017/s1355617711001809.

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AbstractAccessing the temporal position of events (early or late in the event sequence) can influence the generation of predictions about upcoming events. However, it is unclear how the temporal position is processed strategically. To investigate this, we presented event pairs to 23 healthy volunteers manipulating temporal order (chronological, inverse) and temporal position (early, late). Pupil dilation, eye movements, and behavioral data, showed that chronological and early event pairs are processed with more ease than inverse and late event pairs. Indexed by the pupillary response late even

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Penninx, B. "Chronological and biological age: Why relevant for psychiatrists?" European Psychiatry 64, S1 (2021): S62. http://dx.doi.org/10.1192/j.eurpsy.2021.194.

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IntroductionDepression is the mental disorder with the largest disease burden impact. That is due to its high prevalence, chronicty, early onset but also due to its impact on various aging-related somatic morbidities and mortality. This talk will describes to what extent depression characteristics are related to chronologial and biological aging patterns.MethodsData will be shown from the Netherlands Study of Depression and Anxiety (NESDA, www.nesda.nl). In this study, a large cohort of over 3000 individuals (18-65 years), among which over 1200 with a DSM-based major depressive disorder (MDD),

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Steinberg, Paul. "Reading Freud: a chronological exploration of Freud’s writings." Psychodynamic Practice 19, no. 4 (2013): 424–30. http://dx.doi.org/10.1080/14753634.2013.853494.

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Trojahn, Carina, Gabor Dobos, Andrea Lichterfeld, Ulrike Blume-Peytavi, and Jan Kottner. "Characterizing Facial Skin Ageing in Humans: Disentangling Extrinsic from Intrinsic Biological Phenomena." BioMed Research International 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/318586.

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Facial skin ageing is caused by intrinsic and extrinsic mechanisms. Intrinsic ageing is highly related to chronological age. Age related skin changes can be measured using clinical and biophysical methods. The aim of this study was to evaluate whether and how clinical characteristics and biophysical parameters are associated with each other with and without adjustment for chronological age. Twenty-four female subjects of three age groups were enrolled. Clinical assessments (global facial skin ageing, wrinkling, and sagging), and biophysical measurements (roughness, colour, skin elasticity, and

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Antonio, Joao Roberto, Eny Maria Goloni-Bertollo, and Livia Arroyo Tridico. "Neurofibromatosis: chronological history and current issues." Anais Brasileiros de Dermatologia 88, no. 3 (2013): 329–43. http://dx.doi.org/10.1590/abd1806-4841.20132125.

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Neurofibromatosis, which was first described in 1882 by Von Recklinghausen, is a genetic disease characterized by a neuroectodermal abnormality and by clinical manifestations of systemic and progressive involvement which mainly affect the skin, nervous system, bones, eyes and possibly other organs. The disease may manifest in several ways and it can vary from individual to individual. Given the wealth of information about neurofibromatosis, we attempted to present this information in different ways. In the first part of this work, we present a chronological history, which describes the evoluti

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Takasugi, S., S. Ueda, and K. Matsumoto. "Chronological changes in spontaneous intracerebral hematoma--an experimental and clinical study." Stroke 16, no. 4 (1985): 651–58. http://dx.doi.org/10.1161/01.str.16.4.651.

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Shrira, Amit, Dikla Segel-Karpas, Ehud Bodner, and Yuval Palgi. "Subjective Age and Emotion Covariation: Findings From Two Daily Experience Studies." Journals of Gerontology: Series B 75, no. 5 (2018): 991–1000. http://dx.doi.org/10.1093/geronb/gby125.

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Abstract Objectives This article focuses on an aspect of emotional complexity as seen in the covariation between positive affect (PA) and negative affect (NA). Lifespan theories predict distinctive patterns of change in emotion covariation with chronological age. Nevertheless, research shows mixed evidence with most studies failing to find a significant connection between chronological age and emotion covariation. We propose to look beyond chronological age and assess the relationship between subjective age and emotion covariation. Subjective age refers to how old one perceives oneself to be,

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Hilgers, R. D., and M. Tamm. "Chronological Bias in Randomized Clinical Trials Arising from Different Types of Unobserved Time Trends." Methods of Information in Medicine 53, no. 06 (2014): 501–10. http://dx.doi.org/10.3414/me14-01-0048.

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SummaryBackground: In clinical trials patients are commonly recruited sequentially over time incurring the risk of chronological bias due to (unobserved) time trends. To minimize the risk of chronological bias, a suitable randomization procedure should be chosen.Objectives: Considering different time trend scenarios, we aim at a detailed evaluation of the extent of chronological bias under permuted block randomization in order to provide recommendations regarding the choice of randomization at the design stage of a clinical trial and to assess the maximum extent of bias for a realized sequence

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Khokhlov, L. К. "Pathomorphosis in clinical practice." Patient-Oriented Medicine and Pharmacy 1, no. 4 (2023): 1–7. http://dx.doi.org/10.37489/2949-1924-0026.

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The consideration of pathomorphosis makes it possible to assess the role of various factors in the occurrence, pathogenesis, specific manifestations, and content of pathology, to determine the boundaries of chronological dynamics, its modification, and, accordingly, to orient therapeutic and preventive measures. The urgency of this problem is caused by the rapidly increasing changes that are taking place in the life of modern society, with an abundance of information sources, the increasing activity of medical services to protect the health of the population, and the growth and accessibility o

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Aminabadi, Naser Asl, Sina Ghertasi Oskouei, and Ramin Mostofi Zadeh Farahani. "Dental Treatment Duration as an Indicator of the Behavior of 3- to 9- Year-old Pediatric Patients in Clinical Dental Settings." Journal of Contemporary Dental Practice 10, no. 5 (2009): 23–32. http://dx.doi.org/10.5005/jcdp-10-5-23.

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Abstract Aim The aim of this study was to evaluate the age-specific effect of treatment duration on pediatric patient behavior. Methods and Materials A total of 450 children 3 to 9 years of age were allocated into six consecutive age groups (n=75 for each group). All children received dental treatment procedures which included the fabrication of a Type 1 composite resin restoration, then a dental prophylaxis followed by fluoride therapy with each procedure requiring an average of 20 minutes. The children's behavior was evaluated at the end of each treatment period using the sound, eye, and mot

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Dow, Rebecca, Mhairi Donaldson, and Sarah Butchard. "Psychological impact of the response to the coronavirus/Covid-19 on older people." Clinical Psychology Forum 1, no. 329 (2020): 48–49. http://dx.doi.org/10.53841/bpscpf.2020.1.329.48.

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Any decisions about the care and support provided for older people in response to the current situation with Covid-19 require careful consideration of many factors, not just chronological age. The older population is a heterogeneous group with varying levels of vulnerability and resources. We welcome that the government has recommended people stay at home based on existing medical conditions rather than just chronological age. The self-isolation of members of the older population is likely to result in higher levels of mental distress and loneliness in this population, which requires attention

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Fischer, Tim, Yassir El Baz, Nicole Graf, et al. "Clinical and Imaging Features of COVID-19-Associated Pulmonary Aspergillosis." Diagnostics 12, no. 5 (2022): 1201. http://dx.doi.org/10.3390/diagnostics12051201.

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Background: COVID-19 superinfection by Aspergillus (COVID-19-associated aspergillosis, CAPA) is increasingly observed due to increased awareness and use of corticosteroids. The aim of this study is to compare clinical and imaging features between COVID-19 patients with and without associated pulmonary aspergillosis. Material and Methods: In this case–control study, hospitalized patients between March 2020 and March 2021 were evaluated. Two observers independently compared 105 chest CTs of 52 COVID-19 patients without pulmonary aspergillosis to 40 chest CTs of 13 CAPA patients. The following fe

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Roder, Constantin, Till-Karsten Hauser, Ulrike Ernemann, Marcos Tatagiba, Nadia Khan, and Benjamin Bender. "Arterial wall contrast enhancement in progressive moyamoya disease." Journal of Neurosurgery 132, no. 6 (2020): 1845–53. http://dx.doi.org/10.3171/2019.2.jns19106.

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OBJECTIVEThe purpose of this study was to evaluate chronological patterns of arterial wall contrast enhancement in contrast-enhanced high-resolution MRI (CE-HR-MRI) in patients with moyamoya disease (MMD).METHODSThe authors performed a blinded analysis of clinical and imaging data from MMD patients. Data were analyzed chronologically for each patient and the intensity of arterial wall enhancement was correlated with the clinical and imaging-based progression status of the disease.RESULTSA total of 31 MMD patients and 61 imaging time points were included. CE-HR-MRI results were available for 56

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Larocca, Dana, Jieun Lee, Michael D. West, Ivan Labat, and Hal Sternberg. "No Time to Age: Uncoupling Aging from Chronological Time." Genes 12, no. 5 (2021): 611. http://dx.doi.org/10.3390/genes12050611.

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Multicellular life evolved from simple unicellular organisms that could replicate indefinitely, being essentially ageless. At this point, life split into two fundamentally different cell types: the immortal germline representing an unbroken lineage of cell division with no intrinsic endpoint and the mortal soma, which ages and dies. In this review, we describe the germline as clock-free and the soma as clock-bound and discuss aging with respect to three DNA-based cellular clocks (telomeric, DNA methylation, and transposable element). The ticking of these clocks corresponds to the stepwise prog

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Zaborowicz, Katarzyna, Barbara Biedziak, Aneta Olszewska, and Maciej Zaborowicz. "Tooth and Bone Parameters in the Assessment of the Chronological Age of Children and Adolescents Using Neural Modelling Methods." Sensors 21, no. 18 (2021): 6008. http://dx.doi.org/10.3390/s21186008.

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The analog methods used in the clinical assessment of the patient’s chronological age are subjective and characterized by low accuracy. When using those methods, there is a noticeable discrepancy between the chronological age and the age estimated based on relevant scientific studies. Innovations in the field of information technology are increasingly used in medicine, with particular emphasis on artificial intelligence methods. The paper presents research aimed at developing a new, effective methodology for the assessment of the chronological age using modern IT methods. In this paper, a stud

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Tsujikawa, Koyo, Yasuhiro Hasegawa, Satoshi Yokoi, et al. "Chronological changes of123I-MIBG myocardial scintigraphy and clinical features of Parkinson's disease." Journal of Neurology, Neurosurgery & Psychiatry 86, no. 9 (2015): 945–51. http://dx.doi.org/10.1136/jnnp-2015-310327.

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Simms, Mary. "A theory of age exclusion through closure: ‘Chronological age’ to ‘clinical need’." Journal of Aging Studies 18, no. 4 (2004): 445–65. http://dx.doi.org/10.1016/j.jaging.2004.06.003.

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Yakhontov, D. A., Yu O. Ostanina, and A. P. Lykov. "Coronary artery disease with intermediate coronary artery stenosis. Clinical peculiarities. The chronological age and biological age ratio." JOURNAL of SIBERIAN MEDICAL SCIENCES 6, no. 4 (2022): 37–47. http://dx.doi.org/10.31549/2542-1174-2022-6-4-37-47.

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Introduction. Coronary artery disease (CAD) remains the main cause of disability and mortality among working-age people. A significant part of stable angina patients are patients with intermediate (40–70%) coronary artery stenosis. Aim. To study cardiovascular risk factors and make a comparative assessment of the clinical angiographic picture and vascular stiffness in stable angina patients with intermediate coronary artery stenosis, depending on the chronological age / biological age ratio, as well as to determine the level of long-term metabolites of nitric oxide (NO) – nitrites (NO2) . Mate

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Zdravkovic, Dejan, Milica Jovanovic, Milos Papic, et al. "Application of the Kvaal Method in Age Estimation of the Serbian Population Based on Dental Radiographs." Diagnostics 12, no. 4 (2022): 911. http://dx.doi.org/10.3390/diagnostics12040911.

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This study aimed to evaluate the applicability of the Kvaal method in determining the age of a Serbian population. In this retrospective descriptive study, 170 dental patients (age range 16–77 years) were included. The measurements of six types of teeth were performed on digital orthopantomography radiographs according to the Kvaal method. Statistical inter-observer and intra-observer reliabilities were calculated to evaluate the reproducibility of the measurements, as well as to examine the correlation between chronological age and measured values. The evaluation revealed a substantial differ

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Berben, Lieze, Asier Antoranz, Cindy Kenis, et al. "Blood Immunosenescence Signatures Reflecting Age, Frailty and Tumor Immune Infiltrate in Patients with Early Luminal Breast Cancer." Cancers 13, no. 9 (2021): 2185. http://dx.doi.org/10.3390/cancers13092185.

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Background: Immune/senescence-related host factors play a pivotal role in numerous biological and pathological process like aging, frailty and cancer. The assessment of these host factors via robust, non-invasive, and easy-to-measure blood biomarkers could improve insights in these processes. Here, we investigated in a series of breast cancer patients in which way single circulating biomarkers or biomarker panels relate to chronological age, frailty status, and tumor-associated inflammatory microenvironment. Methods: An extensive panel of blood immune/senescence markers and the tumor immune in

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Jaafar, Ahmed F., Robert Heycock, and James George. "Frailty–a clinical overview." Reviews in Clinical Gerontology 17, no. 3 (2007): 171–75. http://dx.doi.org/10.1017/s0959259808002542.

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Frailty as a concept has been around in medical practice for many years but has only relatively recently been established as a medical syndrome. Although frailty is not synonymous with chronological age, it is recognized to be more common as people get older. Frailty is independently associated with increasing dependency, hospital admissions and morbidity and mortality. As populations age, frailty will become more of a challenge to health care systems. It is important that health care professionals, especially geriatricians, are aware of this emerging syndrome and its potential adverse outcome

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Madsen, André, Ninnie B. Oehme, Mathieu Roelants, et al. "Testicular Ultrasound to Stratify Hormone References in a Cross-Sectional Norwegian Study of Male Puberty." Journal of Clinical Endocrinology & Metabolism 105, no. 6 (2019): 1888–98. http://dx.doi.org/10.1210/clinem/dgz094.

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Abstract Context Testicular growth represents the best clinical variable to evaluate male puberty, but current pediatric hormone references are based on chronological age and subjective assessments of discrete puberty development stages. Determination of testicular volume (TV) by ultrasound provides a novel approach to assess puberty progression and stratify hormone reference intervals. Objective The objective of this article is to establish references for serum testosterone and key hormones of the male pituitary-gonadal signaling pathway in relation to TV determined by ultrasound. Design, Set

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Lev, I. V., N. M. Agarkov, and A. E. Kopylov. "Dissociation of biological age and blood interleukins in patients aged 45–59 years with diabetic retinopathy in type 2 diabetes mellitus." Acta Biomedica Scientifica 8, no. 4 (2023): 170–76. http://dx.doi.org/10.29413/abs.2023-8.4.19.

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Background. The development of diabetic retinopathy is favoured by immunological factors such as interleukins (IL) and chemokines. However, analysis of blood interleukins in patients aged 45–59 years with diabetic retinopathy in type 2 diabetes mellitus, who have biological age acceleration, has not yet been presented in publications. The aim of the research. To study the content of blood interleukins in patients aged 45–59 years with diabetic retinopathy in type 2 diabetes mellitus, who have an excess of biological age over chronological age. Materials and methods. 241 patients aged 45–59 yea

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Panat, Ulupi, Javed Sodawala, Stuti Shukla, Charwak Tayade, Veethika J. Thakur, and Akhilesh Belchandan. "Comparison of Salivary Alkaline Phosphatase Activity and Cervical Vertebral Maturation Stages as Indicators for Skeletal Maturity." Journal of Pharmacy and Bioallied Sciences 17, Suppl 2 (2025): S1547—S1549. https://doi.org/10.4103/jpbs.jpbs_108_25.

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ABSTRACT Introduction: Evaluating skeletal maturity is essential for determining the appropriate timing of orthopedic and orthodontic therapies. Noninvasive approaches to skeletal maturity assessment are increasingly being researched for their clinical applicability. Materials and Methods: This study included 110 participants (53 males, 57 females) aged 7–23 years. Lateral cephalograms classified subjects into five cervical vertebral maturation stages (CVMS) with 22 participants in each group. Salivary alkaline phosphatase (ALP) activity and total protein concentration were measured. Pearson c

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Chromecki, T., E. K. Cha, K. Pummer, and S. F. Shariat. "Chronological age is not an independent predictor of clinical outcomes after radical nephroureterectomy." Journal of Men's Health 8, no. 3 (2011): 216–17. http://dx.doi.org/10.1016/j.jomh.2011.08.029.

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Chromecki, Thomas F., Behfar Ehdaie, Giacomo Novara, et al. "Chronological age is not an independent predictor of clinical outcomes after radical nephroureterectomy." World Journal of Urology 29, no. 4 (2011): 473–80. http://dx.doi.org/10.1007/s00345-011-0677-0.

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Galkin, Fedor, Austin Parish, Evelyne Bischof, John Zhang, Polina Mamoshina, and Alex Zhavoronkov. "Increased Pace of Aging in COVID-Related Mortality." Life 11, no. 8 (2021): 730. http://dx.doi.org/10.3390/life11080730.

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Identifying prognostic biomarkers and risk stratification for COVID-19 patients is a challenging necessity. One of the core survival factors is patient age. However, chronological age is often severely biased due to dormant conditions and existing comorbidities. In this retrospective cohort study, we analyzed the data from 5315 COVID-19 patients (1689 lethal cases) admitted to 11 public hospitals in New York City from 1 March 2020 to 1 December. We calculated patients’ pace of aging with BloodAge—a deep learning aging clock trained on clinical blood tests. We further constructed survival model

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Al-Rashdan, Abdulla, Melina Deban, May Lynn Quan, and Jeffrey Q. Cao. "Locoregional Management of Breast Cancer: A Chronological Review." Current Oncology 29, no. 7 (2022): 4647–64. http://dx.doi.org/10.3390/curroncol29070369.

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Locoregional management of breast cancer is founded on evidence generated over a vast time period, much longer than the career span of many practicing physicians. Oncologists rely on specific patient and tumour characteristics to recommend modern-day treatments. However, some of this information may not have been available during prior periods in which the evidence was generated. For example, the comprehensive Early Breast Cancer Trialists’ Collaborative Group (EBCTCG) meta-analyses published in the 2000s typically included older trials accruing patients between the 1960s and 1980s. This raise

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Wang, Vania, Yash Chhabra, Laura Hueser, Sneha Pramod, Alexis Carey, and Ashani Weeraratna. "Abstract 1274: Extrinsic photoaging vs intrinsic aging in dermal fibroblasts: Its impact on the microenvironment and melanoma progression." Cancer Research 83, no. 7_Supplement (2023): 1274. http://dx.doi.org/10.1158/1538-7445.am2023-1274.

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Abstract Melanoma is the deadliest form of skin cancer, with its incidence rising disproportionally to other cancers. Chronological aging is a major risk factor in all types of cancer as it has been shown to drive changes in noncancerous cells (stromal and immune) of the tumor microenvironment (TME) to promote tumor initiation and progression. Ultraviolet radiation (UVR) exposure, which is a major risk factor for melanoma, also can cause a physical premature aging phenotype, known as photoaging. Photoaging of the skin often occurs in tandem with chronological aging, and contributes to the phys

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Khanal, Sanskriti, Jemish Acharya, and Priyanka Shah. "Dental Age Estimation by Demirjian’s and Nolla’s Method in Children of Jorpati, Kathmandu." Journal of College of Medical Sciences-Nepal 14, no. 3 (2018): 137–41. http://dx.doi.org/10.3126/jcmsn.v14i3.20733.

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Background: Growing individuals not only differ in the timing of the maturational events, but also in the sequence of these events. Age is one of the essential factors, which play an important role in every aspect of life like in clinical, medico-legal, forensic and anthropological applications and in planning treatment of orthodontic and pedodontic patients. The aim of the study was to determine dental age from orthopantomogram using Demirjian’s method and Nolla’s method and to evaluate the interrelationship between chronological and dental age according to both these methods. Materials and M

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Pandian, Muthuchitra, Anjali Sabnis, and Shroff Gautam. "Anatomical variations of sulci in human fetal cerebrum and its clinical significance." Biomedicine 41, no. 3 (2021): 539–42. http://dx.doi.org/10.51248/.v41i3.691.

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Introduction and Aim: Appearance of sulci and its number in the fetal cerebrum is a signal of growth and development. Chronological appearance and symmetrical development of sulci corresponds to gestational age of fetus. Few sulci can be visualized in the prenatal period to judge the growth of fetus. Any change in chronological appearance, symmetry and number of sulci in fetal cerebrum is of prime importance. Materials and Methods: Hundred and six cerebral hemispheres of 53 fetal brains of different gestational ages were collected from MGM Hospital Kalamboli and Aurangabad after institutional

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Montojo, María Teresa, Miguel Aganzo, and Nieves González. "Huntington’s Disease and Diabetes: Chronological Sequence of its Association." Journal of Huntington's Disease 6, no. 3 (2017): 179–88. http://dx.doi.org/10.3233/jhd-170253.

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Shindo, Kazumasa, Chikashi Shimokawa, Harue Watanabe, et al. "Chronological changes of sympathetic outflow to muscles in amyotrophic lateral sclerosis." Journal of the Neurological Sciences 227, no. 1 (2004): 79–84. http://dx.doi.org/10.1016/j.jns.2004.08.006.

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Ambreen, Sadaf. "COMPARISION OF DENTAL SCORING SYSTEM WITH RADIOGRAPHIC SKELETAL SYSTEM IN AGE ESTIMATION." JKCD 9, no. 1 (2019): 9–11. http://dx.doi.org/10.33279/2307-3934.2019.9103.

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Objectives: To compare Demirjian Dental scoring method with Greulich-Pyle (GP) Skeletal method of age estimation in pubertal children. Materials and Methods: Sample of the study included 267 male healthy subjects of 11-16 years of age group.. Demirjian Scoring system was utilized to evaluate the orthopantomograms to assess their Dental age and the Hand-Wrist radiographs were analyzed to calculate the skeletal age by utilizing GP atlas. Chronological age was obtained from the date of birth of the subject .Both methods were compared with one another and with the chronological age. It was a cross

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Grigore, Ioana, Georgeta Diaconu, N. Nistor, Ioana Cernescu, and Irina Ciomaga. "VARICELLA ZOSTER VIRUS FETOPATHY – CLINICAL CASE." Romanian Journal of Pediatrics 64, no. 2 (2015): 158–60. http://dx.doi.org/10.37897/rjp.2015.2.11.

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Varicella zoster virus fetopathy occurs in infants after infection with varicella-zoster virus from mother during the first two trimesters of pregnancy. The authors describe the case of a female infant, aged 4 months, which came under observation for neuro developmental delay for chronological age. Neurological exam, abnormalities detected on ophthalmologic examination, maternal history of gestational varicella and increased IgG titer to varicella-zoster virus supported the diagnosis of varicella zoster virus fetopathy. Varicella zoster virus fetopathy is a condition characterized by severe sk

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Inamoto, Teruo, Hideyasu Matsuyama, Naokazu Ibuki, et al. "Risk stratification by means of biological age-related factors better predicts cancer-specific survival than chronological age in patients with upper tract urothelial carcinoma: a multi-institutional database study." Therapeutic Advances in Urology 10, no. 12 (2018): 403–10. http://dx.doi.org/10.1177/1756287218811050.

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Background: Chronological age is an important factor in determining the treatment options and clinical response of patients with upper tract urothelial carcinoma (UTUC). Much evidence suggests that chronological age alone is an inadequate indicator to predict the clinical response to radical nephroureterectomy (RNU). Patients and methods: We retrospectively reviewed the data from 1510 patients with UTUC (Ta-4) treated by surgery. White blood cell (WBC) count, neutrophil-to-lymphocyte ratio, hemoglobin (Hb), platelets, albumin, alkaline phosphatase, lactate dehydrogenase, creatinine, and correc

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Cegła, Paulina, and Tomasz Piotrowski. "History of positron emission tomography (PET) in Poland." Bio-Algorithms and Med-Systems 17, no. 4 (2021): 259–64. http://dx.doi.org/10.1515/bams-2021-0145.

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Abstract In this short chronological review, we showed the development of positron emission tomography (PET) starting from research on first isotopes through the concepts and prototype of PET machine to the current clinical practice and technological and clinical research. Particular emphasis was placed on a clear description of the milestones of PET development in Poland.

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Gould, Jacqueline F., Belinda G. Fuss, Rachel M. Roberts, Carmel T. Collins, and Maria Makrides. "Consequences of using chronological age versus corrected age when testing cognitive and motor development in infancy and intelligence quotient at school age for children born preterm." PLOS ONE 16, no. 9 (2021): e0256824. http://dx.doi.org/10.1371/journal.pone.0256824.

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Background Children born preterm (<37 weeks’ gestation) have an increased risk of poor neurodevelopment, including lower intelligence quotient (IQ) scores compared with their term-born counterparts. Objective To explore the differences in psychometric scores for cognition and motor skills when they are age-standardized according to chronological age instead of corrected age for children born preterm. Methods We assessed = 554 children born <33 weeks’ gestation with the Bayley Scales of Infant Development, 2nd edition (mental and motor scores) at 18 months and the Weschler Abbreviated Sca

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Carelli, Julia, Gabriela Sabrina da Silva, Mariana Vegini Gomes, et al. "Demirjian’s and Cameriere’s Methods for the Assessment of Dental Age Estimation in Children from a Southern Brazilian City." Diagnostics 14, no. 14 (2024): 1513. http://dx.doi.org/10.3390/diagnostics14141513.

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The chronological age estimation of living individuals is a crucial part of forensic practice and clinical practice, such as in orthodontic treatment. It is well-known that methods for age estimation in living children should be tested on different populations. Ethnic affiliations in Brazil are divided into several major groups depending on the region, with the south of Brazil being known for its German immigration. (1) Background: This study aimed to evaluate the correlation between chronological age and dental age using Demirjian’s method and Cameriere’s method in a group of children from Jo

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Davinelli, Sergio, Juan Carlos Bertoglio, Ascanio Polimeni, and Giovanni Scapagnini. "Cytoprotective Polyphenols Against Chronological Skin Aging and Cutaneous Photodamage." Current Pharmaceutical Design 24, no. 2 (2018): 99–105. http://dx.doi.org/10.2174/1381612823666171109102426.

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Background: Skin aging is a complex biological process influenced by a combination of intrinsic and extrinsic factors, leading to cumulative alterations of skin structure, function and appearance. Polyphenols, which are secondary plant metabolites, represent one of the largest classes of compounds used in dermatology and nutricosmetics to combat skin aging. The main objective is to provide an overview of the existing literature linking skin aging and the ability of polyphenols as regulatory elements able to maintain skin homeostasis. Methods: In this review, we discuss recent progress in under

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Armstrong, Kaylynn, Hend Nadim, DaiWai Olson, and Sonja Stutzman. "Use of modified Delphi introduces the risk of chronological bias during clinical research interventions." Nurse Researcher 29, no. 1 (2021): 9–13. http://dx.doi.org/10.7748/nr.2020.e1742.

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Koyama, Shingo, Asako Nogami, Masato Yoneda, et al. "Chronological Course and Clinical Features after Denver Peritoneovenous Shunt Placement in Decompensated Liver Cirrhosis." Tomography 10, no. 4 (2024): 471–79. http://dx.doi.org/10.3390/tomography10040036.

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Background: Refractory ascites affects the prognosis and quality of life in patients with liver cirrhosis. Peritoneovenous shunt (PVS) is a treatment procedure of palliative interventional radiology for refractory ascites. Although it is reportedly associated with serious complications (e.g., heart failure, thrombotic disease), the clinical course of PVS has not been thoroughly evaluated. Objectives: To evaluate the relationship between chronological course and complications after PVS for refractory ascites in liver cirrhosis patients. Materials and Methods: This was a retrospective study of 1

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Dhillon, Vikram, Jeff Aguilar, and Suresh Kumar Balasubramanian. "Epigenetic Age Acceleration in Hematological Malignancies: Beyond Chronological Age, Clinical Implications, and Therapeutic Perspectives." Blood 142, Supplement 1 (2023): 126. http://dx.doi.org/10.1182/blood-2023-191310.

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Background: Age is important in prognosticating hematological malignancies. Biological based on DNA methylome changes offers new insights into the complex interplay between epigenetics, genetics, environment, and cancer. DNA methylation levels at specific CpG sites evolve in a predictable fashion with aging and can be used to develop biomarkers that estimate the epigenetic age (EA) of a tissue. Such biomarkers are called epigenetic clocks (Fig 1-B). Based on the EA, we can determine Epigenetic Age Acceleration (EAA), a tool to identify patients aging faster biologically than their chronologica

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Joshi, Harendra I. "P1-429: Chronological events in neurological diseases." Alzheimer's & Dementia 2 (July 2006): S223. http://dx.doi.org/10.1016/j.jalz.2006.05.808.

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