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Dissertations / Theses on the topic 'Clinical Application of iPS Cells'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Ang, Main-fong, and 洪明楓. "Ex vivo expansion of hematopoietic stem cells: preclinical studies and clinical application." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B3122815X.

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2

Scott, Michael Andrew. "Biology and clinical application of peripheral blood stem cells mobilised by pharmacological agents." Thesis, Anglia Ruskin University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363925.

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3

Wang, Wenxia, Zhenbo Zhang, Yin Zhao, et al. "Enrichment and characterization of ovarian cancer stem cells and its potential clinical application." E-CENTURY PUBLISHING CORP, 2017. http://hdl.handle.net/10150/622725.

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The cancer stem cell (CSC) theory proposes that a minor population in tumor cells with specific features, such as self-renewal and reproducible tumor phenotype could contribute to tumor relapse and chemotherapy resistance. Several studies have convincingly documented the existence of ovarian CSC, but questions related to the biologic behavior and specific biomarkers of ovarian CSC remain to be clarified. In the present study, we firstly established a tumor cell line with capability of regenerating tumors through serial transplantation of ovarian tumor tissue in non-obese/severe combined immuno

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4

Roychowdhury, Sameek. "Interleukin-15 biology, pathophysiology, and pre-clinical application in disease /." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1084884532.

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Thesis (Ph. D.)--Ohio State University, 2004.<br>Title from first page of PDF file. Document formatted into pages; contains iii, vii, 119 p.; also includes graphics (some col.) Includes bibliographical references (p. 102-119). Available online via OhioLINK's ETD Center

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5

Espinha, Nuno Miguel Moura. "Bioprocess engineering of induced pluripotent stem cells for application in cell therapy and pre-clinical research." Master's thesis, Faculdade de Ciências e Tecnologia, 2014. http://hdl.handle.net/10362/11551.

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6

APRILE, LARA. "Flow-cytometry evaluation of residual Leukemia Stem Cells in Chronic Myeloid Leukemia patients: feasibility and clinical application." Doctoral thesis, Università di Siena, 2017. http://hdl.handle.net/11365/1010532.

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Chronic Myeloid Leukemia (CML) is a myeloproliferative disorder characterized by the presence of the BCR-ABL1 oncogene, deriving from the t(9;22)-(q34;q11) balanced translocation. The deriving BCR-ABL1 fusion protein has tyrosine kinase activity, and it is capable of inducing the proliferation and expansion of myeloid precursors. Tyrosine kinase inhibitors, drugs capable of blocking the malignant proliferation of cells by directly targeting the BCR-ABL1 kinase activity, have dramatically changed patients’s outcome and improved survival rate. Dormant CML-Leukemia Stem Cells (LSCs) are intrinsi

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7

Serra, Maria Margarida de Carvalho Negrão. "Process Engineering of Stem Cells for Clinical Application." Doctoral thesis, 2011. http://hdl.handle.net/10362/14140.

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Over the last decade, human embryonic stem cells (hESCs) have garnered a lot of attention owing to their inherent self-renewal ability and pluripotency. These characteristics have opened opportunities for potential stem cell-based regenerative medicines, for development of drug discovery platforms and as unique in vitro models for the study of early human development.(...)<br>Fundação para a Ciência e a Tecnologia

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8

Yeh, Chi-Jung, and 葉其鎔. "BASIC RESEARCH AND CLINICAL APPLICATION OF PERIPHERAL BLOOD STEM CELLS COLLECTION." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/99950645883131742558.

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碩士<br>高雄醫學大學<br>醫學研究所<br>88<br>Peripheral blood stem cells transplantation ( PBSCT ) has been used increasingly to treat various malignancies and has replaced autologous bone marrow transplantation ( Auto-BMT ) and allogeneic bone marrow transplantation ( Allo-BMT ), which has advantages over ABMT especially in terms of faster hematopoietic recovery, less tumor cells contamination and less side effects etc. The purpose of this study is to report our clinical experience to evaluate two different cells separator i.e. COBE Spectra and MCS3P in the efficiency of collecting stem cells. The correlat

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9

Wei, Sheng-Hsiu, and 魏聖修. "Clinical Application of Urinary Renal Tubular Epithelial Cells Examination in Nephropathy." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/6vb644.

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10

Huang, Min-hui, and 黃閔輝. "Application feasibility of optical micro-manipulation to single cells for clinical studies." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/09209105204762355141.

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碩士<br>中臺科技大學<br>醫學工程暨材料研究所<br>100<br>In this study, the manipulation characteristics of laser tweezers exerted at micro-sized particles are applied for investigating the feasibilities of clinical studies and examinations of single cells by trapping and dragging the experimental subjects: amniotic fluid cells (20 µm) and staphylococcus (1 µm). The experiments include (1) to collect the amniotic fluid cells which are put in the microfluidic chip for the cells separation: to investigate the practical operation parameters, i.e. laser power and dragging speed, in order to harmony with the real dra

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11

Simas, Margarida Alves. "Implementing Translational Steps for the Clinical Application of Stromal-Vascular Cells Spheroids." Master's thesis, 2019. https://hdl.handle.net/10216/121913.

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12

Cunha, Bárbara Martins Paiva da. "Development of integrated strategies for the downstream processing of human stem cells for clinical application." Doctoral thesis, 2016. http://hdl.handle.net/10362/20208.

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During the past decades, human stem cells (hSC) have emerged as a therapeutic alternative for several diseases. However, their clinical transfer still faces major challenges. Amongst them are the production of high cell amounts, the delivery of those high cell numbers at low volumes with minimal presence of residuals, while assuring the desired phenotype and function/potency. Although substantial efforts have been placed on the large-scale production of hSC and/or derivatives, the development of scalable approaches for downstream processing (DSP) of hSC and the establishment of fully integrat

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13

"Clinical application of adriamycin resistance screening and the in vitro effect of adriamycin on osteosarcoma cells." 1998. http://library.cuhk.edu.hk/record=b5889790.

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by To Siu Hang.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1998.<br>Includes bibliographical references (leaves 84-92).<br>Abstract also in Chinese.<br>Declaration --- p.i<br>Abstract --- p.ii<br>Acknowledgement --- p.vi<br>Abbreviations --- p.vii<br>List of Figures --- p.viii<br>List of Tables --- p.xii<br>Content --- p.xiv<br>Chapter 1. --- INTRODUCTION --- p.1<br>Chapter 1.1. --- Osteosarcoma --- p.1<br>Chapter 1.1.1. --- Incidence<br>Chapter 1.1.2. --- Age and Sex Distribution<br>Chapter 1.1.3. --- Clinical Features<br>Chapter 1.1.4. --- Treatment<br>Chapter 1.2. --- Ad

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14

Chen, Wen-Ting, та 陳文婷. "Structure–function characterization and clinical application of avian interleukin-1β and its impact on avian reovirus infected host cells". Thesis, 2014. http://ndltd.ncl.edu.tw/handle/9pr8g3.

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15

Wu, Shin-Yao, and 吳心耀. "Application of high efficient Self-assembled cell-array(SACA) chip and high speed automatic image capture system on clinical detection and analysis for circulating tumor cells." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/swc547.

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16

Pereira, João Miguel Calmeiro. "Potentiation of Dendritic Cell Phenotypic and Functional Characteristics for Application in Next-Generation Cancer Immunotherapy." Doctoral thesis, 2021. http://hdl.handle.net/10316/98749.

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Tese de Doutoramento em Ciências Farmacêuticas, na especialidade de Farmacologia e Farmacoterapia, apresentada à Faculdade de Farmácia da Universidade de Coimbra.<br>The field of cancer immunotherapy is growing at a fast pace, with new developments in this field leading to changes in cancer therapy. Dendritic cells (DCs) are immune cells with a key role at the interface of innate and adaptive immunity. DCs application in immunotherapy has been scrutinised and settled as highly desirable and full of translational and clinical potential, with around 400 clinical trials focused on anti-tumor DC v

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