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Relevant bibliographies by topics / Clinical research development

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Academic literature on the topic 'Clinical research development'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Clinical research development"

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Wolf, Myles. "Clinical Research Career Development." Academic Medicine 77, no. 11 (2002): 1084–88. http://dx.doi.org/10.1097/00001888-200211000-00004.

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Lenfant, Claude. "Clinical Research Skills Development." Circulation 105, no. 15 (2002): 1751–52. http://dx.doi.org/10.1161/01.cir.0000014122.41950.10.

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Pelusio, Rita M. "Clinical research in pharmaceutical development." Controlled Clinical Trials 18, no. 5 (1997): 461–63. http://dx.doi.org/10.1016/s0197-2456(97)00077-9.

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Holtzman, David M., Maria C. Carrillo, James A. Hendrix, et al. "Tau: From research to clinical development." Alzheimer's & Dementia 12, no. 10 (2016): 1033–39. http://dx.doi.org/10.1016/j.jalz.2016.03.018.

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McCormack, Brendan. "Clinical practice development." Journal of Research in Nursing 15, no. 2 (2010): 189–92. http://dx.doi.org/10.1177/1744987109357689.

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White, Edward. "Clinical practice development." Journal of Research in Nursing 15, no. 2 (2010): 101–3. http://dx.doi.org/10.1177/1744987109357823.

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Daniel-Ribeiro, Cláudio Tadeu. "Combination vaccines: development, clinical research and approval." Memórias do Instituto Oswaldo Cruz 95, no. 2 (2000): 279. http://dx.doi.org/10.1590/s0074-02762000000200025.

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Labianca, R., G. D. Beretta, S. Mosconi, M. A. Pessi, and L. Milesi. "The development of clinical research in CRC." Annals of Oncology 16 (May 2005): iv37—iv43. http://dx.doi.org/10.1093/annonc/mdi906.

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McNally, N. "Reforming clinical research and development in England." BMJ 327, no. 7414 (2003): 550–53. http://dx.doi.org/10.1136/bmj.327.7414.550.

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McSherry, Rob. "Research and Development in Clinical Nursing Practice." Clinical Effectiveness in Nursing 2, no. 3 (1998): 163–64. http://dx.doi.org/10.1016/s1361-9004(98)80021-6.

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Dissertations / Theses on the topic "Clinical research development"

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Lui, Wai-fan. "Clinical trials research methodology current practice in Hong Kong and training programme development /." Click to view the E-thesis via HKUTO, 1998. http://sunzi.lib.hku.hk/HKUTO/record/B38628582.

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Allwood, Brian. "A systematic review of the association between pulmonary tuberculosis and the development of chronic airflow obstruction in adults." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/10055.

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Includes abstract.<br>Includes bibliographical references.<br>Pulmonary tuberculosis (TB) as a cause of COPD is debated, with some, but not all evidence suggesting an association between the two conditions. Aim: To systematically review evidence for the association between pulmonary tuberculosis and the development of chronic obstructive pulmonary disease. We performed a systematic review of original English language, peer-reviewed literature using the PUBMED/MEDLINE database. Chronic Airflow Obstruction was defined on spirometric data (FEV1: FVC Ratio < 0.70; or FEV1: FVC Ratio < lower limit

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Silva, Ricardo Daniel da Conceição. "The clinical research coordination: the coordination of a clinical trial in a rare disease." Master's thesis, Universidade de Aveiro, 2016. http://hdl.handle.net/10773/18773.

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Mestrado em Biomedicina Farmacêutica<br>This thesis aims to describe the professional activity of a clinical research coordinator. More specifically, it intends to demonstrate the importance of its role in the context of new drug development through the example of the coordination of a clinical trial in a rare disease in a hospital. For this purpose, the drug development process will be addressed and it will also be discussed the current pharmaceutical research and development paradigm. The Portuguese clinical trial reality and development of new drugs for rare diseases will also be sc

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Wu, Jiandong. "Development of microfluidics-based neutrophil migration analysis systems for research and clinical applications." Royal Society of Chemistry, 2013. http://hdl.handle.net/1993/31179.

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Immune cell migration and chemotaxis plays a key role in immune response. Further research to study the mechanisms of immune cell migration and to develop clinical applications requires advanced experimental tools. Microfluidic devices can precisely apply chemical gradient signals to cells, which is advantageous in quantifying cell migratory response. However, most existing microfluidic systems are impractical to use without specialized facilities and research skills, which hinders their broad use in biological and medical research communities. In this thesis, we integrated several new develop

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Poupart, Alison. "The development and field test of a Mealtime Interaction Clinical Observation Tool : a pilot study and clinical research portfolio." Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7593/.

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Objective: The purpose of this study was to develop and test psychometric properties of a Mealtime Interaction Clinical Observation Tool (MICOT) that could be used to facilitate assessment and behavioural intervention in childhood feeding difficulties. Methods: Thematic analysis of four focus groups with feeding and behaviour experts identified the content and structure of the MICOT. Following refinement, inter-rater reliability was tested between three healthcare professionals. Results: Six themes were identified for the MICOT, which utilises a traffic-light system to identify areas of streng

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O'Connell, Jane. "An exploratory study for the development of emergency nurse practitioner specialist clinical practice standards." Thesis, Queensland University of Technology, 2014. https://eprints.qut.edu.au/73066/2/Jane_O%27Connell_Thesis.pdf.

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This thesis presents a mixed methods study to develop specialty specific clinical practice standards for Emergency Nurse Practitioners. This is the first time in Australia that Nurse Practitioners standards have been developed for a clinical specialty. These standards will guide educational preparation for the role and ongoing Continuous Professional Development for endorsed Emergency Nurse Practitioners.

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Löfqvist, Martin. "On the Valuation of ‘Big Pharma’s’ Research Pipelines." Thesis, Linköping University, Department of Management and Engineering, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-52502.

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<p>Background: Tougher demands from regulators on drugs efficiency and safety,governmental cost cutting and more complex areas of research, has led to that the importance of the pharmaceutical industry’s research pipelines are increasing. Even though the capital markets views on the pharmaceutical industry and its valuation is changing, the authors is not aware of any prior research that has been conducted on the topic of how the market reacts to clinical trial results or how security analysts valuates product pipelines.</p><p>Aim: This thesis aims to explain how security analysts valuate rese

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Rybchynski, Dawn. "Design of an artificial neural network research framework to enhance the development of clinical prediction models." Thesis, University of Ottawa (Canada), 2005. http://hdl.handle.net/10393/27027.

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This thesis presents an Artificial Neural Network Research Framework (ANN RFW) for predicting medical outcomes. The ANN RFW along with other new and pre-existing applications, and the steps linking them are presented as part of an Outcome Prediction Model Definition Process (OPMDP). Proof-of-concept experiments are performed on three outcomes from two Canadian Neonatal Network (CNN) databases. Successful results were obtained from the ANN RFW and a number of the subsequent applications. Results obtained using an ANN plus case based reasoner (CBR) were not yet favourable. In one of the intermed

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Balfour, Liezl. "Implementation and evaluation of a clinical pathway for non-invasive ventilation in critical care : a person-centred practice development approach." Thesis, University of Pretoria, 2020. http://hdl.handle.net/2263/79586.

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Introduction: Non-invasive ventilation (NIV) is an alternative method for providing safe mechanical ventilatory assistance to adult patients presenting with acute respiratory failure. Internationally the utilisation of NIV has increased by 400% during the past decade. The clinical pathway for NIV was collaboratively developed by the multidisciplinary team in the critical care unit in 2012, but implementation into practice did not realise as anticipated. As the burden of chronic disease rises in South Africa, the healthcare system is under pressure to provide evidence-based and costeffective ca

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Holloway, Kathryn. "Development and validation of a comprehensive assessment of combat experiences to facilitate research on veterans' post-combat psychological health." Thesis, Alliant International University, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3714885.

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<p> Following more than decade of U.S. military operations in the in the Middle East, it is important to understand the impact of prolonged combat operations on the wellbeing of Veterans. To understand this relationship accurately we must have access to reliable and valid measures of combat exposure. A meta-analysis of research with combat Veterans found relatively few studies adequately assessed nature and extent of Veteran’s combat experiences (Institute of Medicine, 2008). </p><p> The purpose of this research was to develop a more comprehensive measure of combat exposure for use in

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Books on the topic "Clinical research development"

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Steiner, Janice. Clinical development: Strategic, pre-clinical, clinical, and regulatory issues. Interpharm Press, 1997.

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A, Eugster Erica, and Pescovitz Ora Hirsch, eds. Developmental endocrinology: From research to clinical practice. Humana Press, 2002.

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A, Eugster Erica, and Pescovitz Ora Hirsch, eds. Developmental endocrinology: From research to clinical practice. Humana Press, 2002.

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H, Roe Brenda, and Webb Christine, eds. Research and development in clinical nursing practice. Whurr Publishers, 1998.

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Roe, Brenda, and Christine Webb, eds. Research and Development in Clinical Nursing Practice. Whurr Publishers Ltd, 1998. http://dx.doi.org/10.1002/9780470699270.

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W, Ellis Ronald, ed. Combination vaccines: Development, clinical research, and approval. Humana Press, 1999.

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Kshirsagar, Nilima. Regulatory requirements for drug development and clinical research. Indian Council of Medical Research, 2013.

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1953-, Rose Klaus, and Van den Anker, John N., eds. Guide to paediatric drug development and clinical research. Karger, 2010.

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Cocchetto, David M. Managing the clinical drug development process. Dekker, 1992.

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Cocchetto, David M. Managing the clinical drug development process. Dekker, 1992.

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Book chapters on the topic "Clinical research development"

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Hale, Gregory A., and Jennifer Pullum. "Clinical Research Organizations." In Pediatric Cancer Therapeutics Development. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-06357-2_8.

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La Montagne, John R., and George T. Curlin. "Vaccine Clinical Trials." In Vaccine Research and Development. CRC Press, 2024. http://dx.doi.org/10.1201/9781003573838-10.

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Broekman, M. L. D. "Ethics of Clinical Research." In Learning and Career Development in Neurosurgery. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-02078-0_9.

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Young, Jonathan C., and Lori Nesbitt. "Ethical Concerns in Clinical Research." In Drug Discovery and Development. CRC Press, 2019. http://dx.doi.org/10.1201/9781315113470-20.

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Oliverio, Alberto. "Clinical Psychopharmacology: Research and Development." In Neurosciences and Ethics. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73570-7_18.

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Ghatta, Srinivas, and Michelle Niewood. "Clinical Research in Pharmaceutical Drug Development." In Drug Discovery and Development. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-5534-3_14.

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Erceg, Damir. "Pharmacogenomics in Drug Research and Development." In Pharmacogenomics in Clinical Practice. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-45903-0_24.

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Holmes, Laurens. "Clinical research proposal development and protocol." In Applied Epidemiologic Principles and Concepts, 2nd ed. CRC Press, 2017. http://dx.doi.org/10.4324/9781315369761-3.

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Holmes, Laurens. "Clinical research proposal development and protocol." In Applied Epidemiologic Principles and Concepts. CRC Press, 2017. http://dx.doi.org/10.1201/9781315369761-3.

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Wøien, Hilde, and Sigrid Rannem. "Research Development in the Clinical Field." In Leadership in Nursing: Experiences from the European Nordic Countries. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-10964-6_15.

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Conference papers on the topic "Clinical research development"

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Periyasamy, Madhavan. "Integrating Machine Learning in Pre-Clinical Research for Predictive Analytics in Drug Development." In 2024 First International Conference for Women in Computing (InCoWoCo). IEEE, 2024. https://doi.org/10.1109/incowoco64194.2024.10863152.

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Grīnblate, Silva, and Aija Ilgaža. "Clinical symptoms and sex steroid measurements in domestic ferrets (Mustela putorius furo) with hyperadrenocorticism." In Research for Rural Development, 2017. Latvia University of Agriculture, 2017. http://dx.doi.org/10.22616/rrd.23.2017.041.

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"AN ONTOLOGY FOR SUPPORTING CLINICAL RESEARCH ON CERVICAL CANCER." In International Conference on Knowledge Engineering and Ontology Development. SciTePress - Science and and Technology Publications, 2009. http://dx.doi.org/10.5220/0002265701030108.

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Chelsom, John J., Ron Summers, Ira Pande, and Ian Gaywood. "Ontology-driven development of a clinical research information system." In 2011 24th International Symposium on Computer-Based Medical Systems (CBMS). IEEE, 2011. http://dx.doi.org/10.1109/cbms.2011.5999165.

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Soliman, Alaa, Shane Pawluk, Kyle Wilby, and Ousama Rachid. "Strengthening the Quality of Clinical Pharmacokinetic studies: Development and Validation of a Critical Appraisal Tool for Clinical Pharmacokinetic Research." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0177.

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Background: Robust critical appraisal tools for pharmacokinetic studies are lacking. The aim of this study is to develop a valid and reliable critical appraisal tool for clinical pharmacokinetic studies. Methodology: A systematic review was conducted through Embase and Pubmed to identify quality markers of clinical pharmacokinetic studies. Quality-related questions were formulated to help in appraising pharmacokinetic studies. Experts were approached to participate in a modified Delphi process to achieve their consensus regarding the formulated questions based on percentage of agreement betwee

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Singh, Prashant, and Diana J. Wilkie. "Development of Advanced Clinical Research Application: PAINRelieveIt using Patient Feedback." In 2019 IEEE International Conference on Electrical, Computer and Communication Technologies (ICECCT). IEEE, 2019. http://dx.doi.org/10.1109/icecct.2019.8869466.

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Abdalla, Tasneem Ibrahim, Shiemaa Sidahmed Awad, and Sharief F. Babiker. "Transmission of real-time clinical diagnostic signals over the GSM network." In 2011 IEEE Student Conference on Research and Development (SCOReD). IEEE, 2011. http://dx.doi.org/10.1109/scored.2011.6148722.

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MacAvaney, Sean, Sajad Sotudeh, Arman Cohan, Nazli Goharian, Ish Talati, and Ross W. Filice. "Ontology-Aware Clinical Abstractive Summarization." In SIGIR '19: The 42nd International ACM SIGIR Conference on Research and Development in Information Retrieval. ACM, 2019. http://dx.doi.org/10.1145/3331184.3331319.

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Wang, Yixin. "Molecular characterization of cancer: Research tools or clinical diagnostics?" In AACR International Conference: Molecular Diagnostics in Cancer Therapeutic Development– Sep 27-30, 2010; Denver, CO. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/diag-10-ed3a-2.

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Harbuz, Vitalii. "TUR SYNDROME. RELEVANCE. MECHANISM OF DEVELOPMENT. CLINICAL PICTURE. DIAGNOSIS AND TREATMENT. PREVENTION." In SCIENTIFIC PRACTICE: MODERN AND CLASSICAL RESEARCH METHODS, chair Yuliya Ploshchenko and Olha Stanislavivna. European Scientific Platform, 2023. http://dx.doi.org/10.36074/logos-26.05.2023.099.

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Reports on the topic "Clinical research development"

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Vagnoni, Cristiana. COVID-19 vaccines: July update on research. Parliamentary Office of Science and Technology, 2020. http://dx.doi.org/10.58248/rr35.

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There are almost 150 coronavirus vaccine candidates under development. Only 19 of these are now being tested in humans. Many types of vaccines are rapidly progressing through clinical trials. Only two vaccine candidates have announced large scale Phase 3 trials, involving several thousands of people. Only one candidate has been approved for restricted human use. Measuring a reduction in COVID-19 levels is an obstacle for Phase 3 clinical trials, as they require a high infection rate among the tested population to prove vaccine efficacy. International agreements with countries where SARS-CoV-2

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Gao, Yicheng, Zhihan Liu, Rui Cao, et al. Knee osteoarthritis clinical practice guidelines should pay more attention to identify and report research priorities to increase research value and decrease waste: a systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.4.0063.

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Review question / Objective: Clinical practice guideline development group systematic summary of research evidence, so they have the most capacity and energy to identify research priorities. We systematically evaluated the reporting form and content of research priorities in clinical practice guidelines (CPGs) related to knee osteoarthritis (KOA). Information sources: We searched 6 databases including PubMed, Embase, VIP Database for Chinese Technical Periodicals, Wanfang, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure. In addition, The official websites of

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Zhu, Wenhao, Xing Ding, Jiale Zheng, et al. Characteristics, Treatment, and Research Development of Bertolotti’s Syndrome: A Bibliometric Analysis and Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.1.0077.

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Review question / Objective: Bertolotti’s syndrome is a prevalent congenital deformity. However, many physicians fail to include it in their differential diagnosis for low back pain, which results in missed diagnosis or misdiagnosis. There is still a lack of standardized treatment and management strategies for Bertolotti’s syndrome. This study aimed to review the clinical characteristics and management of Bertolotti’s syndrome and reports bibliometric insights in advancements in Bertolotti’s syndrome research. Information sources: A thorough literature search of the PubMed, Embase, Medline, Sc

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Wang, Hao, and Yulai Xu. Chemopreventive Effects of Immunotrophic Preparations in the Development of Prostate Cancer: A Network Meta-Analysis of Randomized Controlled Trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.8.0037.

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Review question / Objective: After successful treatment with ADT, most patients with advanced disease eventually develop resistance and progress to castration-resistant PCa (CRPC), which remains an incurable disease.Low survival and high mortality of PCa are associated with the appearance of CRPC and subsequent metastatic disease. To advance the fight against PCa, it is necessary to continue basic and clinical research to improve testing, prevention and treatment practices. However, under current treatments, prevention should be seen as a basic strategy to reduce PCa morbidity and mortality. E

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Tourassi, Georgia, and Joseph Lake. Cooperative Research and Development Agreement With Georgetown University Report: National Institutes of Health, National Center for Advancing Translational Sciences Clinical and Translational Science Award. Office of Scientific and Technical Information (OSTI), 2020. http://dx.doi.org/10.2172/1675040.

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Lavadenz, Magaly, Elvira Armas, and Natividad Robles. Bilingual Teacher Residency Programs in California: Considerations for Development and Expansion. Loyola Marymount University, 2019. http://dx.doi.org/10.15365/ceel.policy.7.

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Public interest, research and policies about dual language education and the multiple benefits of bilingualism and biliteracy have led to shortages of bilingual education teachers in the state and nation. School districts and educator preparation programs are actively looking for pathways of bilingual teacher preparation to meet local demands for more dual language programs. Modeled after medical residencies, teacher residencies are deeply rooted in clinical training, typically placing residents in classrooms with experienced teachers in high-needs schools where they are supported in their dev

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Bellissant, Eric, Isabelle Boutron, Carole Chapin, et al. Ensuring that the results of all clinical trials in France are posted. Ministère de l’enseignement supérieur et de la recherche, 2025. https://doi.org/10.52949/56.

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The Working Group on “Transparency and the publicising of the results of health research”, was appointed by the French Ministry in charge of Research, in conjunction with the French Ministry in charge of Health. It seeks to address the problem of publication bias, which is the tendency to prioritise the publication of positive results. However, if they are based on an incomplete, skewed understanding of research results, this bias may result in erroneous health policy decisions. This report makes recommendations towards all stakeholders involved in clinical research, and covers the entire scie

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Ren, Ying, Jiange Zhang, Ranjun Zhu, et al. How to implement “usual care”: a protocol for an overview of systematic reviews. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.4.0029.

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Review question / Objective: “Usual care” is changing all the time whether in clinical practice or experimental research, the scope of usual care is constantly updated by adding new contents. However, the composition of usual care is still unclear, and there is no formal description to confirm whether the nursing contents are in line with usual care’ requirements. The goal was to review existing or not published but completed SRs about UC’s elements to gather the evidence about: a What’s the development routine of UC in diverse field. b The similarities and differences of different UC. c The s

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Chen, Yuqi. Efficacy of acupuncture treatment for ovulatory disorder infertility A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.4.0088.

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Review question / Objective: Efficacy of Acupuncture for ovulatory disorder infertility: A Systematic Review and Meta-Analysis of randomized controlled trials. Condition being studied: Those who do not have contraception after marriage, have a normal sexual life, and cohabitation for 1 year without pregnancy are called infertility, and those who have no history of pregnancy are called primary infertility. Those with a history of previous pregnancy are called secondary infertility. Infertility is a global reproductive health problem that affects about 10% of married women. Ovulatory infertility

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Leavy, Michelle B., Costas Boussios, Robert L. Phillips, Jr., et al. Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression: Final Report. Agency for Healthcare Research and Quality (AHRQ), 2022. http://dx.doi.org/10.23970/ahrqepcwhitepaperdepressionfinal.

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Objective. The objective of this project was to demonstrate the feasibility and value of collecting harmonized depression outcome measures in the patient registry and health system settings, displaying the outcome measures to clinicians to support individual patient care and population health management, and using the resulting measures data to support patient-centered outcomes research (PCOR). Methods. The harmonized depression outcome measures selected for this project were response, remission, recurrence, suicide ideation and behavior, adverse effects of treatment, and death from suicide. T

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