Academic literature on the topic 'Clinical trials'

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Journal articles on the topic "Clinical trials"

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Vulto, Arnold G. "Clinical trials on trial." European Journal of Hospital Pharmacy 19, no. 4 (2012): 347. http://dx.doi.org/10.1136/ejhpharm-2012-000180.

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Patel, Khushru. "Envisioning Data in Clinical Trials." International Journal of Science and Research (IJSR) 11, no. 9 (2022): 1068. http://dx.doi.org/10.21275/sr22926130141.

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Santhosh R Divya, Samuel. "In Silico Clinical Trials - Review." International Journal of Science and Research (IJSR) 12, no. 6 (2023): 262–66. http://dx.doi.org/10.21275/sr23512133636.

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Dmitrienko, Alex, Gautier Paux, and Thomas Brechenmacher. "POWER CALCULATIONS IN CLINICAL TRIALS WITH COMPLEX CLINICAL OBJECTIVES." Journal of the Japanese Society of Computational Statistics 28, no. 1 (2015): 15–50. http://dx.doi.org/10.5183/jjscs.1411001_213.

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Harman, Chloë. "Putting clinical trials on trial." Nature Reviews Nephrology 5, no. 6 (2009): 301. http://dx.doi.org/10.1038/nrneph.2009.89.

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Bousquet, Philippe Jean, Pascal Demoly, Giovanni Passalacqua, G. Walter Canonica, and Jean Bousquet. "Immunotherapy: clinical trials – optimal trial and clinical outcomes." Current Opinion in Allergy and Clinical Immunology 7, no. 6 (2007): 561–66. http://dx.doi.org/10.1097/aci.0b013e3282f1d6a4.

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Kumar, Prashant. "Decentralized Clinical Trials - Need, Challenges and Prospects." International Journal of Science and Research (IJSR) 11, no. 9 (2022): 502–4. http://dx.doi.org/10.21275/sr22908131821.

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Gnanasambandam, Anjali. "Artificial Intelligence in Clinical Trials- Future Prospectives." Bioequivalence & Bioavailability International Journal 7, no. 1 (2023): 1–8. http://dx.doi.org/10.23880/beba-16000196.

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Clinical trials are essential for delivering novel medications, technology, and procedures to the market and clinical practice. Only 10% of these studies complete the entire procedure from the drug design to the four phases of development, because clinical trials are becoming more expensive and difficult to perform. The population's health, standard treatment, health economics, and sustainability suffered greatly from this low completion rate. Artificial intelligence (AI) is one of the tools that could streamline some of the processes which are the most tedious operations, like patient selecti
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Mugosa, Snezana, and Anja Glusica. "Clinical trials challenges - impact of the new clinical trial regulation on the conduct of clinical trials." Vojnosanitetski pregled, no. 00 (2021): 61. http://dx.doi.org/10.2298/vsp200316061m.

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Weinberg, Jeffrey. "Clinical Trials in Progress: ROADS Trial." ONCOLOGY, no. 3508 (August 2021): 495. http://dx.doi.org/10.46883/onc.2021.3508.0495.

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Phase 3 Randomized Controlled Trial of Post-Surgical Stereotactic Radiotherapy (SRT) versus Surgically Targeted Radiation Therapy (STaRT) with GammaTile for Treatment of Newly Diagnosed Metastatic Brain Tumors (ROADS; NCT04365374).
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Dissertations / Theses on the topic "Clinical trials"

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Kim, Anne(Anne Y. ). "Optimizing clinical trials with Open Trial Chain." Thesis, Massachusetts Institute of Technology, 2018. https://hdl.handle.net/1721.1/121787.

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Thesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2019<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references (pages 59-64).<br>The objective of this thesis is to study the challenges of data sharing in healthcare (namely clinical trials), and propose the use of Open Algorithms (OPAL) as a viable solution for research collaboration that allows for access to data without compromising data ownership (data is only used once for the intended purpose, raw data is never leaked, the value gener
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Vickers, Andrew J. "Homoeopathy and clinical trials." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302395.

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Zhang, Yifan. "Bayesian Adaptive Clinical Trials." Thesis, Harvard University, 2014. http://nrs.harvard.edu/urn-3:HUL.InstRepos:13070079.

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Bayesian adaptive designs are emerging as popular approach to develop adaptive clinical trials. In this dissertation, I describe the mathematical steps for computing the theoretical optimal adaptive designs in biomarker-integrated trials and in trials with survival outcomes. Section 1 discusses the optimal design in personalized medicine. The optimal design maximizes the expected trial utility given any pre-specified utility function, though the discussion here focuses on maximizing responses within a given patient horizon. This work provides absolute benchmark for the evaluation of trial des
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Scarale, M. G. "RESPONSE - ADAPTIVE CLINICAL TRIALS." Doctoral thesis, Università degli Studi di Milano, 2015. http://hdl.handle.net/2434/344736.

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The question we posed at the beginning of this thesis was whether, in the presence of a clinical superiority of one of two possible treatments, it was possible to find an appropriate statistical methodology that would allow us to reach this goal. We were thus led to explore many possibilities to carry out this analysis and randomly assign patients to the two treatments, as required by the particular nature of these experiments. Specifically, we made a close examination of the methods of randomization, especially appreciating the flexibility of the adaptive responses, and could see the strength
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Lui, Wai-fan. "Clinical trials research methodology current practice in Hong Kong and training programme development /." Click to view the E-thesis via HKUTO, 1998. http://sunzi.lib.hku.hk/HKUTO/record/B38628582.

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Čekanauskaitė, Asta. "Informedness about clinical trials of patients participating in placebo-controlled clinical trials in Lithuania." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20130114_081952-77101.

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The dissertation aims to analyse the problem of informed consent in clinical drug trials. Understanding of the provided information is one of the basic components of a person’s sound and informed decision to participate in a clinical trial. Our research evaluated informedness about clinical trials of patients participating in clinical drug trials in Lithuania, with emphasis on the informedness about key elements of clinical trial design (placebo-control, double-blindness, and randomisation). An anonymous survey of patients participating in clinical drug trials was conducted for the purposes of
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Kehl, Victoria. "Responder Identification in Clinical Trials." Diss., lmu, 2002. http://nbn-resolving.de/urn:nbn:de:bvb:19-5908.

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Sydow, Victoria. "Clinical Trials - Competitive resource management." Thesis, KTH, Skolan för bioteknologi (BIO), 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-149476.

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Murphy, Jeremy James. "Clinical trials in cerebrovascular disease." Thesis, University of Nottingham, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293328.

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Machin, David. "Statistical aspects of clinical trials." Thesis, University of Southampton, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.257667.

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Books on the topic "Clinical trials"

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Piantadosi, Steven. Clinical Trials. John Wiley & Sons, Inc., 2005. http://dx.doi.org/10.1002/0471740136.

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Pocock, Stuart J. Clinical Trials. John Wiley & Sons Ltd,., 2013. http://dx.doi.org/10.1002/9781118793916.

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Pawlik, Timothy M., and Julie A. Sosa, eds. Clinical Trials. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-35488-6.

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Mantel, Barbara. Clinical Trials. CQ Press, 2018. http://dx.doi.org/10.4135/cqresrre20180518.

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Lelia, Duley, and Farrell Barbara 1946-, eds. Clinical trials. BMJ Books, 2002.

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Rabinarayan, Dash. Clinical trials. Studera Press, 2017.

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Kelly, William Kevin, and Susan Halabi, eds. Oncology Clinical Trials. Springer Publishing Company, 2018. http://dx.doi.org/10.1891/9780826168733.

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Kerr, David J., Kirstine Knox, Diane C. Robertson, Derek Stewart, and Rene Watson, eds. Clinical Trials Explained. Blackwell Publishing Ltd, 2006. http://dx.doi.org/10.1002/9780470750612.

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Machin, David, and Peter M. Fayers. Randomized Clinical Trials. John Wiley & Sons, Inc., 2010. http://dx.doi.org/10.1002/9780470686232.

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Meinert, Curtis L. Clinical Trials Dictionary. John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118315293.

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Book chapters on the topic "Clinical trials"

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Patra, Jayanta Kumar, Swagat Kumar Das, Gitishree Das, and Hrudayanath Thatoi. "Clinical Trials." In A Practical Guide to Pharmacological Biotechnology. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-6355-9_6.

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Basu, Bikramjit, and Sourabh Ghosh. "Clinical Trials." In Biomaterials for Musculoskeletal Regeneration. Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-3017-8_9.

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McKneally, M. F., B. McPeek, F. Mosteller, and E. A. M. Neugebauer. "Clinical Trials." In Surgical Research. Springer New York, 1998. http://dx.doi.org/10.1007/978-1-4612-1888-3_26.

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Rhoads, Kim F., and Julio E. Garcia-Aguilar. "Clinical Trials." In Transanal Endoscopic Microsurgery. Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-76397-2_13.

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Staquet, M. "Clinical Trials." In Surgical Oncology. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-72646-0_43.

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Chen, Donna T. "Clinical Trials." In Encyclopedia of Women’s Health. Springer US, 2004. http://dx.doi.org/10.1007/978-0-306-48113-0_91.

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Hay, Annette E., Lorna Fern, Ralph M. Meyer, Nita Seibel, and Ronald Barr. "Clinical Trials." In Cancer in Adolescents and Young Adults. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-33679-4_21.

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Rudge, Peter. "Clinical Trials." In Multiple Sclerosis Research in Europe. Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4143-4_2.

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Cohen, Margo Panush. "Clinical Trials." In The Polyol Paradigm and Complications of Diabetes. Springer New York, 1987. http://dx.doi.org/10.1007/978-1-4612-4670-1_7.

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Zanders, Edward D. "Clinical Trials." In The Science and Business of Drug Discovery. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-57814-5_12.

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Conference papers on the topic "Clinical trials"

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Salve, Yash, Gaurav Mude, Purva Tarale, and Rajat Mahajan. "Telemedicine and Remote Clinical Trials: Revolutionizing Healthcare Research." In 2024 International Conference on Healthcare Innovations, Software and Engineering Technologies (HISET). IEEE, 2024. http://dx.doi.org/10.1109/hiset61796.2024.00043.

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Shetty S, Shailesh, and Pushpalatha K. "A Survey on Clinical Trials Using Blockchain Technology." In 2024 International Conference on Computing, Semiconductor, Mechatronics, Intelligent Systems and Communications (COSMIC). IEEE, 2024. https://doi.org/10.1109/cosmic63293.2024.10871564.

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Narayan, Sakkeri Shashank, Namani Deepika Rani, Mohammed Faizan, Madhastu Bhavana, Sanagala Vishwanath, and Vikram Tamagonda. "OPTIPICK: Streamlining Participant Selection for Vital Clinical Trials." In 2025 International Conference on Ambient Intelligence in Health Care (ICAIHC). IEEE, 2025. https://doi.org/10.1109/icaihc64101.2025.10957207.

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Koulizakos, Stavros, Tina Kjellén, Karin Mellgren, and Jenny M. Kindblom. "2 Pediatric clinical trials need pediatric clinical trial budgets." In Prague 2023. 20th ESDPPP congress hosted by Prague, CZ. Our societies 20th conference and 35th anniversary. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/bmjpo-2024-esdppp.2.

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Hilsenbeck, S., and M. Piccart. "Clinical Trials 102: New Strategies in Targeted Therapy Clinical Trials." In Abstracts: Thirty-Second Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 10‐13, 2009; San Antonio, TX. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.sabcs-09-es5-1.

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Cameron, Fraser, Nihat Baysal, and B. Wayne Bequette. "A differential simulator using past clinical trial data to run simulated clinical trials." In 2015 American Control Conference (ACC). IEEE, 2015. http://dx.doi.org/10.1109/acc.2015.7172135.

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"Feasibility Estimation for Clinical Trials." In International Conference on Health Informatics. SCITEPRESS - Science and and Technology Publications, 2014. http://dx.doi.org/10.5220/0004795500680077.

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Kiekens, Kelli C., Dominique Galvez, Gabriela Romano, Ricky Cordova, and Jennifer K. Barton. "Falloposcope Modifications for Clinical Trials." In CLEO: Applications and Technology. OSA, 2020. http://dx.doi.org/10.1364/cleo_at.2020.am4i.5.

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Summers, Ron, Hiten Vyas, Nilesh Dudhal, Neil F. Doherty, Crispin R. Coombs, and Mark Hepworth. "Innovations in clinical trials informatics." In 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2008. http://dx.doi.org/10.1109/iembs.2008.4649806.

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Bhati, D. K. "Informatics in clinical trials: Evidences from Clinical Data Management." In 2013 Indian Conference on Medical Informatics and Telemedicine (ICMIT). IEEE, 2013. http://dx.doi.org/10.1109/indiancmit.2013.6529402.

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Reports on the topic "Clinical trials"

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Border, Peter, and Samuel Bunce. Regulating Clinical Trials. Parliamentary Office of Science and Technology, 2017. http://dx.doi.org/10.58248/pn561.

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Kaplan, Celia P. Minorities in Clinical Trials: Patients, Physicians, Clinical Trial Characteristics, and Their Environment. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada542448.

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Kaplan, Celia. Minorities and Clinical Trials: Patients, Physicians, Clinical Trial Characteristics, and Their Environment. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada573587.

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Kaplan, Celia P. Minorities and Clinical Trials: Patients, Physicians, Clinical Trial Characteristics and their Environment. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada586285.

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Keenan, Teresa A., and Chuck Rainville. AARP Clinical Trials Survey: Annotated Questionnaire. AARP Research, 2023. http://dx.doi.org/10.26419/res.00709.002.

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Lefebvre, Carol, and Julie Glanville. Identifying Unpublished Clinical Trial Data for Evidence Syntheses. Instats Inc., 2023. http://dx.doi.org/10.61700/txz8zyhloguql469.

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This workshop provides an overview of identifying clinical trials and trial results for systematic reviews and other evidence syntheses. It covers sources such as trials / trials results registers, regulatory agency sources, and other novel resources. Participants will learn how to search the above sources, how to manage search results and report their searches. An official Instats certificate of completion and 1 ECTS Equivalent point is provided at the conclusion of the seminar.
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Kaplan, Celia P. Inclusion of Minority Patients in Breast Cancer Clinical Trials: The Role of the Clinical Trial Environment. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada485604.

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Kaplan, Celia P. Inclusion of Minority Patients in Breast Cancer Clinical Trials: The Role of the Clinical Trial Environment. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada509888.

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Kaplan, Celia P. Inclusion of Minority Patients in Breast Cancer Clinical Trials: The Role of the Clinical Trial Environment. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada544195.

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Zhang, Cheng, and Yue Yang. Impact of adaptive design on reducing the duration of clinical trials in rare cancers: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.2.0081.

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Review question / Objective: Whether the application of adaptive design in clinical trials of rare cancers can shorten the duration of clinical trials? Condition being studied: Currently, the development of innovative drug products (InMPs) for rare cancers faces many challenges, including the difficulty of enrolling sufficient numbers of patients from small and heterogeneous patient populations for clinical trials, and the significant risks of high financial investment, long development times and potential failure from a pharmaceutical company's perspective for rare cancer drugs due to limited
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