Academic literature on the topic 'Clock-transitions'

Weighted finite automata (WFA) are used with FPGA accelerating hardware to scan large genomic banks. Hardwiring such automata raises surface area and clock frequency constraints, requiring efficient ∊-transitions-removal techniques. In this paper, we present bounds on the number of new transitions for the development of acyclic WFA, which is a special case of the ∊-transitions-removal problem. We introduce a new problem, a partial removal of ∊-transitions while accepting short chains of ∊-transitions.

The issue of what starts the circadian clock ticking was addressed by studying the developmental appearance of the daily rhythm in the expression of two genes in the zebrafish pineal gland that are part of the circadian clock system. One encodes the photopigment exorhodopsin and the other the melatonin synthesizing enzyme arylalkylamine N-acetyltransferase (AANAT2). Significant daily rhythms in AANAT2 mRNA abundance were detectable for several days after fertilization in animals maintained in a normal or reversed lighting cycle providing 12 h of light and 12 h of dark. In contrast, these rhythms do not develop if animals are maintained in constant lighting or constant darkness from fertilization. In contrast to exorhodopsin, rhythmicity of AANAT2 can be initiated by a pulse of light against a background of constant darkness, by a pulse of darkness against a background of constant lighting, or by single light-to-dark or dark-to-light transitions. Accordingly, these studies indicate that circadian clock function in the zebrafish pineal gland can be initiated by minimal photic cues, and that single photic transitions can be used as an experimental tool to dissect the mechanism that starts the circadian clock in the pineal gland.