Relevant bibliographies by topics / Clonal hematopoiesis of indeterminate potential

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Clonal hematopoiesis of indeterminate potential'

Author: Grafiati
Published: 25 January 2025
Last updated: 31 July 2025

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Journal articles on the topic "Clonal hematopoiesis of indeterminate potential"

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Papa, Veronica, Luisa Marracino, Francesca Fortini, et al. "Translating Evidence from Clonal Hematopoiesis to Cardiovascular Disease: A Systematic Review." Journal of Clinical Medicine 9, no. 8 (2020): 2480. http://dx.doi.org/10.3390/jcm9082480.

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Some random mutations can confer a selective advantage to a hematopoietic stem cell. As a result, mutated hematopoietic stem cells can give rise to a significant proportion of mutated clones of blood cells. This event is known as “clonal hematopoiesis.” Clonal hematopoiesis is closely associated with age, and carriers show an increased risk of developing blood cancers. Clonal hematopoiesis of indeterminate potential is defined by the presence of clones carrying a mutation associated with a blood neoplasm without obvious hematological malignancies. Unexpectedly, in recent years, it has emerged
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Steensma, David P. "Clinical consequences of clonal hematopoiesis of indeterminate potential." Blood Advances 2, no. 22 (2018): 3404–10. http://dx.doi.org/10.1182/bloodadvances.2018020222.

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Abstract Clonally restricted hematopoiesis is a common aging-associated biological state that predisposes to subsequent development of a hematological malignancy or cardiovascular death. Clonal expansion driven by leukemia-associated somatic mutations, such as DNMT3A, ASXL1, or TET2, is best characterized, but oligoclonality can also emerge without recognized leukemia-driver mutations, perhaps as a result of stochastic neutral drift. Murine models provide compelling evidence that a major mechanism of increased cardiovascular mortality in the context of clonal hematopoiesis is accelerated ather
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Steensma, David P. "Clinical consequences of clonal hematopoiesis of indeterminate potential." Hematology 2018, no. 1 (2018): 264–69. http://dx.doi.org/10.1182/asheducation-2018.1.264.

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Abstract Clonally restricted hematopoiesis is a common aging-associated biological state that predisposes to subsequent development of a hematological malignancy or cardiovascular death. Clonal expansion driven by leukemia-associated somatic mutations, such as DNMT3A, ASXL1, or TET2, is best characterized, but oligoclonality can also emerge without recognized leukemia-driver mutations, perhaps as a result of stochastic neutral drift. Murine models provide compelling evidence that a major mechanism of increased cardiovascular mortality in the context of clonal hematopoiesis is accelerated ather
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Boettcher, Steffen, and Benjamin L. Ebert. "Clonal Hematopoiesis of Indeterminate Potential." Journal of Clinical Oncology 37, no. 5 (2019): 419–22. http://dx.doi.org/10.1200/jco.2018.79.3588.

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Steensma, David P., Rafael Bejar, Siddhartha Jaiswal, et al. "Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes." Blood 126, no. 1 (2015): 9–16. http://dx.doi.org/10.1182/blood-2015-03-631747.

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Abstract Recent genetic analyses of large populations have revealed that somatic mutations in hematopoietic cells leading to clonal expansion are commonly acquired during human aging. Clonally restricted hematopoiesis is associated with an increased risk of subsequent diagnosis of myeloid or lymphoid neoplasia and increased all-cause mortality. Although myelodysplastic syndromes (MDS) are defined by cytopenias, dysplastic morphology of blood and marrow cells, and clonal hematopoiesis, most individuals who acquire clonal hematopoiesis during aging will never develop MDS. Therefore, acquisition
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Ramdohr, Florian, Astrid Monecke, Madlen Jentzsch, et al. "Extramedullary Clonal Hematopoiesis with Indeterminate Potential." Clinical Lymphoma Myeloma and Leukemia 21, no. 9 (2021): e696-e698. http://dx.doi.org/10.1016/j.clml.2021.04.008.

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Libby, Peter, and Benjamin L. Ebert. "CHIP (Clonal Hematopoiesis of Indeterminate Potential)." Circulation 138, no. 7 (2018): 666–68. http://dx.doi.org/10.1161/circulationaha.118.034392.

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Testa, Ugo, Germana Castelli, and Elvira Pelosi. "CLONAL HEMATOPOIESIS: ROLE IN HEMATOLOGIC NON-HEMATOLOGIC." Mediterranean Journal of Hematology and Infectious Diseases 14, no. 1 (2022): e2022069. http://dx.doi.org/10.4084/mjhid.2022.069.

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Hematopoietic stem cells (HSCs) ensure the coordinated and balanced production of all hematopoietic cell types throughout life. Aging is associated with a gradual decline of the self-renewal and regenerative potential of HSCs and with the development of clonal hematopoiesis. Clonal hematopoiesis of indeterminate potential (CHIP) is a term defining the clonal expansion of genetically variant hematopoietic cells bearing one or more gene mutations and/or structural variants (such as copy number alterations). CHIP increases exponentially with age and is associated with cancers, including hematolog
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Nardi, Valentina, Frank C. Kuo, and Robert P. Hasserjian. "Premalignant Clonal Hematopoietic Proliferations." American Journal of Clinical Pathology 152, no. 3 (2019): 347–58. http://dx.doi.org/10.1093/ajcp/aqz079.

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AbstractObjectivesThe 2017 Workshop of the Society for Hematopathology/European Association for Hematopathology aimed to review premalignant clonal hematopoietic proliferations.MethodsThe workshop panel reviewed 27 cases of clonal proliferations of indeterminate significance or potential (18 myeloid, nine lymphoid) and rendered consensus diagnoses.ResultsImmunophenotyping and genetic studies on peripheral blood, bone marrow, and lymph node samples have led to the incidental detection of small clonal populations in asymptomatic individuals. These premalignant clonal myeloid and lymphoid prolife
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Sleptsov, A. A., M. S. Nazarenko, and V. Р. Puzyrev. "Common in atherogenesis and carcinogenesis: clonal hematopoiesis." Russian Journal of Cardiology 28, no. 10 (2023): 5511. http://dx.doi.org/10.15829/1560-4071-2023-5511.

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Clonal hematopoiesis is a common age-dependent state accompanied by the expansion of mutant hematopoietic stem cells as a result of somatic mutations and is associated with a high risk of hematopoietic neoplasms and cardiovascular diseases. Clonal hematopoiesis in human ontogenesis occurs asymptomatically, and the fraction of mutant clones can exceed more than 2% of the total pool of circulating nucleated blood cells by age 70. Due to the variability of the accumulation rate of mutant clones, signs of clonal hematopoiesis can be observed at a younger age. Clonal hematopoiesis may act as a beni
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Dissertations / Theses on the topic "Clonal hematopoiesis of indeterminate potential"

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Dufossée, Mélody. "Rôle des Hématopoïèses clonales de potentiel indéterminé (CHIP) dans la physiopathologie des maladies cardiovasculaires." Electronic Thesis or Diss., Bordeaux, 2024. http://www.theses.fr/2024BORD0407.

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Le vieillissement est associé à l’acquisition par les cellules souches hématopoïétiques (CSH) de mutations somatiques et d’altérations chromosomiques. Dans certains cas, l’acquisition d’une de ces anomalies confère à la CSH un avantage d’auto-renouvellement et de prolifération conduisant au développement d’une hématopoïèse clonale. Le terme d’hématopoïèse clonale de potentiel indéterminé (Clonal Hematopoiesis of indeterminate potential - CHIP) caractérise la détection dans le sang d’un clone portant une mutation somatique sur un gène associé aux leucémies avec une fréquence allélique ≥2 % mais
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Book chapters on the topic "Clonal hematopoiesis of indeterminate potential"

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Menendez-Gonzalez, Juan Bautista, and Neil P. Rodrigues. "Exploring the Associations Between Clonal Hematopoiesis of Indeterminate , , and." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-1924-7_5.

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Chertkov, J. L., E. I. Deryugina, N. J. Drize, and E. Yu Sadovnikova. "Limited Proliferative Potential of Primitive Hematopoietic Stem Cells: Hematopoiesis by Clonal Succession." In Haematology and Blood Transfusion / Hämatologie und Bluttransfusion. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74621-5_30.

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Xie, Zhuoer. "Clonal Hematopoiesis of Indeterminate Potential, Clonal Cytopenia of Undetermined Significance, and Precursor States of Myeloid Neoplasms." In Handbook of Hematologic Malignancies, 3rd ed. Springer Publishing Company, 2025. https://doi.org/10.1891/9780826184429.0014.

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Becerra Becerra, Edgardo, and Guadalupe García-Alcocer. "MicroRNAs and Their Role in Acute Lymphoblastic Leukemia." In Acute Leukemias [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.94960.

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Acute lymphoblastic leukemia (ALL) has been established as the most common acute leukemia in children, accounting for 80–85% of cases. ALL occurs mostly in children and it is considered as a high-risk disease in the elderlies. ALL is characterized by a clonal disorder where the normal hematopoiesis is replaced by a malignant clonal expansion of lymphoid progenitors. Although many therapeutic strategies have been established to treat ALL leading to improved survival rates, the short-term and long-term complications derived from treatment toxicity represent a critical risk for patients. The trea
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Conference papers on the topic "Clonal hematopoiesis of indeterminate potential"

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Mansouri, S., S. Kuhnert, M. Rieger, et al. "Association of Clonal Hematopoiesis of Indeterminate Potential With Inflammatory Gene Expression in Patients With COPD." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5736.

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Reed, Sarah C., Chad Potts, P. Brent Ferrell, and Ben Ho Park. "1492 Clonal hematopoiesis of indeterminate potential alters solid tumor microenvironment and outcomes in triple negative breast cancer." In SITC 38th Annual Meeting (SITC 2023) Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.1492.

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Bertamini, Luca, Claudia Sala, Nicola Martinelli, et al. "Abstract 1229: Clonal hematopoiesis of indeterminate potential (CHIP), centenarians and age-related cardiovascular risk: Is TET2 the culprit." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-1229.

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Severson, Eric A. A., Gregory M. Riedlinger, Mendel Goldfinger, et al. "Abstract LB-B02: Detection of Clonal Hematopoiesis of Indeterminate Potential in Solid Tumors: Implications for Interpretation of Molecular Testing." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; October 26-30, 2017; Philadelphia, PA. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1535-7163.targ-17-lb-b02.

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Mouhieddine, Tarek H., Jihye Park, Robert Redd, et al. "Abstract 2954: Immunomodulator maintenance post autologous stem cell transplant predicts better outcome in multiple myeloma patients with clonal hematopoiesis of indeterminate potential." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-2954.

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