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Journal articles on the topic 'Clonmel (Ireland)'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

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1

Minogue, Patrick J. "Housing at Clonmel, Ireland." Batiment International, Building Research and Practice 15, no. 1-6 (1987): 210–14. http://dx.doi.org/10.1080/09613218708726818.

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2

McGrath, Bríd. "Reconstructing an Early Modern Irish Economic Community." Irish Economic and Social History 44, no. 1 (2017): 122–42. http://dx.doi.org/10.1177/0332489317738608.

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Tax assessments provide unique information about the individual and relative wealth of early modern individuals and communities, but few such sources exist for early modern Ireland, so the survival of a tax assessment for the most prosperous inhabitants of Clonmel in 1642 is a unique source for the study of the town’s economic community in that year. An analysis of the tax paid by these men and women provides not merely unrivalled information about their personal wealth but also about the relative prosperity of different occupation groups, including merchants, craftsmen and women, the most imp

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3

Reidy, Conor. "Institutional power and the Irish borstal boy, 1906–21." Irish Historical Studies 38, no. 149 (2012): 36–51. http://dx.doi.org/10.1017/s0021121400000614.

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This article will examine the unique power structure that governed the lives of inmates of Ireland's borstal institution from its foundation in 1906 until the end of British rule in 1921. The borstal system was developed at the close of the nineteenth century at a time when penal administrators were searching for new and more enlightened modes of detention. Reform became something of a catchphrase and the borstal was one of two approaches, the other being the inebriate reformatory system that captured the imagination of Home Office officials. During this time there was a transition of leadersh

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4

Connolly, Philomena. "XLIV: An attempted escape from Dublin castle: the trial of William and Walter de Bermingham, 1332." Irish Historical Studies 29, no. 113 (1994): 100–104. http://dx.doi.org/10.1017/s0021121400018794.

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On 11 July 1332 William de Bermingham, brother of the earl of Louth, was hanged at Dublin by order of the justiciar, Anthony de Lucy. This event is recorded by Clyn, by the author of the Annals of Ross and by the Dublin annalist, all of whom praise Bermingham for his military excellence but do not give any explanation for the execution. All the chroniclers mention Bermingham’s arrest earlier in the year, but the connexion between the two events is never stated.In February and March 1332 William had been indicted by juries at Clonmel and Limerick of involvement in two alleged conspiracies, one

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5

Dwan, Bill. "Using GIS to Explore the Retail Structure of Market Towns in Ireland." International Journal of Applied Geospatial Research 4, no. 1 (2013): 17–31. http://dx.doi.org/10.4018/jagr.2013010102.

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The paper presents a Geographic Information System (GIS)-based approach to quantifying and comparing retail structures. It explores the retail landscape of the three largest market towns in County Tipperary, Republic of Ireland, namely: Clonmel, Thurles and Nenagh. The context for the study is provided through an overview of recent changes in the Irish retail sector, the dynamic of market towns and the associated challenges inherent in defining retail structure. Using demographic and retail store location data a demand threshold analysis is undertaken on custom-defined catchments for each mark

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6

Gillespie, Raymond. "The Presbyterian Revolution in Ulster, 1660-1690." Studies in Church History 25 (1989): 159–70. http://dx.doi.org/10.1017/s0424208400008652.

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In early 1642 a Scottish army under the command of Robert Munroe arrived in Ulster as part of a scheme to defeat the native Irish rebellion which had begun late in the previous year. The conquest was not to be purely a military one. As a contemporary historian of Presbyterianism, Patrick Adair, observed ‘it is certain God made that army instrumental for bringing church governments, according to His own institutions, to Ireland … and for spreading the covenants’. The form of church government was that of the Presbyterian Church of Scotland, and in June 1642 the chaplains and officers establishe

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FITZGERALD, J. R., W. J. MEANEY, P. J. HARTIGAN, C. J. SMYTH, and V. KAPUR. "Fine-structure molecular epidemiological analysis of Staphylococcus aureus recovered from cows." Epidemiology and Infection 119, no. 2 (1997): 261–69. http://dx.doi.org/10.1017/s0950268897007802.

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Sixty-three Staphylococcus aureus isolates recovered from bovine sources in the USA and the Republic of Ireland were characterized by multilocus enzyme electrophoresis (MLEE), ribotyping, and random amplified polymorphic DNA polymerase chain reaction (RAPD–PCR) typing at two separate laboratories. The S. aureus isolates were assigned by MLEE to 10 electrophoretic types (ETs) (Index of Discrimination, D=0·779). In contrast, the same isolates were assigned to 13 ribotypes (D=0·888), and to 12 RAPD types (D=0·898). A common clone, ET3, of worldwide distribution, was represented by six distinct co

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8

Kinnevey, Peter M., Anna C. Shore, Grainne I. Brennan, et al. "Extensive Genetic Diversity Identified among Sporadic Methicillin-Resistant Staphylococcus aureus Isolates Recovered in Irish Hospitals between 2000 and 2012." Antimicrobial Agents and Chemotherapy 58, no. 4 (2014): 1907–17. http://dx.doi.org/10.1128/aac.02653-13.

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ABSTRACTClonal replacement of predominant nosocomial methicillin-resistantStaphylococcus aureus(MRSA) strains has occurred several times in Ireland during the last 4 decades. However, little is known about sporadically occurring MRSA in Irish hospitals or in other countries. Eighty-eight representativepvl-negative sporadic MRSA isolates recovered in Irish hospitals between 2000 and 2012 were investigated. These yielded unusual pulsed-field gel electrophoresis and antibiogram-resistogram typing patterns distinct from those of the predominant nosocomial MRSA clone, ST22-MRSA-IV, during the study

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9

ABBOTT, Y., F. C. LEONARD, and B. K. MARKEY. "Detection of three distinct genetic lineages in methicillin-resistantStaphylococcus aureus(MRSA) isolates from animals and veterinary personnel." Epidemiology and Infection 138, no. 5 (2010): 764–71. http://dx.doi.org/10.1017/s0950268809991580.

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SUMMARYThis study involved the phenotypic and molecular characterization of a population of methicillin-resistantStaphylococcus aureusisolates from animals and from veterinary personnel in Ireland. Isolates from 77 animals (dogs,n=44; cats,n=4; horses,n=29) and from 28 veterinary personnel were characterized using their antimicrobial resistance profiles and pulsed-field gel electrophoresis patterns. In addition, a representative number of these isolates (n=52) were further analysed usingspa-typing techniques. The results obtained identified the presence of three distinct clonal complexes, CC5,

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10

McMahon, Theo, Sean Slowey, and Maire O. Neill. "Inscriptions from St Tighernach's Church of Ireland Graveyard Clones." Clogher Record 13, no. 1 (1988): 90. http://dx.doi.org/10.2307/27699276.

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11

Bulas, Ryszarda M. "Wysokie krzyże iryjskie a grobowce Edessy." Vox Patrum 55 (July 15, 2010): 111–19. http://dx.doi.org/10.31743/vp.4328.

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The author in the article refers to a broad discussion on the origin of ideas and artistic inspiration for Celtic crosses. She refers to a Hilary Richardson of the Armenian and Georgian origin of the concept of the Celtic cross, also to the results of her book The symbols of pagan Celtic crosses. Myths, symbols, images. In this book she indicates a cultural affinity of Ireland and the Syria. She points to the compositional and iconographic parallels between the Early Medieval Irish crosses and tombs mosaics of Edessa, dated to the III century. Reinforcing the thesis of H. Richardson, indicates

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12

Pan, Haibin, Yuqian Yan, Jing Zhang, et al. "Rapid Construction of a Replication-Competent Infectious Clone of Human Adenovirus Type 14 by Gibson Assembly." Viruses 10, no. 10 (2018): 568. http://dx.doi.org/10.3390/v10100568.

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In 1955, Human adenovirus type 14 (HAdV-B14p) was firstly identified in a military trainee diagnosed as acute respiratory disease (ARD) in the Netherlands. Fifty years later, a genomic variant, HAdV-B14p1, re-emerged in the U.S. and caused large and fatal ARD outbreaks. Subsequently, more and more ARD outbreaks occurred in Canada, the UK, Ireland, and China, in both military and civil settings. To generate a tool for the efficient characterization of this new genomic variant, a full-length infectious genomic clone of HAdV-B14 was successfully constructed using one-step Gibson Assembly method i

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13

Reid, H. I., A. A. Griffen, and T. H. Birkbeck. "Isolates of Piscirickettsia salmonis from Scotland and Ireland Show Evidence of Clonal Diversity." Applied and Environmental Microbiology 70, no. 7 (2004): 4393–97. http://dx.doi.org/10.1128/aem.70.7.4393-4397.2004.

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ABSTRACT Salmonid rickettsial septicemia, caused by Piscirickettsia salmonis, causes major mortalities in Chilean salmonid aquaculture and is an increasing problem in Atlantic salmon in Ireland and Scotland. Analysis of 16S-to-23S internal transcribed sequences and 16S ribosomal DNA (rDNA) shows that Irish isolates of P. salmonis form two new groups of the organism while Scottish isolates cluster together with Norwegian and Canadian isolates from Atlantic salmon.

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Kilmartin, Donna, D. Morris, C. O'Hare, G. Corbett-Feeney, and M. Cormican. "Clonal Expansion May Account for High Levels of Quinolone Resistance in Salmonella enterica Serovar Enteritidis." Applied and Environmental Microbiology 71, no. 5 (2005): 2587–91. http://dx.doi.org/10.1128/aem.71.5.2587-2591.2005.

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ABSTRACT We have observed a high incidence of isolated nalidixic acid resistance in Salmonella enterica serovar Enteritidis isolates in Ireland, particularly isolates of phage type 1 (PT1). A group of nalidixic acid-resistant (n = 22) and nalidixic acid-susceptible (n = 28) isolates of serovar Enteritidis from multiple sites in Ireland were selected. Isolates were typed by pulsed-field gel electrophoresis (PFGE) with XbaI, and the MICs for nalidixic acid and ciprofloxacin were determined. Mutations associated with nalidixic acid resistance in clinical isolates and laboratory mutants of serovar

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15

Gross, R. J., B. Rowe, and E. J. Threlfall. "Escherichia coli 0142.H6; a drug-resistant enteropathogenic clone?" Journal of Hygiene 94, no. 2 (1985): 181–91. http://dx.doi.org/10.1017/s0022172400061386.

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SUMMARYFor many years strains of Escherichia coli belonging to particular serotypes (EPEC) were a common cause of outbreaks of infantile enteritis in Europe and North America. E. coli 0142. H6 was first isolated from infants with diarrhoea in Indonesia in 1960 and a further outbreak occurred in Mexico in 1965. Between 1967 and 1972 outbreaks of infantile enteritis caused by E. coli 0142 were reported in hospitals in Scotland, England, Northern Ireland and Eire. Sporadic cases occurred in Canada in 1972 and a further outbreak occurred in Arizona, U.S.A. in 1975. Strains from all these incidents

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16

MORRIS, D., M. O'CONNOR, R. IZDEBSKI, et al. "Dissemination of clonally related multidrug-resistantKlebsiella pneumoniaein Ireland." Epidemiology and Infection 144, no. 2 (2015): 443–48. http://dx.doi.org/10.1017/s0950268815001041.

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SUMMARYIn October 2012, an outbreak of gentamicin-resistant, ciprofloxacin non-susceptible extended-spectrumβ-lactamase (ESBL)-producingKlebsiella pneumoniaeoccurred in a neonatal intensive care unit in Ireland. In order to determine whether the outbreak strain was more widely dispersed in the country, 137 isolates ofK. pneumoniaewith this resistance phenotype collected from 17 hospitals throughout Ireland between January 2011 and July 2013 were examined. ESBL production was confirmed phenotypically and all isolates were screened for susceptibility to 19 antimicrobial agents and for the presen

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17

HAYES, K., L. COTTER, L. BARRY, and F. O'HALLORAN. "Emergence of the L phenotype in Group B Streptococci in the South of Ireland." Epidemiology and Infection 145, no. 16 (2017): 3535–42. http://dx.doi.org/10.1017/s0950268817002461.

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SUMMARYGroup B Streptococcal isolates (n= 235) from the South of Ireland were characterised by serotyping, antimicrobial susceptibility and determination of the phenotypic and genotypic mechanisms of resistance. Resistance to erythromycin and clindamycin was observed in 21·3% and 20·4% of the total population, respectively. The c-MLSB phenotype was the most common phenotype detected (62%), withermBbeing the predominant genetic determinant, present in 84% of resistant isolates. The rare L phenotype was observed in 2·9% (n= 7) of isolates, four of which harboured thelsaCgene responsible for clin

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18

Matsui, T., J. E. Moore, C. Patterson, B. C. Millar, and M. Matsuda. "Molecular characterisation of human campylobacteriosis in Northern Ireland: evidence of clonal stability." Irish Journal of Medical Science 171, no. 1 (2002): 33–36. http://dx.doi.org/10.1007/bf03168939.

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19

Shore, Anna C., Angela S. Rossney, Orla M. Brennan, et al. "Characterization of a Novel Arginine Catabolic Mobile Element (ACME) and Staphylococcal Chromosomal CassettemecComposite Island with Significant Homology to Staphylococcus epidermidis ACME Type II in Methicillin-Resistant Staphylococcus aureus Genotype ST22-MRSA-IV." Antimicrobial Agents and Chemotherapy 55, no. 5 (2011): 1896–905. http://dx.doi.org/10.1128/aac.01756-10.

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ABSTRACTThe arginine catabolic mobile element (ACME) is prevalent among methicillin-resistantStaphylococcus aureus(MRSA) isolates of sequence type 8 (ST8) and staphylococcal chromosomal cassettemec(SCCmec) type IVa (USA300) (ST8-MRSA-IVa isolates), and evidence suggests that ACME enhances the ability of ST8-MRSA-IVa to grow and survive on its host. ACME has been identified in a small number of isolates belonging to other MRSA clones but is widespread among coagulase-negative staphylococci (CoNS). This study reports the first description of ACME in two distinct strains of the pandemic ST22-MRSA

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20

ONG, G., I. WILSON, B. SMYTH, and P. ROONEY. "Antimicrobial resistance in non-typhoidal salmonellas from humans in Northern Ireland, 2001–2003: standardization needed for better epidemiological monitoring." Epidemiology and Infection 135, no. 4 (2006): 675–80. http://dx.doi.org/10.1017/s0950268806007291.

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SUMMARYThis study investigated the identification and antimicrobial susceptibility testing of Salmonella isolates in Northern Ireland during 2001–2003. All six participating hospital laboratories used similar methods. Identification and antimicrobial resistance of human enteric (n=897) Salmonella isolates were analysed by retrospective collation of laboratory records. Resistance of human Salmonella isolates to nalidixic acid was 16% but resistance to ciprofloxacin or cefotaxime was rare (<1%). Minor inter-laboratory variations in sensitivity testing practices make it difficult to compare an

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21

Owen,, Robert J., and Jacqueline Xerry. "Tracing clonality of Helicobacter pylori infecting family members from analysis of DNA sequences of three housekeeping genes (ureI, atpA and ahpC), deduced amino acid sequences, and pathogenicity-associated markers (cagA and vacA)." Journal of Medical Microbiology 52, no. 6 (2003): 515–24. http://dx.doi.org/10.1099/jmm.0.04988-0.

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Helicobacter pylori, a Gram-negative bacterium, is a causal agent of peptic ulcers and is estimated to infect the gastric mucosa of at least half of the world's population. As primary infections are acquired mainly by household contact, studies on family clusters provide a model for investigating transmission and the natural history of initial infection. Here, sequence typing exploiting genetic variation in core fragments of three key housekeeping loci (ureI, atpA and ahpC) was used to determine clonal descent amongst isolates of ten members of four families in Northern Ireland and a family wi

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22

Truccollo, Brendha, Paul Whyte, Catherine Burgess, and Declan Bolton. "Genetic characterisation of a subset of Campylobacter jejuni isolates from clinical and poultry sources in Ireland." PLOS ONE 16, no. 3 (2021): e0246843. http://dx.doi.org/10.1371/journal.pone.0246843.

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Campylobacter spp. is a significant and prevalent public health hazard globally. Campylobacter jejuni is the most frequently recovered species from human cases and poultry are considered the most important reservoir for its transmission to humans. In this study, 30 Campylobacter jejuni isolates were selected from clinical (n = 15) and broiler (n = 15) sources from a larger cohort, based on source, virulence, and antimicrobial resistance profiles. The objective of this study was to further characterise the genomes of these isolates including MLST types, population structure, pan-genome, as well

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McKay, Gareth J., Damian Egan, Elizabeth Morris, Carol Scott, and Averil E. Brown. "Genetic and Morphological Characterization ofCladobotryum Species Causing Cobweb Disease of Mushrooms." Applied and Environmental Microbiology 65, no. 2 (1999): 606–10. http://dx.doi.org/10.1128/aem.65.2.606-610.1999.

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ABSTRACT Cladobotryum dendroides (= Dactylium dendroides) has hitherto been regarded as the major causal agent of cobweb disease of the cultivated mushroom, Agaricus bisporus. Nucleotide sequence data for the internal transcribed spacer (ITS) regions of four Cladobotryum/Hypomyces species reported to be associated with cobweb disease, however, indicate that the most common pathogen is now C. mycophilum. This cobweb pathogen varies somewhat in conidial septation from published descriptions of C. mycophilum and lacks the distinctive colony odor. ITS sequencing revealed minor nucleotide variation

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Shore, A. C., S. C. Tecklenborg, G. I. Brennan, R. Ehricht, S. Monecke, and D. C. Coleman. "Panton-Valentine Leukocidin-Positive Staphylococcus aureus in Ireland from 2002 to 2011: 21 Clones, Frequent Importation of Clones, Temporal Shifts of Predominant Methicillin-Resistant S. aureus Clones, and Increasing Multiresistance." Journal of Clinical Microbiology 52, no. 3 (2013): 859–70. http://dx.doi.org/10.1128/jcm.02799-13.

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25

Humphries, S. E., M. E. Chaves, F. Tata, et al. "A study of the structure of the gene for lecithin: Cholesterol acyltransferase in four unrelated individuals with familial lecithin: Cholesterol acyltransferase deficiency." Clinical Science 74, no. 1 (1988): 91–96. http://dx.doi.org/10.1042/cs0740091.

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1. We have used polyclonal antibodies and a complementary DNA clone for human lecithinxholesterol acyltransferase (LCAT) to study LCAT protein and the structure of the LCAT gene, respectively, in patients with familial LCAT deficiency from Norway, Ireland, Germany and Italy. 2. The patients had low levels of non-functional LCAT protein in their serum as measured by rocket Immunoelectrophoresis; its mol. wt. of approximately 68 000 was identical with that of LCAT in normal plasma, as judged by immunoblotting. 3. Enzymatic digestion of DNA samples from the patients produced LCAT gene fragments w

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26

Brown, Daniel. "Select document: a charter of Hugh II de Lacy, earl of Ulster, to Hugh Hose (2 March 1207)." Irish Historical Studies 38, no. 151 (2013): 492–510. http://dx.doi.org/10.1017/s0021121400001619.

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In 1206, the year after he was created earl of Ulster by King John, the forces of Hugh II de Lacy (d. 1242) devastated the ecclesiastical civitas of Armagh for ten successive days and nights. Then, turning southwest into Monaghan, de Lacy laid waste ‘Teach Damhnata’ (Tydavnet), ‘Ceall Muragáin’ (Kilmore), and Clones, before striking northwards into Tír Eógain. There, he attacked Tullaghoge, seat of the king of Cenél nEógain, Áed Méith Ua Néill (d. 1230), reaching as far north as Ciannachta (bar. Keenaght, County Londonderry). This campaign, undertaken with the ‘Foreigners of Meath and of Leins

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27

Schmidt, M., I. B. Bøgh, Y. Du, et al. "85 PREGNANCIES AND VIABILITY OF THE OFFSPRING AFTER TRANSFER OF HANDMADE CLONED PORCINE EMBRYOS." Reproduction, Fertility and Development 19, no. 1 (2007): 160. http://dx.doi.org/10.1071/rdv19n1ab85.

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In several species, nuclear transfer causes a high frequency of fetal loss, high birth weight, malformations, and neonatal death. This study investigates the fetal development of porcine embryos produced by handmade cloning (HMC) and compares the piglets with littermates produced by traditional cloning (TC). HMC embryos were produced from one fetal cell line, LYxD (Landrace/Yorkshire x Duroc) and TC from another (LYDxLYD). For transfer, 11 sows were weaned, and at cycle stage Day 4 after heat, they were anesthetized in lateral recumbence. Through an abdominal incision 40–60 Days 5–7 embryos (6

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Whatmore, Adrian M., Samantha J. King, Neil C. Doherty, Daniel Sturgeon, Neil Chanter, and Christopher G. Dowson. "Molecular Characterization of Equine Isolates ofStreptococcus pneumoniae: Natural Disruption of Genes Encoding the Virulence Factors Pneumolysin and Autolysin." Infection and Immunity 67, no. 6 (1999): 2776–82. http://dx.doi.org/10.1128/iai.67.6.2776-2782.1999.

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ABSTRACT Although often considered a strict human pathogen,Streptococcus pneumoniae has been reported to infect and cause pneumonia in horses, although the pathology appears restricted compared to that of human infections. Here we report on the molecular characterization of a group of S. pneumoniae isolates obtained from horses in England and Ireland. Despite being obtained from geographically distinct locations, the isolates were found to represent a tight clonal group, virtually identical to each other but genetically distinguishable from more than 120 divergent isolates of human S. pneumoni

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29

Khera, Akhil, Katja Kimberger, Fotios Panitsas, et al. "Long Term Outcomes in Monoclonal Gammopathy of Renal Significance (MGRS)." Blood 128, no. 22 (2016): 5948. http://dx.doi.org/10.1182/blood.v128.22.5948.5948.

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Abstract Background: MGRS is a heterogeneous group of pathologic renal conditions attributed to a clonal plasma cell disorder, without classical features of myeloma. However, there is a need to distinguish MGRS from MGUS and unrelated renal abnormality as the clonal protein in MGRS plays a direct role in kidney damage and requires treatment of the underlying clone. Outcomes in patients with diagnosis of cast nephropathy and renal amyloidosis have been previously reported. But long-term outcomes of MGRS patients with other renal histologies remain unclear. Also data on whether the level of tumo

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SMYTH, DAVIDA S., JEAN KENNEDY, JANE TWOHIG, HELEN MIAJLOVIĆ, DECLAN BOLTON, and CYRIL J. SMYTH. "Staphylococcus aureus Isolates from Irish Domestic Refrigerators Possess Novel Enterotoxin and Enterotoxin-like Genes and Are Clonal in Nature." Journal of Food Protection 69, no. 3 (2006): 508–15. http://dx.doi.org/10.4315/0362-028x-69.3.508.

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A previous study carried out by the National Food Centre in Dublin on bacterial contamination of Irish domestic refrigeration systems revealed that 41% were contaminated with Staphylococcus aureus. One hundred fifty-seven S. aureus isolates were screened by multiplex PCR analysis for the presence of 15 staphylococcal enterotoxin and enterotoxin-like genes (seasee, seg-sei, selj-selo, and selq) and the toxic shock toxin superantigen tst gene. Of the refrigerator isolates, 64.3% possessed more than one staphylococcal enterotoxin or staphylococcal enterotoxin–like gene. All bar one of the 101 sta

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Morris, Dearbhaile, Martina Ni Chulain, and Martin Cormican. "Dissemination of clonal groups of uropathogenic Escherichia coli is not a significant contributor to trimethoprim and sulfamethoxazole resistance in Galway, Ireland." International Journal of Antimicrobial Agents 30, no. 1 (2007): 97–98. http://dx.doi.org/10.1016/j.ijantimicag.2007.02.016.

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Lynch, Caoimhe T., Helen Lynch, Sarah Burke, et al. "Antimicrobial Resistance Determinants Circulating among Thermophilic Campylobacter Isolates Recovered from Broilers in Ireland Over a One-Year Period." Antibiotics 9, no. 6 (2020): 308. http://dx.doi.org/10.3390/antibiotics9060308.

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Campylobacteriosis is the leading cause of human bacterial gastroenteritis, very often associated with poultry consumption. Thermophilic Campylobacter (Campylobacter jejuni and Campylobacter coli) isolates (n = 158) recovered from broiler neck skin and caecal contents in Ireland over a one-year period, resistant to at least one of three clinically relevant antimicrobial classes, were screened for resistance determinants. All ciprofloxacin-resistant isolates (n = 99) harboured the C257T nucleotide mutation (conferring the Thr-86-Ile substitution) in conjunction with other synonymous and nonsyno

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Shore, Anna, Angela S. Rossney, Conor T. Keane, Mark C. Enright, and David C. Coleman. "Seven Novel Variants of the Staphylococcal Chromosomal Cassette mec in Methicillin-Resistant Staphylococcus aureus Isolates from Ireland." Antimicrobial Agents and Chemotherapy 49, no. 5 (2005): 2070–83. http://dx.doi.org/10.1128/aac.49.5.2070-2083.2005.

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ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) isolates recovered in Irish hospitals between 1971 and 2002 were characterized using multilocus sequence typing (MLST) (n = 130) and SCCmec typing (n = 172). Where atypical SCCmec typing results were obtained, PCR amplification of entire SCCmec elements, analysis of amplimer mobility, and nucleotide sequencing were undertaken. MLST revealed that 129/130 isolates had the same genotypes as internationally spread MRSA clones, including ST239, ST247, ST250, ST5, ST22, ST36, and ST8. A novel genotype, ST496, was identified in one isolate.

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Earls, Megan R., Anna C. Shore, Gráinne I. Brennan, et al. "A novel multidrug-resistant PVL-negative CC1-MRSA-IV clone emerging in Ireland and Germany likely originated in South-Eastern Europe." Infection, Genetics and Evolution 69 (April 2019): 117–26. http://dx.doi.org/10.1016/j.meegid.2019.01.021.

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35

Steinum, Terje M., Süheyla Karataş, Nora Tandstad Martinussen, Pedro M. Meirelles, Fabiano L. Thompson, and Duncan J. Colquhoun. "Multilocus Sequence Analysis of Close Relatives Vibrio anguillarum and Vibrio ordalii." Applied and Environmental Microbiology 82, no. 18 (2016): 5496–504. http://dx.doi.org/10.1128/aem.00620-16.

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ABSTRACTThe genetic heterogeneity of the close relativesVibrio anguillarumandVibrio ordalii, both serious pathogens of fish causing extensive losses in aquaculture, was studied. Eight housekeeping genes, i.e.,atpA,ftsZ,gapA,gyrB,mreB,rpoA,topA, andpyrH, were partially sequenced in 116 isolates from diverse fish species and geographical areas. The eight genes appear to be under purifying selection, and the genetic diversity in the total data set was estimated to be 0.767 ± 0.026. Our multilocus sequence analysis (MLSA) scheme identified several widespread clonal complexes and resolved the isola

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Touzet, Nicolas, Jose M. Franco, and Robin Raine. "Characterization of Nontoxic and Toxin-Producing Strains of Alexandrium minutum (Dinophyceae) in Irish Coastal Waters." Applied and Environmental Microbiology 73, no. 10 (2007): 3333–42. http://dx.doi.org/10.1128/aem.02161-06.

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ABSTRACT A comparative analysis of the morphology, toxin composition, and ribosomal DNA (rDNA) sequences was performed on a suite of clonal cultures of the potentially toxic dinoflagellate Alexandrium minutum Halim. These were established from resting cysts or vegetative cells isolated from sediment and water samples taken from the south and west coasts of Ireland. Results revealed that strains were indistinguishable, both morphologically and through the sequencing of the D1-D2 domain of the large subunit and the ITS1-5.8S-ITS2 regions of the rDNA. High-performance liquid chromatography fluore

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Mueller, Ulrich G., Alexander S. Mikheyev, Scott E. Solomon, and Michael Cooper. "Frontier mutualism: coevolutionary patterns at the northern range limit of the leaf-cutter ant–fungus symbiosis." Proceedings of the Royal Society B: Biological Sciences 278, no. 1721 (2011): 3050–59. http://dx.doi.org/10.1098/rspb.2011.0125.

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Tropical leaf-cutter ants cultivate the fungus Attamyces bromatificus in a many-to-one, diffuse coevolutionary relationship where ant and fungal partners re-associate frequently over time. To evaluate whether ant– Attamyces coevolution is more specific (tighter) in peripheral populations, we characterized the host-specificities of Attamyces genotypes at their northern, subtropical range limits (southern USA, Mexico and Cuba). Population-genetic patterns of northern Attamyces reveal features that have so far not been observed in the diffusely coevolving, tropical ant– Attamyces associations. Th

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Quinlivan, Michelle, Frank Cook, Rachel Kenna, John J. Callinan, and Ann Cullinane. "Genetic characterization by composite sequence analysis of a new pathogenic field strain of equine infectious anemia virus from the 2006 outbreak in Ireland." Journal of General Virology 94, no. 3 (2013): 612–22. http://dx.doi.org/10.1099/vir.0.047191-0.

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Equine infectious anemia virus (EIAV), the causative agent of equine infectious anaemia (EIA), possesses the least-complex genomic organization of any known extant lentivirus. Despite this relative genetic simplicity, all of the complete genomic sequences published to date are derived from just two viruses, namely the North American EIAVWYOMING (EIAVWY) and Chinese EIAVLIAONING (EIAVLIA) strains. In 2006, an outbreak of EIA occurred in Ireland, apparently as a result of the importation of contaminated horse plasma from Italy and subsequent iatrogenic transmission to foals. This EIA outbreak wa

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McManus, D. P., and A. K. Rishi. "Genetic heterogeneity withinEchinococcus granulosus: isolates from different hosts and geographical areas characterized with DNA probes." Parasitology 99, no. 1 (1989): 17–29. http://dx.doi.org/10.1017/s0031182000060984.

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SUMMARYA segment of the ribosomal RNA gene ofSchistosoma mansoniand a DNA fragment specific toEchinococcus granulosus, cloned in plasmids, have been used as DNA probes to assess the extent of genetic variability withinE. granulosusand some distinct strains have been identified. The DNA analysis, involving restriction endonuclease digestion and Southern blot hybridization with the probes, did not demonstrate any significant genetic variation within the U.K. horse/dog or sheep/dog strains but confirmed the distinctiveness of the two strains shown in previous studies. The sheep/dog strain was sho

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Brennan, Gráinne I., Yvonne Abbott, Aisling Burns, et al. "The Emergence and Spread of Multiple Livestock-Associated Clonal Complex 398 Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Strains among Animals and Humans in the Republic of Ireland, 2010–2014." PLOS ONE 11, no. 2 (2016): e0149396. http://dx.doi.org/10.1371/journal.pone.0149396.

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Sévellec, Yann, Arnaud Felten, Nicolas Radomski, et al. "Genetic Diversity of Salmonella Derby from the Poultry Sector in Europe." Pathogens 8, no. 2 (2019): 46. http://dx.doi.org/10.3390/pathogens8020046.

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Salmonella Derby (S. Derby) is emerging in Europe as a predominant serovar in fattening turkey flocks. This serovar was recorded as being predominant in the turkey sector in 2014 in the United Kingdom (UK). Only two years later, in 2016, it was also recorded in the turkey and broiler sectors in Ireland and Spain. These S. Derby isolates were characterised as members of the multilocus sequence type (MLST) profile 71 (ST71). For the first time, we characterise by whole genome sequencing (WGS) analysis a panel of 90 S. Derby ST71 genomes to understand the routes of transmission of this emerging p

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Remington, S. G. "Chicken filensin: a lens fiber cell protein that exhibits sequence similarity to intermediate filament proteins." Journal of Cell Science 105, no. 4 (1993): 1057–68. http://dx.doi.org/10.1242/jcs.105.4.1057.

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Filensin, a 100 kDa, membrane-associated, cytoskeletal protein, is uniquely expressed in the lens fiber cell (Merdes, A., Brunkener, M., Horstmann, H., and Georgatos, S. D. (1991) J. Cell Biol. 115, 397–410). I cloned and sequenced a full-length chicken lens cDNA encoding filensin, also known as CP95 (Ireland, M. and Maisel, H. (1989) Lens and Eye Toxicity Research 6, 623–638). The deduced amino acid sequence of 657 residues contained an internal 280 residue heptad repeat domain with sequence similarities to the rod domain of intermediate filament proteins. The putative filensin rod domain cou

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Crowley, Maeve P., Barry M. Kevane, Joesph A. Eustace, Susan O'Shea, and Oonagh M. Gilligan. "Thromboprophylaxis In Myeloma: A National Survey." Blood 122, no. 21 (2013): 1694. http://dx.doi.org/10.1182/blood.v122.21.1694.1694.

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Abstract Background Venous thromboembolism (VTE) is a common occurrence in cancer patients. It is a leading cause of death, coming second only to cancer progression (Khorana et al 2007). The risk is further increased by admission to hospital, surgery and administration of chemotherapy (Heit et al 2000, Kröger et al 2006). Thrombotic complications can delay or interfere with cancer therapy, prolong hospitalization and lead to increased use of resources (Carrier et al 2009). Myeloma, a malignant disorder characterised by the clonal proliferation of plasma cells, has long been linked to VTE (Cato

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Corcoran, D., T. Fair, D. Rizos, et al. "216 IDENTIFICATION OF DIFFERENTIALLY EXPRESSED GENES IN BOVINE EMBRYOS CULTURED IN VIVO OR IN VITRO." Reproduction, Fertility and Development 17, no. 2 (2005): 259. http://dx.doi.org/10.1071/rdv17n2ab216.

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The post-fertilization culture environment of the bovine embryo is known to influence the quality of the resulting blastocyst, manifested in terms of morphology, cryotolerance, and the relative gene transcript abundance of several candidate genes. This may have consequences for the pregnancy rate following embryo transfer. The objective of the current study was to take a broader approach toward identifying differentially expressed genes in bovine blastocysts derived from either in vivo or in vitro culture. Presumptive zygotes, produced by in vitro maturation and fertilization, were randomly as

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Myers, Kasiani, Jie He, Ben Goldberg, et al. "Incidence of Myeloid Malignancy in Shwachman-Diamond Syndrome: An International Cohort Study." Blood 144, Supplement 1 (2024): 2703. https://doi.org/10.1182/blood-2024-206661.

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Introduction: Shwachman Diamond syndrome (SDS) is a genetic bone marrow failure syndrome associated with a predisposition to developing myeloid malignancies. Survival is exceptionally poor for patients who develop MDS or AML. Due to the rarity of this condition, the cumulative risk of myeloid malignancies with age is not well characterized, and this understanding is critical to guide effective clinical interventions that improve survival. The paucity of data regarding malignancy risk poses a major barrier to transplant decisions for patients with this leukemia predisposition syndrome. To addre

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De Lavallade, Hugues, Sophie Jackson, Heather Oakervee, et al. "Interim Analysis of a Prospective Multicentre Study Using Next Generation Sequencing for Kinase Domain Mutational Analysis in CML Patients on First or Subsequent TKI Therapy." Blood 134, Supplement_1 (2019): 2935. http://dx.doi.org/10.1182/blood-2019-129825.

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Introduction Kinase domain mutations in the BCR-ABL1 gene are associated with resistance to tyrosine kinase inhibitors (TKI) in chronic myeloid leukaemia (CML). Next-generation Sequencing (NGS) allows detection of low-level kinase domain mutations as well as quantification of Variant Allele Frequency (VAF).We have previously demonstrated that NGS consistently detects early appearance of kinase domain (KD) mutations in CML patients (Kizilors et al. Lancet Haematology 2019)and highlighted the need for regular monitoring for KD mutations.To that end a multicentre prospective non-interventional st

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Mac Con Iomaire, Máirtín. "Coffee Culture in Dublin: A Brief History." M/C Journal 15, no. 2 (2012). http://dx.doi.org/10.5204/mcj.456.

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IntroductionIn the year 2000, a group of likeminded individuals got together and convened the first annual World Barista Championship in Monte Carlo. With twelve competitors from around the globe, each competitor was judged by seven judges: one head judge who oversaw the process, two technical judges who assessed technical skills, and four sensory judges who evaluated the taste and appearance of the espresso drinks. Competitors had fifteen minutes to serve four espresso coffees, four cappuccino coffees, and four “signature” drinks that they had devised using one shot of espresso and other ingr

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Horie, Masafumi, Yoshiyuki Akiyama, Hiroto Katoh, et al. "APRIL/BAFF upregulation is associated with clonal B‐cell expansion in Hunner‐type interstitial cystitis." Journal of Pathology, October 3, 2024. http://dx.doi.org/10.1002/path.6353.

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AbstractHunner‐type interstitial cystitis (HIC) is a chronic inflammatory disease of the urinary bladder with an unknown etiology. We conducted comprehensive immunogenomic profiling of bladder specimens obtained by biopsy and cystectomy from 37 patients with HIC. Next‐generation RNA sequencing demonstrated abundant plasma cell infiltration with frequent light chain restriction in HIC‐affected bladder tissue. Subsequent analysis of the B‐cell receptor repertoire revealed spatial and temporal expansion of B‐cell clones. The extent of B‐cell clonal expansion was significantly correlated with the

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Maguire, Mark, Niall DeLappe, Christina Clarke, et al. "Genomic and phylogenetic analysis of hypervirulent Klebsiella pneumoniae ST23 in Ireland." Microbial Genomics 11, no. 3 (2025). https://doi.org/10.1099/mgen.0.001373.

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Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a pathogen of global concern associated with invasive community-acquired infections. The combination of hypervirulence and carbapenem resistance can result in severe and difficult-to-treat infections. This retrospective study aimed to investigate the spread of hvKp sequence type 23 (ST23) in Ireland and the convergence of hypervirulent (hv) and antimicrobial resistance genotypes. Short-read sequences (PE300) for 90 K. pneumoniae ST23 isolates were generated by the Galway Reference Laboratory Services (GRLS). Isolates were from screening

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Drudy, D., N. Harnedy, S. Fanning, R. O'Mahony, and L. Kyne. "Increased antimicrobial resistance in clonal clostridium difficile isolates in Dublin Ireland." Endoscopy 37, no. 12 (2006). http://dx.doi.org/10.1055/s-2005-922882.

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