Academic literature on the topic 'Closed microfluidic system'

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Journal articles on the topic "Closed microfluidic system"

1

Debski, Pawel, Karolina Sklodowska, Jacek Michalski, Piotr Korczyk, Miroslaw Dolata, and Slawomir Jakiela. "Continuous Recirculation of Microdroplets in a Closed Loop Tailored for Screening of Bacteria Cultures." Micromachines 9, no. 9 (2018): 469. http://dx.doi.org/10.3390/mi9090469.

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Emerging microfluidic technology has introduced new precision controls over reaction conditions. Owing to the small amount of reagents, microfluidics significantly lowers the cost of carrying a single reaction. Moreover, in two-phase systems, each part of a dispersed fluid can be treated as an independent chemical reactor with a volume from femtoliters to microliters, increasing the throughput. In this work, we propose a microfluidic device that provides continuous recirculation of droplets in a closed loop, maintaining low consumption of oil phase, no cross-contamination, stabilized temperatu
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Steege, Tobias, Mathias Busek, Stefan Grünzner, Andrés Fabían Lasagni, and Frank Sonntag. "Closed-loop control system for well-defined oxygen supply in micro-physiological systems." Current Directions in Biomedical Engineering 3, no. 2 (2017): 363–66. http://dx.doi.org/10.1515/cdbme-2017-0075.

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AbstractTo improve cell vitality, sufficient oxygen supply is an important factor. A deficiency in oxygen is called Hypoxia and can influence for example tumor growth or inflammatory processes. Hypoxia assays are usually performed with the help of animal or static human cell culture models. The main disadvantage of these methods is that the results are hardly transferable to the human physiology. Microfluidic 3D cell cultivation systems for perfused hypoxia assays may overcome this issue since they can mimic the in-vivo situation in the human body much better. Such a Hypoxia-on-a-Chip system w
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Wang, Ningquan, Ruxiu Liu, Norh Asmare, Chia-Heng Chu, Ozgun Civelekoglu, and A. Fatih Sarioglu. "Closed-loop feedback control of microfluidic cell manipulation via deep-learning integrated sensor networks." Lab on a Chip 21, no. 10 (2021): 1916–28. http://dx.doi.org/10.1039/d1lc00076d.

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Loutherback, K., P. A. Bulur, and A. Dietz. "Process Development and Manufacturing: CLOSED MICROFLUIDIC SYSTEM FOR MANUFACTURING DENDRITIC CELL THERAPIES." Cytotherapy 24, no. 5 (2022): S171—S172. http://dx.doi.org/10.1016/s1465-3249(22)00448-0.

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Loutherback, K., P. A. Bulur, and A. Dietz. "Process Development and Manufacturing: CLOSED MICROFLUIDIC SYSTEM FOR MANUFACTURING DENDRITIC CELL THERAPIES." Cytotherapy 24, no. 5 (2022): S171—S172. http://dx.doi.org/10.1016/s1465-3249(22)00448-0.

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Fu, Hai, Wen Zeng, Songjing Li, and Shuai Yuan. "Electrical-detection droplet microfluidic closed-loop control system for precise droplet production." Sensors and Actuators A: Physical 267 (November 2017): 142–49. http://dx.doi.org/10.1016/j.sna.2017.09.043.

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Hansen, J. S., J. T. Ottesen, and A. Lemarchand. "Molecular dynamics simulations of valveless pumping in a closed microfluidic tube-system." Molecular Simulation 31, no. 14-15 (2005): 963–69. http://dx.doi.org/10.1080/08927020500419297.

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Yafia, Mohamed, Amir M. Foudeh, Maryam Tabrizian, and Homayoun Najjaran. "Low-Cost Graphene-Based Digital Microfluidic System." Micromachines 11, no. 9 (2020): 880. http://dx.doi.org/10.3390/mi11090880.

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In this work, the laser-scribing technique was used as a low-cost, rapid and facile method for fabricating digital microfluidic (DMF) systems. Laser-scribed graphene (LSG) electrodes are directly synthesized on flexible substrates to pattern the DMF electrode arrays. This facilitates the DMF electrodes’ fabrication process by eliminating many microfabrication steps. An electrowetting test was performed to investigate the effectiveness of the LSG DMF electrodes in changing the contact angles of droplets. Different DMF operations were successfully performed using the proposed LSG DMF chips in bo
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Lim, Hyunjung, Jae Young Kim, Seunghee Choo, et al. "Separation and Washing of Candida Cells from White Blood Cells Using Viscoelastic Microfluidics." Micromachines 14, no. 4 (2023): 712. http://dx.doi.org/10.3390/mi14040712.

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An early and accurate diagnosis of Candida albicans is critical for the rapid antifungal treatment of candidemia, a mortal bloodstream infection. This study demonstrates viscoelastic microfluidic techniques for continuous separation, concentration, and subsequent washing of Candida cells in the blood. The total sample preparation system contains two-step microfluidic devices: a closed-loop separation and concentration device and a co-flow cell-washing device. To determine the flow conditions of the closed-loop device, such as the flow rate factor, a mixture of 4 and 13 μm particles was used. C
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Jang, Kihoon, Yan Xu, Yo Tanaka, et al. "Single-cell attachment and culture method using a photochemical reaction in a closed microfluidic system." Biomicrofluidics 4, no. 3 (2010): 032208. http://dx.doi.org/10.1063/1.3494287.

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