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Journal articles on the topic 'Clumsiness in literature'

Author: Grafiati

Published: 26 July 2024

Last updated: 31 July 2025

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1

Ivry, Richard B. "Cerebellar Involvement in Clumsiness and Other Developmental Disorders." Neural Plasticity 10, no. 1-2 (2003): 141–53. http://dx.doi.org/10.1155/np.2003.141.

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Cerebellar abnormalities have been linked to a number of developmental disorders. Much evidence is based on the analysis of highresolution MRI scans. Imaging and behavioral studies have led researchers to consider functional contributions of the cerebellum beyond that associated with motor control. I review this literature, providing an analysis of different ways to consider the relation between cerebellar abnormalities and developmental disorders. Interestingly, although clumsiness is a problem of coordination, the contribution of cerebellar dysfunction to this developmental problem has recei

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Sannareddy, Rajesh, Rahul Lath, Michelle de Padua, and Alok Ranjan. "Meningioma with Intra- and Peritumoral Abscess." Indian Journal of Neurosurgery 07, no. 03 (2017): 220–22. http://dx.doi.org/10.1055/s-0037-1606820.

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AbstractThe association of meningioma with intra- and peritumoral brain abscess is rare. All cases reported in literature had some focus of infection in the body. We report a 56-year-old man with well-controlled diabetes mellitus found to have a space-occupying lesion upon evaluation for headache, vomiting, and clumsiness of right upper limb. Perioperatively, pus was found intra- and perilesionally around a thick, capsulated, dural-based, vascular lesion. Histopathology was suggestive of meningioma, and Escherichia coli was isolated upon culture.

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Reddy, Lankapothu Prem Balaji, Jagadeeshwar Kakumani, B. Srinidhi, and M. Sathish Kumar. "Sensory ganglionopathy and pituitary lesion in systemic lupus erythematosus: A case report and literature review." Romanian Journal of Rheumatology 34, no. 2 (2025): 85–90. https://doi.org/10.37897/rjr.2025.2.2.

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Background. Systemic lupus erythematosus (SLE) rarely manifests as sensory ganglionopathy or pituitary lesions, posing diagnostic challenges due to their atypical presentations and potential for irreversible damage. Case presentation. A 26-year-old male presented with five months of gait instability, numbness, and hand clumsiness, along with dry eyes and loose stools. Examination revealed sensory ataxia, absent reflexes, and positive anti-dsDNA antibodies, confirming SLE. Nerve conduction studies showed absent sensory nerve action potentials, consistent with sensory ganglionopathy. MRI identif

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Kresojevic, Nikola, Igor Petrovic, Natasa DragasevicMiskovic, and Vladimir Kostic. "Superficial siderosis: Case report and literature review." Srpski arhiv za celokupno lekarstvo 141, no. 3-4 (2013): 219–22. http://dx.doi.org/10.2298/sarh1304219k.

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Introduction. Superficial siderosis (SS) is caused by chronic subarachnoid bleeding and is characterized by free iron and hemosiderin deposition along the pial and subpial structures of central nervous system. SS leads to progressive and irreversible CNS damage. The most common causes of chronic subarachnoidal bleeding are tumors, head and spinal cord trauma, arteriovenous malformations and aneurysms. SS is characterized by clinical triad: sensorineural hearing loss, cerebellar ataxia and piramydal signs. Brain MR imaging is the investigation of choice for the diagnosis of SS. Typical findings

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Elvebakk, Kristine, Ingrid Elisabeth Johnsen, Cecilie Bendiksen Wold, Thomas Finsen, Harald Russwurm, and Vilhjalmur Finsen. "Simple Trapeziectomy for Arthrosis of the Basal Joint of the Thumb: 49 Thumbs Reviewed After Two Years." Hand Surgery 20, no. 03 (2015): 435–39. http://dx.doi.org/10.1142/s0218810415500367.

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Background: Many different surgical strategies for arthrosis of the carpometacarpal joint of the thumb are described in the literature. In 2010 we changed our routine procedure from an interposition arthroplasty using the abductor pollicis longus (APL) tendon to simple trapeziectomy without suspension or interposition. The purpose of this study was to review the clinical outcome after trapeziectomy and to compare it to those we had achieved with the APL procedure. Methods: We examined 49 hands operated with simple trapeziectomy during 2011-2012. Time between operation and review was 26 (15-26)

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Zaver, Dhillon B., and Nathan T. Douthit. "A Novel Mutation in the Adult-Onset Alexander’s Disease GFAP Gene." Case Reports in Medicine 2019 (January 10, 2019): 1–4. http://dx.doi.org/10.1155/2019/2986538.

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The case describes a 25-year-old Caucasian female diagnosed with Alexander’s disease (AxD) as an outpatient after extensive inpatient workup. Her presenting complaints included incontinence, clumsiness, seizures, dysphagia, and dysarthria. She was also found to have pancytopenia and dysautonomia. A full neurologic and hematologic workup yielded very little results, until a thorough literature search of her presenting complaints and radiologic findings pointed to adult-onset Alexander’s Disease. Alexander’s disease is a rare genetic leukodystrophy with a broad variety of presentations. Despite

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Mastrolilli, F., A. Benvenga, L. Di Biase, et al. "An Unusual Cause of Dementia: Essential Diagnostic Elements of Corticobasal Degeneration—A Case Report and Review of the Literature." International Journal of Alzheimer's Disease 2011 (2011): 1–6. http://dx.doi.org/10.4061/2011/536141.

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Corticobasal degeneration (CBD) is an uncommon, sporadic, neurodegenerative disorder of mid- to late-adult life. We describe a further example of the pathologic heterogeneity of this condition. A 71-year-old woman initially presented dysarthria, clumsiness, progressive asymmetric bradykinesia, and rigidity in left arm. Rigidity gradually involved ipsilateral leg; postural instability with falls, blepharospasm, and dysphagia subsequently developed. She has been previously diagnosed as unresponsive Parkinson's Disease. At our clinical examination, she presented left upper-arm-fixed-dystonia, spa

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Nardecchia, Francesca, Anna Caciotti, Teresa Giovanniello, et al. "3-Methylglutaconic Aciduria Type I Due to AUH Defect: The Case Report of a Diagnostic Odyssey and a Review of the Literature." International Journal of Molecular Sciences 23, no. 8 (2022): 4422. http://dx.doi.org/10.3390/ijms23084422.

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3-Methylglutaconic aciduria type I (MGCA1) is an inborn error of the leucine degradation pathway caused by pathogenic variants in the AUH gene, which encodes 3-methylglutaconyl-coenzyme A hydratase (MGH). To date, MGCA1 has been diagnosed in 19 subjects and has been associated with a variable clinical picture, ranging from no symptoms to severe encephalopathy with basal ganglia involvement. We report the case of a 31-month-old female child referred to our center after the detection of increased 3-hydroxyisovalerylcarnitine levels at newborn screening, which were associated with increased urina

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Sakaura, Hironobu, Yukihiko Yasui, Toshitada Miwa, Tomoya Yamashita, Kenji Ohzono, and Tetsuo Ohwada. "Cervical myelopathy caused by invagination of anomalous lamina of the axis." Journal of Neurosurgery: Spine 19, no. 6 (2013): 694–96. http://dx.doi.org/10.3171/2013.8.spine13325.

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The authors report a case of cervical myelopathy caused by invagination of the bilaterally separated lamina of the axis. They also present a literature review. The patient was a previously healthy 68-year-old man with a 1-year history of slowly progressive gait disturbance, right-hand clumsiness, and right dominant sensory disturbance in his trunk and extremities. Both MRI and CT showed that the spinal cord was markedly compressed at the C2–3 level, on the right side, by a deeply invaginated anomalous lamina of the axis. A bilaterally separated lamina was also visible. The patient underwent re

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Antonio Jesús, Morales Moreno, Castro Rey, Margarita del Carmen, et al. "A 19-Month-Old Spanish Boy with Anti-NMDAR Encephalitis: Case Report and Review of Literature." SVOA Neurology 5, no. 1 (2024): 21–25. http://dx.doi.org/10.58624/svoane.2024.05.0122.

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Background and Aim: The classic definition of acute encephalitis consists of altered consciousness associated with fever, seizures or focal neurological alterations on neuroimaging or electroencephalography. However, there are particularities that may provide a glimpse of the probably autoimmune versus infectious etiology of the same neurological picture. Case presentation: A 19-month-old male starts with motor clumsiness and refusal to ambulation and leg claudication in the context of febrile pharyngotonsillitis. Simultaneously, first episode of forced gaze’s lateralization and cephalic devia

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Salman, Michael S., and Kristin M. Ikeda. "The Syndrome of Infantile-Onset Saccade Initiation Delay." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 40, no. 2 (2013): 235–40. http://dx.doi.org/10.1017/s0317167100013792.

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Introduction:Infantile-onset saccade initiation delay (ISID), also known as congenital ocular motor apraxia, is characterized by the inability to initiate volitional horizontal saccades. Other abnormalities including developmental delay and ataxia have been reported. The frequency of these abnormalities is unknown. We performed a detailed review of the medical literature to quantify features of ISID.Methods:We searched the English medical literature for articles related to ISID from 1952 to 2010. Whenever possible, patients were excluded if they had acquired SID, Joubert syndrome or neurodegen

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Khattak, Shahzaib, Meryam Jan, Sara Warsi, and Sohail Khattak. "Chromosome 20p Partial De Novo Duplication Identified in a Female Paediatric Patient with Characteristic Facial Dysmorphism and Behavioural Anomalies." Case Reports in Genetics 2020 (July 11, 2020): 1–6. http://dx.doi.org/10.1155/2020/7093409.

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Copy number variations (CNVs) involving the JAG1 gene are rare and infrequently reported in the scientific literature. Recently, a generally healthy young patient presenting with a history of behavioural concerns was referred to us. Herein, we discuss the patient, a 7-year-old female possessing a 0.797 Mb microduplication within the short arm of chromosome 20 at band 12.2. The patient generates considerable curiosity due to the rarity of her case, which includes a de novo partial duplication involving the JAG1 gene. The patient exhibits a wide range of symptoms including facial dysmorphism (do

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13

Long, Alex. "Character and consensus in Plato's Protagoras." Cambridge Classical Journal 51 (2005): 1–20. http://dx.doi.org/10.1017/s1750270500000373.

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If we look to the Protagoras for philosophical lessons, it may seem an irritating patchwork of niggling argument, irrelevant digressions, false starts and downright fallacy. Read as a play in which the most outstanding and individual minds of a brilliant period meet and engage in a battle of wits, it will give a different impression. That is how it should be read. A serious discussion of the nature of virtue, and how it is acquired, must be left, as Protagoras said, for another occasion - and, we may add, for different company: it is not to be achieved in the competitive atmosphere of a public

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Grbović, Aleksandra, and Ksenija Stanimirov. "Nastavni pristup deci s vizuelnim disfunkcijama - praktična uputstva za usvajanje akademskih veština." Inovacije u nastavi 37, no. 4 (2024): 1–16. https://doi.org/10.5937/inovacije2404001g.

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The education of children with difficulties in visual functioning caused by lesions or dysfunctions in the central nervous system represents a significant challenge. This condition is called cerebral visual impairment and it is usually accompanied by normal ophthalmological results. Functional problems that occur in children can manifest as mild difficulties in directing visual attention, up to the complete inability to use vision effectively in certain situations. This variable behaviour of a child is (wrongly) interpreted as clumsiness, a lack of understanding and attention or it is attribut

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Kershenovich, Amir, Angela V. Price, Korgun Koral, Stan Goldman, and Dale M. Swift. "Failure to treat obstructive hydrocephalus with endoscopic third ventriculostomy in a patient with neurodegenerative Langerhans cell histiocytosis." Journal of Neurosurgery: Pediatrics 2, no. 5 (2008): 304–9. http://dx.doi.org/10.3171/ped.2008.2.11.304.

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The second most frequent central nervous system involvement pattern in Langerhans cell histiocytosis (LCH) is a rare condition documented in a number of reports called “neurodegenerative LCH” (ND-LCH). Magnetic resonance images confirming the presence of the disease usually demonstrate striking symmetric bilateral hyperintensities predominantly in the cerebellum, basal ganglia, pons, and/or cerebral white matter. The authors here describe for the first time in the literature a patient with ND-LCH and concomitant hydrocephalus initially treated using endoscopic third ventriculostomy (ETV). This

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16

Casall, Sergio. "Tragic irony in Ovid, Heroides 9 and 11." Classical Quarterly 45, no. 2 (1995): 505–11. http://dx.doi.org/10.1017/s0009838800043573.

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A dominant theme in the ninth of the Heroides, Deianira's letter to Hercules, is Deianira's indignation that Hercules has been defeated by a woman: first by Iole (especially in the first part of the letter: for example, lines 2, 5f., 1 If., 25f.); then by Omphale (especially in the section 103–18). The theme is exploited so insistently that Vessey, who regards the epistle as spurious, sees in this insistence a sign of the forger's clumsiness. consider the exploitation of the motive of‘victor victus’ in Heroides 9, on the contrary, as a strong sign of Ovidian authorship. From the very beginning

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Zaidi, Aisha Salman, Eric Christopher Burton, and Mitesh Lotia. "Leptomeningeal disease as a manifestation of CLL." Journal of Clinical Oncology 30, no. 15_suppl (2012): e17019-e17019. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e17019.

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e17019 Background: Chronic Lymphocytic Leukemia is a lymphoproliferative disorder which can have variable course from being indolent to aggressive. Reported annual incidence of Chronic Lymphocytic Leukemia is 3:100000. The most common manifestation is Lymphadenopathy and Leptomeningeal involvement is very rare with only a few reported cases in literature. Methods: This is an observational case report. Results: We report a case of 57 year old White male who presented with CNS disease as his first manifestation of CLL. He reported a 6 week history of cognitive decline with inability to perform c

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Shalimov, Sergey V. "Soviet-French Scientific Relationships in the Field of Molecular Biology and Biochemistry in the First Half of the 1970s." Novaya i Novejshaya Istoriya, no. 1 (May 23, 2024): 135–47. http://dx.doi.org/10.31857/s0130386424010115.

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In this article, the author analyses the scientific relationship between Soviet and French molecular biologists and biochemists in the first half of the 1970s. This cooperation is associated with the names of the prominent Russian and French scientists. The pioneers of this cooperation were Academicians Alexander Baev, Yuri Ovchinnikov, Alexander Spirin, Lev Kiselev, and other Soviet scientists, and Marianne Grunberg-Manago, François Gros, and Jean-Pierre Ebel, on the French side. Soviet-French scientific cooperation involved numerous research centers on both sides and manifested most vividly

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Struzik, Małgorzata, and Marta Gawlik. "The role of the nursing team in the care of patients with Kabuki syndrome." Medical Science Pulse 12, no. 3 (2018): 36–41. http://dx.doi.org/10.5604/01.3001.0012.5180.

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Background: Kabuki syndrome is a rare genetic condition characterised by pathological changes within all the systems of the body, but with variable gene expression. All the patients described in the literature so far have specific facial features resembling the masks of actors from the Japanese Kabuki Theatre and mild to moderate mental impairment. Diagnosis is made based by genetic testing for mutations of the KMT2D and KDM6A genes. Therapy is mainly based on symptomatic alleviation of the effects of mutation, rehabilitation and improvement of the quality of patients’ life. Then prognosis of

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Varga, Dragoș. "The Winning Formula. Convenții și stereotipuri ale romanului haiducesc în Mina haiduceasa. Fata codrilor de George Baronzi." Transilvania, December 1, 2021, 49–52. http://dx.doi.org/10.51391/trva.2021.11-12.06.

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The article aims to identify some of the peculiarities of the XIXth century outlaw novel in relation to the conventions and the stereotypes of the adventure novel, focusing on George Baronzi’s novel, Mina the Outlaw. The Girl of the Forests, an agreeable novel in spite of several narrative clumsiness. The novelty comes from the fact that the novel proposes a female character in the role of the hero, somehow accumulating the conventions and some narrative invariants specific to the outlaw novel, but also to the sentimental novel, the plot having as a starting point a love story. The novel is, t

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Irvine, Rebecca Eilish, and Arshia Ahmad. "Woodhouse-sakati syndrome with no reportable MRI findings: a case report." BMC Neurology 24, no. 1 (2024). http://dx.doi.org/10.1186/s12883-024-03865-z.

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Abstract Background Woodhouse-Sakati Syndrome (WSS) is a rare autosomal recessive condition caused by biallelic pathogenic variants in the DCAF17 gene, with fewer than 200 cases reported in the literature. Symptoms first emerge in middle-late adolescence with a spectrum of hypogonadal and progressive neurological features. Case presentation We present a case of WSS with no reportable T2-weighted, apparent diffusion coefficient mapping and susceptibility weighted MRI findings. This differs from cases reported in the current literature. Our patient developed abnormal movements in both legs, clum

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Perilli, Lorenzo, Gioia Mastromoro, Manuel Murciano, et al. "Myoclonic Epilepsy: Case Report of a Mild Phenotype in a Pediatric Patient Expanding Clinical Spectrum of KCNA2 Pathogenic Variants." Frontiers in Neurology 12 (February 1, 2022). http://dx.doi.org/10.3389/fneur.2021.806516.

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We report on the rare case of a male toddler presenting with myoclonic epilepsy characterized by daily episodes of upward movements of the eyebrows, and myoclonic jerks of both head and upper limbs. In addition, the child showed speech delay, tremors, and lack of motor coordination. Next Generation Sequencing analysis (NGS) performed in trio revealed in the proband the c.889C&gt;T de novo missense variant in the KCNA2 gene in heterozygous state. This is the first case of myoclonic epilepsy in a toddler due to a c.889C&gt;T KCNA2 missense variant. The patient was treated with valproic a

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Ji, Zhiguang, Liyan Wang, Ming Cai, Le Lu, and Hongbiao Wang. "Bibliometric analysis study on cognitive function in developmental coordination disorder from 2010 to 2022." Frontiers in Psychology 13 (December 6, 2022). http://dx.doi.org/10.3389/fpsyg.2022.1040208.

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ObjectiveTo identify the research hotspots on cognitive function in developmental coordination disorder (DCD) in recent years, predict the research frontier and development trend, and provide more perspectives for the study of the DCD population.MethodsUsing CiteSpace and VOSviewer software to draw charts, 1,082 pieces of literature about DCD and cognitive function in the Web of Science core collection database from 2010 to 2022 were visually analyzed.Results and conclusionInterest in the cognitive function of DCD has been on the rise in the past 10 years. Over 40 countries and regions, 117 in

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Phang, Michael Weng Lok, Sze Yuen Lew, Ivy Chung, William Kiong-Seng Lim, Lee Wei Lim, and Kah Hui Wong. "Therapeutic roles of natural remedies in combating hereditary ataxia: A systematic review." Chinese Medicine 16, no. 1 (2021). http://dx.doi.org/10.1186/s13020-020-00414-x.

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Abstract Background Hereditary ataxia (HA) represents a group of genetically heterogeneous neurodegenerative diseases caused by dysfunction of the cerebellum or disruption of the connection between the cerebellum and other areas of the central nervous system. Phenotypic manifestation of HA includes unsteadiness of stance and gait, dysarthria, nystagmus, dysmetria and complaints of clumsiness. There are no specific treatments for HA. Management strategies provide supportive treatment to reduce symptoms. Objectives This systematic review aimed to identify, evaluate and summarise the published li

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Kim, Soo Yeon, YoungKyu Shim, Young Joon Ko, et al. "Spectrum of movement disorders in GNAO1 encephalopathy: in-depth phenotyping and case-by-case analysis." Orphanet Journal of Rare Diseases 15, no. 1 (2020). http://dx.doi.org/10.1186/s13023-020-01594-3.

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Abstract Background GNAO1 encephalopathy is a rare neurodevelopmental disorder characterized by distinct movement presentations and early onset epileptic encephalopathy. Here, we report the in-depth phenotyping of genetically confirmed patients with GNAO1 encephalopathy, focusing on movement presentations. Results Six patients who participated in Korean Undiagnosed Disease Program were diagnosed to have pathogenic or likely pathogenic variants in GNAO1 using whole exome sequencing. All medical records and personal video clips were analyzed with a literature review. Three of the 6 patients were

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Scoppola, Chiara, Giorgio Magli, Marta Conti, et al. "CACNA1A-Linked Hemiplegic Migraine in GLUT 1 Deficiency Syndrome: A Case Report." Frontiers in Neurology 12 (May 31, 2021). http://dx.doi.org/10.3389/fneur.2021.679354.

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Background: Glucose-transporter-1 deficiency syndrome (GLUT1-DS), due to SLC2A1 gene mutation, is characterized by early-onset seizures, which are often drug-resistant, developmental delay, and hypotonia. Hemiplegic migraine (HM) is a rare form of migraine, defined by headache associated with transient hemiplegia, and can be caused by mutations in either CACNA1A, ATP1A2, or SCN1A. Paroxysmal movements, other transient neurological disorders, or hemiplegic events can occur in GLUT1-DS patients with a mild phenotype.Case: We report on a girl with GLUT1-DS, due to SLC2A1 mutation, with a mild phe

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Kaplan, Marina, Moira Mckniff, Stephanie M. Simone, Anna Callahan, and Tania Giovannetti. "Assessing Race Differences on Performance‐Based Assessment in Older Adults." Alzheimer's & Dementia 20, S4 (2024). https://doi.org/10.1002/alz.092697.

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AbstractBackgroundRace differences on cognitive tests have been widely reported and attributed to psychosocial factors. Cognitive assessment via performance‐based tests of everyday functioning may be less influenced by psychosocial factors, offering ecologically valid and less/unbiased measurement. This study examined differences between Black/African American and White older adults on traditional cognitive tests, self/informant report of everyday function, and a sensitive performance‐based test of everyday function called the Naturalistic Action Task (NAT). We predicted group differences on o

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Mastepak, Tatyana, та Elena Poleva. "ДЕТСТВО В СОЦИОКУЛЬТУРНОМ ПРОСТРАНСТВЕ РОМАНА В. НАБОКОВА «ДАР»". Tomsk state pedagogical university bulletin, № 3(209) (6 травня 2020). http://dx.doi.org/10.23951/1609-624x-2020-3-30-44.

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Введение. Обращение к исследованию детства в романе В. Набокова аргументировано рядом факторов: историко-культурными изменениями в начале ХХ века, вниманием к феномену детства в гуманитарном знании, значимостью детства в эстетике модернизма. Несмотря на то, что тема детства многократно становилась предметом набоковедческого анализа, оно не рассматривалось как часть социокультурного пространства в романе «Дар». Данная работа посвящена анализу социокультурной семантики этой темы и ее воплощения на уровне художественного пространства. Цель – исследовать социальные и культурные маркеры, характериз

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Munro, Andrew. "Discursive Resilience." M/C Journal 16, no. 5 (2013). http://dx.doi.org/10.5204/mcj.710.

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By most accounts, “resilience” is a pretty resilient concept. Or policy instrument. Or heuristic tool. It’s this last that really concerns us here: resilience not as a politics, but rather as a descriptive device for attempts in the humanities—particularly in rhetoric and cultural studies—to adequately describe a discursive event. Or rather, to adequately describe a class of discursive events: those that involve rhetorical resistance by victimised subjects. I’ve argued elsewhere (Munro, Descriptive; Reading) that Peircean semiosis, inflected by a rhetorical postulate of genre, equips us well t

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