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Dissertations / Theses on the topic 'Cluster mutation'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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1

Warkentin, Matthias. "Exchange Graphs via Quiver Mutation." Doctoral thesis, Universitätsbibliothek Chemnitz, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-153172.

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Inspired by Happel's question, whether the exchange graph and the simplicial complex of tilting modules over a quiver algebra are independent from the multiplicities of multiple arrows in the quiver, we study quantitative aspects of Fomin and Zelevinsky's quiver mutation rule. Our results turn out to be very useful in the mutation-infinite case for understanding combinatorial structures as the cluster exchange graph or the simplicial complex of tilting modules, which are governed by quiver mutation. Using a class of quivers we call forks we can show that any such quiver yields a tree in the ex
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2

Scott, J., I. Reiten, O. Iyama, and A. B. Buan. "Cluster structures for 2-Calabi-Yau categories and unipotent groups." Cambridge University Press, 2009. http://hdl.handle.net/2237/14400.

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3

Qian, Zheng. "Analysis of DNA damage induced by 2-hydroxy amino-1-methyl-6-phenyl-imidazol [4,5-b] pyridine (N-OH-PHIP) in the mutation cluster region of the human APC gene." Available to US Hopkins community, 2002. http://wwwlib.umi.com/dissertations/dlnow/3068198.

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4

Tran, Thi thanh tam. "Comparative and functional genome analysis of Acidithiobacillus bacteria." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4060.

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Les bactéries acidophiles du genre Acidithiobacillus joue un rôle important dans les activités industrielles de récupération des métaux au sein des sites miniers. Dans cette thèse, la séquence du génome de la bactérie psychro-tolerante Acidithiobacillus ferrivorans CF27 a été re-séquencée. L’analyse comparative du génome de CF27 et des autres bactéries du genre Acidithiobacillus a permis de montrer: (i) une synthénie conservée entre 2 clusters de tRNAs trouvés dans les génomes de At. ferrivorans CF27 et At. ferrooxidans ATCC 23270, et qui ont contribué à la redondance génique des tRNAs chez ce
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5

Chevallet, Mireille. "Étude du rôle structural et fonctionnel de la sous-unité NUO I de la NADH:ubiquinone oxydoréductase Rhodobacter capsulatus." Université Joseph Fourier (Grenoble ; 1971-2015), 1997. http://www.theses.fr/1997GRE10181.

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La nadh ubiquinone oxydoreductase ou complexe i est le premier element de la chaine respiratoire mitochondriale. Cette enzyme, dont le deficit est associe a plusieurs pathologies humaines, est un element essentiel du metabolisme energetique. Sa taille, sa localisation, sa complexite, le fait qu'elle soit codee a la fois par le genome mitochondrial et le genome nucleaire rendent son etude difficile. Pour ces raisons un modele bacterien a ete etudie : la nadh oxydoreductase de rhodobacter capsulatus qui ne contient que 14 sous-unites. La sous-unite nuo i du complexe i bacterien est remarquableme
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6

Lawson, John William. "On the combinatorics of quivers, mutations and cluster algebra exchange graphs." Thesis, Durham University, 2017. http://etheses.dur.ac.uk/12095/.

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Over the last 20 years, cluster algebras have been widely studied, with numerous links to different areas of mathematics and physics. These algebras have a cluster structure given by successively mutating seeds, which can be thought of as living on some graph or tree. In this way one can use various combinatorial tools to discover more about these cluster structures and the cluster algebras themselves. This thesis considers some of the combinatorics at play here. Mutation-finite quivers have been classified, with links to triangulations of surfaces and semi-simple Lie algebras, while comparati
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7

Gratz, Sira Helena [Verfasser]. "From finite to infinite : cluster algebras as colimits, and mutating torsion pairs in discrete cluster categrories / Sira Helena Gratz." Hannover : Technische Informationsbibliothek und Universitätsbibliothek Hannover (TIB), 2015. http://d-nb.info/1075261287/34.

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8

Tanaka, Daisuke. "GCKR mutations in Japanese families with clustered type 2 diabetes." Kyoto University, 2011. http://hdl.handle.net/2433/142543.

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9

Holler, Julia Pia Natascha. "Art und Häufigkeit von Mutationen im Wachstumshormon-Gen-Cluster bei Patienten mit einem isolierten Wachstumshormonmangel /." Giessen : VVB Laufersweiler, 2007. http://d-nb.info/987804154/04.

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10

Beka, Sylvia Enobong. "The genomics of Type 1 Diabetes susceptibility regions and effect of regulatory SNPs." Thesis, University of Hertfordshire, 2016. http://hdl.handle.net/2299/17200.

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Human complex diseases, like Diabetes and Cancer, affect many people worldwide today. Despite existing knowledge, many of these diseases are still not preventable. Complex diseases are known to be caused by a combination of genetic factors, as well as environmental and life style factors. The scope of this investigation covered the genomics of Type 1 Diabetes (T1D). There are 49 human genomic regions that are known to carry markers (disease-associated single nucleotide mutations) for T1D, and these were extensively studied in this research. The aim was to find out in how far this disease may b
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11

Fung, Wai-kei Vicky, and 馮慧琪. "Detection of non-deletional mutations of {221} globin gene cluster in patients with unexplained {221} thalassaemia and hereditarypersistence of fetal haemoglobin." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45160600.

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12

Figeac, Martin Delahaye Jean-Paul Varré Jean-Stéphane. "Étude de l'ordre des gènes clusters de gènes et algorithmique des réarrangements /." Villeneuve d'Ascq : Université des sciences et technologies de Lille, 2007. https://iris.univ-lille1.fr/dspace/handle/1908/637.

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13

Eudes, Richard. "Développements méthodologiques relatifs à l'attribution et à la prédiction des structures secondaires des protéines globulaires : classification structurale de mutations du transporteur CFTR, observées chez des patients atteints de mucoviscidose." Paris 6, 2006. http://www.theses.fr/2006PA066170.

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14

Karami, Yasaman. "Joint analysis of dynamically correlated networks and coevolved residue clusters : large-scale analysis and methods for predicting the effects of genetic disease associated mutations." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066375/document.

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Nous avons présenté COMMA, une méthode pour décrire et comparer les architectures dynamiques de différentes protéines. Il extrait propriétés dynamiques de ensembles conformationnels pour identifier les voies de communication, des chaînes de résidus liés par des interactions stables qui se déplacent ensemble, et cliques indépendants, des groupes de résidus qui fluctuent de manière concertée. Il fournit une description de l'infostery d'un complexe de protéines qui va au-delà des mesures au-delà de classiques de la façon dont une protéine se déplace ou change de forme. Nous avons montré l'efficac
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15

Karami, Yasaman. "Joint analysis of dynamically correlated networks and coevolved residue clusters : large-scale analysis and methods for predicting the effects of genetic disease associated mutations." Electronic Thesis or Diss., Paris 6, 2016. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2016PA066375.pdf.

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Nous avons présenté COMMA, une méthode pour décrire et comparer les architectures dynamiques de différentes protéines. Il extrait propriétés dynamiques de ensembles conformationnels pour identifier les voies de communication, des chaînes de résidus liés par des interactions stables qui se déplacent ensemble, et cliques indépendants, des groupes de résidus qui fluctuent de manière concertée. Il fournit une description de l'infostery d'un complexe de protéines qui va au-delà des mesures au-delà de classiques de la façon dont une protéine se déplace ou change de forme. Nous avons montré l'efficac
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16

Holroyd, Leo. "Mutagenicity of 5-bromouracil : quantum chemical study." Thesis, University of St Andrews, 2015. http://hdl.handle.net/10023/7063.

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This thesis describes a computational investigation of the mutagenicity of 5-bromouracil (BrU). In Chapter 1, three models of spontaneous and BrU-induced base mispairing (rare tautomer, wobble pair, and ion) are reviewed. Chapter 2 presents the computational techniques used: electronic structure methods (Hartree–Fock-based and density functional theory) and molecular dynamics. Chapter 3 presents optimisations of the keto and enol tautomers of BrU and uracil (U) in water clusters. The enol tautomer of BrU is found to be more stable than that of U. Chapter 4 is a molecular dynamics study of the
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17

Agbessi, Sonagnon Hervé. "Les pôles de compétitivité." Thesis, Paris 1, 2013. http://www.theses.fr/2013PA010319.

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Les mutations économiques induites par la mondialisation et la concurrence des pays émergents ont entraîné, en 2004, le lancement par l'Etat d'une politique industrielle articulée autour des pôles de compétitivité. Contrairement à la finalité redistributive de l'aménagement du territoire, les pôles de compétitivité n'ont pas été choisis selon une logique de type «aménagement volontaire de l'espace », ni déterminés par rapport à une vision qui irait dans le sens d'un rééquilibrage des potentiels de recherche sur le territoire national. La politique des pôles de compétitivité porte directement s
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18

Ma, Yi-Shing, and 馬逸興. "Oxidative Stress and Its Consequence in Human Cells Harboring MERRF-specific A8344G Mutation of mtDNA — Emphasis on Oxidative Damage to Enzymes Containing Fe-S Cluster." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/a2w222.

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博士<br>國立陽明大學<br>生化暨分子生物研究所<br>97<br>Increase in the production of reactive oxygen species (ROS) and decrease in mitochondrial protein synthesis have been implicated in the pathogenesis of myoclonic epilepsy with ragged-red fibers (MERRF) syndrome, which is mainly caused by the A8344G mutation at the tRNALys gene of mitochondrial DNA (mtDNA). In this study, the effect of this MERRF mutation on mitochondrial proteome was investigated by comparative proteomics. Mitochondria were isolated from human cybrids harboring wild-type mtDNA or mtDNA with a high proportion of the A8344G mutation. After
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19

Lin, Chen-Sheng, and 林俊昇. "Identification and Cluster Analysis of Sequence Signature Mutations over Time in Influenza A Viruses." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/67905197631155790232.

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碩士<br>國立交通大學<br>生醫工程研究所<br>103<br>Infuenza A viruses(IAV) caused epidemic several times a year, and sometimes a highly pathogenic IAV will cause a global outbreak of infection, for example the 2009 influenza A(H1N1) pandemic is one of the most destructive global pandemics in human history. Therefore, how to mitigating the severity of a new influenza pandemic is now a top global public health priority. In fact, the unique host range and two mechanisms for variation in viruses, antigenic drift and antigenic shift, makes the IAV is hard to predict. Identification of the host-associated genomic s
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