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Journal articles on the topic 'CN MOST'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Smutka, Luboš, Jaroslava Burianová, and Anna Belova. "The comparative advantage of Czech agricultural trade in relation to the most important trade partner countries in the period of 2008–2011." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 60, no. 7 (2012): 273–88. http://dx.doi.org/10.11118/actaun201260070273.

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The objective of the presented article is to analyze Czech agricultural trade as a whole and primarily trade in relation to the six key trade partners, with an emphasis on the identification of changes in its structure and competitiveness that occurred within the period of the years 2008–2011. On the basis of the results of the conducted analyses, it may be stated that the problematic period of the years 2008–2011 did not affect the development of Czech agricultural trade in an especially negative manner (commodity and territorial structure did not change significantly), whether in relation to

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2

Hanganu, Andreea-Raluca, Alexandru Constantin, Elena-Sonia Moise, et al. "Peripheral nervous system involvement associated with COVID-19. A systematic review of literature." PLOS ONE 18, no. 4 (2023): e0283827. http://dx.doi.org/10.1371/journal.pone.0283827.

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There is increasing evidence of both central and peripheral nervous system (PNS) involvement in COVID-19. We conducted this systematic literature review to investigate the characteristics, management and outcomes of patients with PNS, including the types and severity of cranial nerves (CN) involvement. We systematically searched on PubMed for studies reporting adult patients diagnosed with COVID-19 and PNS involvement until July 2021. From 1670 records, 225 articles matched the inclusion criteria, with a total of 1320 neurological events, in 1004 patients. There were 805 (61%) CN, 350 (26.5%)

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KAPPELER, STEFAN, ZAKARIA FARAH, and ZDENKO PUHAN. "Sequence analysis of Camelus dromedarius milk caseins." Journal of Dairy Research 65, no. 2 (1998): 209–22. http://dx.doi.org/10.1017/s0022029997002847.

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αs1-, αs2-, β- and κ-caseins from Somali camels (Camelus dromedarius) were purified by acid precipitation at pH 4·4, crudely separated into an α-CN and a β-CN fraction and further purified by reversed-phase HPLC. Fragments of tryptic digests were sequenced. Amino acid patterns obtained were used to screen a cDNA library constructed from mRNA from lactating udder tissue. Full length clones corresponding to the four caseins were sequenced. The numbers of residues in the sequences deduced were αs1-CN 207, αs2-CN 178, β-CN 217, κ-CN 162. Percentage similarity to bovine proteins was αs1-CN A 39, αs

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4

Park, Changsu, Sunita Ghosh, Feras Ayman Moria, et al. "Impact of timing of immunotherapy and cytoreductive nephrectomy on outcomes in metastatic renal cell carcinoma: Results from the CKCis database." Journal of Clinical Oncology 42, no. 4_suppl (2024): 416. http://dx.doi.org/10.1200/jco.2024.42.4_suppl.416.

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416 Background: Immunotherapy-based systemic treatment (ST) is the standard of care for most patients diagnosed with metastatic renal cell carcinoma (mRCC). Cytoreductive nephrectomy (CN) has historically shown benefit for select patients with mRCC but its role and timing are not well-understood in the era of immunotherapy. The primary objective of this study is to assess patient outcomes in patients who received ST only, CN followed by ST (CN-ST) and ST followed by CN (ST-CN). Methods: The Canadian Kidney Cancer information system (CKCis) database was queried to identify patients with de novo

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5

K Sethi, Nitin. "Trochlear nerve palsy in a boxer after a bout." MOJ Sports Medicine 4, no. 4 (2020): 109–10. http://dx.doi.org/10.15406/mojsm.2020.04.00105.

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Superior oblique palsy as a result of injury to the cranial nerve (CN) IV (trochlear nerve) is the most frequent isolated CN palsy due to its long intracranial course. Isolated CN IV palsy has not been reported in combat sports. We report here a case of isolated CN IV palsy occurring after a boxing bout. Isolated CN IV palsy may present very subtly in a combat sports athlete and ringside physicians should be aware of its clinical presentation.

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Gagnaire, Valerie, Alice Pierre, Daniel Molle, and Joelle Leonil. "Phosphopeptides interacting with colloidal calcium phosphate isolated by tryptic hydrolysis of bovine casein micelles." Journal of Dairy Research 63, no. 3 (1996): 405–22. http://dx.doi.org/10.1017/s0022029900031927.

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SummaryAfter extended tryptic hydrolysis of large bovine casein micelles, a mineral-rich peptide fraction was recovered by ultracentrifugation. Its mineral part contained 72% of the colloidal Ca and 49% of the colloidal Pi originally present in the native micelle. Colloidal nitrogenous components were also present, amounting to 27% of the original N content. They contained most of the phosphopeptides and 82% of the micellar phosphoseryl residues. These tryptic peptides were characterized by reversed-phase HPLC on-line electrospray ion source–mass spectrometry analysis. Among the peptides produ

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Petrovic-Prelevic, Irena, Antje Widmann, Heike Kahlert, Harm Wulff, and Fritz Scholz. "The Structure Investigation of Copper, Nickel and Iron Hexacyanometalates from Conventional X-Ray Powder Diffraction Data." Materials Science Forum 443-444 (January 2004): 345–48. http://dx.doi.org/10.4028/www.scientific.net/msf.443-444.345.

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The crystal structure of new Prussian blue analogue samples, KCu[Fe1-x Cox(CN)6], KNi[Fe1-x Cox(CN)6] and Fe[Fe1-x Cox(CN)6], was solved on the base of the model from Keggin and Miles [1] and refined by the Rietveld method [2] from conventional X-ray powder diffraction data. These compounds form mixed crystals for all Fe/Co ratios. The crystal structure of the KCu[Fe0.3Co0.7(CN)6], KNi[Fe0.3Co0.7(CN)6] and Fe[Fe0.8Co0.2(CN)6] is presented in detail. For both potassium containing compounds the disorder in the potassium arrangement is the most obvious characteristic.

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8

Kampshoff, Jesse L., Thomas H. Cogbill, Michelle A. Mathiason, Kara J. Rallies, and Lynn T. Martin. "Cranial Nerve Injuries are Associated with Specific Craniofacial Fractures after Blunt Trauma." American Surgeon 76, no. 11 (2010): 1223–27. http://dx.doi.org/10.1177/000313481007601121.

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Identification of cranial nerve (CN) injuries after blunt trauma is often delayed due to concomitant life-threatening trauma, altered mental status, and associated bony or soft tissue injuries. We hypothesized that specific craniofacial fracture (FX) patterns are associated with CN injuries, permitting earlier diagnosis. The trauma registry at a single institution was queried for all CN injuries and craniofacial FXs. Associations were determined by Fisher's exact test. Ninety CN injuries were identified in 59 patients. CN injuries were diagnosed on the day of admission in 24 (41%) patients. Th

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Kim, Jaeeun, Sanghwa Youm, Sooyoung Lee, and Kyunguk Jeong. "Clinical and laboratory characteristics of cashew nut allergy in Korean children." Allergologia et Immunopathologia 52, no. 3 (2025): 51–59. https://doi.org/10.15586/aei.v53i3.1289.

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Objective: Cashew nut (CN) allergy is becoming increasingly prevalent and represents a major cause of tree nut-induced anaphylaxis in Korean children. This study investigated the clinical characteristics and laboratory findings of CN allergy in Korean children. Patients and methods: Sixty-four children with a history of CN ingestion, who underwent serum CN-specific immunoglobulin E (CN-sIgE) measurements from January 2013 to February 2023, were enrolled through a retrospective medical record review. The demographic characteristics, clinical profiles, and laboratory findings were evaluated. Res

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Strauss, Gregory Paul, Farnaz Zamani Esfahlani, Brian Kirkpatrick, et al. "Network Analysis Reveals Which Negative Symptom Domains Are Most Central in Schizophrenia vs Bipolar Disorder." Schizophrenia Bulletin 45, no. 6 (2019): 1319–30. http://dx.doi.org/10.1093/schbul/sby168.

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Abstract Network analysis was used to examine how densely interconnected individual negative symptom domains are, whether some domains are more central than others, and whether sex influenced network structure. Participants included outpatients with schizophrenia (SZ; n = 201), a bipolar disorder (BD; n = 46) clinical comparison group, and healthy controls (CN; n = 27) who were rated on the Brief Negative Symptom Scale. The mutual information measure was used to construct negative symptom networks. Groups were compared on macroscopic network properties to evaluate overall network connectedness

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Tan, Wen Jia, Jen Feng Khor, Lloyd Ling та Yuk Feng Huang. "Misuse of Lambda (λ) in NRCS-CN Model". E3S Web of Conferences 65 (2018): 07006. http://dx.doi.org/10.1051/e3sconf/20186507006.

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Since 1954, the Soil Conservation Curve Number (SCS-CN) method is widely applied in hydrological field to predict the direct runoff resulting from event rainfall. Originally, the lambda value was fixed at 0.2. However, based on recent studies, the simplied SCS-CN method was unable to predict a consistent and accurate runoff amount. Most of the research studies in various countries claimed that lambda value was a variable and most likely should be less than 0.2. Most of the researchers applied either mean or median λ value directly without checking the statistics. Misuse of lambda value in SCS-

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Hoz, Samer S., Li Ma, Ahmed Muthana, et al. "Cranial nerve palsies and intracranial aneurysms: A narrative review of patterns and outcomes." Surgical Neurology International 15 (August 9, 2024): 277. http://dx.doi.org/10.25259/sni_531_2024.

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Background: Cranial nerve palsy (CNP) in patients with intracranial aneurysms (IAs) can impose significant burdens on a patient’s quality of life. The literature has a paucity of reviews addressing patterns of overall reported cranial nerve (CN) involvement and outcomes in patients with IA. Methods: The literature systematically reviewed CNP at presentation in the setting of IA using PubMed, Web-of-Science, and Scopus according to the PRISMA guidelines. Results: Fifty-two studies reported a total of 513 patients with IA and 630 CNPs observed at presentation: oculomotor (58.25%), abducent (15.8

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Cazzoletti, P., E. F. van Dishoeck, R. Visser, S. Facchini, and S. Bruderer. "CN rings in full protoplanetary disks around young stars as probes of disk structure." Astronomy & Astrophysics 609 (January 2018): A93. http://dx.doi.org/10.1051/0004-6361/201731457.

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Aims. Bright ring-like structure emission of the CN molecule has been observed in protoplanetary disks. We investigate whether such structures are due to the morphology of the disk itself or if they are instead an intrinsic feature of CN emission. With the intention of using CN as a diagnostic, we also address to which physical and chemical parameters CN is most sensitive. Methods. A set of disk models were run for different stellar spectra, masses, and physical structures via the 2D thermochemical code DALI. An updated chemical network that accounts for the most relevant CN reactions was adop

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14

Khodadoost, Baback. "Observation of a Most Phenomenal Computed Calligraphy in Quran." Computer and Information Science 9, no. 3 (2016): 42. http://dx.doi.org/10.5539/cis.v9n3p42.

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<span style="font-size: 10pt; font-family: 'Times New Roman','serif'; color: black; mso-bidi-font-size: 9.0pt; mso-fareast-font-family: 宋体; mso-themecolor: text1; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;" lang="EN-US">Observation of a multifaceted mathematical-computational structure of Quran through analysis of its letter and word frequencies and important implications of such observations have been extensively explained and discussed in a recent article: </span><span style="font-size: 10pt; font-family: 'Times Ne

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15

Shikhaliyev, Ramiz. "A method for intelligent scheduling of computer networks monitoring." Problems of Information Technology 13, no. 1 (2022): 38–42. http://dx.doi.org/10.25045/jpit.v13.i1.05.

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To ensure the efficiency of management, the security of computer networks (CN), as well as to ensure the required level of quality of service for network applications, accurate and up-to-date information on the state of the CN is required. This information can be obtained through continuous active monitoring of the quantitative characteristics of the CN. Thus, active monitoring becomes an important tool for ensuring the efficiency of management and security of the CN. However, continuous active monitoring, especially of large networks, can lead to congestion of network channels, which can redu

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Wang, Lu, Na Cheng, Ping Wang, et al. "A novel peptide exerts potent immunosuppression by blocking the two-site interaction of NFAT with calcineurin." Journal of Biological Chemistry 295, no. 9 (2020): 2760–70. http://dx.doi.org/10.1074/jbc.ra119.010254.

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The calcineurin/nuclear factor of activated T cell (CN/NFAT) signaling pathway plays a critical role in the immune response. Therefore, inhibition of the CN/NFAT pathway is an important target for inflammatory disease. The conserved PXIXIT and LXVP motifs of CN substrates and targeting proteins have been recognized. Based on the affinity ability and inhibitory effect of these docking sequences on CN, we designed a bioactive peptide (named pep3) against the CN/NFAT interaction, which has two binding sites derived from the RCAN1-PXIXIT motif and the NFATc1-LXVP motif. The shortest linker between

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Juvvadi, Praveen R., Benjamin G. Bobay, D. Christopher Cole, Monaf Awwa, and William J. Steinbach. "Calcineurin Inhibitor CN585 Exhibits Off-Target Effects in the Human Fungal Pathogen Aspergillus fumigatus." Journal of Fungi 8, no. 12 (2022): 1281. http://dx.doi.org/10.3390/jof8121281.

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Calcineurin (CN) is an attractive antifungal target as it is critical for growth, stress response, drug resistance, and virulence in fungal pathogens. The immunosuppressive drugs, tacrolimus (FK506) and cyclosporin A (CsA), are fungistatic and specifically inhibit CN through binding to their respective immunophilins, FK506-binding protein (FKBP12), and cyclophilin (CypA). We are focused on CN structure-based approaches for the development of non-immunosuppressive FK506 analogs as antifungal therapeutics. Here, we examined the effect of the novel CN inhibitor, CN585, on the growth of the human

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Rakhimova, A. I. "Chaotic and frequently hypercyclic operators in the weighted space of entire functions." Mathematics and Theoretical Computer Science 2, no. 2 (2024): 84–106. http://dx.doi.org/10.26907/2949-3919.2024.2.84-106.

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We study the issues of chaoticity and frequently hypercyclicity of various operators in the weighted space Fφ(Cn), defined as the projective limit of Banach spaces. Theorems 8–13 consider the cases of differentiation and shift operators, as well as their compositions in Fφ(Cn). For linear continuous operators commuting with differentiation, Theorem 14 shows that they are chaotic in Fφ(Cn). In Theorem 15, such operators are proved to be frequently hypercyclic in Fφ(Cn), and also are the most important consequences of these statements are indicated.

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Szatylowicz, Halina, Anna Jezuita, Paulina H. Marek, and Tadeusz M. Krygowski. "Substituent effects on the stability of the four most stable tautomers of adenine and purine." RSC Advances 9, no. 54 (2019): 31343–56. http://dx.doi.org/10.1039/c9ra04615a.

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Substituent effects at the C2-, C8- and N-positions of adenine and purine in their four the most stable tautomers are examined using substituents of varying electronic properties: NO<sub>2</sub>, CN, CHO, Cl, F, H, Me, OMe, OH and NH<sub>2</sub>.

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Jung, Seung-Hyun, Youn Jin Choi, Min Sung Kim, et al. "Distinct genomic profiles of gestational choriocarcinoma, a unique cancer of pregnant tissues." Experimental & Molecular Medicine 52, no. 12 (2020): 2046–54. http://dx.doi.org/10.1038/s12276-020-00544-0.

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AbstractLittle is known about genomic alterations of gestational choriocarcinoma (GC), unique cancer that originates in pregnant tissues, and the progression mechanisms from the nonmalignant complete hydatidiform mole (CHM) to GC. Whole-exome sequencing (20 GCs) and/or single-nucleotide polymorphism microarray (29 GCs) were performed. We analyzed copy-neutral loss-of-heterozygosity (CN-LOH) in 29 GCs that exhibited androgenetic CN-LOHs (20 monospermic, 8 dispermic) and no CN-LOH (one with NLRP7 mutation). Most GCs (25/29) harboring recurrent copy number alterations (CNAs) and gains on 1q21.1-q

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Strapazan, Carina, Ioan-Aurel Irimuș, Gheorghe Șerban, Titus Cristian Man, and Laura Sassebes. "Determination of Runoff Curve Numbers for the Growing Season Based on the Rainfall–Runoff Relationship from Small Watersheds in the Middle Mountainous Area of Romania." Water 15, no. 8 (2023): 1452. http://dx.doi.org/10.3390/w15081452.

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The NRCS-CN (Natural Resources Conservation Service curve number) method, developed by the USDA (U.S. Department of Agriculture) is among the most widely used for the estimation of surface runoff from watersheds. Ever since its introduction in the 1950s, although it has been used to a great extent by engineers and hydrologists, the applicability of the original procedure used to determine its main parameter, the curve number (CN), to various regions with diverse environmental conditions, is still subject to many uncertainties and debates. This study presents a comparative analysis of different

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Liu, Yvlu, Bing Geng, Guoyi Wu, et al. "Effect of Combined Application of Lanthanum-Based Capping Material and Biochemical Oxidant on Control of Internal Phosphorus." Water 16, no. 5 (2024): 641. http://dx.doi.org/10.3390/w16050641.

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In situ capping and biochemical oxidation are two of the most commonly used methods for internal phosphorus (P) control, but there are few studies on the combined use of these two methods. In this study, two lanthanum (La)-based materials, La-modified bentonite (LMB) and the La-modified attapulgite and chitosan composite (LMA&C), were combined with calcium nitrate (CN) to investigate the effect on sediment P control. Results showed that SRP removal rates by LMB+CN and LMA&C+CN were much higher than that by LMB, LMA&C and CN alone. LMB+CN and LMA&C+CN decreased DGT-labile P flux

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Illanes, Alejandro. "Hereditarily indecomposable Hausdorff continua have unique hyperspaces 2X and Cn(X)." Publications de l'Institut Math?matique (Belgrade) 89, no. 103 (2011): 49–56. http://dx.doi.org/10.2298/pim1103049i.

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Let X be a Hausdorff continuum (a compact connected Hausdorff space). Let 2X (respectively, Cn(X)) denote the hyperspace of nonempty closed subsets of X (respectively, nonempty closed subsets of X with at most n components), with the Vietoris topology. We prove that if X is hereditarily indecomposable, Y is a Hausdorff continuum and 2X (respectively Cn(X)) is homeomorphic to 2Y (respectively, Cn(Y )), then X is homeomorphic to Y.

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Ibrahim, Salma, Babikir Brasi, Qingchun Yu, and Magdi Siddig. "Curve number estimation using rainfall and runoff data from five catchments in Sudan." Open Geosciences 14, no. 1 (2022): 294–303. http://dx.doi.org/10.1515/geo-2022-0356.

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Abstract The United States Natural Resources Conservation Services Curve Number (NRCS-CN) method uses the CN and rainfall to calculate runoff. However, there are still some uncertainties in the method, such as choosing the most appropriate CN value. Therefore, this study attempts to evaluate the effectiveness of using the NRCS-CN method to estimate the runoff of five catchments in Sudan. For each catchment, CN values were obtained from the number of observed rainfall-runoff events using the NRCS table, arithmetic mean, median, and geometric mean methods. For each method, Nash–Sutcliffe efficie

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Makiabadi, Batoul, Mohammad Zakarianezhad, and Shahin Mohammadzamani. "Theoretical Study of CN Radicals Chemisorption on the Electronic Properties of BC₂N Nanotube." Journal of Nano Research 48 (July 2017): 38–48. http://dx.doi.org/10.4028/www.scientific.net/jnanor.48.38.

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In this work, we have investigated the adsorption behavior of the CN radicals on electronic properties of BC2N nanotube (BC2NNT) by means of the B3LYP hybrid density functional method using 6-31G(d) basis set. The results show that CN radicals can be chemically adsorbed on the nanotube. Based on the energy analysis, the most stable position of CN radical on the nanotube is C1 site. Also, the C-side complexes are more stable than the N-side complexes. We investigated the effects of CN radicals adsorption on the electronic properties of the BC2N nanotube. According to our calculations, band gap

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Rives, Taylor A., Abu Saleh Mosa Faisal, Jinpeng Liu, et al. "Comparison of the clinical and genomic profiles of endometrial cancer in Appalachian and non-Appalachian patients." Journal of Clinical Oncology 42, no. 16_suppl (2024): 5591. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.5591.

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5591 Background: Kentucky has the highest incidence and mortality from gynecologic cancer in the United States, and the incidence of endometrial cancer (EC) in the Kentucky Appalachian (AP) population is even higher than non-Appalachian (non-AP). The purpose of this study is to compare demographics, molecular profiles, and outcomes between AP and non-AP populations. Methods: Using the Total Cancer Care prospective cohort study, we evaluated 836 women with EC, 40 AP (4.8%), 700 non-AP (83.7%), and 96 with unknown residence (11.5%). We used descriptive statistics and univariate analyses to compa

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Coello, Alejandro Fernández, Andreu Gabarrós Canals, Juan Martino Gonzalez, and Juan José Acebes Martín. "Cranial nerve injury after minor head trauma." Journal of Neurosurgery 113, no. 3 (2010): 547–55. http://dx.doi.org/10.3171/2010.6.jns091620.

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Object There are no specific studies about cranial nerve (CN) injury following mild head trauma (Glasgow Coma Scale Score 14–15) in the literature. The aim of this analysis was to document the incidence of CN injury after mild head trauma and to correlate the initial CT findings with the final outcome 1 year after injury. Methods The authors studied 49 consecutive patients affected by minor head trauma and CN lesions between January 2000 and January 2006. Detailed clinical and neurological examinations as well as CT studies using brain and bone windows were performed in all patients. Based on

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Takei, Hidehiro, Yummy Nguyen, Vidya Mehta, Murali Chintagumpala, Robert C. Dauser, and Adekunle M. Adesina. "Low-level copy gain versus amplification of myc oncogenes in medulloblastoma: utility in predicting prognosis and survival." Journal of Neurosurgery: Pediatrics 3, no. 1 (2009): 61–65. http://dx.doi.org/10.3171/2008.10.peds08105.

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Object Medulloblastoma (MB) is a malignant embryonal tumor of the cerebellum. Amplification of c-myc or N-myc is infrequently identified and, when present, is often associated with the large cell/anaplastic (LC/A) phenotype. The frequency of low-level copy gain of myc oncogenes and its relationship to prognosis of MB has not been explored. Methods Archival cases of MB were histologically reviewed and classified into 3 major subtypes: classic, nodular, and LC/A. Using quantitative real-time polymerase chain reaction (PCR), the authors analyzed 58 cases with a pure histological subtype for the c

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Bustamante, Bethany, Risha Sinha, Briana Rice, et al. "Clinical Implications of Genomic Loss of Heterozygosity in Endometrial Carcinoma." JCO Precision Oncology, no. 5 (June 2021): 1013–23. http://dx.doi.org/10.1200/po.20.00393.

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PURPOSE Homologous recombination deficiency, identified by homologous recombination deficiency gene alterations or high percentage of genome-wide loss of heterozygosity (gLOH), is associated with improved prognosis, platinum sensitivity (PS), and poly (ADP-ribose) polymerase inhibitor response in high-grade ovarian cancer. Since the copy number–high (CN-H) endometrial cancer molecular subtype (EC-MS) shares molecular features with high-grade ovarian cancer, our aim was to assign EC-MS on the basis of comprehensive genomic profiling (CGP) results and evaluate the gLOH status with clinical behav

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Beattie, JK, and GA Polyblank. "Copper-Catalyzed Oxidation of Cyanide by Peroxide in Alkaline Aqueous Solution." Australian Journal of Chemistry 48, no. 4 (1995): 861. http://dx.doi.org/10.1071/ch9950861.

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The oxidation of cyanide by peroxide in alkaline aqueous solution is catalysed by copper complexes. In the presence of excess cyanide, copper(II) is reduced to form the tricyanocuprate (I) complex. The cyanogen oxidation product is hydrolysed with disproportionation to cyanate and cyanide:2CuII+2CN-→ 2CuI+(CN)2(CN)2+2OH- → OCN-+CN-+H2OCuI+3CN- ↔ Cu(CN)32-The stoichiometry and kinetics of the catalysed oxidation have been investigated. Hydrogen peroxide oxidizes coordinated cyanide with a rate that is first order in peroxide and first order in copper but independent of cyanide concentration in

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Revilla, Isabel, José M. Rodríguez-Nogales, and Ana M. Vivar-Quintana. "Effect of somatic cell counts on ewes' milk protein profile and cheese-making properties in different sheep breeds reared in Spain." Journal of Dairy Research 76, no. 2 (2009): 210–15. http://dx.doi.org/10.1017/s0022029909004002.

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Bulk tank ewe's milks from Assaf, Castellana and Churra breeds categorized within three different Somatic Cell Count (SCC) groups (LSCC: <500 000; MSCC: 1 000 000 to 1 500 000; and HSCC: 2 500 000 to 3 000 000 cells ml−1) were used to investigate changes in capillary electrophoresis protein profiles and cheese-making properties. The results do not reveal a significant effect of SCC on total casein contents, because the sum of β-caseins decreased as SCC increased; no statistically significant differences were observed for the sum of α-caseins, and the values of κ-casein were higher in the HS

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Park, Changsu Lawrence, Feras Ayman Moria, Sunita Ghosh, et al. "Impact of Timing of Immunotherapy and Cytoreductive Nephrectomy in Metastatic Renal Cell Carcinoma: Real-World Data on Survival Outcomes from the CKCis Database." Current Oncology 31, no. 8 (2024): 4704–12. http://dx.doi.org/10.3390/curroncol31080351.

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Immunotherapy-based systemic treatment (ST) is the standard of care for most patients diagnosed with metastatic renal cell carcinoma (mRCC). Cytoreductive nephrectomy (CN) has historically shown benefit for select patients with mRCC, but its role and timing are not well understood in the era of immunotherapy. The primary objective of this study is to assess outcomes in patients who received ST only, CN followed by ST (CN-ST), and ST followed by CN (ST-CN). The Canadian Kidney Cancer information system (CKCis) database was queried to identify patients with de novo mRCC who received immunotherap

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Lou, Jiahui, Lihong Wang, Yaqiong Huang, Jun Xing, and Xiaojie Yang. "Boosting Photocatalytic Performance of ZnO Nanowires via Building Heterojunction with Conjugated 2,4,6-Triaminopyrimidine-g-C3N4." Molecules 29, no. 16 (2024): 3716. http://dx.doi.org/10.3390/molecules29163716.

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Photocatalysis is one of the most effective ways to solve environmental problems by solving pollutants. This article designed and prepared a conjugated system of 2,4,6-triaminopyrimidine-g-C3N4 (TAP-CN) to modify ZnO NWs. We systematically studied the photocatalytic performance of ZnO NWs modified with different ratios of TAP-CN. The results showed that 9 wt% TAP-CN-30/ZnO NWs had the best degradation effect on Rhodamine B dye. The degradation rate was 99.36% in 80 min. The excellent degradation performance was attributed to the TAP-CN conjugated system promoting photo-generated charge transfe

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Lin, Jin-Yi, Chien-Lin Liu, Zheng-Yan Dai, et al. "Clinical Outcomes of Severe Rhinosinusitis Complicated with Cavernous Sinus Syndrome." Journal of Clinical Medicine 13, no. 8 (2024): 2420. http://dx.doi.org/10.3390/jcm13082420.

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Background: Various diseases involving the cavernous sinus can cause a condition called cavernous sinus syndrome (CSS), which is characterized by ophthalmoplegia or sensory deficits over the face resulting from the compression effect of internal structure. While tumor compression is the most reported cause of CSS, statistical data on CSS caused by infections are limited. Its risk factors, treatment methods, and clinical outcomes are not well-documented. Methods: In this retrospective study, we reviewed the data of patients admitted to a tertiary medical center from 2015 to 2022 with a diagnosi

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Liu, Zimin, Mingpeng Shi, Xiaoxiao Li, et al. "HER2 copy number as predictor of disease-free survival in HER2-positive resectable gastric adenocarcinoma." Journal of Cancer Research and Clinical Oncology 147, no. 5 (2021): 1315–24. http://dx.doi.org/10.1007/s00432-021-03522-9.

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Abstract Purpose The identification of HER2 overexpression in a subset of gastric adenocarcinoma (GA) patients represents a significant step forward in unveiling the molecular complexity of this disease. The predictive and prognostic value of HER2 amplification in advanced HER2 inhibitor-treated GA patients has been investigated. However, its predictive value in resectable patients remains elusive. Methods We enrolled 98 treatment-naïve resectable Chinese GA patients with HER2 overexpression assessed using IHC. Capture-based targeted sequencing using a panel consisting of 41 gastrointestinal c

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Skjervold, Anette H., Marit Valla, Borgny Ytterhus, and Anna M. Bofin. "PAK1 copy number in breast cancer—Associations with proliferation and molecular subtypes." PLOS ONE 18, no. 6 (2023): e0287608. http://dx.doi.org/10.1371/journal.pone.0287608.

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Introduction P21-activated kinase 1 (PAK1) is known to be overexpressed in several human tumour types, including breast cancer (BC). It is located on chromosome 11 (11q13.5-q14.1) and plays a significant role in proliferation in BC. In this study we aimed to assess PAK1 gene copy number (CN) in primary breast tumours and their corresponding lymph node metastases, and associations between PAK1 CN and proliferation status, molecular subtype, and prognosis. In addition, we aimed to study associations between CNs of PAK1 and CCND1. Both genes are located on the long arm of chromosome 11 (11q13). M

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LABRUNE, P. H., M. ODIÈVRE, A. MYARA, F. TRIVIN, and J. FRANCOUAL. "Cerebellar Symptoms as the Presenting Manifestations of Bilirubin Encephalopathy in Children with Crigler-Najjar Type I Disease." Pediatrics 89, no. 4 (1992): 768–70. http://dx.doi.org/10.1542/peds.89.4.768.

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Crigler-Najjar (CN) disease is a rare metabolic disorder characterized by a permanent deficiency in hepatic bilirubin UDPglucuronate β-d-glucuronosyl-transferase (UDPG-T, EC 2.1.4.17) activity. Since 1969, patients affected by this disease have been classified in two groups: in the first group (CN type I), the serum bilirubin concentration does not decrease under treatment with phenobarbital although it does so dramatically in the second group (CN type II).1,2 Despite the use of phototherapy and cholestyramine to avoid bilirubin neurotoxicity, patients affected by CN type I disease are at perm

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Vijai Bharathy, P., Q. Yang, and D. Nataraj. "Microstructure and Adhesion Properties of a-CN and Ti/a-CN Nanocomposite Thin Films Prepared by Hybrid Ion Beam Deposition Technique." Advanced Materials Research 938 (June 2014): 36–39. http://dx.doi.org/10.4028/www.scientific.net/amr.938.36.

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Carbon based materials have attracted much for its unique surface microstructure and nanomechanical properties among researchers. In this study, the influence of microstructure on the nanomechanical properties of thin carbon based films was studied in detail. For which amorphous Carbon nitride (a-CN) and Titanium incorporated amorphous Carbon nitride (Ti/a-CN) thin films were prepared with a thickness of less than 100 nm using hybrid ion beam deposition technique. The incorporation of Ti into the a-CN matrix greatly modified the sp3/sp2 hybridized bonding ratio and it is reflected in the mecha

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Holdefer, R. N., J. C. Houk, and L. E. Miller. "Movement-Related Discharge in the Cerebellar Nuclei Persists After Local Injections of GABAA Antagonists." Journal of Neurophysiology 93, no. 1 (2005): 35–43. http://dx.doi.org/10.1152/jn.00603.2004.

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Limb movement-related neurons in the cerebellar nuclei (CN) typically produce bursts of discharge in association with movement. Consequently, given the inhibitory nature of the Purkinje cell (PC) projection to CN, it is puzzling that only a minority of movement-related PCs pause; the majority burst. Some of the movement-related CN activity may be the result of excitation from collaterals of mossy and climbing fiber projections to the cerebellar cortex. The only other input to CN is diffuse and neuromodulatory, from locus ceruleus and raphe nuclei. To investigate the role of the excitatory moss

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Walter, Wencke, Heiko Müller, Claudia Haferlach, et al. "Copy-Neutral Loss-of-Heterozygosity Adds Diagnostic and Prognostic Information to the Molecular Profiling of Hematological Malignancies." Blood 138, Supplement 1 (2021): 2228. http://dx.doi.org/10.1182/blood-2021-152195.

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Abstract Background: Copy-neutral loss-of-heterozygosity (CN-LOH) - not detectable by chromosome banding analysis - is gaining importance as a prognostic factor and can either cause the duplication of an activating mutation in an oncogene, the deletion of a tumor suppressor gene or the gain/loss of specific methylated regions. However, examination for possible CN-LOH in hematological diagnostics is at present not routinely performed and, hence, data regarding the occurrence of CN-LOH across different entities as well as the association of relevant genes is limited. Aim: (1) Frequency assessmen

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Curcio, Manuela, Annafranca Farfalla, Federica Saletta, et al. "Functionalized Carbon Nanostructures Versus Drug Resistance: Promising Scenarios in Cancer Treatment." Molecules 25, no. 9 (2020): 2102. http://dx.doi.org/10.3390/molecules25092102.

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Carbon nanostructures (CN) are emerging valuable materials for the assembly of highly engineered multifunctional nanovehicles for cancer therapy, in particular for counteracting the insurgence of multi-drug resistance (MDR). In this regard, carbon nanotubes (CNT), graphene oxide (GO), and fullerenes (F) have been proposed as promising materials due to their superior physical, chemical, and biological features. The possibility to easily modify their surface, conferring tailored properties, allows different CN derivatives to be synthesized. Although many studies have explored this topic, a compr

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Illanes, Alejandro, and Verónica Martínez-de-la-Vega. "Irreducibility of strong size levels." Mathematica Slovaca 74, no. 2 (2024): 521–25. http://dx.doi.org/10.1515/ms-2024-0039.

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Abstract Given a continuum X, Cn (X) denotes the hyperspace of nonempty closed subsets of X with at most n components. A strong size level is a subset of the form σ −1(t), where σ is a strong size map for Cn (X) and t ∈ (0, 1]. In this paper, answering a question by Capulín-Pérez, Fuentes-Montes de Oca, Lara-Mejía and Orozco-Zitli, we prove that for each n ≥ 2, no strong size level for Cn (X) is irreducible.

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Dannenmann, Benjamin, Benedikt Oswald, Malte U. Ritter, et al. "Transcriptome Analysis of Severe Congenital Neutropenia Associated Leukemia with Different Types of RUNX1 Mutations in an iPSC-Based Model." Blood 136, Supplement 1 (2020): 23–24. http://dx.doi.org/10.1182/blood-2020-142524.

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Co-acquisition of CSF3R and RUNX1 mutations is the most frequent combination of acquired genetic abnormalities found in AML and MDS cases associated with severe congenital neutropenia (CN). Using the iPSC-based model for CN-associated leukemia, we compared the outcomes of RUNX1 missense mutations and RUNX1 haploinsufficiency by means of hematopoietic differentiation and transcriptome analysis. We generated iPSC lines from 2 CN/AML patients harboring ELANE mutations p.C151Y or p.G214R (CN1 and CN2, accordingly). CN/AML iPSC clones of CN patient 1 were generated from leukaemia cells with CSF3R p

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Ahmed, Faheem, Thangavelu Kokulnathan, Ahmad Umar, et al. "Zinc Oxide/Phosphorus-Doped Carbon Nitride Composite as Potential Scaffold for Electrochemical Detection of Nitrofurantoin." Biosensors 12, no. 10 (2022): 856. http://dx.doi.org/10.3390/bios12100856.

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Herein, we present an electrocatalyst constructed by zinc oxide hexagonal prisms/phosphorus-doped carbon nitride wrinkles (ZnO HPs/P-CN) prepared via a facile sonochemical method towards the detection of nitrofurantoin (NF). The ZnO HPs/P-CN-sensing platform showed amplified response and low-peak potential compared with other electrodes. The exceptional electrochemical performance could be credited to ideal architecture, rapid electron/charge transfer, good conductivity, and abundant active sites in the ZnO HPs/P-CN composite. Resulting from these merits, the ZnO HPs/P-CN-modified electrode de

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Kenney, M. J., S. M. Barman, G. L. Gebber, and S. Zhong. "Differential relationships among discharges of postganglionic sympathetic nerves." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 260, no. 6 (1991): R1159—R1167. http://dx.doi.org/10.1152/ajpregu.1991.260.6.r1159.

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The relationships among the simultaneously recorded discharges of as many as four postganglionic sympathetic nerves were studied with coherence and phase spectral analyses in baroreceptor-denervated cats. Discharges were recorded from the inferior cardiac (CN), vertebral (VN), and renal (RN) nerves. Most of the power in sympathetic nerve discharge was less than 6 Hz, and the discharges of any two nerves coherred over a frequency band generally between 0 and 15 Hz. Peak coherence occurred between 2 and 6 Hz in most cases. Our most important observations are as follows. 1) Coherence values were

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van Peer, Sophie E., Corine J. H. Pleijte, Ronald R. de Krijger, et al. "Clinical and Molecular Characteristics and Outcome of Cystic Partially Differentiated Nephroblastoma and Cystic Nephroma: A Narrative Review of the Literature." Cancers 13, no. 5 (2021): 997. http://dx.doi.org/10.3390/cancers13050997.

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In children presenting with a predominantly cystic renal tumor, the most likely diagnoses include cystic partially differentiated nephroblastoma (CPDN) and cystic nephroma (CN). Both entities are rare and limited information on the clinical and molecular characteristics, treatment, and outcome is available since large cohort studies are lacking. We performed an extensive literature review, in which we identified 113 CPDN and 167 CN. The median age at presentation for CPDN and CN was 12 months (range: 3 weeks–4 years) and 16 months (prenatal diagnosis–16 years), respectively. No patients presen

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Bang, Yoon Hyun, Eun Gyeong Song, Younghye Lee, and Ki Hyun Ryu. "Occurrence of Viruses and Viroids in Chrysanthemum Plants (Dendranthema morifolium) Cultivated in Yesan-gun, Chungcheongnam-do in Korea." Research in Plant Disease 28, no. 4 (2022): 237–44. http://dx.doi.org/10.5423/rpd.2022.28.4.237.

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Chrysanthemum plants are one of the most economically important plants in South Korea. Both virus and viroid can cause diseases and economic damage to the plants. In this study, we investigated the detection of seven viruses and two viroids in 350 chrysanthemum plants cultivated in Yesan-gun, Chungcheongnam-do. Two viruses, chrysanthemum virus B (CVB) and tomato aspermy virus (TAV), and two viroids, chrysanthemum chlorotic mottle viroid (CChMVd) and chrysanthemum stunt viroid (CSVd), were detected in this study. The two viruses were detected in six samples and one sample, respectively. The two

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Tamyiz, Muchammad, Mohd Hanif Mohd Pisal, and Atik Widiyanti. "The Zinc Ferrite Decorated Unexfoliated Graphitic Carbon Nitride for Effective Antibiotic Degradation under Visible Light." Journal of Biomimetics, Biomaterials and Biomedical Engineering 67 (January 15, 2025): 37–43. https://doi.org/10.4028/p-ubwn3i.

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The antibiotic pollutant treatment in wastewater using conventional method remains a challenge. One of the most fluoroquinolone antibiotics family used by human and animal cure is ciprofloxacin (CIP). CIP has exhibited as a recalcitrant compound in nature with concentration from ng to mg. To overcome this issue, recent technologies have applied such as photocatalysis technology for water decontamination. Furthermore, photocatalyst materials that used in this research were zinc ferrite and graphitic carbon nitride. A simple hydrothermal-coprecipitation method has succeed to synthesis zinc ferri

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ABE, TOSHIYUKI, HIROSHI IMAYA, TSUKASA YOSHIDA, et al. "Electrochemical CO2 Reduction Catalysed by Cobalt Octacyanophthalocyanine and its Mechanism." Journal of Porphyrins and Phthalocyanines 01, no. 04 (1997): 315–21. http://dx.doi.org/10.1002/(sici)1099-1409(199710)1:4<315::aid-jpp35>3.0.co;2-v.

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Electrochemical CO 2 reduction was studied by using a graphite electrode coated with cobalt octacyanophthalocyanine ( CoPc ( CN )8) and dipped in an aqueous phase. The most active and selective CO 2 reduction was achieved at −1.20 V (vs Ag / AgCl ) with the ratio of the produced CO / H 2 around 10 at pH 9.3. The electrocatalytic CO 2 reduction by CoPc ( CN )8 could be achieved at a more positive applied potential than non-substituted CoPc ( CoPc ), which can be ascribed to the relatively positive redox potential of CoPc ( CN )8. The catalytic mechanism of the CoPc ( CN )8 in a homogeneous syst

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Al Garalleh, Hakim. "Fullerene Derivatives (CN-[OH]β) and Single-Walled Carbon Nanotubes Modelled as Transporters for Doxorubicin Drug in Cancer Therapy". International Journal of Molecular Sciences 23, № 17 (2022): 9646. http://dx.doi.org/10.3390/ijms23179646.

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Carbon nanomaterials have received increasing attention in drug-delivery applications because of their distinct properties and structures, including large surface areas, high conductivity, low solubility in aqueous media, unique chemical functionalities, and stability at the nano-scale size. Particularly, they have been used as nano-carriers and mediators for anticancer drugs such as Cisplatin, Camptothecin, and Doxorubicin. Cancer has become the most challenging disease because it requires sophisticated therapy, and it is classified as one of the top killers according to the World Health Orga

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